Page last updated: 2024-08-17

mannitol and cimetidine

mannitol has been researched along with cimetidine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's5 (21.74)18.2507
2000's8 (34.78)29.6817
2010's8 (34.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Luthman, K; Norinder, U; Stenberg, P1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ishida, M; Kondo, S; Maeba, T; Maeda, A1
Ellis, D; Galvis, AG; Gartner, JC1
Horwitz, LD; Myers, JH1
Adkin, DA; Davis, SS; Huckle, PD; Sparrow, RA; Wilding, IR1
Ayrton, J; Collett, A; He, YL; Rowland, M; Sims, E; Walker, D; Warhurst, G1
Hatakeyama, Y; Saitoh, H; Sasaya, M; Takada, M1
Atanassova, M; Kirkova, M; Russanov, E1
Hashimoto, Y; Inui, KI; Katsura, T; Mizuuchi, H1
Crespi, CL; Fox, L; Hu, M; Steimel, DT; Stocker, P1
Grossouw, D; Krul, CA; van de Steeg, E; Verwei, M; Westerhout, J; Wortelboer, HM; Zeijdner, EE1

Reviews

1 review(s) available for mannitol and cimetidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for mannitol and cimetidine

ArticleYear
The effect of mannitol on the oral bioavailability of cimetidine.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:12

    Topics: Administration, Oral; Adult; Anti-Ulcer Agents; Biological Availability; Cimetidine; Cross-Over Studies; Humans; Male; Mannitol; Solutions; Sucrose; Tablets

1995

Other Studies

21 other study(ies) available for mannitol and cimetidine

ArticleYear
Experimental and computational screening models for the prediction of intestinal drug absorption.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil

2001
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Exploring the role of different drug transport routes in permeability screening.
    Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2

    Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics

2005
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
[Acute renal failure associated with miscellaneous drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:6

    Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Cimetidine; Furosemide; Humans; Lithium; Lovastatin; Mannitol; Methoxyflurane; Phenytoin; Rhabdomyolysis

1991
Acute renal failure in infants and children: diagnosis, complications, and treatment.
    Critical care medicine, 1981, Volume: 9, Issue:8

    Topics: Acidosis; Acute Kidney Injury; Age Factors; Amino Acids, Essential; Anti-Bacterial Agents; Burns; Child; Cimetidine; Creatinine; Electrolytes; Energy Intake; Enteral Nutrition; Furosemide; Hemoglobinuria; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Kidney; Mannitol; Myoglobinuria; Peritoneal Dialysis; Poisoning; Postoperative Complications; Radionuclide Imaging; Renal Dialysis; Water-Electrolyte Balance

1981
Ethanol-induced alterations in pancreatic blood flow in conscious dogs.
    Circulation research, 1982, Volume: 50, Issue:2

    Topics: Animals; Cimetidine; Dogs; Ethanol; Mannitol; Meclofenamic Acid; Pancreas; Pancreatitis; Phenoxybenzamine; Propranolol; Regional Blood Flow; Vascular Resistance

1982
Comparison of HT29-18-C1 and Caco-2 cell lines as models for studying intestinal paracellular drug absorption.
    Pharmaceutical research, 1996, Volume: 13, Issue:2

    Topics: Atenolol; Biological Transport; Caco-2 Cells; Cell Division; Cell Membrane Permeability; Cimetidine; HT29 Cells; Humans; Hydrochlorothiazide; Intestinal Absorption; Mannitol; Ranitidine; Tritium

1996
Stereoselective permeation of new fluorinated quinolone derivatives across LLC-PK1 cell monolayers.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:7

    Topics: Animals; Anti-Infective Agents; Biological Transport; Cations; Cell Membrane Permeability; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Guanidine; Kidney; Levofloxacin; LLC-PK1 Cells; Mannitol; Ofloxacin; Stereoisomerism; Swine; Tritium

1999
Effects of cimetidine and its metal complexes on nitroblue tetrazolium and ferricytochrome c reduction by superoxide radicals.
    General pharmacology, 1999, Volume: 33, Issue:3

    Topics: Cimetidine; Copper; Cytochrome c Group; Dose-Response Relationship, Drug; Edetic Acid; Mannitol; Metals; Nitroblue Tetrazolium; Oxidation-Reduction; Superoxides

1999
Transport of procainamide via H(+)/tertiary amine antiport system in rabbit intestinal brush-border membrane.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:4

    Topics: Amines; Animals; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cimetidine; Ethylamines; Guanidine; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Small; Kinetics; Male; Mannitol; Microvilli; Potassium; Procainamide; Rabbits; Sodium

2000
Analysis of drug transport and metabolism in cell monolayer systems that have been modified by cytochrome P4503A4 cDNA-expression.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 12, Issue:1

    Topics: Animals; Atenolol; Biological Transport; Cell Line; Cell Membrane Permeability; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Erythromycin; Glucose; Humans; Mammals; Mannitol; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenylalanine; Propranolol; Recombinant Proteins; Testosterone; Tumor Cells, Cultured; Verapamil

2000
A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Oct-15, Volume: 63

    Topics: Animals; Atenolol; Caco-2 Cells; Cimetidine; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Jejunum; Mannitol; Permeability; Ranitidine; Swine; Tumor Cells, Cultured

2014