Page last updated: 2024-08-17

mannitol and antipyrine

mannitol has been researched along with antipyrine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.63)18.7374
1990's7 (21.88)18.2507
2000's16 (50.00)29.6817
2010's4 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghuloum, AM; Jain, AN; Sage, CR1
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Ertl, P; Rohde, B; Selzer, P1
Artursson, P; Luthman, K; Norinder, U; Stenberg, P1
Faassen, F; Spanings, H; Vogel, G; Vromans, H1
Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S1
Caron, G; Ermondi, G1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Chatterjee, J; Gilon, C; Hoffman, A; Kessler, H; Marinelli, L; Ovadia, O; Zahn, G1
Gilon, C; Hess, S; Hoffman, A; Jelinek, R; Ovadia, O; Qadri, B; Salitra, Y; Senderovich, H; Shalev, DE; Sheynis, T; Yehezkel, T1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Shirane, R; Weinstein, PR1
Ardizzone, C; Lippe, C; Margiotta, M1
Case, RM; Cook, DI; Hunter, M; Steward, MC; Young, JA1
Pietras, RJ; Wright, EM1
Kennedy, TG; McRae, AC1
McRae, AC1
Nadai, T; Sakane, T; Taki, Y; Yamashita, S; Yoshida, M1
Anwar, M; Weiss, HR; Williams, JA1
Abraham, MH; Bradbury, MW; Chadha, HS; Gratton, JA1
Ogihara, T; Tamai, I; Tsuji, A1
Hulce, M; Reidelberger, RD; Woltman, TA1
Amidon, GL; Hilgendorf, C; Langguth, P; Lipka, E; Regårdh, CG; Spahn-Langguth, H1
Carraway, RE; Gui, X1
Gandia, P; Houin, G; Lacombe, O; Woodley, J1
Fujita, T; Isomura, Y; Kamiya, M; Ogihara, T; Ohnishi, S; Ozawa, M; Yamamoto, A; Yamashita, S1
Bellantuono, V; Cassano, G; Lippe, C; Quaranta, A1

Reviews

1 review(s) available for mannitol and antipyrine

ArticleYear
The blood-uterine lumen barrier and its possible significance in early embryo development.
    Oxford reviews of reproductive biology, 1984, Volume: 6

    Topics: Animals; Antipyrine; Barbital; Biological Transport, Active; Blastocyst; Body Water; Electrolytes; Embryo Implantation; Embryo Transfer; Embryo, Mammalian; Estradiol; Female; Humans; Mannitol; Maternal-Fetal Exchange; Permeability; Pregnancy; Progesterone; Prostaglandins; Proteins; Steroids; Tissue Distribution; Uterus

1984

Other Studies

31 other study(ies) available for mannitol and antipyrine

ArticleYear
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
    Journal of medicinal chemistry, 1999, May-20, Volume: 42, Issue:10

    Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship

1999
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
    Journal of medicinal chemistry, 2000, Oct-05, Volume: 43, Issue:20

    Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results

2000
Experimental and computational screening models for the prediction of intestinal drug absorption.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil

2001
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
    International journal of pharmaceutics, 2003, Sep-16, Volume: 263, Issue:1-2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport

2003
Exploring the role of different drug transport routes in permeability screening.
    Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2

    Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics

2005
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Multiple N-methylation by a designed approach enhances receptor selectivity.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Binding Sites; Drug Design; Integrin alpha5beta1; Integrin alphaVbeta3; Ligands; Methylation; Models, Molecular; Molecular Conformation; Oligopeptides; Peptides, Cyclic; Platelet Glycoprotein GPIIb-IIIa Complex; Structure-Activity Relationship

2007
Effect of structural and conformation modifications, including backbone cyclization, of hydrophilic hexapeptides on their intestinal permeability and enzymatic stability.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Animals; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Cyclization; Humans; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Liposomes; Magnetic Resonance Spectroscopy; Mannitol; Methylation; Microvilli; Oligopeptides; Peptides, Cyclic; Protein Conformation; Rats; Structure-Activity Relationship

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Effect of mannitol on local cerebral blood flow after temporary complete cerebral ischemia in rats.
    Journal of neurosurgery, 1992, Volume: 76, Issue:3

    Topics: Animals; Antipyrine; Autoradiography; Blood Gas Analysis; Blood Pressure; Carbon Radioisotopes; Cerebrovascular Circulation; Electroencephalography; Heart Rate; Ischemic Attack, Transient; Male; Mannitol; Rats; Rats, Inbred Strains; Reperfusion Injury

1992
Action of forskolin on non-electrolyte permeability across the frog skin as compared to that of vasopressin and isoprenaline.
    Archives internationales de physiologie et de biochimie, 1987, Volume: 95, Issue:2

    Topics: Animals; Antipyrine; Cell Membrane Permeability; Colforsin; Erythritol; In Vitro Techniques; Isoproterenol; Mannitol; Rana esculenta; Skin; Urea; Vasopressins

1987
Transepithelial transport of nonelectrolytes in the rabbit mandibular salivary gland.
    The Journal of membrane biology, 1985, Volume: 84, Issue:3

    Topics: Alcohols; Animals; Antipyrine; Biological Transport; Epithelium; In Vitro Techniques; Inulin; Kinetics; Male; Mandible; Mannitol; Mathematics; Models, Biological; Perfusion; Rabbits; Salivary Glands; Sucrose; Urea

1985
Routes of nonelectrolyte permeation across epithelial membranes.
    The Journal of membrane biology, 1974, Jul-12, Volume: 17, Issue:3

    Topics: Acetamides; Alcohols; Animals; Antipyrine; Bufo marinus; Caffeine; Choroid Plexus; Epithelium; Erythritol; Gallbladder; Glycerol; Kinetics; Mannitol; Mathematics; Membranes; Niacinamide; Organ Specificity; Permeability; Rabbits; Rana catesbeiana; Sucrose; Urea; Urinary Bladder; Water

1974
Selective permeability of the blood-uterine lumen barrier in rats: importance of lipid solubility.
    Biology of reproduction, 1983, Volume: 29, Issue:4

    Topics: Animals; Antipyrine; Barbital; Capillary Permeability; Female; Lipid Metabolism; Mannitol; Rats; Rats, Inbred Strains; Solubility; Uterus

1983
Kinetic analysis of the drug permeation process across the intestinal epithelium.
    Pharmaceutical research, 1994, Volume: 11, Issue:11

    Topics: Animals; Antipyrine; Imipramine; Intestinal Mucosa; Male; Mannitol; Permeability; Pharmacokinetics; Propranolol; Rats; Rats, Wistar; Water

1994
Effects of hyperosmolar mannitol on regional oxygen supply and consumption in the newborn pig.
    Neurological research, 1997, Volume: 19, Issue:2

    Topics: Aminoisobutyric Acids; Animals; Animals, Newborn; Antipyrine; Blood-Brain Barrier; Brain; Cerebrovascular Circulation; Enzyme Inhibitors; Female; Hypertonic Solutions; Male; Mannitol; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Osmolar Concentration; Oxygen; Oxygen Consumption; Spectrophotometry; Swine; Tissue Distribution; Urea

1997
Molecular factors influencing drug transfer across the blood-brain barrier.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:12

    Topics: 2-Propanol; Animals; Antipyrine; Biological Transport; Blood-Brain Barrier; Capillary Permeability; Erythritol; Estradiol; Ethanol; Ethylene Glycol; Female; Kinetics; Linear Models; Mannitol; Models, Biological; Organic Chemicals; Propranolol; Rats; Rats, Wistar; Solubility; Sucrose; Thiourea; Thymine; Urea

1997
Application of fractal kinetics for carrier-mediated transport of drugs across intestinal epithelial membrane.
    Pharmaceutical research, 1998, Volume: 15, Issue:4

    Topics: 3-O-Methylglucose; Animals; Antipyrine; Benzoates; Benzoic Acid; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Cephradine; Diffusion; Epithelium; Fractals; Humans; Ileum; Kinetics; Lactic Acid; Mannitol; Pharmaceutical Preparations; Phenylalanine; Rabbits

1998
Relative blood-brain barrier permeabilities of the cholecystokinin receptor antagonists devazepide and A-65186 in rats.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:8

    Topics: Anesthesia; Animals; Antipyrine; Antiviral Agents; Blood-Brain Barrier; Cerebellum; Devazepide; Diuretics, Osmotic; Hormone Antagonists; Male; Mannitol; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin

1999
Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport.
    Journal of pharmaceutical sciences, 2000, Volume: 89, Issue:1

    Topics: Antipyrine; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Carrier Proteins; Cell Membrane Permeability; Cellular Senescence; Coculture Techniques; Furosemide; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Ketoprofen; Mannitol; Metoprolol; Microscopy, Electron; Piroxicam; Reproducibility of Results; Terbutaline

2000
Enhancement of jejunal absorption of conjugated bile acid by neurotensin in rats.
    Gastroenterology, 2001, Volume: 120, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Chelating Agents; Cholates; Chromium Radioisotopes; Diuretics, Osmotic; Edetic Acid; Glucose; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Leucine; Male; Mannitol; Neurotensin; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Tritium

2001
The perfused everted intestinal segment of rat. 1st communication: absorption kinetics of markers of different permeation mechanisms.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:8

    Topics: Algorithms; Animals; Antipyrine; Cardiotonic Agents; Digoxin; In Vitro Techniques; Intestinal Absorption; Intestines; Mannitol; Models, Biological; Perfusion; Permeability; Proteins; Rats

2004
What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine.
    Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:3

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Antipyrine; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Duodenum; Gene Expression; Humans; Ileum; Injections, Intravenous; Intestinal Absorption; Liver; Mannitol; Mice; Mice, Knockout; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium; Verapamil; Vinblastine

2006
Why amphibians are more sensitive than mammals to xenobiotics.
    PloS one, 2009, Nov-04, Volume: 4, Issue:11

    Topics: Amphibians; Animals; Antipyrine; Atrazine; Ear; Environment; Glycine; Glyphosate; Mammals; Mannitol; Paraquat; Rana esculenta; Skin; Species Specificity; Swine; Xenobiotics

2009