mannich-bases has been researched along with malonic-acid* in 1 studies
1 other study(ies) available for mannich-bases and malonic-acid
Article | Year |
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Direct enantio- and diastereoselective Mannich reactions of malonate and beta-keto esters with N-Boc and N-Cbz aldimines catalysed by a bifunctional cinchonine derivative.
A highly enantioselective Mannich reaction between malonate esters and N-Boc and N-Cbz aldimines, catalysed by a bifunctional cinchonine derivative, has been developed; extension of this methodology to encompass the use of 2-substituted-1,3-dicarbonyl nucleophiles allows the formation of adjacent stereocentres, one of which is quaternary, in high relative and absolute stereocontrol. Topics: Catalysis; Cinchona Alkaloids; Esters; Imines; Ketones; Malonates; Mannich Bases; Models, Molecular; Molecular Structure; Stereoisomerism | 2006 |