mannich-bases has been researched along with fluoroacetic-acid* in 1 studies
1 other study(ies) available for mannich-bases and fluoroacetic-acid
Article | Year |
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Efficient synthesis of beta2-amino acid by homologation of alpha-amino acids involving the Reformatsky reaction and Mannich-type imminium electrophile.
Development of new methods for the synthesis of beta-amino acids is important as polymers of these compounds are promising peptidomimetic candidates in medicinal chemistry. We report here our findings on a new and highly efficient general strategy for the synthesis of beta2-amino acids by homologation of alpha-amino acids, involving the Reformatsky reaction and Mannich-type imminium electrophile. Topics: Amination; Amino Acids; Bromine; Electrons; Esters; Fluoroacetates; Mannich Bases; Methylation; Molecular Structure; Quaternary Ammonium Compounds; Stereoisomerism | 2006 |