mannich-bases and butenolide

mannich-bases has been researched along with butenolide* in 1 studies

Other Studies

1 other study(ies) available for mannich-bases and butenolide

Article	Year
Direct catalytic asymmetric Mannich-type reactions of gamma-butenolides: effectiveness of Brønsted acid in chiral metal catalysis. Organic letters, 2008, Jun-05, Volume: 10, Issue:11 Direct catalytic asymmetric Mannich-type reactions of gamma-butenolides are described. A chiral Lewis acid/amine base/Brønsted acid combination was used to catalyze a gamma-addition of gamma-butenolides to N-diphenylphosphinoyl imines, affording the products in up to >99% yield, anti/syn = >97:3, and 84% ee. The use of a catalytic amount of TfOH in addition to La(OTf)3/Me-PyBox/TMEDA was important for improving yield and stereoselectivity. Topics: 4-Butyrolactone; Acids; Catalysis; Imines; Mannich Bases; Metals; Stereoisomerism; Substrate Specificity	2008

Article

Year

Direct catalytic asymmetric Mannich-type reactions of gamma-butenolides: effectiveness of Brønsted acid in chiral metal catalysis.

Organic letters, 2008, Jun-05, Volume: 10, Issue:11

Direct catalytic asymmetric Mannich-type reactions of gamma-butenolides are described. A chiral Lewis acid/amine base/Brønsted acid combination was used to catalyze a gamma-addition of gamma-butenolides to N-diphenylphosphinoyl imines, affording the products in up to >99% yield, anti/syn = >97:3, and 84% ee. The use of a catalytic amount of TfOH in addition to La(OTf)3/Me-PyBox/TMEDA was important for improving yield and stereoselectivity.

Topics: 4-Butyrolactone; Acids; Catalysis; Imines; Mannich Bases; Metals; Stereoisomerism; Substrate Specificity

2008