Page last updated: 2024-08-21

malondialdehyde and probucol

malondialdehyde has been researched along with probucol in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.43)18.7374
1990's11 (31.43)18.2507
2000's12 (34.29)29.6817
2010's8 (22.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klahr, S; Modi, KS; Morrissey, J; Schreiner, GF; Shah, SV1
Minakami, H; Nakano, M; Ohma, C; Sotomatsu, A1
Barnhart, RL; Busch, SJ; Jackson, RL1
Bird, JE; Blantz, RC; Milhoan, K; Mundy, CA; Parthasarathy, S; Wilson, CB; Young, SG1
Baker, SG; Birnbaum, M; Bradlow, BA; Chetty, N; Seftel, HC1
Cooper, ME; Dunlop, M; Jerums, G; Soulis-Liparota, T1
Armstrong, VW; Oellerich, M; Ringe, B; Schütz, E; Wieland, E1
Davis, P; Exner, M; Kerjaschki, D; Neale, TJ; Ojha, PP; Poczewski, H; Rüger, B; Witztum, JL1
Chait, A; Gilmore, M; Kawamura, M1
Demacker, PN; Hijmans, AG; Kleinveld, HA; Stalenhoef, AF1
Nakagawa, S; Ozawa, K1
al-Gharably, NM1
Fukui, M; Ji, D; Koide, H; Li, L; Tang, Z; Tomino, Y1
Lauridsen, ST; Mortensen, A1
Abdel-Naim, AB; Abdel-Wahab, MH; Attia, FF1
Goto, K; Irukayama-Tomobe, Y; Lazaratos, S; Miyauchi, T; Nakahara, A1
Huang, HL; Liao, DF; Liu, GX; Liu, JH; Ou, DM1
Behr, SR; Schwenke, DC1
Deng, HW; Jiang, JL; Li Ns, NS; Li, YJ1
Antonova, KV; Balabolkin, MI; Belenkov, YN; Konovalova, GG; Lankin, VZ; Lisina, MO; Nedosugova, LV; Tikhaze, AK1
Inami, N; Kajiura, T; Nakamori, H; Nomura, S; Takahashi, N; Tsuda, N; Yamada, K1
Gejyo, F; In, H; Ito, S; Izumi, J; Kanazawa, M; Nakano, M; Ohno, T; Tanaka, H; Ueno, M; Wada, Y; Yahata, K1
Hong, SC; Wu, ZH; Zhao, SP1
Cynshi, O; Stocker, R1
Deng, HW; Hu, CP; Jiang, JL; Li, NS; Li, YJ; Rang, WQ; Zhang, XH1
Al-Ghazali, R; Jinzhen, W; Ruixing, Y; Wenwu, L1
Lei, J; Wang, JF; Zhang, YL; Zhou, SX; Zhou, Y1
Baek, JS; Deer, E; Ellett, F; Fang, L; Green, SR; Lee, SH; Lieschke, GJ; Miller, YI; Tsimikas, S; Witztum, JL1
Rong, H; Tan, M1
Cui, X; Guo, C; Hu, G; Li, H; Liu, G; Liu, L; Liu, Y; Shen, J; Tang, Y; Wang, X; Wang, Y; Yu, Y; Zhao, Y1
Lin, Y; Su, X; Wang, Y; Yang, X; Yu, R; Zheng, C; Zhou, G1
Sun, GF; Wang, YH; Wu, JH; Zhu, WB1
Cai, GY; Chen, XM; Huang, MJ; Li, P; Li, QP; Wang, N; Wang, R; Wei, RB; Yang, X1
Che, B; Ho, D; Hou, H; Lin, V; Lu, Z; May, A; Shaw, PX; Tran, K; Xiao, X; Zhang, J1
Fu, Q; Hu, LL; Tian, T; Zhang, H; Zhang, KQ1

Reviews

1 review(s) available for malondialdehyde and probucol

ArticleYear
Inhibition of lipoprotein lipid oxidation.
    Handbook of experimental pharmacology, 2005, Issue:170

    Topics: Animals; Antioxidants; Atherosclerosis; Benzofurans; Cardiovascular Diseases; Humans; Lipoproteins, LDL; Malondialdehyde; Oxidation-Reduction; Probucol; Thiobarbituric Acid Reactive Substances

2005

Trials

2 trial(s) available for malondialdehyde and probucol

ArticleYear
Probucol and ticlopidine: effect on platelet and monocyte activation markers in hyperlipidemic patients with and without type 2 diabetes.
    Atherosclerosis, 2004, Volume: 174, Issue:2

    Topics: Aged; Analysis of Variance; Biomarkers; Diabetes Mellitus, Type 2; Drug Therapy, Combination; E-Selectin; Female; Humans; Hyperlipidemias; Male; Malondialdehyde; Middle Aged; Monocytes; P-Selectin; Platelet Activation; Probability; Probucol; Prospective Studies; Reference Values; Sensitivity and Specificity; Ticlopidine

2004
[Effect of probucol on serum malondialdehyde and superoxide dismutase in patients with primary hypertension].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2012, Volume: 37, Issue:5

    Topics: Adult; Antioxidants; Female; Humans; Hypertension; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Probucol; Superoxide Dismutase

2012

Other Studies

32 other study(ies) available for malondialdehyde and probucol

ArticleYear
Effects of probucol on renal function in rats with bilateral ureteral obstruction.
    Kidney international, 1990, Volume: 38, Issue:5

    Topics: Animals; Female; Free Radical Scavengers; Free Radicals; Glutathione; Kidney; Lipid Peroxidation; Malondialdehyde; Premedication; Probucol; Rats; Rats, Inbred Strains; Time Factors; Ureteral Obstruction

1990
Antioxidant activity of probucol. Short communication.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:9

    Topics: Animals; Antioxidants; Doxorubicin; Estrone; In Vitro Techniques; Lipid Peroxidation; Malondialdehyde; Microsomes, Liver; NADP; Oxygen Consumption; Phenols; Phospholipids; Probucol; Rats

1989
Concentration-dependent antioxidant activity of probucol in low density lipoproteins in vitro: probucol degradation precedes lipoprotein oxidation.
    Journal of lipid research, 1989, Volume: 30, Issue:11

    Topics: Apolipoprotein B-100; Apolipoproteins B; Chromatography, High Pressure Liquid; Copper; Humans; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Malondialdehyde; Molecular Weight; Oxidation-Reduction; Phenols; Probucol; Thiobarbiturates

1989
Ischemic acute renal failure and antioxidant therapy in the rat. The relation between glomerular and tubular dysfunction.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:5

    Topics: Acute Kidney Injury; Animals; Chemical Phenomena; Chemistry; Glomerular Filtration Rate; Inulin; Ischemia; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Malondialdehyde; Peroxidase; Phenols; Probucol; Rats

1988
Platelet function in familial hypercholesterolaemia in South Africa and the effects of probucol.
    Thrombosis research, 1982, Apr-15, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Aged; beta-Thromboglobulin; Child; Cholesterol; Coronary Disease; Female; Humans; Hyperlipoproteinemia Type II; Male; Malondialdehyde; Middle Aged; Phenols; Platelet Aggregation; Probucol; South Africa

1982
The relative roles of advanced glycation, oxidation and aldose reductase inhibition in the development of experimental diabetic nephropathy in the Sprague-Dawley rat.
    Diabetologia, 1995, Volume: 38, Issue:4

    Topics: Albuminuria; Aldehyde Reductase; Animals; Antioxidants; Blood Glucose; Body Weight; Butylated Hydroxytoluene; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycated Hemoglobin; Glycosylation; Guanidines; Kidney Cortex; Male; Malondialdehyde; Oxidation-Reduction; Phthalazines; Probucol; Rats; Rats, Sprague-Dawley; Sorbitol

1995
QSA 10 (idebenone) or probucol supplementation of organ preservation solutions prevents oxygen radical-mediated injury of hepatic microsomes.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Blotting, Western; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Free Radicals; Glutathione; Glutathione Transferase; Insulin; Lipid Peroxidation; Liver; Male; Malondialdehyde; Microsomes, Liver; Organ Preservation; Organ Preservation Solutions; Oxidoreductases, N-Demethylating; Probucol; Raffinose; Rats; Rats, Wistar; Ubiquinone

1995
Proteinuria in passive Heymann nephritis is associated with lipid peroxidation and formation of adducts on type IV collagen.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:4

    Topics: Aldehydes; Animals; Anticholesteremic Agents; Antigen-Antibody Complex; Basement Membrane; Cholesterol; Collagen; Disease Models, Animal; Epithelial Cells; Glomerulonephritis; Kidney Glomerulus; Lipid Peroxidation; Lovastatin; Lysine; Male; Malondialdehyde; Probucol; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Simvastatin

1994
Inhibition of low density lipoprotein oxidation in vitro by the 6- and 7-hydroxy-metabolites of doxazosin, an alpha 1-adrenergic antihypertensive agent.
    American journal of hypertension, 1994, Volume: 7, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Antihypertensive Agents; Antioxidants; Chromatography, Liquid; Doxazosin; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Lipoproteins, LDL; Malondialdehyde; Monocytes; Oxidation-Reduction; Probucol; Thiobarbituric Acid Reactive Substances; Ultracentrifugation

1994
Indications for the presence of circulating peroxidized low density lipoproteins in WHHL rabbits treated with antioxidants.
    Atherosclerosis, 1993, Volume: 102, Issue:1

    Topics: Animals; Antioxidants; Apolipoprotein B-100; Apolipoproteins B; Hyperlipidemias; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Malondialdehyde; Molecular Weight; Probucol; Rabbits; Vitamin E

1993
Protective aspects for atherogenesis and lipid abnormalities in continuous ambulatory peritoneal dialysis patients.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1993, Volume: 13 Suppl 2

    Topics: Aged; Aged, 80 and over; Arteriosclerosis; Creatinine; Female; Glutathione Peroxidase; Humans; Hyperlipidemias; Lipoprotein(a); Male; Malondialdehyde; Methylguanidine; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Probucol; Risk Factors; Selenium; Superoxide Dismutase

1993
Effect of probucol on the cytological and biochemical changes induced by adriamycin in Swiss albino mice.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 94, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Anticholesteremic Agents; DNA; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Erythrocytes; Liver; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Probucol; Proteins; RNA

1996
Effect of probucol on mRNA expression of glomerular antioxidant enzymes in rat with subtotal nephrectomy.
    Chinese medical journal, 1996, Volume: 109, Issue:10

    Topics: Animals; Antioxidants; Glutathione Peroxidase; Kidney Glomerulus; Male; Malondialdehyde; Nephrectomy; Probucol; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase

1996
Probucol selectively increases oxidation of atherogenic lipoproteins in cholesterol-fed mice and in Watanabe heritable hyperlipidemic rabbits.
    Atherosclerosis, 1999, Volume: 142, Issue:1

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Hyperlipidemias; Lipid Peroxidation; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Probucol; Quercetin; Rabbits; Triglycerides

1999
Protective effects of vitamin e and probucol against gentamicin-induced nephrotoxicity in rats.
    Pharmacological research, 1999, Volume: 40, Issue:2

    Topics: Acetylglucosaminidase; Animals; Anticholesteremic Agents; Creatinine; Drug Synergism; gamma-Glutamyltransferase; Gentamicins; Kidney; Kidney Diseases; Male; Malondialdehyde; Probucol; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Superoxide Dismutase; Urea; Vitamin E

1999
Oxygen radicals mediate the final exacerbation of endothelin-1-induced gastric ulcer in rat.
    European journal of pharmacology, 2001, Feb-09, Volume: 413, Issue:1

    Topics: Adenosine Triphosphate; Aldehydes; Allopurinol; Animals; Catalase; Deferoxamine; Disease Progression; Endothelin-1; Gastric Mucosa; Male; Malondialdehyde; Oxypurinol; Peptic Ulcer; Probucol; Rats; Rats, Wistar; Regional Blood Flow; Superoxide Dismutase; Superoxides; Vasoconstriction; Xanthine Oxidase

2001
Probucol inhibits lipid peroxidation of macrophage and affects its secretory properties.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:7

    Topics: Anticholesteremic Agents; Apolipoproteins E; Cells, Cultured; Humans; Interleukin-1; Lipid Peroxidation; Macrophages; Malondialdehyde; Probucol

2000
Alpha-tocopherol and probucol reduce autoantibody titer to MDA-LDL in hypercholesterolemic rabbits.
    Free radical biology & medicine, 2001, Sep-15, Volume: 31, Issue:6

    Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Antioxidants; Aorta; Arteriosclerosis; Autoantibodies; Cholesterol; Cholesterol, Dietary; Female; Hypercholesterolemia; Lipoproteins, LDL; Malondialdehyde; Probucol; Rabbits

2001
Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level.
    British journal of pharmacology, 2002, Volume: 135, Issue:5

    Topics: Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Lipoproteins, LDL; Male; Malondialdehyde; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Probucol; Rats; Rats, Sprague-Dawley; Vasodilation

2002
Interrelation between compensation of carbohydrate metabolism and severity of manifestations of oxidative stress in type II diabetes mellitus.
    Bulletin of experimental biology and medicine, 2003, Volume: 136, Issue:2

    Topics: Aged; Antioxidants; Carbohydrate Metabolism; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Oxidative Stress; Probucol; Reactive Oxygen Species

2003
Mixed connective tissue disease associated with antineutrophil cytoplasmic antibodies against proteinase-3 and systemic atherosclerosis: a case report.
    Clinical rheumatology, 2004, Volume: 23, Issue:5

    Topics: Antibodies, Antineutrophil Cytoplasmic; Arteriosclerosis; Aspirin; Autoantibodies; Cholesterol, LDL; Female; Granulomatosis with Polyangiitis; Humans; Lipid Peroxidation; Malondialdehyde; Middle Aged; Mixed Connective Tissue Disease; Myeloblastin; Prednisolone; Probucol; Serine Endopeptidases; Treatment Outcome; Valproic Acid

2004
Probucol up-regulates paraoxonase 1 expression in hepatocytes of hypercholesterolemic rabbits.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:1

    Topics: Animals; Anticholesteremic Agents; Antioxidants; Aryldialkylphosphatase; Body Weight; Gene Expression Regulation, Enzymologic; Hepatocytes; Hypercholesterolemia; Lipids; Male; Malondialdehyde; Probucol; Rabbits; RNA, Messenger; Superoxide Dismutase

2006
Probucol decreases asymmetrical dimethylarginine level by alternation of protein arginine methyltransferase I and dimethylarginine dimethylaminohydrolase activity.
    Cardiovascular drugs and therapy, 2006, Volume: 20, Issue:4

    Topics: Amidohydrolases; Antioxidants; Arginine; Cell Line; Endothelial Cells; Humans; L-Lactate Dehydrogenase; Lipoproteins, LDL; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Probucol; Protein-Arginine N-Methyltransferases

2006
Pretreatment with probucol attenuates cardiomyocyte apoptosis in a rabbit model of ischemia/reperfusion.
    Scandinavian journal of clinical and laboratory investigation, 2006, Volume: 66, Issue:7

    Topics: Animals; Apoptosis; Cardiotonic Agents; Disease Models, Animal; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocytes, Cardiac; Probucol; Rabbits; Superoxide Dismutase

2006
Antioxidant probucol attenuates myocardial oxidative stress and collagen expressions in post-myocardial infarction rats.
    Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:2

    Topics: Animals; Antioxidants; Collagen; Collagen Type I; Collagen Type III; Diastole; Disease Models, Animal; Gene Expression Regulation; Male; Malondialdehyde; Myocardial Infarction; Myocardium; Oxidative Stress; Probucol; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase

2009
In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish.
    The Journal of clinical investigation, 2011, Volume: 121, Issue:12

    Topics: Animals; Animals, Genetically Modified; Antibodies, Monoclonal; Anticholesteremic Agents; Blood Vessels; Cholesterol, Dietary; Disease Models, Animal; Drug Evaluation, Preclinical; Epitopes; Genes, Reporter; Green Fluorescent Proteins; Humans; Hydrazines; Hypercholesterolemia; Immunoglobulin Fab Fragments; Lipoproteins, LDL; Macrophages; Malondialdehyde; Microscopy, Confocal; Microscopy, Fluorescence; Oxidation-Reduction; Porphobilinogen; Probucol; Recombinant Fusion Proteins; Single-Chain Antibodies; Temperature; Veins; Zebrafish; Zebrafish Proteins

2011
Development of a novel model of hypertriglyceridemic acute pancreatitis in hamsters: protective effects of probucol.
    Pancreas, 2012, Volume: 41, Issue:6

    Topics: Acute Disease; Amylases; Animals; Antioxidants; Biomarkers; Ceruletide; Cricetinae; Diet, High-Fat; Disease Models, Animal; Glutathione; Hydrogen Peroxide; Hypertriglyceridemia; Lipase; Malondialdehyde; Oxidative Stress; Pancreas; Pancreatitis; Probucol; Severity of Illness Index

2012
Probucol attenuates ethanol-induced liver fibrosis in rats by inhibiting oxidative stress, extracellular matrix protein accumulation and cytokine production.
    Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:1

    Topics: Actins; Animals; Anticholesteremic Agents; Blotting, Western; Carbon Tetrachloride Poisoning; Central Nervous System Depressants; Collagen Type I; Cytokines; Ethanol; Extracellular Matrix Proteins; Glutathione; Hydroxyproline; In Situ Nick-End Labeling; Liver; Liver Cirrhosis; Liver Function Tests; Male; Malondialdehyde; MAP Kinase Signaling System; Oxidative Stress; Probucol; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Superoxide Dismutase

2014
Protective effect and mechanism of probucol in the treatment of spinal cord injury.
    Genetics and molecular research : GMR, 2015, Jul-17, Volume: 14, Issue:3

    Topics: Animals; Blotting, Western; Cytokines; Female; Inflammation; Inflammation Mediators; Malondialdehyde; Motor Activity; Neuroprotective Agents; Oxidative Stress; Probucol; Rats, Wistar; Recovery of Function; Spinal Cord Injuries; Superoxide Dismutase

2015
Renal Protective Effect of Probucol in Rats with Contrast-Induced Nephropathy and its Underlying Mechanism.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Sep-26, Volume: 21

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Contrast Media; Creatinine; Deoxyguanosine; Disease Models, Animal; Immunohistochemistry; Kidney; Kidney Diseases; Male; Malondialdehyde; Nitrogen; Oxidative Stress; Probucol; Rats; Rats, Wistar; Superoxide Dismutase

2015
Probucol Protects Rats from Cardiac Dysfunction Induced by Oxidative Stress following Cardiopulmonary Resuscitation.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Animals; Antioxidants; Cardiopulmonary Resuscitation; Disease Models, Animal; Glutathione Peroxidase; Heart Arrest; Hemodynamics; Kaplan-Meier Estimate; Kelch-Like ECH-Associated Protein 1; Male; Malondialdehyde; Myocardium; NF-E2-Related Factor 2; Oxidative Stress; Probucol; Protective Agents; Rats; Rats, Sprague-Dawley

2017
Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1 / DDAH / PPAR-γ/ eNOS pathways in streptozotocin-induced diabetic rats.
    Biochemical and biophysical research communications, 2018, 12-09, Volume: 507, Issue:1-4

    Topics: Amidohydrolases; Animals; Arginine; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Erectile Dysfunction; Heme Oxygenase-1; Male; Malondialdehyde; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; PPAR gamma; Probucol; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Superoxide Dismutase

2018