Page last updated: 2024-08-21

malondialdehyde and phenobarbital

malondialdehyde has been researched along with phenobarbital in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199011 (42.31)18.7374
1990's5 (19.23)18.2507
2000's4 (15.38)29.6817
2010's6 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anders, MW; Lindstrom, TD; Remmer, H1
Hornbrook, KR; McCay, PB; Weddle, CC1
Carlson, GP; Fuller, GC; Suarez, KA1
Charles, SJ; Connolly, AK; Powell, CJ1
Jayatilaka, KA; Perera, DJ; Thabrew, MI1
Brun-Pascaud, M; Gougerot-Pocidalo, MA; Hakim, J; Mansour, H; Marquetty, C; Pocidalo, JJ1
Hamajima, K; Narimatsu, S; Watanabe, K; Yamamoto, I; Yoshimura, H1
Becker, E; Berndt, J; Messner, B1
Freeman, RW; Harbison, RD; Teaf, CM1
Bast, A; Brenninkmeijer, JW; Noordhoek, J; Savenije-Chapel, EM1
Cadenas, E; Sies, H1
Béraud, M; Delmas, C; Derache, P1
Baird, MB1
Alvarez, A; Boscá, L; Cascales, M; Fernández-Simón, L; Gascó, P; Sanz, N1
Horie, Y; Karbowski, M; Kurono, C; Nishizawa, Y; Soji, T; Wakabayashi, T1
Carletti, M; Ceppa, L; Dacasto, M; Nebbia, C1
Estey, T; Manzer, R; Pappa, A; Petersen, DR; Qamar, L; Vasiliou, V1
Kumar, P; Majumdar, S; Narang, A; Singh, D1
El-Sokkary, GH1
Curti, C; Martins, NM; Medina, WS; Rodrigues, MA; Santos, AC; Santos, NA1
Gupta, YK; Mehla, J; Reeta, KH1
Akin, H; Aydogan, F; Ramadan, SS; Tahan, G; Tahan, V; Tarcin, O; Uzun, H; Yapicier, O; Zengin, K1
Gahlaut, V; Gathwala, G; Marwah, A; Marwah, P1
Arai, Y; Higuchi, H; Maeda, S; Miyawaki, T; Shimada, M; Tomoyasu, Y1
Abdel-Gawad, E; Awwad, S; El-Agamy, B; Kandil, E; Mohammed, M1
Chattipakorn, N; Chattipakorn, SC; Fucharoen, S; Jaiwongkam, T; Kerdphoo, S; Khamseekaew, J; Kumfu, S; Srichairatanakool, S; Wongjaikam, S1

Trials

2 trial(s) available for malondialdehyde and phenobarbital

ArticleYear
Effect of phenobarbital on free radicals in neonates with hypoxic ischemic encephalopathy--a randomized controlled trial.
    Journal of perinatal medicine, 2004, Volume: 32, Issue:3

    Topics: Anticonvulsants; Female; Free Radicals; Glutathione Peroxidase; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infusions, Intravenous; Male; Malondialdehyde; Phenobarbital; Superoxide Dismutase; Treatment Outcome

2004
Effect of high-dose phenobarbital on oxidative stress in perinatal asphyxia: an open label randomized controlled trial.
    Indian pediatrics, 2011, Volume: 48, Issue:8

    Topics: Asphyxia Neonatorum; Glutathione Peroxidase; Hospitals, Teaching; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Intensive Care Units, Neonatal; Lipid Peroxidation; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Phenobarbital; Superoxide Dismutase

2011

Other Studies

24 other study(ies) available for malondialdehyde and phenobarbital

ArticleYear
Effect of phenobarbital and diethyl maleate on carbon tetrachloride toxicity in isolated rat hepatocytes.
    Experimental and molecular pathology, 1978, Volume: 28, Issue:1

    Topics: Animals; Carbon Tetrachloride Poisoning; Glutathione; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Maleates; Malondialdehyde; Phenobarbital; Rats

1978
Lipid peroxidation and alteration of membrane lipids in isolated hepatocytes exposed to carbon tetrachloride.
    The Journal of biological chemistry, 1976, Aug-25, Volume: 251, Issue:16

    Topics: Animals; Carbon Tetrachloride; In Vitro Techniques; Kinetics; Lipid Metabolism; Liver; Male; Malondialdehyde; Peroxides; Phenobarbital; Rats

1976
Effect of phenobarbital or 3-methylcholanthrene pretreatment on carbon tetrachloride-induced lipid peroxidation in rat liver.
    Toxicology and applied pharmacology, 1975, Volume: 34, Issue:2

    Topics: Animals; Carbon Tetrachloride; In Vitro Techniques; Lipid Metabolism; Liver; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; Peroxides; Phenobarbital; Rats

1975
Shifting necrosis: butylated hydroxytoluene (BHT) and phenobarbital move cocaine-induced hepatic necrosis across the lobule.
    Toxicology letters, 1991, Volume: 55, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Butylated Hydroxytoluene; Cocaine; Drug Interactions; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred DBA; Microsomes, Liver; Necrosis; Organ Size; Phenobarbital

1991
Effect of Melothria maderaspatana on carbon tetrachloride-induced changes in rat hepatic microsomal drug-metabolizing enzyme activity.
    Journal of ethnopharmacology, 1990, Volume: 30, Issue:1

    Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutathione; In Vitro Techniques; Kinetics; Lipid Peroxidation; Liver; Male; Malondialdehyde; Microsomes, Liver; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Plant Extracts; Rats; Rats, Inbred Strains; Sleep

1990
Protection of rat from oxygen toxicity by inducers of cytochrome P-450 system.
    The American review of respiratory disease, 1988, Volume: 137, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Lung; Male; Malondialdehyde; Methylcholanthrene; Microsomes; Oxygen; Phenobarbital; Pulmonary Edema; Random Allocation; Rats; Rats, Inbred Strains; Superoxides

1988
Effects of two cannabinoids on hepatic microsomal cytochrome P-450.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Animals; Cannabidiol; Cannabinoids; Cytochrome P-450 Enzyme System; Dronabinol; Heme Oxygenase (Decyclizing); Lipid Peroxides; Male; Malondialdehyde; Methylcholanthrene; Mice; Microsomes, Liver; Phenobarbital

1986
Two mechanisms of CCl4-induced fatty liver: lipid peroxidation or covalent binding studied in cultured rat hepatocytes.
    Free radical research communications, 1987, Volume: 3, Issue:1-5

    Topics: Animals; Binding, Competitive; Carbon Tetrachloride; Cells, Cultured; Fatty Liver; Female; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, VLDL; Liver; Malondialdehyde; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Vitamin E

1987
Cocaine-induced hepatotoxicity: lipid peroxidation as a possible mechanism.
    Drug and chemical toxicology, 1984, Volume: 7, Issue:4

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Lipid Peroxides; Male; Malondialdehyde; Mice; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital

1984
Cytochrome P450 oxidase activity and its role in NADPH dependent lipid peroxidation.
    FEBS letters, 1983, Jan-24, Volume: 151, Issue:2

    Topics: Animals; Kinetics; Lipid Peroxides; Male; Malondialdehyde; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains

1983
Low level chemiluminescence of liver microsomal fractions initiated by tert-butyl hydroperoxide. Relation to microsomal hemoproteins, oxygen dependence, and lipid peroxidation.
    European journal of biochemistry, 1982, May-17, Volume: 124, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme System; Hemeproteins; Kinetics; Lipid Peroxides; Luminescent Measurements; Male; Malondialdehyde; Microsomes, Liver; Oxidation-Reduction; Oxygen Consumption; Peroxides; Phenobarbital; Rats; tert-Butylhydroperoxide

1982
[Effects of chloramphenicol on microsomal reductases associated with lipoperoxidation (author's transl)].
    Toxicological European research. Recherche europeenne en toxicologie, 1982, Volume: 4, Issue:2

    Topics: Animals; Chloramphenicol; Cytochrome P-450 Enzyme System; Lipid Peroxides; Male; Malondialdehyde; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Triglycerides

1982
Microsomal NADPH-dependent lipid peroxidation does not require the presence of intact cytochrome P450.
    Biochemical and biophysical research communications, 1980, Aug-29, Volume: 95, Issue:4

    Topics: Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Heme; In Vitro Techniques; Lipid Peroxides; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Pregnenolone Carbonitrile; Rats

1980
Cocaine-induced liver injury in mice elicits specific changes in DNA ploidy and induces programmed death of hepatocytes.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:4 Pt 1

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Division; Cells, Cultured; Cocaine; Cytochrome P-450 Enzyme System; DNA; DNA Damage; Flow Cytometry; Glutathione; Isocitrate Dehydrogenase; Liver; Liver Regeneration; Male; Malondialdehyde; Mice; NADP; Necrosis; Phenobarbital; Ploidies; Polyploidy; Time Factors

1994
Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes.
    Biochimica et biophysica acta, 1997, Nov-30, Volume: 1349, Issue:3

    Topics: Animals; Bromobenzenes; Cell Survival; Cells, Cultured; Cycloheximide; Cytochrome P-450 Enzyme System; Erythromycin; Free Radicals; Hydrazines; Hydrogen Peroxide; Lipid Peroxides; Liver; Male; Malondialdehyde; Microscopy, Confocal; Microscopy, Electron; Mitochondria, Liver; Oxidative Stress; Phenobarbital; Protein Synthesis Inhibitors; Rats; Rats, Wistar

1997
Triphenyltin acetate-mediated in vitro inactivation of rat liver cytochrome P-450.
    Journal of toxicology and environmental health. Part A, 1999, Mar-26, Volume: 56, Issue:6

    Topics: Aminopyrine N-Demethylase; Animals; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes; Dose-Response Relationship, Drug; Fungicides, Industrial; Male; Malondialdehyde; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Organotin Compounds; Phenobarbital; Rats; Rats, Wistar

1999
Molecular cloning and baculovirus expression of the rabbit corneal aldehyde dehydrogenase (ALDH1A1) cDNA.
    DNA and cell biology, 2003, Volume: 22, Issue:5

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehydes; Amino Acid Sequence; Animals; Baculoviridae; Base Sequence; Blotting, Western; Cloning, Molecular; Cornea; DNA, Complementary; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Humans; Immunoenzyme Techniques; Isoenzymes; Malondialdehyde; Molecular Sequence Data; Phenobarbital; Rabbits; Recombinant Proteins; Retinal Dehydrogenase; Sequence Homology, Amino Acid

2003
An autoradiographic study of cellular proliferaton, DNA synthesis and cell cycle variability in the rat liver caused by phenobarbital-induced oxidative stress: the protective role of melatonin.
    Cellular & molecular biology letters, 2007, Volume: 12, Issue:3

    Topics: Animals; Autoradiography; Cell Cycle; Cell Proliferation; DNA; Lipid Peroxidation; Liver; Male; Malondialdehyde; Melatonin; Oxidative Stress; Phenobarbital; Protective Agents; Radiography; Rats; Rats, Sprague-Dawley; Tritium

2007
Involvement of oxidative stress in the hepatotoxicity induced by aromatic antiepileptic drugs.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:8

    Topics: Animals; Anticonvulsants; Carbamazepine; Cardiolipins; Liver; Male; Malondialdehyde; Microsomes, Liver; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Sulfhydryl Compounds; Toxicity Tests

2008
Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats.
    European journal of pharmacology, 2010, Oct-10, Volume: 644, Issue:1-3

    Topics: Animals; Anticonvulsants; Antioxidants; Avoidance Learning; Brain; Carbamazepine; Cognition Disorders; Curcumin; Drug Interactions; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Memory Disorders; Oxidative Stress; Phenobarbital; Rats; Rats, Wistar

2010
Melatonin ameliorates liver fibrosis induced by bile-duct ligation in rats.
    Canadian journal of surgery. Journal canadien de chirurgie, 2010, Volume: 53, Issue:5

    Topics: Acridines; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Bile Ducts; Bilirubin; Collagen; Cytokines; gamma-Glutamyltransferase; Glutathione; Ligation; Liver; Liver Cirrhosis; Male; Malondialdehyde; Melatonin; Phenobarbital; Rats; Rats, Wistar

2010
Effects of midazolam and phenobarbital on brain oxidative reactions induced by pentylenetetrazole in a convulsion model.
    Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:2

    Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Gene Expression; Heme Oxygenase-1; Hippocampus; Hypothalamus; Male; Malondialdehyde; Mice; Midazolam; Oxidation-Reduction; Pentylenetetrazole; Phenobarbital; Seizures; Treatment Outcome

2012
Therapeutic role of a synthesized calcium phosphate nanocomposite material on hepatocarcinogenesis in rats.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2016, Volume: 94, Issue:3

    Topics: Animals; Calcium Phosphates; Diethylnitrosamine; DNA Fragmentation; Enzymes; Interferon-gamma; Interleukin-2; Liver; Liver Neoplasms, Experimental; Male; Malondialdehyde; Microscopy, Electron, Scanning; Nanocomposites; Phenobarbital; Rats, Wistar; Tumor Necrosis Factor-alpha; X-Ray Diffraction

2016
Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice.
    European journal of pharmacology, 2017, Mar-15, Volume: 799

    Topics: Aminophylline; Animals; Apoptosis; Atropine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, T-Type; Deferiprone; Dihydropyridines; Drug Combinations; Heart; Heart Rate; Iron; Iron Chelating Agents; Iron Overload; Male; Malondialdehyde; Mice; Mitochondria; Myocardium; Nitroglycerin; Nitrophenols; Organelle Biogenesis; Organophosphorus Compounds; Oxidative Phosphorylation; Papaverine; Phenobarbital; Pyridones; Signal Transduction; Thalassemia

2017