Page last updated: 2024-08-21

malondialdehyde and fenofibrate

malondialdehyde has been researched along with fenofibrate in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's0 (0.00)18.2507
2000's7 (26.92)29.6817
2010's15 (57.69)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Barbanti, M; Borzatta, V; Ciriolo, MR; Cristofori, M; Mavelli, I; Rossi, L; Rotilio, G1
Błaszczyk, J; Błaszczyk-Suszyńska, J; Gburek, J; Kedziora, J; Kowalski, J; Kowalski, M; Olejniczak, J; Petecka, E1
Ceska, R; Hilgertová, J; Kvasnicka, J; Skrha, J; Stulc, T; Weiserová, H1
Chen, MF; Jiang, JL; Li, YJ; Luo, BL; Yang, TL; Yu, J1
Holubec, L; Mayer, O; Pikner, R; Simon, J; Trefil, L1
Ahn, JY; Chung, WJ; Han, SH; Kim, JA; Koh, KK; Lee, Y; Quon, MJ; Shin, EK1
Chen, MF; Li, YJ; Luo, BL; Xia, X; Yang, TL1
Akin, O; Alper, M; Cindoruk, M; Erdem, O; Karakan, T; Kerem, M; Salman, B; Unal, S1
Meng, Q; Ruan, X; Shen, C1
Zhou, JY; Zhou, SW1
Boshra, V; Moustafa, AM1
Chen, ZY; Lei, L; Li, LY; Liu, Q; Liu, SN; Shen, ZF; Zhang, N1
Huan, Y; Li, LY; Liu, Q; Liu, SN; Shen, ZF; Sun, SJ1
Akın, O; Alper, M; Cindoruk, M; Engin, D; Karakan, T; Kerem, M1
Abdel Kawy, HS; El-Aziz, LF; El-Kharashi, OA; El-Samad, AA; Elmelegy, AA; Mohamed, DI1
Elshazly, SM; Mahmoud, AA1
Huang, F; Jiang, J; Sun, B; Wang, Y; Xie, Y; Xu, X; Zhao, C1
Cui, Y; Deng, M; Qi, ZG; Shang, X; Wang, XL; Xie, ML; Xue, J; Zhang, Y; Zhao, X1
Liu, H; Ma, X; Zheng, X; Zuo, N1
Abd El-Haleim, EA; Bahgat, AK; Saleh, S1
Refaie, MMM1
Mohammadi, MT; Sahebkar, A; Yaribeygi, H1
Refaie, MMM; Rifaai, RA; Zenhom, NM1
Abdel-Hafez, SMN; Abdelzaher, WY; Ali, AHSA; Bahaa, HA; Hegazy, A; Rofaeil, RR1
Abdelzaher, WY; Bayoumi, AMA; El-Tahawy, NFG; Refaie, MMM; Shehata, S1
Bilušić, M; Božina, T; Bradamante, V; Konjevoda, P; Lovrić, J; Rašić, D; Vukšić, A; Žunec, S1

Trials

5 trial(s) available for malondialdehyde and fenofibrate

ArticleYear
[Effect of fluvastatin and fenofibrate on reactive oxygen species generation and lipid peroxidation in patients with dyslipidemia].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2003, Volume: 14, Issue:82

    Topics: Adult; Aged; Anticholesteremic Agents; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Humans; Hyperlipidemias; Hypolipidemic Agents; Indoles; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Reactive Oxygen Species

2003
Effect of simvastatin and fenofibrate on endothelium in Type 2 diabetes.
    European journal of pharmacology, 2004, Jun-16, Volume: 493, Issue:1-3

    Topics: Acetylglucosaminidase; Adult; Aged; alpha-Tocopherol; Ascorbic Acid; Cholesterol; Czech Republic; Diabetes Mellitus, Type 2; Drug Administration Schedule; E-Selectin; Endothelium; Female; Fenofibrate; Fibrinolysis; Glutathione; Humans; Hyperlipidemias; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Plasminogen Activator Inhibitor 1; Simvastatin; Superoxide Dismutase; Time Factors; Triglycerides; Vascular Endothelial Growth Factor A; von Willebrand Factor

2004
Folate co-administration improves the effectiveness of fenofibrate to decrease the lipoprotein oxidation and endothelial dysfunction surrogates.
    Physiological research, 2006, Volume: 55, Issue:5

    Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Drug Therapy, Combination; Endothelium, Vascular; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Hypolipidemic Agents; Indoles; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Prospective Studies; Thrombomodulin; Treatment Outcome; Triglycerides; Vitamin B Complex; von Willebrand Factor

2006
Additive beneficial effects of fenofibrate combined with candesartan in the treatment of hypertriglyceridemic hypertensive patients.
    Diabetes care, 2006, Volume: 29, Issue:2

    Topics: Adiponectin; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; C-Reactive Protein; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Fenofibrate; Humans; Hypertension; Hypertriglyceridemia; Hypolipidemic Agents; Insulin Resistance; Lipoproteins; Male; Malondialdehyde; Middle Aged; Multivariate Analysis; Regression Analysis; Tetrazoles; Vasomotor System

2006
Effect of fenofibrate on the level of asymmetric dimethylarginine in individuals with hypertriglyceridemia.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:3

    Topics: Adult; Anticholesteremic Agents; Arginine; Blood Flow Velocity; Brachial Artery; Cholesterol; Cholesterol, HDL; Diet; Endothelium, Vascular; Female; Fenofibrate; Humans; Hypertriglyceridemia; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Treatment Outcome; Triglycerides; Tumor Necrosis Factor-alpha; Vasodilation

2006

Other Studies

21 other study(ies) available for malondialdehyde and fenofibrate

ArticleYear
The effects of hypolipidemic agents derived from procetofenic acid on the activity of superoxide dismutase and glutathione peroxidase and on malonyl dialdehyde production of rat liver.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:4

    Topics: Animals; Catalase; Cholesterol; Female; Fenofibrate; Glutathione Peroxidase; Hypolipidemic Agents; In Vitro Techniques; Lipid Peroxides; Liver; Male; Malonates; Malondialdehyde; Propionates; Rats; Rats, Inbred Strains; Sex Factors; Superoxide Dismutase; Triglycerides

1984
Effect of fenofibrate on LDL-induced endothelial dysfunction in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Arginine; Creatinine; Endothelium, Vascular; Fenofibrate; Hypolipidemic Agents; In Vitro Techniques; Male; Malondialdehyde; Muscle, Smooth, Vascular; Nitrates; Nitrites; Phenylephrine; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vasodilation

2004
Peroxisome proliferators-activated alpha agonist treatment ameliorates hepatic damage in rats with obstructive jaundice: an experimental study.
    BMC gastroenterology, 2007, Nov-28, Volume: 7

    Topics: Animals; Apoptosis; Bile Ducts; Bilirubin; Cholestasis; Cytokines; Fenofibrate; Hepatocytes; Inflammation Mediators; Jaundice, Obstructive; Ligation; Liver; Male; Malondialdehyde; PPAR alpha; Rats; Rats, Wistar

2007
Establishment of a methodology for investigating protectants against ethanol-induced hepatotoxicity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:5

    Topics: Animals; Antioxidants; Cell Culture Techniques; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chemoprevention; Ethanol; Fenofibrate; Hepatocytes; Hypolipidemic Agents; Male; Malondialdehyde; Nanoparticles; Nanotechnology; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Silybin; Silybum marianum; Silymarin

2010
Protective effect of berberine on antioxidant enzymes and positive transcription elongation factor b expression in diabetic rat liver.
    Fitoterapia, 2011, Volume: 82, Issue:2

    Topics: Animals; Antioxidants; Berberine; Coptis; Cyclin T; Cyclin-Dependent Kinase 9; Diabetes Mellitus, Experimental; Diet; Drugs, Chinese Herbal; Enzymes; Fenofibrate; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phytotherapy; Positive Transcriptional Elongation Factor B; Rats; Rats, Wistar; Rhizome; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Up-Regulation

2011
Effect of preischemic treatment with fenofibrate, a peroxisome proliferator-activated receptor-α ligand, on hepatic ischemia-reperfusion injury in rats.
    Journal of molecular histology, 2011, Volume: 42, Issue:2

    Topics: Alanine Transaminase; Animals; Endothelium; Fenofibrate; Hepatic Stellate Cells; Hepatocytes; Ischemia; Kupffer Cells; Liver; Male; Malondialdehyde; PPAR alpha; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2011
[A dyslipidemia animal model induced by poloxamer 407 in golden hamsters and pilot study on the mechanism].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:4

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; CD36 Antigens; Cricetinae; Disease Models, Animal; Dyslipidemias; Fenofibrate; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipid Metabolism; Liver; Male; Malondialdehyde; Mesocricetus; Nitric Oxide; Phosphatidylcholine-Sterol O-Acyltransferase; Poloxamer; PPAR alpha; Pyrroles; RNA, Messenger; Superoxide Dismutase

2011
Long-term fenofibrate treatment impaired glucose-stimulated insulin secretion and up-regulated pancreatic NF-kappa B and iNOS expression in monosodium glutamate-induced obese rats: is that a latent disadvantage?
    Journal of translational medicine, 2011, Oct-14, Volume: 9

    Topics: Adenosine Triphosphatases; Animals; Blood Glucose; Dyslipidemias; Fenofibrate; Glucose; Homeostasis; Insulin; Insulin Secretion; Malondialdehyde; Mitochondria; NF-kappa B; Nitric Oxide Synthase Type II; Obesity; Pancreas; Protein Transport; Rats; Rats, Wistar; Sodium Glutamate; Time Factors; Up-Regulation

2011
PPAR-alpha agonist treatment increases trefoil factor family-3 expression and attenuates apoptosis in the liver tissue of bile duct-ligated rats.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2013, Volume: 24, Issue:2

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Apoptosis; Aspartate Aminotransferases; Bile Ducts; Bilirubin; Fenofibrate; gamma-Glutamyltransferase; Hypolipidemic Agents; Interleukin-1beta; Ligation; Lipid Peroxidation; Liver; Male; Malondialdehyde; Neuropeptides; PPAR alpha; Rats; Rats, Wistar; RNA, Messenger; Trefoil Factor-3; Tumor Necrosis Factor-alpha

2013
Fenofibrate A peroxisome proliferator activated receptor-α agonist treatment ameliorates Concanavalin A-induced hepatitis in rats.
    European journal of pharmacology, 2013, Dec-05, Volume: 721, Issue:1-3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Concanavalin A; Fenofibrate; Hepatitis; Liver; Male; Malondialdehyde; Oxidative Stress; Portal Pressure; PPAR alpha; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2013
Ursodeoxycholic acid ameliorates fructose-induced metabolic syndrome in rats.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Fenofibrate; Fructose; Glutathione; Glycation End Products, Advanced; Insulin; Insulin Resistance; Male; Malondialdehyde; Metabolic Syndrome; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Triglycerides; Uric Acid; Ursodeoxycholic Acid

2014
Pleiotropic effects of fenofibrate therapy on rats with hypertriglycemia.
    Lipids in health and disease, 2015, Apr-14, Volume: 14

    Topics: Animals; Apolipoprotein A-I; Arginine; C-Reactive Protein; Cardiotonic Agents; Cholesterol, HDL; Dose-Response Relationship, Drug; Fenofibrate; Hypertriglyceridemia; Hypolipidemic Agents; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Sprague-Dawley; Triglycerides

2015
PPARα/γ agonists and antagonists differently affect hepatic lipid metabolism, oxidative stress and inflammatory cytokine production in steatohepatitic rats.
    Cytokine, 2015, Volume: 75, Issue:1

    Topics: Anilides; Animals; Chemokine CCL2; Cytokines; Disease Models, Animal; Fatty Acids, Nonesterified; Fenofibrate; Gene Expression Regulation; Glutathione; Indoles; Inflammation; Interleukin-6; Interleukin-8; Lipid Metabolism; Liver; Male; Malondialdehyde; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidative Stress; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones; Tumor Necrosis Factor-alpha

2015
Fenofibrate, a PPARα agonist, protect proximal tubular cells from albumin-bound fatty acids induced apoptosis via the activation of NF-kB.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:9

    Topics: Apoptosis; Cell Line; Cell Proliferation; Cell Survival; Chemokine CCL2; Cytoprotection; Dose-Response Relationship, Drug; Fatty Acids; Fenofibrate; Humans; Interleukin-8; Kidney Tubules, Proximal; Malondialdehyde; NF-kappa B; Oxidative Stress; PPAR alpha; Protein Binding; Serum Albumin, Bovine; Signal Transduction; Superoxide Dismutase; Transcription, Genetic; Transcriptional Activation; Up-Regulation

2015
Effects of combined PPAR-γ and PPAR-α agonist therapy on fructose induced NASH in rats: Modulation of gene expression.
    European journal of pharmacology, 2016, Feb-15, Volume: 773

    Topics: Adiponectin; Adipose Tissue; Animals; Blood Glucose; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Fenofibrate; Fructose; Gene Expression Regulation; Glutathione; Homeostasis; Insulin; Leptin; Liver; Male; Malondialdehyde; Non-alcoholic Fatty Liver Disease; Pioglitazone; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Thiazolidinediones; Triglycerides; Tumor Necrosis Factor-alpha

2016
Upregulation of peroxisome proliferator activated receptor alpha by fenofibrate in induced testicular ischemia reperfusion.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 98

    Topics: Animals; Apoptosis; Fenofibrate; Glutathione; Ischemia; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; PPAR alpha; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Testis; Transcriptional Activation; Tumor Necrosis Factor-alpha; Up-Regulation

2018
PPAR-α Agonist Improves Hyperglycemia-Induced Oxidative Stress in Pancreatic Cells by Potentiating Antioxidant Defense System.
    Drug research, 2018, Volume: 68, Issue:6

    Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Fenofibrate; Glutathione; Hyperglycemia; Male; Malondialdehyde; Nitrates; Oxidative Stress; Pancreas; PPAR alpha; Rats; Superoxide Dismutase

2018
Role of PPAR-α agonist fenofibrate in the treatment of induced benign prostatic hyperplasia with dysplastic changes in rats.
    Fundamental & clinical pharmacology, 2018, Volume: 32, Issue:6

    Topics: Animals; Antioxidants; Dihydrotestosterone; Fenofibrate; Glutathione Peroxidase; Male; Malondialdehyde; PPAR alpha; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Rats; Rats, Wistar; Superoxide Dismutase; Testosterone

2018
The protective effect of fenofibrate, triptorelin, and their combination against premature ovarian failure in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:1

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Combinations; Drug Therapy, Combination; Female; Fenofibrate; Glutathione; Hormones; Interleukin-10; Malondialdehyde; Nitrites; Ovary; Oxidative Stress; Primary Ovarian Insufficiency; Protective Agents; Rats, Wistar; Superoxide Dismutase; Triptorelin Pamoate; Tumor Necrosis Factor-alpha

2021
The IL-6/STAT Signaling Pathway and PPARα Are Involved in Mediating the Dose-Dependent Cardioprotective Effects of Fenofibrate in 5-Fluorouracil-Induced Cardiotoxicity.
    Cardiovascular drugs and therapy, 2022, Volume: 36, Issue:5

    Topics: Antioxidants; Cardiotoxicity; Caspase 3; Fenofibrate; Fluorouracil; Glutathione; Humans; Interleukin-6; Malondialdehyde; Oxidative Stress; PPAR alpha; Signal Transduction; STAT4 Transcription Factor

2022
The effects of simvastatin and fenofibrate on malondialdehyde and reduced glutathione concentrations in the plasma, liver, and brain of normolipidaemic and hyperlipidaemic rats.
    Arhiv za higijenu rada i toksikologiju, 2023, Mar-01, Volume: 74, Issue:1

    Topics: Animals; Antioxidants; Brain; Fenofibrate; Glutathione; Liver; Male; Malondialdehyde; Rats; Rats, Wistar; Rats, Zucker; Simvastatin

2023