Page last updated: 2024-08-21

malondialdehyde and edaravone

malondialdehyde has been researched along with edaravone in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (29.17)29.6817
2010's30 (62.50)24.3611
2020's4 (8.33)2.80

Authors

AuthorsStudies
Fung, KP; Wu, J; Wu, TW; Zeng, LH1
Andoh, A; Araki, Y; Asano, N; Bamba, S; Fujiyama, Y; Ishizuka, I; Yokono, T; Yoshikawa, K1
Andoh, A; Araki, Y; Fujiyama, Y1
Horikawa, S; Ito, K; Ozasa, H1
Horinaka, S; Matsuoka, H; Yagi, H1
Fujita, M; Furukawa, H; Jin, MB; Nakayama, M; Shimamura, T; Suzuki, T; Tahara, M; Taniguchi, M; Todo, S1
H S, AK; Patel, RJ; Saini, AK; Sharma, SS1
Ding, XS; Wang, W; Wu, J; Wu, T1
Koizumi, T; Sakaki, S; Shimazaki, S; Tanaka, H1
Huang, HY; Xu, QP; Zhang, G1
Gong, YY; Gu, Q; Li, CH; Song, Y; Wu, XW; Xie, ZG1
Ding, SJ; Han, N; Wu, T; Zhu, YL1
Kazuyama, E; Kinoshita, Y; Saito, M; Satoh, I; Satoh, K; Shimizu, S; Tamamura, M1
Ding, XS; Gao, Y; Kuai, F; Wang, W; Xu, S; Zuo, QL1
Kadokami, T; Maeda, T; Makino, N; Oyama, J; Satoh, S; Suematsu, N; Sugano, M1
Li, Y; Xia, AZ; Xing, SH1
Dimitriadis, F; Inoue, S; Kinoshita, Y; Ohmasa, F; Saito, M; Satoh, K; Shimizu, S; Shomori, K; Tsounapi, P1
Herlambang, B; Hiyama, E; Mizukami, T; Orihashi, K; Sueda, T; Takahashi, S; Uchida, N1
Bao, R; Chen, H; Deng, X; Hou, J; Li, J; Liu, Y; Sun, L; Wang, J; Yang, T; Zhang, J; Zhu, X1
Dimitriadis, F; Koukos, S; Saito, M; Satoh, K; Shimizu, S; Sofikitis, N; Takenaka, A; Tsounapi, P1
Cai, Z; Li, R; Liu, S; Ni, X; Quock, RM; Sun, X; Xu, W; Zhang, R1
Ding, XS; Gu, XS; Han, Q; Huang, H; Huang, HF; Liu, XF; Shen, LH; Wu, EB; Ye, M; Zhang, C1
Bu, N; Du, Y; Guo, YY; Li, TT; Liu, E; Sun, H; Wu, HQ; Yao, L; Zhang, GL; Zhang, L; Zhang, R; Zhang, WG1
Akdemir, A; Aktuğ, H; Erbaş, O; Ergenoglu, M; Oltulu, F; Taskiran, D; Yeniel, AÖ; Yildirim, N1
Li, M; Liu, X; Shao, R; Yang, G1
Alev, B; Emekli-Alturfan, E; Koc-Ozturk, L; Oktay, S; Tunali, S; Tunali-Akbay, T; Yanardag, R; Yarat, A1
Goto, T; Kurahashi, K; Ota, S; Tojo, K; Uchiyama, M; Yazawa, T1
Benetti, E; Chegaev, K; Chiazza, F; Collino, M; Cutrin, JC; Fruttero, R; Lazzarato, L; Rogazzo, M1
Alev, B; Emekli-Alturfan, E; Oktay, S; Ozturk, LK; Tunali, S; Tunali-Akbay, T; Yanardag, R; Yarat, A1
Chen, H; Hou, S; Zhang, S1
Liu, L; Song, Y; Yi, Z; Zeng, Q; Zhao, M1
Chen, X; Chen, Y; Lu, Z; Wang, S; Xu, W1
Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK1
Kou, Y; Tan, X; Wang, H; Xie, B; Zhang, J; Zhang, M1
Cao, J; Liu, N; Ma, L; Wang, P; Wang, Y; Zhang, H; Zhou, X1
Altun, İK; Alver, A; Arslan, FC; Gedikli, Ö; İnce, İ; Özkorumak, E; Tiryaki, A; Yıldırım, M1
Ge, X; Li, W; Li, X; Liang, X; Lu, F; Qin, L; Yao, Y; Yu, Q; Zhang, J; Zhao, D1
Kang, SS; Wu, R; Zhang, DY; Zhang, ZW1
Dimitriadis, F; Hikita, K; Honda, M; Saito, M; Shimizu, S; Shiomi, T; Sofikitis, N; Takenaka, A; Tomita, S; Tsounapi, P1
Chen, JJ; Fu, JL; Huang, JK; Wang, HM; Xiang, JY; Zhang, T; Zhao, YW1
Dong, Y; Liu, Z; Lv, P; Qi, Q; Teng, Z; Xiao, Y; Zhang, D1
Li, GP; Li, L; Liu, Q; Wang, ZZ; Xiao, W; Xu, ZL; Yang, H; Zhou, J; Zong, SB1
Ai, L; Bei, Y; He, W; Shou, L; Song, Y; Wang, L; Yan, Q1
Hu, L; Wan, YJ; Wang, XM1
Chen, WT; Sun, L; Wu, YM; Yang, YL; Zhang, NN1
Kara, O; Kaymak, E; Yakan, B1
Du, G; Gao, M; Shi, L; Song, J; Yang, H; Yu, X; Zhang, H; Zhang, W; Zhao, R1
Che, F; Ding, Q; Li, P; Su, D; Tang, B; Wang, X; Wu, W; Zhang, R; Zhang, W1

Trials

1 trial(s) available for malondialdehyde and edaravone

ArticleYear
Effects of edaravone on postoperative cognitive function in elderly patients undergoing hip joint replacement surgery: A randomized controlled trial.
    International journal of surgery (London, England), 2020, Volume: 80

    Topics: Aged; Arthroplasty, Replacement, Hip; Cognition; Cognition Disorders; Edaravone; Female; Humans; Interleukin-6; Male; Malondialdehyde; Matrix Metalloproteinase 9; Neuroprotective Agents; Postoperative Complications; Postoperative Period; S100 Calcium Binding Protein beta Subunit; Superoxide Dismutase; Treatment Outcome

2020

Other Studies

47 other study(ies) available for malondialdehyde and edaravone

ArticleYear
Myocardial protection of MCI-186 in rabbit ischemia-reperfusion.
    Life sciences, 2002, Sep-27, Volume: 71, Issue:19

    Topics: Animals; Antipyrine; Blood Pressure; Disease Models, Animal; Edaravone; Electrocardiography; Free Radical Scavengers; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Necrosis; Rabbits

2002
The free radical scavenger edaravone suppresses experimental closed duodenal loop-induced acute pancreatitis in rats.
    International journal of molecular medicine, 2003, Volume: 12, Issue:1

    Topics: Aldehydes; Amylases; Animals; Antipyrine; Ascitic Fluid; Edaravone; Free Radical Scavengers; Malondialdehyde; Pancreatitis, Acute Necrotizing; Rats

2003
The free radical scavenger edaravone suppresses experimental dextran sulfate sodium-induced colitis in rats.
    International journal of molecular medicine, 2003, Volume: 12, Issue:1

    Topics: Aldehydes; Animals; Antipyrine; Colitis; Edaravone; Free Radical Scavengers; Interleukin-6; Male; Malondialdehyde; Peroxidase; Rats; Rats, Sprague-Dawley

2003
Edaravone protects against lung injury induced by intestinal ischemia/reperfusion in rat.
    Free radical biology & medicine, 2005, Feb-01, Volume: 38, Issue:3

    Topics: Animals; Antipyrine; Disease Progression; Edaravone; Interleukin-6; Intestines; Ischemia; Lung; Male; Malondialdehyde; Neutrophil Infiltration; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; RNA, Messenger; Survival Analysis

2005
Edaravone prevented deteriorated cardiac function after myocardial ischemia-reperfusion via inhibiting lipid peroxidation in rat.
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:1

    Topics: Animals; Antipyrine; Edaravone; Free Radical Scavengers; Heart; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Contraction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Tachycardia, Ventricular; Ventricular Pressure

2005
A radical scavenger, edaravone, protects canine kidneys from ischemia-reperfusion injury after 72 hours of cold preservation and autotransplantation.
    Transplantation, 2005, Jul-27, Volume: 80, Issue:2

    Topics: Animals; Antipyrine; Dogs; Edaravone; Female; Free Radical Scavengers; Kidney; Kidney Function Tests; Kidney Transplantation; Malondialdehyde; Organ Preservation; P-Selectin; Reperfusion Injury; Transplantation, Autologous

2005
Edaravone attenuates hydroxyl radical stress and augmented angiotensin II response in diabetic rats.
    Pharmacological research, 2006, Volume: 54, Issue:1

    Topics: Angiotensin II; Animals; Antipyrine; Aorta, Thoracic; Blood Pressure; Catalase; Diabetes Mellitus, Experimental; Edaravone; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; tert-Butylhydroperoxide; Vasoconstriction

2006
MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one) attenuated simulated ischemia/reperfusion injury in cultured rat hippocampal cells.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:8

    Topics: Animals; Antipyrine; Apoptosis; Calcium; Cells, Cultured; Edaravone; Hippocampus; Malondialdehyde; Membrane Potentials; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2006
The therapeutic efficacy of edaravone in extensively burned rats.
    Archives of surgery (Chicago, Ill. : 1960), 2006, Volume: 141, Issue:10

    Topics: Animals; Antipyrine; Burns; Disease Models, Animal; Edaravone; Free Radical Scavengers; Free Radicals; Lung; Male; Malondialdehyde; Prospective Studies; Random Allocation; Rats; Rats, Wistar; Xanthine Oxidase

2006
[Protective effects of edaravone on renal ischemia-reperfusion injury in rats].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2008, Volume: 37, Issue:3

    Topics: Animals; Antipyrine; Edaravone; Kidney; Male; Malondialdehyde; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase

2008
Edaravone (MCI-186), a free radical scavenger, attenuates retinal ischemia/reperfusion injury in rats.
    Acta pharmacologica Sinica, 2008, Volume: 29, Issue:7

    Topics: Animals; Antipyrine; Apoptosis; Edaravone; Electroretinography; Free Radical Scavengers; In Situ Nick-End Labeling; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Retinal Diseases; Superoxide Dismutase

2008
Correlation of free radical level and apoptosis after intracerebral hemorrhage in rats.
    Neuroscience bulletin, 2008, Volume: 24, Issue:6

    Topics: Analysis of Variance; Animals; Antipyrine; Apoptosis; Cerebral Hemorrhage; Disease Models, Animal; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Hydroxyl Radical; In Situ Nick-End Labeling; Linear Models; Male; Malondialdehyde; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors

2008
Acute urinary retention and subsequent catheterization cause lipid peroxidation and oxidative DNA damage in the bladder: preventive effect of edaravone, a free-radical scavenger.
    BJU international, 2009, Volume: 104, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Animals; Antipyrine; Deoxyguanosine; DNA Damage; Edaravone; Free Radical Scavengers; HSP70 Heat-Shock Proteins; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Urinary Bladder Diseases; Urinary Catheterization; Urinary Retention

2009
Neuroprotective effects of edaravone on early brain injury in rats after subarachnoid hemorrhage.
    Chinese medical journal, 2009, Aug-20, Volume: 122, Issue:16

    Topics: Animals; Antipyrine; Blotting, Western; Brain Injuries; Edaravone; Immunohistochemistry; Male; Malondialdehyde; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Superoxide Dismutase

2009
Scavenging free radicals improves endothelial dysfunction in human coronary arteries in vivo.
    Heart and vessels, 2010, Volume: 25, Issue:5

    Topics: Acetylcholine; Aged; Aldehydes; Antipyrine; Blood Flow Velocity; Coronary Angiography; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Echocardiography, Doppler; Edaravone; Endothelium, Vascular; Female; Free Radical Scavengers; Free Radicals; Humans; Infusions, Intra-Arterial; Isosorbide Dinitrate; Japan; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Vasodilation; Vasodilator Agents

2010
Protective effect of edaravone against renal ischemia/reperfusion injury and compared with ischemic postconditioning in rats.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:7

    Topics: Animals; Antipyrine; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Creatinine; Edaravone; Free Radical Scavengers; Ischemic Postconditioning; Kidney; Male; Malondialdehyde; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase

2010
Edaravone ameliorates diabetes-induced dysfunction of NO-induced relaxation in corpus cavernosum smooth muscle in the rat.
    The journal of sexual medicine, 2011, Volume: 8, Issue:6

    Topics: Animals; Antipyrine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Edaravone; Free Radical Scavengers; Impotence, Vasculogenic; Male; Malondialdehyde; Muscle, Smooth, Vascular; Nitric Oxide; Penis; Rats; Rats, Wistar; Reactive Oxygen Species; Vasodilation

2011
New method for absolute spinal cord ischemia protection in rabbits.
    Journal of vascular surgery, 2011, Volume: 54, Issue:4

    Topics: Animals; Antipyrine; Aorta; Biomarkers; Combined Modality Therapy; Constriction; Disease Models, Animal; Edaravone; Free Radical Scavengers; Hypothermia, Induced; Infusions, Intra-Arterial; Malondialdehyde; Motor Neurons; Neurologic Examination; Neuroprotective Agents; Oxidative Stress; Paraplegia; Rabbits; Reperfusion Injury; Severity of Illness Index; Spinal Cord Ischemia; Time Factors; Vascular Surgical Procedures

2011
Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012, Volume: 61, Issue:6

    Topics: Acute Lung Injury; Animals; Antipyrine; Drug Combinations; Edaravone; Free Radical Scavengers; Glycine; Interleukin-6; Lipopolysaccharides; Male; Malondialdehyde; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Rats; Rats, Sprague-Dawley; Sulfonamides; Tumor Necrosis Factor-alpha

2012
Antioxidant treatment with edaravone or taurine ameliorates diabetes-induced testicular dysfunction in the rat.
    Molecular and cellular biochemistry, 2012, Volume: 369, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Antipyrine; Deoxyguanosine; Diabetes Complications; Diabetes Mellitus, Experimental; DNA Fragmentation; Edaravone; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Taurine; Testicular Diseases; Testis

2012
Perfluorocarbon-facilitated CNS oxygen toxicity in rats: reversal by edaravone.
    Brain research, 2012, Aug-30, Volume: 1471

    Topics: Animals; Antipyrine; Brain; Catalase; Disease Models, Animal; Drug Synergism; Edaravone; Electroencephalography; Fluorocarbons; Free Radical Scavengers; Glutathione Peroxidase; Hydrogen Peroxide; Male; Malondialdehyde; Neurotoxicity Syndromes; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors

2012
Protective effects of MCI-186 on transplantation of bone marrow stromal cells in rat ischemic stroke model.
    Neuroscience, 2012, Oct-25, Volume: 223

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antipyrine; Brain; Brain Infarction; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Disease Models, Animal; Edaravone; Flow Cytometry; Free Radical Scavengers; Glucose; Hypoxia; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Malondialdehyde; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neurologic Examination; Neurons; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Time Factors; Vascular Endothelial Growth Factor A

2012
Edaravone ameliorates oxidative damage associated with Aβ25-35 treatment in PC12 cells.
    Journal of molecular neuroscience : MN, 2013, Volume: 50, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Antipyrine; Apoptosis; Cell Survival; Edaravone; Free Radical Scavengers; Glutathione; Lipid Peroxidation; Malondialdehyde; Mitochondria; Oxidative Stress; PC12 Cells; Peptide Fragments; Rats; Reactive Oxygen Species; Superoxide Dismutase

2013
Attenuation of ischemia/reperfusion-induced ovarian damage in rats: does edaravone offer protection?
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2013, Volume: 51, Issue:1-2

    Topics: Animals; Antipyrine; Caspase 3; Edaravone; Female; Free Radical Scavengers; Glutathione; Immunohistochemistry; Malondialdehyde; Ovary; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2013
Edaravone protects neurons in the rat substantia nigra against 6-hydroxydopamine-induced oxidative stress damage.
    Cell biochemistry and biophysics, 2014, Volume: 70, Issue:2

    Topics: Animals; Antipyrine; Behavior, Animal; Corpus Striatum; Edaravone; Glutathione; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra

2014
Edaravone ameliorates the adverse effects of valproic acid toxicity in small intestine.
    Human & experimental toxicology, 2015, Volume: 34, Issue:6

    Topics: Alkaline Phosphatase; Animals; Antipyrine; Edaravone; Female; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Intestine, Small; Malondialdehyde; N-Acetylneuraminic Acid; Peroxidase; Rats, Sprague-Dawley; Superoxide Dismutase; Thromboplastin; Valproic Acid

2015
Edaravone prevents lung injury induced by hepatic ischemia-reperfusion.
    The Journal of surgical research, 2015, Volume: 194, Issue:2

    Topics: Acute Lung Injury; Alanine Transaminase; Animals; Antipyrine; Aspartate Aminotransferases; Cytokines; Drug Evaluation, Preclinical; Edaravone; Free Radical Scavengers; Liver; Lung; Male; Malondialdehyde; Random Allocation; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury

2015
A nitric oxide-donor furoxan moiety improves the efficacy of edaravone against early renal dysfunction and injury evoked by ischemia/reperfusion.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Acetylglucosamine; Acute-Phase Proteins; Animals; Antipyrine; Creatinine; Disease Models, Animal; Edaravone; Free Radical Scavengers; Ischemia; Kidney; Lipid Peroxidation; Lipocalin-2; Lipocalins; Male; Malondialdehyde; Nitric Oxide Donors; Oxadiazoles; Oxidative Stress; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reperfusion Injury; Urea

2015
Effects of edaravone on cardiac damage in valproic acid induced toxicity.
    Annals of clinical and laboratory science, 2015,Spring, Volume: 45, Issue:2

    Topics: Alkaline Phosphatase; Animals; Antipyrine; Catalase; Edaravone; Female; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Lipid Peroxidation; Malondialdehyde; Myocardium; N-Acetylneuraminic Acid; Peroxidase; Rats; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Thromboplastin; Valproic Acid

2015
[Protective effect of novel edaravone and danshensu conjugate on focal cerebral ischemia-reperfusion injury 
in rats and its underlying mechanism].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2015, Volume: 40, Issue:6

    Topics: Animals; Antipyrine; Brain Edema; Brain Ischemia; Cerebral Infarction; Edaravone; Lactates; Malondialdehyde; Rats; Reperfusion Injury; Superoxide Dismutase

2015
Protective effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced acute kidney injury in a rat model of sepsis.
    International urology and nephrology, 2015, Volume: 47, Issue:10

    Topics: Acute Kidney Injury; Animals; Antipyrine; Apoptosis; Blood Urea Nitrogen; Catalase; Cells, Cultured; Disease Models, Animal; Edaravone; Free Radical Scavengers; Glutathione; Interleukin-6; Kidney Tubules; Lipopolysaccharides; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Dynamics; Oxidative Stress; Rats; Rats, Wistar; Sepsis; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2015
[Effect of edaravone on oxidative stress and myocardial fibrosis induced by isoproterenol in rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2015, Volume: 35, Issue:11

    Topics: Animals; Antipyrine; Cardiomyopathies; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Edaravone; Heart; Hydroxyproline; Isoproterenol; Male; Malondialdehyde; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta1

2015
Edaravone, a potent free radical scavenger and a calcium channel blocker attenuate isoproterenol induced myocardial infarction by suppressing oxidative stress, apoptotic signaling and ultrastructural damage.
    Therapeutic advances in cardiovascular disease, 2016, Volume: 10, Issue:4

    Topics: Animals; Antipyrine; Apoptosis; C-Reactive Protein; Calcium Channel Blockers; Caspase 3; Dihydropyridines; Edaravone; Female; Free Radical Scavengers; Isoproterenol; Male; Malondialdehyde; Myocardial Infarction; Myocardium; Oxidative Stress; Rats; Rats, Wistar

2016
[The pulmonary injury in rats caused by chronic intermittent hypoxia and the intervention effect of Edaravone].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2015, Volume: 29, Issue:19

    Topics: Angiotensin II; Animals; Antipyrine; Edaravone; Free Radical Scavengers; Hypoxia; Lung; Lung Injury; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase

2015
Protective Effects of Edaravone in Adult Rats with Surgery and Lipopolysaccharide Administration-Induced Cognitive Function Impairment.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Animals; Antipyrine; Brain; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Edaravone; Free Radical Scavengers; Humans; Inflammation Mediators; Lipopolysaccharides; Male; Malondialdehyde; Nephrectomy; Neuroprotective Agents; Oxidative Stress; Postoperative Complications; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; TOR Serine-Threonine Kinases

2016
The effects of edaravone in ketamine-induced model of mania in rats.
    Acta neurobiologiae experimentalis, 2016, Volume: 76, Issue:3

    Topics: Analysis of Variance; Animals; Antimanic Agents; Antipyrine; Bipolar Disorder; Brain; Catalase; Disease Models, Animal; Drug Administration Schedule; Edaravone; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Ketamine; Lithium Chloride; Locomotion; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2016
Edaravone injection reverses learning and memory deficits in a rat model of vascular dementia.
    Acta biochimica et biophysica Sinica, 2017, Volume: 49, Issue:1

    Topics: Animals; Antipyrine; Dementia, Vascular; Disease Models, Animal; Edaravone; Fear; L-Lactate Dehydrogenase; Learning Disabilities; Male; Malondialdehyde; Memory Disorders; Rats; Rats, Wistar; Superoxide Dismutase

2017
Edaravone enhances the viability of ischemia/reperfusion flaps.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2017, Volume: 37, Issue:1

    Topics: Animals; Antipyrine; Disease Models, Animal; Edaravone; Graft Survival; Ischemic Preconditioning; Male; Malondialdehyde; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Surgical Flaps

2017
Antioxidant treatment ameliorates diabetes-induced dysfunction of the vas deferens in a rat model.
    Andrologia, 2018, Volume: 50, Issue:1

    Topics: Animals; Antioxidants; Antipyrine; Diabetes Mellitus, Experimental; Edaravone; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Taurine; Vas Deferens

2018
Edaravone Attenuates the Proinflammatory Response in Amyloid-β-Treated Microglia by Inhibiting NLRP3 Inflammasome-Mediated IL-1β Secretion.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 43, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Antipyrine; Caspase 1; CD11b Antigen; Cell Survival; Cells, Cultured; Edaravone; Inflammasomes; Interleukin-1beta; Lipopolysaccharides; Malondialdehyde; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Microglia; Mitochondria; Neurons; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase

2017
Edaravone attenuates oxidative stress induced by chronic cerebral hypoperfusion injury: role of ERK/Nrf2/HO-1 signaling pathway.
    Neurological research, 2018, Volume: 40, Issue:1

    Topics: Animals; Antipyrine; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Heme Oxygenase-1; Hippocampus; Male; Malondialdehyde; MAP Kinase Signaling System; Maze Learning; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Superoxide Dismutase

2018
Diterpene ginkgolides meglumine injection protects against paraquat-induced lung injury and pulmonary fibrosis in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Acute Lung Injury; Animals; Antipyrine; Dose-Response Relationship, Drug; Edaravone; Ginkgolides; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Meglumine; Pulmonary Edema; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2018
Nrf2 mediates the protective effect of edaravone after chlorpyrifos-induced nervous system toxicity.
    Environmental toxicology, 2019, Volume: 34, Issue:5

    Topics: Animals; Apoptosis; Cell Survival; Chlorpyrifos; Edaravone; Malondialdehyde; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase

2019
Edaravone protects from retinal injury through NF-κB in diabetic rats.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:3 Suppl

    Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Edaravone; Interleukin-6; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Treatment Outcome; Tumor Necrosis Factor-alpha

2019
Protective effect of edaravone on cisplatin-induced injury in rat ovary.
    Archives of gynecology and obstetrics, 2022, Volume: 306, Issue:5

    Topics: Animals; Antipyrine; Apoptosis; Caspase 3; Caspase 8; Cisplatin; Edaravone; Female; Malondialdehyde; Nitric Oxide; Ovary; Rats; Rats, Wistar

2022
Edaravone Dexborneol Alleviates Cerebral Ischemic Injury via MKP-1-Mediated Inhibition of MAPKs and Activation of Nrf2.
    BioMed research international, 2022, Volume: 2022

    Topics: Animals; Brain Injuries; Dual Specificity Phosphatase 1; Edaravone; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Malondialdehyde; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Peroxidase; Rats

2022
A new multi-parameter imaging platform for in vivo drug efficacy evaluation of ischemic stroke.
    Talanta, 2024, Jan-01, Volume: 266, Issue:Pt 2

    Topics: Edaravone; Formaldehyde; Humans; Ischemic Stroke; Malondialdehyde; Optical Imaging

2024