malondialdehyde has been researched along with beta-escin in 134 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.75) | 18.7374 |
| 1990's | 14 (10.45) | 18.2507 |
| 2000's | 30 (22.39) | 29.6817 |
| 2010's | 76 (56.72) | 24.3611 |
| 2020's | 13 (9.70) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, XM; Zeng, FD | 1 |
| Akkol, EK; Avci, G; Bacak, E; Ince, S; Keleş, H; Küçükkurt, I; Yeşilada, E | 1 |
| Bao-ming, G; Bin, Z; Hong-fang, J; Jun-bao, D; Li, N; Qiang, X; Tian-shui, L; Tong, W; Wei, T; Wen-ping, S; Xiao-hui, D; Zhi-fang, C | 1 |
| Buzzacott, P; Jiang, Z; Ning, X; Xu, J; Xu, W; Yu, X; Zhang, K | 1 |
| Kulkarni, YA; Suryavanshi, SV | 1 |
| Ding, Y; Huang, DK; Shen, JP; Zhang, XL; Zhang, YD; Zhu, SH | 1 |
| Deng, HL; Zhang, JT | 1 |
| Chen, X; Qiu, FL; Shen, N; Xiong, WS; Yan, XD | 1 |
| Chen, X; Chu, GX | 1 |
| Chen, JX; Li, X; Sun, JJ | 1 |
| Chen, X; Deng, HW; Li, DY; Li, YJ; Shen, N; Yang, BC | 1 |
| Bai, X; Ding, H; Huang, Z; Mo, Z; Pan, H | 1 |
| Bhattacharya, S; Ghosh, NK; Saha, A; Sarkar, D; Sinha Babu, SP; Sukul, NC | 1 |
| Dong, E; Liu, ZW; Yokozawa, T | 1 |
| Kim, SR; Kim, YC; Markelonis, GJ; Oh, TH | 1 |
| Jiang, C; Shen, W; Sun, Z; Tian, Y; Wang, D; Yuan, S | 1 |
| Chen, FM; Crowther, RS; He, BB; Huang, YS; Li, A; Liu, XS; Yang, ZC | 1 |
| Owada, S; Yokozawa, T | 1 |
| Fu, ZG; He, K; Wu, T; Yang, Y | 1 |
| Liu, ZW; Yokozawa, T | 1 |
| Izumi, T; Kataoka, S; Kikuchi, M; Obata, A; Piskula, MK; Saito, M; Tobe, K; Yamakoshi, J | 1 |
| Du, N; Li, L; Wang, X | 1 |
| Alvarez, AI; Cabral de Oliveira, AC; Merino, G; Perez, AC; Prieto, JG | 1 |
| Choi, J; Jung, GO; Lee, KT; Park, HJ; Park, KY | 1 |
| Chen, XL; Hu, HT; Liu, Y; Qian, YH; Ren, HM; Xu, JH | 1 |
| Fan, Y; Hu, ZB; Kong, JL; Wu, DZ; Zhou, JY | 1 |
| Chen, J; Ding, D; Fu, JH; Hong, Z; Luo, Y; Qin, Z; Zhang, WD; Zhang, X | 1 |
| Saxena, R; Sinha, S | 1 |
| Chen, XF; He, DL; Li, X; Luo, Y; Sheng, BW; Yu, LH; Zhang, LL | 1 |
| Cheng, XF; He, DL; Li, JJ; Li, X; Yu, LH; Zhang, LL | 1 |
| Chen, WH; Fang, JY; Liu, M; Lu, LG; Mao, YM; Xu, ZN; Zeng, MD | 1 |
| Ali, MB; Hahn, EJ; Paek, KY | 1 |
| Chen, J; Jiang, B; Lu, JY; Tang, C; Yuan, J | 1 |
| Arun, M; Asha, VV | 1 |
| Hao, R; Huang, QF; Liu, XM; Lou, JL; Zhang, J; Zhang, YL; Zheng, H | 1 |
| Cheng, YP; Gu, SY; Huang, QJ; Ji, H; Shao, Q; Xu, XL | 1 |
| Chen, HP; He, M; Huang, M; Huang, QR; Liu, D | 1 |
| Chen, H; Dai, Y; He, M; Huang, Q; Liu, D; Luo, Y; Shao, L | 1 |
| Li, H; Wang, QJ; Yang, Y; Zhu, DN | 1 |
| Qu, SC; Sui, DY; Wang, L; Xu, HL; Yu, XF | 1 |
| Li, WP; Li, WZ; Yin, YY | 1 |
| Chen, YW; Guo, JZ; He, Y; Hu, ZF; Li, KM; Li, P; Pan, L; Xiao, C; Xiong, JP | 1 |
| Baek, IS; Han, PL; Im, GJ; Kim, KS; Kim, TK; Lee, KW; Lee, SM; Leem, YH; Park, SK; Park, YH; Seo, JS | 1 |
| Kang, HS; Kim, CJ; Lee, JY; Moon, HJ; Park, BE; Sim, SS | 1 |
| Baek, S; Jang, S; Kim, S; Lee, M; Sorn, S | 1 |
| Fu, XJ; Guan, HS; Liu, HB; Wang, P | 1 |
| Kondeva-Burdina, MS; Krasteva, IN; Mitcheva, MK; Nikolov, SD; Simeonova, RL; Vitcheva, VB | 1 |
| Han, D; Qu, S; Sui, D; Wang, X; Xu, H; Yu, X | 1 |
| Kim, TH; Lee, SM | 1 |
| Aiyegoro, OA; Okoh, AI | 1 |
| Gong, HL; Li, WP; Li, WZ; Wu, GC; Yin, YY; Zhu, FF | 1 |
| Deng, ZJ; Fu, YH; Guo, JW; Li, LM; Liu, RX; Pan, JQ; Qiu, GQ; Yang, M | 1 |
| Feng, XC; Jiang, YZ; Lian, LH; Nan, JX; Wu, YL | 1 |
| Huang, W; Sun, R | 1 |
| Baek, IS; Cho, Y; Han, PL; Kim, TK; Lee, SM; Leem, YH; Park, YH; Seo, JS | 1 |
| Wen, DJ; Zhang, CL; Zhang, S | 1 |
| Ke, YS; Wang, DG; Wang, HG; Yang, SY | 1 |
| Gao, YQ; Huang, J; Huang, QY; Liao, WG; Luo, H | 1 |
| Wu, GC; Yin, YY; Zhu, FF | 1 |
| Li, H; Xu, H; Yang, SJ; Zhang, S | 1 |
| Li, MQ; Lu, Y; Ruan, JS; Wang, AY; Yan, LG; Zhang, L; Zheng, SZ | 1 |
| Mao, SL; Wang, XH; Zhang, N; Zhao, F | 1 |
| Chai, JD; Ji, KT; Tang, JF | 1 |
| Bi, CW; Bi, K; Chen, X; Choi, RC; Dong, TT; Li, J; Ran, W; Tsim, KW; Wang, T | 1 |
| He, M; Huang, Q; Huang, R; Lin, X; Zhang, S; Zheng, L | 1 |
| Li, J; Lu, J; Wan, H; Yang, J; Zhang, Y; Zhu, Z | 1 |
| He, H; He, Y; Wang, H; Wang, T; Xu, J; Xu, Y; Yuan, D; Zhang, C | 1 |
| Chen, X; Deng, Y; He, K; Huang, J; Jin, Q; Jin, Y; Li, P; Li, X; Ye, X; Yuan, L | 1 |
| Haji, AA; Kaiser, A; Li, X; Parhat, K; Wei, YY; Yan, D | 1 |
| Krasteva, I; Mitcheva, M; Nikolov, S; Simeonova, R; Vitcheva, V | 1 |
| Bian, D; Dai, Y; Gong, Z; Li, Y; Liu, M; Xia, Y | 1 |
| An, L; Wen, W; Wu, J; Yang, G; Yuan, J; Zhang, F; Zhu, W | 1 |
| Liu, XQ; Ouyang, LY; Wu, JW; Wu, MX; Zhang, JC; Zheng, GF | 1 |
| Chen, D; Chen, S; Fan, CL; Huang, JF; Liu, P; Shang, L; Wang, H; Xiong, K; Zhang, MQ | 1 |
| Liu, X; Shan, L; Wang, R; Yue, R; Zhang, J; Zhang, W | 1 |
| Di, GJ; He, HB; He, YM; Li, SC; Sun, ZW; Wang, HW; Xu, J; Xu, YQ; Yuan, D | 1 |
| Chen, Q; Cheng, GL; Xia, L | 1 |
| Li, Y; Liu, F; Liu, X; Shan, L; Wang, R; Wang, S; Yue, R; Zhang, J; Zhang, S; Zhang, W | 1 |
| Fang, W; Han, D; Li, Y; Liu, L; Sha, L; Wei, J; Zhang, R | 1 |
| Fan, W; Gao, W; Li, H; Li, Y; Liu, Z; Man, S; Wang, Y | 1 |
| Gou, X; He, WY; Li, H; Lin, F | 1 |
| Guo, Y; Hai, CX; Li, JG; Li, YN; Qin, XJ; Xi, MM; Yang, P; Yin, S; Zhou, XY | 1 |
| Liu, HZ; Liu, ZL; Sun, CZ; Yang, MS; Zhao, SP | 1 |
| Bian, Y; Gao, D; Li, N; Liu, Y; Liu, Z; Qi, X; Zhao, M | 1 |
| Fu, J; Guo, Q; Ji, H; Li, T; Liu, L; Tan, J; Zhang, Y | 1 |
| Cao, RF; Chen, JW; Cong, X; Cui, K; Gao, SS; Guo, XT; Jiang, ZL; Tian, WR; Zhang, BZ; Zhao, Y | 1 |
| Cai, J; Cao, W; Chen, J; Chu, X; Deng, H; Li, X; Liu, Z; Mao, L; Sun, S; Zha, L | 1 |
| Chen, J; Chu, X; Deng, H; Luo, H; Mao, L; Sun, S; Wu, J; Zha, D; Zha, L | 1 |
| Fu, D; Yang, F; Zhu, T | 1 |
| Jia, W; Jia, ZY; Wang, XY; Xie, X | 1 |
| Bao, JL; Cao, YW; Ding, RB; He, C; Hu, Y; Su, H; Tian, K; Wan, JB; Wang, M | 1 |
| Chen, Y; Hu, S; Wang, S; Xu, Y; Yu, J; Zhai, L; Zhang, L | 1 |
| Li, J; Liu, ZQ; Wang, JZ; Wang, T; Yang, L; Yuan, D; Zhang, CC | 1 |
| Chen, J; Hu, J; Ji, K; Li, J; Liao, L; Lu, Q; Song, X; Tang, J; Wang, G; Wang, X; Wu, W; Xue, Y; Yin, R | 1 |
| Dong, D; Peng, J; Qi, Y; Xu, L; Yin, L | 1 |
| Bai, X; Ding, RB; Hu, YJ; Liu, F; Su, H; Wan, JB | 1 |
| Fang, Y; Liu, Q; Xu, XH; Xue, Q; You, XY; Zhang, CF; Zhang, M; Zhao, C | 1 |
| Chai, H; Gao, W; Li, J; Liu, J; Liu, Z; Man, S; Wang, J | 1 |
| Chen, T; Ji, H; Jiang, W; Lu, G; Ma, Z; Ren, Y; Song, Y; Wang, H; Wang, R; Xu, A; Xu, Y; Yong, S | 1 |
| Chen, HB; Chen, HL; He, XC; Huang, H; Peng, WL; Tang, YN; Ye, M; Yi, T; Zhao, ZZ | 1 |
| Chai, KF; Du, YG; Qian, JW; Wang, LP; Zhang, KN | 1 |
| Li, J; Wang, T; Yang, L; Yuan, D; Zhang, CC | 1 |
| Li, J; Li, W; Liang, H; Mao, S; Yang, G; Zhang, J; Zhang, M | 1 |
| Guo, C; Li, F; Meng, Z; Shen, J; Yang, X | 1 |
| He, Q; Lei, F; Lei, X; Li, R; Tan, H | 1 |
| Gao, W; Guo, Y; Yang, H | 1 |
| Li, W; Li, YZ; Ma, ZN; Yan, XT; Yang, G; Yang, LM; Zhang, J; Zhao, LC | 1 |
| Chen, Q; Li, G; Wang, C; Wang, Y; Yu, J; Zhang, L | 1 |
| Chen, Y; Li, Y; Lin, L; Que, R; Shen, Y; Yan, N | 1 |
| Meng, XB; Sun, DM; Sun, GB; Sun, XB; Wang, MX; Zhao, JY | 1 |
| Chen, C; Fu, CL; Hu, JN; Jiang, S; Leng, J; Li, W; Ren, S; Wang, YP; Wang, Z; Zhang, J | 1 |
| Huang, L; Ji, C; Lu, Z; Luo, Y; Tian, R; Zou, C | 1 |
| Chen, C; Fu, CL; He, YF; Leng, J; Li, W; Liu, Y; Wang, Z; Zhang, J | 1 |
| Liu, X; Sun, G; Sun, X; Wang, M; Wang, R; Xu, H; Xu, X; Yang, M | 1 |
| Almeida, JD; Barbosa, MC; Ishii-Iwamoto, EL; Kagami, FL; Kern-Cardoso, KA; Mantovanelli, GC; Mito, MS; Silva, AA | 1 |
| Kan, P; Wang, J; Xiang, L; Xu, N; Yang, P; Yao, X; Zhu, Y | 1 |
| Hong, Y; Jin, H; Li, M; Mei, F; Wang, W; Xia, H; Xiang, M; You, Y; Yu, J; Zhou, Y | 1 |
| Cheng, X; Ge, D; Qi, B; Wang, S; Zhang, Z | 1 |
| Ma, Y; Xiong, L | 1 |
| Chen, X; Peng, X; Rao, X; Zheng, C; Zhu, Y | 1 |
| Bi, S; Chi, X; Hu, S; Shi, F; Wang, H; Wang, Y; Wang, Z; Zhang, Y | 1 |
| Gu, H; Guo, H; Hao, K; Jiang, W; Su, D; Xu, H | 1 |
| Deng, LL; Dun, YY; He, YM; Liu, CQ; Wan, JZ; Wang, R; Wang, T; Yuan, CF; Yuan, D; Zhang, CC; Zhao, HX; Zhou, ZY | 1 |
| Chen, D; Feng, Y; Guo, M; Ren, C; Shi, K; Wang, J; Wu, X; Zhu, J | 1 |
| Ren, D; Yang, C; Yang, X; Zhao, Y | 1 |
| Chen, Z; Cui, J; Fan, Z; Guo, B; Hu, J; Liu, Y; Shen, J; Wang, Y; Wu, Y; Xie, L | 1 |
| Chen, C; Gong, XJ; Hou, JG; Jiang, S; Leng, J; Li, W; Liu, W; Liu, Z; Wang, YP; Wang, Z | 1 |
| Song, L; Xing, B; Yang, S; Zhang, P; Zhang, R; Zhou, L | 1 |
| Liu, P; Mu, LH; Wang, LH; Wang, YN; Yan, C; Yan, H; Yu, TF | 1 |
| Chen, J; Hua, M; Li, Z; Sun, Y | 1 |
| Cheng, J; Fan, Y; Guo, D; Li, H; Shi, Y; Sun, J; Zhai, B; Zhang, X; Zou, J | 1 |
| Du, J; Huang, X; Li, B; Li, L; Li, Y; Liu, J; Song, D | 1 |
| Chen, L; Ma, H; Muge, Q; Wang, L; Zhou, Z | 1 |
| Fan, DD; Gao, HM; Li, M; Li, XW; Teng, F; Wang, ZM; Zhu, JJ | 1 |
1 trial(s) available for malondialdehyde and beta-escin
| Article | Year |
|---|---|
Antioxidative effect of ginseng stem-leaf saponins on oxidative stress induced by cyclophosphamide in chickens.
Topics: Animals; Antioxidants; Bursa of Fabricius; Catalase; Chickens; Cyclophosphamide; Glutathione Peroxidase; Immunosuppressive Agents; Malondialdehyde; Oxidative Stress; Panax; Plant Leaves; Plant Stems; Poultry Diseases; Protein Carbonylation; Saponins; Specific Pathogen-Free Organisms; Spleen; Superoxide Dismutase; Thymus Gland | 2015 |
133 other study(ies) available for malondialdehyde and beta-escin
| Article | Year |
|---|---|
Protective effects of sodium beta-aescin on ischemia-reperfusion injury in rat brain.
Topics: Animals; Brain; Brain Ischemia; Catalase; Escin; Glutathione Peroxidase; Male; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2004 |
Beneficial effects of Aesculus hippocastanum L. seed extract on the body's own antioxidant defense system on subacute administration.
Topics: Aesculus; Animals; Antioxidants; Catalase; Dietary Fats; Escin; Kidney; Liver; Male; Malondialdehyde; Mice; Myocardium; Oxidative Stress; Plant Extracts; Seeds; Superoxide Dismutase | 2010 |
The impact of sodium aescinate on acute lung injury induced by oleic acid in rats.
Topics: Acute Lung Injury; Animals; Arteries; Blood Gas Analysis; Escin; Male; Malondialdehyde; Matrix Metalloproteinase 9; Oleic Acid; Oxygen; Rats; Rats, Sprague-Dawley; Sodium Compounds; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-1 | 2011 |
Endothelia-Targeting Protection by Escin in Decompression Sickness Rats.
Topics: Animals; Antioxidants; Biomarkers; Decompression Sickness; Endothelial Cells; Escin; Inflammation; Male; Malondialdehyde; Protective Agents; Rats, Sprague-Dawley; Superoxide Dismutase | 2017 |
Attenuation of Cardiac Autonomic Neuropathy by Escin in Diabetic Rats.
Topics: Animals; Antioxidants; Autonomic Nervous System Diseases; Catalase; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Escin; Glutathione; Heart; Heart Diseases; Heart Rate; Hemodynamics; Male; Malondialdehyde; Matrix Metalloproteinase 9; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Superoxide Dismutase; Vagus Nerve | 2021 |
[Effects of astragalus (ASI, SK) on experimental liver injury].
Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Galactosamine; Glucosides; Glutathione; Male; Malondialdehyde; Mice; Microsomes, Liver; Rats; Saponins; Triterpenes | 1992 |
Anti-lipid peroxilative effect of ginsenoside Rb1 and Rg1.
Topics: Aging; Animals; Antioxidants; Female; Ginsenosides; Glutathione Peroxidase; Lipid Peroxidation; Malondialdehyde; Panax; Plants, Medicinal; Rats; Rats, Inbred Strains; Saponins; Superoxide Dismutase | 1991 |
[Protective effects of gypenosides on experimental myocardial infarction].
Topics: Animals; Drugs, Chinese Herbal; Fatty Acids, Nonesterified; Female; Male; Malondialdehyde; Myocardial Infarction; Myocardium; Plant Extracts; Rats; Rats, Inbred Strains; Saponins; Superoxide Dismutase | 1990 |
Anti-lipid peroxidation and protection of ginsenosides against cerebral ischemia-reperfusion injuries in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Creatine Kinase; Female; Ginsenosides; Ischemic Attack, Transient; Lipid Peroxidation; Male; Malondialdehyde; Panax; Plants, Medicinal; Rats; Rats, Inbred Strains; Reperfusion Injury; Saponins; Superoxide Dismutase; Thromboxane B2 | 1990 |
[Protective effects of Panax notoginseng saponins on experimental myocardial injury induced by ischemia and reperfusion in rat].
Topics: Animals; Calcium; Coronary Disease; Female; Ginsenosides; Male; Malondialdehyde; Myocardial Reperfusion Injury; Panax; Plants, Medicinal; Rats; Rats, Inbred Strains; Saponins; Superoxide Dismutase | 1990 |
Protective effects of ginsenosides on anoxia/reoxygenation of cultured rat myocytes and on reperfusion injuries against lipid peroxidation.
Topics: Animals; Cells, Cultured; Coronary Disease; Ginsenosides; Hypoxia; L-Lactate Dehydrogenase; Lipid Peroxides; Malondialdehyde; Myocardium; Rats; Saponins; Superoxide Dismutase | 1987 |
[Effects of total saponins of semen ziziphi Spinosae on brain damages and brain biochemical parameters under cerebral ischemia of rats].
Topics: Animals; Brain; Brain Ischemia; Drugs, Chinese Herbal; Female; L-Lactate Dehydrogenase; Lactates; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Saponins | 1996 |
Enhancement of membrane damage by saponins isolated from Acacia auriculiformis.
Topics: Acacia; Animals; Carbohydrate Sequence; Filaricides; Intracellular Membranes; Lipid Peroxidation; Malondialdehyde; Microsomes, Liver; Molecular Sequence Data; Parasites; Plant Extracts; Rats; Saponins; Triterpenes | 1997 |
A study of ginsenoside-Rd in a renal ischemia-reperfusion model.
Topics: Animals; Blood Urea Nitrogen; Catalase; Cell Line; Creatinine; Culture Media; Disease Models, Animal; Ginsenosides; Glutathione Peroxidase; Kidney; Kidney Tubules; L-Lactate Dehydrogenase; Male; Malondialdehyde; Rats; Rats, Wistar; Reperfusion Injury; Saponins; Superoxide Dismutase | 1998 |
Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration.
Topics: Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Fetus; Ginsenosides; Glutamic Acid; Lipid Peroxidation; Malondialdehyde; Nerve Degeneration; Neurons; Neurotoxins; Panax; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 1998 |
[Protective effect of active components extracted from radix Astragali on human erythrocyte membrane damages caused by reactive oxygen species].
Topics: Drugs, Chinese Herbal; Erythrocyte Membrane; Fabaceae; Flavonoids; Free Radical Scavengers; Humans; Lipid Peroxidation; Malondialdehyde; Plants, Medicinal; Polysaccharides; Saponins | 1996 |
Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Animals; Body Water; Burns; Central Nervous System Agents; Dinoprostone; Dogs; Female; Fluid Therapy; Ginsenosides; Hemodynamics; Humans; Hypnotics and Sedatives; Interleukin-1; Male; Malondialdehyde; Mitochondria; Multiple Organ Failure; Oxygen Consumption; Panax; Plants, Medicinal; Platelet Aggregation; Random Allocation; Reperfusion Injury; Saponins; Sepsis; Shock; Succinate Dehydrogenase; Superoxide Dismutase; Syndrome; Systemic Inflammatory Response Syndrome; Thromboxane B2; Tumor Necrosis Factor-alpha | 1998 |
Effect of ginsenoside-Rd in cephaloridine-induced renal disorder.
Topics: Animals; Blood Urea Nitrogen; Catalase; Cephaloridine; Cephalosporins; Creatinine; Ginsenosides; Glycosuria; Hypolipidemic Agents; Kidney Diseases; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipid Peroxidation; LLC-PK1 Cells; Male; Malondialdehyde; Potassium; Rats; Rats, Wistar; Reactive Oxygen Species; Saponins; Sodium; Superoxide Dismutase; Swine | 1999 |
Effect of aerobic exercise and ginsenosides on lipid metabolism in diet-induced hyperlipidemia mice.
Topics: Animals; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Ginsenosides; Hyperlipidemias; Lipid Metabolism; Liver; Male; Malondialdehyde; Mice; Panax; Physical Conditioning, Animal; Plants, Medicinal; Saponins; Superoxide Dismutase; Triglycerides | 1999 |
The role of ginsenoside-Rd in cisplatin-induced acute renal failure.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Antineoplastic Agents; Blood Urea Nitrogen; Catalase; Cells, Cultured; Cisplatin; Creatinine; Ginsenosides; Glutathione Peroxidase; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Male; Malondialdehyde; Panax; Phytotherapy; Plants, Medicinal; Rats; Rats, Wistar; Saponins; Superoxide Dismutase | 2000 |
Isoflavone aglycone-rich extract without soy protein attenuates atherosclerosis development in cholesterol-fed rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Chromans; Copper; Disease Models, Animal; Energy Intake; Equol; Fermentation; Genistein; Glycine max; Isoflavones; Lipids; Lipoproteins, LDL; Male; Malondialdehyde; Phenols; Rabbits; Saponins; Soybean Proteins | 2000 |
[Antilipid peroxidation and antiradiative action of glycosides in herba Cistanches].
Topics: Animals; DNA; Drugs, Chinese Herbal; Erythrocytes; Female; Lipid Peroxidation; Liver; Magnoliopsida; Male; Malondialdehyde; Mice; Radiation Injuries, Experimental; Random Allocation; RNA; Saponins; Spleen; Superoxide Dismutase; Whole-Body Irradiation | 1997 |
Protective effects of Panax ginseng on muscle injury and inflammation after eccentric exercise.
Topics: Animals; Biomarkers; Creatine Kinase; Glucosephosphate Dehydrogenase; Glucuronidase; Inflammation; Intubation, Gastrointestinal; Lipid Peroxidation; Male; Malondialdehyde; Muscle, Skeletal; Panax; Physical Conditioning, Animal; Plant Extracts; Rats; Rats, Wistar; Reference Values; Saponins; Time Factors | 2001 |
Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana.
Topics: Animals; Antimutagenic Agents; Antioxidants; Carbohydrate Sequence; Flowers; In Vitro Techniques; Isoflavones; Lipid Peroxidation; Liver; Male; Malondialdehyde; Molecular Sequence Data; Mutagens; Oleanolic Acid; Pueraria; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Saponins; Subcellular Fractions | 2002 |
The effects of the total saponin of Dipsacus asperoides on the damage of cultured neurons induced by beta-amyloid protein 25-35.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Hydro-Lyases; Lipid Peroxidation; Malondialdehyde; Neurons; Neuroprotective Agents; Oleanolic Acid; Oxidative Stress; Peptide Fragments; Rats; Saponins; Tetrazolium Salts; Thiazoles | 2002 |
[Effects of components isolated from Astragalus membranaceus Bunge on cardiac function injured by myocardial ischemia reperfusion in rats].
Topics: Animals; Astragalus propinquus; Cardiotonic Agents; Drugs, Chinese Herbal; Flavonoids; Heart Function Tests; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Plants, Medicinal; Random Allocation; Rats; Rats, Wistar; Saponins; Sodium-Potassium-Exchanging ATPase; Triterpenes | 2000 |
Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia.
Topics: Animals; Brain Chemistry; Brain Ischemia; Cardiotonic Agents; Catalase; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Reperfusion Injury; Saponins; Superoxide Dismutase; Triterpenes | 2004 |
Effect of iron on lipid peroxidation, and enzymatic and non-enzymatic antioxidants and bacoside-A content in medicinal plant Bacopa monnieri L.
Topics: Antioxidants; Bacopa; Iron; Lipid Peroxidation; Malondialdehyde; Peroxidases; Plant Leaves; Plant Roots; Plants, Medicinal; Saponins; Superoxide Dismutase; Triterpenes | 2006 |
[The protective effects of three components isolated from Astragalus membranaceus on shock wave lithotripsy induced kidney injury in rabbit model].
Topics: Animals; Astragalus propinquus; Drugs, Chinese Herbal; Endothelin-1; Flavonoids; High-Energy Shock Waves; Kidney Diseases; Lithotripsy; Male; Malondialdehyde; Polysaccharides; Protective Agents; Rabbits; Random Allocation; Saponins | 2005 |
[Effects of components isolated from Astragalus mongholicus on expression of p-selectin in shock wave induced kidney injury in rabbit model].
Topics: Animals; Astragalus propinquus; Flavonoids; Free Radical Scavengers; Kidney; Kidney Glomerulus; Kidney Tubules; Lithotripsy; Male; Malondialdehyde; P-Selectin; Plants, Medicinal; Polysaccharides; Rabbits; Random Allocation; Saponins; Superoxide Dismutase | 2005 |
[Effect of magnesium isoglycyrrhizinate on the proliferation and oxidative stress of rat hepatic stellate cells in vitro].
Topics: Animals; Cell Proliferation; Cells, Cultured; Hepatocytes; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase; Triterpenes | 2006 |
Copper-induced changes in the growth, oxidative metabolism, and saponin production in suspension culture roots of Panax ginseng in bioreactors.
Topics: Bioreactors; Cell Culture Techniques; Copper; Dehydroascorbic Acid; Glutathione Disulfide; Isoenzymes; Malondialdehyde; Oxidation-Reduction; Oxygen; Panax; Plant Proteins; Plant Roots; Saponins; Superoxides | 2006 |
[Protective effects of Denghuang injection on cerebral infarction in animal].
Topics: Alkaline Phosphatase; Animals; Astragalus propinquus; Behavior, Animal; Brain; Cerebral Infarction; Creatine Kinase; Dogs; Drug Combinations; Drugs, Chinese Herbal; Erigeron; Female; Flavonoids; Gerbillinae; L-Lactate Dehydrogenase; Male; Malondialdehyde; Neuroprotective Agents; Plants, Medicinal; Rats; Rats, Wistar; Saponins | 2006 |
Preliminary studies on antihepatotoxic effect of Physalis peruviana Linn. (Solanaceae) against carbon tetrachloride induced acute liver injury in rats.
Topics: Animals; Antioxidants; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Flavonoids; Glutathione; Hexanes; India; Lethal Dose 50; Liver; Liver Diseases; Male; Malondialdehyde; Phenols; Physalis; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Saponins; Solvents; Water | 2007 |
[Protective effects of Xinnao Shutong capsule on acute cerebral ischemic injury of multiple infarcts in rats].
Topics: Animals; Brain Infarction; Brain Ischemia; Capsules; Drugs, Chinese Herbal; Hippocampus; L-Lactate Dehydrogenase; Male; Malondialdehyde; Neuroprotective Agents; Plants, Medicinal; Random Allocation; Rats; Rats, Wistar; Saponins; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Tribulus | 2006 |
Modification of alterations in cardiac function and sarcoplasmic reticulum by astragaloside IV in myocardial injury in vivo.
Topics: Animals; Blood Pressure; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Creatine Kinase; Drugs, Chinese Herbal; Heart; Heart Injuries; Heart Rate; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardium; Phosphorylation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Saponins; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxide Dismutase; Triterpenes | 2007 |
Sasanquasaponin protects rat cardiomyocytes against oxidative stress induced by anoxia-reoxygenation injury.
Topics: Animals; Antioxidants; Calcium; Catalase; Cell Survival; Colorimetry; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glutathione Disulfide; Glutathione Peroxidase; Hypoxia; L-Lactate Dehydrogenase; Malondialdehyde; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Oxygen; Rats; Reactive Oxygen Species; Saponins; Superoxide Dismutase | 2007 |
Protective effects of sasanquasaponin on injury of endothelial cells induced by anoxia and reoxygenation in vitro.
Topics: Cell Adhesion; Cell Survival; Cells, Cultured; Endothelial Cells; Glutathione Peroxidase; Humans; Hypoxia; Intercellular Adhesion Molecule-1; L-Lactate Dehydrogenase; Lipid Peroxidation; Malondialdehyde; Mitochondrial Proteins; Neutrophils; NF-kappa B; Oxygen; Protective Agents; Saponins; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2007 |
Reinioside C, a triterpene saponin of Polygala aureocauda Dunn, exerts hypolipidemic effect on hyperlipidemic mice.
Topics: Animals; Calcium; Cell Proliferation; Cells, Cultured; Cholesterol; Cholesterol, LDL; Endothelial Cells; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins, LDL; Liver; Macrophages, Peritoneal; Male; Malondialdehyde; Mice; Molecular Structure; Myocytes, Smooth Muscle; Polygala; Saponins; Superoxide Dismutase; Triglycerides; Triterpenes | 2008 |
[Effects of CASI on myocardial ischemia-reperfusion arrhythmia in rats].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Drug Combinations; Drugs, Chinese Herbal; Electrocardiography; Eleutherococcus; Female; Ginsenosides; Glutathione Peroxidase; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Panax; Phytotherapy; Plants, Medicinal; Rats; Rats, Wistar; Saponins; Superoxide Dismutase | 2007 |
[Effects of AST and ASI on metabolism of free radical in senescent rats treated by HC].
Topics: Aging; Animals; Astragalus propinquus; Catalase; Cell Proliferation; Cerebral Cortex; Female; Free Radicals; Glutathione; Glutathione Disulfide; Hydrocortisone; Interleukin-2; Liver; Male; Malondialdehyde; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Saponins; Spleen; Superoxide Dismutase; Triterpenes | 2007 |
[Experimental study of saikosaponin-D (SSd) on lipid peroxidation of hepatic fibrosis on rat].
Topics: Animals; Aspartate Aminotransferases; Collagen Type IV; Dimethylnitrosamine; Hyaluronic Acid; Laminin; Lipid Peroxidation; Liver Cirrhosis; Malondialdehyde; Oleanolic Acid; Rats; Saponins; Superoxide Dismutase | 2008 |
SK-PC-B70M confers anti-oxidant activity and reduces Abeta levels in the brain of Tg2576 mice.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Antioxidants; Blotting, Western; Cell Death; Cells, Cultured; Cerebral Cortex; Cytoprotection; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hydrogen Peroxide; Male; Malondialdehyde; Mice; Mice, Transgenic; Neurons; Peptide Fragments; Plaque, Amyloid; Reactive Oxygen Species; Saponins | 2009 |
Inhibitory effects of Geijigajakyak-Tang on trinitrobenzene sulfonic acid-induced colitis.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antioxidants; Benzoates; Bridged-Ring Compounds; Chemotaxis; Colitis; Cyclohexanols; Eucalyptol; Female; Glucosides; Glycyrrhizic Acid; Ileum; Lipid Peroxidation; Magnoliopsida; Malondialdehyde; Mice; Mice, Inbred BALB C; Models, Animal; Monoterpenes; Muscle Contraction; Muscle, Smooth; Neutrophils; Parasympatholytics; Peroxidase; Phytotherapy; Plant Extracts; Saponins; Trinitrobenzenesulfonic Acid; Triterpenes | 2009 |
Antioxidant and apoptotic effects of korean white ginseng extracted with the same ratio of protopanaxadiol and protopanaxatriol saponins in human hepatoma HepG2 cells.
Topics: Antioxidants; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Caspase 3; Catalase; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Korea; Liver Neoplasms; Malondialdehyde; Mitogen-Activated Protein Kinases; Oxidants; Panax; Plant Extracts; Sapogenins; Saponins | 2009 |
A study on the antioxidant activity and tissues selective inhibition of lipid peroxidation by saponins from the roots of Platycodon grandiflorum.
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Free Radical Scavengers; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Myocardium; Plant Extracts; Plant Roots; Platycodon; Rats; Rats, Wistar; Saponins; Spleen; Thiobarbituric Acid Reactive Substances | 2009 |
Effect of purified saponin mixture from Astragalus corniculatus on enzyme- and non-enzyme-induced lipid peroxidation in liver microsomes from spontaneously hypertensive rats and normotensive rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Astragalus Plant; Carbon Tetrachloride; Disease Models, Animal; Iron Compounds; Lipid Peroxidation; Malondialdehyde; Microsomes, Liver; NADP; Oxidative Stress; Plant Extracts; Rats; Rats, Inbred SHR; Rats, Wistar; Saponins; Spectrophotometry | 2010 |
[Protective effect and mechanism of IPQDS on acute myocardial infarction in rats].
Topics: Animals; Aspartate Aminotransferases; Creatine Kinase; Drugs, Chinese Herbal; Female; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Infarction; Nitric Oxide; Rats; Rats, Wistar; Saponins; Superoxide Dismutase | 2009 |
The effects of ginseng total saponin, panaxadiol and panaxatriol on ischemia/reperfusion injury in isolated rat heart.
Topics: Adenosine Triphosphate; Animals; Creatine Kinase; Ginsenosides; Glutathione; Heart; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Panax; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins | 2010 |
Preliminary phytochemical screening and in vitro antioxidant activities of the aqueous extract of Helichrysum longifolium DC.
Topics: Antioxidants; Butylated Hydroxytoluene; Flavonoids; Gallic Acid; Helichrysum; Lipid Peroxidation; Malondialdehyde; Phenols; Phytosterols; Plant Extracts; Plant Leaves; Polyphenols; Proanthocyanidins; Reference Values; Saponins; Tannins | 2010 |
Protective effect of astragaloside on focal cerebral ischemia/reperfusion injury in rats.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Lactates; Male; Malondialdehyde; Nerve Growth Factor; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptor, trkA; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Saponins; Superoxide Dismutase; Time Factors; Triterpenes; Water | 2010 |
[Effects of Panax notoginseng saponins on ACE2 and TNF-alpha in rats with post-myocardial infarction-ventricular remodeling].
Topics: Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Disease Models, Animal; Female; Fosinopril; Glutathione Peroxidase; Male; Malondialdehyde; Myocardial Infarction; Myocardium; Nitric Oxide; Panax notoginseng; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Sprague-Dawley; Saponins; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2010 |
The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Caspase 3; Drugs, Chinese Herbal; Galactosamine; Glutathione; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Ornithogalum; Oxidative Stress; Phytotherapy; Protective Agents; Saponins; Survival Rate; Tumor Necrosis Factor-alpha | 2010 |
[Study on hepatotoxicity on rats caused by crude extracts of total saikosaponins and correlation with oxidative damage mechanism].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Humans; Liver; Male; Malondialdehyde; Oleanolic Acid; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Saponins; Superoxide Dismutase | 2010 |
SK-PC-B70M alleviates neurologic symptoms in G93A-SOD1 amyotrophic lateral sclerosis mice.
Topics: Aldehydes; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Cell Survival; Choline O-Acetyltransferase; Disease Models, Animal; Lipid Peroxidation; Malondialdehyde; Mice; Mice, Transgenic; Motor Activity; Saponins; Spinal Cord; Superoxide Dismutase | 2011 |
[Observation of anti-oxidation effect of total Panax japonicus saponins on cerebral ischemia/reperfusion injury in rats].
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Male; Malondialdehyde; Panax; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Superoxide Dismutase | 2008 |
[Effect of inhibiting endoxin by antidigoxin antiserum on myocardial ischemia/reperfusion injury in rats].
Topics: Animals; Cardenolides; Digoxin; Immune Sera; Malondialdehyde; Myocardial Reperfusion; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Saponins; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2007 |
The antioxidant effects of garlic saponins protect PC12 cells from hypoxia-induced damage.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Catalase; Cell Differentiation; Cell Hypoxia; Cell Nucleus; Cell Survival; Deoxyguanosine; Garlic; Gene Expression Regulation; Malondialdehyde; Neurites; Neurons; Oxidative Stress; PC12 Cells; Plant Roots; Protein Transport; Rats; RNA, Messenger; Saponins; Transcription Factor RelA; Tubulin | 2011 |
[Protective effect of astragalosides on anoxia/reoxygenation injury of hippocampal neuron].
Topics: Animals; Calcium; Cell Hypoxia; Female; Fetus; Hippocampus; Malondialdehyde; Neurons; Neuroprotective Agents; Nitric Oxide; Pregnancy; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Superoxide Dismutase; Triterpenes | 2010 |
[Effect of gross saponins of Tribulus terrestris on cardiocytes impaired by adriamycin].
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Aspartate Aminotransferases; Caspase 3; Cell Survival; Cells, Cultured; Creatine Kinase; Doxorubicin; L-Lactate Dehydrogenase; Malondialdehyde; Myocytes, Cardiac; Nitric Oxide; Rats; Rats, Wistar; Saponins; Superoxide Dismutase; Tribulus | 2010 |
Injectable caltrop fruit saponin protects against ischemia-reperfusion injury in rat brain.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Calcium Channel Blockers; Cerebral Infarction; Cerebrum; Endothelins; Forelimb; Fruit; Infarction, Middle Cerebral Artery; Injections; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Reperfusion Injury; Saponins; Superoxide Dismutase; Thromboxane B2; Tribulus | 2011 |
Astragaloside IV improves metabolic syndrome and endothelium dysfunction in fructose-fed rats.
Topics: Animals; Blood Pressure; Body Weight; Cyclic GMP; Endothelium, Vascular; Fructose; Glucose Tolerance Test; Male; Malondialdehyde; Metabolic Syndrome; Rats; Rats, Sprague-Dawley; Saponins; Triterpenes; Vasodilation | 2011 |
[Effect of astragaloside against the oxidative damage on endothelial cells].
Topics: Cells, Cultured; Endothelial Cells; Humans; Leukocytes, Mononuclear; Lipoproteins, LDL; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Saponins; Stem Cells; Triterpenes | 2011 |
Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress.
Topics: 1-Butanol; Animals; Antioxidants; Blood Coagulation; Diet, High-Fat; Dioscorea; Disease Models, Animal; Drugs, Chinese Herbal; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Lipids; Lovastatin; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Rats; Rats, Sprague-Dawley; Rhizome; Saponins; Solvents; Superoxide Dismutase | 2012 |
Hepatoprotective effects of total saponins isolated from Taraphochlamys affinis against carbon tetrachloride induced liver injury in rats.
Topics: Animals; Apocynaceae; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins | 2012 |
Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia.
Topics: Animals; Astragalus Plant; Cardiovascular Agents; Caspase 3; Disease Models, Animal; Drug Synergism; Glucose; Hippocampus; Ischemic Attack, Transient; Male; Malondialdehyde; Neuroprotective Agents; Nimodipine; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Positron-Emission Tomography; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Saponins; Superoxide Dismutase; Triterpenes | 2012 |
Cardioprotective effects of saponins from Panax japonicus on acute myocardial ischemia against oxidative stress-triggered damage and cardiac cell death in rats.
Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Caspase 3; Cell Death; Creatine Kinase; Heart; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Panax; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Saponins; Superoxide Dismutase; Xanthines | 2012 |
Saponin rich fractions from Polygonatum odoratum (Mill.) Druce with more potential hypoglycemic effects.
Topics: 1-Butanol; Alkanes; Animals; Blood Glucose; Chemical Fractionation; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Ethanol; Flavonoids; Glycoside Hydrolases; Hep G2 Cells; Humans; Hypoglycemic Agents; Liver; Male; Malondialdehyde; Phytotherapy; Plants, Medicinal; Polygonatum; Rats; Rats, Sprague-Dawley; Rhizome; Saponins; Solvents; Superoxide Dismutase; Time Factors; Water | 2012 |
[Effects of two different extracts of total saponins from Cicer arietinum on kidney of T2DM rats].
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Glucose; Blood Urea Nitrogen; Cicer; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelin-1; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Kidney; Male; Malondialdehyde; Plants, Medicinal; Random Allocation; Rats; Rats, Wistar; Saponins; Superoxide Dismutase; Thromboxane B2 | 2012 |
Protective effects of a purified saponin mixture from Astragalus corniculatus Bieb., in vivo hepatotoxicity models.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Astragalus Plant; Biotransformation; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutathione; L-Lactate Dehydrogenase; Liver; Liver Function Tests; Male; Malondialdehyde; Plant Extracts; Rats; Rats, Wistar; Saponins; Silymarin | 2013 |
Madecassoside, a triterpenoid saponin isolated from Centella asiatica herbs, protects endothelial cells against oxidative stress.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Nucleus Shape; Cell Shape; Cell Survival; Cells, Cultured; Centella; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glutathione; Human Umbilical Vein Endothelial Cells; Humans; L-Lactate Dehydrogenase; Malondialdehyde; Membrane Potential, Mitochondrial; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Protein Processing, Post-Translational; Saponins; Triterpenes | 2012 |
Anti-atherosclerotic activity of platycodin D derived from roots of Platycodon grandiflorum in human endothelial cells.
Topics: Atherosclerosis; Cell Adhesion; Cell Adhesion Molecules; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Malondialdehyde; Monocytes; Nitric Oxide; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Roots; Platycodon; RNA, Messenger; Saponins; Triterpenes; Vascular Cell Adhesion Molecule-1 | 2012 |
[Effect of magnesium isoglycyrrhizinate on PLA2 during liver tissue injury following limb ischemia/reperfusion in rats].
Topics: Animals; Extremities; Liver; Male; Malondialdehyde; Phospholipases A2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Triterpenes | 2012 |
Timosaponin-BII inhibits the up-regulation of BACE1 induced by ferric chloride in rat retina.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Anemarrhena; Animals; Antioxidants; Chlorides; Disease Models, Animal; Drugs, Chinese Herbal; Ferric Compounds; Male; Malondialdehyde; Oxidative Stress; Partial Thromboplastin Time; Phytotherapy; Rats; Rats, Sprague-Dawley; Retina; Rhizome; Saponins; Steroids; Up-Regulation | 2012 |
Neuroprotective effects of bacopaside I in ischemic brain injury.
Topics: Animals; Behavior, Animal; Brain; Brain Ischemia; Catalase; Energy Metabolism; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase; Triterpenes | 2013 |
[Effects of total saponin from Panax japonicus on acute myocardial ischemia injury induced by ligating coronary artery left anterior descending branch in rats].
Topics: Acute Disease; Animals; Antioxidants; Cardiotonic Agents; Catalase; Disease Models, Animal; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardium; Oxidative Stress; Panax; Random Allocation; Rats; Rats, Wistar; Saponins; Superoxide Dismutase | 2012 |
[Effects of ginseng total saponin on traumatic brain edema of rats].
Topics: Animals; Brain Edema; Brain Injuries; Interleukin-1beta; Male; Malondialdehyde; Panax; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2012 |
The antidepressant-like effect of bacopaside I: possible involvement of the oxidative stress system and the noradrenergic system.
Topics: Administration, Oral; Animals; Antidepressive Agents; Blepharoptosis; Catalase; Dose-Response Relationship, Drug; Glutathione Peroxidase; Hypothermia; Locomotion; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Monoamine Oxidase; Norepinephrine; Oxidative Stress; Reserpine; Saponins; Serotonin; Stress, Physiological; Superoxide Dismutase; Swimming; Triterpenes | 2013 |
Clematichinenoside attenuates myocardial infarction in ischemia/reperfusion injury both in vivo and in vitro.
Topics: Animals; Antioxidants; Clematis; Creatine Kinase; Drugs, Chinese Herbal; Guinea Pigs; Heart Ventricles; Hemodynamics; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 2013 |
Anti-fibrosis and anti-cirrhosis effects of Rhizoma paridis saponins on diethylnitrosamine induced rats.
Topics: Animals; Diethylnitrosamine; DNA Fragmentation; Gene Expression Regulation; Liver Cirrhosis; Liver Cirrhosis, Experimental; Magnetic Resonance Spectroscopy; Male; Malondialdehyde; Plants; Rats; Rats, Wistar; Rhizome; Saponins; Superoxide Dismutase | 2014 |
Panax notoginseng saponins improve erectile function through attenuation of oxidative stress, restoration of Akt activity and protection of endothelial and smooth muscle cells in diabetic rats with erectile dysfunction.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelial Cells; Erectile Dysfunction; Glutathione; Humans; Immunohistochemistry; Male; Malondialdehyde; Microscopy, Electron; Myocytes, Smooth Muscle; Oxidative Stress; Panax notoginseng; Penis; Plant Extracts; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 2014 |
Saponins from Aralia taibaiensis attenuate D-galactose-induced aging in rats by activating FOXO3a and Nrf2 pathways.
Topics: Aging; Animals; Antioxidants; Aralia; Forkhead Box Protein O3; Forkhead Transcription Factors; Galactose; Liver; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins; Signal Transduction; Spleen; Thymus Gland | 2014 |
Protective mechanism of Panax notoginseng saponins on rat hemorrhagic shock model in recovery stage.
Topics: Animals; Disease Models, Animal; Endotoxins; Enzyme-Linked Immunosorbent Assay; Intercellular Adhesion Molecule-1; Interleukin-6; Lung; Male; Malondialdehyde; Panax notoginseng; Peroxidase; Protective Agents; Rats; Rats, Wistar; Saponins; Shock, Hemorrhagic; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Hypoglycemic effect of Gynostemma pentaphyllum saponins by enhancing the Nrf2 signaling pathway in STZ-inducing diabetic rats.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Gynostemma; Hypoglycemic Agents; Insulin; Kidney; Lipids; Liver; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Saponins; Signal Transduction; Superoxide Dismutase | 2016 |
NG as a novel nitric oxide donor induces apoptosis by increasing reactive oxygen species and inhibiting mitochondrial function in MGC803 cells.
Topics: Acetylcysteine; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Azo Compounds; bcl-2-Associated X Protein; Caspase 9; Cell Proliferation; Glutathione; Glutathione Peroxidase; Humans; Malondialdehyde; Membrane Potential, Mitochondrial; Methionine Sulfoximine; Mitochondria; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Prodrugs; Proto-Oncogene Proteins c-bcl-2; Saponins; Stomach Neoplasms; Superoxide Dismutase | 2014 |
Saikosaponin-D attenuates heat stress-induced oxidative damage in LLC-PK1 cells by increasing the expression of anti-oxidant enzymes and HSP72.
Topics: Animals; Bupleurum; Catalase; Dose-Response Relationship, Drug; Glutathione Peroxidase; Heat-Shock Response; Hot Temperature; HSP72 Heat-Shock Proteins; LLC-PK1 Cells; Malondialdehyde; Oleanolic Acid; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Saponins; Superoxide Dismutase; Swine | 2014 |
Soyasaponins can blunt inflammation by inhibiting the reactive oxygen species-mediated activation of PI3K/Akt/NF-kB pathway.
Topics: Animals; Cell Line; Chromones; Cyclooxygenase 2; Dinoprostone; Glycine max; I-kappa B Kinase; Inflammation; Lipopolysaccharides; Macrophages; Malondialdehyde; Mice; Morpholines; Nitriles; Oleanolic Acid; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Saponins; Signal Transduction; Sulfones; Superoxide Dismutase; Transcription Factor RelA | 2014 |
Soyasaponins prevent H₂O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells.
Topics: Animals; Catalase; Cell Communication; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Free Radical Scavengers; Gap Junctions; Glutathione Peroxidase; Glycine max; Hepatocytes; Hydrogen Peroxide; Lipid Peroxidation; Liver; Malondialdehyde; Rats; Reactive Oxygen Species; Saponins; Superoxide Dismutase | 2014 |
Effect of saponin on the phytoextraction of Pb, Cd and Zn from soil using Italian ryegrass.
Topics: Antioxidants; Biodegradation, Environmental; Cadmium; China; Environmental Monitoring; Environmental Pollution; Free Radicals; Italy; Lead; Lolium; Malondialdehyde; Metals, Heavy; Oxygen; Plant Roots; Plant Shoots; Reference Values; Saponins; Soil; Soil Pollutants; Surface-Active Agents; Zinc | 2015 |
[Comparative study of main components of ginseng on immune function of rats].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Brain; Corticosterone; Ginsenosides; Glutathione; Immune System; Interferon-gamma; Interleukin-2; Interleukin-6; Killer Cells, Natural; Malondialdehyde; Nitric Oxide; Organ Size; Panax; Polysaccharides; Random Allocation; Rats, Wistar; Saponins; Spleen; Superoxide Dismutase; Thymus Gland; Thyrotropin | 2014 |
Protective effect of panax notoginseng saponins on acute ethanol-induced liver injury is associated with ameliorating hepatic lipid accumulation and reducing ethanol-mediated oxidative stress.
Topics: Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Ethanol; Glutathione; Humans; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Panax notoginseng; Reactive Oxygen Species; Saponins; Triglycerides | 2015 |
[Study on protective effect of Panax notoginseng total saponins on H9c2 cells senescence against D-galactose].
Topics: Apoptosis; Cell Line; Cellular Senescence; Fluoresceins; Galactose; Malondialdehyde; Panax notoginseng; Protective Agents; Saponins | 2014 |
The protective effect of astragaloside IV against benzo[a]pyrene induced endothelial progenitor cell dysfunction.
Topics: Analysis of Variance; Benzo(a)pyrene; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Progenitor Cells; Enzyme-Linked Immunosorbent Assay; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Interleukin-1beta; Malondialdehyde; Nicotiana; Receptor for Advanced Glycation End Products; Saponins; Triterpenes; Tumor Necrosis Factor-alpha | 2015 |
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Collagen; Down-Regulation; Fibronectins; Fruit; Glutathione; Hydroxyproline; Liver; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rosa; Saponins; Signal Transduction; Superoxide Dismutase | 2015 |
UPLC/Q-TOFMS-Based Metabolomics Studies on the Protective Effect of Panax notoginseng Saponins on Alcoholic Liver Injury.
Topics: Animals; Chromatography, Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Glutathione; Hepatitis, Alcoholic; Liver; Male; Malondialdehyde; Mass Spectrometry; Metabolomics; Mice, Inbred C57BL; Panax notoginseng; Phytotherapy; Reactive Oxygen Species; Saponins; Superoxide Dismutase | 2015 |
Preventive effects of Ecliptae Herba extract and its component, ecliptasaponin A, on bleomycin-induced pulmonary fibrosis in mice.
Topics: Actins; Animals; Bleomycin; Cyclooxygenase 2; Eclipta; Hydroxyproline; Lung; Male; Malondialdehyde; Matrix Metalloproteinases; Mice, Inbred ICR; Plant Components, Aerial; Plant Extracts; Pulmonary Fibrosis; Saponins; Superoxide Dismutase; Transforming Growth Factor beta1 | 2015 |
Curcumin alleviated the toxic reaction of Rhizoma Paridis saponins in a 45-day subchronic toxicological assessment of rats.
Topics: Alanine Transaminase; Animals; Curcumin; Cyclooxygenase 2; Glutathione Transferase; Heme Oxygenase-1; Interleukin-1beta; Liliales; Liver; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Rhizome; Saponins; Toxicity Tests, Subchronic; Up-Regulation | 2016 |
Protective Effect of Astragaloside IV Against Paraquat-Induced Lung Injury in Mice by Suppressing Rho Signaling.
Topics: Acute Lung Injury; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Catalase; Drugs, Chinese Herbal; Enzyme Activation; Glutathione Peroxidase; Interleukin-6; Lung; Malondialdehyde; Mice; Mice, Inbred BALB C; NF-kappa B; Oxidative Stress; Paraquat; Peroxidase; Random Allocation; rho GTP-Binding Proteins; rho-Associated Kinases; Saponins; Signal Transduction; Superoxide Dismutase; Thioredoxins; Triterpenes; Tumor Necrosis Factor-alpha | 2016 |
Cardioprotective effect of total saponins from three medicinal species of Dioscorea against isoprenaline-induced myocardial ischemia.
Topics: Animals; Aspartate Aminotransferases; Cardiotonic Agents; Catalase; Creatine Kinase; Dioscorea; Glutathione Peroxidase; Isoproterenol; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Ischemia; Myocardium; Phytotherapy; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 2015 |
Panax notoginseng saponins protect kidney from diabetes by up-regulating silent information regulator 1 and activating antioxidant proteins in rats.
Topics: Acetylation; Animals; Antioxidants; Blood Glucose; Bone Morphogenetic Protein 7; Chemokine CCL2; Diabetes Mellitus, Experimental; Gene Knockdown Techniques; Immunohistochemistry; Kidney; Kidney Function Tests; Lipids; Male; Malondialdehyde; Mesangial Cells; Oxidative Stress; Panax notoginseng; Plasminogen Activator Inhibitor 1; Protective Agents; Rats, Sprague-Dawley; Saponins; Sirtuin 1; Superoxide Dismutase; Transcription Factor RelA; Transcription, Genetic; Transforming Growth Factor beta1; Up-Regulation | 2016 |
[Protective Effect of Total Saponins of Panax japonicus Against H2O2-Induced Oxidative Stress Damage].
Topics: Antioxidants; Cell Line, Tumor; Cell Survival; China; Humans; Hydrogen Peroxide; Malondialdehyde; Oxidative Stress; Panax; Saponins; Superoxide Dismutase; Up-Regulation | 2015 |
Gastroprotective Effects of Astragaloside IV against Acute Gastric Lesion in Rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Chemokine CCL2; Gastric Mucosa; HSP70 Heat-Shock Proteins; Male; Malondialdehyde; Omeprazole; Phospholipase C gamma; Rats; Rats, Sprague-Dawley; Saponins; Stomach Ulcer; Superoxide Dismutase; Triterpenes; Tumor Necrosis Factor-alpha | 2016 |
Neuroprotective effects of polygalacic acid on scopolamine-induced memory deficits in mice.
Topics: Acetylcholinesterase; Animals; Choline O-Acetyltransferase; Glutathione; Hippocampus; Interleukins; Male; Malondialdehyde; Maze Learning; Memory; Memory Disorders; Mice; Neuroprotective Agents; Oleanolic Acid; Oxidative Stress; Polygala; Random Allocation; Saponins; Scopolamine; Superoxide Dismutase | 2016 |
Trillin Reduces Liver Chronic Inflammation and Fibrosis in Carbon Tetrachloride (CCl4) Induced Liver Injury in Mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Carbon Tetrachloride; Dioscorea; Enzyme-Linked Immunosorbent Assay; Hepatitis; Humans; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Liver Cirrhosis; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-kappa B; Saponins; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2016 |
Platycodin D protects against cigarette smoke-induced lung inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cigarette Smoking; Heme Oxygenase-1; Humans; Interleukin-1beta; Lymphotoxin-alpha; Male; Malondialdehyde; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Pneumonia; Pulmonary Disease, Chronic Obstructive; Saponins; Triterpenes | 2017 |
Nephroprotective Effects of Saponins from Leaves of Panax quinquefolius against Cisplatin-Induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cisplatin; Cytokines; Glutathione; Inflammation; Kidney; Male; Malondialdehyde; Mice, Inbred ICR; Neuroprotective Agents; Oxidative Stress; Panax; Plant Leaves; Saponins; Superoxide Dismutase | 2017 |
Onjisaponin B prevents cognitive impairment in a rat model of D-galactose-induced aging.
Topics: Aging; Animals; Avoidance Learning; Cognition Disorders; Disease Models, Animal; Galactose; Glutathione Peroxidase; Hippocampus; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Maze Learning; NF-kappa B; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase; Triterpenes; Tumor Necrosis Factor-alpha | 2018 |
Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the HL‑7702 cell line.
Topics: Apoptosis; Carbon Tetrachloride; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cytokines; Inflammasomes; Inflammation Mediators; Liver; Malondialdehyde; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Oxidative Stress; Saponins | 2018 |
[Protective effects and underlying mechanisms of Panax notoginseng saponins against SH-SY5Y cell apoptosis induced by 6-hydroxydopamine].
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Glutathione Peroxidase; Humans; Malondialdehyde; Membrane Potential, Mitochondrial; Oxidative Stress; Oxidopamine; Panax notoginseng; Reactive Oxygen Species; Saponins; Superoxide Dismutase | 2016 |
NF-κB and AMPK/PI3K/Akt signaling pathways are involved in the protective effects of Platycodon grandiflorum saponins against acetaminophen-induced acute hepatotoxicity in mice.
Topics: Acetaminophen; Aldehydes; AMP-Activated Protein Kinases; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Glutathione; Interleukin-1beta; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Roots; Platycodon; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Effect of astragaloside IV on indoxyl sulfate-induced kidney injury in mice via attenuation of oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Deoxyguanosine; Indican; Interleukin-1beta; Interleukin-6; Kidney; Kidney Diseases; Male; Malondialdehyde; Mice, Inbred C57BL; Oxidative Stress; Saponins; Superoxide Dismutase; Triterpenes | 2018 |
Platycodin D protects acetaminophen-induced hepatotoxicity by inhibiting hepatocyte MAPK pathway and apoptosis in C57BL/6J mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Glutathione; Hepatocytes; Inflammation; Liver; Male; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Oxidative Stress; Platycodon; Protective Agents; Saponins; Triterpenes | 2018 |
Total Saponins of Aralia Elata (Miq) Seem Alleviate Calcium Homeostasis Imbalance and Endoplasmic Reticulum Stress-Related Apoptosis Induced by Myocardial Ischemia/Reperfusion Injury.
Topics: Animals; Apoptosis; Aralia; bcl-2-Associated X Protein; Calcium; Creatine Kinase; Down-Regulation; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Saponins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxide Dismutase; Transcription Factor CHOP | 2018 |
Responses of the weed Bidens pilosa L. to exogenous application of the steroidal saponin protodioscin and plant growth regulators 24-epibrassinolide, indol-3-acetic acid and abscisic acid.
Topics: Abscisic Acid; Antioxidants; Bidens; Brassinosteroids; Diosgenin; Dose-Response Relationship, Drug; Flowers; Germination; Indoleacetic Acids; Malondialdehyde; Plant Growth Regulators; Plant Proteins; Plant Roots; Saponins; Seedlings; Steroids, Heterocyclic | 2019 |
Astragaloside IV reversed the autophagy and oxidative stress induced by the intestinal microbiota of AIS in mice.
Topics: Animals; Antioxidants; Autophagy; Autophagy-Related Protein 12; Bacteria; Beclin-1; Brain; Disease Models, Animal; Fatty Acids; Feces; Gastrointestinal Microbiome; Genetic Vectors; Glutathione; Homocysteine; Ischemic Attack, Transient; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; NADPH Oxidase 2; NADPH Oxidase 4; Oxidative Stress; Reactive Oxygen Species; Saponins; Stroke; Superoxide Dismutase; Triterpenes | 2018 |
Magnesium isoglycyrrhizinate alleviates liver injury in obese rats with acute necrotizing pancreatitis.
Topics: Animals; Inflammation; Liver; Male; Malondialdehyde; Neutrophils; NF-kappa B; Obesity; Oxidative Stress; Pancreas; Pancreatitis, Acute Necrotizing; Protective Agents; Rats, Sprague-Dawley; Saponins; Triterpenes | 2019 |
Protective Effects of Astragaloside IV Combined with Budesonide in Bronchitis in Rats by Regulation of Nrf2/Keap1 Pathway.
Topics: Animals; Bronchitis; Budesonide; Drug Combinations; Female; Glutathione Peroxidase; Kelch-Like ECH-Associated Protein 1; Lung; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins; Signal Transduction; Superoxide Dismutase; Triterpenes | 2018 |
Astragaloside IV ameliorates endoplasmic reticulum stress‑induced apoptosis of Aβ25‑35‑treated PC12 cells by inhibiting the p38 MAPK signaling pathway.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Disease Models, Animal; Endoplasmic Reticulum Stress; Humans; Malondialdehyde; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Peptide Fragments; Rats; Reactive Oxygen Species; Saponins; Signal Transduction; Superoxide Dismutase; Triterpenes | 2019 |
Saikosaponin a ameliorates lipopolysaccharide and d‑galactosamine-induced liver injury via activating LXRα.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Galactosamine; Hep G2 Cells; Humans; Interleukin-1beta; Lipopolysaccharides; Liver; Liver X Receptors; Malondialdehyde; Mice, Inbred C57BL; Oleanolic Acid; Peroxidase; Saponins; Tumor Necrosis Factor-alpha | 2019 |
Protective effects of Panax notoginseng saponins on PME-Induced nephrotoxicity in mice.
Topics: Animals; Apoptosis; Caspases; Cell Line; Colistin; Drugs, Chinese Herbal; Enzyme Activation; Female; Glutathione; Glutathione Peroxidase; Kidney; Malondialdehyde; Mice, Inbred ICR; Mitochondria; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Saponins; Superoxide Dismutase | 2019 |
Ameliorative effect of Magnesium Isoglycyrrhizinate on hepatic encephalopathy by Epirubicin.
Topics: Animals; Antibiotics, Antineoplastic; Carrier Proteins; Cognitive Dysfunction; Cytokines; Epirubicin; Hepatic Encephalopathy; Hippocampus; Male; Malondialdehyde; Memory; Mice, Inbred BALB C; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Saponins; Spatial Learning; Superoxide Dismutase; Thioredoxins; Triterpenes | 2019 |
Saponins of Panax japonicus Confer Neuroprotection against Brain Aging through Mitochondrial Related Oxidative Stress and Autophagy in Rats.
Topics: Aging; Animals; Apoptosis; Autophagy; Brain; Male; Malondialdehyde; Mitochondria; Neuroprotective Agents; Oxidative Stress; Panax; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Saponins; Sirtuin 1; Superoxide Dismutase | 2020 |
Lipidomics Analysis of Timosaponin BII in INS-1 Cells Induced by Glycolipid Toxicity and Its Relationship with Inflammation.
Topics: Anemarrhena; Animals; Cell Survival; Discriminant Analysis; Glutathione; Glycolipids; Inflammation; Insulin-Secreting Cells; Interleukin-1beta; Lipidomics; Macrophages; Malondialdehyde; Mice; Nitric Oxide; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Principal Component Analysis; Protective Agents; RAW 264.7 Cells; Saponins; Steroids | 2020 |
Protective Effect of Saponins-Enriched Fraction of Gynostemma pentaphyllum against High Choline-Induced Vascular Endothelial Dysfunction and Hepatic Damage in Mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Choline; Endothelium, Vascular; Glutathione Peroxidase; Gynostemma; Liver; Malondialdehyde; Methylamines; Mice; Nitric Oxide Synthase Type III; Oxidative Stress; Plant Extracts; Saponins; Thromboxane A2; Triglycerides | 2020 |
Astragaloside IV protects human cardiomyocytes from hypoxia/reoxygenation injury by regulating miR-101a.
Topics: Apoptosis; Cell Hypoxia; Cell Proliferation; Cell Survival; Computational Biology; Gene Expression Profiling; Humans; Inflammation; L-Lactate Dehydrogenase; Malondialdehyde; MAP Kinase Signaling System; MicroRNAs; Myocardial Reperfusion Injury; Myocytes, Cardiac; Receptor, Transforming Growth Factor-beta Type I; Regeneration; Saponins; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 2; Triterpenes | 2020 |
Saponins derived from the stems and leaves of Panax ginseng attenuate scrotal heat-induced spermatogenic damage via inhibiting the MAPK mediated oxidative stress and apoptosis in mice.
Topics: Animals; Apoptosis; Glutathione; Heme Oxygenase-1; Hot Temperature; HSP70 Heat-Shock Proteins; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Malondialdehyde; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Inbred ICR; Oxidative Stress; Panax; Saponins; Spermatogenesis; Superoxide Dismutase; Testis; Testosterone | 2021 |
Astragaloside IV ameliorates preeclampsia-induced oxidative stress through the Nrf2/HO-1 pathway in a rat model.
Topics: Animals; Blood Pressure; Disease Models, Animal; Female; Glutathione; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Saponins; Signal Transduction; Triterpenes; Vascular Endothelial Growth Factor Receptor-1 | 2020 |
Triterpenoid Saponin AG8 from
Topics: Acetylcysteine; Apoptosis; Ardisia; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Female; Glutathione; Humans; Malondialdehyde; Mitochondria; Oncogene Protein v-akt; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Saponins; Signal Transduction; Superoxide Dismutase; Triple Negative Breast Neoplasms; Triterpenes | 2020 |
Protection by ginseng saponins against cyclophosphamide-induced liver injuries in rats by induction of cytochrome P450 expression and mediation of the l-arginine/nitric oxide pathway based on metabolomics.
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cytochrome P-450 Enzyme System; Glutathione; Male; Malondialdehyde; Metabolomics; Nitric Oxide; Oxidative Stress; Panax; Rats; Rats, Sprague-Dawley; Saponins; Signal Transduction; Tumor Necrosis Factor-alpha | 2021 |
Antioxidant, Anti-Aging and Organ Protective Effects of Total Saponins from
Topics: Aging; Animals; Antioxidants; Aralia; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Free Radical Scavengers; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Saponins | 2021 |
Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K.
Topics: Apoptosis; Cell Line, Tumor; Glutamic Acid; Heme Oxygenase-1; Humans; Malondialdehyde; Neurodegenerative Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Saponins; Signal Transduction | 2022 |
Anemoside B4 prevents chronic obstructive pulmonary disease through alleviating cigarette smoke-induced inflammatory response and airway epithelial hyperplasia.
Topics: Animals; Anti-Inflammatory Agents; Catalase; Cigarette Smoking; Glutathione Peroxidase; Humans; Hyperplasia; Inflammation; Interleukin-8; Malondialdehyde; Mice; Mice, Inbred C57BL; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Saponins; Superoxide Dismutase; Transcription Factor AP-1; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2022 |
[Components and lipid-lowering effect of total saponins from underground part of Gynostemma pentaphyllum].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Bilirubin; Cholesterol, LDL; Diet, High-Fat; Gynostemma; Hypolipidemic Agents; Lipoproteins, HDL; Liver; Malondialdehyde; Peroxisome Proliferator-Activated Receptors; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase; Triglycerides; Trisaccharides | 2022 |