Compounds > malabaricone b
Page last updated: 2024-09-04

malabaricone b and indomethacin

malabaricone b has been researched along with indomethacin in 3 studies

Compound Research Comparison

Studies
(malabaricone b)		Trials
(malabaricone b)		Recent Studies (post-2010)
(malabaricone b)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
150929,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomymalabaricone b (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bandyopadhyay, SK; Banerjee, D; Bauri, AK; Chattopadhyay, S; Guha, RK1
Bandivdeker, AH; Bandyopadhyay, SK; Banerjee, D; Chattopadhyay, S; Maity, B1
Bandyopadhyay, SK; Banerjee, D; Chattopadhyay, S; Maity, B1

Other Studies

3 other study(ies) available for malabaricone b and indomethacin

ArticleYear
Healing properties of malabaricone B and malabaricone C, against indomethacin-induced gastric ulceration and mechanism of action.
    European journal of pharmacology, 2008, Jan-14, Volume: 578, Issue:2-3

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Fruit; Gastric Mucins; Gastric Mucosa; Glycogen; Indomethacin; Lipid Peroxidation; Male; Membrane Proteins; Mice; Myristicaceae; Omeprazole; Oxidative Stress; Periodic Acid-Schiff Reaction; Plant Extracts; Protein Carbonylation; Resorcinols; Stomach; Stomach Ulcer; Time Factors; Wound Healing

2008
Angiogenic and cell proliferating action of the natural diarylnonanoids, malabaricone B and malabaricone C during healing of indomethacin-induced gastric ulceration.
    Pharmaceutical research, 2008, Volume: 25, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cell Proliferation; Dose-Response Relationship, Drug; Endostatins; Epidermal Growth Factor; Gastric Mucosa; Granulation Tissue; Indomethacin; Male; Mice; Misoprostol; Neovascularization, Physiologic; Omeprazole; Regional Blood Flow; Resorcinols; Stomach Ulcer; Vascular Endothelial Growth Factor A; von Willebrand Factor

2008
Regulation of arginase/nitric oxide synthesis axis via cytokine balance contributes to the healing action of malabaricone B against indomethacin-induced gastric ulceration in mice.
    International immunopharmacology, 2009, Volume: 9, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arginase; Cytokines; Indomethacin; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Omeprazole; Peroxidase; Resorcinols; Stomach Ulcer

2009