majonoside-r2 and peroxynitric-acid

majonoside-r2 has been researched along with peroxynitric-acid* in 1 studies

Other Studies

1 other study(ies) available for majonoside-r2 and peroxynitric-acid

Article	Year
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis. Cancer letters, 1999, Dec-01, Volume: 147, Issue:1-2 In the course of our continuing search for novel cancer chemopreventive agents from natural sources, several kinds of Panax plants were screened. Consequently, the ocotillol-type saponin, majonoside-R2 (MR2), was obtained from the rhizome and root of Panax vietnamensis (Vietnamese ginseng) as an active constituent. MR2 exhibited potent anti-tumor-promoting activity on two-stage carcinogenesis test of mouse hepatic tumor using N-nitrosodiethylamine (DEN) as an initiator and phenobarbital (PB) as a promoter. Further, MR2 exhibited the remarkable inhibitory effect on two-stage carcinogenesis test of mouse skin induced by nitric oxide (NO) donor/12-O-tetradecanoylphorbol-13-acetate (TPA) or peroxynitrite/TPA. Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Female; Focal Nodular Hyperplasia; Ginsenosides; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Mice, Inbred SENCAR; Nitrates; Nitro Compounds; Panax; Papilloma; Phenobarbital; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vietnam	1999

Article

Year

Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.

Cancer letters, 1999, Dec-01, Volume: 147, Issue:1-2

In the course of our continuing search for novel cancer chemopreventive agents from natural sources, several kinds of Panax plants were screened. Consequently, the ocotillol-type saponin, majonoside-R2 (MR2), was obtained from the rhizome and root of Panax vietnamensis (Vietnamese ginseng) as an active constituent. MR2 exhibited potent anti-tumor-promoting activity on two-stage carcinogenesis test of mouse hepatic tumor using N-nitrosodiethylamine (DEN) as an initiator and phenobarbital (PB) as a promoter. Further, MR2 exhibited the remarkable inhibitory effect on two-stage carcinogenesis test of mouse skin induced by nitric oxide (NO) donor/12-O-tetradecanoylphorbol-13-acetate (TPA) or peroxynitrite/TPA.

Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Female; Focal Nodular Hyperplasia; Ginsenosides; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Mice, Inbred SENCAR; Nitrates; Nitro Compounds; Panax; Papilloma; Phenobarbital; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vietnam

1999