maitotoxin and allyl-alcohol

maitotoxin has been researched along with allyl-alcohol* in 1 studies

Other Studies

1 other study(ies) available for maitotoxin and allyl-alcohol

Article	Year
Synthesis and biological activity of the C'D'E'F' ring system of maitotoxin. The Journal of organic chemistry, 2014, Jun-06, Volume: 79, Issue:11 Stereoselective synthesis of the C'D'E'F' ring system of maitotoxin was achieved starting from the E' ring through successive formation of the D' and C' rings based on SmI2-mediated reductive cyclization. Construction of the F' ring was accomplished via Suzuki-Miyaura cross-coupling with a side chain fragment and Pd(II)-catalyzed cyclization of an allylic alcohol. The C'D'E'F' ring system inhibited maitotoxin-induced Ca(2+) influx in rat glioma C6 cells with an IC50 value of 59 μM. Topics: Animals; Catalysis; Cyclization; Inhibitory Concentration 50; Marine Toxins; Molecular Structure; Oxocins; Palladium; Polycyclic Compounds; Propanols; Rats; Stereoisomerism	2014

Article

Year

Synthesis and biological activity of the C'D'E'F' ring system of maitotoxin.

The Journal of organic chemistry, 2014, Jun-06, Volume: 79, Issue:11

Stereoselective synthesis of the C'D'E'F' ring system of maitotoxin was achieved starting from the E' ring through successive formation of the D' and C' rings based on SmI2-mediated reductive cyclization. Construction of the F' ring was accomplished via Suzuki-Miyaura cross-coupling with a side chain fragment and Pd(II)-catalyzed cyclization of an allylic alcohol. The C'D'E'F' ring system inhibited maitotoxin-induced Ca(2+) influx in rat glioma C6 cells with an IC50 value of 59 μM.

Topics: Animals; Catalysis; Cyclization; Inhibitory Concentration 50; Marine Toxins; Molecular Structure; Oxocins; Palladium; Polycyclic Compounds; Propanols; Rats; Stereoisomerism

2014