magnolol has been researched along with honokiol in 196 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (5.10) | 18.7374 |
| 1990's | 20 (10.20) | 18.2507 |
| 2000's | 61 (31.12) | 29.6817 |
| 2010's | 83 (42.35) | 24.3611 |
| 2020's | 22 (11.22) | 2.80 |
| Authors | Studies |
|---|---|
| Kuribara, H; Maruyama, Y; Morita, M; Weintraub, ST; Yuzurihara, M | 1 |
| Kong, ZL; Liu, YC; Tzeng, SC | 1 |
| Amblard, F; Arbiser, JL; Delinsky, D; Schinazi, RF | 1 |
| Amblard, F; Arbiser, JL; Detorio, M; Govindarajan, B; Lefkove, B; Rapp, KL; Schinazi, RF | 1 |
| Chang, ST; Chien, SC; Hou, CC; Hsiao, PW; Jan, JT; Kuo, CJ; Kuo, YH; Lee, CK; Lee, SS; Liang, PH; Liu, HG; Shyur, LF; Wang, SY; Wen, CC; Yang, NS | 1 |
| Bae, KH; Chang, MJ; Chen, QC; Jin, WY; Kim, HJ; Lee, IS; Lee, JP; Min, BS; Youn, UJ | 1 |
| Asakawa, Y; Echigo, N; Gomi, Y; Hashimoto, T; Hatakeyama, D; Ishikawa, T; Iwai, Y; Kuzuhara, T; Murakami, K; Okuno, Y | 1 |
| Baburin, I; Ecker, GF; Hering, S; Huefner, A; Schuehly, W; Taferner, B; Wiesner, K | 1 |
| Altmann, KH; Anavi-Goffer, S; Gertsch, J; Huefner, A; Kleyer, J; Paredes, JM; Raduner, S; Schuehly, W | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Kang, SS; Kim, WK; Lee, MA; Lee, SK; Park, HJ | 1 |
| Fuchs, A; Hinz, S; Karcz, T; Koetter, U; Lehr, M; Müller, CE; Rempel, V | 1 |
| Dong, G; Liu, N; Sheng, C; Wang, Y; Wu, S | 1 |
| Chen, K; Chen, L; Fu, S; Li, D; Liu, Z; Peng, A; Tang, H; Tang, M; Wan, L; Xue, L; Ye, H; Zhang, Y | 1 |
| Chen, A; Hu, A; Lin, D; Liu, J; Peng, J; Wu, X; Yan, Z; Ye, J | 1 |
| Sheng, J; Yu, Q | 1 |
| Hu, M; Tang, X; Zhao, Z | 1 |
| Feng, L; Han, G; Yang, J | 1 |
| Zhang, GD | 1 |
| Cui, JF; Song, WZ; Zhang, GD | 1 |
| Hou, YM; Li, Z; Lin, X; Zhang, M | 1 |
| Li, AJ | 1 |
| Chen, CC; Chen, YP; Hsu, HY; Huang, TF; Ko, FN; Lee, LG; Teng, CM | 1 |
| Fujimura, H; Matsuda, H; Miki, S; Yamahara, J | 1 |
| Chen, JM; Ji, CY; Song, WZ | 1 |
| Goto, Y; Hagino, K; Watanabe, H; Watanabe, K; Yamaguchi, M; Yamamoto, N | 1 |
| Hagino, K; Watanabe, H; Watanabe, K | 1 |
| Cheng, DC; Liu, JW | 1 |
| Chen, CF; Lee, TF; Tsai, TH; Wang, LC; Westly, J | 1 |
| Chen, CF; Chou, CJ; Tsai, TH | 1 |
| Homma, M; Itoh, H; Niitsuma, T; Oka, K | 1 |
| Chen, CC; Chen, CF; Hong, CY; Lo, YC; Teng, CM | 1 |
| Kawai, T; Kinoshita, K; Koyama, K; Takahashi, K | 1 |
| Fujii, I; Kuroyanagi, M; Miwa, M; Sugatani, J; Suzuki, Y; Ueno, A; Umehara, K; Yamazaki, R | 1 |
| Asaka, N; Hayashi, Y; Hirose, Y; Momma, N; Ohsawa, K; Tanaka, I; Ueda, J; Yasuda, T | 1 |
| Momma, N; Ohsawa, K; Ueda, J | 1 |
| Chang, Z; Zhou, F | 1 |
| Fukuda, A; Haraguchi, H; Ishikawa, H; Shirataki, N | 1 |
| Bae, K; Chang, B; Chung, C; Ku, Y; Lee, Y | 1 |
| Hong, CY; Huang, CH; Huang, SS; Hung, LM; Tsai, SK | 1 |
| Ai, J; Kahnberg, P; Nielsen, M; Saederup, E; Squires, RF; Sterner, O; Witt, MR | 1 |
| Bae, KH; Bang, KH; Kim, YK; Lee, JP; Min, BS; Na, MK; Rhee, YH | 1 |
| Kashimoto, T; Tachikawa, E; Takahashi, M | 1 |
| Lee, HJ; Ryu, JH; Son, HJ; Yun-Choi, HS | 1 |
| Chao, PD; Chen, SY; Hou, YC | 1 |
| Chen, CP; Ho, KY; Huang, JS; Lin, CC; Tsai, CC | 1 |
| Ai, J; Nielsen, M; Wang, X | 1 |
| Hu, X; Kuang, L; Li, F; Pan, Z; Wu, Z; Zhang, G | 1 |
| Ikeda, K; Nagase, H; Sakai, Y | 1 |
| Hattori, N; Ikarashi, Y; Maruyama, Y; Nakai, Y; Sakakibara, I; Yuzurihara, M | 1 |
| Liu, Y; Lu, J; Pei, X; Tang, C | 1 |
| Si, JP; Tong, ZK; Zeng, YR | 1 |
| Du, K; Wang, JX; Yuan, C; Zhu, LQ | 1 |
| Bae, K; Kim, YH; Lee, BH; Na, M; Park, EJ; Sohn, DH; Zhao, YZ | 1 |
| Pan, X; Si, J; Tong, Z; Zeng, Y | 1 |
| Pan, X; Si, J; Tong, Z; Zeng, Y; Zhu, Y | 1 |
| Si, J | 1 |
| Jiang, X; Liu, R; Si, J; Tong, Z; Zeng, Y | 1 |
| Chan, MH; Chen, HH; Ko, CH; Lin, YR | 4 |
| Fukuyama, Y; Mitsumoto, Y; Nakade, K; Zhai, H | 1 |
| Chan, MH; Chen, HH; Ko, CH; Lin, YR; Lu, YC | 1 |
| Geng, Y; Li, F; Wang, X; Wang, Y; Zheng, C | 1 |
| Jung, E; Jung, K; Kim, J; Kim, K; Lee, J; Park, B; Park, D; Park, E; Park, J; Park, Y | 1 |
| Fong, WF; Poon, KH; Tse, AK; Wang, C | 1 |
| Jifang, S; Jun, L; Miaoquan, L; Xihong, X; Yingyan, L | 1 |
| Hakamata, H; Jin, D; Kojima, S; Kotani, A; Kusu, F | 1 |
| Hong, S; Jung, E; Jung, K; Kim, J; Lee, J; Lee, S; Park, D; Park, E; Park, J; Park, S | 1 |
| Cao, H; Li, Y; Sun, QS; Tian, F; Wang, MW; Wang, XQ; Zhang, WW | 1 |
| Guo, BL; Huang, WH; Si, JP | 1 |
| Hanawa, T; Ito, G; Koyama, H; Oikawa, T | 1 |
| Chen, X; Fan, L; Hu, Z; Liu, L; Wu, X | 1 |
| Lu, Y; Pan, Y; Sun, C | 1 |
| Lin, LC; Tsai, TH; Wu, YT | 1 |
| Chen, G; Xu, X; Yang, P; Zhang, L; Zhu, Y | 1 |
| Chen, G; Xu, X; Yang, P; Yao, X | 1 |
| Aggarwal, BB; Ahn, KS; Arbiser, JL; Sethi, G; Shishodia, S; Sung, B | 1 |
| Li, K; Su, W; Yuan, J | 1 |
| Chen, L; Fan, L; Fisher, D; Garrard, I; Ignatova, S; Sutherland, IA; Tang, J; Yang, G; Zhang, Q | 1 |
| Chang, HT; Chang, PL; Chen, CL; Kuo, CH; Lee, SS; Peng, FC | 1 |
| Han, J; Wang, WZ; Wu, LZ; Zhang, P; Zheng, P | 1 |
| Ke, XH; Lin, SF; Wei, G | 1 |
| Feng, J; Li, JY; Zhou, XD | 1 |
| Chen, J; Li, N; Roberts, A; Song, Y; Wang, W; Wong, AW; Zhang, W | 1 |
| Bae, EA; Bae, KH; Han, SJ; Kim, DH; Trinh, HT; Yang, JH; Youn, UJ | 1 |
| Kong, LD; Li, JM; Li, YC; Pan, Y; Wang, CP; Wang, X; Xu, Q; Yi, LT | 1 |
| Dong, H; Liu, Y; Song, R; Tian, Y; Xu, F; Zhang, Z | 1 |
| Chan, SS; Che, CT; Fong, HH; Lao, L; Zhao, M | 1 |
| Lan, XQ; Liao, CL; Lin, XM; Shi, L; Yang, HB; Zhan, YH | 1 |
| Chen, S; Gu, X; Huang, X; Qin, F; Ren, P; Zhang, H | 1 |
| Guo, BL; Jiang, YF; Lv, D; Si, JP; Tong, ZK; Zhu, YQ | 1 |
| Bae, BK; Choi, GJ; Choi, JE; Choi, NH; Choi, YH; Jang, KS; Kang, MS; Kim, JC; Min, BS; Park, MS | 1 |
| Kapoor, S | 1 |
| Chung, YS; Kim, YC; Lee, BH; Shin, YK; Yin, HQ | 1 |
| He, S; Lei, ZJ; Zhang, SY; Zhang, ZY | 1 |
| Chávez-Avila, VM; Chivez, M; Cruz-Sosa, F; Domínguez, F; Garduñ-Ramírez, ML; Mata, M | 1 |
| Kong, LD; Pan, Y; Qiang, LQ; Wang, CP; Wang, FM; Yi, LT; Zhang, X | 1 |
| Chan, MH; Chen, HH; Ko, CH; Lin, YC; Lin, YR | 1 |
| He, S; Lei, Z; Xu, F; Zhang, S; Zhang, Z | 1 |
| Chávez, M; Chávez-Avila, VM; Cruz-Sosa, F; Domínguez, F; Garduño-Ramírez, ML; Mata, M | 1 |
| Wang, X; Zhang, L | 1 |
| Kunert, O; Schuehly, W; Teppner, H; Voith, W | 1 |
| Chen, L; He, S; Li, S; Peng, A; Shi, J; Ye, H; Zhong, S | 1 |
| Hu, Y; Li, H; Wang, X | 1 |
| Chen, DC; Chen, WC; Chen, YH; Cheng, YW; Chou, MC; Huang, PH; Liu, PL; Man, KM; Shen, JL | 1 |
| Baum, L; Chow, AH; Ho, YP; Hoi, CP | 1 |
| Alonso-Castro, AJ; Domínguez, F; García-Carrancá, A; Salazar-Olivo, LA; Zapata-Bustos, R | 1 |
| Liu, ZQ; Zhao, C | 1 |
| Alonso-Castro, AJ; Domínguez, F; Garcia-Carranca, A; Gonzalez-Espindola, LA; Gonzalez-Martinez, Mdel R; Jacobo-Salcedo, Mdel R | 1 |
| Fu, S; Ren, Y; Sun, C; Tao, X | 1 |
| Chakravarty, S; Chandrasekhar, S; Gajendra Reddy, R; Grée, R; Praveen Kumar, V; Vo, DD | 1 |
| Gao, Y; Han, P; Liu, H; Luan, F; Yan, X | 1 |
| Alexeev, M; Fisher, JL; Grosenbaugh, DK; Mott, DD | 1 |
| Cheng, Z | 1 |
| Chen, GY; Gong, HL; Huang, X; Tang, WF; Wang, J | 1 |
| Han, HK; Van Anh, LT | 1 |
| Li, MM; Shi, L; Yang, HB; Yu, JJ | 1 |
| Al-Suwayeh, SA; Fang, JY; Huang, YL; Hung, YY; Hwang, TL; Lin, CF | 1 |
| Chen, Q; Hou, X; Wang, S; Yuan, X; Zhang, B | 1 |
| Lee, JY; Lee, T; Park, SH; Song, KS; Yang, EJ | 1 |
| Li, YL; Liang, N; Luo, HJ; Wang, GC; Wu, X; Yang, XX; Yang, YT | 1 |
| Chen, HC; Hwang, TL; Kuo, PC; Lee, EJ; Lee, KH; Shih, HC; Wu, TS | 1 |
| Cha, BY; Choi, MS; Jung, UJ; Kim, SR; Kim, YJ; Park, YB; Woo, JT | 1 |
| Chilampalli, C; Dwivedi, C; Fahmy, H; Hildreth, MB; Kaushik, RS; Young, A; Zeman, D; Zhang, X | 1 |
| Deng, KY; Liu, HY; Peng, T; Yu, JW; Zhu, BY | 1 |
| Alonso-Castro, AJ; Cerbón, MA; Domínguez, F; García-Carrancá, A; García-Regalado, A; González-Sánchez, I | 1 |
| Cai, D; Cong, H; Hong, B; Li, G; Liu, J; Mu, G; Zhang, Q | 1 |
| Liu, S; Liu, Y; Liu, Z; Niu, X; Qi, Z; Wang, H; Wang, S; Xia, X | 1 |
| Li, N; Li, W; Sheng, YL; Shi, CH; Xu, HY; Xu, JH; Zhang, XR; Zhao, YQ | 1 |
| Cho, IJ; Jang, EJ; Jegal, KH; Jung, JY; Kang, SH; Kim, SC; Kim, YW; Ku, SK; Lee, JH; Lee, JR; Moon, SY; Park, SJ; Zhao, RJ | 1 |
| Hong, YS; Huo, Q; Lee, JK; Li, HM; Liu, H; Ma, T; Wu, CZ; Zhao, SR | 1 |
| Fan, T; He, L; Hu, J; Zhang, L | 1 |
| Gao, CF; Hu, J; Li, C; Ma, L; Rajput, NA; Wang, MH; Xiao, Y; Yang, J; Ye, YH; Zhang, YY | 1 |
| Baur, R; Fuchs, A; Müller, CE; Schoeder, C; Sigel, E | 1 |
| Coppola, M; Mondola, R | 1 |
| Ernst, M; Mihovilovic, MD; Puthenkalam, R; Rycek, L; Schnürch, M | 1 |
| Choi, EJ; Jun, SY; Kang, SH; Kim, HI; Kim, JA; Kim, Y; Park, DJ; Shin, OS; Son, SJ | 1 |
| Liao, K; Sun, L; Wang, D | 1 |
| Akae, H; Akagi, M; Akagi, R; Fukuishi, N; Fukuyama, Y; Hirashima, N; Matsui, N | 1 |
| Deng, Y; Han, X; Kang, J; Tan, Z; Tang, S; Wang, M; Xiao, W; Zhou, C | 1 |
| Lai, R; Liu, T; Pan, Y | 1 |
| Guo, M; Liang, J; Meng, J; Wu, D; Wu, S | 1 |
| Feng, F; Liu, Y; Shi, Q; Wang, D; Yang, G | 1 |
| Bian, ZX; Han, QB; Ho, HM; Hu, DD; Huang, T; Li, YH; Lin, CY; Lin, SH; Mi, H; Tan, HS; Xu, HX; Zhang, M; Zhao, L; Zhong, LL | 1 |
| Cheng, B; Guo, C; Huang, K; Ma, L; Peng, A; Zhao, Y; Zheng, L; Zhou, Q | 1 |
| Jahng, KY; Jeong, SI; Kim, J; Kim, SY; Yu, KY | 1 |
| Amorati, R; Baschieri, A; Valgimigli, L; Zotova, J | 1 |
| Xu, H; Yang, C; Zhi, X | 1 |
| Domon, H; Fukuyama, Y; Kubo, M; Oda, M; Okiji, T; Sakaue, Y; Takenaka, S; Terao, Y | 1 |
| Guo, X; Huo, Q; Jin, W; Li, H; Li, J; Li, N; Ma, T; Wu, C | 1 |
| Han, J; Li, YQ; Wang, GC; Zhang, XJ; Zuo, GY | 1 |
| Antoine, MH; Bunel, V; Duez, P; Nortier, J; Stévigny, C | 1 |
| Guo, LP; Ming, MD; Shi, L; Yang, HB; Zhang, CC; Zhu, SD | 1 |
| Wu, JG; Wu, JY; Wu, YB; Yi, J | 1 |
| Chen, JY; Chen, Y; Cheng, YC; Huang, HY; Hueng, DY | 1 |
| Hu, H; Hua, W; Wang, Z; You, Y; Zou, L | 1 |
| Chen, X; Hao, K; Hu, Y; Shan, L; Wang, GX; Yu, X | 1 |
| Baccarin, J; Corkery, JM; Guarino, V; Orsolini, L; Papanti, DG; Schifano, F | 1 |
| Chen, H; Chen, YL; Gao, WY; Jin, ZX; Wang, L; Wang, SP; Zhang, JZ | 1 |
| Basoli, V; Carta, P; Cruciani, S; Delogu, G; Dettori, MA; Fabbri, D; Maioli, M; Serra, PA | 1 |
| Liu, W; Zhu, X | 1 |
| Deng, Y; Han, X; Li, C; Tan, Z; Tang, S; Xiao, W | 1 |
| Hong, SH; Kim, BK; Kim, DD; Kim, KS; Kim, SB; Park, JW; Ryu, HM; Yoon, IS | 1 |
| Diomede, L; Kirika, N; Romeo, M; Salmona, M; Sarrica, A | 1 |
| Hosokawa, I; Hosokawa, Y; Matsuo, T; Ozaki, K | 1 |
| Bernaskova, M; Hufner, A; Miller, GW; Schuehly, W; Stout, K | 1 |
| Huang, Y; Li, S; Liu, C; Liu, S; Liu, Z; Wang, Y | 1 |
| Chen, L; Hewitson, P; Ignatova, S; Peng, A; Sutherland, I | 1 |
| Fu, Q; Guo, K; Shi, S; Tong, C; Xiao, Y; Xu, J | 1 |
| An, DR; Chen, YH; Guo, DS; Lu, MH; Miao, D; Yuan, CH; Yue, JY; Zhai, YY; Zhao, MM | 1 |
| Balmas, V; Carta, P; Delogu, G; Dettori, MA; Fabbri, D; Malbrán, I; Migheli, Q; Oufensou, S; Pani, G; Scherm, B | 1 |
| Hiratsuka, A; Izawa, T; Masuda, Y; Nishiyama, T; Ogura, K; Ohnuma, T | 1 |
| Teng, X; Wang, S; Wang, Y; Yuan, Y; Zhou, X | 1 |
| Copmans, D; de Witte, P; Hunyadi, B; Li, J; Luyten, W; Partoens, M | 1 |
| Bennett, B; Bui, D; Cheng, G; Feng, L; Hu, M; Kalyanaraman, B; Kim, YH; Myers, CR; Pan, J; Schmainda, K; Shin, SS; Wang, Y; Xiong, D; You, M; Zhang, Q; Zielonka, J | 1 |
| Chen, J; Li, D; Lv, B; Qin, S; Wang, D; Xu, D; Xu, F; Zhang, W; Zhang, Y; Zhang, Z | 1 |
| Fulczyk, A; Kowalska, T; Móricz, ÁM; Ott, PG; Sajewicz, M; Łata, E | 1 |
| Chen, P; Hu, Y; Zhang, H; Zhou, J | 1 |
| Chiu, KC; Hsia, SM; Jhuang, HS; Lan, WC; Li, PJ; Shen, YW; Shieh, TM; Shih, YH; Wang, TH; Yuan-Chien Chen, M | 1 |
| Chu, C; Jiang, L; Li, J; Liu, C; Wang, S; Weng, L; Yan, J; Zhang, H | 1 |
| Feng, Y; Guo, J; Guo, M; Liu, Y; Ren, C; Tan, Y; Wang, J; Wu, X | 1 |
| Cai, Y; Cao, Y; Chai, Y; Chen, L; Chen, X; Hong, Z; Liu, Y; Shi, Y; Wang, D; Zhu, Z | 1 |
| An, J; Dong, Z; Guo, C; He, C | 1 |
| Abbaszadeh, H; Mottaghi, S | 1 |
| Chen, SY; Hou, YC; Li, PY; Lin, SP; Yu, CP | 1 |
| Bai, G; Gao, J; Jiang, M; Niu, L; Shen, F; Wang, J | 1 |
| Cao, Y; Dai, X; Li, X; Liang, Y; Liu, K; Lu, J; Wang, X; Xie, L; Zhang, X | 1 |
| Kalyanaraman, B | 1 |
| Hou, L; Kang, L; Li, H; Nan, T; Rong, P; Sun, J; Wang, W; Yang, B; Yang, W; Zhang, J | 1 |
| Biotti, G; Budriesi, R; Buzzi, R; Corazza, I; Fontana, R; Frosini, M; Gotti, R; Manfredini, S; Marconi, P; Mattioli, LB; Micucci, M; Vertuani, S | 1 |
| Cardullo, N; Di Francesco, A; Muccilli, V; Pulvirenti, L; Sciacca, C | 1 |
| Feng, YF; Hu, ZQ; Ming-Xin Guo, MM; Wu, X | 1 |
| Fan, XC; Lu, TL; Mao, CQ; Qi, YF; Su, YA; Wang, SC; Zhang, KW | 1 |
| He, X; Wang, S; Wei, F; Zhang, M | 1 |
12 review(s) available for magnolol and honokiol
| Article | Year |
|---|---|
Tackling Fungal Resistance by Biofilm Inhibitors.
Topics: Animals; Antifungal Agents; Biofilms; Drug Discovery; Drug Resistance, Fungal; Fungi; Humans; Models, Molecular; Mycoses; Small Molecule Libraries | 2017 |
[A brief review of chemical studies of the medicinal plant houpo].
Topics: Alkaloids; Biphenyl Compounds; Chromatography; Drugs, Chinese Herbal; Lignans; Oils, Volatile | 1989 |
Honokiol and magnolol as multifunctional antioxidative molecules for dermatologic disorders.
Topics: Antioxidants; Biphenyl Compounds; Dermatologic Agents; Drugs, Chinese Herbal; Humans; Lignans; Skin Diseases | 2010 |
Nonpeptide neurotrophic agents useful in the treatment of neurodegenerative diseases such as Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Biphenyl Compounds; Cells, Cultured; Dietary Supplements; Hippocampus; Humans; Lignans; Magnolia; Mice; Molecular Weight; Nerve Growth Factors; Neurodegenerative Diseases; Neurogenesis; Phytotherapy; Polyphenols; Rats; Structure-Activity Relationship; Zingiberales | 2015 |
Advances on Semisynthesis, Total Synthesis, and Structure-Activity Relationships of Honokiol and Magnolol Derivatives.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Cell Line; Humans; Isomerism; Lignans; Magnolia; Plant Bark; Structure-Activity Relationship | 2016 |
Is there a potential of misuse for Magnolia officinalis compounds/metabolites?
Topics: Biphenyl Compounds; Humans; Lignans; Magnolia; Plant Bark; Plant Extracts; Substance-Related Disorders | 2017 |
Safety and Toxicology of Magnolol and Honokiol.
Topics: Animals; Biphenyl Compounds; Drug Interactions; Humans; Lignans; Magnolia; Mutagenicity Tests; Plant Extracts; Tissue Distribution | 2018 |
Cardiovascular Modulating Effects of Magnolol and Honokiol, Two Polyphenolic Compounds from Traditional Chinese Medicine-Magnolia Officinalis.
Topics: Biphenyl Compounds; Humans; Lignans; Magnolia; Medicine, Chinese Traditional | 2020 |
Natural Lignans Honokiol and Magnolol as Potential Anticarcinogenic and Anticancer Agents. A Comprehensive Mechanistic Review.
Topics: Antineoplastic Agents; Biphenyl Compounds; Humans; Lignans | 2022 |
The Neuropharmacological Effects of Magnolol and Honokiol: A Review of Signal Pathways and Molecular Mechanisms.
Topics: Biphenyl Compounds; Humans; Lignans; Signal Transduction | 2023 |
Exploiting the tumor immune microenvironment and immunometabolism using mitochondria-targeted drugs: Challenges and opportunities in racial disparity and cancer outcome research.
Topics: Atovaquone; Biphenyl Compounds; Black People; Health Status Disparities; Hispanic or Latino; Humans; Immune Checkpoint Inhibitors; Lignans; Mitochondria; Neoplasms; Oxidative Phosphorylation; Tumor Microenvironment | 2022 |
Research Progress on the Structural Modification of Magnolol and Honokiol and the Biological Activities of Their Derivatives.
Topics: Biphenyl Compounds; Lignans; Magnolia; Structure-Activity Relationship | 2023 |
184 other study(ies) available for magnolol and honokiol
| Article | Year |
|---|---|
Identification of magnolol and honokiol as anxiolytic agents in extracts of saiboku-to, an oriental herbal medicine.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Biphenyl Compounds; Drugs, Chinese Herbal; Lignans; Male; Medicine, Kampo; Mice; Mice, Inbred Strains; Plant Extracts | 1998 |
Cytotoxic neolignans: an SAR study.
Topics: Antineoplastic Agents; Biphenyl Compounds; Cell Line, Tumor; Humans; Lignans; Structure-Activity Relationship | 2005 |
Facile purification of honokiol and its antiviral and cytotoxic properties.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antiviral Agents; Biphenyl Compounds; Cell Line, Tumor; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lignans; Vero Cells | 2006 |
Synthesis, cytotoxicity, and antiviral activities of new neolignans related to honokiol and magnolol.
Topics: Antineoplastic Agents; Antiviral Agents; Biphenyl Compounds; HIV-1; Lignans; Molecular Structure | 2007 |
Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus.
Topics: Animals; Betulinic Acid; Cell Proliferation; Chlorocebus aethiops; Coronavirus 3C Proteases; Cysteine Endopeptidases; Lignans; Models, Molecular; Pentacyclic Triterpenes; Plants, Medicinal; Severe acute respiratory syndrome-related coronavirus; Structure-Activity Relationship; Terpenes; Triterpenes; Vero Cells; Viral Proteins; Virus Replication | 2007 |
Cytotoxic lignans from the stem bark of Magnolia officinalis.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Inhibitory Concentration 50; Korea; Lignans; Magnolia; Molecular Structure; Plant Bark; Plant Stems; Plants, Medicinal | 2007 |
Anti-influenza activity of marchantins, macrocyclic bisbibenzyls contained in liverworts.
Topics: Animals; Antiviral Agents; Cells, Cultured; Computer Simulation; Dogs; Endonucleases; Hepatophyta; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Kidney; Macrocyclic Compounds; Orthomyxoviridae Infections; Phytotherapy | 2011 |
Modulation of GABAA-receptors by honokiol and derivatives: subtype selectivity and structure-activity relationship.
Topics: Animals; Biphenyl Compounds; Lignans; Models, Molecular; Oocytes; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis | 2011 |
Mechanisms of osteoclastogenesis inhibition by a novel class of biphenyl-type cannabinoid CB(2) receptor inverse agonists.
Topics: Animals; Biphenyl Compounds; Calcium; Cannabinoid Receptor Modulators; Cell Line; Cell Migration Inhibition; Cells, Cultured; Cyclic AMP; Humans; Lignans; Macrophages; Mice; Monocytes; Osteoclasts; Osteogenesis; Plant Extracts; Plants; Receptor, Cannabinoid, CB2; Tumor Necrosis Factor-alpha | 2011 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Anti-proliferative activity of hydnocarpin, a natural lignan, is associated with the suppression of Wnt/β-catenin signaling pathway in colon cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Axin Protein; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Flavonolignans; Humans; Lignans; Lonicera; RNA Interference; RNA, Small Interfering; Wnt Proteins; Wnt Signaling Pathway | 2013 |
Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55.
Topics: | 2013 |
Discovery and synthesis of novel magnolol derivatives with potent anticancer activity in non-small cell lung cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Female; Human Umbilical Vein Endothelial Cells; Humans; Lignans; Lung Neoplasms; Magnolia; Mice, Inbred BALB C; Mice, Nude; Xenograft Model Antitumor Assays | 2018 |
Anti-proliferative activity and structure-activity relationship of honokiol derivatives.
Topics: Biphenyl Compounds; Humans; Lignans; Structure-Activity Relationship | 2019 |
[Determination of magnolol and honokiol in different processed samples of houpo by HPLC method].
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hot Temperature; Lignans; Technology, Pharmaceutical | 1992 |
[Determination of magnolol and honokiol in 3 species of houpo (corter Magnoliae) of different ages by HPLC].
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lignans; Plants, Medicinal; Quality Control; Species Specificity; Time Factors | 1992 |
[Quality standard of kaixiong shunqi pills].
Topics: Biphenyl Compounds; Chromatography, Thin Layer; Densitometry; Drug Combinations; Drugs, Chinese Herbal; Lignans; Quality Control | 1991 |
[Studies on the medicinal plants of Magnoliaceae tu-hou-po of Manglietia].
Topics: Biphenyl Compounds; Drugs, Chinese Herbal; Isoquinolines; Lignans; Neuromuscular Nondepolarizing Agents; Plants, Medicinal | 1989 |
[A study of the quality of Fujian native Magnolia officinalis Rehd. et Wils. var. biloba Rehd. et Wils].
Topics: Biphenyl Compounds; Lignans; Plants, Medicinal; Quality Control; Time Factors | 1989 |
[Determination of magnolod and honokiol in different parts of Magnolia officinalis and the effect of processing on their content].
Topics: Biphenyl Compounds; Hot Temperature; Lignans; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Plants, Medicinal; Tissue Distribution | 1985 |
Two antiplatelet agents from Magnolia officinalis.
Topics: Animals; Biphenyl Compounds; Calcium; In Vitro Techniques; Lignans; Medicine, Chinese Traditional; Platelet Aggregation Inhibitors; Platelet Function Tests; Rabbits; Thromboxane B2 | 1988 |
[Screening test for calcium antagonists in natural products. The active principles of Magnolia obovata].
Topics: Animals; Aorta, Thoracic; Biphenyl Compounds; Calcium Channel Blockers; In Vitro Techniques; Lignans; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Muscle Contraction; Muscle, Smooth, Vascular; Plants, Medicinal; Rats; Rats, Inbred Strains | 1986 |
[Studies on the medicinal plants of Magnoliaceae. II. Botanical origins and resource utilization of a Chinese drug "hou pu"].
Topics: Biphenyl Compounds; China; Lignans; Plants, Medicinal | 1984 |
Pharmacological properties of magnolol and honokiol extracted from Magnolia officinalis: central depressant effects.
Topics: Animals; Biphenyl Compounds; Central Nervous System Depressants; Chickens; Lignans; Male; Mice; Rats; Rats, Inbred Strains | 1983 |
Chemostructural requirement for centrally acting muscle relaxant effect of magnolol and honokiol, neolignane derivatives.
Topics: Animals; Biphenyl Compounds; Chemical Phenomena; Chemistry; Chickens; Eugenol; Lignans; Male; Mephenesin; Mice; Muscle Contraction; Muscle Relaxants, Central; Reflex; Spinal Cord; Structure-Activity Relationship | 1983 |
[Quantitative analysis of magnolol and honokiol in the bark of Magnolia officinalis Rehd et Wils and Magnolia rostrata WW Smith].
Topics: Biphenyl Compounds; China; Lignans; Plants, Medicinal | 1982 |
Effects of honokiol and magnolol on acetylcholine release from rat hippocampal slices.
Topics: Acetylcholine; Animals; Biphenyl Compounds; Central Nervous System Depressants; Hippocampus; In Vitro Techniques; Lignans; Rats; Rats, Sprague-Dawley | 1995 |
Glucuronidation of magnolol assessed using HPLC/fluorescence.
Topics: Animals; Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucuronidase; Lignans; Male; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1995 |
A novel 11 beta-hydroxysteroid dehydrogenase inhibitor contained in saiboku-to, a herbal remedy for steroid-dependent bronchial asthma.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Antineoplastic Agents, Phytogenic; Asthma; Biphenyl Compounds; Chromatography, High Pressure Liquid; Cortisone; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucocorticoids; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hydrocortisone; Hydroxysteroid Dehydrogenases; Immunosuppressive Agents; Lignans; Liver; Male; Medicine, Kampo; Rats; Rats, Wistar | 1994 |
Magnolol and honokiol isolated from Magnolia officinalis protect rat heart mitochondria against lipid peroxidation.
Topics: Animals; Antioxidants; Biphenyl Compounds; Lignans; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria, Heart; Oxygen Consumption; Phytotherapy; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Vitamin E | 1994 |
Anti-emetic principles of Magnolia obovata bark and Zingiber officinale rhizome.
Topics: Animals; Antiemetics; Anura; Biphenyl Compounds; Catechols; Fatty Alcohols; Female; Lignans; Male; Plants, Medicinal | 1994 |
Development of a novel method for determination of acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acetyltransferase activity and its application to screening for acetyltransferase inhibitors. Inhibition by magnolol and honokiol from Magnoliae cortex.
Topics: Acetyltransferases; Animals; Biphenyl Compounds; Humans; In Vitro Techniques; Lignans; Male; Plant Extracts; Rats; Rats, Wistar; Reproducibility of Results | 1994 |
[A simultaneous determination of honokiol and mangolol in Oriental pharmaceutical decoctions containing magnolia bark by ion-pair high-performance liquid chromatography. II].
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lignans | 1993 |
[A simultaneous determination of honokiol and magnolol in oriental pharmaceutical decoctions containing magnolia bark by ion-pair high-performance liquid chromatography].
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lignans | 1993 |
[Quantitative determination of magnolol and honokiol in baoji pill by HPLC].
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Gastrointestinal Agents; Lignans; Quality Control | 1995 |
Antiperoxidative activity of neolignans from Magnolia obovata.
Topics: Animals; Antioxidants; Biphenyl Compounds; Drugs, Chinese Herbal; Erythrocytes; Hemolysis; Lignans; Lipid Peroxidation; Male; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Wistar; Trees | 1997 |
Antimicrobial activity of magnolol and honokiol against periodontopathic microorganisms.
Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Biphenyl Compounds; Capnocytophaga; Cells, Cultured; Epithelial Cells; Fibroblasts; Gingiva; Humans; Lignans; Porphyromonas gingivalis; Prevotella; Veillonella | 1998 |
Antiarrhythmic effect of magnolol and honokiol during acute phase of coronary occlusion in anesthetized rats: influence of L-NAME and aspirin.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Aspirin; Biphenyl Compounds; Blood Pressure; Coronary Disease; Enzyme Inhibitors; Lignans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1999 |
Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.
Topics: Allosteric Regulation; Androstanes; Animals; Azasteroids; Binding Sites; Biphenyl Compounds; Cell Membrane; Central Nervous System Depressants; Cerebellum; Diflunisal; Drugs, Chinese Herbal; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Lignans; Muscimol; Picrotoxin; Propofol; Prosencephalon; Rats; Receptors, GABA-A; Tritium | 1999 |
Antifungal activity of magnolol and honokiol.
Topics: Antifungal Agents; Biphenyl Compounds; Humans; Lignans; Microbial Sensitivity Tests | 2000 |
Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells.
Topics: Acetylcholine; Adrenal Glands; Animals; Biphenyl Compounds; Calcium; Camphanes; Catecholamines; Cattle; Chromaffin Cells; In Vitro Techniques; Lignans; Magnoliopsida; Plant Extracts; Potassium; Sesquiterpenes, Eudesmane; Sodium; Terpenes | 2000 |
Inhibitors of nitric oxide synthesis and TNF-alpha expression from Magnolia obovata in activated macrophages.
Topics: Animals; Biphenyl Compounds; Blotting, Western; Cell Line; Enzyme Inhibitors; Lignans; Lipopolysaccharides; Macrophage Activation; Macrophages; Magnetic Resonance Spectroscopy; Magnoliopsida; Mice; Nitric Oxide; Nitric Oxide Synthase; Tumor Necrosis Factor-alpha | 2000 |
Honokiol and magnolol increased hippocampal acetylcholine release in freely-moving rats.
Topics: Acetylcholine; Animals; Biphenyl Compounds; Drugs, Chinese Herbal; Hippocampus; Lignans; Male; Rats; Rats, Sprague-Dawley | 2000 |
Antimicrobial activity of honokiol and magnolol isolated from Magnolia officinalis.
Topics: Actinobacillus; Anti-Bacterial Agents; Bacillus; Bacteria; Biphenyl Compounds; Drugs, Chinese Herbal; Humans; Lignans; Magnoliopsida; Microbial Sensitivity Tests; Micrococcus; Periodontal Diseases; Plants, Medicinal; Porphyromonas; Prevotella | 2001 |
Honokiol and magnolol selectively interact with GABAA receptor subtypes in vitro.
Topics: Animals; Biphenyl Compounds; Cell Line; Cerebellum; Drugs, Chinese Herbal; Flunitrazepam; GABA Agonists; GABA Modulators; Hippocampus; Humans; Insecta; Lignans; Male; Muscimol; Nitric Oxide Synthase; Protein Subunits; Rats; Rats, Wistar; Receptors, GABA-A; Recombinant Proteins; Tritium | 2001 |
[Quality control for huoxiang-zhengqi liquid].
Topics: Asteraceae; Biphenyl Compounds; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Citrus; Drug Combinations; Drugs, Chinese Herbal; Lignans; Magnoliopsida; Quality Control | 1998 |
Inhibitory effect of magnolol and honokiol from Magnolia obovata on human fibrosarcoma HT-1080. Invasiveness in vitro.
Topics: Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Fibrosarcoma; Humans; Lignans; Magnoliaceae; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Phytotherapy; Plant Bark; Tumor Cells, Cultured | 2001 |
Effects of the extract of the bark of Magnolia obovata and its biphenolic constituents magnolol and honokiol on histamine release from peritoneal mast cells in rats.
Topics: Animals; Biphenyl Compounds; Drugs, Chinese Herbal; Histamine H1 Antagonists; Histamine Release; Lignans; Magnoliaceae; Mast Cells; Medicine, Kampo; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Plant Bark; Plant Extracts; Rats | 2001 |
[Study on HPLC-FPS of cortex magnoliae officinalis].
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lignans; Magnoliaceae; Quality Control | 2002 |
[A study on bark quality of Magnolia officinalis Rehd. et Wils].
Topics: Biphenyl Compounds; Lignans; Magnolia; Plant Bark; Plants, Medicinal; Quality Control | 2000 |
[Simultaneous determination of magnolol and honokiol in serum and urine by high performance liquid chromatography].
Topics: Animals; Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lignans; Magnolia; Male; Platelet Aggregation Inhibitors; Rats; Rats, Wistar | 2000 |
Protective effects of honokiol and magnolol on tertiary butyl hydroperoxide- or D-galactosamine-induced toxicity in rat primary hepatocytes.
Topics: Animals; Biphenyl Compounds; Cells, Cultured; Galactosamine; Hepatocytes; Lignans; Liver; Male; Protective Agents; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide | 2003 |
[Study on the relationship between provenance, leaf type and quality in Magnolia officinalis].
Topics: Biphenyl Compounds; China; Chromatography, High Pressure Liquid; Lignans; Magnolia; Plant Leaves; Plants, Medicinal; Quality Control; Species Specificity | 1998 |
[A study on the relationship between tree age and bark quality in Magnolia officinalis].
Topics: Age Factors; Biphenyl Compounds; China; Chromatography, High Pressure Liquid; Lignans; Magnolia; Plant Bark; Plant Leaves; Plants, Medicinal | 1999 |
[Study on genuineness of traditional Chinese medicine cortex Magnoliae officinalis].
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lignans; Magnolia; Plant Leaves; Plants, Medicinal; Quality Control | 2000 |
[Quality evaluation and utilization of germplasm resources of Magnolia officinalis].
Topics: Biphenyl Compounds; China; Drugs, Chinese Herbal; Ecosystem; Lignans; Magnolia; Phenols; Plant Bark; Plants, Medicinal; Quality Control; Seeds; Species Specificity | 2002 |
Inhibition of smooth muscle contraction by magnolol and honokiol in porcine trachea.
Topics: Animals; Asthma; Biphenyl Compounds; Bronchodilator Agents; Calcium; Carbachol; Dose-Response Relationship, Drug; Lignans; Magnolia; Male; Muscle Contraction; Muscle, Smooth; Phytotherapy; Potassium Chloride; Swine; Trachea; Verapamil | 2003 |
Honokiol and magnolol induce Ca2+ mobilization in rat cortical neurons and human neuroblastoma SH-SY5Y cells.
Topics: Animals; Biphenyl Compounds; Calcium; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Female; Humans; Lignans; Neuroblastoma; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley | 2003 |
The mechanism of honokiol-induced and magnolol-induced inhibition on muscle contraction and Ca2+ mobilization in rat uterus.
Topics: Animals; Biphenyl Compounds; Calcium; Carbachol; Central Nervous System Depressants; Dinoprost; Female; Fluorescent Dyes; Fura-2; In Vitro Techniques; Lignans; Muscarinic Agonists; Myometrium; Oxytocics; Oxytocin; Potassium Chloride; Rats; Uterine Contraction; Uterus | 2003 |
Isolation and purification of honokiol and magnolol from cortex Magnoliae officinalis by high-speed counter-current chromatography.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Countercurrent Distribution; Lignans; Magnetic Resonance Spectroscopy; Magnolia | 2004 |
In vitro antibacterial and anti-inflammatory effects of honokiol and magnolol against Propionibacterium sp.
Topics: Adult; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Lignans; Microbial Sensitivity Tests; Propionibacterium; Skin Irritancy Tests | 2004 |
Magnolol and honokiol enhance HL-60 human leukemia cell differentiation induced by 1,25-dihydroxyvitamin D3 and retinoic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Calcitriol; Calcium Channel Agonists; CD11b Antigen; Cell Differentiation; G1 Phase; HL-60 Cells; Humans; Lignans; Lipopolysaccharide Receptors; MAP Kinase Signaling System; Resting Phase, Cell Cycle; Tretinoin | 2005 |
Effects of Magnolol and Honokiol on the activities of streptococcal glucosyltransferases both in solution and adsorbed on an experimental pellicle.
Topics: Adsorption; Biphenyl Compounds; Enzyme Inhibitors; Glucans; Glucosyltransferases; Lignans; Microspheres; Streptococcus | 2004 |
Determination of honokiol and magnolol by micro HPLC with electrochemical detection and its application to the distribution analysis in branches and leaves of Magnolia obovata.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Electrochemistry; Lignans; Magnolia; Medicine, Kampo; Microfluidics; Plant Components, Aerial; Plant Extracts; Plant Leaves | 2005 |
Anti-inflammatory effects of magnolol and honokiol are mediated through inhibition of the downstream pathway of MEKK-1 in NF-kappaB activation signaling.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biphenyl Compounds; Cytokines; Humans; Interleukin-8; Lignans; Magnolia; MAP Kinase Kinase Kinase 1; Microbial Sensitivity Tests; Monocytes; NF-kappa B; Phytotherapy; Picrates; Plant Extracts; Propionibacterium acnes; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2005 |
Differential inhibitory effects of honokiol and magnolol on excitatory amino acid-evoked cation signals and NMDA-induced seizures.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Calcium; Cells, Cultured; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ion Channels; Lignans; Mice; N-Methylaspartate; Neurons; Platelet Aggregation Inhibitors; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Sodium | 2005 |
Effects of magnolol and honokiol derived from traditional Chinese herbal remedies on gastrointestinal movement.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Drugs, Chinese Herbal; Female; Gastric Emptying; Gastrointestinal Agents; Gastrointestinal Motility; Guinea Pigs; Lignans; Male; Mice; Muscle, Smooth; Rats | 2005 |
[Studies on HPLC chromatogram of phenolic constituents of Cortex Magnoliae Officinalis].
Topics: Biphenyl Compounds; China; Chromatography, High Pressure Liquid; Ecosystem; Lignans; Magnolia; Plant Bark; Plants, Medicinal; Quality Control | 2005 |
Prokinetic effect of a Kampo medicine, Hange-koboku-to (Banxia-houpo-tang), on patients with functional dyspepsia.
Topics: Adult; Biphenyl Compounds; Catechols; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Dyspepsia; Fatty Alcohols; Female; Gastric Emptying; Humans; Lignans; Male; Medicine, Kampo; Middle Aged; Phytotherapy; Statistics, Nonparametric; Ultrasonography | 2005 |
Separation and determination of honokiol and magnolol in herbal medicines by flow injection-capillary electrophoresis.
Topics: Biphenyl Compounds; Buffers; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Electrophoresis, Capillary; Equipment Design; Herbal Medicine; Hydrogen-Ion Concentration; Lignans; Magnolia; Models, Chemical; Phosphates; Plant Extracts; Regression Analysis; Time Factors | 2006 |
A comparative study of upright counter-current chromatography and high-performance liquid chromatograpohy for preparative isolation and purification ofphenolic compounds from Magnoliae officinalis.
Topics: Biphenyl Compounds; Chromatography; Lignans; Magnetic Resonance Spectroscopy; Magnolia; Molecular Structure; Solvents | 2006 |
Simultaneous determination of honokiol and magnolol in Magnolia officinalis by liquid chromatography with tandem mass spectrometric detection.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Lignans; Magnolia; Mass Spectrometry; Molecular Structure; Plant Bark; Reproducibility of Results | 2006 |
Neuroprotective activity of honokiol and magnolol in cerebellar granule cell damage.
Topics: Animals; Antioxidants; Biphenyl Compounds; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hydrogen Peroxide; L-Lactate Dehydrogenase; Lignans; Mitochondria; N-Methylaspartate; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin E | 2006 |
Determination of honokiol and magnolol in cortex Magnoliae Officinalis by capillary electrophoresis with electrochemical detection.
Topics: Anti-Arrhythmia Agents; Biphenyl Compounds; Drugs, Chinese Herbal; Electrochemistry; Electrodes; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Lignans; Magnolia; Plant Bark; Regression Analysis | 2006 |
Carbon nanotube/poly(methyl methacrylate) composite electrode for capillary electrophoretic measurement of honokiol and magnolol in Cortex Magnoliae Officinalis.
Topics: Biphenyl Compounds; Catalysis; Drugs, Chinese Herbal; Electrodes; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Lignans; Magnolia; Nanotubes, Carbon; Polymethyl Methacrylate; Sensitivity and Specificity | 2006 |
Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway.
Topics: Animals; Apoptosis; Biphenyl Compounds; Carrier Proteins; Cyclin D1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Synergism; Genes, myc; Humans; I-kappa B Proteins; Lignans; Matrix Metalloproteinase 9; Membrane Glycoproteins; Membrane Proteins; Mice; Molecular Structure; NF-kappa B; NF-KappaB Inhibitor alpha; Osteoclasts; Osteogenesis; Phosphorylation; Promoter Regions, Genetic; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Synaptotagmin I; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2006 |
Determination of liquiritin, naringin, hesperidin, thymol, imperatorin, honokiol, isoimperatorin, and magnolol in the traditional Chinese medicinal preparation Huoxiang-zhengqi liquid using high-performance liquid chromatography.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Furocoumarins; Glucosides; Hesperidin; Lignans; Reproducibility of Results; Solutions; Thymol | 2006 |
Rapid purification and scale-up of honokiol and magnolol using high-capacity high-speed counter-current chromatography.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Countercurrent Distribution; Lignans; Pilot Projects | 2007 |
Analysis of magnolol and honokiol in biological fluids by capillary zone electrophoresis.
Topics: Animals; Biphenyl Compounds; Electrophoresis, Capillary; Fluorescence; Humans; Lignans; Microsomes, Liver; Rats; Reference Standards; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2007 |
[Optimization of preparative technique for banxia-houpu effervescent tablets by orthogonal design].
Topics: Biphenyl Compounds; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Citric Acid; Drugs, Chinese Herbal; Hydrogen-Ion Concentration; Lignans; Pinellia; Plants, Medicinal; Polyethylene Glycols; Sodium Bicarbonate; Tablets; Technology, Pharmaceutical | 2006 |
[Investigate into of effective constituent transference of herba Ephedrae and cortex Magnoliae officinalis in preparation course of Shujin Kechuan capsule].
Topics: Asthma; Biphenyl Compounds; Capsules; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Ephedra sinica; Ephedrine; Lignans; Magnolia; Plant Structures; Plants, Medicinal; Technology, Pharmaceutical | 2006 |
[Effects of the active compounds of M. officinalis on cariogenic bacteria].
Topics: Acids; Bacteria; Biofilms; Biphenyl Compounds; Dental Caries; Lignans; Magnolia; Plant Extracts | 2007 |
Evaluation of the in vitro and in vivo genotoxicity of magnolia bark extract.
Topics: Administration, Oral; Animals; Biphenyl Compounds; Bone Marrow Cells; Chromatography, High Pressure Liquid; Cyclophosphamide; Dose-Response Relationship, Drug; Escherichia coli; Female; Lignans; Magnolia; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mutagenicity Tests; Mutation; Plant Bark; Plant Extracts; Reproducibility of Results; Salmonella typhimurium | 2007 |
Effects of honokiol and magnolol on acute and inflammatory pain models in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Central Nervous System Depressants; Disease Models, Animal; Drug Evaluation, Preclinical; Fixatives; Formaldehyde; Inflammation; Lignans; Lumbosacral Region; Magnolia; Memory; Mice; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos | 2007 |
Magnolol and honokiol: inhibitors against mouse passive cutaneous anaphylaxis reaction and scratching behaviors.
Topics: Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Biphenyl Compounds; Cell Line, Tumor; Dose-Response Relationship, Drug; Immunoglobulin E; Inhibitory Concentration 50; Lignans; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Molecular Structure; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Pruritus; Rats | 2007 |
Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biphenyl Compounds; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exploratory Behavior; Hindlimb Suspension; Hydroxyindoleacetic Acid; Lignans; Magnolia; Male; Mice; Mice, Inbred ICR; Phytotherapy; Rats; Rats, Wistar; Serotonin; Stress, Physiological; Swimming | 2008 |
Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction.
Topics: Administration, Oral; Animals; Anthraquinones; Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Female; Lignans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2008 |
Magnolol and honokiol account for the anti-spasmodic effect of Magnolia officinalis in isolated guinea pig ileum.
Topics: Animals; Biphenyl Compounds; Guinea Pigs; Ileum; Lignans; Magnolia; Molecular Structure; Muscle Contraction; Muscle, Smooth; Plant Extracts | 2008 |
[Phenols in seedling cortex of Magnolia officinalis from Enshi].
Topics: Age Factors; Biphenyl Compounds; China; Chromatography, High Pressure Liquid; Lignans; Magnolia; Plant Bark; Plant Stems; Plants, Medicinal; Seedlings | 2008 |
Simultaneous determination of 12 chemical constituents in the traditional Chinese Medicinal Prescription Xiao-Yao-San-Jia-Wei by HPLC coupled with photodiode array detection.
Topics: Acetophenones; Benzoates; Biphenyl Compounds; Bridged-Ring Compounds; Coumaric Acids; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Hesperidin; Iridoids; Isoflavones; Lignans; Medicine, Chinese Traditional; Molecular Structure; Monoterpenes; Quality Control; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2008 |
[Effects of storage time on magnolol and honokiol contents in bark of Magnolia officinalis].
Topics: Biphenyl Compounds; Drug Storage; Drugs, Chinese Herbal; Lignans; Magnolia; Plant Bark; Time Factors | 2008 |
Effects of neolignans from the stem bark of Magnolia obovata on plant pathogenic fungi.
Topics: Allyl Compounds; Antifungal Agents; Biphenyl Compounds; Chromatography, Thin Layer; Fungi; Lignans; Magnolia; Microbial Sensitivity Tests; Mycelium; Phenyl Ethers; Plant Bark; Plant Diseases; Plant Extracts | 2009 |
Antineoplastic effects of Magnoliae officinalis in tumours other than hepatomas.
Topics: Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Humans; Lignans; Magnolia; Neoplasms; Plant Extracts | 2009 |
Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes.
Topics: Active Transport, Cell Nucleus; Animals; Biphenyl Compounds; Cell Line, Tumor; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; fas Receptor; Fatty Acids; Fatty Liver, Alcoholic; Genes, Reporter; Glutathione; Lignans; Lipogenesis; Liver; Male; Promoter Regions, Genetic; Protective Agents; Rats; Rats, Wistar; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic; Transfection; Triglycerides; Tumor Necrosis Factor-alpha | 2009 |
[Micronization of magnolia bark extract by RESS as well as dissolution and pharmacokinetics evaluation].
Topics: Administration, Oral; Animals; Area Under Curve; Biphenyl Compounds; Drug Compounding; Drugs, Chinese Herbal; Lignans; Magnolia; Male; Microspheres; Particle Size; Plant Bark; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Solubility | 2009 |
Production of honokiol and magnolol in suspension cultures of Magnolia dealbata Zucc.
Topics: Anti-Anxiety Agents; Antineoplastic Agents, Phytogenic; Biomass; Biphenyl Compounds; Carbohydrates; Cells, Cultured; Chromatography, High Pressure Liquid; Kinetics; Lignans; Magnolia; Mexico | 2009 |
Combined administration of the mixture of honokiol and magnolol and ginger oil evokes antidepressant-like synergism in rats.
Topics: Animals; Antidepressive Agents; Biphenyl Compounds; Brain; Cholecystokinin; Depression; Drug Synergism; Drug Therapy, Combination; Gastric Mucosa; Gastrins; Lignans; Male; Oils, Volatile; Rats; Rats, Wistar; Serotonin; Swimming; Zingiber officinale | 2009 |
Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain.
Topics: Analgesics; Animals; Anti-Infective Agents; Biphenyl Compounds; Dinoprostone; Excitatory Amino Acid Agents; Glycine; Immunohistochemistry; Inflammation; Lignans; Male; Mice; N-Methylaspartate; Phenylacetates; Proto-Oncogene Proteins c-fos; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2009 |
Micronization of magnolia bark extract with enhanced dissolution behavior by rapid expansion of supercritical solution.
Topics: Biphenyl Compounds; Calorimetry, Differential Scanning; Carbon Dioxide; Drugs, Chinese Herbal; Equipment Design; Lignans; Magnolia; Molecular Structure; Particle Size; Plant Bark; Solubility; Solutions; Spectrophotometry, Infrared; Technology, Pharmaceutical; Time Factors | 2010 |
Honokiol and magnolol production by in vitro micropropagated plants of Magnolia dealbata, an endangered endemic Mexican species.
Topics: Biphenyl Compounds; Conservation of Natural Resources; Culture Media; Lignans; Magnolia; Mexico; Plant Roots; Plant Shoots; Tissue Culture Techniques | 2010 |
Hydrophobic ionic liquid-based ultrasound-assisted extraction of magnolol and honokiol from cortex Magnoliae officinalis.
Topics: Biphenyl Compounds; Drugs, Chinese Herbal; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Imidazoles; Ionic Liquids; Lignans; Magnolia; Molecular Structure; Solvents; Ultrasonics | 2010 |
Substituted dineolignans from Magnolia garrettii.
Topics: Austria; Biphenyl Compounds; Lignans; Magnolia; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenyl Ethers; Plant Leaves | 2010 |
Separation of honokiol and magnolol by intermittent counter-current extraction.
Topics: Biphenyl Compounds; Chemical Fractionation; Countercurrent Distribution; Drugs, Chinese Herbal; Lignans; Models, Chemical | 2010 |
Distinct photoacidity of honokiol from magnolol.
Topics: Acids; Biphenyl Compounds; Hydrogen-Ion Concentration; Lignans; Magnetic Resonance Spectroscopy; Photochemistry; Spectrometry, Fluorescence | 2011 |
Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-amyloid-induced toxicity in PC12 cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Biphenyl Compounds; Calcium; Caspase 3; Cell Survival; Drugs, Chinese Herbal; Lignans; Magnolia; Neuroprotective Agents; PC12 Cells; Rats; Reactive Oxygen Species | 2010 |
Magnolia dealbata Zucc and its active principles honokiol and magnolol stimulate glucose uptake in murine and human adipocytes using the insulin-signaling pathway.
Topics: 3T3 Cells; 4-Chloro-7-nitrobenzofurazan; Adipocytes; Adipogenesis; Animals; Biphenyl Compounds; Cell Survival; Deoxyglucose; Drug Synergism; Glucose; Humans; Hypoglycemic Agents; Insulin; Lignans; Lipid Metabolism; Magnolia; Mice; Plant Extracts; Signal Transduction | 2011 |
Comparison of antioxidant abilities of magnolol and honokiol to scavenge radicals and to protect DNA.
Topics: Antioxidants; Biphenyl Compounds; DNA; Free Radical Scavengers; Lignans | 2011 |
Antimicrobial activity and cytotoxic effects of Magnolia dealbata and its active compounds.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Biphenyl Compounds; Fungi; Humans; Leukocytes, Mononuclear; Lignans; Magnolia; Plant Extracts | 2011 |
Anti-inflammatory effects of active constituents extracted from Chinese medicinal herbs against Propionibacterium acnes.
Topics: Anti-Inflammatory Agents; Biphenyl Compounds; Cell Line; Drugs, Chinese Herbal; Flavonoids; Humans; Interleukin-8; Keratinocytes; Lignans; Propionibacterium acnes; Triterpenes; Ursolic Acid | 2012 |
Synthesis and neurite growth evaluation of new analogues of honokiol, a neolignan with potent neurotrophic activity.
Topics: Animals; Biphenyl Compounds; Cells, Cultured; Humans; Immunohistochemistry; Lignans; Molecular Structure; Nerve Growth Factors; Neurites; Neurogenesis; Small Molecule Libraries; Structure-Activity Relationship | 2012 |
Separation and determination of honokiol and magnolol in Chinese traditional medicines by capillary electrophoresis with the application of response surface methodology and radial basis function neural network.
Topics: Biphenyl Compounds; Computational Biology; Drugs, Chinese Herbal; Electrophoresis, Capillary; Lignans; Magnolia; Models, Statistical; Neural Networks, Computer; Plant Bark; Reproducibility of Results | 2012 |
The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors.
Topics: Animals; Biphenyl Compounds; Drugs, Chinese Herbal; GABA Agents; HEK293 Cells; Hippocampus; Humans; Inhibitory Postsynaptic Potentials; Lignans; Neurons; Rats; Receptors, GABA-A; Synaptic Transmission | 2012 |
Comparative studies on the interactions of honokiol and magnolol with human serum albumin.
Topics: Biphenyl Compounds; Circular Dichroism; Humans; Hydrophobic and Hydrophilic Interactions; Lignans; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Static Electricity | 2012 |
Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction [See Text] in rats.
Topics: Administration, Oral; Animals; Anthraquinones; Biphenyl Compounds; Drug Incompatibility; Emodin; Flavanones; Hesperidin; Lignans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley | 2012 |
Modulation of P-glycoprotein expression by honokiol, magnolol and 4-O-methylhonokiol, the bioactive components of Magnolia officinalis.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biphenyl Compounds; Cell Line, Tumor; Daunorubicin; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lignans; Magnolia; Plant Extracts | 2012 |
[The relationship between the quality and the leaf shape of Magnolia officinalis produced in Hubei enshi].
Topics: Biphenyl Compounds; China; Chromatography, High Pressure Liquid; Lignans; Magnolia; Plant Bark; Plant Leaves; Plants, Medicinal; Quality Control | 2012 |
Maximizing dermal targeting and minimizing transdermal penetration by magnolol/honokiol methoxylation.
Topics: Adult; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cell Survival; Cells, Cultured; Female; Humans; In Vitro Techniques; Keratinocytes; Lignans; Mice; Mice, Nude; Neutrophils; Pancreatic Elastase; Skin; Skin Absorption; Skin Irritancy Tests; Superoxides; Swine; Young Adult | 2013 |
Screening active anti-breast cancer compounds from Cortex Magnolia officinalis by 2D LC-MS.
Topics: Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; Humans; Lignans; Magnolia; Mass Spectrometry | 2013 |
Neuroprotective effects of neolignans isolated from Magnoliae Cortex against glutamate-induced apoptotic stimuli in HT22 cells.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; BH3 Interacting Domain Death Agonist Protein; Biphenyl Compounds; Cell Death; Cell Line; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; JNK Mitogen-Activated Protein Kinases; Lignans; Magnoliaceae; Membrane Potential, Mitochondrial; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenyl Ethers; Phosphorylation; Picrates; Plant Extracts; Reactive Oxygen Species; Signal Transduction | 2013 |
[Study on the chemical constituents of Elephantopus mollis].
Topics: Asteraceae; Betulinic Acid; Biphenyl Compounds; Dibutyl Phthalate; Flavonoids; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Pentacyclic Triterpenes; Triterpenes | 2012 |
Honokiol dimers and magnolol derivatives with new carbon skeletons from the roots of Magnolia officinalis and their inhibitory effects on superoxide anion generation and elastase release.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Carbon; Dimerization; Ethanol; Humans; Inhibitory Concentration 50; Lignans; Magnolia; Neutrophils; Pancreatic Elastase; Plant Roots; Superoxides; Young Adult | 2013 |
Long-term supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in high-fat fed mice.
Topics: Adipogenesis; Adiponectin; Adipose Tissue, White; Adiposity; Animals; Biphenyl Compounds; Blood Glucose; Body Weight; Chemokine CCL2; Cholesterol; Diet, High-Fat; Dietary Supplements; Energy Metabolism; Glucose Tolerance Test; Inflammation; Insulin Resistance; Interleukin-10; Interleukin-6; Lignans; Liver; Male; Mice; Mice, Inbred C57BL; Triglycerides; Tumor Necrosis Factor-alpha | 2013 |
Chemopreventive effects of combination of honokiol and magnolol with α-santalol on skin cancer developments.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Biphenyl Compounds; Cell Proliferation; Drug Therapy, Combination; Female; Lignans; Mice; Neoplasms, Radiation-Induced; Polycyclic Sesquiterpenes; Sesquiterpenes; Skin Neoplasms; Ultraviolet Rays | 2013 |
[Simultaneous determination of six ingredients in Huoxiang Zhengqi oral liquid by UPLC].
Topics: Administration, Oral; Biphenyl Compounds; Chromatography, High Pressure Liquid; Disaccharides; Drugs, Chinese Herbal; Flavanones; Glucosides; Hesperidin; Lignans; Pharmaceutical Solutions | 2013 |
Magnolia dealbata seeds extract exert cytotoxic and chemopreventive effects on MDA-MB231 breast cancer cells.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; In Situ Nick-End Labeling; Inhibitory Concentration 50; Lignans; Magnolia; Mammary Neoplasms, Experimental; Mice, Nude; Seeds | 2014 |
Multiwalled-carbon-nanotubes-based matrix solid-phase dispersion extraction coupled with high-performance liquid chromatography for the determination of honokiol and magnolol in Magnoliae Cortex.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Lignans; Magnolia; Nanotubes, Carbon; Plant Extracts; Solid Phase Extraction | 2014 |
Assessment of the anti-diarrhea function of compound Chinese herbal medicine Cangpo Oral Liquid.
Topics: Animals; Antidiarrheals; Berberine; Biphenyl Compounds; Coptis; Diarrhea; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Intestines; Lignans; Magnolia; Male; Peristalsis; Phytotherapy; Swine | 2014 |
UPLC-MS/MS-ESI assay for simultaneous determination of magnolol and honokiol in rat plasma: application to pharmacokinetic study after administration emulsion of the isomer.
Topics: Administration, Intravenous; Administration, Oral; Animals; Biphenyl Compounds; Chromatography, Liquid; Emulsions; Lignans; Male; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway.
Topics: AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Cell Line; Diet, High-Fat; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Fatty Liver; Hepatocytes; Humans; Lignans; Lipogenesis; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Signal Transduction; Sterol Regulatory Element Binding Protein 1 | 2015 |
A new dimeric neolignan from Magnolia grandiflora L. seeds.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Drug Screening Assays, Antitumor; Humans; Lignans; Magnolia; Molecular Conformation; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Seeds | 2015 |
Polyethylene glycol-based ultrasound-assisted extraction of magnolol and honokiol from Cortex Magnoliae Officinalis.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lignans; Magnolia; Polyethylene Glycols; Ultrasonics | 2015 |
Construction of an immobilised acetylcholinesterase column and its application in screening insecticidal constituents from Magnolia officinalis.
Topics: Acetylcholinesterase; Alkaloids; Animals; Biphenyl Compounds; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Female; Hemiptera; Insecticides; Lignans; Magnolia; Plant Extracts; Sesquiterpenes | 2015 |
Structural analogues of the natural products magnolol and honokiol as potent allosteric potentiators of GABA(A) receptors.
Topics: Allosteric Regulation; Animals; Biological Products; Biphenyl Compounds; Lignans; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Isoforms; Receptors, GABA-A; Structure-Activity Relationship; Xenopus | 2014 |
Potential use of Magnolia officinalis bark polyphenols in the treatment of cannabis dependence.
Topics: Animals; Biphenyl Compounds; Cannabis; Humans; Inflammation; Lignans; Magnolia; Marijuana Abuse; Plant Bark; Plant Extracts; Polyphenols; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, G-Protein-Coupled | 2014 |
Metal-assisted synthesis of unsymmetrical magnolol and honokiol analogs and their biological assessment as GABAA receptor ligands.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; GABA Modulators; Lignans; Metals; Molecular Structure; Oocytes; Patch-Clamp Techniques; Protein Subunits; Rats; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus | 2015 |
The herbal-derived honokiol and magnolol enhances immune response to infection with methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA).
Topics: Animals; Anti-Bacterial Agents; Biphenyl Compounds; Caenorhabditis elegans; Cytokines; Humans; Lignans; Macrophages; Methicillin; Methicillin-Resistant Staphylococcus aureus; Mice; Plant Extracts; Plants, Medicinal; Staphylococcal Infections; Staphylococcus aureus | 2015 |
Effects of magnolol and honokiol on adhesion, yeast-hyphal transition, and formation of biofilm by Candida albicans.
Topics: Animals; Antifungal Agents; Biofilms; Biphenyl Compounds; Caenorhabditis elegans; Candida albicans; Cell Adhesion; Cell Line; Drugs, Chinese Herbal; Fungal Proteins; Hyphae; Lignans; Microscopy, Confocal; Models, Animal; Rats; Signal Transduction; Titanium; Virulence | 2015 |
Magnolol and honokiol regulate the calcium-activated potassium channels signaling pathway in Enterotoxigenic Escherichia coli-induced diarrhea mice.
Topics: Animals; Biphenyl Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Chlorides; Diarrhea; Enterotoxigenic Escherichia coli; Escherichia coli Infections; Ileum; Inositol 1,4,5-Trisphosphate Receptors; Lignans; Male; Mice; Potassium; Potassium Channels, Calcium-Activated; Protein Kinase C; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Sodium | 2015 |
New mechanism of magnolol and honokiol from Magnolia officinalis against Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Biphenyl Compounds; Humans; Lignans; Magnolia; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Plant Exudates; Staphylococcal Infections; Staphylococcus aureus | 2014 |
A novel 9 × 9 map-based solvent selection strategy for targeted counter-current chromatography isolation of natural products.
Topics: Abietanes; Biological Products; Biphenyl Compounds; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Countercurrent Distribution; Hexanes; Lignans; Magnolia; Methanol; Reproducibility of Results; Salvia miltiorrhiza; Solvents; Water | 2015 |
Comparative pharmacokinetics and brain distribution of magnolol and honokiol after oral administration of Magnolia officinalis cortex extract and its compatibility with other herbal medicines in Zhi-Zi-Hou-Po Decoction to rats.
Topics: Administration, Oral; Animals; Biphenyl Compounds; Brain Chemistry; Chromatography, High Pressure Liquid; Drug Interactions; Drugs, Chinese Herbal; Iridoids; Lignans; Magnolia; Male; Plant Extracts; Rats; Tissue Distribution | 2016 |
Simultaneous determination of ten compounds in rat plasma by UPLC-MS/MS: Application in the pharmacokinetic study of Ma-Zi-Ren-Wan.
Topics: Animals; Anthraquinones; Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Glycosides; Lignans; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2015 |
Inhibitory effects of magnolol and honokiol on human calcitonin aggregation.
Topics: Biphenyl Compounds; Calcitonin; Calorimetry; Cell Line, Tumor; Dynamic Light Scattering; Humans; Lignans; Magnolia; Medicine, Chinese Traditional; Microscopy, Electron, Transmission; Polyphenols; Protein Binding | 2015 |
Antimicrobial Effects and Resistant Regulation of Magnolol and Honokiol on Methicillin-Resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Biphenyl Compounds; Hexanes; Lignans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxacillin; Plant Extracts | 2015 |
Antioxidant Activity of Magnolol and Honokiol: Kinetic and Mechanistic Investigations of Their Reaction with Peroxyl Radicals.
Topics: Acetonitriles; Anisoles; Antioxidants; Biphenyl Compounds; Hydrogen Bonding; Kinetics; Lignans; Molecular Structure; Oxidation-Reduction; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Superoxides | 2015 |
Anti-biofilm and bactericidal effects of magnolia bark-derived magnolol and honokiol on Streptococcus mutans.
Topics: Anti-Bacterial Agents; Biofilms; Biphenyl Compounds; Cell Line; Dose-Response Relationship, Drug; Gingiva; Humans; Lignans; Magnolia; Microbial Sensitivity Tests; Microscopy, Fluorescence; Plant Bark; Plant Extracts; Streptococcus mutans | 2016 |
[Transglycosylation of neolignans by enzymatic synthesis and evaluation of their antitumor activity].
Topics: Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Cell Line, Tumor; Chromatography, High Pressure Liquid; Glucosides; Glycosylation; Humans; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry | 2015 |
In vitro synergism of magnolol and honokiol in combination with antibacterial agents against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
Topics: Anti-Bacterial Agents; Biphenyl Compounds; Drug Synergism; Lignans; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests | 2015 |
New in vitro insights on a cell death pathway induced by magnolol and honokiol in aristolochic acid tubulotoxicity.
Topics: Aristolochic Acids; Biphenyl Compounds; Cell Cycle; Cell Line; Free Radical Scavengers; Humans; Kidney Tubules; Lignans; Molecular Structure; Oxidative Stress; Picrates | 2016 |
[Quality Suitability of Magnolia officinalis in China Based on GIS].
Topics: Biphenyl Compounds; China; Geographic Information Systems; Lignans; Magnolia | 2015 |
Quality evaluation of the leaves of Magnolia officinalis var. biloba using high-performance liquid chromatography fingerprint analysis of phenolic compounds.
Topics: Biphenyl Compounds; China; Chromatography; Chromatography, High Pressure Liquid; Glucosides; Lignans; Magnolia; Mannosides; Phenols; Plant Extracts; Plant Leaves; Proanthocyanidins; Quercetin; Reference Values; Reproducibility of Results; Rutin; Temperature | 2016 |
Magnolol and honokiol exert a synergistic anti-tumor effect through autophagy and apoptosis in human glioblastomas.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Biphenyl Compounds; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Glioblastoma; Humans; Lignans; Mice; Mice, Nude; Xenograft Model Antitumor Assays | 2016 |
Effect of Chemical Profiling Change of Processed Magnolia officinalis on the Pharmacokinetic Profiling of Honokiol and Magnolol in Rats.
Topics: Alkaloids; Animals; Biphenyl Compounds; Chromatography, Liquid; Cluster Analysis; Drugs, Chinese Herbal; Humans; Lignans; Magnolia; Male; Multivariate Analysis; Plant Stems; Principal Component Analysis; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Magnolol and honokiol from Magnolia officinalis enhanced antiviral immune responses against grass carp reovirus in Ctenopharyngodon idella kidney cells.
Topics: Animals; Biphenyl Compounds; Carps; Cell Line; Colorimetry; Cytopathogenic Effect, Viral; Fish Diseases; Immunity, Innate; Lignans; Magnolia; Reoviridae; Reoviridae Infections; Tetrazolium Salts; Thiazoles | 2017 |
[Pharmacokinetics of magnolol and honokiol in Weichang'an pill].
Topics: Animals; Biphenyl Compounds; Drugs, Chinese Herbal; Lignans | 2016 |
Synthesis of magnolol and honokiol derivatives and their effect against hepatocarcinoma cells.
Topics: Biphenyl Compounds; Carbon-13 Magnetic Resonance Spectroscopy; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Lignans; Liver Neoplasms; Proton Magnetic Resonance Spectroscopy | 2018 |
Simultaneous determination of Magnolol and Honokiol by amino acid ionic liquid synchronous fluorescence spectrometry.
Topics: Amino Acids; Biphenyl Compounds; Hydrogen-Ion Concentration; Imidazoles; Ionic Liquids; Lignans; Limit of Detection; Linear Models; Models, Molecular; Reproducibility of Results; Spectrometry, Fluorescence; Temperature | 2018 |
Magnolol and Honokiol Attenuate Apoptosis of Enterotoxigenic Escherichia Coli-Induced Intestinal Epithelium by Maintaining Secretion and Absorption Homeostasis and Protecting Mucosal Integrity.
Topics: Administration, Oral; Animals; Apoptosis; Biphenyl Compounds; Cytokines; Enterotoxigenic Escherichia coli; Homeostasis; Inflammation Mediators; Intestinal Absorption; Intestinal Mucosa; Lignans; Mice; Nitric Oxide Synthase | 2018 |
Modulation of Rat Hepatic CYP1A and 2C Activity by Honokiol and Magnolol: Differential Effects on Phenacetin and Diclofenac Pharmacokinetics In Vivo.
Topics: Administration, Intravenous; Animals; Biphenyl Compounds; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Gene Expression Regulation; Lignans; Liver; Microsomes, Liver; Molecular Structure; Phenacetin; Rats; Rats, Sprague-Dawley | 2018 |
Honokiol and Magnolol Inhibit CXCL10 and CXCL11 Production in IL-27-Stimulated Human Oral Epithelial Cells.
Topics: Anti-Inflammatory Agents; Biphenyl Compounds; Chemokine CXCL10; Chemokine CXCL11; Epithelial Cells; Humans; Interleukin-27; Ligands; Lignans; Mouth; Periodontal Diseases; Proto-Oncogene Proteins c-akt; Receptors, CXCR3; STAT3 Transcription Factor | 2018 |
Bioinspired Honokiol Analogs and Their Evaluation for Activity on the Norepinephrine Transporter.
Topics: Adrenergic Neurons; Anti-Anxiety Agents; Benzhydryl Compounds; Biphenyl Compounds; Central Nervous System; HEK293 Cells; Humans; Lignans; Magnolia; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Plant Bark; Plant Extracts; Receptors, GABA-A | 2018 |
In vitro metabolism of magnolol and honokiol in rat liver microsomes and their interactions with seven cytochrome P substrates.
Topics: Animals; Biphenyl Compounds; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Inactivation, Metabolic; Inhibitory Concentration 50; Lignans; Male; Mass Spectrometry; Microsomes, Liver; Rats, Sprague-Dawley; Substrate Specificity | 2019 |
How changes in column geometry and packing ratio can increase sample load and throughput by a factor of fifty in Counter-Current Chromatography.
Topics: Biphenyl Compounds; Chemistry, Pharmaceutical; Countercurrent Distribution; Hexanes; Lignans; Methanol; Solvents; Water | 2018 |
Identification of minor lignans, alkaloids, and phenylpropanoid glycosides in Magnolia officinalis by HPLC‒DAD‒QTOF-MS/MS.
Topics: Alkaloids; Aporphines; Biphenyl Compounds; Chromatography, High Pressure Liquid; Glucosides; Glycosides; Isoquinolines; Lignans; Magnolia; Methanol; Phenols; Propanols; Tandem Mass Spectrometry | 2019 |
Antifungal Effect of Magnolol and Honokiol from
Topics: Alternaria; Antifungal Agents; Biphenyl Compounds; Lignans; Magnolia; Nicotiana; Plant Diseases | 2019 |
Honokiol, magnolol and its monoacetyl derivative show strong anti-fungal effect on Fusarium isolates of clinical relevance.
Topics: Antifungal Agents; Biphenyl Compounds; Fusariosis; Fusarium; Humans; Lignans; Microbial Sensitivity Tests; Plant Diseases | 2019 |
Magnolol protects PC12 cells from hydrogen peroxide or 6-hydroxydopamine induced cytotoxicity.
Topics: Animals; Biphenyl Compounds; Catalase; Cell Death; Cell Survival; Hydrogen Peroxide; Lignans; NAD(P)H Dehydrogenase (Quinone); Oxidopamine; PC12 Cells; Protective Agents; Rats | 2019 |
Zebrafish-Based Screening of Antiseizure Plants Used in Traditional Chinese Medicine:
Topics: Animals; Anticonvulsants; Biphenyl Compounds; Epilepsy; Lignans; Magnolia; Medicine, Chinese Traditional; Mice; Plant Extracts; Zebrafish | 2020 |
Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Cell Line, Tumor; Drug Evaluation, Preclinical; Female; Humans; Lignans; Magnolia; Mice; Mice, Nude; Mitochondria; Mouth Neoplasms; Plant Extracts; Reactive Oxygen Species | 2020 |
Network Pharmacology and Bioactive Equivalence Assessment Integrated Strategy Driven Q-markers Discovery for Da-Cheng-Qi Decoction to Attenuate Intestinal Obstruction.
Topics: Algorithms; Animals; Anthraquinones; Biomarkers, Pharmacological; Biphenyl Compounds; Data Mining; Drugs, Chinese Herbal; Flavanones; HT29 Cells; Humans; Intestinal Obstruction; Lignans; Male; Phosphatidylinositol 3-Kinases; Rats, Sprague-Dawley; Reproducibility of Results; Therapeutic Equivalency | 2020 |
Thin-layer chromatographic quantification of magnolol and honokiol in dietary supplements and selected biological properties of these preparations.
Topics: Biphenyl Compounds; Chromatography, Thin Layer; Densitometry; Dietary Supplements; Lignans; Limit of Detection; Magnolia; Medicine, East Asian Traditional; Plant Bark | 2020 |
Preparation of restricted access monolithic tip via unidirectional freezing and atom transfer radical polymerization for directly extracting magnolol and honokiol from rat plasma followed by liquid chromatography analysis.
Topics: Animals; Biphenyl Compounds; Chromatography, High Pressure Liquid; Freezing; Hydrophobic and Hydrophilic Interactions; Lignans; Methacrylates; Polyethylene Glycols; Quality Control; Rats; Reproducibility of Results; Solid Phase Extraction | 2020 |
In vitro antimicrobial and antipro-inflammation potential of honokiol and magnolol against oral pathogens and macrophages.
Topics: Animals; Anti-Bacterial Agents; Biphenyl Compounds; Humans; Inflammation; Lignans; Macrophages | 2021 |
A Simple and Sensitive Dispersive Micro-Solid-Phase Extraction Coupled with High-Performance Liquid Chromatography for Quantification of Honokiol and Magnolol in Complex Matrices.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Lignans; Magnolia; Solid Phase Extraction | 2020 |
Synthesis, Characterization and Biological Evaluation of Magnolol and Honokiol Derivatives with 1,3,5-Triazine of Metformin Cyclization.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic; Cyclization; Cytokines; Gene Expression Regulation; Humans; Lignans; Macrophages; Metformin; Mice; Molecular Structure; RAW 264.7 Cells; Structure-Activity Relationship; Triazines | 2020 |
Surface plasmon resonance biosensor combined with lentiviral particle stabilization strategy for rapid and specific screening of P-Glycoprotein ligands.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Products; Biosensing Techniques; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Cyclosporine; Cyclosporins; Dogs; Drug Evaluation, Preclinical; HEK293 Cells; Humans; In Vitro Techniques; Kinetics; Lentivirus; Ligands; Lignans; Madin Darby Canine Kidney Cells; MCF-7 Cells; Membrane Proteins; Resveratrol; Surface Plasmon Resonance | 2021 |
Application of hollow fiber centrifugal ultrafiltrate purification as the pretreatment technology for traditional Chinese medicine: its application for analysis of honokiol and magnolol in TCM preparations containing Cortex Magnoliae Officinalis.
Topics: Biphenyl Compounds; Humans; Lignans; Medicine, Chinese Traditional; Reproducibility of Results; Technology | 2021 |
Magnolol and Honokiol Inhibited the Function and Expression of BCRP with Mechanism Exploration.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biphenyl Compounds; Cell Survival; Dogs; Drug Resistance, Multiple; Drug Resistance, Neoplasm; ErbB Receptors; Lignans; Madin Darby Canine Kidney Cells; Magnolia; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Extracts; Polyphenols; Signal Transduction | 2021 |
Magnolol and honokiol target TRPC4 to regulate extracellular calcium influx and relax intestinal smooth muscle.
Topics: Animals; Biphenyl Compounds; Calcium Signaling; HEK293 Cells; Humans; Intestines; Lignans; Male; Medicine, Chinese Traditional; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; TRPC Cation Channels; TRPV Cation Channels | 2022 |
Pharmacokinetics and metabolites of glycosides and lignans of the stem bark of Magnolia officinalis in functional dyspepsia and normal rats using liquid chromatography-tandem mass spectrometry.
Topics: Animals; Biphenyl Compounds; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dyspepsia; Glycosides; Lignans; Magnolia; Plant Bark; Rats; Tandem Mass Spectrometry | 2022 |
Magnolia officinalis L. bark extract and respiratory diseases: From traditional Chinese medicine to western medicine via network target.
Topics: Biphenyl Compounds; Humans; Lignans; Magnolia; Medicine, Chinese Traditional; Plant Bark; Plant Extracts; Respiratory Tract Diseases | 2023 |
Evaluation of honokiol, magnolol and of a library of new nitrogenated neolignans as pancreatic lipase inhibitors.
Topics: Biphenyl Compounds; Lignans | 2023 |
[Processing Magnoliae Officinalis Cortex with ginger juice: process optimization based on AHP-CRITIC weighting method and composition changes after processing].
Topics: Biphenyl Compounds; Drugs, Chinese Herbal; Lignans; Magnolia; Zingiber officinale | 2023 |
Affinity character analysis of magnolol and honokiol based on stepwise frontal analysis coupled with cell membrane chromatography.
Topics: Biphenyl Compounds; Cell Membrane; Chromatography; Lignans; Vascular Endothelial Growth Factor A | 2023 |