magnolin has been researched along with lignans in 26 studies
| Studies (magnolin) | Trials (magnolin) | Recent Studies (post-2010) (magnolin) | Studies (lignans) | Trials (lignans) | Recent Studies (post-2010) (lignans) |
|---|---|---|---|---|---|
| 27 | 0 | 19 | 7,024 | 95 | 4,172 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 16 (61.54) | 24.3611 |
| 2020's | 4 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Han, G; Ma, Y | 1 |
| Bataille, CJ; Brown, RC; Bruton, G; Hinks, JD; Swain, NA | 1 |
| Huang, Y; Liu, J; Ni, M; Sun, S | 1 |
| Baek, JA; Go, HK; Kim, AM; Kim, JP; Lee, CB; Lee, YD; Na, DJ; Rhee, YK; Seo, JJ | 1 |
| Jeon, R; Kim, DH; Kim, HD; Kim, JS; Kim, JY; Lee, da Y; Lee, HJ; Lim, HJ; Ryu, JH | 1 |
| Kim, NJ; Lee, HK; Lee, HS; Oh, SR | 1 |
| Kim, NJ; Lee, HK; Lee, HS; Oh, SR; Song, WY; Yoo, SD | 1 |
| Jeong, JH; Ji, HY; Kim, DK; Lee, HK; Lee, HS; Oh, SR | 1 |
| Jeong, JH; Ji, HY; Kim, DK; Lee, HK; Lee, HS; Liu, KH; Oh, SR | 1 |
| Chung, WY; Jun, AY; Kim, HJ; Lee, DH; Park, KK; Son, KH; Woo, MH | 1 |
| Cho, YY; Dong, Z; Lee, CJ; Lee, HK; Lee, HS; Lee, JY; Lee, MH; Li, Y; Oh, SR; Ryu, HW | 1 |
| Deng, YH; Liu, YQ; Peng, CY; Wang, YH; Zhou, XJ | 1 |
| Gui, D; Li, J; Wang, F; Wang, N; Xing, T; Zhang, G; Zhou, Y | 1 |
| Cho, YY; Choi, KI; Jang, JH; Lee, CJ; Lee, HS; Lee, MH; Oh, SR; Ryu, HW; Song, JH; Surh, YJ; Yoo, SM | 1 |
| Chen, M; Huang, Y; Wang, F; Xiao, J; Zhang, G; Zhang, X; Zhu, W; Zou, X | 1 |
| Jeong, HU; Kim, JH; Kwon, SS; Lee, HS | 1 |
| Gao, X; Han, L; Jin, C; Pang, X; Qiu, Y; Shao, Y; Sun, J; Wang, T; Yin, S; Yu, H; Zhang, Y; Zhou, S | 1 |
| An, HJ; Cho, YY; Kang, HC; Kim, DJ; Kim, KD; Lee, CJ; Lee, HS; Lee, JY; Song, JH; Yoo, SM | 1 |
| Cha, BY; Efferth, T; Kadioglu, O; Mitani, Y; Nakagawa, H; Nakamura, I; Satake, K; Teruya, T; Tsukamoto, M; Woo, JT; Yonezawa, T | 1 |
| An, HJ; Cho, YY; Kang, HC; Kim, DJ; Kim, KD; Lee, CJ; Lee, HS; Lee, JY; Yoo, SM | 1 |
| Bak, Y; Chun, HW; Hong, JT; Kim, SJ; Oh, J; Oh, SR; Pham, TH; Ryu, HW; Yoon, DY | 1 |
| An, H; Che, D; He, H; Li, C; Ma, P; Zhang, T; Zhang, Y; Zhao, T | 1 |
| Huang, K; Shi, L; Wang, J; Zhang, Q; Zhang, S | 1 |
| Ohta, T; Shoyama, Y; Tung, NH; Uto, T | 1 |
| Abdelmohsen, UR; El-Hawary, SS; Ghareeb, MA; Sayed, AM | 1 |
| Bhuia, MS; Chowdhury, R; Coutinho, HDM; Islam, MT; Kamli, H; Rakib, AI; Shaikh, A; Wilairatana, P | 1 |
1 review(s) available for magnolin and lignans
| Article | Year |
|---|---|
Anticancer Potentials of the Lignan Magnolin: A Systematic Review.
Topics: Cell Cycle; Humans; Lignans; Neoplasms; Phytochemicals; Signal Transduction | 2023 |
25 other study(ies) available for magnolin and lignans
| Article | Year |
|---|---|
[Biologically active lignins from Magnolia biondii Pamp].
Topics: Drugs, Chinese Herbal; Lignans; Lignin; Molecular Conformation | 1995 |
C-H insertion approach to the synthesis of endo,exo-furofuranones: synthesis of (+/-)-asarinin, (+/-)-epimagnolin A, and (+/-)-fargesin.
Topics: Anti-Allergic Agents; Anticholesteremic Agents; Antihypertensive Agents; Antineoplastic Agents; Antioxidants; Dioxoles; Drugs, Chinese Herbal; Furans; Lignans; Lignin; Platelet Aggregation Inhibitors | 2001 |
[Study on percutaneous absorption of Xuetie Dingchuan Plaster].
Topics: Administration, Cutaneous; Animals; Azepines; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Drugs, Chinese Herbal; Ethanol; Female; In Vitro Techniques; Lignans; Lignin; Liposomes; Male; Mice; Skin Absorption | 2005 |
Extracts of Magnoliae flos inhibit inducible nitric oxide synthase via ERK in human respiratory epithelial cells.
Topics: Analysis of Variance; Animals; Benzodioxoles; Cell Line; Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression; Humans; Interferon-gamma; Interleukin-1beta; Lignans; Magnolia; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Respiratory Mucosa; RNA, Messenger; Seeds; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2009 |
In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Humans; I-kappa B Proteins; Lignans; Lignin; Magnetic Resonance Spectroscopy; Magnolia; Neurons; NF-KappaB Inhibitor alpha; Nitric Oxide; Plant Extracts; Transcription Factor RelA | 2009 |
Simultaneous determination of magnolin and epimagnolin A in rat plasma by liquid chromatography with tandem mass spectrometry: Application to pharmacokinetic study of a purified extract of the dried flower buds of Magnolia fargesii, NDC-052 in rats.
Topics: Animals; Calibration; Chromatography, Liquid; Drugs, Chinese Herbal; Lignans; Magnolia; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Pharmacokinetics of magnolin in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Biotransformation; Carrier Proteins; Chromatography, High Pressure Liquid; Half-Life; Histamine Antagonists; Injections, Intravenous; Intestinal Absorption; Lignans; Male; Metabolic Clearance Rate; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
Liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry for the simultaneous determination of dimethoxyaschantin, dimethylliroresinol, dimethylpinoresinol, epimagnolin A, fargesin and magnolin in rat plasma.
Topics: Animals; Benzodioxoles; Chromatography, Liquid; Drug Stability; Flowers; Furans; Lignans; Linear Models; Magnolia; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2011 |
In vitro metabolism of magnolin and characterization of cytochrome P450 enzymes responsible for its metabolism in human liver microsomes.
Topics: Biotransformation; Computer Simulation; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Kinetics; Lignans; Mass Spectrometry; Metabolic Networks and Pathways; Microsomes, Liver; NADP; Recombinant Proteins | 2011 |
Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts.
Topics: Animals; Benzodioxoles; Bone Resorption; Breast Neoplasms; Cell Line, Tumor; Female; Furans; Gene Expression Regulation, Neoplastic; Humans; Lignans; Lignin; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Osteoblasts; Osteoclasts; Osteoprotegerin; Parathyroid Hormone-Related Protein; RANK Ligand; RNA, Messenger | 2014 |
Targeting of magnolin on ERKs inhibits Ras/ERKs/RSK2-signaling-mediated neoplastic cell transformation.
Topics: Animals; Blotting, Western; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Drugs, Chinese Herbal; Embryo, Mammalian; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Lignans; Mice; Mice, Knockout; NIH 3T3 Cells; ras Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction | 2014 |
Lignans from the bark of Zanthoxylum simulans.
Topics: Drugs, Chinese Herbal; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Zanthoxylum | 2015 |
Magnolin protects against contrast-induced nephropathy in rats via antioxidation and antiapoptosis.
Topics: Animals; Apoptosis; Contrast Media; Kidney Diseases; Lignans; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Triiodobenzoic Acids | 2014 |
Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling pathway.
Topics: Animals; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Humans; Lignans; Mice; NF-kappa B; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Transcriptional Activation | 2015 |
Magnolin inhibits prostate cancer cell growth in vitro and in vivo.
Topics: Animals; Apoptosis; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Humans; Lignans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Suppressor Protein p53 | 2017 |
Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes.
Topics: Benzodioxoles; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Furans; Humans; Lignans; Microsomes, Liver | 2017 |
Magnolin promotes autophagy and cell cycle arrest via blocking LIF/Stat3/Mcl-1 axis in human colorectal cancers.
Topics: Animals; Autophagy; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Leukemia Inhibitory Factor; Lignans; Mice, Inbred BALB C; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Prognosis; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2018 |
Magnolin targeting of ERK1/2 inhibits cell proliferation and colony growth by induction of cellular senescence in ovarian cancer cells.
Topics: Animals; Apoptosis; Cell Proliferation; Cellular Senescence; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lignans; Male; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovarian Neoplasms; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Epimagnolin A, a tetrahydrofurofuranoid lignan from Magnolia fargesii, reverses ABCB1-mediated drug resistance.
Topics: Adenosine Triphosphatases; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lignans; Magnolia; Molecular Docking Simulation; Verapamil | 2018 |
Epimagnolin targeting on an active pocket of mammalian target of rapamycin suppressed cell transformation and colony growth of lung cancer cells.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Drugs, Chinese Herbal; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; G1 Phase Cell Cycle Checkpoints; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Lignans; Lung Neoplasms; Mice; Molecular Docking Simulation; Phosphorylation; Protein Conformation; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; RNA, Small Interfering; TOR Serine-Threonine Kinases | 2019 |
Epimagnolin A inhibits IL-6 production by inhibiting p38/NF-κB and AP-1 signaling pathways in PMA-stimulated THP-1 cells.
Topics: Anti-Inflammatory Agents; Benzodioxoles; Down-Regulation; Humans; Interleukin-6; Lignans; Macrophage Activation; MAP Kinase Signaling System; Monocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Signal Transduction; THP-1 Cells; Transcription Factor AP-1 | 2019 |
Magnolin inhibits IgE/Ag-induced allergy in vivo and in vitro.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Antigens; Calcium; Cell Line; Cell Survival; Cytokines; Edema; Histamine; Humans; Hypersensitivity; Immunoglobulin E; Lignans; Male; Mast Cells; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Peptide Hydrolases | 2019 |
Magnolin Inhibits Proliferation and Invasion of Breast Cancer MDA-MB-231 Cells by Targeting the ERK1/2 Signaling Pathway.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lignans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Structure-Activity Relationship; Wound Healing | 2020 |
(+)-Magnolin Enhances Melanogenesis in Melanoma Cells and Three-Dimensional Human Skin Equivalent; Involvement of PKA and p38 MAPK Signaling Pathways.
Topics: Animals; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Humans; Lignans; Melanins; Melanoma; Melanoma, Experimental; Methanol; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; p38 Mitogen-Activated Protein Kinases; Signal Transduction | 2022 |
Antiproliferative potential of
Topics: Cell Line, Tumor; Cell Proliferation; Humans; Lignans; Matrix Metalloproteinase 3; Pancreatic Neoplasms; Physalis | 2022 |