Page last updated: 2024-08-25

madecassic acid and madecassoside

madecassic acid has been researched along with madecassoside in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's10 (83.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H1
Bonfill, M; Cusidó, RM; Mangas, S; Osuna, L; Palazón, J; Piñol, MT1
Jo, BG; Jung, HJ; Koh, DJ; Lee, JY; Lee, KT; Park, HJ; Shin, JS; Won, JH; Yun, K1
Panichayupakaranant, P; Puttarak, P1
Dubery, IA; James, JT; Steenkamp, PA; Tugizimana, F1
Shen, Q; Yu, LS; Zeng, S; Zhou, H1
Dai, Y; Gao, FF; Jiang, CJ; Leng, DD; Wang, T; Xia, YF1
Dai, Y; Dou, Y; Kong, L; Leng, D; Wang, T; Wei, Z; Xia, Y; Yang, Y1
Dai, Y; Lv, Q; Qiao, SM; Wei, ZF; Xia, Y; Xia, YF; Yang, Y; Yue, MF1
Dai, Y; Tong, B; Wang, Y; Wei, W; Wei, Z; Xia, Y; Xu, X; Zhao, P1
Agarwal, A; Arora, R; Gupta, YK; Kumar, R; Reeta, KH1
Fong, LY; Ng, CT; Razali, NNM1

Reviews

1 review(s) available for madecassic acid and madecassoside

ArticleYear
Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review.
    Planta medica, 2019, Volume: 85, Issue:16

    Topics: Cardiovascular Diseases; Centella; Humans; Pentacyclic Triterpenes; Plant Extracts; Plants, Medicinal; Triterpenes

2019

Other Studies

11 other study(ies) available for madecassic acid and madecassoside

ArticleYear
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha

2021
Identification of triterpenoid compounds of Centella asiatica by thin-layer chromatography and mass spectrometry.
    Biomedical chromatography : BMC, 2006, Volume: 20, Issue:2

    Topics: Centella; Chromatography, Thin Layer; Mass Spectrometry; Pentacyclic Triterpenes; Terpenes; Triterpenes

2006
Anti-inflammatory effects of madecassic acid via the suppression of NF-kappaB pathway in LPS-induced RAW 264.7 macrophage cells.
    Planta medica, 2010, Volume: 76, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Centella; Cyclooxygenase 2; Down-Regulation; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Plant Extracts; RNA, Messenger; Triterpenes; Tumor Necrosis Factor-alpha

2010
Factors affecting the content of pentacyclic triterpenes in Centella asiatica raw materials.
    Pharmaceutical biology, 2012, Volume: 50, Issue:12

    Topics: Agriculture; Centella; Chromatography, High Pressure Liquid; Ethanol; Flowers; Fruit; Microwaves; Pentacyclic Triterpenes; Plant Extracts; Plant Leaves; Plant Roots; Plants, Medicinal; Powders; Seasons; Solvents; Thailand; Triterpenes

2012
Metabolomic analysis of methyl jasmonate-induced triterpenoid production in the medicinal herb Centella asiatica (L.) urban.
    Molecules (Basel, Switzerland), 2013, Apr-11, Volume: 18, Issue:4

    Topics: Acetates; Centella; Chromatography, High Pressure Liquid; Cyclopentanes; Gas Chromatography-Mass Spectrometry; Metabolomics; Oxylipins; Pentacyclic Triterpenes; Plant Extracts; Plants, Medicinal; Triterpenes

2013
[Simultaneous determination of madecassoside, asiaticoside and their aglycones in Centella asiatica (L.) urban extracts by RP-HPLC].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2014, Volume: 43, Issue:2

    Topics: Centella; Chromatography, High Pressure Liquid; Pentacyclic Triterpenes; Plant Extracts; Reproducibility of Results; Triterpenes

2014
A LC-ESI-MS method for the simultaneous determination of madecassoside and its metabolite madecassic acid in rat plasma: comparison pharmacokinetics in normal and collagen-induced arthritic rats.
    Chinese journal of natural medicines, 2014, Volume: 12, Issue:12

    Topics: Animals; Antirheumatic Agents; Area Under Curve; Arthritis, Experimental; Arthritis, Rheumatoid; Centella; Chromatography, Liquid; Collagen; Female; Phytotherapy; Plant Extracts; Rats, Wistar; Reference Values; Severity of Illness Index; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triterpenes

2014
Intestinal interleukin-10 mobilization as a contributor to the anti-arthritis effect of orally administered madecassoside: a unique action mode of saponin compounds with poor bioavailability.
    Biochemical pharmacology, 2015, Mar-01, Volume: 94, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Centella; Female; Injections, Intraperitoneal; Interleukin-10; Intestinal Absorption; Intestinal Mucosa; Intestines; Plant Extracts; Rats; Rats, Wistar; Saponins; Triterpenes

2015
Madecassoside ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting the generation of hepatocyte growth factor via PPAR-γ in colon.
    British journal of pharmacology, 2016, Volume: 173, Issue:7

    Topics: Animals; Bleomycin; Cell Line, Tumor; Cell Survival; Colon; Female; Gene Silencing; Hepatocyte Growth Factor; Intestinal Mucosa; Lung; Mice, Inbred ICR; PPAR gamma; Pulmonary Fibrosis; Triterpenes

2016
Madecassic acid, the contributor to the anti-colitis effect of madecassoside, enhances the shift of Th17 toward Treg cells via the PPARγ/AMPK/ACC1 pathway.
    Cell death & disease, 2017, 03-30, Volume: 8, Issue:3

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Colitis; Cytokines; Female; Mice; PPAR gamma; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells; Triterpenes

2017
Comparison of three different extracts of Centella asiatica for anti-amnesic, antioxidant and anticholinergic activities: in vitro and in vivo study.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 105

    Topics: Amnesia; Animals; Antioxidants; Centella; Cholinergic Antagonists; Cholinesterase Inhibitors; Cholinesterases; Male; Memory Disorders; Methanol; Oxidants; Oxidative Stress; Pentacyclic Triterpenes; Plant Extracts; Rats; Rats, Wistar; Scopolamine; Triterpenes

2018