Page last updated: 2024-08-25

madecassic acid and asiatic acid

madecassic acid has been researched along with asiatic acid in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (17.39)18.2507
2000's7 (30.43)29.6817
2010's10 (43.48)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Choi, H; Jew, SS; Jung, MW; Jung, YH; Kim, H; Lim, DY; Mook-Jung, I; Park, HG; Yoo, CH1
Alexacou, KM; Cheng, K; Gimisis, T; Hao, J; Hayes, JM; Leonidas, DD; Liu, J; Ni, P; Oikonomakos, NG; Sun, H; Wen, X; Zhang, L; Zhang, P; Zographos, SE1
Hong, D; Hu, LH; Li, J; Li, JY; Shen, Q; Shi, L; Zhang, W; Zhang, YN1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Feng, Y; Mei, Z; Wang, C; Yang, G; Yang, J; Yang, X; Zhao, P; Zhou, Q1
Buckle, R; Eldridge, GR; Ellis, M; Garo, E; Hu, JF; Huang, Z; Lawrence, JA; Norman, VL; Rathinavelu, S; Starks, CM; Williams, RB1
Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H1
Bellon, G; Borel, JP; Gillery, P; Maquart, FX; Wegrowski, Y1
Bonte, F; Chaudagne, C; Dumas, M; Meybeck, A1
Hausen, BM1
Birembaut, P; Chastang, F; Gillery, P; Maquart, FX; Simeon, A; Wegrowski, Y1
Ali, JM; Coldren, CD; Hashim, P; Oh, SK; Rha, C; Sinskey, AJ1
Bonfill, M; Cusidó, RM; Mangas, S; Osuna, L; Palazón, J; Piñol, MT1
Blankschtein, D; Goldsipe, A; Stephenson, BC1
Coradetti, ST; Fong, KW; Goldsipe, A; Rafat, M; Rha, C; Sambandan, TG; Sinskey, AJ; Stephenson, BC1
Abd-Rashid, BA; Er, HM; Ismail, R; Ismail, Z; Mak, JW; Ong, CE; Pan, Y; Pook, PC1
Panichayupakaranant, P; Puttarak, P1
Dubery, IA; James, JT; Steenkamp, PA; Tugizimana, F1
Brzezińska, M; Bylka, W; Dańczak-Pazdrowska, A; Studzińska-Sroka, E; Znajdek-Awiżeń, P1
Shen, Q; Yu, LS; Zeng, S; Zhou, H1
Bai, L; Li, X; Xia, B; Xiong, J; Xu, P; Xue, M1
Agarwal, A; Arora, R; Gupta, YK; Kumar, R; Reeta, KH1
Fong, LY; Ng, CT; Razali, NNM1

Reviews

2 review(s) available for madecassic acid and asiatic acid

ArticleYear
Centella asiatica in dermatology: an overview.
    Phytotherapy research : PTR, 2014, Volume: 28, Issue:8

    Topics: Animals; Centella; Dermatology; Humans; Pentacyclic Triterpenes; Plant Extracts; Plants, Medicinal; Skin Diseases; Triterpenes; Wound Healing

2014
Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review.
    Planta medica, 2019, Volume: 85, Issue:16

    Topics: Cardiovascular Diseases; Centella; Humans; Pentacyclic Triterpenes; Plant Extracts; Plants, Medicinal; Triterpenes

2019

Other Studies

21 other study(ies) available for madecassic acid and asiatic acid

ArticleYear
Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.
    Bioorganic & medicinal chemistry letters, 2000, Jan-17, Volume: 10, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Death; Cell Line; Humans; Molecular Structure; Neuroprotective Agents; Pentacyclic Triterpenes; Peptide Fragments; Plants, Medicinal; Structure-Activity Relationship; Triterpenes

2000
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Adenosine Monophosphate; Allosteric Site; Animals; Binding Sites; Crystallography, X-Ray; Glycogen Phosphorylase; Hypoglycemic Agents; Kinetics; Models, Molecular; Muscles; Oleanolic Acid; Pentacyclic Triterpenes; Protein Binding; Protein Conformation; Rabbits; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2008
Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Insulin; Obesity; Oleanolic Acid; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Insulin; Structure-Activity Relationship; T-Lymphocytes

2008
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Chemical constituents from Eucalyptus citriodora Hook leaves and their glucose transporter 4 translocation activities.
    Bioorganic & medicinal chemistry letters, 2014, Jul-15, Volume: 24, Issue:14

    Topics: Animals; Cell Line; Chalcones; Crystallography, X-Ray; Eucalyptus; Glucose Transporter Type 4; Models, Molecular; Molecular Structure; Plant Leaves; Rats; Xanthenes

2014
Optimized plant compound with potent anti-biofilm activity across gram-negative species.
    Bioorganic & medicinal chemistry, 2020, 03-01, Volume: 28, Issue:5

    Topics: Amines; Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2020
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha

2021
Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica.
    Connective tissue research, 1990, Volume: 24, Issue:2

    Topics: Cell Count; Cell Survival; Cells, Cultured; Collagen; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Humans; Hydroxyproline; Leucine; Male; Pentacyclic Triterpenes; Procollagen; Proline; RNA, Transfer, Pro; Terpenes; Triterpenes

1990
Influence of asiatic acid, madecassic acid, and asiaticoside on human collagen I synthesis.
    Planta medica, 1994, Volume: 60, Issue:2

    Topics: Adult; Carbohydrate Sequence; Cells, Cultured; Collagen; Humans; Molecular Sequence Data; Pentacyclic Triterpenes; Terpenes; Triterpenes

1994
Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer.
    Contact dermatitis, 1993, Volume: 29, Issue:4

    Topics: Adult; Animals; Dermatitis, Allergic Contact; Desensitization, Immunologic; Female; Guinea Pigs; Humans; Intradermal Tests; Patch Tests; Pentacyclic Triterpenes; Plant Extracts; Plants, Medicinal; Terpenes; Triterpenes

1993
Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds.
    European journal of dermatology : EJD, 1999, Volume: 9, Issue:4

    Topics: Animals; Collagen; DNA; Extracellular Matrix; Hydroxyproline; Male; Pentacyclic Triterpenes; Plants, Medicinal; Proteins; Rats; Rats, Sprague-Dawley; Skin; Terpenes; Triterpenes; Uronic Acids; Wound Healing

1999
Gene expression changes in the human fibroblast induced by Centella asiatica triterpenoids.
    Planta medica, 2003, Volume: 69, Issue:8

    Topics: Cell Line; Centella; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Pentacyclic Triterpenes; Phytotherapy; RNA; Terpenes; Triterpenes; Wound Healing

2003
Identification of triterpenoid compounds of Centella asiatica by thin-layer chromatography and mass spectrometry.
    Biomedical chromatography : BMC, 2006, Volume: 20, Issue:2

    Topics: Centella; Chromatography, Thin Layer; Mass Spectrometry; Pentacyclic Triterpenes; Terpenes; Triterpenes

2006
Molecular dynamics simulation and thermodynamic modeling of the self-assembly of the triterpenoids asiatic acid and madecassic acid in aqueous solution.
    The journal of physical chemistry. B, 2008, Feb-28, Volume: 112, Issue:8

    Topics: Computer Simulation; Micelles; Models, Chemical; Pentacyclic Triterpenes; Rotation; Solutions; Solvents; Surface-Active Agents; Terpenes; Thermodynamics; Time Factors; Triterpenes; Water

2008
Association (micellization) and partitioning of aglycon triterpenoids.
    Journal of colloid and interface science, 2008, Sep-15, Volume: 325, Issue:2

    Topics: Biological Assay; Carcinoma, Small Cell; Cell Line, Tumor; Chromatography, High Pressure Liquid; Computer Simulation; Glioblastoma; Humans; Inhibitory Concentration 50; Lung Neoplasms; Micelles; Molecular Conformation; Pentacyclic Triterpenes; Solubility; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Surface Tension; Triterpenes

2008
In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica.
    Journal of ethnopharmacology, 2010, Jul-20, Volume: 130, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Centella; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dealkylation; Dextromethorphan; Dose-Response Relationship, Drug; Enzyme Inhibitors; Herb-Drug Interactions; Humans; Hydroxylation; Kinetics; Methylation; Pentacyclic Triterpenes; Plant Extracts; Recombinant Proteins; Substrate Specificity; Testosterone; Tolbutamide; Triterpenes

2010
Factors affecting the content of pentacyclic triterpenes in Centella asiatica raw materials.
    Pharmaceutical biology, 2012, Volume: 50, Issue:12

    Topics: Agriculture; Centella; Chromatography, High Pressure Liquid; Ethanol; Flowers; Fruit; Microwaves; Pentacyclic Triterpenes; Plant Extracts; Plant Leaves; Plant Roots; Plants, Medicinal; Powders; Seasons; Solvents; Thailand; Triterpenes

2012
Metabolomic analysis of methyl jasmonate-induced triterpenoid production in the medicinal herb Centella asiatica (L.) urban.
    Molecules (Basel, Switzerland), 2013, Apr-11, Volume: 18, Issue:4

    Topics: Acetates; Centella; Chromatography, High Pressure Liquid; Cyclopentanes; Gas Chromatography-Mass Spectrometry; Metabolomics; Oxylipins; Pentacyclic Triterpenes; Plant Extracts; Plants, Medicinal; Triterpenes

2013
[Simultaneous determination of madecassoside, asiaticoside and their aglycones in Centella asiatica (L.) urban extracts by RP-HPLC].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2014, Volume: 43, Issue:2

    Topics: Centella; Chromatography, High Pressure Liquid; Pentacyclic Triterpenes; Plant Extracts; Reproducibility of Results; Triterpenes

2014
Structural analysis of metabolites of asiatic acid and its analogue madecassic acid in zebrafish using LC/IT-MSn.
    Molecules (Basel, Switzerland), 2015, Feb-12, Volume: 20, Issue:2

    Topics: Animals; Centella; Pentacyclic Triterpenes; Triterpenes; Zebrafish

2015
Comparison of three different extracts of Centella asiatica for anti-amnesic, antioxidant and anticholinergic activities: in vitro and in vivo study.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 105

    Topics: Amnesia; Animals; Antioxidants; Centella; Cholinergic Antagonists; Cholinesterase Inhibitors; Cholinesterases; Male; Memory Disorders; Methanol; Oxidants; Oxidative Stress; Pentacyclic Triterpenes; Plant Extracts; Rats; Rats, Wistar; Scopolamine; Triterpenes

2018