m 8218 has been researched along with cyclopentane in 7 studies
Studies (m 8218) | Trials (m 8218) | Recent Studies (post-2010) (m 8218) | Studies (cyclopentane) | Trials (cyclopentane) | Recent Studies (post-2010) (cyclopentane) |
---|---|---|---|---|---|
118 | 24 | 80 | 10,498 | 86 | 5,283 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (28.57) | 18.2507 |
2000's | 4 (57.14) | 29.6817 |
2010's | 1 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Gao, JH; Wen, GL; Zhang, QK | 1 |
Cheng, ZJ; Yang, ZP | 1 |
Chen, LF; Han, XY; Liu, CH; Liu, H; Liu, KL; Wu, B; Zhong, BH | 1 |
Huang, C; Jin, H; Wang, A; Wang, Z; Zhang, Q; Zhang, Z | 2 |
Wang, A; Wang, Z; Wei, J; Zhang, Q; Zhang, Z | 1 |
Gu, S; Li, M; Ma, T; Sun, X; Wang, Y | 1 |
7 other study(ies) available for m 8218 and cyclopentane
Article | Year |
---|---|
[Studies on the stereochemistry and structure-activity relationship of cholinolytic compounds 3-(2-phenyl-2-cyclopentyl-2-hydroxyl-ethoxy)-quinuclidines].
Topics: Animals; Cyclopentanes; Guinea Pigs; Mice; Parasympatholytics; Quinuclidines; Stereoisomerism; Structure-Activity Relationship | 1990 |
[The degradation mechanism of penequine hydrochloride in aqueous solutions].
Topics: Cyclopentanes; Drug Stability; Parasympatholytics; Quinuclidines; Solutions | 1993 |
Synthesis of the optical isomers of a new anticholinergic drug, penehyclidine hydrochloride (8018).
Topics: Cholinergic Antagonists; Cyclopentanes; Quinuclidines; Stereoisomerism | 2005 |
The pre- and post-natal toxicity of penequine hydrochloride in mice.
Topics: Administration, Oral; Animals; Animals, Newborn; Body Weight; Cholinergic Antagonists; Cyclopentanes; Dose-Response Relationship, Drug; Female; Gestational Age; Litter Size; Liver; Lung; Male; Mice; Molecular Structure; Organ Size; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Quinuclidines; Sex Factors; Sexual Behavior, Animal; Testis; Toxicity Tests | 2006 |
Embryo-fetal development toxicity of prenatal exposure to penequine hydrochloride intramuscularly in rats.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Cyclopentanes; Embryonic Development; Female; Fetal Development; Injections, Intramuscular; Male; No-Observed-Adverse-Effect Level; Quinuclidines; Rats; Rats, Wistar | 2007 |
Fertility and early embryonic development toxicity of penequine hydrochloride in mice.
Topics: Animals; Animals, Newborn; Body Weight; Cholinergic Antagonists; Cyclopentanes; Female; Fetal Development; Litter Size; Male; Mice; Mice, Inbred Strains; Organ Size; Pregnancy; Quinuclidines; Random Allocation; Sex Ratio; Sperm Count; Sperm Motility | 2007 |
Regulated hypoxia/reperfusion-dependent modulation of ERK1/2, cPLA2, and Bcl-2/Bax: a potential mechanism of neuroprotective effect of penehyclidine hydrochloride.
Topics: Analysis of Variance; Animals; bcl-2-Associated X Protein; Caspase 3; Cyclopentanes; Down-Regulation; Hippocampus; Hypoxia; In Vitro Techniques; Male; MAP Kinase Signaling System; Neuroprostanes; Phospholipases A2, Cytosolic; Proto-Oncogene Proteins c-bcl-2; Quinuclidines; Rats; Rats, Sprague-Dawley; Reperfusion | 2011 |