m 8218 has been researched along with atropine in 7 studies
| Studies (m 8218) | Trials (m 8218) | Recent Studies (post-2010) (m 8218) | Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) |
|---|---|---|---|---|---|
| 118 | 24 | 80 | 26,711 | 1,259 | 1,697 |
| Protein | Taxonomy | m 8218 (IC50) | atropine (IC50) |
|---|---|---|---|
| cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | 21.41 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.012 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.0067 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0007 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.0009 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.001 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0015 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.0021 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.354 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.012 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, YM; Liang, SW | 1 |
| Chen, S; Liao, Z; Meng, X; Mo, Z; Xiao, H; Yan, X | 1 |
| Chen, SJ; Liao, Z; Meng, XM; Mo, ZJ; Xiao, HT; Yan, XY | 1 |
| Lin, J; Luo, Z; Wei, XC | 1 |
| Lin, HQ; Wang, JR; Wang, KW | 1 |
| Yu, LQ; Zheng, XQ | 1 |
| Ailing, Y; Hongyu, X; Liwu, Z; Qingting, W; Xiaoling, S; Xin, L | 1 |
1 review(s) available for m 8218 and atropine
| Article | Year |
|---|---|
[Meta analysis of outcomes of penehyclidine hydrochloride and atropine in treatment of acute organophosphorus poisoning].
Topics: Atropine; Humans; Organophosphate Poisoning; Poisoning; Quinuclidines | 2010 |
3 trial(s) available for m 8218 and atropine
| Article | Year |
|---|---|
[Effects of penehyclidine hydrochloride or atropine combined with neostigmine for antagonizing residual neuromuscular block on patient's hemodynamics].
Topics: Abdomen; Adult; Anesthesia, General; Atropine; Blood Circulation; Female; Humans; Male; Neostigmine; Neuromuscular Blocking Agents; Quinuclidines | 2005 |
[Effect of penehyclidine hydrochloride as preoperation drug for elder on HRV].
Topics: Aged; Atropine; Electrocardiography; Female; Heart Rate; Humans; Male; Muscarinic Antagonists; Preoperative Care; Quinuclidines | 2008 |
Penehyclidine hydrochloride on postoperatively cognitive function.
Topics: Aged; Anesthesia, General; Atropine; Cholinergic Antagonists; Cognition; Cognitive Dysfunction; Cytokines; Delirium; Female; Humans; Incidence; Inflammation; Lung Neoplasms; Male; Mental Status and Dementia Tests; Postoperative Complications; Postoperative Period; Quinuclidines; Thoracoscopy; Treatment Outcome | 2019 |
3 other study(ies) available for m 8218 and atropine
| Article | Year |
|---|---|
Effects of the selective muscarinic receptor antagonist penehyclidine hydrochloride on the respiratory tract.
Topics: Animals; Atropine; Bronchoalveolar Lavage Fluid; Cyclic AMP; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle, Smooth, Vascular; Quinuclidines; Radioimmunoassay; Receptor, Muscarinic M2; Respiratory System | 2009 |
Characterization of the effect of penehyclidine hydrochloride on muscarinic receptor subtypes mediating the contraction of guinea-pig isolated gastrointestinal smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Cyclic AMP; Dose-Response Relationship, Drug; Female; Gastrointestinal Tract; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Quinuclidines; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M3 | 2009 |
[Clinical study of effect of penehyclidine hydrochloride and atropine sequential therapy in the treatment of severe acute organophosphorus pesticide poisoning].
Topics: Adolescent; Adult; Aged; Atropine; Female; Humans; Male; Middle Aged; Organophosphate Poisoning; Quinuclidines; Retrospective Studies; Young Adult | 2012 |