m 79175 has been researched along with ponalrestat in 6 studies
| Studies (m 79175) | Trials (m 79175) | Recent Studies (post-2010) (m 79175) | Studies (ponalrestat) | Trials (ponalrestat) | Recent Studies (post-2010) (ponalrestat) |
|---|---|---|---|---|---|
| 43 | 0 | 1 | 165 | 23 | 12 |
| Protein | Taxonomy | m 79175 (IC50) | ponalrestat (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.616 | |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 0.048 | |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | 0.022 | |
| Aldo-keto reductase family 1 member A1 | Sus scrofa (pig) | 2 | |
| Aldo-keto reductase family 1 member B1 | Sus scrofa (pig) | 0.021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poulsom, R | 4 |
| Hotta, N; Sakamoto, N | 1 |
| Kador, PF; Kinoshita, JH; Sharpless, NE | 1 |
2 review(s) available for m 79175 and ponalrestat
| Article | Year |
|---|---|
[Clinical application of aldose reductase inhibitors--prevention and therapy of diabetic complications].
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Humans; Imidazoles; Imidazolidines; L-Iditol 2-Dehydrogenase; Naphthalenes; Phthalazines; Sugar Alcohol Dehydrogenases | 1987 |
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution | 1985 |
4 other study(ies) available for m 79175 and ponalrestat
| Article | Year |
|---|---|
Inhibition of hexonate dehydrogenase and aldose reductase from bovine retina by sorbinil, statil, M79175 and valproate.
Topics: Aldehyde Reductase; Animals; Carbohydrate Dehydrogenases; Cattle; Imidazoles; Imidazolidines; In Vitro Techniques; Kinetics; Male; Molecular Conformation; Phthalazines; Pyridazines; Retina; Sugar Alcohol Dehydrogenases; Valproic Acid; Vitamin K | 1986 |
Inhibition of aldose reductase from human retina.
Topics: Aged; Aldehyde Reductase; Chemical Fractionation; Chromatography; Humans; Imidazoles; Imidazolidines; Middle Aged; Phthalazines; Retina; Sugar Alcohol Dehydrogenases | 1987 |
Comparison of aldose reductase inhibitors in vitro. Effects of enzyme purification and substrate type.
Topics: Aldehyde Reductase; Animals; Benzaldehydes; Cattle; Glucose; Imidazoles; Imidazolidines; Lens, Crystalline; Phthalazines; Sugar Alcohol Dehydrogenases | 1987 |
Aldose reductases from human retina and bovine lens: dependence of inhibition upon the choice of enzyme substrate.
Topics: Aldehyde Reductase; Animals; Cattle; Female; Humans; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Male; Phthalazines; Quercetin; Retina; Substrate Specificity; Sugar Alcohol Dehydrogenases | 1987 |