Page last updated: 2024-09-03

m 79175 and ponalrestat

m 79175 has been researched along with ponalrestat in 6 studies

Compound Research Comparison

Studies
(m 79175)
Trials
(m 79175)
Recent Studies (post-2010)
(m 79175)
Studies
(ponalrestat)
Trials
(ponalrestat)
Recent Studies (post-2010) (ponalrestat)
43011652312

Protein Interaction Comparison

ProteinTaxonomym 79175 (IC50)ponalrestat (IC50)
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.616
Aldo-keto reductase family 1 member B1Homo sapiens (human)0.048
Aldo-keto reductase family 1 member B1Bos taurus (cattle)0.022
Aldo-keto reductase family 1 member A1Sus scrofa (pig)2
Aldo-keto reductase family 1 member B1Sus scrofa (pig)0.021

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Poulsom, R4
Hotta, N; Sakamoto, N1
Kador, PF; Kinoshita, JH; Sharpless, NE1

Reviews

2 review(s) available for m 79175 and ponalrestat

ArticleYear
[Clinical application of aldose reductase inhibitors--prevention and therapy of diabetic complications].
    Nihon rinsho. Japanese journal of clinical medicine, 1987, Volume: 45, Issue:12

    Topics: Aldehyde Reductase; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Humans; Imidazoles; Imidazolidines; L-Iditol 2-Dehydrogenase; Naphthalenes; Phthalazines; Sugar Alcohol Dehydrogenases

1987
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution

1985

Other Studies

4 other study(ies) available for m 79175 and ponalrestat

ArticleYear
Inhibition of hexonate dehydrogenase and aldose reductase from bovine retina by sorbinil, statil, M79175 and valproate.
    Biochemical pharmacology, 1986, Sep-01, Volume: 35, Issue:17

    Topics: Aldehyde Reductase; Animals; Carbohydrate Dehydrogenases; Cattle; Imidazoles; Imidazolidines; In Vitro Techniques; Kinetics; Male; Molecular Conformation; Phthalazines; Pyridazines; Retina; Sugar Alcohol Dehydrogenases; Valproic Acid; Vitamin K

1986
Inhibition of aldose reductase from human retina.
    Current eye research, 1987, Volume: 6, Issue:3

    Topics: Aged; Aldehyde Reductase; Chemical Fractionation; Chromatography; Humans; Imidazoles; Imidazolidines; Middle Aged; Phthalazines; Retina; Sugar Alcohol Dehydrogenases

1987
Comparison of aldose reductase inhibitors in vitro. Effects of enzyme purification and substrate type.
    Biochemical pharmacology, 1987, May-15, Volume: 36, Issue:10

    Topics: Aldehyde Reductase; Animals; Benzaldehydes; Cattle; Glucose; Imidazoles; Imidazolidines; Lens, Crystalline; Phthalazines; Sugar Alcohol Dehydrogenases

1987
Aldose reductases from human retina and bovine lens: dependence of inhibition upon the choice of enzyme substrate.
    Progress in clinical and biological research, 1987, Volume: 232

    Topics: Aldehyde Reductase; Animals; Cattle; Female; Humans; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Male; Phthalazines; Quercetin; Retina; Substrate Specificity; Sugar Alcohol Dehydrogenases

1987