Page last updated: 2024-09-03

m 79175 and imidazolidines

m 79175 has been researched along with imidazolidines in 42 studies

Compound Research Comparison

Studies (m 79175)	Trials (m 79175)	Recent Studies (post-2010) (m 79175)	Studies (imidazolidines)	Trials (imidazolidines)	Recent Studies (post-2010) (imidazolidines)
43	0	1	1,666	186	358

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (64.29)	18.7374
1990's	12 (28.57)	18.2507
2000's	2 (4.76)	29.6817
2010's	1 (2.38)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Johnson, MJ; Tsui, JY; Unakar, NJ	2
Dang, L; Johnson, M; Tsui, JY; Unakar, NJ	1
Okamura, R; Taura, T; Teshima, R	2
Kador, PF; Sato, S; Takahashi, Y; Wyman, M	2
Akagi, Y; Kador, PF	1
Akagi, Y; Ikebe, H; Kador, PF; Kinoshita, JH; Takahashi, Y; Wyman, M	1
Johnson, M; Tsui, J; Unakar, N	1
Ashizawa, K	1
Kojima, M; Sasaki, K	2
Poulsom, R	4
Wada, E	1
Akagi, Y; Ikebe, H; Majima, K; Miyamoto, Y; Miyatani, H; Takahashi, Y; Tanabe, T; Terubayashi, H	1
Akagi, Y; Chamoto, K; Ikebe, H; Miyamoto, Y; Takahashi, Y; Tasaka, H; Terubayashi, H; Yoshikawa, T	1
Iriyama, K; Matsuzaki, H; Mizuno, A; Nozawa, H; Ozaki, Y; Yaginuma, T	1
Arimori, K; Iwaoku, R; Mishima, M; Nakano, M	1
Fujinaga, Y; Funada, M; Okamoto, I; Yamana, T	2
Kojima, M; Sasaki, K; Taniguchi, T	1
Hotta, N; Sakamoto, N	1
Mizuno, A; Nozawa, H; Yaginuma, T	1
Iwata, S; Kamiya, M; Majima, Y	1
Ishibashi, Y; Iwata, S; Kato, A; Miyake, Y	1
Horie, T; Ishibashi, Y; Iwata, S; Kato, A; Miyake, Y	1
Akagi, Y; Ikebe, H; Kador, PF; Kinoshita, JH; Terubayashi, H	1
Ashizawa, K; Hattori, T; Miyake, Y; Sato, T; Uchikawa, K	1
Akagi, Y; Kador, PF; Kinoshita, JH; Terubayashi, H; Wyman, M	1
Kador, PF; Kinoshita, JH; Sharpless, NE	1
Hayano, S; Nozawa, Y; Ono, H	1
Anthony, P; Johnson, M; Tsui, J; Unakar, NJ	1
Augustin, W; Kador, PF; Takahashi, Y; Wyman, M	1
Kador, PF; Neuenschwander, H; Takahashi, Y	1
Kador, PF; Mori, K; Sato, S; Wyman, M	1
Chan, CC; Chew, EY; Cox, TA; Cusick, M; Ferris, F; Kador, PF	1
Babb, T; Blessing, K; Kador, PF; Kompella, UB; Koushik, K; Randazzo, J; Takamura, Y; Zhu, W	1
Kador, PF; Oates, PJ; Wyman, M	1

Reviews

3 review(s) available for m 79175 and imidazolidines

Article	Year
[Clinical application of aldose reductase inhibitors--prevention and therapy of diabetic complications]. Nihon rinsho. Japanese journal of clinical medicine, 1987, Volume: 45, Issue:12 Topics: Aldehyde Reductase; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Humans; Imidazoles; Imidazolidines; L-Iditol 2-Dehydrogenase; Naphthalenes; Phthalazines; Sugar Alcohol Dehydrogenases	1987
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications. Journal of medicinal chemistry, 1985, Volume: 28, Issue:7 Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution	1985
Aldose reductase, ocular diabetic complications and the development of topical Kinostat(®). Progress in retinal and eye research, 2016, Volume: 54 Topics: Administration, Topical; Aldehyde Reductase; Animals; Cataract; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Enzyme Inhibitors; Humans; Imidazolidines; Ophthalmic Solutions	2016

Other Studies

39 other study(ies) available for m 79175 and imidazolidines

Article	Year
Effect of aldose reductase inhibitors on lenticular dulcitol level in galactose fed rats. Journal of ocular pharmacology, 1992,Fall, Volume: 8, Issue:3 Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Sprague-Dawley	1992
In utero and milk-mediated effect of aldose reductase inhibitor on galactose cataracts. Experimental eye research, 1991, Volume: 53, Issue:5 Topics: Aldehyde Reductase; Animals; Cataract; Female; Fetal Diseases; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Maternal-Fetal Exchange; Microscopy, Electron, Scanning; Milk, Human; Pregnancy; Rats; Rats, Inbred Strains	1991
Inhibition in rat of development of in utero galactose-induced cataract by an aldose reductase inhibitor--a light microscopic study. Japanese journal of ophthalmology, 1991, Volume: 35, Issue:3 Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Female; Fetal Diseases; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains	1991
Progression of sugar cataract in the dog. Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:6 Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Galactose; Humans; Imidazoles; Imidazolidines; Lens, Crystalline; Photography; Random Allocation; Rats; Rats, Inbred Strains	1991
Effect of aldose reductase inhibitors on the progression of retinopathy in galactose-fed dogs. Experimental eye research, 1990, Volume: 50, Issue:6 Topics: Aldehyde Reductase; Animals; Diabetic Retinopathy; Dietary Carbohydrates; Dogs; Galactose; Imidazoles; Imidazolidines; Retinal Vessels; Sugar Alcohol Dehydrogenases	1990
Prevention of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by aldose reductase inhibitors. Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:9 Topics: Aldehyde Reductase; Aneurysm; Animals; Capillaries; Diabetic Retinopathy; Dogs; Dose-Response Relationship, Drug; Female; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Retinal Vessels; Sugar Alcohol Dehydrogenases	1990
Aldose reductase inhibitors and prevention of galactose cataracts in rats. Investigative ophthalmology & visual science, 1989, Volume: 30, Issue:7 Topics: Aldehyde Reductase; Animals; Cataract; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Sugar Alcohol Dehydrogenases; Time Factors	1989
Prefeeding of aldose reductase inhibitor and galactose cataractogenesis. Current eye research, 1989, Volume: 8, Issue:10 Topics: Aldehyde Reductase; Animals; Cataract; Diet; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Sugar Alcohol Dehydrogenases	1989
Polymorphism and crystal structure of 2R,4S,6-fluoro-2-methyl-spiro[chroman-4,4'-imidazoline]-2',5-dione (M79175). Journal of pharmaceutical sciences, 1989, Volume: 78, Issue:3 Topics: Crystallization; Imidazoles; Imidazolidines; Molecular Conformation; X-Ray Diffraction	1989
[A study of the limitations of ARI treatment of streptozotocin-induced diabetic cataracts]. Nippon Ganka Gakkai zasshi, 1986, Volume: 90, Issue:12 Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Imidazoles; Imidazolidines; Male; Rats; Rats, Inbred Strains; Streptozocin; Sugar Alcohol Dehydrogenases	1986
Inhibition of hexonate dehydrogenase and aldose reductase from bovine retina by sorbinil, statil, M79175 and valproate. Biochemical pharmacology, 1986, Sep-01, Volume: 35, Issue:17 Topics: Aldehyde Reductase; Animals; Carbohydrate Dehydrogenases; Cattle; Imidazoles; Imidazolidines; In Vitro Techniques; Kinetics; Male; Molecular Conformation; Phthalazines; Pyridazines; Retina; Sugar Alcohol Dehydrogenases; Valproic Acid; Vitamin K	1986
r-Galactonolactone in experimental galactosemic animals. Archives of biochemistry and biophysics, 1986, Nov-15, Volume: 251, Issue:1 Topics: Aldehyde Reductase; Animals; Galactose; Galactosemias; Guinea Pigs; Imidazoles; Imidazolidines; Lactones; Liver; Male; Metabolic Clearance Rate; Oxidation-Reduction; Tissue Distribution	1986
Inhibition of aldose reductase from human retina. Current eye research, 1987, Volume: 6, Issue:3 Topics: Aged; Aldehyde Reductase; Chemical Fractionation; Chromatography; Humans; Imidazoles; Imidazolidines; Middle Aged; Phthalazines; Retina; Sugar Alcohol Dehydrogenases	1987
Comparison of aldose reductase inhibitors in vitro. Effects of enzyme purification and substrate type. Biochemical pharmacology, 1987, May-15, Volume: 36, Issue:10 Topics: Aldehyde Reductase; Animals; Benzaldehydes; Cattle; Glucose; Imidazoles; Imidazolidines; Lens, Crystalline; Phthalazines; Sugar Alcohol Dehydrogenases	1987
[Prevention of experimental diabetic corneal endotheliopathy with aldose reductase inhibitor]. Nippon Ganka Gakkai zasshi, 1987, Volume: 91, Issue:2 Topics: Aldehyde Reductase; Animals; Cornea; Corneal Diseases; Diabetes Mellitus, Experimental; Histocytochemistry; Imidazoles; Imidazolidines; Microscopy, Electron; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases	1987
[Prevention of rat galactose cataract with topical aldose reductase inhibitor, E-1008]. Nippon Ganka Gakkai zasshi, 1987, Volume: 91, Issue:2 Topics: Aldehyde Reductase; Animals; Cataract; Galactosemias; Histocytochemistry; Imidazoles; Imidazolidines; Lens, Crystalline; Ophthalmic Solutions; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases	1987
Aldose reductases from human retina and bovine lens: dependence of inhibition upon the choice of enzyme substrate. Progress in clinical and biological research, 1987, Volume: 232 Topics: Aldehyde Reductase; Animals; Cattle; Female; Humans; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Male; Phthalazines; Quercetin; Retina; Substrate Specificity; Sugar Alcohol Dehydrogenases	1987
Effect of aldose reductase inhibitor on experimental diabetic cataract monitored by laser Raman spectroscopy. Experimental eye research, 1987, Volume: 45, Issue:1 Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Imidazoles; Imidazolidines; Male; Rats; Spectrum Analysis, Raman; Sugar Alcohol Dehydrogenases	1987
Evaluation of orally administered activated charcoal on intestinal dialysis of intravenously administered M79175, an aldose reductase inhibitor, in rats. Journal of pharmacobio-dynamics, 1987, Volume: 10, Issue:6 Topics: Administration, Oral; Aldehyde Reductase; Animals; Biological Transport; Charcoal; Imidazoles; Imidazolidines; Intestinal Mucosa; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases	1987
Effects of aldose reductase inhibitor (M79175) on ERG oscillatory potential abnormalities in streptozotocin fructose-induced diabetes in rats. Japanese journal of ophthalmology, 1987, Volume: 31, Issue:2 Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinography; Imidazoles; Imidazolidines; Male; Rats; Rats, Inbred Strains; Retina; Sugar Alcohol Dehydrogenases	1987
[The intraocular penetration of ARI (M-79175) in rabbit eyes]. Nippon Ganka Gakkai zasshi, 1987, Volume: 91, Issue:6 Topics: Aldehyde Reductase; Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Imidazoles; Imidazolidines; Rabbits; Sugar Alcohol Dehydrogenases	1987
Raman spectroscopic study of the effect of aldose reductase inhibitor on experimental diabetic cataract. Nippon Ganka Gakkai zasshi, 1988, Volume: 92, Issue:1 Topics: Aldehyde Reductase; Animals; Body Water; Cataract; Diabetes Mellitus, Experimental; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Rats; Rats, Inbred Strains; Spectrum Analysis, Raman; Sugar Alcohol Dehydrogenases	1988
[The intraocular penetration of aldose reductase inhibitor in rat eyes]. Nippon Ganka Gakkai zasshi, 1988, Volume: 92, Issue:1 Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Eye; Imidazoles; Imidazolidines; Male; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases; Tissue Distribution	1988
[Cytological aspects of sugar-induced cataract formation]. Nippon Ganka Gakkai zasshi, 1988, Volume: 92, Issue:2 Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Galactose; Imidazoles; Imidazolidines; Male; Rats; Rats, Inbred Strains; Vitamin E	1988
Corneal permeability of aldose reductase inhibitor, M79175. I. In vitro study using corneal permeability apparatus. Journal of ocular pharmacology, 1986,Summer, Volume: 2, Issue:3 Topics: Aldehyde Reductase; Animals; Benzalkonium Compounds; Cornea; Hydrogen-Ion Concentration; Imidazoles; Imidazolidines; In Vitro Techniques; Permeability; Rabbits; Sugar Alcohol Dehydrogenases	1986
Corneal permeability of aldose reductase inhibitor, M79175. II. In vivo study on pharmacokinetic aspect. Journal of ocular pharmacology, 1986,Summer, Volume: 2, Issue:3 Topics: Aldehyde Reductase; Animals; Cornea; Female; Hydrogen-Ion Concentration; Imidazoles; Imidazolidines; Male; Pilocarpine; Rabbits; Sugar Alcohol Dehydrogenases	1986
[Prevention of pericyte ghost formation in retinal capillaries by aldose reductase inhibitor in galactose-fed dogs with diabetic retinopathy]. Nippon Ganka Gakkai zasshi, 1988, Volume: 92, Issue:9 Topics: Aldehyde Reductase; Animals; Capillaries; Diabetic Retinopathy; Dogs; Galactose; Imidazoles; Imidazolidines; Male; Retinal Vessels; Sugar Alcohol Dehydrogenases	1988
Polymorphic differences in alpha- and beta-form crystals of 2R, 4S, 6-fluoro-2-methyl-spiro[chroman-4,4'-imidazoline]-2',5-dione (M79175) as determined by X-ray diffraction, infrared spectroscopy, and differential scanning calorimetry. Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:7 Topics: Calorimetry, Differential Scanning; Crystallization; Imidazoles; Imidazolidines; Molecular Conformation; Polymers; Spectrophotometry, Infrared; X-Ray Diffraction	1988
Prevention of pericyte ghost formation in retinal capillaries of galactose-fed dogs by aldose reductase inhibitors. Archives of ophthalmology (Chicago, Ill. : 1960), 1988, Volume: 106, Issue:8 Topics: Animals; Capillaries; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dogs; Imidazoles; Imidazolidines; Male; Retinal Vessels	1988
[Effect of aldose reductase inhibitor (M79175) on the oscillatory potential in ERG of streptozotocin-fructose induced diabetic rats]. Nippon Ganka Gakkai zasshi, 1985, Volume: 89, Issue:10 Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Electroretinography; Imidazoles; Imidazolidines; Male; Rats; Rats, Inbred Strains; Retina; Sugar Alcohol Dehydrogenases	1985
[Effects of M79175, an aldose reductase inhibitor, on experimental sugar cataracts]. Nippon Ganka Gakkai zasshi, 1982, Volume: 86, Issue:9 Topics: Aldehyde Reductase; Animals; Cataract; Cattle; Diabetes Mellitus, Experimental; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Rats; Sorbitol; Sugar Alcohol Dehydrogenases	1982
Amelioration of diabetes-like retinal changes in galactose-fed dogs. Preventive medicine, 1994, Volume: 23, Issue:5 Topics: Aldehyde Reductase; Animals; Cataract; Diabetic Retinopathy; Dogs; Dose-Response Relationship, Drug; Galactose; Imidazoles; Imidazolidines; Male; Retina; Retinal Vessels	1994
Aldose reductase inhibitors and galactose toxicity in neonatal and maternal rat lenses. Journal of ocular pharmacology, 1993,Winter, Volume: 9, Issue:4 Topics: Aldehyde Reductase; Animals; Animals, Newborn; Cataract; Female; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Sprague-Dawley	1993
Quantitative analysis of retinal vessel changes in galactose-fed dogs. Journal of ocular pharmacology, 1993,Fall, Volume: 9, Issue:3 Topics: Aldehyde Reductase; Animals; Cataract; Cell Count; Diabetic Retinopathy; Dogs; Endothelium, Vascular; Galactose; Image Processing, Computer-Assisted; Imidazoles; Imidazolidines; Male; Retinal Vessels	1993
Inhibition of in utero galactose-induced cataract development by an aldose reductase inhibitor in rat--electron microscopic study. Japanese journal of ophthalmology, 1993, Volume: 37, Issue:2 Topics: Aldehyde Reductase; Animals; Animals, Newborn; Cataract; Female; Fetal Diseases; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Pregnancy; Rats; Rats, Sprague-Dawley; Vacuoles	1993
Dose-dependent reduction of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by the aldose reductase inhibitor M79175. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1997, Volume: 13, Issue:6 Topics: Aldehyde Reductase; Animals; Cataract; Diabetic Retinopathy; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Galactose; Imidazoles; Imidazolidines; Male; Retinal Vessels; Trypsin	1997
Dose-dependent prevention of sugar cataracts in galactose-fed dogs by the aldose reductase inhibitor M79175. Experimental eye research, 1998, Volume: 66, Issue:2 Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Galactose; Imidazoles; Imidazolidines; Male	1998
Effects of aldose reductase inhibitors and galactose withdrawal on fluorescein angiographic lesions in galactose-fed dogs. Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:12 Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetic Retinopathy; Disease Models, Animal; Disease Progression; Dogs; Enzyme Inhibitors; Fluorescein Angiography; Galactose; Imidazoles; Imidazolidines; Male; Retinal Neovascularization; Retinal Vessels	2003
Topical aldose reductase inhibitor formulations for effective lens drug delivery in a rat model for sugar cataracts. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:2 Topics: Administration, Topical; Aldehyde Reductase; Animals; Aqueous Humor; Biological Availability; Biological Transport; Cataract; Cornea; Drug Carriers; Enzyme Inhibitors; Galactose; Hydrogen-Ion Concentration; Imidazolidines; Lens, Crystalline; Male; Mydriasis; Ophthalmic Solutions; Pharmaceutical Vehicles; Rats; Rats, Sprague-Dawley; Vacuoles; Viscosity	2007