lysophosphatidic acid has been researched along with transforming growth factor beta in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (37.04) | 29.6817 |
| 2010's | 16 (59.26) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Anzano, MB; Fujii, M; Kleuser, B; Roberts, AB; Sauer, B; Schäfer-Korting, M; Vogler, R; Zimmermann, K | 1 |
| Hatamochi, A; Sato, M; Shegogue, D; Trojanowska, M; Yamazaki, S | 1 |
| Watsky, MA; Yin, Z | 1 |
| Hammer, S; Kleuser, B; Radeke, HH; Sauer, B; Stoidtner, K; von Wenckstern, H | 1 |
| Atilla, G; Black, SA; Emingil, G; Firatli, E; Hasturk, H; Kantarci, A; Lee, A; Murawel, P; Sheff, M; Trackman, PC; Uchida, Y; Uzel, MI; Van Dyke, TE; Xydas, CE; Yucekal-Tuncer, B | 1 |
| Dettman, RW; Dokic, D | 1 |
| Asano, M; Asano, T; Ito, H; Kato, K; Morishita, R; Nagata, K; Shinohara, H; Ueda, H | 1 |
| Bascands, JL; Calise, D; Chun, J; Grès, S; Guigné, C; Klein, J; Neau, E; Pradère, JP; Saulnier-Blache, JS; Schanstra, JP; Valet, P | 1 |
| Brandan, E; Cabello-Verrugio, C; Cañón, P; Fadic, R; Vial, C; Zúñiga, LM | 1 |
| Jenkins, G; Knox, AJ; Maher, TM; McAnulty, RJ; Porte, J; Sheppard, D; Violette, SM; Weinreb, PH; Xu, MY | 1 |
| Kikuchi-Handa, T; Nogawa, H; Okamoto, K | 1 |
| Fang, X; Lebman, DA; Mukherjee, A; Wu, J | 1 |
| Heo, SC; Kim, IS; Kim, J; Kim, JH; Kim, YM; Kwon, YW; Lee, TG; Shin, SH | 1 |
| Giacomini, MM; Kudo, M; Sheppard, D; Travis, MA | 1 |
| Jeon, ES; Kim, EK; Kim, JH; Ryu, H | 1 |
| Geng, H; Gilchrist, A; Lan, R; Saikumar, P; Singha, PK; Venkatachalam, MA; Violette, SM; Weinberg, JM; Weinreb, PH | 1 |
| Do, EK; Heo, SC; Kim, JH; Kim, KH; Kim, YM; Kwon, YW; Shin, SH; Suh, DS; Yoon, MS | 1 |
| Bascands, JL; Bouloumié, A; Decaunes, P; Gres, S; Langin, D; Rancoule, C; Saulnier-Blache, JS; Valet, P; Viaud, M; Viguerie, N | 1 |
| Amin, MA; Campbell, P; Fox, DA; Haak, AJ; Khanna, D; Larsen, SD; Neubig, RR; Ruth, JH; Tsou, PS | 1 |
| Cheng, J; Wang, Y; Xie, Y; Zong, C | 1 |
| Li, J; Sun, X; Wang, G | 1 |
| Cheng, J; Xie, Y; Zhang, X; Zong, C | 1 |
| Choi, JW; Jun, HS; Jung, JY; Li, HY; Oh, YS | 1 |
| Hino, K; Horigome, K; Ikeya, M; Jin, Y; Kawakami, K; Komura, S; Nagata, S; Nishio, M; Ohta, A; Toguchida, J; Yamada, Y; Zhao, C | 1 |
| Deng, S; Huai, G; Liu, Y; Peng, J; Qi, P; Shi, W; Wang, H; Wang, X; Wang, Y; Yang, H | 1 |
| Faraji, F; Gilliard, C; Hunter, K; Kelly, K; Ku, KP; Lake, R; Lang, J; Martin, P; Niles, D; Rodems, T; Sowalsky, AG; Sperger, J; Tillman, H; Ward, Y; Yin, J | 1 |
| Jun, HS; Kim, D; Nam, GY; Seo, E | 1 |
1 review(s) available for lysophosphatidic acid and transforming growth factor beta
| Article | Year |
|---|---|
Mutual regulation of the Hippo/Wnt/LPA/TGF‑β signaling pathways and their roles in glaucoma (Review).
Topics: Animals; Glaucoma; Humans; Lysophospholipids; Models, Biological; Signal Transduction; Transforming Growth Factor beta; Wnt Proteins | 2018 |
1 trial(s) available for lysophosphatidic acid and transforming growth factor beta
| Article | Year |
|---|---|
Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence.
Topics: Actins; Adipose Tissue; Animals; Collagen; Enzyme Activators; Female; Fibrosis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Isoxazoles; Lysophospholipids; Male; Mice; Mice, Obese; Propionates; Receptors, Lysophosphatidic Acid; Tissue Culture Techniques; Transforming Growth Factor beta | 2014 |
25 other study(ies) available for lysophosphatidic acid and transforming growth factor beta
| Article | Year |
|---|---|
Lysophosphatidic acid interacts with transforming growth factor-beta signaling to mediate keratinocyte growth arrest and chemotaxis.
Topics: Cell Division; Cells, Cultured; Chemotaxis; DNA-Binding Proteins; Drug Interactions; Growth Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Keratinocytes; Lysophospholipids; Signal Transduction; Smad3 Protein; Trans-Activators; Transforming Growth Factor beta | 2004 |
Lysophosphatidic acid inhibits TGF-beta-mediated stimulation of type I collagen mRNA stability via an ERK-dependent pathway in dermal fibroblasts.
Topics: Blotting, Northern; Cells, Cultured; Collagen; Collagen Type I; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Humans; Immunoprecipitation; Luciferases; Lysophospholipids; Platelet-Derived Growth Factor; RNA; RNA, Messenger; Time Factors; Transfection; Transforming Growth Factor beta | 2004 |
Chloride channel activity in human lung fibroblasts and myofibroblasts.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Actins; Adenosine Triphosphate; Cell Differentiation; Cells, Cultured; Chloride Channels; Electrophysiology; Fetus; Fibroblasts; Humans; Lung; Lysophospholipids; Muscle, Smooth; Nitrobenzoates; Receptors, Lysophosphatidic Acid; Sphingosine; Transforming Growth Factor beta | 2005 |
Overlapping signaling pathways of sphingosine 1-phosphate and TGF-beta in the murine Langerhans cell line XS52.
Topics: Animals; Cell Differentiation; Cell Line; Chemotactic Factors; Chemotaxis; DNA-Binding Proteins; Langerhans Cells; Lysophospholipids; Mice; Receptors, Lysosphingolipid; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Smad Proteins; Smad3 Protein; Sphingosine; Trans-Activators; Transforming Growth Factor beta | 2005 |
Epithelial and connective tissue cell CTGF/CCN2 expression in gingival fibrosis.
Topics: Adult; Cells, Cultured; Connective Tissue Cells; Connective Tissue Growth Factor; Epithelial Cells; Fibroblasts; Fibromatosis, Gingival; Fibrosis; Gingiva; Humans; Immediate-Early Proteins; Immunohistochemistry; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Transforming Growth Factor beta | 2006 |
VCAM-1 inhibits TGFbeta stimulated epithelial-mesenchymal transformation by modulating Rho activity and stabilizing intercellular adhesion in epicardial mesothelial cells.
Topics: Actin Cytoskeleton; Animals; beta Catenin; Cadherins; Cell Adhesion; Cell Differentiation; Cells, Cultured; Chick Embryo; Epithelial Cells; Intercellular Junctions; Lysophospholipids; Pericardium; Phosphorylation; Protein Isoforms; Rats; rho GTP-Binding Proteins; Stress Fibers; Transforming Growth Factor beta; Vascular Cell Adhesion Molecule-1 | 2006 |
Expression of smooth muscle cell-specific proteins in neural progenitor cells induced by agonists of G protein-coupled receptors and transforming growth factor-beta.
Topics: Actins; Animals; Carbachol; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Endothelins; Gene Expression Regulation, Developmental; Lysophospholipids; Neurons; Prosencephalon; Rats; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Time Factors; Transfection; Transforming Growth Factor beta | 2007 |
LPA1 receptor activation promotes renal interstitial fibrosis.
Topics: Animals; Culture Media, Conditioned; Fibrosis; Humans; Isoxazoles; Kidney; Kidney Diseases; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phospholipids; Propionates; Receptors, Lysophosphatidic Acid; Transforming Growth Factor beta; Ureter | 2007 |
Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation.
Topics: Animals; Biological Transport; Cell Dedifferentiation; Cell Differentiation; Cell Line; Cell Nucleus; Connective Tissue Growth Factor; Cytoskeleton; Desmin; Down-Regulation; Extracellular Matrix Proteins; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; MyoD Protein; Myogenin; Myosins; Recombinant Proteins; Transforming Growth Factor beta | 2008 |
Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).
Topics: Animals; Antigens, Neoplasm; Blotting, Western; Coculture Techniques; Fibrosis; Flow Cytometry; Fluorescent Antibody Technique; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Immunohistochemistry; Integrins; Lung; Lung Injury; Lysophospholipids; Mice; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta | 2009 |
Evidence of interlobular repulsion during branching morphogenesis in mouse salivary glands.
Topics: Animals; Cell Movement; Cell Proliferation; Epithelium; Fibroblast Growth Factor 1; Lysophospholipids; Mice; Morphogenesis; Neuregulin-1; Organ Culture Techniques; Salivary Glands; Submandibular Gland; Transforming Growth Factor beta | 2010 |
Lysophosphatidic acid-induced p21Waf1 expression mediates the cytostatic response of breast and ovarian cancer cells to TGFβ.
Topics: Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Drug Synergism; Female; Humans; Immunohistochemistry; Lysophospholipids; Ovarian Neoplasms; Phosphorylation; Transforming Growth Factor beta | 2011 |
Proteomic identification of betaig-h3 as a lysophosphatidic acid-induced secreted protein of human mesenchymal stem cells: paracrine activation of A549 lung adenocarcinoma cells by betaig-h3.
Topics: Adenocarcinoma; Adipose Tissue; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Culture Media, Conditioned; Extracellular Matrix Proteins; Humans; Lung Neoplasms; Lysophospholipids; Mesenchymal Stem Cells; Paracrine Communication; Proteome; Proteomics; Receptors, Lysophosphatidic Acid; rho-Associated Kinases; Tandem Mass Spectrometry; Transforming Growth Factor beta; Tumor Cells, Cultured | 2012 |
Epithelial cells utilize cortical actin/myosin to activate latent TGF-β through integrin α(v)β(6)-dependent physical force.
Topics: Actins; Antigens, Neoplasm; Cells, Cultured; Epithelial Cells; Humans; Integrins; Lysophospholipids; Myosins; Signal Transduction; Sphingosine; Transforming Growth Factor beta | 2012 |
Lysophosphatidic acid activates TGFBIp expression in human corneal fibroblasts through a TGF-β1-dependent pathway.
Topics: Cell Line; Cells, Cultured; Cornea; Corneal Dystrophies, Hereditary; Extracellular Matrix Proteins; Fibroblasts; Humans; Lysophospholipids; MAP Kinase Kinase 4; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2012 |
Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β.
Topics: Animals; Antigens, Neoplasm; Cell Nucleus; Connective Tissue Growth Factor; Cytokines; Fibrosis; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Integrins; Kidney Tubules, Proximal; Lipids; Lysophospholipids; Male; Mice; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid; Regeneration; Reperfusion Injury; rho GTP-Binding Proteins; RNA, Messenger; Signal Transduction; Smad2 Protein; Time Factors; Transforming Growth Factor beta | 2012 |
Lysophosphatidic acid-induced ADAM12 expression mediates human adipose tissue-derived mesenchymal stem cell-stimulated tumor growth.
Topics: Actins; ADAM Proteins; ADAM12 Protein; Adenocarcinoma; Adenocarcinoma of Lung; Adipose Tissue; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Culture Media, Conditioned; Extracellular Matrix Proteins; Fibroblasts; Gene Silencing; Humans; Lung Neoplasms; Lysophospholipids; Membrane Proteins; Mesenchymal Stem Cells; Mice; Mice, Nude; Neoplasms; Receptors, Lysophosphatidic Acid; RNA, Small Interfering; Transforming Growth Factor beta; Xenograft Model Antitumor Assays | 2012 |
Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury.
Topics: Animals; Cell Culture Techniques; Cell Proliferation; Collagen Type I; Connective Tissue Growth Factor; Disease Models, Animal; DNA-Binding Proteins; Female; Humans; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Middle Aged; Myofibroblasts; NIH 3T3 Cells; Nipecotic Acids; Oncogene Proteins, Fusion; Scleroderma, Systemic; Serum Response Factor; Trans-Activators; Transcription, Genetic; Transforming Growth Factor beta | 2014 |
Transforming growth factor-Beta inhibits heme oxygenase-1 expression in lung fibroblast through nuclear factor-kappa-B-dependent pathway.
Topics: Animals; Blotting, Western; Cell Differentiation; Fibroblasts; Gene Expression Regulation; Gene Knockdown Techniques; Heme Oxygenase-1; Humans; Lung; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Pulmonary Fibrosis; Transcription Factor RelA; Transforming Growth Factor beta | 2014 |
Transforming growth factor β regulates β-catenin expression in lung fibroblast through NF-κB dependent pathway.
Topics: Animals; beta Catenin; Bleomycin; Cell Differentiation; Cell Line; Fibroblasts; Humans; Lung; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Pulmonary Fibrosis; Transforming Growth Factor beta; Up-Regulation | 2014 |
Transforming growth factor-β inhibits IQ motif containing guanosine triphosphatase activating protein 1 expression in lung fibroblasts via the nuclear factor-κB signaling pathway.
Topics: Animals; Bleomycin; Cell Differentiation; Fibroblasts; Gene Expression Regulation; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lysophospholipids; Mice; NF-kappa B; ras GTPase-Activating Proteins; Signal Transduction; Transforming Growth Factor beta | 2015 |
Blocking lysophosphatidic acid receptor 1 signaling inhibits diabetic nephropathy in db/db mice.
Topics: Animals; Cell Line; Diabetes Mellitus; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Glycogen Synthase Kinase 3 beta; Isoxazoles; Kidney Cortex; Lysophospholipids; Male; Mice, Inbred C57BL; Phosphoric Diester Hydrolases; Phosphorylation; Propionates; Receptors, Lysophosphatidic Acid; RNA Interference; Signal Transduction; Smad2 Protein; Smad3 Protein; Sterol Regulatory Element Binding Protein 1; Time Factors; Transfection; Transforming Growth Factor beta | 2017 |
Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.
Topics: Activins; Animals; Cell Differentiation; Chondrocytes; Chondrogenesis; Embryonic Stem Cells; Female; Humans; Induced Pluripotent Stem Cells; Inhibitory Concentration 50; Lysophospholipids; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Myositis Ossificans; Oligonucleotide Array Sequence Analysis; Phosphoric Diester Hydrolases; Point Mutation; Recombinant Proteins; Signal Transduction; TOR Serine-Threonine Kinases; Transforming Growth Factor beta | 2017 |
Platelets Promote Metastasis via Binding Tumor CD97 Leading to Bidirectional Signaling that Coordinates Transendothelial Migration.
Topics: Antigens, CD; Blood Platelets; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Dimerization; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Humans; Lysophospholipids; Platelet Activation; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; RNA Interference; RNA, Small Interfering; Signal Transduction; Tight Junctions; Transforming Growth Factor beta | 2018 |
Inhibition of ChREBP ubiquitination via the ROS/Akt-dependent downregulation of Smurf2 contributes to lysophosphatidic acid-induced fibrosis in renal mesangial cells.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Diabetic Nephropathies; Down-Regulation; Female; Fibronectins; Fibrosis; Lysophospholipids; Male; Mesangial Cells; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; TNF Receptor-Associated Factor 4; Transforming Growth Factor beta; Ubiquitin-Protein Ligases; Ubiquitination | 2022 |