lysophosphatidic acid has been researched along with pd 98059 in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (82.35) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Kim, DS; Kim, SE; Kwon, SB; Park, ES; Park, KC; Park, SH; Youn, SW | 1 |
| Adams, JW; Brunton, LL; Gustafsson, AB; Heller Brown, J; Hilal-Dandan, R; Means, CK; Morissette, MR | 1 |
| Gouni-Berthold, I; Hescheler, J; Sachinidis, A; Seewald, S | 1 |
| Deng, W; Johnson, LR; Makarova, N; Patel, TB; Poppleton, H; Shinozuka, Y; Tigyi, G; Wang, DA; Yasuda, S | 1 |
| Funfar, MR; Korpi, NL; McCoy, AC; Olmschenk, SM; Provost, JJ; Thronson, HL; Wallert, MA | 1 |
| Hatamochi, A; Sato, M; Shegogue, D; Trojanowska, M; Yamazaki, S | 1 |
| El Shewy, H; Gesty-Palmer, D; Kohout, TA; Luttrell, LM | 1 |
| Bae, YS; Im, DS; Jo, SH; Kim, MK; Kim, SD; Lee, HY; Park, KS; Shin, EH | 1 |
| Fishman, DA; Kang, S; Luo, R; Meng, Y; Smicun, Y | 1 |
| Bae, YS; Kim, SD; Lee, HY; Lee, SY; Shim, JW | 1 |
| Choi, WS; Han, JW; Jeong, KJ; Kang, JK; Kim, YK; Lee, HY; Lee, KB; Park, CG; Park, SY; Seo, JH | 1 |
| Adolfo García-Sáinz, J; Alcántara-Hernández, R | 1 |
| Niu, JP; Zhang, ZJ; Zhou, ZB | 1 |
| Bollinger, N; Joslin, EJ; Lauffenburger, DA; Opresko, LK; Shankaran, H; Wiley, HS | 1 |
| He, P; Lee, SJ; Yoo, BK; Yun, CC | 1 |
| Allen, LD; Dréau, D; Eddy, J; Nguyen, D; Swamydas, M | 1 |
17 other study(ies) available for lysophosphatidic acid and pd 98059
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Lysophosphatidic acid inhibits melanocyte proliferation via cell cycle arrest.
Topics: Animals; Cell Cycle; Cell Line, Transformed; Dose-Response Relationship, Drug; Flavonoids; Growth Inhibitors; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; MAP Kinase Signaling System; Melanocytes; Mice; Mitogen-Activated Protein Kinases; Peptides | 2003 |
Lysophosphatidic acid induces hypertrophy of neonatal cardiac myocytes via activation of Gi and Rho.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Blotting, Western; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Hydrolysis; Inhibitory Concentration 50; Luciferases; Lysophospholipids; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Myocytes, Cardiac; Pertussis Toxin; Phosphatidylinositols; Protein Biosynthesis; Protein Kinase C; Proteins; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; RNA, Messenger; Time Factors; Transfection; Type C Phospholipases | 2004 |
Regulation of mitogen-activated protein kinase cascades by low density lipoprotein and lysophosphatidic acid.
Topics: Animals; Aorta; Calcium Signaling; Cell Cycle Proteins; Cells, Cultured; Dual Specificity Phosphatase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Enzymologic; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Immediate-Early Proteins; Isoenzymes; Lipoproteins, LDL; Lysophospholipids; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Inbred WKY | 2004 |
Optimal lysophosphatidic acid-induced DNA synthesis and cell migration but not survival require intact autophosphorylation sites of the epidermal growth factor receptor.
Topics: Animals; Apoptosis; Cell Line; Cell Movement; Cell Survival; DNA; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Lysophospholipids; Mice; Pertussis Toxin; Phosphorylation; Receptor Protein-Tyrosine Kinases; Tumor Necrosis Factor-alpha | 2004 |
Two G protein-coupled receptors activate Na+/H+ exchanger isoform 1 in Chinese hamster lung fibroblasts through an ERK-dependent pathway.
Topics: Amides; Animals; Butadienes; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Lysophospholipids; MAP Kinase Kinase 1; Nitriles; Phenylephrine; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Pyridines; Receptors, Adrenergic, alpha; Receptors, G-Protein-Coupled; rho-Associated Kinases; Signal Transduction; Sodium-Hydrogen Exchangers; Transfection | 2005 |
Lysophosphatidic acid inhibits TGF-beta-mediated stimulation of type I collagen mRNA stability via an ERK-dependent pathway in dermal fibroblasts.
Topics: Blotting, Northern; Cells, Cultured; Collagen; Collagen Type I; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Humans; Immunoprecipitation; Luciferases; Lysophospholipids; Platelet-Derived Growth Factor; RNA; RNA, Messenger; Time Factors; Transfection; Transforming Growth Factor beta | 2004 |
beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts.
Topics: Animals; Arrestins; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Cells, Cultured; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Epitopes; ErbB Receptors; Fibroblasts; Flavonoids; Gene Expression Regulation; Humans; Lysophospholipids; Mice; Mice, Knockout; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Phosphorylation; Quinazolines; ras Proteins; RNA; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrphostins | 2005 |
Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chemotaxis; Enzyme Activation; Estrenes; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Lysophospholipids; Mice; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphodiesterase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidinones; Receptors, Lysophosphatidic Acid; Sphingosine | 2006 |
Selective induction of cyclooxygenase-2 plays a role in lysophosphatidic acid regulated Fas ligand cell surface presentation.
Topics: Animals; Antigen Presentation; Antigens, Surface; Apoptosis; Aspirin; Cell Line, Tumor; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fas Ligand Protein; Female; Flavonoids; Humans; Lymphocyte Activation; Lymphocytes; Lysophospholipids; Membrane Glycoproteins; Nitrobenzenes; Ovarian Neoplasms; Quinazolines; Signal Transduction; Sulfonamides; Tumor Necrosis Factors; Tyrphostins | 2006 |
Lysophosphatidylglycerol stimulates chemotactic migration and tube formation in human umbilical vein endothelial cells.
Topics: Cell Line; Cell Movement; Chemotaxis; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Immunoblotting; Isoxazoles; Lysophospholipids; Neovascularization, Physiologic; Pertussis Toxin; Propionates; Receptors, Lysophosphatidic Acid; Umbilical Veins | 2007 |
Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.
Topics: Butadienes; Cell Line, Tumor; Cell Movement; CSK Tyrosine-Protein Kinase; Cyclooxygenase 2; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Lysophospholipids; Nitriles; Ovarian Neoplasms; Pertussis Toxin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrimidines; Quinazolines; Receptors, Lysophosphatidic Acid; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; src-Family Kinases; Transcriptional Activation; Tyrphostins | 2008 |
Effect of inhibitors of mitogen-activated protein kinase kinase on alpha(1B)-adrenoceptor phosphorylation.
Topics: Androstadienes; Animals; Butadienes; Calcium Signaling; Cell Line; Cricetinae; Endothelin-1; Epidermal Growth Factor; Flavonoids; Genistein; Humans; Indoles; Lysophospholipids; Maleimides; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Norepinephrine; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Adrenergic, alpha-1; RNA, Small Interfering; Staurosporine; Tetradecanoylphorbol Acetate; Wortmannin | 2009 |
Receptor-mediated vascular smooth muscle migration induced by LPA involves p38 mitogen-activated protein kinase pathway activation.
Topics: Animals; Cell Movement; Cells, Cultured; Diphosphates; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glycerol; Imidazoles; Lysophospholipids; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid | 2009 |
Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context.
Topics: Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gefitinib; Gene Regulatory Networks; Hepatocyte Growth Factor; Humans; Imidazoles; Ligands; Lysophospholipids; Mammary Glands, Human; Phosphorylation; Pyridines; Quinazolines; Signal Transduction; Transcriptional Activation; Transforming Growth Factor alpha | 2010 |
Lysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cells.
Topics: Butadienes; Caco-2 Cells; Chromones; Enzyme Inhibitors; ErbB Receptors; Estrenes; Flavonoids; Focal Adhesion Kinase 2; Humans; Intestines; Lysophospholipids; Mitogen-Activated Protein Kinase Kinases; Morpholines; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C beta; Pyrrolidinones; Receptors, Lysophosphatidic Acid; rho-Associated Kinases; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2011 |
Progranulin stimulated by LPA promotes the migration of aggressive breast cancer cells.
Topics: Antibodies; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Flavonoids; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; MAP Kinase Signaling System; Neoplasm Invasiveness; Progranulins; RNA, Small Interfering; Transfection | 2011 |