lysophosphatidic acid has been researched along with organophosphonates in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aoki, J; Arai, H; Prestwich, GD; Tanaka, M; Xu, Y | 1 |
| Aoki, J; Arai, H; Hama, K; Mills, GB; Prestwich, GD; Qian, L; Shimizu, K; Takanezawa, Y; Umezu-Goto, M; Xu, Y; Yu, S | 1 |
| Gajewiak, J; Jiang, G; Prestwich, GD; Qian, L; Xu, Y | 1 |
| Becker, CJ; Cui, P; Lee, S; Lynch, KR; Macdonald, TL; McCalmont, WF; Tomsig, JL | 1 |
| Fujiwara, Y; Gajewiak, J; Jiang, G; Prestwich, GD; Tigyi, G; Tsukahara, R; Tsukahara, T; Xu, Y | 1 |
| Fujiwara, Y; Gajewiak, J; Lu, Y; Mills, GB; Murph, M; Prestwich, GD; Tigyi, G; Tsukahara, R; Tsukahara, T; Yu, S | 1 |
| Cui, P; Lynch, KR; Macdonald, TL; McCalmont, WF; Tomsig, JL | 1 |
| Bertrand, M; Beucher-Gaudin, M; Boutin, JA; Cordi, A; Desos, P; Ferry, G; Genton, A; Giganti, A; Lonchampt, M; Moulharat, N; Pradère, JP; Saulnier-Blache, JS; Try, A; Tucker, GC | 1 |
| Brindley, DN; Gaetano, CG; Lynch, KR; Macdonald, TL; Samadi, N; Tomsig, JL | 1 |
| Fells, JI; Fujiwara, Y; Gajewiak, J; Liu, J; Parrill, AL; Perygin, D; Prestwich, GD; Tigyi, G; Tsukahara, R; Xu, X; Zhang, H | 1 |
| Li, S; Wang, B; Xu, Y; Zhang, J | 1 |
| Balazs, L; Fells, J; Fujiwara, Y; Gotoh, M; Gupte, R; Kennel, S; Lee, S; Liu, J; Miller, DD; Murakami-Murofushi, K; Patil, R; Tigyi, GJ; Uchiyama, A; Wall, J; Yue, J | 1 |
| Blom, AW; Brown, J; Faul, CF; Knapp, JG; Mansell, JP | 1 |
| Aidinis, V; Bouros, D; Kaffe, E; Karameris, A; Mouratis, MA; Oikonomou, N; Prestwich, GD; Tzouvelekis, A; Valavanis, C; Vilaras, G | 1 |
| Antalis, C; Cai, Q; Del Priore, G; Hamed, AH; Schilder, JM; Stehman, FB; Xu, Y; Yan, L; Zhao, Z | 1 |
| Challa, P; Iyer, P; Lalane, R; Morris, C; Rao, PV; Vann, R | 1 |
| Katakai, T; Kinashi, T; Kondo, N; Ueda, Y | 1 |
| Blom, AW; Mansell, JP; Neary, G; Shiel, AI; Wheway, G | 1 |
2 review(s) available for lysophosphatidic acid and organophosphonates
| Article | Year |
|---|---|
New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors.
Topics: Enzyme Inhibitors; Fluorine; Humans; Hydroxides; Lysophospholipids; Molecular Structure; Organophosphonates | 2005 |
Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis.
Topics: Animals; Antineoplastic Agents; Humans; Lysophospholipids; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasms; Organophosphonates; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction; Xenograft Model Antitumor Assays | 2012 |
16 other study(ies) available for lysophosphatidic acid and organophosphonates
| Article | Year |
|---|---|
Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors.
Topics: Animals; Antineoplastic Agents; Calcium; Cell Line, Tumor; Cell Movement; Humans; Insecta; Intracellular Fluid; Lysophospholipids; Molecular Conformation; Organophosphonates; Protein Isoforms; Receptors, Lysophosphatidic Acid; Structure-Activity Relationship; Substrate Specificity | 2004 |
Structure-activity relationships of fluorinated lysophosphatidic acid analogues.
Topics: Animals; Calcium; Cell Line; Cell Line, Tumor; Chemotaxis; Fluorine; Humans; Insecta; Ligands; Lysophospholipids; Mitogen-Activated Protein Kinase Kinases; Organophosphonates; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Lysophosphatidic Acid; Stereoisomerism; Structure-Activity Relationship | 2005 |
Synthesis and biological evaluation of phosphonate derivatives as autotaxin (ATX) inhibitors.
Topics: Hydrolysis; Indicators and Reagents; Lysophospholipids; Multienzyme Complexes; Organophosphonates; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Stereoisomerism; Structure-Activity Relationship | 2007 |
Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Lysophospholipids; Organophosphonates | 2007 |
Alkoxymethylenephosphonate analogues of (Lyso) phosphatidic acid stimulate signaling networks coupled to the LPA2 receptor.
Topics: Cell Line, Tumor; Humans; Lysophospholipids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Neoplasms; Organophosphonates; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2007 |
alpha- and beta-substituted phosphonate analogs of LPA as autotaxin inhibitors.
Topics: Lysophospholipids; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphonates; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrophosphatases; Structure-Activity Relationship | 2008 |
S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool.
Topics: 3T3 Cells; Anilides; Animals; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Lysophospholipids; Mice; Multienzyme Complexes; Organophosphonates; Phosphatidylcholines; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases | 2008 |
Inhibition of autotaxin production or activity blocks lysophosphatidylcholine-induced migration of human breast cancer and melanoma cells.
Topics: Anilides; Blotting, Western; Breast Neoplasms; Catalysis; Cell Line; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Humans; Kinetics; Lysophosphatidylcholines; Lysophospholipids; Melanoma; Multienzyme Complexes; Organophosphates; Organophosphonates; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyridines; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Transfection | 2009 |
Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Humans; Lysophospholipids; Multienzyme Complexes; Organophosphonates; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Receptors, Lysophosphatidic Acid | 2009 |
Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis.
Topics: Acetylation; Anilides; Apoptosis; Cell Line, Tumor; Cytoprotection; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Lysophospholipids; Multienzyme Complexes; Organophosphonates; Phosphodiesterase I; Phosphoric Diester Hydrolases; Promoter Regions, Genetic; Pyrophosphatases; Receptors, Lysophosphatidic Acid; RNA, Messenger; Signal Transduction; Up-Regulation | 2011 |
Lysophosphatidic acid-functionalised titanium as a superior surface for supporting human osteoblast (MG63) maturation.
Topics: Alkaline Phosphatase; Bone Density Conservation Agents; Calcitriol; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Lysophospholipids; Microscopy, Electron, Scanning; Molecular Structure; Organophosphonates; Osteoblasts; Osteogenesis; Photoelectron Spectroscopy; Surface Properties; Time Factors; Titanium | 2012 |
Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis.
Topics: Adult; Aged; Anilides; Animals; Bronchoalveolar Lavage Fluid; Female; Gene Expression; Gene Knockout Techniques; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lysophospholipids; Macrophages, Alveolar; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Organophosphonates; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Respiratory Mucosa | 2012 |
Elevated and secreted phospholipase A₂ activities as new potential therapeutic targets in human epithelial ovarian cancer.
Topics: Animals; Arachidonic Acids; Ascites; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Female; Humans; Lysophospholipids; Mice; Neoplasm Transplantation; Neoplasms, Glandular and Epithelial; Organophosphonates; Ovarian Neoplasms; Phospholipases A2, Secretory; Phosphoric Diester Hydrolases; Transplantation, Heterologous | 2012 |
Autotaxin-lysophosphatidic acid axis is a novel molecular target for lowering intraocular pressure.
Topics: Anilides; Animals; Aqueous Humor; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lysophospholipids; Models, Animal; Organophosphonates; Phosphoric Diester Hydrolases; Proteomics; Rabbits; RNA, Small Interfering; Trabecular Meshwork | 2012 |
Autotaxin produced by stromal cells promotes LFA-1-independent and Rho-dependent interstitial T cell motility in the lymph node paracortex.
Topics: Anilides; Animals; Cell Movement; Cells, Cultured; Chemokine CCL21; Female; Isoxazoles; Lymph Nodes; Lymphocyte Function-Associated Antigen-1; Lysophospholipids; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence, Multiphoton; Myosin Type II; Oligonucleotide Array Sequence Analysis; Organophosphonates; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Propionates; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Stromal Cells; T-Lymphocytes; Transcriptome | 2014 |
Development and biological evaluation of fluorophosphonate-modified hydroxyapatite for orthopaedic applications.
Topics: Alkaline Phosphatase; Bone Regeneration; Cell Differentiation; Cell Line, Tumor; Coated Materials, Biocompatible; Durapatite; Fluorides; Humans; Lysophospholipids; Materials Testing; Organophosphonates; Osseointegration; Osteoblasts; Osteogenesis; Prostheses and Implants; Sequence Analysis, RNA; Stress, Mechanical; Surface Properties; Titanium | 2018 |