lysophosphatidic acid has been researched along with interleukin-8 in 32 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 20 (62.50) | 29.6817 |
2010's | 10 (31.25) | 24.3611 |
2020's | 2 (6.25) | 2.80 |
Authors | Studies |
---|---|
Aggarwal, BB; Bast, RC; Claret, FX; Fang, X; Hu, SX; LaPushin, R; Liu, S; Lu, Y; Mills, GB; Xu, HJ; Yu, S | 1 |
Cummings, R; Garcia, JG; He, D; Jacoby, D; Natarajan, V; Ohba, M; Saatian, B; Spannhake, EW; Watkins, T; Zhao, Y | 1 |
Brindley, DN; Cummings, R; He, D; Morris, A; Natarajan, V; Saatian, B; Spannhake, EW; Usatyuk, PV; Watkins, T; Zhao, Y | 1 |
Fishman, DA; Navari, J; So, J; Wang, FQ | 1 |
Bordet, JC; Boucharaba, A; Clézardin, P; Grès, S; Guglielmi, J; Peyruchaud, O; Saulnier-Blache, JS; Serre, CM | 1 |
Castleberry, A; Hall, RA; Rusovici, R; Shim, H; Sun, H; Wang, D; Yun, CC | 1 |
Georas, SN; He, D; Natarajan, V; Saatian, B; Spannhake, EW; Watkins, T; Zhao, Y | 1 |
Kitayama, J; Mori, K; Nagawa, H; Shida, D; Watanabe, T; Yamashita, H | 1 |
He, D; Natarajan, V; Pyne, NJ; Saatian, B; Spannhake, EW; Watkins, T; Zhao, Y | 1 |
Chen, CN; Chen, JH; Lee, H; Lin, CI | 1 |
Chiu, TT; Leung, WY; Moyer, MP; Rozengurt, E; Strieter, RM | 1 |
Lin, PC; Lin, X; Morris, SW; Wang, D; Wen, R; Xue, L; You, Y; Zeng, H | 1 |
Aki, Y; Kondo, A; Nakamura, H; Togari, A | 1 |
Chang, KJ; Chen, CN; Hsieh, FJ; Lee, H; Lin, CI; Lin, PW | 1 |
Chen, SU; Chou, CH; Ho, CH; Lee, H; Lin, CW; Yang, YS | 1 |
Chang, CY; Chang, DY; Chao, KH; Chen, SU; Chou, CH; Lee, H; Lin, CW; Yang, YS | 1 |
Gustin, C; Raes, M; Van Steenbrugge, M | 1 |
Alvarez, SE; Fang, X; Kordula, T; Lépine, S; Milstien, S; Shida, D; Spiegel, S; Takabe, K | 1 |
Berdyshev, EV; Kalari, S; Natarajan, V; Spannhake, EW; Zhao, Y | 1 |
Cho, DY; Jeong, KJ; Kang, JK; Kim, YK; Lee, HY; Oh, WJ; Park, CG; Seo, JH; Sohn, JS; Sul, HJ | 1 |
Chao, KH; Chen, SU; Chou, CH; Lee, H; Lin, CW; Lu, HF; Yang, YS | 1 |
Dang, D; Dent, P; Fang, X; Greenbaum, S; Lee, Z; Mukherjee, A; Oyesanya, RA; Wu, J | 1 |
Boucharaba, A; Clézardin, P; Guillet, B; Hneino, M; Menaa, F; Oliver, P; Peyruchaud, O; Philippe, C; van Wijnen, AJ | 1 |
Rajagopalan, LE; Shimada, H | 1 |
Berdyshev, E; Chun, J; He, D; Natarajan, V; Su, Y; Zhao, J; Zhao, Y | 1 |
Chung, WY; Hwang, YS; Lee, SK; Park, KK | 1 |
Bar-Eli, M; Calderone, TL; Davies, MA; Gershenwald, JE; Mills, GB; Mu, H; Prieto, VG; Wang, H | 1 |
Bourgoin, SG; Fernandes, MJ; Hui, W; Poubelle, PE; Zhao, C | 1 |
Chang, PJ; Chang, WM; Chen, KH; Chuang, YW; Hong, CZ; Hsu, HC | 1 |
Alnouti, Y; Bathena, SP; Cerutis, DR; Headen, KV; McVaney, TP; Miyamoto, T; Nunn, ME; Ogunleye, AO; Weston, MD | 1 |
Fang, X; He, T; Ma, Y; Mukherjee, A; Wang, W; Wang, XY; Wu, J | 1 |
Hirata, N; Kanda, Y; Nishida, M; Ono, A; Yamada, S; Yanagida, S; Yasuhiko, Y | 1 |
32 other study(ies) available for lysophosphatidic acid and interleukin-8
Article | Year |
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Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells.
Topics: Cell Line, Tumor; Female; Humans; Interleukin-6; Interleukin-8; Lysophospholipids; Ovarian Neoplasms; Promoter Regions, Genetic; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Transcriptional Activation | 2004 |
Protein kinase Cdelta mediates lysophosphatidic acid-induced NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells.
Topics: Acetophenones; Active Transport, Cell Nucleus; Animals; Benzopyrans; Blotting, Western; Bronchoalveolar Lavage; Cell Nucleus; Cells, Cultured; Chemokine CXCL2; Chemokines; Cytokines; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Inflammation; Interleukin-8; Luciferases; Lysophospholipids; Macrophages; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; NF-kappa B; Oligonucleotide Array Sequence Analysis; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Receptor, Platelet-Derived Growth Factor beta; RNA; Signal Transduction; Time Factors; Transcriptional Activation; Transfection | 2004 |
Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells.
Topics: Adenoviridae; Arginine; Bronchi; Calcium; Cell Extracts; Cells, Cultured; Epithelial Cells; Humans; Interleukin-8; Lung Transplantation; Lysine; Lysophospholipids; Mutation, Missense; NF-kappa B; Phosphatidate Phosphatase; Receptors, Lysophosphatidic Acid; Tissue Donors | 2005 |
Lysophosphatidic acid enhances epithelial ovarian carcinoma invasion through the increased expression of interleukin-8.
Topics: Cell Line, Tumor; Cell Movement; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interleukin-8; Lysophospholipids; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Ovarian Neoplasms | 2004 |
Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer.
Topics: Animals; Blood Platelets; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cricetinae; Culture Media; Cytokines; Disease Progression; Dose-Response Relationship, Drug; Doxycycline; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Interleukin-6; Interleukin-8; Ki-67 Antigen; Lysophospholipids; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogens; Models, Biological; Neoplasm Metastasis; Osteoclasts; Osteolysis; Phospholipase D; Platelet Activation; Platelet Aggregation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Time Factors; Transfection | 2004 |
LPA2 receptor mediates mitogenic signals in human colon cancer cells.
Topics: Caco-2 Cells; Colonic Neoplasms; Cytoskeletal Proteins; Drug Interactions; Enzyme Activation; Humans; Interleukin-8; Intestinal Mucosa; Lysophospholipids; Mitogen-Activated Protein Kinase Kinases; Mitosis; Phosphoproteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Lysophosphatidic Acid; RNA, Small Interfering; Signal Transduction; Sodium-Hydrogen Exchangers | 2005 |
Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells.
Topics: Bronchi; Epithelial Cells; Gene Expression Regulation; Humans; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Transport; Respiratory Mucosa; Transcription Factor AP-1; Transcription, Genetic | 2006 |
Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.
Topics: Cell Line, Tumor; Chemotaxis; Colonic Neoplasms; Dipeptides; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Humans; Interleukin-8; Lysophospholipids; Phosphorylation; Phosphotyrosine; Protease Inhibitors; Quinazolines; Transcriptional Activation; Tyrphostins | 2006 |
Regulation of lysophosphatidic acid-induced epidermal growth factor receptor transactivation and interleukin-8 secretion in human bronchial epithelial cells by protein kinase Cdelta, Lyn kinase, and matrix metalloproteinases.
Topics: Bronchi; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Lysophospholipids; Matrix Metalloproteinases; Protein Kinase C-delta; src-Family Kinases; Transcriptional Activation | 2006 |
Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism.
Topics: Carrier Proteins; Chemokine CCL2; Chemotaxis; Endothelial Cells; Humans; Interleukin-1; Interleukin-8; Lysophospholipids; Pertussis Toxin; Proline; RNA, Messenger; Sphingosine; Thiocarbamates; Time Factors; Umbilical Veins; Up-Regulation; Vesicular Transport Proteins | 2006 |
Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB.
Topics: Cell Line; Colon; Enzyme Activation; Epithelial Cells; Humans; Indoles; Interleukin-8; Intestinal Mucosa; Lysophospholipids; NF-kappa B; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase D2; Protein Kinases | 2007 |
Bcl10 plays a critical role in NF-kappaB activation induced by G protein-coupled receptors.
Topics: Adaptor Proteins, Signal Transducing; Animals; B-Cell CLL-Lymphoma 10 Protein; Cells, Cultured; Humans; Interleukin-8; Lysophospholipids; Mice; NF-kappa B; Phosphatidylinositol 3-Kinases; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Necrosis Factor-alpha | 2007 |
Lysophosphatidic acid-stimulated interleukin-6 and -8 synthesis through LPA1 receptors on human osteoblasts.
Topics: Boron Compounds; Calcium; Dose-Response Relationship, Drug; Estrenes; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate Receptors; Interleukin-6; Interleukin-8; Isoxazoles; Lysophospholipids; Osteoblasts; Propionates; Pyrrolidinones; Receptors, Lysophosphatidic Acid; RNA, Messenger; Signal Transduction; Stimulation, Chemical; Tumor Cells, Cultured; Type C Phospholipases | 2008 |
Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3.
Topics: Cell Adhesion; Cells, Cultured; Chemokine CCL2; Endothelial Cells; Gene Expression Regulation; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-8; Lysophospholipids; Peptide Fragments; Receptors, Lysophosphatidic Acid; RNA, Small Interfering | 2007 |
Lysophosphatidic acid up-regulates expression of interleukin-8 and -6 in granulosa-lutein cells through its receptors and nuclear factor-kappaB dependent pathways: implications for angiogenesis of corpus luteum and ovarian hyperstimulation syndrome.
Topics: Cells, Cultured; Corpus Luteum; Female; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Luteal Cells; Lysophospholipids; Neovascularization, Physiologic; NF-kappa B; Ovarian Hyperstimulation Syndrome; Receptors, Lysophosphatidic Acid; Signal Transduction; Up-Regulation | 2008 |
Lysophosphatidic acid mediates interleukin-8 expression in human endometrial stromal cells through its receptor and nuclear factor-kappaB-dependent pathway: a possible role in angiogenesis of endometrium and placenta.
Topics: Adult; Cells, Cultured; Endometrium; Female; Gene Expression Regulation; Humans; Interleukin-8; Lysophospholipids; Models, Biological; Neovascularization, Physiologic; NF-kappa B; Placenta; Pregnancy; Receptors, Lysophosphatidic Acid; RNA, Messenger; Signal Transduction; Stromal Cells | 2008 |
LPA modulates monocyte migration directly and via LPA-stimulated endothelial cells.
Topics: Cell Line; Cell Movement; Chemokine CCL2; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation; Humans; Interleukin-8; Lysophospholipids; Monocytes; PPAR gamma; Receptors, Lysophosphatidic Acid | 2008 |
Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion.
Topics: Blotting, Western; Breast Neoplasms; Cell Movement; Cell Proliferation; Chemotaxis; Colonic Neoplasms; ErbB Receptors; Humans; Interleukin-6; Interleukin-8; Lysophospholipids; Neoplasm Invasiveness; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Stomach Neoplasms; Transcriptional Activation; Tumor Cells, Cultured; Up-Regulation; Urokinase-Type Plasminogen Activator | 2008 |
Role of acylglycerol kinase in LPA-induced IL-8 secretion and transactivation of epidermal growth factor-receptor in human bronchial epithelial cells.
Topics: Base Sequence; Bronchi; Cells, Cultured; DNA Primers; Epithelial Cells; ErbB Receptors; Humans; Interleukin-8; Lysophospholipids; MAP Kinase Signaling System; NF-kappa B; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; RNA, Messenger; RNA, Small Interfering; Subcellular Fractions; Transcriptional Activation; Transfection | 2009 |
Lysophosphatidic acid induces STAT3 phosphorylation and ovarian cancer cell motility: their inhibition by curcumin.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Cell Survival; Curcumin; Dose-Response Relationship, Drug; Female; Humans; Interleukin-6; Interleukin-8; Janus Kinases; Lysophospholipids; Neoplasm Invasiveness; Ovarian Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction; STAT3 Transcription Factor; Transfection; Tyrphostins | 2010 |
Lysophosphatidic acid up-regulates expression of growth-regulated oncogene-alpha, interleukin-8, and monocyte chemoattractant protein-1 in human first-trimester trophoblasts: possible roles in angiogenesis and immune regulation.
Topics: Cells, Cultured; Chemokine CCL2; Chemokine CXCL1; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Developmental; Humans; Immunity, Innate; Interleukin-8; Lysophospholipids; Neovascularization, Physiologic; Pregnancy; Pregnancy Trimester, First; Receptors, Lysophosphatidic Acid; Signal Transduction; Trophoblasts; Up-Regulation | 2010 |
Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Female; GTP-Binding Proteins; Hepatocyte Growth Factor; Humans; Interleukin-8; Lysophospholipids; Neoplasm Invasiveness; NF-kappa B; Phosphotyrosine; Transcription Factor AP-1 | 2010 |
Bioactive lipids lysophosphatidic acid and sphingosine 1-phosphate mediate breast cancer cell biological functions through distinct mechanisms.
Topics: Bone Marrow Cells; Breast Neoplasms; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Chemokine CXCL1; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Lysophospholipids; Neovascularization, Physiologic; Osteoclasts; Phosphatidylinositol 3-Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Umbilical Veins; Vascular Endothelial Growth Factor A | 2009 |
Rho-kinase mediates lysophosphatidic acid-induced IL-8 and MCP-1 production via p38 and JNK pathways in human endothelial cells.
Topics: Blotting, Western; Cells, Cultured; Chemokine CCL2; Endothelial Cells; Humans; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; p38 Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Signal Transduction; Transcription Factor RelA | 2010 |
Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs.
Topics: Animals; Bronchi; Bronchoalveolar Lavage Fluid; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; Inflammation; Interleukin-6; Interleukin-8; Isoxazoles; Lipopolysaccharide Receptors; Lipopolysaccharides; Lysophospholipids; Male; Membrane Microdomains; Mice; Mice, Knockout; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Propionates; Pulmonary Alveoli; Receptor Cross-Talk; Receptors, Lysophosphatidic Acid; Signal Transduction | 2011 |
Secretion of IL-6 and IL-8 from lysophosphatidic acid-stimulated oral squamous cell carcinoma promotes osteoclastogenesis and bone resorption.
Topics: Animals; Biological Assay; Blotting, Western; Bone Neoplasms; Bone Resorption; Carcinoma, Squamous Cell; Humans; Interleukin-6; Interleukin-8; Lysophospholipids; Mice; Mouth Neoplasms; Osteoclasts; RANK Ligand; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Lysophosphatidic acid induces lymphangiogenesis and IL-8 production in vitro in human lymphatic endothelial cells.
Topics: Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Interleukin-8; Lymphangiogenesis; Lymphatic Metastasis; Lymphatic Vessels; Lysophospholipids; Melanoma; NF-kappa B; Receptors, Lysophosphatidic Acid; RNA, Small Interfering; Sentinel Lymph Node Biopsy; Signal Transduction; Up-Regulation | 2012 |
Lysophosphatidic acid-induced IL-8 secretion involves MSK1 and MSK2 mediated activation of CREB1 in human fibroblast-like synoviocytes.
Topics: Arthritis, Rheumatoid; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chemokine CCL2; Cyclic AMP Response Element-Binding Protein; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Interleukin-8; Lysophospholipids; Oxadiazoles; Phosphorylation; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Serine; Synovial Membrane | 2014 |
Lysophosphatidic acid enhanced the angiogenic capability of human chondrocytes by regulating Gi/NF-kB-dependent angiogenic factor expression.
Topics: Angiogenesis Inducing Agents; Cartilage, Articular; Cell Line; Chemokine CCL2; Chondrocytes; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Insulin-Like Growth Factor Binding Protein 1; Interleukin-8; Lysophospholipids; Matrix Metalloproteinase 9; Neovascularization, Physiologic; NF-kappa B; Ribonuclease, Pancreatic; RNA, Messenger; Signal Transduction; Vascular Endothelial Growth Factor A | 2014 |
A Major Human Oral Lysophosphatidic Acid Species, LPA 18:1, Regulates Novel Genes in Human Gingival Fibroblasts.
Topics: Adult; Cells, Cultured; Female; Fibroblasts; Gene Expression Regulation; Gingiva; Gingival Crevicular Fluid; Humans; Inflammation; Inflammation Mediators; Interleukin-11; Interleukin-6; Interleukin-8; Lysophospholipids; Male; Phosphoric Diester Hydrolases; Saliva; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Transcription, Genetic | 2015 |
Lysophosphatidic acid induces tumor necrosis factor-alpha to regulate a pro-inflammatory cytokine network in ovarian cancer.
Topics: ADAM17 Protein; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; Lysophospholipids; Ovarian Neoplasms; Tumor Necrosis Factor-alpha | 2020 |
Lysophosphatidic Acid Promotes the Expansion of Cancer Stem Cells via TRPC3 Channels in Triple-Negative Breast Cancer.
Topics: Breast; Calcium; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Lysophospholipids; Neoplastic Stem Cells; Receptors, Lysophosphatidic Acid; Signal Transduction; Sphingosine; Triple Negative Breast Neoplasms; TRPC Cation Channels | 2022 |