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lysophosphatidic acid and epidermal growth factor

lysophosphatidic acid has been researched along with epidermal growth factor in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.22)18.2507
2000's31 (68.89)29.6817
2010's12 (26.67)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Albert, I; Cook, SJ; McCormick, F; Rubinfeld, B1
Hynes, AC; Kane, MT; Sreenan, JM1
Brunswig-Spickenheier, B; Budnik, LT; Mukhopadhyay, AK1
Ahmed, I; Drezner, MK; Gesty-Palmer, D; Luttrell, LM1
Mattingly, RR; Menard, RE1
Dooley, CT; Dore, TM; Hanson, GT; Jackson, WC; Remington, SJ; Tsien, RY1
Armant, DR; Liu, Z1
Anderson, GD; Ilies, M; Izban, MG; Jeng, YJ; Panova, NI; Soloff, MS; Soloff, SL; Velagaleti, GV; Wood, TG1
Hasuwa, H; Hirata, M; Kageyama, T; Kai, M; Kanoh, H; Mekada, E; Miyamoto, S; Mizushima, H; Nakano, H; Sonoda, K; Tanaka, Y; Yagi, H; Yamazaki, A1
Gschwind, A; Marg, B; Schäfer, B; Ullrich, A1
Fang, X; Hasegawa, Y; Lapushin, R; Liu, S; Mills, GB; Woodgett, JR; Xu, HJ; Yu, S1
Mekada, E; Miyamoto, S1
English, D; Hayes, RL; Ignatova, TN; Kukekov, VG; Svetlov, SI; Wang, KK1
Miyamoto, S; Tanaka, Y; Yagi, H1
Baukal, AJ; Catt, KJ; Shah, BH; Shah, FB1
Braun, AH; Coffey, RJ1
Jovanovski, AP; Mattingly, RR; Menard, RE1
El Shewy, H; Gesty-Palmer, D; Kohout, TA; Luttrell, LM1
Milstien, S; Spiegel, S1
Imajoh-Ohmi, S; Karatsu, T; Kasama, T; Nogawa, H; Noguchi, Y; Okamoto, A1
Adachi, S; Iwamoto, R; Mekada, E; Mizushima, H; Ohishi, M; Wang, X1
Crema, VO; Hamassaki, DE; Santos, MF1
He, D; Natarajan, V; Pyne, NJ; Saatian, B; Spannhake, EW; Watkins, T; Zhao, Y1
Jiang, X; Rozengurt, E; Sinnett-Smith, J1
Xu, KP; Yin, J; Yu, FS1
Barbour, SE; Chen, J; Fang, X; Hu, W; Lee, Z; Murthy, KS; Oyesanya, R; Song, Y; Wilkins, P; Wu, J1
Kassel, KM; Lanik, AD; Parker, SM; Schulte, NA; Toews, ML1
Kerkhoven, R; Moolenaar, WH; Stortelers, C1
Bisel, B; Miron-Mendoza, M; Nakamura, N; Seemann, J; Tang, D; Wang, Y; Wei, JH; Xiang, Y; Yoshimura, S1
Im, DS; Kimura, T; Komachi, M; Kurose, H; Kuwabara, A; Malchinkhuu, E; Mogi, C; Ohta, H; Okajima, F; Sato, K; Takeyoshi, I; Tobo, M; Tomura, H; Yamada, T1
Adolfo García-Sáinz, J; Alcántara-Hernández, R1
Bessette, DC; Chen, SC; Khanna, RS; Pallen, CJ; Samayawardhena, LA1
Meier, KE; Snider, AJ; Xie, Y; Zhang, Z1
Dang, D; Dent, P; Fang, X; Greenbaum, S; Lee, Z; Mukherjee, A; Oyesanya, RA; Wu, J1
Holmström, TE; Iakovleva, I; Mattsson, CL; Nedergaard, J; Petrovic, N; Wang, Y1
Hikita, S; Kuroki, M; Miyamoto, S; Tsujioka, H; Ueda, T; Yotsumoto, F1
Altman, MK; Eneh, JO; Jia, W; Murph, MM; Ratnaparkhe, S1
Herrera, M; Losert, W; Parent, CA; Sato, M; Shou, K; Stuelten, CH; Vedham, V; Weiger, MC1
Cagnol, S; Carrier, JC; Leblanc, C; Paquin, MC; Rivard, N1
Chen, M; Harrison, SM; Knifley, T; O'Connor, KL1
Kera, H; Nogawa, H; Yuki, S1
Hopkins, MM; Liu, Z; Meier, KE1
Faraji, F; Gilliard, C; Hunter, K; Kelly, K; Ku, KP; Lake, R; Lang, J; Martin, P; Niles, D; Rodems, T; Sowalsky, AG; Sperger, J; Tillman, H; Ward, Y; Yin, J1
Imada, S; Konno, T; Kotani, T; Matozaki, T; Murata, Y; Nishigaito, Y; Saito, Y; Sawada, N; Setiawan, J1
Chian, RC; Wang, L; Wu, J; Xie, Q; Xing, Y; Zhou, J1

Reviews

4 review(s) available for lysophosphatidic acid and epidermal growth factor

ArticleYear
[Biological behavior of ovarian cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 10

    Topics: Ascitic Fluid; Calcium; Cell Division; Drug Design; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Lysophospholipids; Ovarian Neoplasms; Signal Transduction

2004
[HB-EGF is a promising target molecule for ovarian cancer].
    Fukuoka igaku zasshi = Hukuoka acta medica, 2004, Volume: 95, Issue:11

    Topics: Animals; Antineoplastic Agents; Bacterial Proteins; Cell Division; Drug Design; Epidermal Growth Factor; ErbB Receptors; Female; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Ligands; Lysophospholipids; Ovarian Neoplasms; Signal Transduction

2004
Critical role of acylglycerol kinase in epidermal growth factor-induced mitogenesis of prostate cancer cells.
    Biochemical Society transactions, 2005, Volume: 33, Issue:Pt 6

    Topics: Cell Proliferation; Cell Survival; Epidermal Growth Factor; Humans; Lysophospholipids; Male; Phosphatidic Acids; Phosphotransferases (Alcohol Group Acceptor); Prostatic Neoplasms; Receptors, G-Protein-Coupled; Signal Transduction

2005
Targeting the heparin-binding epidermal growth factor-like growth factor in ovarian cancer therapy.
    Current opinion in obstetrics & gynecology, 2011, Volume: 23, Issue:1

    Topics: Antineoplastic Agents; Bacterial Proteins; Cell Proliferation; Clinical Trials, Phase I as Topic; Epidermal Growth Factor; Female; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Ovarian Neoplasms; Protein Serine-Threonine Kinases; Signal Transduction

2011

Other Studies

41 other study(ies) available for lysophosphatidic acid and epidermal growth factor

ArticleYear
RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts.
    The EMBO journal, 1993, Volume: 12, Issue:9

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Genes, ras; GTP-Binding Proteins; Kinetics; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Molecular Sequence Data; Peptides; Proto-Oncogene Proteins; rap GTP-Binding Proteins; Rats; Recombinant Proteins; Signal Transduction

1993
The phosphatidylinositol signalling system in elongating bovine blastocysts; formation of phosphoinositides, inositol phosphates and stimulation by growth factors.
    Reproduction, fertility, and development, 2002, Volume: 14, Issue:7-8

    Topics: Animals; Blastocyst; Cattle; Epidermal Growth Factor; Growth Substances; Inositol; Inositol Phosphates; Lysophospholipids; Phosphatidylinositols; Platelet Activating Factor; Signal Transduction; Sodium; Tritium; Type C Phospholipases

2002
Lysophosphatidic acid signals through mitogen-activated protein kinase-extracellular signal regulated kinase in ovarian theca cells expressing the LPA1/edg2-receptor: involvement of a nonclassical pathway?
    Molecular endocrinology (Baltimore, Md.), 2003, Volume: 17, Issue:8

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cattle; Cell Membrane; Cell Nucleus; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Female; Humans; Lysophospholipids; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Protein Transport; ras Proteins; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Theca Cells

2003
Transactivation of the epidermal growth factor receptor mediates parathyroid hormone and prostaglandin F2 alpha-stimulated mitogen-activated protein kinase activation in cultured transgenic murine osteoblasts.
    Molecular endocrinology (Baltimore, Md.), 2003, Volume: 17, Issue:8

    Topics: Animals; Cell Differentiation; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Lysophospholipids; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoblasts; Parathyroid Hormone; Phosphorylation; Protein Kinase C; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Receptors, Prostaglandin; Signal Transduction; Transcriptional Activation; Tyrphostins

2003
Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinase-dependent pathways.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: Androstadienes; Animals; Carbachol; cdc42 GTP-Binding Protein; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Epidermal Growth Factor; ErbB Receptors; Humans; Indoles; Kinetics; Lysophospholipids; Maleimides; Mice; Models, Biological; Myelin Basic Protein; NIH 3T3 Cells; p21-Activated Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Quinazolines; rac GTP-Binding Proteins; ras Proteins; Receptor, Muscarinic M2; Receptors, Cell Surface; rho GTP-Binding Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tyrphostins; Wortmannin

2003
Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Cloning, Molecular; Dose-Response Relationship, Drug; Epidermal Growth Factor; Flow Cytometry; Glutathione; Glutathione Disulfide; Green Fluorescent Proteins; HeLa Cells; HL-60 Cells; Humans; Hydrogen Peroxide; Hypoxia; Luminescent Proteins; Lysine; Lysophospholipids; Magnetic Resonance Spectroscopy; Mutation; Oxidants; Oxidation-Reduction; Oxygen; Spectrometry, Fluorescence; Superoxides; Time Factors; Xanthine Oxidase

2004
Lysophosphatidic acid regulates murine blastocyst development by transactivation of receptors for heparin-binding EGF-like growth factor.
    Experimental cell research, 2004, Jun-10, Volume: 296, Issue:2

    Topics: Animals; Autocrine Communication; Blastocyst; Calcium; Cell Differentiation; Cells, Cultured; Embryo Implantation; Embryo, Mammalian; Epidermal Growth Factor; ErbB Receptors; Female; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Mice; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; RNA, Messenger; Transcriptional Activation; Trophoblasts

2004
Immortalization and characterization of human myometrial cells from term-pregnant patients using a telomerase expression vector.
    Molecular human reproduction, 2004, Volume: 10, Issue:9

    Topics: Cell Line; DNA-Binding Proteins; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Profiling; Genetic Vectors; Humans; I-kappa B Proteins; Interleukin-1; Karyotyping; Lysophospholipids; Myometrium; Myosin Light Chains; NF-KappaB Inhibitor alpha; Oligonucleotide Array Sequence Analysis; Oxytocin; Pregnancy; Signal Transduction; Telomerase

2004
Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy.
    Cancer research, 2004, Aug-15, Volume: 64, Issue:16

    Topics: Animals; Bacterial Proteins; Cell Line, Tumor; Epidermal Growth Factor; ErbB Receptors; Extracellular Fluid; Female; Gene Expression; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Mice; Ovarian Neoplasms; Receptors, Cell Surface; Transcriptional Activation; Transfection

2004
Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival.
    The Journal of biological chemistry, 2004, Nov-12, Volume: 279, Issue:46

    Topics: ADAM Proteins; ADAM17 Protein; Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Humans; Kidney Neoplasms; Ligands; Lysophospholipids; Metalloendopeptidases; Rats; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction; Transcriptional Activation; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms

2004
Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase.
    The Journal of biological chemistry, 2004, Dec-03, Volume: 279, Issue:49

    Topics: 3T3 Cells; Animals; Apoptosis; Blotting, Western; Cells, Cultured; Cytoplasm; DNA Mutational Analysis; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Genetic Vectors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Growth Substances; Homozygote; JNK Mitogen-Activated Protein Kinases; Ligands; Lithium Chloride; Lysophospholipids; Mice; Mitogen-Activated Protein Kinase 3; Mutation; Phosphorylation; Propidium; Protein Structure, Tertiary; Retroviridae; Signal Transduction; Sphingosine; Thymidine; Time Factors; Ultraviolet Rays

2004
Lysophosphatidic acid induces clonal generation of mouse neurospheres via proliferation of Sca-1- and AC133-positive neural progenitors.
    Stem cells and development, 2004, Volume: 13, Issue:6

    Topics: AC133 Antigen; Animals; Antigens, CD; Astrocytes; Ataxin-1; Ataxins; Brain; Cell Differentiation; Cell Lineage; Cell Proliferation; Cells, Cultured; Culture Media, Serum-Free; Diphosphates; Epidermal Growth Factor; Fibroblast Growth Factor 2; Glial Fibrillary Acidic Protein; Glycerol; Glycoproteins; Immunohistochemistry; Lysophospholipids; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Oligodendroglia; Peptides; Prosencephalon; Receptors, Lysophosphatidic Acid; Stem Cells

2004
Mechanisms of extracellularly regulated kinases 1/2 activation in adrenal glomerulosa cells by lysophosphatidic acid and epidermal growth factor.
    Molecular endocrinology (Baltimore, Md.), 2005, Volume: 19, Issue:10

    Topics: Animals; Cattle; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Heparin-binding EGF-like Growth Factor; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Matrix Metalloproteinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Transcriptional Activation; Zona Glomerulosa

2005
Lysophosphatidic acid, a disintegrin and metalloprotease-17 and heparin-binding epidermal growth factor-like growth factor in ovarian cancer: the first word, not the last.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Jul-01, Volume: 11, Issue:13

    Topics: ADAM Proteins; ADAM17 Protein; Antineoplastic Agents; Epidermal Growth Factor; Female; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Models, Biological; Ovarian Neoplasms; Signal Transduction

2005
Active p21-activated kinase 1 rescues MCF10A breast epithelial cells from undergoing anoikis.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:7

    Topics: Anoikis; Breast Neoplasms; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Factor; Epithelial Cells; Genes, Dominant; Humans; Lysophospholipids; Neoplasm Invasiveness; p21-Activated Kinases; Phosphorylation; Plasmids; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Signal Transduction; Time Factors; Transfection

2005
beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts.
    The Journal of biological chemistry, 2005, Sep-16, Volume: 280, Issue:37

    Topics: Animals; Arrestins; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Cells, Cultured; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Epitopes; ErbB Receptors; Fibroblasts; Flavonoids; Gene Expression Regulation; Humans; Lysophospholipids; Mice; Mice, Knockout; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Phosphorylation; Quinazolines; ras Proteins; RNA; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrphostins

2005
Lysophosphatidic acid cooperates with EGF in inducing branching morphogenesis of embryonic mouse salivary epithelium.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2006, Volume: 235, Issue:2

    Topics: Animals; Cell Proliferation; DNA; Epidermal Growth Factor; Epithelium; Hot Temperature; Lipid Metabolism; Lysophospholipids; Mice; Mice, Inbred ICR; Morphogenesis; Receptors, Lysophosphatidic Acid; Salivary Glands; Trypsin

2006
Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.
    Cell structure and function, 2006, Volume: 31, Issue:1

    Topics: Alanine; Amino Acid Sequence; Animals; Anisomycin; Cell Line; Chlorocebus aethiops; Cytoplasm; Epidermal Growth Factor; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ionophores; Lysophospholipids; Male; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Peptide Fragments; Phosphorylation; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Vero Cells

2006
Small Rho GTPases are important for acinus formation in a human salivary gland cell line.
    Cell and tissue research, 2006, Volume: 325, Issue:3

    Topics: Actins; Cell Culture Techniques; Cell Line; Epidermal Growth Factor; Extracellular Matrix; Fibroblast Growth Factor 2; Fluorescent Antibody Technique, Direct; Fluorescent Dyes; Humans; Immunohistochemistry; Lysophospholipids; Microscopy, Confocal; Monomeric GTP-Binding Proteins; Phalloidine; Rhodamines; Salivary Glands; Signal Transduction

2006
Regulation of lysophosphatidic acid-induced epidermal growth factor receptor transactivation and interleukin-8 secretion in human bronchial epithelial cells by protein kinase Cdelta, Lyn kinase, and matrix metalloproteinases.
    The Journal of biological chemistry, 2006, Jul-14, Volume: 281, Issue:28

    Topics: Bronchi; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Lysophospholipids; Matrix Metalloproteinases; Protein Kinase C-delta; src-Family Kinases; Transcriptional Activation

2006
Differential FAK phosphorylation at Ser-910, Ser-843 and Tyr-397 induced by angiotensin II, LPA and EGF in intestinal epithelial cells.
    Cellular signalling, 2007, Volume: 19, Issue:5

    Topics: Angiotensins; Animals; Carbachol; Cell Line; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intestinal Mucosa; Ionomycin; Kinetics; Lysophospholipids; Phosphorylation; Protein Kinase C; Rats; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Tyrosine

2007
Lysophosphatidic acid promoting corneal epithelial wound healing by transactivation of epidermal growth factor receptor.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:2

    Topics: Animals; Cell Culture Techniques; Cell Movement; Debridement; Epidermal Growth Factor; Epithelium, Corneal; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Oncogene Protein v-akt; Organ Culture Techniques; Phosphatidylinositol 3-Kinases; Phosphorylation; Swine; Transcriptional Activation; Wound Healing

2007
Inhibition of calcium-independent phospholipase A2 suppresses proliferation and tumorigenicity of ovarian carcinoma cells.
    The Biochemical journal, 2007, Sep-15, Volume: 406, Issue:3

    Topics: Animals; Apoptosis; Blotting, Western; Calcium; Cell Division; Cell Proliferation; Cyclins; Cytosol; Epidermal Growth Factor; Female; G2 Phase; Group VI Phospholipases A2; Humans; Lysophospholipids; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthalenes; Ovarian Neoplasms; Phospholipases A; Phospholipases A2; Pyrones; RNA, Small Interfering; S Phase; Tumor Cells, Cultured

2007
Lysophosphatidic acid decreases epidermal growth factor receptor binding in airway epithelial cells.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:1

    Topics: Bronchi; Cell Line, Tumor; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Fatty Acids; Humans; Lung; Lysophospholipids; Phosphorylation; Protein Binding; Radioligand Assay; Receptors, G-Protein-Coupled; Time Factors

2007
Multiple actions of lysophosphatidic acid on fibroblasts revealed by transcriptional profiling.
    BMC genomics, 2008, Aug-14, Volume: 9

    Topics: Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Cytoskeleton; Embryo, Mammalian; Epidermal Growth Factor; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Lysophospholipids; Mice; Oligonucleotide Array Sequence Analysis; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA; Time Factors

2008
ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65.
    The Journal of cell biology, 2008, Sep-08, Volume: 182, Issue:5

    Topics: Animals; Brefeldin A; Cell Movement; Cell Polarity; Centrosome; Enzyme Activation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Golgi Apparatus; Golgi Matrix Proteins; Interphase; Lysophospholipids; Membrane Proteins; Mitogens; Phosphorylation; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Rats

2008
LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites.
    Carcinogenesis, 2009, Volume: 30, Issue:3

    Topics: Ascites; Cell Line, Tumor; Cell Movement; Collagen; Drug Combinations; Epidermal Growth Factor; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoxazoles; Laminin; Lysophospholipids; Neoplasm Invasiveness; Pancreatic Neoplasms; Pertussis Toxin; Propionates; Proteoglycans; Receptors, Lysophosphatidic Acid; rhoA GTP-Binding Protein; RNA, Small Interfering

2009
Effect of inhibitors of mitogen-activated protein kinase kinase on alpha(1B)-adrenoceptor phosphorylation.
    Autonomic & autacoid pharmacology, 2009, Volume: 29, Issue:1-2

    Topics: Androstadienes; Animals; Butadienes; Calcium Signaling; Cell Line; Cricetinae; Endothelin-1; Epidermal Growth Factor; Flavonoids; Genistein; Humans; Indoles; Lysophospholipids; Maleimides; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Norepinephrine; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Adrenergic, alpha-1; RNA, Small Interfering; Staurosporine; Tetradecanoylphorbol Acetate; Wortmannin

2009
Protein tyrosine phosphatase-alpha complexes with the IGF-I receptor and undergoes IGF-I-stimulated tyrosine phosphorylation that mediates cell migration.
    American journal of physiology. Cell physiology, 2009, Volume: 297, Issue:1

    Topics: Animals; Cell Line; Cell Movement; Epidermal Growth Factor; Fibroblast Growth Factor 1; Fibroblasts; Focal Adhesion Kinase 1; Insulin-Like Growth Factor I; Lysophospholipids; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptor, IGF Type 1; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate; Transfection; Tyrosine

2009
Epidermal growth factor increases lysophosphatidic acid production in human ovarian cancer cells: roles for phospholipase D2 and receptor transactivation.
    American journal of physiology. Cell physiology, 2010, Volume: 298, Issue:1

    Topics: Cell Line, Tumor; Epidermal Growth Factor; ErbB Receptors; Female; Genetic Vectors; Humans; Lysophospholipids; Ovarian Neoplasms; Pertussis Toxin; Phospholipase D; Protein-Tyrosine Kinases; Receptor Cross-Talk; Receptors, Lysophosphatidic Acid; Transcriptional Activation; Transfection

2010
Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid.
    Molecular cancer, 2010, Jan-14, Volume: 9

    Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Female; GTP-Binding Proteins; Hepatocyte Growth Factor; Humans; Interleukin-8; Lysophospholipids; Neoplasm Invasiveness; NF-kappa B; Phosphotyrosine; Transcription Factor AP-1

2010
Non-transactivational, dual pathways for LPA-induced Erk1/2 activation in primary cultures of brown pre-adipocytes.
    Experimental cell research, 2010, Oct-01, Volume: 316, Issue:16

    Topics: Adipocytes, Brown; Animals; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Immunoblotting; Lysophospholipids; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Receptors, G-Protein-Coupled; Receptors, Platelet-Derived Growth Factor; Transcriptional Activation

2010
MicroRNA-30c-2* expressed in ovarian cancer cells suppresses growth factor-induced cellular proliferation and downregulates the oncogene BCL9.
    Molecular cancer research : MCR, 2011, Volume: 9, Issue:12

    Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genome, Human; Humans; Lysophospholipids; MicroRNAs; Neoplasm Proteins; Ovarian Neoplasms; Platelet-Derived Growth Factor; Receptors, Lysophosphatidic Acid; Signal Transduction; Transcription Factors; Transfection

2011
Real-time motion analysis reveals cell directionality as an indicator of breast cancer progression.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Disease Progression; Epidermal Growth Factor; Female; Humans; Lysophospholipids; Neoplasm Metastasis; Phenotype; Tumor Stem Cell Assay

2013
ERK-associated changes in E2F4 phosphorylation, localization and transcriptional activity during mitogenic stimulation in human intestinal epithelial crypt cells.
    BMC cell biology, 2013, Aug-06, Volume: 14

    Topics: Adenoma; Butadienes; Cell Cycle; Cell Line; Cell Proliferation; Cells, Cultured; Colorectal Neoplasms; E2F4 Transcription Factor; Enzyme Inhibitors; Epidermal Growth Factor; Glycogen Synthase Kinase 3; Humans; Intestinal Mucosa; Lysophospholipids; MAP Kinase Signaling System; Mitogens; Nitriles; Phosphorylation; Transcription, Genetic

2013
LPA, HGF, and EGF utilize distinct combinations of signaling pathways to promote migration and invasion of MDA-MB-231 breast carcinoma cells.
    BMC cancer, 2013, Oct-27, Volume: 13

    Topics: Actins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; Female; Hepatocyte Growth Factor; Humans; Lysophospholipids; Mitogen-Activated Protein Kinases; Myosin-Light-Chain Kinase; Myosins; Neoplasm Invasiveness; rac GTP-Binding Proteins; rho GTP-Binding Proteins; Signal Transduction

2013
FGF7 signals are relayed to autocrine EGF family growth factors to induce branching morphogenesis of mouse salivary epithelium.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2014, Volume: 243, Issue:4

    Topics: Animals; Autocrine Communication; Epidermal Growth Factor; Epithelium; Fibroblast Growth Factor 7; Lysophospholipids; Mice; Morphogenesis; Salivary Glands

2014
Positive and Negative Cross-Talk between Lysophosphatidic Acid Receptor 1, Free Fatty Acid Receptor 4, and Epidermal Growth Factor Receptor in Human Prostate Cancer Cells.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 359, Issue:1

    Topics: beta-Arrestin 2; Cell Movement; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Gene Knockdown Techniques; Humans; Lysophospholipids; Male; Prostatic Neoplasms; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid

2016
Platelets Promote Metastasis via Binding Tumor CD97 Leading to Bidirectional Signaling that Coordinates Transendothelial Migration.
    Cell reports, 2018, Apr-17, Volume: 23, Issue:3

    Topics: Antigens, CD; Blood Platelets; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Dimerization; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Humans; Lysophospholipids; Platelet Activation; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; RNA Interference; RNA, Small Interfering; Signal Transduction; Tight Junctions; Transforming Growth Factor beta

2018
Role of lysophosphatidic acid in proliferation and differentiation of intestinal epithelial cells.
    PloS one, 2019, Volume: 14, Issue:4

    Topics: Animals; Cell Differentiation; Cell Proliferation; Epidermal Growth Factor; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Intestinal Mucosa; Lysophospholipids; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Organoids; Phosphorylation; Receptors, Lysophosphatidic Acid; Tissue Culture Techniques

2019
The effect of lysophosphatidic acid-supplemented culture medium on human immature oocytes matured in vitro.
    Reproductive biology and endocrinology : RB&E, 2021, Jun-04, Volume: 19, Issue:1

    Topics: Adult; Cell Cycle; Culture Media; Cumulus Cells; Down-Regulation; Epidermal Growth Factor; Estrogens; Female; Follicle Stimulating Hormone; Gap Junctions; Gene Expression; Gene Ontology; Humans; In Vitro Oocyte Maturation Techniques; Luteinizing Hormone; Lysophospholipids; Mitogen-Activated Protein Kinases; Oocytes; Ovarian Follicle; Signal Transduction; Up-Regulation; Young Adult

2021