Compounds > lysine
Page last updated: 2024-08-17

lysine and zidovudine

lysine has been researched along with zidovudine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's5 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
de Clercq, E; Jansen, RW; Meijer, DK; Molema, G; Pauwels, R1
Neitzel, H; Nündel, M; Riedel, E; Schultis, HK; von Baeyer, H1
Drake, RR; Hong, H; Hume, SD; Milne, GW; Neamati, N; Pilon, AA; Pommier, Y; Sunthankar, P1
Kosa, JL; Sweasy, JB1
Adman, ET; Isaacs, SJ; Kim, B; Tran, NH; Weiss, KK1
Bacheler, L; Koontz, D; Mellors, JW; Parikh, UM1
Mellors, JW; Parikh, UM; Sheen, CW; Sluis-Cremer, N; Torres, PS; Zelina, S1
Garforth, SJ; Parniak, MA; Prasad, VR1

Other Studies

10 other study(ies) available for lysine and zidovudine

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Targeting of antiviral drugs to T4-lymphocytes. Anti-HIV activity of neoglycoprotein-AZTMP conjugates in vitro.
    Biochemical pharmacology, 1990, Dec-15, Volume: 40, Issue:12

    Topics: Antiviral Agents; CD4-Positive T-Lymphocytes; Dideoxynucleotides; Drug Carriers; Glycoproteins; HIV Infections; Humans; In Vitro Techniques; Lysine; Serum Albumin; Thymine Nucleotides; Zidovudine

1990
Covalent coupling of nucleosides to low density lipoprotein (LDL) generates macrophage specific (drug)-carriers.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:8

    Topics: Animals; Apolipoproteins B; Autoradiography; Biological Transport; Cells, Cultured; Drug Carriers; Endocytosis; Humans; Lipoproteins, LDL; Lysine; Macrophages; Mice; Thymidine; Zidovudine

1993
Identification of a nucleotide binding site in HIV-1 integrase.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Apr-14, Volume: 95, Issue:8

    Topics: Affinity Labels; Amino Acid Sequence; Base Sequence; Binding Sites; Computer Simulation; Conserved Sequence; Dideoxynucleotides; DNA Primers; HIV Integrase; HIV-1; Hydrogen Bonding; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Protein Structure, Secondary; Recombinant Proteins; Thymine Nucleotides; Virus Replication; Zidovudine

1998
The E249K mutator mutant of DNA polymerase beta extends mispaired termini.
    The Journal of biological chemistry, 1999, Dec-10, Volume: 274, Issue:50

    Topics: Amino Acid Substitution; Base Sequence; DNA; DNA Polymerase beta; DNA Primers; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Mutagenesis; Nucleic Acid Conformation; Phenotype; Protein Structure, Secondary; Recombinant Fusion Proteins; Simplexvirus; Thymidine Kinase; Zidovudine

1999
Molecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions.
    Biochemistry, 2000, Sep-05, Volume: 39, Issue:35

    Topics: Amino Acid Substitution; Anti-HIV Agents; Base Pair Mismatch; Binding Sites; Dideoxynucleotides; DNA Mutational Analysis; DNA Primers; Glutamine; Glycine; HIV Reverse Transcriptase; Humans; Lac Operon; Lysine; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein Structure, Secondary; RNA; Substrate Specificity; Templates, Genetic; Thymine Nucleotides; Tryptophan; Zidovudine

2000
The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations.
    Journal of virology, 2006, Volume: 80, Issue:10

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Arginine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Organophosphonates; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Tenofovir; Thymidine; Zalcitabine; Zidovudine

2006
Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleosides; Dideoxynucleotides; Drug Resistance, Multiple, Viral; Genotype; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lysine; Mutagenesis, Site-Directed; Organophosphonates; Phenotype; Reverse Transcriptase Inhibitors; Tenofovir; Thymine Nucleotides; Zidovudine

2007
Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase.
    PloS one, 2008, Apr-30, Volume: 3, Issue:4

    Topics: Amino Acid Substitution; Catalysis; Diphosphates; HIV Reverse Transcriptase; Lysine; Models, Molecular; Mutant Proteins; Protein Structure, Tertiary; Substrate Specificity; Zidovudine

2008