Page last updated: 2024-08-17

lysine and transforming growth factor beta

lysine has been researched along with transforming growth factor beta in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (5.36)	18.2507
2000's	28 (50.00)	29.6817
2010's	16 (28.57)	24.3611
2020's	9 (16.07)	2.80

Authors

Authors	Studies
Acil, Y; Bätge, B; Müller, PK; Seitzer, U	1
Ansorge, S; Bank, U; Born, I; Bühling, F; Faust, J; Neubert, K; Reinhold, D; Täger, M	1
Horiuchi, S; Ikeda, K; Kushiro, M; Makino, H; Shikata, K; Sugimoto, H	1
Agarwal, S; Beckman, EJ; Piesco, NP; Zhang, JY	1
Ansorge, S; Arndt, M; Faust, J; Lendeckel, U; Neubert, K; Reinhold, D; Spiess, A	2
Ansorge, S; Born, I; Brocke, S; Faust, J; Gado, A; Izikson, L; Martin, R; Neubert, K; Quigley, L; Reinhold, D; Steinbrecher, A; Tresser, N	1
Bridle, KR; Crawford, DH; Powell, LW; Ramm, GA	1
Anderson, JM; Scivittaro, V; Weiss, MF	1
Bonni, S; Luo, K; Stroschein, SL; Wrana, JL	1
Ericsson, J; Grönroos, E; Heldin, CH; Hellman, U	1
Brunicardi, FC; Feng, XH; Liang, M; Liang, YY; Lin, X; Melchior, F	1
Chang, C; Derynck, R; Lee, PS; Liu, D	1
Adam, AG; Baddour, NM; El Nahas, AM; El-Koraie, AF; Griffin, M; Johnson, TS; Njloma, M; Skill, NJ	1
Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC	1
Bae, SC; Choi, JK; Jeon, EJ; Jin, YH; Kim, WJ; Lee, KY; Lee, YH; Li, QL	1
Amadio, L; Di Mario, U; Iacobini, C; Menini, S; Oddi, G; Olivieri, A; Pesce, C; Pricci, F; Pugliese, G; Ricci, C; Sorcini, M	1
Chang, CC; Chen, RH; Fang, HI; Lin, DY; Shih, HM	1
Ericsson, J; Grönroos, E; Heldin, CH; Simonsson, M	1
Amadio, L; Di Pippo, C; Iacobini, C; Menini, S; Oddi, G; Pricci, F; Pugliese, F; Pugliese, G; Ricci, C; Sorcini, M	1
Alfano, M; Contini, P; Poggi, A; Zocchi, MR	1
Imoto, S; Matsuda, T; Sekine, Y; Sugiyama, K	1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, N	1
Bonni, S; Chan, A; Hsu, YH; Netherton, SJ; Pot, I; Sarker, KP	1
Ansorge, S; Bank, U; Faust, J; Fuchs, P; Heimburg, A; Helmuth, M; Lendeckel, U; Neubert, K; Reinhold, D; Sens, B; Stefin, S; Täger, M	1
Bryan, B; Feng, XH; Liang, M; Lin, X; Liu, M; Luo, K; Wrighton, KH	1
Izuhara, Y; Miyata, T; Nangaku, M; Ohtomo, S; Strihou, Cv; Takizawa, S	1
Akhurst, RJ; Derynck, R; Kang, JS; Saunier, EF	1
Grimsby, S; Heldin, CH; Landström, M; Marcusson, A; Schuster, N; Sorrentino, A; Thakur, N; von Bulow, V; Zhang, S	1
Konikoff, CE; Newfeld, SJ; Wisotzkey, RG	2
Fatyol, K; Jin, C; Liu, Z; Wang, X; Yamashita, M; Zhang, YE	1
Fan, Y; Fu, S; Mao, R; Mou, Y; Yang, J; Zhang, H	1
Chan, LY; Cheng, AS; Lai, KN; Lan, HY; Leung, JC; Lin, M; Tang, SC	1
Bandinelli, S; Corsi, AM; Crasto, CL; Dalal, M; Ferrucci, L; Guralnik, JM; Semba, RD; Sun, K	1
Boddeke, E; Copray, S; Olah, M; Sher, F	1
Berezov, A; Cai, Z; Chen, C; Gao, Y; Greene, MI; Hancock, WW; Karger, BL; Li, B; Li, Z; Liu, Y; Song, X; Wang, Q; Wells, AD; Wu, SL; Xiao, Y; Xu, C; Zhang, H; Zhou, Z	1
Hara, S; Nagashima, H; Nagata, M; Umeyama, K; Yokoo, T	1
Campbell, DG; Cozza, G; Gourlay, R; Herhaus, L; Perez-Oliva, AB; Pinna, LA; Sapkota, GP; Weidlich, S	1
Chen, IT; Chen, NJ; Hsu, PH; Hsu, WC; Tseng, PH	1
Eichhorn, PJ; Iyengar, PV; Jaynes, P; Lama, D; Law, KP; Lim, YP; Rodon, L; Seoane, J; Verma, C	1
Choi, SI; Kim, EK; Kim, KS; Lee, GH; Maeng, YS	1
Fan, Z; Fang, M; Hao, C; Li, J; Li, M; Tian, W; Wu, X; Xu, H; Xu, Y; Zhang, L; Zhou, B	1
Antonoglou, A; Brown, PJ; Elkouris, M; Kontaki, H; Nikolaou, KC; Panayotou, G; Samiotaki, M; Saviolaki, D; Sideras, P; Stavropoulos, A; Szantai, E; Talianidis, I	1
Bergh, A; Hamidi, A; Heldin, CH; Itoh, S; Landström, M; Marcusson, A; Song, J; Thakur, N	1
Gong, ZY; Liu, L; Liu, X; Wang, YX; Wu, YN; Xu, H	1
Chang, Y; Chen, L; Guan, G; Guo, A; Guo, H; Kang, Y; Wu, X; Xu, H; Xu, S; Ye, Y; Zhang, Y; Zhao, X	1
Bae, JS; Choi, EY; Kim, H; Kim, HN; Lee, W; Park, HH; Shin, H; Yoo, Y	1
Chen, S; Dai, X; Gong, Y; Huang, H; Li, H; Zhao, Y	1
Baldo, G; Coitinho, AS; de Lima Rosa, G; Faverzani, J; Gome Dos Reis, B; Gonzalez, EA; Guerreiro, G; Moura, AP; Sitta, A; Vargas, CR; Volfart, V; Wajner, M	1
Chen, J; Hu, Q; Liu, G; Liu, X; Zhang, B; Zhou, J	1
Agborbesong, E; Li, LX; Li, X; Zhang, L; Zhang, X; Zhou, JX	1
Chen, Z; Li, X; Xu, Z; Yu, J; Yuan, L	1
Ardjmand, A; Ghavipanjeh, G; Jozi, F; Kheiripour, N; Nasehi, Z; Shahaboddin, ME; Taheri, MA	1
Dalpatraj, N; Naik, A; Thakur, N	1
Kang, L; Liang, Z; Wang, X; Xiang, J; Yang, G; Yang, S	1

Other Studies

56 other study(ies) available for lysine and transforming growth factor beta

Article	Year
Transforming growth factor beta 1 influences lysyl hydroxylation of collagen I and reduces steady-state levels of lysyl hydroxylase mRNA in human osteoblast-like cells. European journal of clinical investigation, 1995, Volume: 25, Issue:12 Topics: Adult; Blotting, Northern; Cloning, Molecular; Collagen; DNA Probes; Extracellular Matrix; Gene Expression Regulation; Glycosylation; Humans; Hydroxylation; Hydroxylysine; Lysine; Osteoblasts; Osteogenesis Imperfecta; Procollagen; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Protein Processing, Post-Translational; RNA, Messenger; Transforming Growth Factor beta	1995
Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-beta 1 (TGF-beta 1) in stimulated mouse splenocytes and thymocytes. Immunology letters, 1997, Volume: 58, Issue:1 Topics: Animals; Cell Division; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Interleukins; Lysine; Mice; Mice, Inbred BALB C; Protease Inhibitors; Pyrrolidines; Spleen; Thiazoles; Thymus Gland; Transforming Growth Factor beta	1997
Accumulation of Nsigma-(carboxy-methyl)lysine and changes in glomerular extracellular matrix components in Otsuka Long-Evans Tokushima fatty rat: a model of spontaneous NIDDM. Nephron, 1998, Volume: 79, Issue:4 Topics: Animals; Diabetes Mellitus, Type 2; Extracellular Matrix; Fluorescent Antibody Technique; Glycation End Products, Advanced; Immunoenzyme Techniques; Kidney Glomerulus; Lysine; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Time Factors; Transforming Growth Factor beta	1998
A new peptide-based urethane polymer: synthesis, biodegradation, and potential to support cell growth in vitro. Biomaterials, 2000, Volume: 21, Issue:12 Topics: Absorbable Implants; Animals; Biocompatible Materials; Bone Marrow Cells; Bone Substitutes; Cell Adhesion; Cell Division; Cells, Cultured; Collagen; Lysine; Materials Testing; Polyurethanes; Rabbits; RNA, Messenger; Stromal Cells; Transforming Growth Factor beta	2000
Specific inhibitors of dipeptidyl peptidase IV suppress mRNA expression of DP IV/CD26 and cytokines. Advances in experimental medicine and biology, 2000, Volume: 477 Topics: Autocrine Communication; Dipeptidyl Peptidase 4; Enzyme Induction; Feedback; G1 Phase; Humans; Interferon-gamma; Interleukin-12; Interleukin-2; Lymphocyte Activation; Lysine; Pokeweed Mitogens; RNA, Messenger; Serine Proteinase Inhibitors; T-Lymphocytes; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1	2000
Dipeptidyl peptidase IV (DP IV/CD26) mRNA expression in PWM-stimulated T-cells is suppressed by specific DP IV inhibition, an effect mediated by TGF-beta(1). Biochemical and biophysical research communications, 2000, Aug-02, Volume: 274, Issue:2 Topics: Antibodies; Cells, Cultured; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression; Humans; Interferon-gamma; Interleukin-2; Lysine; Pokeweed Mitogens; Protease Inhibitors; RNA, Messenger; T-Lymphocytes; Thiazoles; Transforming Growth Factor beta	2000
Targeting dipeptidyl peptidase IV (CD26) suppresses autoimmune encephalomyelitis and up-regulates TGF-beta 1 secretion in vivo. Journal of immunology (Baltimore, Md. : 1950), 2001, Feb-01, Volume: 166, Issue:3 Topics: Animals; Cell Division; Cells, Cultured; Dipeptidyl Peptidase 4; Encephalomyelitis, Autoimmune, Experimental; Enzyme Activation; Female; Freund's Adjuvant; Growth Inhibitors; Immunosuppression Therapy; Injections, Intraperitoneal; Injections, Subcutaneous; Lymphocyte Activation; Lysine; Mice; Myelin Basic Protein; Protease Inhibitors; Pyrrolidines; T-Lymphocyte Subsets; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation	2001
Role of myofibroblasts in tumour encapsulation of hepatocellular carcinoma in haemochromatosis. Liver, 2001, Volume: 21, Issue:2 Topics: Actins; Aged; Carcinoma, Hepatocellular; Cell Count; Fibroblasts; Hemochromatosis; Humans; Immunohistochemistry; In Situ Hybridization; Liver Neoplasms; Lysine; Male; Malondialdehyde; Middle Aged; Muscle, Smooth; Procollagen; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta	2001
Oxidative stress and increased expression of growth factors in lesions of failed hemodialysis access. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:5 Topics: Adult; Aged; Arteriovenous Anastomosis; Arteriovenous Fistula; Arteriovenous Shunt, Surgical; Biomarkers; Constriction, Pathologic; Endothelin-1; Female; Growth Substances; Humans; Hyperplasia; Iron; Kidney Failure, Chronic; Lipid Peroxidation; Lysine; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Platelet-Derived Growth Factor; Polytetrafluoroethylene; Renal Dialysis; Transforming Growth Factor beta; Tunica Intima; Vascular Patency	2001
Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN. Genes & development, 2001, Nov-01, Volume: 15, Issue:21 Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Cell Division; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Deletion; Humans; Intracellular Signaling Peptides and Proteins; Ligands; Lysine; Models, Biological; Models, Genetic; Molecular Sequence Data; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins; Retroviridae; Signal Transduction; Smad2 Protein; Smad3 Protein; Time Factors; Trans-Activators; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ubiquitin	2001
Control of Smad7 stability by competition between acetylation and ubiquitination. Molecular cell, 2002, Volume: 10, Issue:3 Topics: Acetylation; Activin Receptors, Type I; Amino Acid Sequence; Animals; Cell Line; DNA-Binding Proteins; Humans; Ligases; Lysine; Molecular Sequence Data; Mutation; Nuclear Proteins; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Signal Transduction; Smad7 Protein; Trans-Activators; Transforming Growth Factor beta; Ubiquitin; Ubiquitin-Protein Ligases	2002
Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4. The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21 Topics: Amino Acid Sequence; Animals; Cell Line; CHO Cells; Conserved Sequence; Cricetinae; DNA-Binding Proteins; Drug Stability; Embryo, Mammalian; Gene Deletion; Genes, Tumor Suppressor; HeLa Cells; Humans; Immunosorbent Techniques; Kidney; Ligases; Luciferases; Lung; Lysine; Mink; Molecular Sequence Data; Mutagenesis; Recombinant Fusion Proteins; Response Elements; Saccharomyces cerevisiae; Signal Transduction; Smad4 Protein; SUMO-1 Protein; Trans-Activators; Transcription, Genetic; Transfection; Transforming Growth Factor beta; Ubiquitin-Conjugating Enzymes	2003
Sumoylation of Smad4, the common Smad mediator of transforming growth factor-beta family signaling. The Journal of biological chemistry, 2003, Jul-25, Volume: 278, Issue:30 Topics: Active Transport, Cell Nucleus; Animals; Arginine; Blotting, Western; Carrier Proteins; COS Cells; DNA-Binding Proteins; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Ligases; Lysine; Microscopy, Fluorescence; Nerve Growth Factors; Plasmids; Poly-ADP-Ribose Binding Proteins; Precipitin Tests; Protein Inhibitors of Activated STAT; Protein Processing, Post-Translational; Protein Structure, Tertiary; RNA, Complementary; Signal Transduction; Smad Proteins; Smad4 Protein; SUMO-1 Protein; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Xenopus; Xenopus Proteins	2003
Tissue transglutaminase and the progression of human renal scarring. Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:8 Topics: Animals; Antibodies; Biopsy; Cicatrix; Cross-Linking Reagents; Extracellular Matrix; Fibrosis; Humans; Immunohistochemistry; In Situ Hybridization; Kidney; Lysine; Mice; Microscopy, Fluorescence; Retrospective Studies; RNA, Messenger; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transglutaminases	2003
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:12 Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine	2003
Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation. The Journal of biological chemistry, 2004, Jul-09, Volume: 279, Issue:28 Topics: Acetylation; Acetyltransferases; Animals; Cell Cycle Proteins; Cell Line; Core Binding Factor Alpha 3 Subunit; DNA-Binding Proteins; Genes, Reporter; Histone Acetyltransferases; Humans; Hydroxamic Acids; Lysine; p300-CBP Transcription Factors; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; Signal Transduction; Transcription Factors; Transcriptional Activation; Transforming Growth Factor beta; Ubiquitin; Ubiquitin-Protein Ligases	2004
Galectin-3/AGE-receptor 3 knockout mice show accelerated AGE-induced glomerular injury: evidence for a protective role of galectin-3 as an AGE receptor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:14 Topics: Aldehydes; Animals; Cell Death; Cell Proliferation; Extracellular Matrix Proteins; Galectin 3; Glycation End Products, Advanced; Kidney; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Kinetics; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Proteinuria; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transforming Growth Factor beta	2004
Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4. The Journal of biological chemistry, 2005, Mar-18, Volume: 280, Issue:11 Topics: Adaptor Proteins, Signal Transducing; Animals; Arginine; Blotting, Western; Carrier Proteins; Cell Line; Chromatin; Chromatin Immunoprecipitation; Co-Repressor Proteins; COS Cells; DNA-Binding Proteins; Gene Deletion; Genes, Reporter; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Luciferases; Lysine; Microscopy, Fluorescence; Molecular Chaperones; Mutation; Nuclear Proteins; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; RNA Interference; Signal Transduction; Smad4 Protein; Small Ubiquitin-Related Modifier Proteins; SUMO-1 Protein; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transfection; Transforming Growth Factor beta; Two-Hybrid System Techniques	2005
The balance between acetylation and deacetylation controls Smad7 stability. The Journal of biological chemistry, 2005, Jun-10, Volume: 280, Issue:23 Topics: Acetylation; Cell Line; DNA; DNA-Binding Proteins; Glutathione Transferase; Histone Deacetylases; Histones; Humans; Immunoblotting; Immunoprecipitation; Lysine; Models, Biological; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; RNA, Small Interfering; Signal Transduction; Smad7 Protein; Time Factors; Trans-Activators; Transfection; Transforming Growth Factor beta; Ubiquitin	2005
Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice. American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:3 Topics: Age Factors; Aging; Aldehydes; Animals; Body Weight; Dinoprost; Extracellular Matrix; Galectin 3; Glomerulonephritis; Glycation End Products, Advanced; Kidney Glomerulus; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
Pertussis toxin (PTX) B subunit and the nontoxic PTX mutant PT9K/129G inhibit Tat-induced TGF-beta production by NK cells and TGF-beta-mediated NK cell apoptosis. Journal of immunology (Baltimore, Md. : 1950), 2005, May-15, Volume: 174, Issue:10 Topics: Adjuvants, Immunologic; Amino Acid Substitution; Apoptosis; bcl-X Protein; Cells, Cultured; Down-Regulation; Enzyme Activation; Gene Products, tat; Glycine; HIV Infections; HIV-1; Humans; Killer Cells, Natural; Lysine; Pertussis Toxin; Phosphorylation; Protein Serine-Threonine Kinases; Protein Subunits; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; tat Gene Products, Human Immunodeficiency Virus; Transcription Factor AP-1; Transcription, Genetic; Transforming Growth Factor beta; Vaccines, Subunit	2005
Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-beta signaling. FEBS letters, 2005, May-23, Volume: 579, Issue:13 Topics: Amino Acid Sequence; Cell Line, Tumor; DNA-Binding Proteins; Fluorescent Antibody Technique, Indirect; Humans; Lysine; Molecular Sequence Data; Mutation; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad3 Protein; Trans-Activators; Transcription, Genetic; Transforming Growth Factor beta	2005
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis. Oncology reports, 2005, Volume: 14, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Extracellular Matrix; Fibroblast Growth Factor 2; Formaldehyde; Humans; Immunohistochemistry; In Vitro Techniques; Laminin; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Osteosarcoma; Plant Extracts; Platelet-Derived Growth Factor; Proline; Proteoglycans; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A	2005
Sumoylated SnoN represses transcription in a promoter-specific manner. The Journal of biological chemistry, 2006, Nov-03, Volume: 281, Issue:44 Topics: Amino Acid Sequence; Animals; Cell Line; Chickens; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mice; Molecular Sequence Data; Myogenin; Promoter Regions, Genetic; Protein Binding; Protein Inhibitors of Activated STAT; Proto-Oncogene Proteins; Sequence Alignment; SUMO-1 Protein; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta	2006
Triggering endogenous immunosuppressive mechanisms by combined targeting of Dipeptidyl peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/ CD13)--a novel approach for the treatment of inflammatory bowel disease. International immunopharmacology, 2006, Dec-20, Volume: 6, Issue:13-14 Topics: Animals; Body Weight; CD13 Antigens; Colitis; Colon; Cytokines; Dextran Sulfate; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Forkhead Transcription Factors; Gene Expression; Hydroxamic Acids; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lysine; Mice; Mice, Inbred BALB C; Protease Inhibitors; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta	2006
Transforming growth factor-beta-independent regulation of myogenesis by SnoN sumoylation. The Journal of biological chemistry, 2007, Mar-02, Volume: 282, Issue:9 Topics: Cell Line; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Muscle Development; Protein Inhibitors of Activated STAT; Proto-Oncogene Proteins; SUMO-1 Protein; Transforming Growth Factor beta; Ubiquitin-Protein Ligases	2007
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:4 Topics: Animals; Antimutagenic Agents; Arginine; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Blotting, Western; Chromatography, High Pressure Liquid; Cobalt; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Gene Expression; Glycation End Products, Advanced; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immediate-Early Proteins; Insulin-Like Growth Factor Binding Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; NADPH Oxidases; Obesity; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta	2008
The type I TGF-beta receptor is covalently modified and regulated by sumoylation. Nature cell biology, 2008, Volume: 10, Issue:6 Topics: Animals; Chlorocebus aethiops; COS Cells; Cytoplasm; Gene Expression Regulation; Humans; Lysine; Mice; Models, Biological; Neoplasm Metastasis; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; SUMO-1 Protein; Transforming Growth Factor beta	2008
The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner. Nature cell biology, 2008, Volume: 10, Issue:10 Topics: Animals; Apoptosis; Cell Line; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Lysine; MAP Kinase Kinase Kinases; Mice; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Smad2 Protein; TNF Receptor-Associated Factor 6; Transforming Growth Factor beta; Ubiquitin-Protein Ligases; Ubiquitination	2008
Lysine conservation and context in TGFbeta and Wnt signaling suggest new targets and general themes for posttranslational modification. Journal of molecular evolution, 2008, Volume: 67, Issue:4 Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Conserved Sequence; Dishevelled Proteins; Frizzled Receptors; Lysine; Molecular Sequence Data; Phosphoproteins; Protein Processing, Post-Translational; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Wnt Proteins	2008
TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta. Molecular cell, 2008, Sep-26, Volume: 31, Issue:6 Topics: Animals; Apoptosis; Cell Line; Enzyme Activation; Epithelium; Humans; JNK Mitogen-Activated Protein Kinases; Lysine; MAP Kinase Kinase Kinases; Mesoderm; Mice; p38 Mitogen-Activated Protein Kinases; Protein Binding; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad Proteins; TNF Receptor-Associated Factor 6; Transforming Growth Factor beta; Ubiquitination	2008
TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation. Cellular signalling, 2011, Volume: 23, Issue:1 Topics: Animals; Fibroblasts; HeLa Cells; Humans; I-kappa B Kinase; JNK Mitogen-Activated Protein Kinases; Lysine; MAP Kinase Kinase Kinases; Mice; Mutation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Smad Proteins; TNF Receptor-Associated Factor 6; Transcription Factor AP-1; Transforming Growth Factor beta; Ubiquitination	2011
Differential effects of advanced glycation end-products on renal tubular cell inflammation. Nephrology (Carlton, Vic.), 2011, Volume: 16, Issue:4 Topics: Anti-Inflammatory Agents; Cells, Cultured; Chemokine CCL2; Connective Tissue Growth Factor; Epithelial Cells; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Inflammation Mediators; Interleukin-6; Kidney Tubules, Proximal; Lysine; Nephritis, Interstitial; NF-kappa B; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Rosiglitazone; Serum Albumin; Serum Albumin, Bovine; Signal Transduction; Thiazolidinediones; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A	2011
Endogenous secretory receptor for advanced glycation end products is associated with low serum interleukin-1 receptor antagonist and elevated IL-6 in older community-dwelling adults. The journals of gerontology. Series A, Biological sciences and medical sciences, 2011, Volume: 66, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-18; Interleukin-1beta; Interleukin-6; Italy; Longitudinal Studies; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Interleukin-6; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Young Adult	2011
Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes. PloS one, 2012, Volume: 7, Issue:7 Topics: Animals; Apoptosis; Brain; Cell Cycle; Cell Differentiation; Cell Proliferation; Chromatin Immunoprecipitation; Enhancer of Zeste Homolog 2 Protein; Genome; Histones; Immunoglobulin G; Lysine; Mice; Mice, Inbred C57BL; Neural Stem Cells; Oligodendroglia; Polycomb Repressive Complex 2; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta	2012
Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function. Cell reports, 2012, Jun-28, Volume: 1, Issue:6 Topics: Acetylation; Amino Acid Sequence; Animals; DNA Mutational Analysis; Forkhead Transcription Factors; Humans; Jurkat Cells; Leucine Zippers; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Repressor Proteins; Structure-Activity Relationship; T-Lymphocytes, Regulatory; Transforming Growth Factor beta; Zinc Fingers	2012
Hippo pathway phylogenetics predicts monoubiquitylation of Salvador and Merlin/Nf2. PloS one, 2012, Volume: 7, Issue:12 Topics: Animals; Bayes Theorem; Cell Cycle Proteins; Drosophila melanogaster; Drosophila Proteins; Humans; Intracellular Signaling Peptides and Proteins; Likelihood Functions; Lysine; Neurofibromin 2; Phosphorylation; Phylogeny; Protein Serine-Threonine Kinases; Signal Transduction; Smad4 Protein; Transforming Growth Factor beta; Ubiquitin	2012
Diffuse glomerular nodular lesions in diabetic pigs carrying a dominant-negative mutant hepatocyte nuclear factor 1-alpha, an inheritant diabetic gene in humans. PloS one, 2014, Volume: 9, Issue:3 Topics: Animals; Animals, Genetically Modified; Collagen; Diabetes Mellitus; Genes, Dominant; Glycation End Products, Advanced; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Immunohistochemistry; Inheritance Patterns; Kidney Glomerulus; Lysine; Mutation; Sus scrofa; Transforming Growth Factor beta	2014
Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization. Science signaling, 2015, Apr-14, Volume: 8, Issue:372 Topics: Active Transport, Cell Nucleus; Animals; Casein Kinase II; Cell Line, Tumor; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; Deubiquitinating Enzymes; Embryo, Mammalian; Fibroblasts; HEK293 Cells; HeLa Cells; Humans; Immunoblotting; Lysine; Mice, Knockout; Microscopy, Fluorescence; Mutation; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA Interference; Serine; Transforming Growth Factor beta; Ubiquitin-Conjugating Enzymes	2015
Polyubiquitination of Transforming Growth Factor β-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4-mediated JNK and p38 MAPK Activation. Scientific reports, 2015, Jul-20, Volume: 5 Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Cell Line; Cytokines; Enzyme Activation; Humans; I-kappa B Kinase; JNK Mitogen-Activated Protein Kinases; Lysine; MAP Kinase Kinase Kinases; Mice; Molecular Sequence Data; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Sequence Alignment; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4; Transforming Growth Factor beta; Ubiquitination	2015
USP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination. Scientific reports, 2015, Oct-05, Volume: 5 Topics: Amino Acid Sequence; Cell Movement; HEK293 Cells; Humans; Kinetics; Lysine; Protein Structure, Tertiary; Proteolysis; Signal Transduction; Transforming Growth Factor beta; Ubiquitin-Protein Ligases; Ubiquitin-Specific Proteases; Ubiquitination	2015
Histone methylation levels correlate with TGFBIp and extracellular matrix gene expression in normal and granular corneal dystrophy type 2 corneal fibroblasts. BMC medical genomics, 2015, Nov-09, Volume: 8 Topics: Cornea; Corneal Dystrophies, Hereditary; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Gene Expression Regulation; Gene Knockdown Techniques; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Homozygote; Humans; Lysine; Methylation; Myeloid-Lymphoid Leukemia Protein; Protein Transport; Smad3 Protein; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1	2015
Myocardin-related transcription factor A (MRTF-A) plays an essential role in hepatic stellate cell activation by epigenetically modulating TGF-β signaling. The international journal of biochemistry & cell biology, 2016, Volume: 71 Topics: Animals; Cell Line; Epigenesis, Genetic; Hepatic Stellate Cells; Histones; Liver Cirrhosis; Lysine; Male; Methylation; Mice; Promoter Regions, Genetic; Rats; Signal Transduction; Trans-Activators; Transcriptional Activation; Transforming Growth Factor beta	2016
SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis. Cell reports, 2016, 06-21, Volume: 15, Issue:12 Topics: Acetylation; Animals; Bleomycin; Extracellular Matrix; Gene Expression Regulation; HeLa Cells; Histone-Lysine N-Methyltransferase; Humans; Lysine; Male; Methylation; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Nuclear Proteins; Protein Methyltransferases; Protein Stability; Pulmonary Fibrosis; Signal Transduction; Smad7 Protein; Transforming Growth Factor beta; Ubiquitin-Protein Ligases; Ubiquitination	2016
TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α. Science signaling, 2017, Jul-04, Volume: 10, Issue:486 Topics: Animals; Apoptosis; Cell Movement; Cells, Cultured; Class Ia Phosphatidylinositol 3-Kinase; Embryo, Mammalian; Fibroblasts; Humans; Lysine; Male; Mice; Mice, Knockout; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; TNF Receptor-Associated Factor 6; Transforming Growth Factor beta; Ubiquitination	2017
Studies on mechanism of free Nε-(carboxymethyl)lysine-induced toxic injury in mice. Journal of biochemical and molecular toxicology, 2019, Volume: 33, Issue:7 Topics: Animals; Female; Inflammation; Kidney; Liver; Lysine; Male; Mice; Oxidative Stress; Receptor for Advanced Glycation End Products; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2019
Loss of Gsdf leads to a dysregulation of Igf2bp3-mediated oocyte development in medaka. General and comparative endocrinology, 2019, 06-01, Volume: 277 Topics: Amino Acid Sequence; Animals; Cell Proliferation; Conserved Sequence; Evolution, Molecular; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Histones; Lysine; Male; Oocytes; Oogenesis; Oryzias; Ovary; Phylogeny; Proteomics; RNA-Binding Proteins; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta	2019
Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia. Science advances, 2020, Volume: 6, Issue:31 Topics: Acetylation; Antibodies, Neutralizing; Betacoronavirus; Biomarkers; Case-Control Studies; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Extracellular Matrix Proteins; Gene Expression; Humans; Intensive Care Units; Leukocyte Count; Leukocytes, Mononuclear; Lung; Lysine; NF-kappa B; Pandemics; Pneumonia, Viral; Primary Cell Culture; Prognosis; Protein Processing, Post-Translational; Respiratory Insufficiency; SARS-CoV-2; Severity of Illness Index; Transforming Growth Factor beta	2020
Overexpression of ring finger protein 20 inhibits the progression of liver fibrosis via mediation of histone H2B lysine 120 ubiquitination. Human cell, 2021, Volume: 34, Issue:3 Topics: Cell Movement; Cell Survival; Cells, Cultured; Disease Progression; Gene Expression; Histones; Humans; Interleukin-6; Liver Cirrhosis; Lysine; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Ubiquitination; Vascular Endothelial Growth Factor A	2021
Protective effects of L-carnitine on behavioral alterations and neuroinflammation in striatum of glutaryl-COA dehydrogenase deficient mice. Archives of biochemistry and biophysics, 2021, 09-30, Volume: 709 Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; Carnitine; Cathepsin D; Corpus Striatum; Glutaryl-CoA Dehydrogenase; Grooming; Inflammation; Interleukin-1beta; Locomotion; Lysine; Mice, Knockout; Neuroprotective Agents; Open Field Test; Transforming Growth Factor beta	2021
Lysine demethylase 3A is a positive regulator of cardiac myofibroblast transdifferentiation that increases Smad3 phosphorylation following transforming growth factor beta1 stimulation. Molecular biology reports, 2022, Volume: 49, Issue:4 Topics: Cell Transdifferentiation; Fibroblasts; Lysine; Myofibroblasts; Phosphorylation; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1	2022
Cross talk between lysine methyltransferase Smyd2 and TGF-β-Smad3 signaling promotes renal fibrosis in autosomal dominant polycystic kidney disease. American journal of physiology. Renal physiology, 2022, 08-01, Volume: 323, Issue:2 Topics: Animals; Cysts; Fibrosis; Histones; Kidney; Lysine; Methyltransferases; Mice; NIH 3T3 Cells; Polycystic Kidney Diseases; Polycystic Kidney, Autosomal Dominant; Rats; Smad3 Protein; Transforming Growth Factor beta	2022
BMP2 inhibits cell proliferation by downregulating EZH2 in gastric cancer. Cell cycle (Georgetown, Tex.), 2022, Volume: 21, Issue:21 Topics: Bone Morphogenetic Protein 2; Cell Line, Tumor; Cell Proliferation; Endothelial Cells; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Histones; Humans; Lysine; RNA, Small Interfering; Stomach Neoplasms; Transforming Growth Factor beta; Transforming Growth Factors	2022
L-Lysine Ameliorates Diabetic Nephropathy in Rats with Streptozotocin-Induced Diabetes Mellitus. BioMed research international, 2022, Volume: 2022 Topics: Animals; Antioxidants; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycation End Products, Advanced; Insulin; Kidney; Lipids; Lysine; Male; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A	2022
Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ. Gene, 2023, Aug-30, Volume: 879 Topics: Epigenesis, Genetic; Histones; Humans; Interferon-gamma; Lysine; Methylation; Protein Processing, Post-Translational; Transforming Growth Factor beta	2023
SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells. Cell death & disease, 2023, 09-30, Volume: 14, Issue:9 Topics: Epithelial Cells; Fibrosis; Humans; Lysine; Renal Insufficiency, Chronic; Sirtuin 2; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1	2023