Page last updated: 2024-08-17

lysine and tranexamic acid

lysine has been researched along with tranexamic acid in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199011 (28.21)18.7374
1990's11 (28.21)18.2507
2000's8 (20.51)29.6817
2010's7 (17.95)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Christensen, U1
Cederholm-Williams, SA; Swain, A1
Takada, A; Takada, Y3
Lubinus, J; Zimmermann, RE1
Matsuda, H; Ohashi, H; Takada, A; Takada, Y1
Markus, G; Priore, RL; Wissler, FC1
Christensen, U; Mølgaard, L1
Castellino, FJ; De Serrano, VS2
Anonick, PK; Gonias, SL; Vasudevan, J1
Gaffney, PJ; Longstaff, C1
De Marco, A; Laursen, RA; Llinás, M; Petros, AM1
Suenson, E; Thorsen, S1
Aoki, N; Matsuda, M; Sakata, Y; Tateno, K1
Fless, GM; Hoover-Plow, JL; Miles, LA; Plow, EF; Scanu, AM1
Rieks, M; Simmet, T; Syrovets, T; Tippler, B1
Fless, GM; Furbee, J; Meredith, SC; Santiago, JY1
Royston, D1
Baker, MS; O'Mullane, MJ1
Frank, S; Hrzenjak, A; Kostner, GM; Kostner, K; Sattler, W1
Hoover-Plow, J; Yuen, L1
Gaubatz, JW; Ghazzaly, KG; Guevara, J; Hoffman, AS; Hoogeveen, RC; Koschinsky, ML; Morrisett, JD; Pownall, HJ1
Austin, CA; Lakey, JH; Leontiou, C1
Bacsik, J; Brustowicz, RM; Sethna, NF; Shapiro, F; Sullivan, LJ; Zurakowski, D1
Dietzel, C; Filipescu, D; Fontes, ML; Hillel, Z; Hoeft, A; Juneja, R; Levin, J; Mangano, DT; Miao, Y; Ott, E; Titov, T; Tudor, IC; Vuylsteke, A1
Stief, TW1
McMurdy, N; Trudell, J1
Arellano, R; Blajchman, MA; Bussières, JS; Clinch, J; Côté, D; Duke, PC; Fergusson, DA; Fremes, S; Hébert, PC; Karski, J; MacAdams, C; Martineau, R; Mazer, CD; Murkin, JM; Pretorius, R; Robblee, JA; Rodger, M; Teoh, K; Wells, G1
Acsády, G; Selmeci, L; Seres, L; Soós, P; Székely, M1
Longstaff, C; Silva, MM; Thelwell, C; Williams, SC1
Brunskill, SJ; Doree, C; Estcourt, LJ; Murphy, MF; Stanworth, S; Trivella, M; Wardrop, D1
Beck, A; Breau, RH; Buenaventura, C; Cagiannos, I; Cowan, J; Fergusson, DA; Knoll, G; Kokolo, MB; Momoli, F; Morash, C; Niznick, N; Punjani, N; Ruzicka, M; Schachkina, S; Tinmouth, A; Xie, HY1
Brunskill, SJ; Desborough, M; Doree, C; Estcourt, LJ; Hopewell, S; Murphy, MF; Stanworth, SJ1
Byun, SY; Chae, JB; Na, JI; Park, KC1
Breau, RH; Cagiannos, I; Cnossen, S; Fergusson, DA; Fergusson, NA; Hutton, B; Lavallée, LT; Montroy, J; Morash, C1
Breau, RH; Cagiannos, I; Fergusson, DA; Flaman, A; Hutton, B; Lavallée, LT; Montroy, J; Morash, C; Tinmouth, A1
Bayter, JE; Cala, L; Cardenas-Camarena, L; Domínguez-Millan, R; Duran, H; Hoyos, AE; Lopez, A; Mogollon, IR; Perez, M; Talleri, G1

Reviews

7 review(s) available for lysine and tranexamic acid

ArticleYear
[The enzymatic linkage of fibrinogenesis and fibrinolysis (author's transl)].
    Klinische Wochenschrift, 1978, Aug-15, Volume: 56, Issue:16

    Topics: Aminocaproates; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Dexamethasone; Factor XII; Fibrin; Fibrinolysin; Fibrinolysis; Hemostasis; Humans; L Cells; Lysine; Mice; Peptide Hydrolases; Plasminogen; Plasminogen Activators; Receptors, Cell Surface; Simian virus 40; Streptokinase; Tranexamic Acid; Urokinase-Type Plasminogen Activator

1978
Aprotinin versus lysine analogues: the debate continues.
    The Annals of thoracic surgery, 1998, Volume: 65, Issue:4 Suppl

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Transfusion; Cardiac Surgical Procedures; Hemostasis, Surgical; Hemostatics; Humans; Lysine; Tranexamic Acid

1998
Current antifibrinolytic therapy for coronary artery revascularization.
    AANA journal, 2008, Volume: 76, Issue:2

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; Humans; Lysine; Patient Selection; Postoperative Hemorrhage; Risk Factors; Safety Management; Serine Proteinase Inhibitors; Tranexamic Acid; Treatment Outcome

2008
Antifibrinolytics (lysine analogues) for the prevention of bleeding in patients with haematological disorders.
    The Cochrane database of systematic reviews, 2013, Jul-29, Issue:7

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Erythrocyte Transfusion; Hematologic Diseases; Hemorrhage; Humans; Lysine; Platelet Transfusion; Thrombocytopenia; Tranexamic Acid

2013
The effects of lysine analogs during pelvic surgery: a systematic review and meta-analysis.
    Transfusion medicine reviews, 2014, Volume: 28, Issue:3

    Topics: Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Gynecologic Surgical Procedures; Hemorrhage; Humans; Lysine; Randomized Controlled Trials as Topic; Risk; Surgical Procedures, Operative; Thrombosis; Tranexamic Acid; Treatment Outcome; Urologic Surgical Procedures, Male

2014
Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disorders.
    The Cochrane database of systematic reviews, 2016, Mar-15, Volume: 3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Erythrocyte Transfusion; Hematologic Diseases; Hemorrhage; Humans; Lysine; Platelet Transfusion; Thrombocytopenia; Thromboembolism; Tranexamic Acid

2016
The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis.
    Transfusion medicine reviews, 2017, Volume: 31, Issue:3

    Topics: Adult; Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Erythrocyte Transfusion; Humans; Lysine; Neoplasms; Patient Safety; Platelet Transfusion; Randomized Controlled Trials as Topic; Tranexamic Acid; Treatment Outcome; Venous Thrombosis

2017

Trials

3 trial(s) available for lysine and tranexamic acid

ArticleYear
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; Child; Female; Fibrinolysin; Humans; Lysine; Male; Orthopedic Procedures; Plasminogen; Platelet Count; Scoliosis; Tranexamic Acid

2005
A comparison of aprotinin and lysine analogues in high-risk cardiac surgery.
    The New England journal of medicine, 2008, May-29, Volume: 358, Issue:22

    Topics: Aged; Aged, 80 and over; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Transfusion; Cardiac Surgical Procedures; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Length of Stay; Lysine; Male; Middle Aged; Postoperative Hemorrhage; Tranexamic Acid; Treatment Outcome

2008
Use of Tranexamic Acid in Liposculpture: A Double-Blind, Multicenter, Randomized Clinical Trial.
    Plastic and reconstructive surgery, 2022, 09-01, Volume: 150, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Female; Hemoglobins; Humans; Lysine; Male; Postoperative Hemorrhage; Tranexamic Acid

2022

Other Studies

29 other study(ies) available for lysine and tranexamic acid

ArticleYear
Allosteric effects of some antifibrinolytic amino acids on the catalytic activity of human plasmin.
    Biochimica et biophysica acta, 1978, Sep-11, Volume: 526, Issue:1

    Topics: Allosteric Regulation; Allosteric Site; Aminocaproic Acid; Antifibrinolytic Agents; Binding Sites; Catalysis; Enzyme Activation; Fibrinolysin; Humans; Kinetics; Lysine; Mathematics; Tranexamic Acid

1978
The effect of fibrinogen degradation products and some lysine analogues on the dissociation of plasmin(ogen)-fibrin complexes.
    Thrombosis research, 1979, Volume: 16, Issue:5-6

    Topics: Aminocaproic Acid; Animals; Cattle; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Fibrinolysis; Humans; Lysine; Plasminogen; Protein Binding; Tranexamic Acid

1979
Influence of dextran sulfate and tranexamic acid on the activation of plasminogen by urokinase.
    Thrombosis research, 1979, Volume: 16, Issue:5-6

    Topics: alpha-2-Antiplasmin; Animals; Binding Sites; Blood Coagulation; Cattle; Cyclohexanecarboxylic Acids; Dextrans; Endopeptidases; Factor XII; Fibrinolysin; Fibrinolysis; Humans; Lysine; Plasminogen Activators; Serum Globulins; Tranexamic Acid; Urokinase-Type Plasminogen Activator

1979
Effects of tranexamic acid, cis-AMCHA, and 6-aminohexanoic acid on the activation rate of plasminogen by urokinase in the presence of clot.
    Thrombosis research, 1979, Volume: 14, Issue:6

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Antifibrinolytic Agents; Blood Coagulation; Cattle; Cyclohexanecarboxylic Acids; Endopeptidases; Humans; Isomerism; Lysine; Oligopeptides; Plasminogen; Thrombin; Tranexamic Acid; Urokinase-Type Plasminogen Activator

1979
The binding of tranexamic acid to native (Glu) and modified (Lys) human plasminogen and its effect on conformation.
    The Journal of biological chemistry, 1979, Feb-25, Volume: 254, Issue:4

    Topics: Aminocaproates; Cyclohexanecarboxylic Acids; Glutamates; Humans; Kinetics; Lysine; Plasminogen; Protein Binding; Protein Conformation; Tranexamic Acid

1979
Positive co-operative binding at two weak lysine-binding sites governs the Glu-plasminogen conformational change.
    The Biochemical journal, 1992, Jul-15, Volume: 285 ( Pt 2)

    Topics: Aminocaproic Acid; Binding Sites; Fluorescence Polarization; Humans; Kinetics; Lysine; Peptide Fragments; Plasminogen; Protein Conformation; Tranexamic Acid

1992
The cationic locus on the recombinant kringle 2 domain of tissue-type plasminogen activator that stabilizes its interaction with omega-amino acids.
    Biochemistry, 1992, Dec-01, Volume: 31, Issue:47

    Topics: Amino Acid Sequence; Amino Acids; Aminocaproic Acid; Base Sequence; Binding Sites; Cations; DNA; Enzyme Stability; Escherichia coli; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Peptide Fragments; Plasmids; Recombinant Proteins; Tissue Plasminogen Activator; Tranexamic Acid

1992
Antifibrinolytic activities of alpha-N-acetyl-L-lysine methyl ester, epsilon-aminocaproic acid, and tranexamic acid. Importance of kringle interactions and active site inhibition.
    Arteriosclerosis and thrombosis : a journal of vascular biology, 1992, Volume: 12, Issue:6

    Topics: alpha-Macroglobulins; Amidohydrolases; Aminocaproic Acid; Binding Sites; Binding, Competitive; Blood Coagulation; Fibrinolysin; Fibrinolysis; Humans; Kinetics; Lysine; Peptide Fragments; Serum Globulins; Tranexamic Acid

1992
Serpin-serine protease binding kinetics: alpha 2-antiplasmin as a model inhibitor.
    Biochemistry, 1991, Jan-29, Volume: 30, Issue:4

    Topics: alpha-Macroglobulins; Aminocaproic Acid; Binding Sites; Chymotrypsin; Fibrinolysin; Humans; Kinetics; Lysine; Models, Biological; Structure-Activity Relationship; Thermodynamics; Tranexamic Acid

1991
Inhibition by tranexamic acid of the conversion of single-chain tissue plasminogen activator to its two chain form by plasmin: the presence on tissue plasminogen activator of a site to bind with lysine binding sites of plasmin.
    Thrombosis research, 1989, Sep-15, Volume: 55, Issue:6

    Topics: Animals; Binding Sites; Cyclohexanecarboxylic Acids; Electrophoresis, Polyacrylamide Gel; Fibrinolysin; Humans; Lysine; Mice; Peptide Fragments; Protein Binding; Tissue Plasminogen Activator; Tranexamic Acid

1989
Analysis of ligand-binding to the kringle 4 fragment from human plasminogen.
    European biophysics journal : EBJ, 1987, Volume: 14, Issue:6

    Topics: Aminocaproates; Benzylamines; Binding Sites; Humans; Ligands; Lysine; Magnetic Resonance Spectroscopy; Peptide Fragments; Plasminogen; Structure-Activity Relationship; Tranexamic Acid

1987
Enzymatic properties of plasmins converted from acid-treated and native Glu- and Lys-plasminogens by urokinase.
    Thrombosis research, 1981, Mar-15, Volume: 21, Issue:6

    Topics: Fibrinolysin; Glutamates; Humans; Hydrochloric Acid; Hydrolysis; Lysine; Oligopeptides; Plasminogen; Tranexamic Acid; Urokinase-Type Plasminogen Activator

1981
Secondary-site binding of Glu-plasmin, Lys-plasmin and miniplasmin to fibrin.
    The Biochemical journal, 1981, Sep-01, Volume: 197, Issue:3

    Topics: alpha-2-Antiplasmin; Binding Sites; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinolysin; Glutamates; Humans; Lysine; Peptide Fragments; Plasminogen; Protein Binding; Tranexamic Acid

1981
Fibrinolytic states in a patient with congenital deficiency of alpha 2-plasmin inhibitor.
    Blood, 1980, Volume: 55, Issue:3

    Topics: alpha-2-Antiplasmin; Antigens; Chemical Phenomena; Chemistry; Fibrin; Fibrinogen; Fibrinolysis; Glutamates; Humans; Lysine; Plasminogen; Time Factors; Tranexamic Acid; Urokinase-Type Plasminogen Activator

1980
Comparison of the lysine binding functions of lipoprotein(a) and plasminogen.
    Biochemistry, 1993, Dec-14, Volume: 32, Issue:49

    Topics: Acetylation; Amino Acid Sequence; Aminocaproic Acid; Binding Sites; Humans; Hydrogen-Ion Concentration; Iodine Radioisotopes; Kringles; Lipoprotein(a); Lysine; Molecular Sequence Data; Plasminogen; Sepharose; Sequence Homology; Structure-Activity Relationship; Tranexamic Acid

1993
Specific anionic residues of the recombinant kringle 2 domain of tissue-type plasminogen activator that are responsible for stabilization of its interaction with omega-amino acid ligands.
    Biochemistry, 1993, Apr-13, Volume: 32, Issue:14

    Topics: Amino Acid Sequence; Amino Acids; Aminocaproic Acid; Anions; Base Sequence; Binding Sites; Escherichia coli; Lysine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Peptide Fragments; Recombinant Proteins; Thermodynamics; Tissue Plasminogen Activator; Tranexamic Acid; X-Ray Diffraction

1993
Plasmin is a potent and specific chemoattractant for human peripheral monocytes acting via a cyclic guanosine monophosphate-dependent pathway.
    Blood, 1997, Jun-15, Volume: 89, Issue:12

    Topics: Alkaloids; Aminoquinolines; Benzophenanthridines; Binding Sites; Carbazoles; Chemotactic Factors; Chemotaxis; Cyclic GMP; Enzyme Inhibitors; Fibrinolysin; Glyceryl Ethers; Guanylate Cyclase; Humans; Indoles; Lysine; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organ Specificity; Pertussis Toxin; Phenanthridines; Plasminogen; Protein Kinase C; Signal Transduction; Thionucleotides; Tranexamic Acid; Urokinase-Type Plasminogen Activator; Virulence Factors, Bordetella

1997
Specificity of ligand-induced conformational change of lipoprotein(a).
    Biochemistry, 1997, Sep-23, Volume: 36, Issue:38

    Topics: Aminocaproic Acid; Glutamic Acid; Ligands; Lipoprotein(a); Lysine; Models, Chemical; Molecular Weight; Osmolar Concentration; Particle Size; Proline; Protein Conformation; Protein Denaturation; Salts; Tranexamic Acid; Ultracentrifugation

1997
Loss of cell viability dramatically elevates cell surface plasminogen binding and activation.
    Experimental cell research, 1998, Jul-10, Volume: 242, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Carboxypeptidase B; Carboxypeptidases; Cell Death; Cell Survival; Cycloheximide; Enzyme Activation; Flow Cytometry; Humans; Kinetics; Lysine; Monocytes; Plasminogen; Plasminogen Activator Inhibitor 2; Plasminogen Inactivators; Protein Synthesis Inhibitors; Tranexamic Acid; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1998
Effect of tranexamic acid and delta-aminovaleric acid on lipoprotein(a) metabolism in transgenic mice.
    Biochimica et biophysica acta, 1999, Apr-19, Volume: 1438, Issue:1

    Topics: Amino Acids; Amino Acids, Neutral; Animals; Apolipoproteins A; Cell Line; Half-Life; Lipoprotein(a); Lysine; Mice; Mice, Transgenic; Tranexamic Acid; Transfection

1999
Plasminogen binding is increased with adipocyte differentiation.
    Biochemical and biophysical research communications, 2001, Jun-08, Volume: 284, Issue:2

    Topics: 3T3 Cells; Adipocytes; Aminocaproic Acid; Animals; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Ligands; Lysine; Mice; Mice, Knockout; Plasminogen; Protein Binding; Stromal Cells; Tranexamic Acid

2001
Isolation, quantitation, and characterization of a stable complex formed by Lp[a] binding to triglyceride-rich lipoproteins.
    Journal of lipid research, 2001, Volume: 42, Issue:12

    Topics: Aminocaproic Acid; Apolipoproteins A; Arginine; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Hypertriglyceridemia; Immunoblotting; Lipoprotein(a); Lysine; Macromolecular Substances; Molecular Weight; Plasmapheresis; Proline; Protein Binding; Tranexamic Acid; Triglycerides; Ultracentrifugation

2001
Mutation E522K in human DNA topoisomerase IIbeta confers resistance to methyl N-(4'-(9-acridinylamino)-phenyl)carbamate hydrochloride and methyl N-(4'-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide but hypersensitivity to etoposide.
    Molecular pharmacology, 2004, Volume: 66, Issue:3

    Topics: Amino Acid Sequence; Amsacrine; Antineoplastic Agents; DNA; DNA Topoisomerases, Type II; Enzyme Stability; Etoposide; Glutamic Acid; Humans; Lysine; Models, Molecular; Mutation; Topoisomerase II Inhibitors; Tranexamic Acid

2004
Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery.
    JAMA, 2007, Feb-07, Volume: 297, Issue:5

    Topics: Aged; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Cardiopulmonary Bypass; Coronary Artery Bypass; Female; Follow-Up Studies; Hemostatics; Humans; Logistic Models; Lysine; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Risk; Serine Proteinase Inhibitors; Survival Analysis; Tranexamic Acid

2007
In vitro simulation of thrombolysis inhibition.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2008, Volume: 14, Issue:2

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Humans; Lysine; Tranexamic Acid

2008
Assay of oxidized fibrinogen reactivity (OFR) as a biomarker of oxidative stress in human plasma: the role of lysine analogs.
    Clinical chemistry and laboratory medicine, 2010, Volume: 48, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminocaproates; Apoprotein(a); Biomarkers; Female; Fibrinogen; Humans; Kinetics; Lysine; Male; Middle Aged; Oxidative Stress; Peripheral Vascular Diseases; Tranexamic Acid

2010
Regulation of fibrinolysis by C-terminal lysines operates through plasminogen and plasmin but not tissue-type plasminogen activator.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:11

    Topics: Binding Sites; Carboxypeptidase B; Fibrin; Fibrinolysin; Fibrinolysis; Humans; Kinetics; Kringles; Lysine; Plasminogen; Protein Binding; Protein Structure, Tertiary; Tissue Plasminogen Activator; Tranexamic Acid; Urokinase-Type Plasminogen Activator

2012
Significant improvement in crow's feet after treatment with Jet-M and a mixed solution of copper-GHK, oligo-hyaluronic acid, rhodiolar extract, tranexamic acid, and β-glucan (GHR formulation).
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2016, Volume: 18, Issue:5

    Topics: beta-Glucans; Collagen; Cosmetics; Face; Humans; Hyaluronic Acid; Lysine; Male; Middle Aged; Oligopeptides; Organometallic Compounds; Rhodiola; Skin Aging; Tranexamic Acid

2016
Lysine analogue use during cancer surgery: a survey from a Canadian tertiary care centre.
    Current oncology (Toronto, Ont.), 2020, Volume: 27, Issue:6

    Topics: Aminocaproic Acid; Blood Loss, Surgical; Humans; Lysine; Neoplasms; Ontario; Surveys and Questionnaires; Tertiary Care Centers; Tranexamic Acid

2020