lysine has been researched along with sirolimus in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 13 (61.90) | 24.3611 |
| 2020's | 4 (19.05) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YR; Demain, AL; Fang, A | 1 |
| Demain, AL; Kojima, I; Lee, MS | 1 |
| Matunis, MJ; Zhang, H; Zhu, S | 1 |
| Delrow, J; Lindstrom, KC; Parthun, MR; Tsukiyama, T; Vary, JC | 1 |
| Chen, X; Duan, Y; Wu, H; Xu, Z; Zhang, W; Zhu, X | 1 |
| Blättler, SM; Chim, H; Cunningham, JT; Gygi, SP; Haas, W; Liu, H; Puigserver, P; Romanino, K; Rüegg, MA; Shi, Y; Verdeguer, F | 1 |
| Bitto, A; Konigsberg, M; Lerner, C; Nacarelli, T; Pulliam, D; Sell, C; Torres, C; Van Remmen, H | 1 |
| Füllgrabe, J; Heldring, N; Hermanson, O; Joseph, B; Klionsky, DJ; Li, W; Lynch-Day, MA; Ma, Q; Rosenfeld, MG; Struijk, RB | 1 |
| Singh, S; Sinha, R; Srivastava, P | 1 |
| André, B; Crapeau, M; Merhi, A | 1 |
| Huang, D; Liu, H; Liu, J; Wang, B; Wen, J | 1 |
| Cruz, C; Houseley, J; Hull, RM; Jack, CV; Keller, MA; Ralser, M | 1 |
| Capanni, C; Cavallo, C; Columbaro, M; D'Apice, MR; Lattanzi, G; Murdocca, M; Pellegrini, C; Squarzoni, S | 1 |
| Dong, X; Helmbrecht, A; Loor, JJ; Saremi, B; Wang, Z; Zhou, Z | 1 |
| Dong, X; Helmbrecht, A; Loor, JJ; Saremi, B; Wang, L; Wang, Z; Zhou, Z | 1 |
| Imai, Y; Inoue, K; Kanoh, M; Kuwahara, M; Matsuda, S; Nabe, S; Suzuki, J; Takemori, A; Takemori, N; Yamada, T; Yamashita, M; Yasukawa, M | 1 |
| Chen, Y; Ding, S; Guli, A; He, J; Jin, M; Yan, C; Zhou, Z | 1 |
| Burton, JC; Capel, A; Chen, HA; Green, R; Hart, SFM; Lin, A; Lu, W; Mi, H; Rabinowitz, JD; Shou, W; Skelding, D; Subramaniam, AR; Wang, L | 1 |
| Gu, W; Kon, N; Li, H; Ou, Y; Rustgi, AK; Wang, SJ | 1 |
| de Vries, BBA; Devilee, L; Frega, M; Gabriele, M; Hommersom, M; Klein Gunnewiek, TM; Koolen, DA; Lewerissa, EI; Linda, K; Nadif Kasri, N; Oudakker, A; Schoenmaker, C; Schubert, D; Testa, G; Ulferts, E; van Bokhoven, H; Verboven, AHA | 1 |
| Bhandari, S; Cho, DH; Choe, SK; Demers, ND; Jo, DS; Kim, C; Kim, PK; Law, KB; Liao, W; McQuibban, GA; Riccio, V | 1 |
21 other study(ies) available for lysine and sirolimus
| Article | Year |
|---|---|
Effect of amino acids on rapamycin biosynthesis by Streptomyces hygroscopicus.
Topics: Amino Acids; Antifungal Agents; Culture Media; Lysine; Methionine; Phenylalanine; Pipecolic Acids; Polyenes; Quaternary Ammonium Compounds; Sirolimus; Streptomyces | 1995 |
Effect of nitrogen source on biosynthesis of rapamycin by Streptomyces hygroscopicus.
Topics: Ammonium Sulfate; Antifungal Agents; Lysine; Nitrogen; Polyenes; Sirolimus; Streptomyces | 1997 |
SUMO modification through rapamycin-mediated heterodimerization reveals a dual role for Ubc9 in targeting RanGAP1 to nuclear pore complexes.
Topics: Dimerization; GTPase-Activating Proteins; HeLa Cells; Humans; Lysine; Molecular Chaperones; Nuclear Pore; Nuclear Pore Complex Proteins; Sirolimus; SUMO-1 Protein; Transfection; Ubiquitin-Conjugating Enzymes | 2006 |
Isw1 functions in parallel with the NuA4 and Swr1 complexes in stress-induced gene repression.
Topics: Acetylation; Acetyltransferases; Adenosine Triphosphatases; Chromatin Assembly and Disassembly; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Fungal; Genome, Fungal; Histone Acetyltransferases; Histones; Lysine; Microbial Sensitivity Tests; Mutation; Promoter Regions, Genetic; Protein Transport; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Transcription Factors; Transcription, Genetic | 2006 |
Generation of high rapamycin producing strain via rational metabolic pathway-based mutagenesis and further titer improvement with fed-batch bioprocess optimization.
Topics: Fermentation; Glucose; Lysine; Metabolic Networks and Pathways; Mutagenesis; Phenylalanine; Shikimic Acid; Sirolimus; Streptomyces; Tryptophan; Ultraviolet Rays | 2010 |
Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.
Topics: Animals; Diabetes Mellitus, Experimental; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Lipid Metabolism; Liver; Lysine; Methylation; Mice; Mice, Knockout; Models, Biological; Muscle, Skeletal; Organ Specificity; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Signal Transduction; Sirolimus; YY1 Transcription Factor | 2012 |
Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts.
Topics: Adaptor Proteins, Signal Transducing; Autophagy; Biomarkers; Cellular Senescence; Fibroblasts; Gene Expression Regulation; Half-Life; Homeostasis; Humans; Lysine; Mitochondria; NF-E2-Related Factor 2; Protein Binding; Reactive Oxygen Species; Sequestosome-1 Protein; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Ubiquitin | 2013 |
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy.
Topics: Acetylation; Autophagy; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Down-Regulation; Epistasis, Genetic; Feedback, Physiological; Histone Acetyltransferases; Histones; Humans; Lysine; Sirolimus; Transcription, Genetic | 2013 |
Studies on process optimization methods for rapamycin production using Streptomyces hygroscopicus ATCC 29253.
Topics: Lysine; Models, Biological; Neural Networks, Computer; Sirolimus; Streptomyces | 2014 |
Stress conditions promote yeast Gap1 permease ubiquitylation and down-regulation via the arrestin-like Bul and Aly proteins.
Topics: 14-3-3 Proteins; Adaptor Proteins, Signal Transducing; Amino Acid Transport Systems; Amino Acids; Arrestins; Binding Sites; Down-Regulation; Lysine; Models, Biological; Models, Molecular; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Stress, Physiological; Transcription Factors; Ubiquitin-Protein Ligases; Ubiquitination | 2014 |
Comparative metabolic profiling reveals the key role of amino acids metabolism in the rapamycin overproduction by Streptomyces hygroscopicus.
Topics: Amino Acids; Biomarkers; Fermentation; Gas Chromatography-Mass Spectrometry; Hydro-Lyases; Immunosuppressive Agents; Lysine; Metabolic Networks and Pathways; Metabolomics; Mutation; Nitrogen; Real-Time Polymerase Chain Reaction; Sirolimus; Streptomyces | 2015 |
Regulation of ribosomal DNA amplification by the TOR pathway.
Topics: Acetylation; DNA, Ribosomal; Environment; Gene Amplification; Histone Deacetylases; Histones; Homologous Recombination; Lysine; Models, Biological; NAD; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Sirolimus | 2015 |
All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype.
Topics: Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Proliferation; Cells, Cultured; DNA-Binding Proteins; Drug Synergism; Fibroblasts; Gene Expression; Histones; Humans; Lamin Type A; Lysine; Membrane Proteins; Methylation; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nuclear Proteins; Phenotype; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Progeria; Reverse Transcriptase Polymerase Chain Reaction; Sirolimus; Tretinoin | 2015 |
Varying the ratio of Lys:Met while maintaining the ratios of Thr:Phe, Lys:Thr, Lys:His, and Lys:Val alters mammary cellular metabolites, mammalian target of rapamycin signaling, and gene transcription.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acids; Animals; Caseins; Cattle; Epithelial Cells; Female; Histidine; Lactation; Lysine; Mammary Glands, Animal; Milk; Milk Proteins; Phenylalanine; Phosphorylation; Protein Biosynthesis; Signal Transduction; Sirolimus; Threonine; TOR Serine-Threonine Kinases; Transcription, Genetic; Valine | 2018 |
Increasing the availability of threonine, isoleucine, valine, and leucine relative to lysine while maintaining an ideal ratio of lysine:methionine alters mammary cellular metabolites, mammalian target of rapamycin signaling, and gene transcription.
Topics: Amino Acid Sequence; Animals; Cattle; Female; Isoleucine; Leucine; Lysine; Mammary Glands, Animal; Methionine; Peptide Fragments; Sirolimus; Threonine; Transcription, Genetic; Valine | 2018 |
The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation.
Topics: Activation, Metabolic; Animals; Carbon; CD8-Positive T-Lymphocytes; Cell Proliferation; Female; Glutamine; Histones; Ketoglutaric Acids; Lymphocyte Activation; Lysine; Mechanistic Target of Rapamycin Complex 1; Metabolomics; Methylation; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins; Sirolimus | 2018 |
Comprehensive Analysis of Lysine Acetylome Reveals a Site-Specific Pattern in Rapamycin-Induced Autophagy.
Topics: Acetylation; Autophagy; Binding Sites; Humans; Isotope Labeling; Lysine; Protein Processing, Post-Translational; Proteomics; Sirolimus; Tandem Mass Spectrometry | 2019 |
Metabolic excretion associated with nutrient-growth dysregulation promotes the rapid evolution of an overt metabolic defect.
Topics: Adaptation, Physiological; Autophagy; Biological Evolution; Glucose; Lysine; Metabolic Networks and Pathways; Nitrogen; Nutrients; Ribosomes; Saccharomyces cerevisiae; Sirolimus; Stress, Physiological | 2020 |
mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression.
Topics: Acetylation; Animals; Carcinogenesis; Cell Cycle Checkpoints; Embryo, Mammalian; Lysine; Mice; Mutation; Neoplasms; Proto-Oncogene Proteins c-mdm2; Sirolimus; Survival Analysis; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2021 |
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders.
Topics: Abnormalities, Multiple; Autophagosomes; Autophagy; Chromosome Deletion; Chromosomes, Human, Pair 17; Epigenesis, Genetic; Humans; Intellectual Disability; Lysine; Lysosomes; Reactive Oxygen Species; Sirolimus; Superoxide Dismutase-1; TOR Serine-Threonine Kinases | 2022 |
PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS.
Topics: Actins; Amino Acids; Animals; Autophagy; Fibroblasts; Humans; Leucine; Lysine; Macroautophagy; Membrane Proteins; Mice; Oxygen; Peroxisomes; Reactive Oxygen Species; Sirolimus; Ubiquitin; Zebrafish | 2023 |