Page last updated: 2024-08-17

lysine and s-adenosylmethionine

lysine has been researched along with s-adenosylmethionine in 85 studies

Research

Studies (85)

Timeframe	Studies, this research(%)	All Research%
pre-1990	34 (40.00)	18.7374
1990's	2 (2.35)	18.2507
2000's	17 (20.00)	29.6817
2010's	25 (29.41)	24.3611
2020's	7 (8.24)	2.80

Authors

Authors	Studies
Baena, RM; Bayés, R; Campoy, C; Goicoechea, A; López, C; Molina-Font, JA; Pedrosa, T; Peinado, JM; Rivero, M	1
Caldez, MJ; Choi, H; Coppola, V; Eisenhaber, F; Goh, CMF; Gopinathan, L; Jones, OS; Kaldis, P; Kanagasundaram, Y; Kien, YL; Kurochkin, IV; Low, KN; Maurer-Stroh, S; Niska-Blakie, J; Ong, CB; Pfeiffenberger, E; Tessarollo, L	1
Borum, PR; Broquist, HP	1
Baxter, CS; Byvoet, P; Sayre, DF	1
Kim, S; Paik, WK	3
Huszar, G	2
Baraniak, J; Frey, PA; Moss, ML	1
Amidei, K; Barber, M; Byvoet, P; Lowell, N; Trudeau, W	1
Frey, PA; Moss, M	1
Munro, HN; Roel, LE; Weiss, BF; Wurtman, RJ	1
Nakamura, KD; Schlenk, F	1
Baxter, CS; Byvoet, P	1
Edgar, DH; Hope, DB	1
Dudock, B; Michael, M; Roe, B	1
Cox, GS; Kaback, HR; Weissbach, H	1
Fillingame, RH; Morris, DR	1
Kakimoto, Y; Miyake, M	1
Borun, TW; Lee, HW; Paik, WK	1
Benditt, M; Kim, S; Paik, WK	1
Greenaway, PJ; Levine, D	1
Burdon, RH; Garven, EV	1
Kakimoto, Y	1
Brush, A; Paulus, H	1
Ayala, F; Zappia, V	1
Lee, HW; Paik, WK	1
Kim, S; Lee, HW; Paik, WK	1
Gallwitz, D	1
Krzysik, B; McManus, I; Vergnes, JP	1
Burdon, RH	1
Lea, PJ; Miflin, BJ; Rognes, SE	1
Allfrey, VG; Boffa, LC; Gruss, RJ	1
Bright, SW; Miflin, BJ; Rognes, SE	1
Curien, G; Douce, R; Dumas, R; Ravanel, S	1
Beinert, H; Booker, S; Frey, PA; Lieder, KW; Reed, GH; Ruzicka, FJ	1
Bandarian, V; Booker, S; Frey, PA; Lieder, KW; Reed, GH; Wu, W	1
Allis, CD; Briggs, SD; Erdjument-Bromage, H; Feng, Q; Huang, ZQ; Strahl, BD; Tempst, P; Wang, H; Wong, J; Xia, L; Zhang, Y	1
Amir, R; Avraham, T; Hacham, Y	1
Ballinger, MD; Chang, CH; Frey, PA; Reed, GH	1
Chang, JH; Cho, Y; Joachimiak, A; Kim, YC; Kwak, E; Kwon, T; Lee, CW; Lee, J	1
Farooq, A; Koch, AW; Manzur, KL; Plotnikova, O; Zeng, L; Zhou, MM	1
Broderick, JB; Broderick, WE; Cosper, MM; Cosper, NJ; Hong, W; Johnson, MK; Scott, RA; Shokes, JE	1
Eliot, AC; Famm, K; Kirsch, JF; Sandmark, J; Schneider, G	1
Bedford, MT; Cheng, D; King, RW; Swanson, MS; Weinstein, EJ; Yadav, N	1
Chatterjee, NP; Howitt, CL; Luan, L; Perkins, JB; Pero, JG; Van Arsdell, SW; Yocum, RR	1
Chin, HG; Estève, PO; Jacobsen, SE; Patnaik, D; Pradhan, S	1
Endo, Y; Fukai, S; Hori, H; Nureki, O; Watanabe, K	1
Curien, G; Dumas, R; Laurencin, M; Robert-Genthon, M	1
Góralska, M; Somogyi, E; Srebro, Z; Sura, P; Wiliński, B; Wiliński, J	1
Bruice, TC; Zhang, X	2
Baird, NJ; Ferré-D'Amaré, AR	1
Banerjee, R; Kabil, O; Koutmos, M; Smith, JL	1
Basrur, V; Cao, F; Chen, Y; Cierpicki, T; Dou, Y; Lei, M; Liu, Y	1
Bertozzi, CR; Binda, O; Boyce, M; Gozani, O; Palaniappan, KK; Rush, JS	1
Bai, Q; Du, Y; Hai, J; Hu, T; Jin, N; Shen, Y; Wang, F; Wang, Q; Yang, J; Yao, X	1
Kim, S; Kim, YS; Lou, MF; Paik, MK; Paik, WK	1
Bardag-Gorce, F; Buslon, V; French, BA; French, SW; Li, J; Oliva, J; Zhong, J	1
Bryk, M; Henderson Pozzi, M; Jordan, RA; Mueller, JE; Schneider, V; Williamson, K	1
Dillon, MB; Mowen, KA; Rust, HL; Thompson, PR	1
Dahl, HA; Falnes, PØ; Ho, AY; Małecki, J; Moen, A	1
Clarke, SG; Dzialo, MC; Loo, JA; Shen, S; Travaglini, KJ	1
Battle, SL; Bielas, JH; Blau, CA; Detraux, D; Devi, A; Ericson, NG; Ferreccio, A; Fiehn, O; Fischer, KA; Gu, H; Hawkins, RD; Hesson, J; Hockenbery, D; Margaretha, L; Margineantu, D; Margolin, AA; Mathieu, J; Moon, RT; Raftery, D; Robitaille, AM; Ruohola-Baker, H; Showalter, M; Sperber, H; Valensisi, C; Wang, Y; Ware, CB; Xu, Z	1
Albertí, S; Conn, GL; Dammer, EB; Duong, DM; Goldberg, JB; Kuiper, EG; Meisner, J; Owings, JP; Prezioso, SM; Seyfried, NT; Varga, JJ; Zelinskaya, N	1
Allis, CD; Bellon, S; Cantone, N; Cummings, R; Hoelper, D; Jain, SU; Jayaram, H; Lewis, PW; Lundgren, SM; Poy, F	1
Bischof, S; Cokus, SJ; Díaz de la Garza, RI; Feng, S; Garcia-Salinas, C; Groth, M; Hale, CJ; Hell, R; Jacobsen, SE; John, A; Long, JA; Moissiard, G; Ramos-Parra, PA; Smith, DC; Wang, H; Wirtz, M; Zhai, J	1
Chen, Y; Chu, Y; Deng, H; Huang, L; Li, W; Liu, D; Liu, ZJ; Ma, J; Ouyang, S; Wang, T; Zhang, Z; Zhu, Y	1
Blum, G; Bothwell, IR; Kapilashrami, K; Linscott, JA; Luo, M; Senevirathne, C; Wang, Z	1
Schramma, KR; Seyedsayamdost, MR	1
Kuang, Z; Sutter, BM; Tu, BP; Wang, Y; Ye, C	1
Bratkowski, M; Liu, X; Yang, X	1
Abhishek, S; Nakarakanti, NK; Nivya, MA; Rajakumara, E; Satish, M; Shivani, D; Vani, MV	1
Guo, H; Mecinović, J; Qian, P; Reddy, YV; Temimi, AHKA; White, PB	1
Galili, G; Wang, G; Wang, W; Xu, M	1
Bitton, R; Feldman, M; Kublanovsky, M; Levy, D; Morgenstern, D; Shmidov, Y; Weil, LE	1
Chen, S; Kapilashrami, K; Linscott, JA; Luo, M; Senevirathne, C; Wang, J; Wang, Z	1
Ando, K; Hirata, A; Hiura, K; Hori, H; Kawamura, T; Nakada, S; Nomura, Y; Ogino, H; Ohno, S; Oka, N; Yasuda, A; Yokogawa, T	1
Balo, AR; Britt, RD; Caruso, A; Seyedsayamdost, MR; Tantillo, DJ; Tao, L	1
Baabe, D; Bröring, M; Burghaus, O; Gutsmann, T; Hurwitz, R; Kolbe, M; Nehls, C; Wang, C	1
Breaker, RR	1
Kamezawa, M; Kitano, A; Kojima-Yuasa, A; Matsui-Yuasa, I; Norikura, T; Shimakawa, H	1
Dong, H; Huang, X; Li, B; Li, H; Li, J; Shi, Q; Wang, Y; Wang, Z; Yang, H; Zhang, Y; Zheng, J	1
Francis, JW; Gozani, O; Lu, J; Narkhede, P; Shao, Z; Song, J; Trinh, AT	1

Reviews

3 review(s) available for lysine and s-adenosylmethionine

Article	Year
Protein methylation: chemical, enzymological, and biological significance. Advances in enzymology and related areas of molecular biology, 1975, Volume: 42 Topics: Amino Acids; Animals; Arginine; Cations, Divalent; Chloramphenicol; DNA; Glycine; Humans; Kinetics; Liver; Lysine; Methionine; Methyltransferases; Molecular Weight; Organ Specificity; Proteins; Rats; S-Adenosylmethionine; Species Specificity; Tetrahymena; Thymus Gland; Time Factors; tRNA Methyltransferases	1975
Regulation of amino acid decarboxylation. Annual review of biochemistry, 1974, Volume: 43, Issue:0 Topics: Amino Acids; Animals; Arginine; Biogenic Amines; Carboxy-Lyases; Diamines; Enzyme Activation; Escherichia coli; Glutamates; Histidine; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Lysine; Organ Specificity; Ornithine; Pimelic Acids; Putrescine; S-Adenosylmethionine; Spermidine; Spermine	1974
New insights into the metabolism of aspartate-family amino acids in plant seeds. Plant reproduction, 2018, Volume: 31, Issue:3 Topics: Amino Acids; Aspartic Acid; Gene Expression Regulation, Plant; Lysine; Methionine; S-Adenosylmethionine; Seeds	2018

Other Studies

82 other study(ies) available for lysine and s-adenosylmethionine

Article	Year
Role of intrapartum hypoxia in carnitine nutritional status during the early neonatal period. Early human development, 2001, Volume: 65 Suppl Topics: Carnitine; Chromatography, High Pressure Liquid; Esters; Fetal Hypoxia; Gestational Age; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Lysine; Methionine; Nutritional Status	2001
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype. Cellular and molecular life sciences : CMLS, 2020, Volume: 77, Issue:17 Topics: Aging; Animals; Anti-Bacterial Agents; Bacteria; Carnitine; Coenzyme A-Transferases; Dietary Supplements; Feces; Gastrointestinal Microbiome; Humans; Kidney; Lipid Metabolism; Liver; Lysine; Metabolic Syndrome; Metabolome; Mice; Mice, Knockout; Obesity; Tryptophan	2020
Purification of S-adenosylmethionine: epsilon-N-L-lysine methyltransferase. The first enzyme in carnitine biosynthesis. The Journal of biological chemistry, 1977, Aug-25, Volume: 252, Issue:16 Topics: Amino Acids; Carnitine; Lysine; Methyltransferases; Molecular Weight; Neurospora crassa; S-Adenosylmethionine; Spectrophotometry; Spectrophotometry, Ultraviolet	1977
Displacement and aberrant methylation in vitro of H-1 histone in rat liver nuclei after half-saturation of chromatin with polycations. Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:12 Topics: Animals; Cations; Cell Nucleus; Chromatin; Histones; Lysine; Methylation; Methyltransferases; Polylysine; Protamines; Rats; S-Adenosylmethionine; Spermidine	1978
Tissue-specific biosynthesis of epsilon-N-monomethyllysine and epsilon-N-trimethyllysine in skeletal and cardiac muscle myosin: a model for the cell-free study of post-translational amino acid modifications in proteins. Journal of molecular biology, 1975, May-25, Volume: 94, Issue:3 Topics: Animals; Chick Embryo; Chickens; Cytosol; Lysine; Methylation; Methyltransferases; Muscles; Myocardium; Myosins; Organ Specificity; Polyribosomes; Protein Biosynthesis; S-Adenosylmethionine	1975
Lysine 2,3-aminomutase. Support for a mechanism of hydrogen transfer involving S-adenosylmethionine. The Journal of biological chemistry, 1989, Jan-25, Volume: 264, Issue:3 Topics: Amino Acid Isomerases; Hydrogen; Intramolecular Transferases; Lysine; Models, Chemical; S-Adenosylmethionine	1989
Effect of exogenous histone H5 on integration of histone H1 in rat liver chromatin. Correlations with aberrant epsilon-N-methylation of histone H1. Biochimica et biophysica acta, 1986, Jun-20, Volume: 867, Issue:3 Topics: Animals; Binding Sites; Chickens; Chromatin; Histones; Liver; Lysine; Methylation; Methyltransferases; Nucleosomes; Polylysine; Rats; S-Adenosylmethionine; Salmine	1986
The role of S-adenosylmethionine in the lysine 2,3-aminomutase reaction. The Journal of biological chemistry, 1987, Nov-05, Volume: 262, Issue:31 Topics: Amino Acid Isomerases; Clostridium; Intramolecular Transferases; Kinetics; Lysine; S-Adenosylmethionine; Tritium	1987
The effect of L-DOPA on brain polysomes and protein synthesis: probable mediation by intracellular dopamine. Advances in neurology, 1974, Volume: 5 Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbon Radioisotopes; Decarboxylation; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Enzyme Inhibitors; Hydrazines; Leucine; Levodopa; Lysine; Male; Methyldopa; Nerve Tissue Proteins; Norepinephrine; Polyribosomes; Rats; S-Adenosylmethionine; Time Factors	1974
Examination of isolated yeast cell vacuoles for active transport. Journal of bacteriology, 1974, Volume: 118, Issue:1 Topics: Arginine; Biological Transport, Active; Candida; Carbon Radioisotopes; Inclusion Bodies; Lysine; Methionine; Microscopy, Ultraviolet; S-Adenosylmethionine; Stereoisomerism; Uric Acid	1974
Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase. Cancer research, 1974, Volume: 34, Issue:6 Topics: Adenosine; Animals; Azo Compounds; Benz(a)Anthracenes; Carbon Radioisotopes; Carcinogens; Cell Nucleus; Dimethylformamide; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Lysine; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine	1974
Neurophysin methylation in extracts of bovine posterior pituitary gland: hormone binding ability. FEBS letters, 1974, Dec-15, Volume: 49, Issue:2 Topics: Animals; Binding Sites; Carbon Radioisotopes; Cattle; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kinetics; Lysine; Methylation; Molecular Weight; Neurophysins; Pituitary Gland, Posterior; Protein Binding; Receptors, Cell Surface; S-Adenosylmethionine; Vasopressins	1974
Function of N2 methylguanine in phenylalanine transfer RNA. Nature: New biology, 1973, Dec-05, Volume: 246, Issue:153 Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Base Sequence; Binding Sites; Escherichia coli; Guanine; In Vitro Techniques; Isoleucine; Kinetics; Liver; Lysine; Methionine; Methylation; Nucleic Acid Conformation; Phenylalanine; Rabbits; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Triticum; tRNA Methyltransferases; Valine	1973
Defective transport in S-adenosylmethionine synthetase mutants of Escherichia coli. Archives of biochemistry and biophysics, 1974, Apr-02, Volume: 161, Issue:2 Topics: Adenosine Triphosphate; Amino Acids; Biological Transport; Carbon Radioisotopes; Cell Membrane; Chromatography, Gas; Escherichia coli; Fatty Acids; Glucose; Kinetics; Leucine; Lysine; Methionine; Methylglycosides; Mutation; Organoids; S-Adenosylmethionine; Species Specificity; Time Factors; Transferases; Tritium	1974
Protein methylation by cerebral tissue. Journal of neurochemistry, 1973, Volume: 20, Issue:3 Topics: Acetone; Amino Acids; Ammonium Sulfate; Animals; Arginine; Brain; Carbon Isotopes; Cattle; Chromatography, DEAE-Cellulose; Cytoplasm; Dialysis; Histones; Lysine; Methylation; Nerve Tissue Proteins; Powders; Proteins; Rats; S-Adenosylmethionine; Time Factors	1973
The periodic synthesis of S-adenosylmethionine: protein methyltransferases during the HeLa S-3 cell cycle. The Journal of biological chemistry, 1973, Jun-25, Volume: 248, Issue:12 Topics: Amino Acids; Arginine; Carbon Isotopes; Cycloheximide; Cytarabine; Dactinomycin; DNA Replication; DNA, Neoplasm; HeLa Cells; Histones; Humans; Kinetics; Lysine; Methionine; Methylation; Methyltransferases; Mitosis; Neoplasm Proteins; S-Adenosylmethionine; Thymidine	1973
Protein methylase 3 of rat kidney during the early development. FEBS letters, 1973, Sep-15, Volume: 35, Issue:2 Topics: Aging; Animals; Carbon Radioisotopes; Cell Nucleus; DNA; Female; Fetus; Kidney; Lysine; Methyltransferases; Pregnancy; Proteins; Rats; S-Adenosylmethionine	1973
Protein methylases during the development of rat brain. Biochimica et biophysica acta, 1973, Jun-20, Volume: 313, Issue:1 Topics: Aging; Animals; Body Weight; Brain; Carbon Radioisotopes; Cell Nucleus; Cerebellum; Cytosol; Liver; Lysine; Medulla Oblongata; Mesencephalon; Methionine; Methyltransferases; Mice; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; S-Adenosylmethionine; Subcellular Fractions; Tritium	1973
Identification of a soluble protein methylase in chicken embryo nuclei. Biochimica et biophysica acta, 1974, Jun-18, Volume: 350, Issue:2 Topics: Animals; Cattle; Cell Nucleus; Chick Embryo; Chromatography, Ion Exchange; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Histones; Hydrogen-Ion Concentration; Kinetics; Lysine; Magnesium; Methyltransferases; Proteins; S-Adenosylmethionine; Solubility; Spectrophotometry, Ultraviolet; Thymus Gland; Tritium; Ultrasonics	1974
Enzymic modification of chromosomal macromolecules. II. The formation of histone epsilon-N-trimethyl-L-lysine by a soluble chromatin methylase. Biochimica et biophysica acta, 1971, Mar-11, Volume: 232, Issue:2 Topics: Animals; Arginine; Ascitic Fluid; Buffers; Carbon Isotopes; Cattle; Chemical Precipitation; Chromatography, Paper; Chromosomes; Dialysis; Drug Stability; Edetic Acid; Ethionine; Histones; Hydrogen-Ion Concentration; Lysine; Mercaptoethanol; Methyltransferases; Mice; Neoplasm Proteins; Neoplasms, Experimental; S-Adenosylmethionine; Sodium Chloride; Solubility; Temperature; Thymus Gland; Time Factors; Transferases; Trichloroacetic Acid; Tritium	1971
Methylation of arginine and lysine residues of cerebral proteins. Biochimica et biophysica acta, 1971, Jul-25, Volume: 243, Issue:1 Topics: Amino Acids; Animals; Arginine; Bacteria; Brain; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Enterococcus faecalis; Hydrolysis; Isomerism; Liver; Lysine; Methylation; Nerve Tissue Proteins; Proteins; Rats; S-Adenosylmethionine; Ureohydrolases	1971
The enzymic formation of O-acetylhomoserine in Bacillus subtilis and its regulation by methionine and S-adenosylmethionine. Biochemical and biophysical research communications, 1971, Nov-05, Volume: 45, Issue:3 Topics: Acetates; Acylation; Adenosine; Amino Acids; Bacillus subtilis; Carbon Isotopes; Cell-Free System; Cells, Cultured; Coenzyme A; Depression, Chemical; Escherichia coli; Feedback; Homoserine; Hydroxybutyrates; Lysine; Methionine; S-Adenosylmethionine; Succinates	1971
Studies on the activation of lysine-2,3-aminomutase by (-)-S-adenosyl-L-methionine. Biochimica et biophysica acta, 1972, May-12, Volume: 268, Issue:2 Topics: Adenosine; Butyrates; Carbon Isotopes; Chromatography, Thin Layer; Clostridium; Dialysis; Electrophoresis, Paper; Enzyme Activation; Isomerases; Kinetics; Lysine; Methionine; Propylamines; Protein Binding; S-Adenosylmethionine; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship; Trichloroacetic Acid; Ultraviolet Rays	1972
Histone methylation during hepatic regeneration in rat. Biochimica et biophysica acta, 1972, Aug-16, Volume: 277, Issue:1 Topics: Animals; Arginine; Carbon Isotopes; Cytoplasm; DNA; Hepatectomy; Histones; Kinetics; Liver; Liver Regeneration; Lysine; Male; Methylation; Methyltransferases; Orotic Acid; Proteins; Rats; RNA; S-Adenosylmethionine; Thymidine; Tritium	1972
Protein methylation during the development of rat brain. Biochemical and biophysical research communications, 1972, Jan-31, Volume: 46, Issue:2 Topics: Animals; Animals, Newborn; Arginine; Brain; Carbon Isotopes; Carboxylic Acids; Cytoplasm; Ethanol; Fetus; Histones; Lysine; Methionine; Methylation; Methyltransferases; Nerve Tissue Proteins; Proteins; Rats; S-Adenosylmethionine; Solubility; Sulfuric Acids; Transferases; Tritium	1972
Protein methylation. Science (New York, N.Y.), 1971, Oct-08, Volume: 174, Issue:4005 Topics: Actins; Amino Acids; Animals; Arginine; Aspartic Acid; Autoanalysis; Carboxylic Acids; Cats; Cattle; Cell Wall; Chromatography, Paper; Cytochromes; Flagella; Glutamates; Histidine; Histones; Humans; Lysine; Methylation; Methyltransferases; Myosins; Ornithine; Ovalbumin; Proteins; Rabbits; Rats; Ribosomes; S-Adenosylmethionine	1971
Histone methylation. Partial purification of two histone-specific methyltransferases from rat thymus nuclei preferentially methylating histones F2a 1 and F3. Archives of biochemistry and biophysics, 1971, Volume: 145, Issue:2 Topics: Acetone; Albumins; Amino Acids; Ammonium Sulfate; Animals; Arginine; Cell Nucleus; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytochromes; Electrophoresis; Hemoglobins; Histidine; Histones; Hydrogen-Ion Concentration; Kinetics; Lysine; Male; Methylation; Methyltransferases; Molecular Weight; Muramidase; Peptides; Protamines; Rats; Rats, Inbred Strains; Ribonucleases; S-Adenosylmethionine; Thymus Gland; Tritium	1971
Enzymatic methylation of skeletal muscle contractile proteins. Archives of biochemistry and biophysics, 1971, Volume: 146, Issue:1 Topics: Actins; Actomyosin; Animals; Animals, Newborn; Carbon Isotopes; Chick Embryo; Chickens; Chromatography, Gel; Chromatography, Ion Exchange; Histidine; Kinetics; Lysine; Methionine; Methylation; Muscle Proteins; Muscles; Myofibrils; Myosins; S-Adenosylmethionine; Sarcoplasmic Reticulum; Ultracentrifugation	1971
Enzymic modification of chromosomal macromolecules. I. DNA and protein methylation in mouse tumour cell chromatin. Biochimica et biophysica acta, 1971, Mar-11, Volume: 232, Issue:2 Topics: Amino Acids; Animals; Arginine; Ascitic Fluid; Catalysis; Cell Nucleus; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography; Chromatography, Paper; Chromosomes; Colorimetry; Cytosine; Deoxyribonucleases; DNA, Neoplasm; Drug Stability; Electrophoresis; Histidine; Histones; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Methylation; Methyltransferases; Mice; Neoplasm Proteins; Neoplasms, Experimental; S-Adenosylmethionine; Temperature; Time Factors; Transferases; Tritium	1971
S-adenosylmethionine--a novel regulator of aspartate kinase. Nature, 1980, Sep-25, Volume: 287, Issue:5780 Topics: Aspartate Kinase; Binding Sites; Drug Synergism; Lysine; Phosphotransferases; Plants; S-Adenosylmethionine	1980
Manifold effects of sodium butyrate on nuclear function. Selective and reversible inhibition of phosphorylation of histones H1 and H2A and impaired methylation of lysine and arginine residues in nuclear protein fractions. The Journal of biological chemistry, 1981, Sep-25, Volume: 256, Issue:18 Topics: Arginine; Butyrates; Cell Nucleus; HeLa Cells; Histones; Humans; Lysine; Methylation; Nucleoproteins; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Protein Kinases; S-Adenosylmethionine	1981
Threonine accumulation in the seeds of a barley mutant with an altered aspartate kinase. Biochemical genetics, 1982, Volume: 20, Issue:3-4 Topics: Amino Acids; Aspartate Kinase; Edible Grain; Genes, Dominant; Hordeum; Isoenzymes; Lysine; Mutation; Phosphotransferases; S-Adenosylmethionine; Seeds; Threonine	1982
Methylated lysines and 3-methylhistidine in myosin: tissue and developmental differences. Methods in enzymology, 1984, Volume: 106 Topics: Amino Acid Sequence; Amino Acids; Animals; Chick Embryo; Histidine; Lysine; Methylation; Methylhistidines; Muscles; Myocardium; Myosins; Plants; Polyribosomes; Rabbits; Radioisotope Dilution Technique; S-Adenosylmethionine; Triticum; Tritium	1984
Characterization of an Arabidopsis thaliana cDNA encoding an S-adenosylmethionine-sensitive threonine synthase. Threonine synthase from higher plants. FEBS letters, 1996, Jul-15, Volume: 390, Issue:1 Topics: Amino Acid Sequence; Arabidopsis; Base Sequence; Carbon-Oxygen Lyases; Chromatography, Gel; Chromatography, Ion Exchange; Cloning, Molecular; Conserved Sequence; DNA Primers; DNA, Complementary; Escherichia coli; Kinetics; Lyases; Lysine; Molecular Sequence Data; Polymerase Chain Reaction; Recombinant Proteins; S-Adenosylmethionine; Sequence Homology, Amino Acid	1996
S-Adenosylmethionine-dependent reduction of lysine 2,3-aminomutase and observation of the catalytically functional iron-sulfur centers by electron paramagnetic resonance. Biochemistry, 1998, Feb-24, Volume: 37, Issue:8 Topics: Binding Sites; Catalysis; Clostridium; Cobalt; Dithionite; Electron Spin Resonance Spectroscopy; Free Radicals; Intramolecular Transferases; Iron; Lysine; Oxidation-Reduction; Photochemistry; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur	1998
Lysine 2,3-aminomutase and trans-4,5-dehydrolysine: characterization of an allylic analogue of a substrate-based radical in the catalytic mechanism. Biochemistry, 2000, Aug-08, Volume: 39, Issue:31 Topics: Binding Sites; Catalysis; Clostridium; Deuterium; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Enzyme Stability; Free Radicals; Hydrolysis; Intramolecular Transferases; Lysine; Molecular Conformation; S-Adenosylmethionine; Substrate Specificity	2000
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. Science (New York, N.Y.), 2001, Aug-03, Volume: 293, Issue:5531 Topics: Acetylation; Amino Acid Sequence; Animals; Arginine; Binding Sites; Cell Nucleus; HeLa Cells; Histones; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Lysine; Methylation; Methyltransferases; Molecular Sequence Data; Mutation; Oocytes; Protein-Arginine N-Methyltransferases; Receptors, Androgen; Recombinant Proteins; S-Adenosylmethionine; Transcriptional Activation; Xenopus	2001
The N-terminal region of Arabidopsis cystathionine gamma-synthase plays an important regulatory role in methionine metabolism. Plant physiology, 2002, Volume: 128, Issue:2 Topics: Arabidopsis; Aspartic Acid; Carbon-Oxygen Lyases; Escherichia coli; Ethylenes; Gene Expression Regulation, Enzymologic; Genetic Complementation Test; Isoleucine; Lysine; Methionine; Mutation; Nicotiana; Phenotype; Plant Shoots; Plants, Genetically Modified; S-Adenosylmethionine; Threonine; Vitamin U	2002
Kinetic characterization of transient free radical intermediates in reaction of lysine 2,3-aminomutase by EPR lineshape analysis. Methods in enzymology, 2002, Volume: 354 Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Intramolecular Transferases; Lysine; Metalloproteins; Molecular Structure; S-Adenosylmethionine	2002
Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet. The EMBO journal, 2003, Jan-15, Volume: 22, Issue:2 Topics: Amino Acid Sequence; Animals; Binding Sites; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Protein Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Sequence Alignment	2003
A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3. Nature structural biology, 2003, Volume: 10, Issue:3 Topics: Amino Acid Sequence; Animals; Binding Sites; Dimerization; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutagenesis; Paramecium; Phycodnaviridae; Protein Conformation; Protein Methyltransferases; Protein Structure, Tertiary; S-Adenosylmethionine; Sequence Homology, Amino Acid; Structural Homology, Protein; Substrate Specificity; Viral Proteins	2003
Structural studies of the interaction of S-adenosylmethionine with the [4Fe-4S] clusters in biotin synthase and pyruvate formate-lyase activating enzyme. Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:7 Topics: Acetyltransferases; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Coenzymes; Enzyme Activation; Enzymes; Escherichia coli Proteins; Iron; Iron-Sulfur Proteins; Lysine; Methionine; Multienzyme Complexes; S-Adenosylmethionine; Spectrometry, X-Ray Emission; Spectrum Analysis; Substrate Specificity; Sulfurtransferases	2003
Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. Biochemistry, 2004, Feb-10, Volume: 43, Issue:5 Topics: Alanine; Amination; Amino Acids, Diamino; Arginine; Binding Sites; Catalysis; Conserved Sequence; Crystallography, X-Ray; Escherichia coli Proteins; Glutamine; Kinetics; Lysine; Mutagenesis, Site-Directed; S-Adenosylmethionine; Substrate Specificity; Transaminases; Tyrosine	2004
Small molecule regulators of protein arginine methyltransferases. The Journal of biological chemistry, 2004, Jun-04, Volume: 279, Issue:23 Topics: Arginine; Binding Sites; Cell Line, Tumor; Cell Nucleus; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Epitopes; Genes, Reporter; Glutathione Transferase; Green Fluorescent Proteins; Humans; Inhibitory Concentration 50; Light; Luciferases; Luminescent Proteins; Lysine; Methylation; Models, Chemical; Nitrogen; Plasmids; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Transport; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Transfection; Ultraviolet Rays	2004
Removing a bottleneck in the Bacillus subtilis biotin pathway: bioA utilizes lysine rather than S-adenosylmethionine as the amino donor in the KAPA-to-DAPA reaction. Biotechnology and bioengineering, 2005, Jul-05, Volume: 91, Issue:1 Topics: Amino Acids; Amino Acids, Diamino; Bacillus subtilis; Bacterial Proteins; Biotin; Gene Expression Regulation, Bacterial; Lysine; Protein Engineering; Recombinant Proteins; S-Adenosylmethionine; Signal Transduction; Transaminases	2005
Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis. Biochemistry, 2006, Mar-14, Volume: 45, Issue:10 Topics: Amino Acid Sequence; Animals; Baculoviridae; Catalytic Domain; Cell Line; Chromatin; Coenzymes; Dose-Response Relationship, Drug; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Methyltransferases; Models, Biological; Molecular Sequence Data; Peptides; Protein Methyltransferases; Recombinant Proteins; Repressor Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Spodoptera; Substrate Specificity; Time Factors	2006
Functional categorization of the conserved basic amino acid residues in TrmH (tRNA (Gm18) methyltransferase) enzymes. The Journal of biological chemistry, 2006, Nov-10, Volume: 281, Issue:45 Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; Catalysis; Catalytic Domain; Chromatography, Affinity; Chromatography, Gel; Conserved Sequence; Electrophoretic Mobility Shift Assay; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; RNA, Transfer; S-Adenosylmethionine; Sequence Homology, Amino Acid; tRNA Methyltransferases	2006
Allosteric monofunctional aspartate kinases from Arabidopsis. The FEBS journal, 2007, Volume: 274, Issue:1 Topics: Allosteric Regulation; Arabidopsis; Arabidopsis Proteins; Aspartate Kinase; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Kinetics; Lysine; Protein Isoforms; Recombinant Proteins; S-Adenosylmethionine	2007
Aspirin augments the concentration of endogenous hydrogen sulfide in mouse brain and liver. Folia medica Cracoviensia, 2006, Volume: 47, Issue:1-4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Brain Chemistry; Female; Humans; Hydrogen Sulfide; Liver; Lysine; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; S-Adenosylmethionine; Sex Factors	2006
Enzymatic mechanism and product specificity of SET-domain protein lysine methyltransferases. Proceedings of the National Academy of Sciences of the United States of America, 2008, Apr-15, Volume: 105, Issue:15 Topics: Chromatin; Histone-Lysine N-Methyltransferase; Lysine; Methylation; Models, Molecular; Quantum Theory; S-Adenosylhomocysteine; S-Adenosylmethionine	2008
Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8. Biochemistry, 2008, Jun-24, Volume: 47, Issue:25 Topics: Catalysis; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Quantum Theory; S-Adenosylhomocysteine; S-Adenosylmethionine; Static Electricity; Substrate Specificity	2008
Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis. RNA (New York, N.Y.), 2010, Volume: 16, Issue:3 Topics: Aptamers, Nucleotide; Bacteria; Flavin Mononucleotide; Lysine; Magnesium; Nucleic Acid Conformation; Regulatory Sequences, Ribonucleic Acid; RNA, Messenger; S-Adenosylmethionine; Scattering, Small Angle; X-Ray Diffraction	2010
Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase. Proceedings of the National Academy of Sciences of the United States of America, 2010, Dec-07, Volume: 107, Issue:49 Topics: Animals; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cystathionine beta-Synthase; Drosophila Proteins; Lysine; Protein Structure, Tertiary; S-Adenosylmethionine; Static Electricity	2010
An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. PloS one, 2010, Nov-23, Volume: 5, Issue:11 Topics: Binding Sites; DNA-Binding Proteins; HeLa Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunoprecipitation; Lysine; Methylation; Methyltransferases; Models, Biological; Mutation; Myeloid-Lymphoid Leukemia Protein; Nuclear Proteins; Protein Binding; Protein Multimerization; RNA Interference; S-Adenosylmethionine; Substrate Specificity; Transcription Factors	2010
A chemical method for labeling lysine methyltransferase substrates. Chembiochem : a European journal of chemical biology, 2011, Jan-24, Volume: 12, Issue:2 Topics: Alkynes; Epigenomics; Lysine; Methyltransferases; Molecular Structure; Recombinant Proteins; S-Adenosylmethionine; Staining and Labeling; Substrate Specificity	2011
Modeling a new water channel that allows SET9 to dimethylate p53. PloS one, 2011, Volume: 6, Issue:5 Topics: Catalysis; Crystallography, X-Ray; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Models, Molecular; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Tumor Suppressor Protein p53; Water	2011
Methylation of nuclear proteins of Novikoff hepatoma. Carcinogenesis, 1980, Volume: 1, Issue:2 Topics: Animals; Cell Nucleus; Histones; Kinetics; Liver; Liver Neoplasms, Experimental; Lysine; Male; Methylation; Nuclear Proteins; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine	1980
Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells. Experimental and molecular pathology, 2012, Volume: 92, Issue:3 Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Nucleus; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Hepatitis, Alcoholic; Hepatocytes; Histones; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Lysine; Mallory Bodies; Methylation; Mice; Microscopy, Electron; Polycomb Repressive Complex 2; Proliferating Cell Nuclear Antigen; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Transcription Factors	2012
Catalytic and functional roles of conserved amino acids in the SET domain of the S. cerevisiae lysine methyltransferase Set1. PloS one, 2013, Volume: 8, Issue:3 Topics: Amino Acid Sequence; Amino Acid Substitution; Catalytic Domain; Cell Cycle Proteins; Conserved Sequence; DNA, Ribosomal; Gene Expression Regulation, Fungal; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Kinetochores; Lysine; Microtubule-Associated Proteins; Molecular Sequence Data; Mutation; RNA, Small Interfering; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Substrate Specificity	2013
Automethylation of protein arginine methyltransferase 8 (PRMT8) regulates activity by impeding S-adenosylmethionine sensitivity. The Journal of biological chemistry, 2013, Sep-27, Volume: 288, Issue:39 Topics: Catalysis; HeLa Cells; Humans; Lysine; Membrane Proteins; Methylation; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine	2013
Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity. The Journal of biological chemistry, 2015, Jan-02, Volume: 290, Issue:1 Topics: Acyl-CoA Dehydrogenases; Amino Acid Sequence; Electron-Transferring Flavoproteins; Escherichia coli; Gene Expression; Glutaryl-CoA Dehydrogenase; HEK293 Cells; HeLa Cells; Humans; Lysine; Methylation; Methyltransferases; Mitochondria; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; S-Adenosylmethionine; Sequence Alignment	2015
A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A. Biochemical and biophysical research communications, 2014, Dec-12, Volume: 455, Issue:3-4 Topics: Amino Acid Motifs; Amino Acid Sequence; Computational Biology; Evolution, Molecular; Gene Deletion; Genotype; Histone-Lysine N-Methyltransferase; Lysine; Mass Spectrometry; Peptide Elongation Factor 1; Protein Processing, Post-Translational; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2014
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Nature cell biology, 2015, Volume: 17, Issue:12 Topics: Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Epigenesis, Genetic; Gas Chromatography-Mass Spectrometry; Gene Expression Profiling; Gene Knockdown Techniques; Histones; Human Embryonic Stem Cells; Humans; Lysine; Mass Spectrometry; Metabolome; Metabolomics; Methylation; Mice; Niacinamide; Nicotinamide N-Methyltransferase; Proteomics; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Signal Transduction	2015
Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase. The Journal of biological chemistry, 2016, Feb-12, Volume: 291, Issue:7 Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Computational Biology; Enzyme Stability; Isoenzymes; Lysine; Methylation; Models, Molecular; Mutation; Peptide Elongation Factor Tu; Protein Conformation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein Unfolding; Pseudomonas aeruginosa; Recombinant Fusion Proteins; S-Adenosylmethionine; Sequence Homology, Amino Acid; Substrate Specificity; Temperature	2016
S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3. Proceedings of the National Academy of Sciences of the United States of America, 2016, May-31, Volume: 113, Issue:22 Topics: Crystallography, X-Ray; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methionine; Mutation; Peptide Fragments; S-Adenosylmethionine; Substrate Specificity	2016
MTHFD1 controls DNA methylation in Arabidopsis. Nature communications, 2016, 06-13, Volume: 7 Topics: Arabidopsis; Arabidopsis Proteins; Cytoplasm; DNA Demethylation; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Expression Regulation, Plant; Gene Silencing; Green Fluorescent Proteins; Histones; Homeostasis; Lysine; Methenyltetrahydrofolate Cyclohydrolase; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Models, Biological; Mutation; Protein Transport; S-Adenosylmethionine; Tetrahydrofolates	2016
aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism. Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:9 Topics: Archaeal Proteins; Crystallography, X-Ray; Gene Deletion; Gene Expression Regulation, Archaeal; Lysine; Mass Spectrometry; Methylation; Models, Molecular; Protein Methyltransferases; Protein Structure, Secondary; Proteomics; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfolobus	2016
Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8. Proceedings of the National Academy of Sciences of the United States of America, 2016, 12-27, Volume: 113, Issue:52 Topics: Binding, Competitive; Catalysis; Cell Cycle; Computer Simulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Isotopes; Kinetics; Lysine; Methylation; Models, Molecular; Models, Theoretical; Neoplasm Metastasis; Peptides; Protein Structure, Secondary; S-Adenosylmethionine; Software; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity	2016
Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci. ACS chemical biology, 2017, 04-21, Volume: 12, Issue:4 Topics: Amino Acid Sequence; Electron Spin Resonance Spectroscopy; Enzymes; Lysine; Peptides; S-Adenosylmethionine; Sequence Homology, Amino Acid; Spectrophotometry, Ultraviolet; Streptococcus agalactiae; Streptococcus suis; Tryptophan	2017
A Metabolic Function for Phospholipid and Histone Methylation. Molecular cell, 2017, Apr-20, Volume: 66, Issue:2 Topics: Cysteine; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Histones; Lysine; Methylation; Mutation; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Protein Phosphatase 2; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Transcription, Genetic	2017
Polycomb repressive complex 2 in an autoinhibited state. The Journal of biological chemistry, 2017, 08-11, Volume: 292, Issue:32 Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Apoenzymes; Chaetomium; Coenzymes; Conserved Sequence; Enhancer of Zeste Homolog 2 Protein; Fungal Proteins; Histones; Lysine; Methylation; Models, Molecular; Mutation; Peptide Fragments; Polycomb Repressive Complex 2; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Recombinant Fusion Proteins; S-Adenosylmethionine; Xenopus laevis; Xenopus Proteins	2017
Computational characterization of substrate and product specificities, and functionality of S-adenosylmethionine binding pocket in histone lysine methyltransferases from Arabidopsis, rice and maize. Proteins, 2018, Volume: 86, Issue:1 Topics: Arabidopsis; Binding Sites; Catalysis; Databases, Protein; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Models, Chemical; Molecular Structure; Oryza; Plant Proteins; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; S-Adenosylmethionine; Sequence Analysis, Protein; Substrate Specificity; Zea mays	2018
Lysine Possesses the Optimal Chain Length for Histone Lysine Methyltransferase Catalysis. Scientific reports, 2017, 11-23, Volume: 7, Issue:1 Topics: Catalysis; Histone-Lysine N-Methyltransferase; Humans; Lysine; Magnetic Resonance Spectroscopy; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2017
Oligomerization and Auto-methylation of the Human Lysine Methyltransferase SETD6. Journal of molecular biology, 2018, 10-19, Volume: 430, Issue:21 Topics: Gene Expression Regulation, Enzymologic; HEK293 Cells; Humans; Lysine; Methylation; Models, Molecular; Molecular Weight; Oxidative Stress; Point Mutation; Protein Conformation; Protein Methyltransferases; Protein Multimerization; S-Adenosylmethionine	2018
Substrate-Differentiated Transition States of SET7/9-Catalyzed Lysine Methylation. Journal of the American Chemical Society, 2019, 05-22, Volume: 141, Issue:20 Topics: Catalysis; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; S-Adenosylmethionine; Tumor Suppressor Protein p53	2019
Identification of a radical SAM enzyme involved in the synthesis of archaeosine. Nature chemical biology, 2019, Volume: 15, Issue:12 Topics: Databases, Genetic; Enzymes; Gene Expression Profiling; Guanosine; Lysine; S-Adenosylmethionine; Substrate Specificity	2019
Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB. Proceedings of the National Academy of Sciences of the United States of America, 2021, 05-25, Volume: 118, Issue:21 Topics: Bacterial Proteins; Binding Sites; Catalysis; Cloning, Molecular; Electron Spin Resonance Spectroscopy; Escherichia coli; Gene Expression; Genetic Vectors; Iron-Sulfur Proteins; Kinetics; Lysine; Models, Molecular; Oxidation-Reduction; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Ribosomal Proteins; S-Adenosylmethionine; Streptococcus; Substrate Specificity; Thermodynamics; Tryptophan	2021
Flagellin lysine methyltransferase FliB catalyzes a [4Fe-4S] mediated methyl transfer reaction. PLoS pathogens, 2021, Volume: 17, Issue:11 Topics: Bacterial Proteins; Flagellin; Iron-Sulfur Proteins; Lysine; Methylation; Methyltransferases; S-Adenosylmethionine; Salmonella typhi	2021
The Biochemical Landscape of Riboswitch Ligands. Biochemistry, 2022, 02-01, Volume: 61, Issue:3 Topics: Aptamers, Nucleotide; Binding Sites; Glutamine; Glycine; Ligands; Lysine; Riboswitch; RNA, Bacterial; S-Adenosylmethionine	2022
Black carrot extract protects against hepatic injury through epigenetic modifications. Journal of food biochemistry, 2022, Volume: 46, Issue:10 Topics: Adenosine Monophosphate; Animals; Butanols; Cyclic Nucleotide Phosphodiesterases, Type 4; Daucus carota; Epigenesis, Genetic; Ethanol; Histones; Lysine; Methionine Adenosyltransferase; Plant Extracts; Rats; RNA, Messenger; S-Adenosylmethionine; Sirtuin 1	2022
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2. Journal of medicinal chemistry, 2023, 06-08, Volume: 66, Issue:11 Topics: Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Lysine; Polycomb Repressive Complex 2; S-Adenosylmethionine	2023
The FAM86 domain of FAM86A confers substrate specificity to promote EEF2-Lys525 methylation. The Journal of biological chemistry, 2023, Volume: 299, Issue:7 Topics: Crystallography, X-Ray; Humans; Lysine; Methylation; Methyltransferases; Models, Molecular; Peptide Elongation Factor 2; Point Mutation; Protein Domains; Protein Structure, Tertiary; S-Adenosylmethionine; Substrate Specificity	2023