Compounds > lysine
Page last updated: 2024-08-17

lysine and s-adenosylhomocysteine

lysine has been researched along with s-adenosylhomocysteine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's2 (10.00)18.2507
2000's9 (45.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
DiMaria, P; Kim, S; Paik, WK1
Ault-Riché, DB; Borchardt, RT; Yuan, CS1
Beinert, H; Booker, S; Frey, PA; Lieder, KW; Reed, GH; Ruzicka, FJ1
Borchardt, RT; Robins, MJ; Wnuk, SF; Yang, X; Yin, D1
Cheng, X; Horton, JR; Khan, SI; Selker, EU; Tamaru, H; Yang, Z; Zhang, X1
Barlev, NA; Chuikov, S; Gamblin, SJ; Ivanov, GS; Justin, N; Kurash, JK; McKinney, K; Prives, C; Reinberg, D; Tempst, P; Wilson, JR; Xiao, B1
Chin, HG; Estève, PO; Jacobsen, SE; Patnaik, D; Pradhan, S1
Farooq, A; Manzur, K; Qian, C; Wang, R; Wang, X; Zeng, L; Zhou, MM1
Couture, JF; Dietzel, K; Dirk, LM; Flynn, EM; Houtz, RL; Trievel, RC1
Bruice, TC; Zhang, X2
Brehm, A; Imhof, A; Kremmer, E; Meier, K; Scharf, AN; Seitz, V1
Ding, J; Sun, B; Wu, J; Xu, S; Zhong, C1
Bai, Q; Du, Y; Hai, J; Hu, T; Jin, N; Shen, Y; Wang, F; Wang, Q; Yang, J; Yao, X1
Ding, J; Xu, S; Zhang, T; Zhong, C1
Li, J; Wei, H; Zhou, MM1
Chen, Y; Chu, Y; Deng, H; Huang, L; Li, W; Liu, D; Liu, ZJ; Ma, J; Ouyang, S; Wang, T; Zhang, Z; Zhu, Y1
Kuang, Z; Sutter, BM; Tu, BP; Wang, Y; Ye, C1
Kang, J; Kim, J; Lee, S1
Alkafri, N; Bissardon, C; Bohic, S; Charlet, L; Conlan, RS; Francis, LW; Gazze, S; Gonzalez, D; Gourlan, AT; James, DW; Knodel, F; Proux, O; Quintela, M; Rathert, P; Toubhans, B1

Other Studies

20 other study(ies) available for lysine and s-adenosylhomocysteine

ArticleYear
Cytochrome c specific methylase from wheat germ.
    Biochemistry, 1982, Mar-02, Volume: 21, Issue:5

    Topics: Cytochrome c Group; Histone-Lysine N-Methyltransferase; Lysine; Protein Methyltransferases; S-Adenosylhomocysteine; Triticum

1982
A single mutation at lysine 426 of human placental S-adenosylhomocysteine hydrolase inactivates the enzyme.
    The Journal of biological chemistry, 1994, Dec-16, Volume: 269, Issue:50

    Topics: Adenosylhomocysteinase; Arginine; Base Sequence; Binding Sites; Catalysis; DNA Primers; Humans; Hydrolases; Lysine; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Placenta; Protein Binding; S-Adenosylhomocysteine; Structure-Activity Relationship

1994
S-Adenosylmethionine-dependent reduction of lysine 2,3-aminomutase and observation of the catalytically functional iron-sulfur centers by electron paramagnetic resonance.
    Biochemistry, 1998, Feb-24, Volume: 37, Issue:8

    Topics: Binding Sites; Catalysis; Clostridium; Cobalt; Dithionite; Electron Spin Resonance Spectroscopy; Free Radicals; Intramolecular Transferases; Iron; Lysine; Oxidation-Reduction; Photochemistry; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur

1998
Mechanisms of inactivation of human S-adenosylhomocysteine hydrolase by 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosines.
    Biochemistry, 2000, Dec-12, Volume: 39, Issue:49

    Topics: Adenine; Adenosylhomocysteinase; Chlorides; Deoxyadenosines; Enzyme Inhibitors; Halogens; Humans; Hydrolases; Lysine; Models, Molecular; NAD; Peptide Mapping; S-Adenosylhomocysteine; Spectrometry, Mass, Fast Atom Bombardment

2000
Structural basis for the product specificity of histone lysine methyltransferases.
    Molecular cell, 2003, Volume: 12, Issue:1

    Topics: Catalytic Domain; Cysteine; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Macromolecular Substances; Methyltransferases; Models, Molecular; Molecular Structure; Neurospora crassa; Peptides; Protein Methyltransferases; Protein Structure, Tertiary; S-Adenosylhomocysteine; Sulfur; Zinc

2003
Regulation of p53 activity through lysine methylation.
    Nature, 2004, Nov-18, Volume: 432, Issue:7015

    Topics: Amino Acid Sequence; Apoptosis; Cell Line; Cell Nucleus; Gene Expression Regulation; Genes, p53; Genes, ras; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Promoter Regions, Genetic; Protein Binding; Protein Conformation; Protein Methyltransferases; RNA, Messenger; S-Adenosylhomocysteine; Substrate Specificity; Thermodynamics; Tumor Suppressor Protein p53

2004
Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis.
    Biochemistry, 2006, Mar-14, Volume: 45, Issue:10

    Topics: Amino Acid Sequence; Animals; Baculoviridae; Catalytic Domain; Cell Line; Chromatin; Coenzymes; Dose-Response Relationship, Drug; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Methyltransferases; Models, Biological; Molecular Sequence Data; Peptides; Protein Methyltransferases; Recombinant Proteins; Repressor Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Spodoptera; Substrate Specificity; Time Factors

2006
Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase.
    Journal of molecular biology, 2006, May-26, Volume: 359, Issue:1

    Topics: Amino Acid Sequence; Animals; DNA Mutational Analysis; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Paramecium; Peptides; Phycodnaviridae; Protein Methyltransferases; Protein Structure, Quaternary; S-Adenosylhomocysteine; Sequence Alignment; Viral Proteins

2006
Kinetic manifestation of processivity during multiple methylations catalyzed by SET domain protein methyltransferases.
    Biochemistry, 2007, Mar-27, Volume: 46, Issue:12

    Topics: Adenosine; Animals; Catalysis; Cattle; Cell Cycle Proteins; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Kinetics; Lysine; Methylation; Methyltransferases; Models, Chemical; Multienzyme Complexes; Pisum sativum; Plant Proteins; Protein Methyltransferases; Protein Structure, Tertiary; S-Adenosylhomocysteine; Schizosaccharomyces pombe Proteins

2007
Enzymatic mechanism and product specificity of SET-domain protein lysine methyltransferases.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Apr-15, Volume: 105, Issue:15

    Topics: Chromatin; Histone-Lysine N-Methyltransferase; Lysine; Methylation; Models, Molecular; Quantum Theory; S-Adenosylhomocysteine; S-Adenosylmethionine

2008
Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8.
    Biochemistry, 2008, Jun-24, Volume: 47, Issue:25

    Topics: Catalysis; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Quantum Theory; S-Adenosylhomocysteine; S-Adenosylmethionine; Static Electricity; Substrate Specificity

2008
Monomethylation of lysine 20 on histone H4 facilitates chromatin maturation.
    Molecular and cellular biology, 2009, Volume: 29, Issue:1

    Topics: Acetylation; Animals; Cell Extracts; Chromatin; Chromatin Assembly and Disassembly; Drosophila melanogaster; Drosophila Proteins; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Nucleosomes; Peptides; Protein Binding; S-Adenosylhomocysteine; Substrate Specificity

2009
Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.
    Nucleic acids research, 2011, Volume: 39, Issue:10

    Topics: Binding Sites; Biocatalysis; DNA; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Models, Molecular; Protein Structure, Tertiary; Repetitive Sequences, Amino Acid; S-Adenosylhomocysteine

2011
Modeling a new water channel that allows SET9 to dimethylate p53.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Catalysis; Crystallography, X-Ray; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Models, Molecular; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Tumor Suppressor Protein p53; Water

2011
Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins.
    Journal of molecular cell biology, 2011, Volume: 3, Issue:5

    Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; DNA-Binding Proteins; Histone-Lysine N-Methyltransferase; Histones; Humans; Isoenzymes; Lysine; Models, Molecular; Molecular Sequence Data; Muscle Proteins; Protein Structure, Tertiary; S-Adenosylhomocysteine; Substrate Specificity; Transcription Factors; Tumor Suppressor Protein p53

2011
Structure-guided design of a methyl donor cofactor that controls a viral histone H3 lysine 27 methyltransferase activity.
    Journal of medicinal chemistry, 2011, Nov-10, Volume: 54, Issue:21

    Topics: Chlorella; Coenzymes; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Models, Molecular; Mutation; Paramecium; Protein Conformation; S-Adenosylhomocysteine; Stereoisomerism; Structure-Activity Relationship; Viral Proteins

2011
aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:9

    Topics: Archaeal Proteins; Crystallography, X-Ray; Gene Deletion; Gene Expression Regulation, Archaeal; Lysine; Mass Spectrometry; Methylation; Models, Molecular; Protein Methyltransferases; Protein Structure, Secondary; Proteomics; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfolobus

2016
A Metabolic Function for Phospholipid and Histone Methylation.
    Molecular cell, 2017, Apr-20, Volume: 66, Issue:2

    Topics: Cysteine; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Histones; Lysine; Methylation; Mutation; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Protein Phosphatase 2; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Transcription, Genetic

2017
Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis.
    Scientific reports, 2019, 05-30, Volume: 9, Issue:1

    Topics: Bacterial Proteins; Catalytic Domain; Catechol O-Methyltransferase; Coenzymes; Crystallography, X-Ray; Enzyme Assays; Lysine; Methylation; Models, Molecular; Mutation; Mycobacterium tuberculosis; Recombinant Proteins; S-Adenosylhomocysteine; Strontium; Substrate Specificity

2019
Selenium nanoparticles modulate histone methylation via lysine methyltransferase activity and S-adenosylhomocysteine depletion.
    Redox biology, 2023, Volume: 61

    Topics: Antioxidants; Chitosan; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; S-Adenosylhomocysteine; Selenium

2023