Page last updated: 2024-08-17

lysine and pyridoxal phosphate

lysine has been researched along with pyridoxal phosphate in 412 studies

Research

Studies (412)

TimeframeStudies, this research(%)All Research%
pre-1990209 (50.73)18.7374
1990's125 (30.34)18.2507
2000's44 (10.68)29.6817
2010's22 (5.34)24.3611
2020's12 (2.91)2.80

Authors

AuthorsStudies
Cohen, PP; Marshall, M1
Botes, DP; Viljoen, CC; Visser, L1
Gilbert, HF; O'Leary, MH1
Cosson, MP; Gros, C; Pantaloni, D; Talbot, JC1
Gibbons, I; Ritchey, JM; Schachman, HK1
Martinez-Carrion, M; Slebe, JC1
Tabita, FR; Whitman, WB1
Barker, HA; Bozler, G; Hensley, C; Ohsugi, M; Robertson, JM1
Murphy, AJ1
Degani, Y; Duggleby, RG; Nyc, JF; Smith, EL1
Mukohata, Y; Sugiyama, Y1
Harrison, JH; Wimmer, MJ1
Chen, SS; Engel, PC5
Bevilacqua, R; Boccù, E; Brown, DM; Veronese, FM1
Carne, TJ; Flynn, TG1
Roberts, MF; Switzer, RL1
Blaner, WS; Churchich, J1
Barbeau, A; Ngo, TT1
Rosner, A1
Borisova, SN; Dudkin, SM; Geidarov, TG; Karabachyan, LV; Karpeisky, MY; Shlyapnikov, SV1
Levy, HR; Milhausen, M1
Bull, P; Martial, J; Valenzuela, P; Venegas, A; Zaldivar, J2
Camici, G; Manao, G; Ramponi, G; White, GF1
Kempe, TD; Stark, GR1
Nandi, DL1
Andreone, P; Frerman, FE; Mielke, D1
Grove, TH; Levy, HR1
Reed, TA; Schnackerz, KD1
Aurebekk, B; Little, C1
Chirikjian, JG; Lee, YH1
Borders, CL; George, AL1
Bellini, T; Dallocchio, F; Rippa, M; Signorini, M1
Paech, C; Tolbert, NE1
McCurry, SD; Paech, C; Pierce, J; Tolbert, NE1
Haugen, T; Ishaque, A; Preiss, J1
Misono, H; Soda, K2
Marie, AL1
Bacharach, AD; Markland, FS; O'Grady, TC; Saunders, GC; Umemura, N; Weber, BH1
Brown, WE; Marcus, F; Riquelme, P1
De Marco, C; Dernini, S; Rinaldi, A1
Green, PC; Kemp, RG; Ladror, US; Latshaw, SP1
Holmes, EH1
Dierks, T; Krämer, R; Salentin, A; Stappen, R1
Macek, P; Turk, T1
Nakagawa, H; Ogura, N; Sato, T; Sato, Y; Shiraishi, N1
Fukui, T; Matsuyama, T; Soda, K; Tanizawa, K1
Bode, R; Hammer, T1
Gomez-Moreno, C; Medina, M; Mendez, E1
Bohney, JP; Feldhoff, RC; Fonda, ML1
Grimm, B; Smith, MA; von Wettstein, D1
Müller, H; Passow, H; Sovak, M; Wood, PG1
Engel, PC; Lilley, KS1
Kim, CH; King, TE1
Basu, A; Basu, S; Modak, MJ2
Ackermann, B; Bey, P; Lu, L; Pegg, AE; Poulin, R1
Kirsch, JF; Toney, MD2
Guillin, MC; Huisse, MG; Jandrot-Perrus, M; Ternisien, C1
Fukui, T; Kazuta, Y; Tanizawa, K1
Hirose, K; Kawata, Y; Tokushige, M; Yumoto, N1
Greenaway, FT; Ledbetter, JW; Redmond, RW1
Gnatenko, DV; Korneliuk, AI; Lavrik, OI1
Schinzel, R1
Bickel-Sandkötter, S; Horbach, M; Meyer, HE1
Churchich, JE; Kim, YT1
Misono, H; Soda, K; Tanizawa, K; Yagi, T; Yoshimura, T1
Cross, RL; LaDine, JR1
Esaki, N; Futaki, S; Manning, JM; Nishimura, K; Soda, K; Tanizawa, K; Yoshimura, T1
Dwyer, BP2
Salhany, JM1
Fukui, T; Kazuta, Y; Nakano, K; Omura, Y; Tagaya, M1
Guidinger, PF; Nowak, T1
Badet, B; Golinelli-Pimpaneau, B1
Dekker, EE; Mukherjee, JJ1
Christen, P; Gehring, H; Jaussi, R; Ziak, M1
Linder, D; Lumper, L; Müller, K1
Dong, Q; Fromm, HJ1
Cuchillo, CM; Parés, X; Richardson, RM1
Flynn, TG; Hyndman, DJ; Lyons, C1
Futaki, S; Manning, JM; Martinez del Pozo, A; Pospischil, MA; Ringe, D; Soda, K; Stoddard, B; Tanizawa, K; Ueno, H; Yoshimura, T1
Hinz, HR; Kirley, TL1
Gellert, M; Tamura, JK1
Colanduoni, J; Villafranca, JJ1
Basu, A; Gerard, GF; Modak, MJ; Nanduri, VB1
Basu, A; Modak, MJ; Tirumalai, RS1
Ahmed, SA; Kawasaki, H; Miles, EW; Morita, H; Nagata, S1
Phillips, SC1
Basu, A; Kedar, P; Modak, MJ; Wilson, SH1
Church, FC; Kalayanamit, T; Meade, JB; Noyes, CM; Pratt, CW; Sherrill, GB; Tobin, RB1
Abell, C; Alefounder, PR; Battersby, AR; Hart, GJ; Miller, AD; Packman, LC1
Almo, SC; Ringe, D; Smith, DL; Toney, MD1
Futai, M; Maeda, M; Tagaya, M; Tamura, S1
Komatsu-Takaki, M2
Sárközi, E; Szilágyi, L1
Nagamatsu, A; Ohki, H; Shimeno, H; Soeda, S1
Cho, YK; Cook, PF1
Cross, RL; Cunningham, D; Rao, R; Senior, AE1
Bauer, SC; Bild, GS; Borgmeyer, JR; Huynh, QK; Kishore, GM1
Kitajima, S; Thomas, H; Uyeda, K1
Axelrod, H; Greene, SM; McPherson, A1
Aquila, H; Bogner, W; Klingenberg, M1
Fukui, T; Tagaya, M; Yagami, T1
Avaeva, SM; Komissarov, AA; Shpanchenko, OV; Skliankina, VA1
Avaeva, SM; Komissarov, AA; Skliankina, VA1
Andreo, CS; Iglesias, AA; Podesta, FE1
Müller, RE; Traish, AM1
Dominici, P; Tancini, B; Voltattorni, CB1
Balasubramanian, KA; Baskaran, S1
Blackburn, MN; Church, FC; Noyes, CM; Pecon, JM; Peterson, CB1
Inoue, Y; Kagamiyama, H; Kuramitsu, S; Morino, Y; Tanase, S1
Choi, SY; Churchich, JE; Kwok, F; Zaiden, E1
Neujahr, HY; Sejlitz, T1
Camardella, L; Caruso, C; Descalzi-Cancedda, F; Di Prisco, G; Romano, M; Rutigliano, B1
Cross, RL; LaDine, JR; Tamura, JK1
Mahrenholz, AM; Roach, PJ; Wang, YH1
Dobryszycki, P; Kochman, M1
Bhatnagar, D; Puri, RN; Roskoski, R1
Cross, RL; Dombroski, AJ; LaDine, JR; Platt, T1
Blumenthal, KM; Smith, EL1
Fischer, EH; Sabo, DL1
Inamasu, M; Yasunobu, KT1
Ernest, MJ; Kim, KH1
Mansour, TE; Setlow, B1
Enser, M; Horecker, BL; Krulwich, TA1
Frieden, C; Goldin, BR1
Colombo, G; Hubert, E; Marcus, F1
McKinley-McKee, JS; Morris, DL1
Hucho, F; Markau, U; Sund, H1
Holbrook, JJ; Wallis, RB1
Colombo, G; Marcus, F1
Degani, Y; Nyc, JF; Smith, EL; Veronese, FM1
Miyake, Y; Yamano, T1
Henderson, LM; Hiles, RA; Triebwasser, KC1
Geroch, ME; Levy, HR; Olive, C1
Piszkiewicz, D; Smith, EL1
Pierpoint, WS1
Finlay, TH1
Hayes, ML; Hyatt, AT1
Hayaishi, O; Inoue, K; Kurosawa, A; Shizuta, Y; Tanabe, T1
Greenwell, P; Jewett, SL; Stark, GR1
Scrutton, MC; White, MD1
Borisova, SN; Matrosov, VI; Shlyapnikov, SV1
Fales, HM; Gin, JB; Miles, EW1
Avramovic-Zikic, O; Shechosky, S; Sodek, J; Welinder, K1
Dharmgrongartama, ED; Finlay, TH; Perlmann, GE1
Goettlich-Riemann, W; Rucker, RB; Tom, K1
Anai, M; Horecker, BL; Lai, CY1
Stevenson, KJ; Stewart, GR1
Churchich, JE; O, KJ1
Goldberg, ME; Raibaud, O1
Harada, M; Nagatsu, T; Nakano, G1
Burridge, N; Churchich, JE1
Jörnvall, H; Rasched, I; Sund, H1
Blethen, SL; Boeker, EA; Snell, EE1
Kumagai, H; Matsui, H; Ogata, K; Ohkishi, H; Yamada, H1
Huberman, A; Tao, M1
Bukhari, AI; Taylor, AL1
Boeker, EA; Fischer, EH; Snell, EE1
Crawford, IP; Fluri, R; Jackson, LE; Lee, WE1
Hill, JM; Mann, PJ1
Grandgenett, DP; Stahly, DP1
Agundis, C; Calderón, J; Córdoba, F; Rivera, P1
Inoue, H; Kasper, CB; Pitot, HC1
Honikel, KO; Madsen, NB1
Morley, CD; Stadtman, TC1
Auld, DS; Raetz, CR1
Morino, Y; Okamoto, M1
Piszkiewicz, D; Smith, EL; Veronese, FM1
Avramovic-Zikic, O; Madsen, NB1
Peraino, C1
Ferri, G; Forcina, BG; Ronchi, S; Zapponi, MC1
Churchich, JE; Irwin, R2
Feeney, RE; Means, GE1
Anderson, JA; Chang, HW; Grandjean, CJ1
Fischer, EH; Forrey, AW; Saari, JC; Sevilla, CL1
Bromwell, K; Guroff, G; Kuzuya, H1
Noltmann, EA; Schnackerz, KD1
Goldstone, AD; Needleman, SB1
Nagatsu, T; Nakano, G1
Okuyama, T; Suzuki, T1
Matsuda, M; Ogur, M1
Childress, CC; Sacktor, B1
Barker, HA; Chirpich, TP; Costilow, RN; Zappia, V1
Deal, WC; Johnson, GS1
Landon, M; Piszkiewicz, D; Smith, EL1
Morley, CG; Stadtman, TC1
Cortijo, M; Shaltiel, S1
O'Dell, BL; Rucker, RB1
Fischer, EH; Forrey, AW; Nolan, C; Olsgaard, RB1
Ogata, K; Yorifuji, T1
Enser, M; Horecker, BL; Pugh, E; Shapiro, S1
Benditt, EP; Kirkwood, CR; Page, RC1
Benditt, EP; Page, RC1
Kamogawa, A1
Osumi, T; Soda, K1
Pontremoli, S; Rippa, M1
Ferri, G; Ronchi, S; Zapponi, MC1
Barker, HA; Costilow, RN; Rochovansky, OM1
Finseth, F; Sizer, IW1
Gaĭko, TP; Solodunov, AA; Stepuro, II1
Bazaes, S; Beytía, E; Eyzaguirre, J; Gómez, I; Jabalquinto, AM; Solís de Ovando, F1
Datsiĩ, II; Gorshkova, II; Lavrik, OI; Nevinskiĩ, GA1
Datta, AG; Horecker, BL; Pontremoli, S; Singh, VN; Suda, H; Xu, GJ1
Goss, NH; Phillips, NF; Wood, HG1
Berrocal, F; Carreras, J1
Arányi, P; Bauer, PT; Büki, KG; Csonka, E; Horváth, I; Machovich, R1
Cook, PF; Kiick, DM1
Bhagwat, AS; McFadden, BA1
Daĭnichenko, VV; Egorov, AM; Popov, VO; Tishkov, VI1
Shoukry, S; Stoops, JK; Wakil, SJ1
Eby, D; Kirtley, ME1
Blackburn, MN; Pecon, JM1
Hamamoto, I; Ichikawa, Y1
Deshmukh, DR; Srivastava, SK1
Iriarte, A; Martinez-Carrion, M; Mattingly, J1
Detera-Wadleigh, S; Hazra, AK; Wilson, SH1
Battersby, AR; Hart, GJ; Leeper, FJ1
Church, FC; Griffith, MJ1
Cross, RL; Koga, PG1
Gregory, JF1
Krüse, J; Verduin, BJ; Visser, AJ1
Kurihara, N; Misono, H; Soda, K; Yagi, T; Yamamoto, T1
Fujioka, M; Ogawa, H1
Kolattukudy, PE; Poulose, AJ1
Kolattukudy, PE; Poulose, AJ; Rogers, L1
Gracy, RW; Lu, HS; Talent, JM1
Cohn, M; Lerman, CL1
Kjellén, KG; Neujahr, HY1
Griffith, MJ; Lundblad, RL; White, GC1
Engel, PC; Gould, KG2
Bürger, E; Görisch, H1
Fukui, S; Kuno, S; Toraya, T1
Little, C; Myrnes, BJ1
Asada, Y; Misono, H; Sawada, S; Soda, K; Suzuki, T; Tanizawa, K1
Camardella, L; Descalzi-Cancedda, F; di Prisco, G; Romano, M1
Fukui, T; Nakano, K; Shimomura, S; Tagaya, M1
Churchich, JE; Kim, DS1
Katiyar, SS; Porter, JW1
Balestrieri, C; Giovane, A; Gualerzi, C1
Flynn, TG; Haghighi, B; Levy, HR1
Stoffel, W; Weimbs, T1
Goyal, A; Katiyar, SS2
Cook, PF; Jacobson, TM; Nalabolu, SR; Simmons, JW; Tai, CH1
Gloss, LM; Kirsch, JF1
Anderberg, SJ1
Gomi, T; Itagaki, E; Mizuguchi, M; Suzuki, K1
Ballinger, MD; Frey, PA; LoBrutto, R; Reed, GH1
Terada, T1
Barber, MJ; Ferreira, GC; Hafez, O; Hunter, GA; Vajapey, U1
Katiyar, SS; Pandey, A1
Hoshino, F; Makino, S; Moriyama, R; Tomida, M1
Furfine, ES; Furman, PA; Hopkins, SE; Martin, JL; Wilson, JE1
Huang, DY; Ichikawa, Y1
Grishin, NV; Kinch, LN; Osterman, AL; Phillips, MA1
Ichikawa, Y; Wu, RF1
Bautista, JM; Luzzatto, L; Mason, PJ1
Christen, P; Gehring, H; Jäger, J; Jansonius, JN; Malashkevich, VN; Sauder, U; Ziak, M1
Bazaes, S; Cardemil, E; Goldie, H; Jabalquinto, AM1
Higaki, T; Kogo, K; Metzler, CM; Metzler, DE; Mollova, ET; Morino, Y; Scott, RD; Tanase, S1
Bickel-Sandkötter, S; Wessels, T1
Fukui, T; Hagiwara, K; Kaya, S; Taniguchi, K; Tsuda, T1
Bazaes, S; Cardemil, E; Goldie, H; Jabalquinto, AM; Silva, R1
Ewalt, KL1
Esaki, N; Kagamiyama, H; Kim, DW; Kuramitsu, S; Matsushima, Y; Soda, K; Yoshimura, T1
Esaki, N; Kim, DW; Satoh, E; Soda, K; Yoshimura, T1
Fukui, T; Katsube, T; Kazuta, Y; Tagaya, M; Tanizawa, K1
Dailey, HA; Ferreira, GC; Neame, PJ1
Kurosawa, M; Murakoshi, I; Saito, K1
Bessman, MJ; Brush, GS1
Bellini, T; Dallocchio, F; Tomasi, M1
Atkinson, T; Gore, MG; Paine, LJ; Perry, N; Popplewell, AG1
Fukui, T; Konishi, Y; Muroya, S; Tanizawa, K1
Daiho, T; Kanazawa, T; Yamagata, K1
Christen, P; Gehring, H; Jäger, J; Jansonius, JN; Jaussi, R; Malashkevich, VN; Ziak, M1
Lu, Z; McPhie, P; Miles, EW; Nagata, S1
Kahana, C; Tobias, KE1
Ferramola de Sancovich, AM; Sancovich, HA; Sopena de Kracoff, YE1
Buell, G; Collo, G; Lewis, C; North, RA; Surprenant, A1
Charng, YY; Preiss, J; Sheng, J1
Carrea, G; D'Arrigo, P; Secundo, F; Servi, S1
Bellocco, E; Cuzzocrea, G; De Gregorio, A; Di Salvo, C; Grimm, R; Iadarola, P; Valentini, G1
Atanasov, B; Kossekova, G; Miteva, M1
Honke, K; Kamio, K; Makita, A1
Ichiyama, A; Ishikawa, K; Kaneko, E1
Katiyar, SS; Sheikh, S1
Cook, PF; Karsten, WE; Kredich, NM; Rege, VD; Schnackerz, KD; Tai, CH1
Chang, LS1
Esaki, N; Hong, SP; Kim, HS; Ro, HS; Seo, HJ; Soda, K; Sung, MH; Yoshimura, T1
Hayakawa, T; Maeno, M; Suzuki, Y; Tsuge, H1
Christen, P; Gramatikova, SI1
Honma, M; Ito, H; Kiuchi, M; Matsui, H; Murakami, T1
Cho, SW; Lee, JE1
Cardemil, E; Chávez, R; Krautwurst, H1
Dairi, T; Kataoka, M; Liu, JQ; Shimizu, S; Yamada, H1
Cho, SW; Choi, SY; Kim, SW; Lee, J; Song, MS1
Iyengar, L; Katiyar, SS; Pandey, A1
Kaya, S; Taniguchi, K; Tsuda, T; Yokoyama, T1
Hayakawa, T; Maeno, M; Morimoto, Y; Suzuki, Y; Tsuge, H1
Hayashi, H; Ikushiro, H; Kagamiyama, H; Kawata, Y1
Kostrzynska, M; Lee, H; Sopher, CR1
Funatsu, H; Hayashi, Y; Kaya, S; Taniguchi, K; Tsuda, T1
Douce, R; Gakière, B; Job, D; Ravanel, S1
Costa, B; Giusti, L; Lucacchini, A; Martini, C1
Katiyar, SS; Mukherjee, S1
Aramaki, E; Kazuta, Y; Kondo, H; Tokunaga, E1
Cardente, EH; Ellenberger, T; Kwon, HJ; Landy, A; Tirumalai, RS1
Hayashi, Y; Kaya, S; Taniguchi, K; Tsuda, T; Yokoyama, T1
Duhaiman, AS; Rabbani, N1
Hayashi, H; Kagamiyama, H; Mizuguchi, H1
Erickson, HK; Kyte, J1
Hao, S; Lu, J; Zhang, H; Zhang, J1
Esaki, N; Kurihara, T; Kurokawa, Y; Soda, K; Watababe, A; Watanabe, A; Yoshimura, T1
Kery, V; Kraus, JP; Manning, MC; Meyer, JD; Poneleit, L1
Morollo, AA; Petsko, GA; Ringe, D1
Sun, S; Toney, MD1
Busto, F; De Arriaga, D; Olano, J; Soler, J1
Ostrovtsova, SA1
Picone, R; Stoughton, DM; Vann, WF; Zapata, G1
Abbott, JJ; Brooks, HB; Jackson, L; Osterman, AL; Phillips, MA1
Harrison, DH; Miziorko, HM; Runquist, JA1
Capobianco, L; Cappello, AR; Daddabbo, L; Miniero, DV; Natuzzi, D; Stipani, I; Stipani, V1
Bartunik, HD; Bourenkow, GP; Clausen, T; Huber, R; Kaiser, JT; Steinbacher, S1
De Cristofaro, R; Landolfi, R1
Ikai, H; Miyoshi, SI; Mutoh, N; Nakao, H; Narimatsu, S; Shinoda, S; Tsuzuki, D; Yamamoto, S1
Davis, WC; Ho, S; Holmes, EH; Macher, BA; Sherwood, AL; Stroud, MR; Upchurch, DA1
Hayashi, H; Hirotsu, K; Kagamiyama, H; Miyahara, I; Mizuguchi, H; Okada, K1
Chen, D; Frey, PA1
Christen, P; Gramatikova, S; Kunz, B; Mouratou, B1
Homma, H; Imai, K; Kamo, N; Lee, JA; Long, Z; Maruyama, T; Nimura, N; Okamoto, T; Oshima, T; Sekine, M; Sumi, M; Yamagishi, A; Yohda, M1
Chen, MH; Ho, CT; Huang, TC1
Beránek, M; Drsata, J; Palicka, V1
Lehman, TD; Ortwerth, BJ1
Ahn, JY; Cho, SW; Lee, EY; Lee, J; Yoon, HY1
Ghosh, S; Mukherjee, K; Ray, M; Ray, S1
Bazzi, MD; Duhaiman, AS; Rabbani, N1
Hall, JA; Maloney, PC1
Bossa, F; De Biase, D; John, RA; Tramonti, A1
Bertoldi, M; Borri Voltattorni, C; Cellini, B; D'Aguanno, S1
HARRINGTON, H; SAKAMI, W1
Banerjee, R; Evande, R; Ojha, S1
Akella, R; Baldwin, J; Goldsmith, EJ; Jackson, LK; Phillips, MA1
Christmann-Franck, S; Der Garabedian, PA; Fermandjian, S; Karabashyan, LV; Mirambeau, G; Vermeersch, JJ1
Chen, HY; Lima, S; Phillips, RS; Shim, D; Sundararaju, B; Tavakoli, K1
Bittner, F; Heidenreich, T; Mendel, RR; Wollers, S1
Craigie, R; Hess, S; Karki, RG; Kotrikadze, N; Kvaratskhelia, M; Le Grice, SF; Nicklaus, MC; Pathak, VK; Shkriabai, N; Williams, KL; Zhang, Y1
Chang, LS; Cheng, YC; Chu, YP; Liou, JC; Yang, CC1
Ahn, JY; An, JJ; Cho, SW; Choi, SY; Eum, WS; Kang, TC; Kim, DW; Kwon, OS; Lee, BR; Lee, KS; Lee, SH; Lee, SR; Park, J; Won, MH; Yoon, CS1
An, JJ; Cho, SW; Choi, HS; Choi, SH; Choi, SY; Eum, WS; Hong, JW; Kim, DW; Kim, SY; Kwon, HY; Kwon, OS; Lee, BR; Lee, KS; Lee, SH; Lee, SR; Park, J1
Ide, N; Kitabatake, N; Masuda, T1
Edgar, AJ1
Creuzenet, C; Obhi, RK1
Appaji Rao, N; Bhavani, S; Jala, VR; Kaul, P; Prakash, V; Savithri, HS; Subramanya, HS; Trivedi, V1
Dubnovitsky, AP; Papageorgiou, AC; Popov, AN; Ravelli, RB1
Carlisle-Moore, L; Gordon, CR; Machutta, CA; Miller, WT; Tonge, PJ1
Giangregorio, N; Indiveri, C; Palmieri, F; Tonazzi, A1
Ajamian, E; Aubry, A; Bhatia, S; Brisson, JR; Cygler, M; Julien, JP; Li, Y; Logan, SM; Lunin, VV; Matte, A; Schoenhofen, IC; Wakarchuk, WW; Young, NM1
Cherney, MM; Clay, MD; Deyholos, MK; Flegel, MD; James, MN; Marcus, SL; van Belkum, MJ; Vederas, JC; Watanabe, N1
Sivakami, S; Suji, G1
Capitani, G; Christen, P; Giannattasio, S; Marra, E; Vacca, RA1
Cherney, MM; Clay, MD; James, MN; van Belkum, MJ; Vederas, JC; Watanabe, N1
Brownlee, JM; Harrison, DH; Kaplan, RS; Kotaria, R; Mayor, JA; Remani, S; Sun, J; Walters, DE1
Maeda, T; Murakami, T; Wada, M; Yokota, A1
Arakawa, N; Eggeling, L; Freudl, R; Lausberg, F; Matsui, D; Oikawa, T; Osumi, S; Stäbler, N1
Chen, HJ; Ko, TP; Lee, CY; Wang, AH; Wang, NC1
Bertoldi, M; Voltattorni, CB1
Chen, HT; Chen, YC; Chen, YL; Hsien, KC; Kao, CL; Lu, CY1
Maeda, T; Murakami, T; Takeda, Y; Wada, M; Yokota, A1
Chan-Huot, M; Limbach, HH; Sharif, S; Tolstoy, PM; Toney, MD1
Loh, CT; Otting, G; Qi, R; Su, XC1
Chan-Huot, M; Denisov, GS; Limbach, HH; Sharif, S; Shenderovich, IG; Tolstoy, PM; Toney, MD1
Amanlou, M; Azizian, H; Habibi-Rezaei, M; Moosavi-Movahedi, AA; Safari, M; Sharifizadeh, A; Torabizadeh, H1
Li, B; Sun, H; Wang, C; Zhu, R1
Albeck, S; Dym, O; Edelman, M; Galili, G; Kirma, M; Sobolev, V; Unger, T1
Brunzelle, JS; Bulfer, SL; Trievel, RC1
Asano, Y; Isobe, K; Matsui, D; Sugawara, A; Takahashi, N; Yamada, M1
Fisher, K; Leys, D; Menon, BR; Rigby, SE; Scrutton, NS1
Brown, WC; Harms, E; Smith, AM; Smith, JL1
Bhatia, SK; Choi, KY; Kim, HJ; Kim, YH; Park, K; Sathiyanarayanan, G; Seo, HM; Shin, JH; Yang, YH1
Arruda, P; Eberlin, MN; Laranjeira, ÂB; MacKenzie, A; Marques, LA; Pena, IA; Yunes, JA1
Amorim Franco, TM; Blanchard, JS; Hegde, S1
García-Villoria, J; Girós, M; Ribes, A; Ruiz, A; Torres, MA; Tort, F; Ugarteburu, O1
Kim, KJ; Sagong, HY1
Bhatia, SK; Choi, YK; Kim, HJ; Kim, J; Kim, JH; Kim, YG; Park, K; Sathiyanarayanan, G; Song, HS; Yang, YH1
Cellini, B; Cutruzzolà, F; Giardina, G; Montioli, R; Paiardini, A; Voltattorni, CB1
Kim, KJ; Son, HF1
Chen, JR; Ke, SC1
Homma, H; Katane, M; Miyamoto, T; Saitoh, Y; Sekine, M1
Berglund, P; Campillo-Brocal, JC; Chen, S; Humble, MS; Logan, DT; Ruggieri, F; Walse, B1
Bouchereau, J; Schiff, M1
Long, M; Ngon, NKA; Osire, T; Rao, Z; Xu, M; Yang, T; Zhang, X1
Bhatia, SK; Cho, JY; Choi, TR; Gurav, R; Han, YH; Kim, HJ; Lee, HS; Lee, SM; Park, K; Park, SL; Song, HS; Yang, YH1
Palmer, DRJ; Prasertanan, T; Sanders, DAR1
Chen, JR; Ke, SC; Li, QY; Maity, AN1
Tsuchida, N; Yamabe, S; Yamazaki, S1
Bias, T; Geldenhuys, WJ; Konkle, ME; Kruger, J; Kunk, C; Mann, A; Markitan, J; Mendoza, G; Menze, MA; Nath, A1
Liu, S; Mi, J; Qi, H; Song, K; Zhang, L1
Al Mughram, MH; Babor, JT; Barile, A; Colotti, G; Contestabile, R; de Crécy-Lagard, V; di Salvo, ML; Donkor, AK; Ghatge, MS; Giorgi, A; Musayev, FN; Paredes, SD; Safo, MK; Tramonti, A1
Nguyen Hoang, KN; Phillips, RS1
Korotkov, SM; Novozhilov, AV1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1

Reviews

6 review(s) available for lysine and pyridoxal phosphate

ArticleYear
Brønsted analysis of enzymatic proton transfer reactions through site-directed mutagenesis.
    Annals of the New York Academy of Sciences, 1990, Volume: 585

    Topics: Animals; Aspartate Aminotransferases; Catalysis; Chemical Phenomena; Chemistry; Kinetics; Lysine; Mutation; Protons; Pyridoxal Phosphate

1990
The role of lysyl, arginyl, and sulfhydryl residues in estrogen receptor activation, 4S to 5S dimerization, and conversion of receptor from a state with low affinity into a state with higher affinity for estrogen.
    Annals of the New York Academy of Sciences, 1986, Volume: 464

    Topics: Alkylation; Animals; Arginine; Cell Nucleus; Cyclohexanones; Dose-Response Relationship, Drug; Hydroxymercuribenzoates; Kinetics; Lysine; Mersalyl; Molecular Weight; Polymers; Protein Conformation; Pyridoxal Phosphate; Receptors, Estrogen; Structure-Activity Relationship; Sulfhydryl Compounds

1986
Exploring the active site in UDP-glucose pyrophosphorylase by affinity labelling and site-directed mutagenesis.
    Biotechnology and applied biochemistry, 1993, Volume: 18, Issue:2

    Topics: Affinity Labels; Amino Acid Sequence; Binding Sites; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Uridine Diphosphate Glucose; UTP-Glucose-1-Phosphate Uridylyltransferase

1993
AMINO ACID METABOLISM.
    Annual review of biochemistry, 1963, Volume: 32

    Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea

1963
Critical hydrogen bonds and protonation states of pyridoxal 5'-phosphate revealed by NMR.
    Biochimica et biophysica acta, 2011, Volume: 1814, Issue:11

    Topics: Amines; Hydrogen Bonding; Lysine; Magnetic Resonance Spectroscopy; Protons; Pyridoxal Phosphate; Solutions; Water

2011
Inherited Disorders of Lysine Metabolism: A Review.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Arginine; Brain; Brain Diseases, Metabolic; Brain Diseases, Metabolic, Inborn; Carnitine; Epilepsy; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Lysine; Metabolic Diseases; Pyridoxal Phosphate; Pyridoxine

2020

Other Studies

406 other study(ies) available for lysine and pyridoxal phosphate

ArticleYear
Kinetics and equilibrium of the inactivation of ornithine transcarbamylases by pyridoxal 5'-phosphate.
    The Journal of biological chemistry, 1977, Jun-25, Volume: 252, Issue:12

    Topics: Aspartate Carbamoyltransferase; Carbamyl Phosphate; Enterococcus faecalis; Hydrogen-Ion Concentration; Kinetics; Liver; Lysine; Ornithine Carbamoyltransferase; Pyridoxal Phosphate; Schiff Bases

1977
Histidine and lysine residues and the activity of phospholipase A2 from the venom of Bitis gabonica.
    Biochimica et biophysica acta, 1977, Jul-08, Volume: 483, Issue:1

    Topics: Acetophenones; Amino Acid Sequence; Amino Acids; Calcium; Circular Dichroism; Histidine; Hydrogen-Ion Concentration; Lysine; Lysophosphatidylcholines; Peptide Fragments; Phospholipases; Pyridoxal Phosphate; Snake Venoms; Structure-Activity Relationship

1977
Reversible modification of amino groups in aspartate aminotransferase.
    Biochimica et biophysica acta, 1977, Jul-08, Volume: 483, Issue:1

    Topics: Amines; Animals; Apoenzymes; Aspartate Aminotransferases; Cytoplasm; Glutarates; Hydrogen-Ion Concentration; Ketones; Kinetics; Lysine; Myocardium; Pentanones; Phosphates; Pyridoxal Phosphate; Pyridoxamine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine

1977
Physicochemical evidence for the existence of two pyridoxal 5'-phosphate binding sites on glutamate dehydrogenase and characterization of their functional role.
    Biochimica et biophysica acta, 1977, Sep-27, Volume: 494, Issue:1

    Topics: Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Guanosine Triphosphate; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Ligands; Liver; Lysine; Molecular Weight; NADP; Protein Conformation; Pyridoxal Phosphate

1977
Reactivation of enzymes by light-stimulated cleavage of reduced pyridoxal 5'-phosphate-enzyme complexes.
    Biochemistry, 1977, Oct-18, Volume: 16, Issue:21

    Topics: Aspartate Carbamoyltransferase; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Serine Dehydratase; Lyases; Lysine; Magnetic Resonance Spectroscopy; Molecular Weight; Photolysis; Protein Binding; Pyridoxal Phosphate; Pyridoxamine; Tryptophanase; Tyrosine; Ultraviolet Rays

1977
Selective chemical modification and 19F NMR in the assignment of a pK value to the active site lysyl residue in aspartate transaminase.
    The Journal of biological chemistry, 1978, Apr-10, Volume: 253, Issue:7

    Topics: Animals; Aspartate Aminotransferases; Binding Sites; Hydrogen-Ion Concentration; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Myocardium; Protein Conformation; Pyridoxal Phosphate; Swine

1978
Modification of Rhodospirillum rubrum ribulose bisphosphate carboxylase with pyridoxal phosphate. 1. Identification of a lysyl residue at the active site.
    Biochemistry, 1978, Apr-04, Volume: 17, Issue:7

    Topics: Bicarbonates; Binding Sites; Carboxy-Lyases; Chlorides; Hexosephosphates; Lysine; Magnesium; NADP; Pentosephosphates; Pyridoxal Phosphate; Rhodospirillum rubrum; Ribulose-Bisphosphate Carboxylase; Schiff Bases

1978
Metabolism of L-beta-lysine in a Pseudomonas: conversion of 6-N-acetyl-L-beta-lysine to 3-keto-6-acetamidohexanoate and of 4-aminobutyrate to succinic semialdehyde by different transaminases.
    Archives of biochemistry and biophysics, 1979, Oct-01, Volume: 197, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Enzyme Induction; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Pseudomonas; Pyridoxal Phosphate; Pyruvates; Substrate Specificity; Transaminases

1979
Sarcoplasmic reticulum adenosine triphosphatase: labeling of an essential lysyl residue with pyridoxal-5'-phosphate.
    Archives of biochemistry and biophysics, 1977, Apr-15, Volume: 180, Issue:1

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Borohydrides; Calcium; Edetic Acid; Kinetics; Lysine; Magnesium; Peptide Fragments; Pyridoxal; Pyridoxal Phosphate; Rabbits; Sarcoplasmic Reticulum

1977
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. V. Tryptic peptides.
    The Journal of biological chemistry, 1977, Nov-25, Volume: 252, Issue:22

    Topics: Amino Acid Sequence; Glutamate Dehydrogenase; Lysine; Neurospora; Neurospora crassa; Peptide Fragments; Pyridoxal Phosphate; Trypsin

1977
Modification of one lysine by pyridoxal phosphate completely inactivates chloroplast coupling factor 1 ATPase.
    FEBS letters, 1979, Feb-15, Volume: 98, Issue:2

    Topics: Chloroplasts; Kinetics; Lysine; Mathematics; Plants; Protein Binding; Proton-Translocating ATPases; Pyridoxal Phosphate

1979
Identification of an essential lysine in porcine heart mitochondrial malate dehydrogenase.
    The Journal of biological chemistry, 1975, Nov-25, Volume: 250, Issue:22

    Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Lysine; Malate Dehydrogenase; Mitochondria, Muscle; Myocardium; NAD; Peptide Fragments; Protein Binding; Pyridoxal Phosphate; Swine; Trypsin

1975
Ox liver glutamate dehydrogenase. The role of lysine-126 reappraised in the light of studies of inhibition and inactivation by pyridoxal 5'-phosphate.
    The Biochemical journal, 1975, Volume: 149, Issue:3

    Topics: Animals; Binding Sites; Binding, Competitive; Cattle; Glutamate Dehydrogenase; Ketoglutaric Acids; Kinetics; Liver; Lysine; NAD; Pyridoxal Phosphate

1975
Horse liver alcohol dehydrogenase. A study of the essential lysine residue.
    The Biochemical journal, 1975, Volume: 149, Issue:3

    Topics: Alcohol Oxidoreductases; Animals; Horses; In Vitro Techniques; Kinetics; Liver; Lysine; Models, Chemical; NAD; Pyridoxal Phosphate; Time Factors

1975
Dogfish M4 lactate dehydrogenase: reversible inactivation by pyridoxal 5'-phosphate and complete protection in complexes that mimic the active ternary complex.
    The Biochemical journal, 1975, Volume: 151, Issue:2

    Topics: Animals; Dogfish; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lysine; NAD; Oxalates; Oxamic Acid; Pyridoxal Phosphate

1975
Purification, characteristics and sequence of a peptide containing an essential lysine residue.
    Biochimica et biophysica acta, 1976, Aug-12, Volume: 445, Issue:1

    Topics: Amino Acids; Animals; Glutamate Dehydrogenase; Kinetics; Liver; Lysine; Molecular Weight; NAD; Peptide Fragments; Pyridoxal Phosphate; Tuna

1976
Studies on phosphoglyceromutase from chicken breast muscle: chemical modification of lysyl residues.
    Canadian journal of biochemistry, 1977, Volume: 55, Issue:8

    Topics: Animals; Binding Sites; Chickens; Circular Dichroism; Kinetics; Lysine; Muscles; Nitrobenzenes; Phosphoglycerate Mutase; Phosphotransferases; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Trinitrobenzenesulfonic Acid

1977
Inactivation of Salmonella phosphoribosylpyrophosphate synthetase by specific chemical modification of a lysine residue.
    Archives of biochemistry and biophysics, 1978, Jan-30, Volume: 185, Issue:2

    Topics: Adenosine Triphosphate; Kinetics; Lysine; Magnesium; Phosphates; Phosphotransferases; Pyridoxal Phosphate; Pyridoxamine; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates; Salmonella typhimurium; Trinitrobenzenesulfonic Acid

1978
Succinic semialdehyde dehydrogenase. Reactivity of lysyl residues.
    The Journal of biological chemistry, 1979, Mar-25, Volume: 254, Issue:6

    Topics: Aldehyde Oxidoreductases; Animals; Brain; Kinetics; Lysine; Molecular Weight; NAD; o-Phthalaldehyde; Pyridoxal Phosphate; Succinates; Swine

1979
Reversible inactivation of rat brain pyruvate dehydrogenase multienzyme complex by pyridoxal 5'-phosphate.
    The International journal of biochemistry, 1979, Volume: 10, Issue:11

    Topics: Animals; Brain; Coenzyme A; Enzyme Reactivators; Kinetics; Lysine; Male; NAD; Pyridoxal Phosphate; Pyruvate Dehydrogenase Complex; Rats

1979
Control of lysine biosynthesis in Bacillus subtilis: inhibition of diaminopimelate decarboxylase by lysine.
    Journal of bacteriology, 1975, Volume: 121, Issue:1

    Topics: Aspartic Acid; Bacillus subtilis; Carbon Radioisotopes; Carboxy-Lyases; Cell-Free System; Chromatography, Gel; Diamines; Hydrogen-Ion Concentration; Isoenzymes; Lysine; Phosphates; Phosphorus Radioisotopes; Phosphotransferases; Pimelic Acids; Pyridoxal Phosphate; Stereoisomerism; Tromethamine

1975
Spectral properties of phosphopyridoxyl-Lys-7(-41)-ribonuclease A.
    Biochimica et biophysica acta, 1975, Mar-28, Volume: 386, Issue:1

    Topics: Binding Sites; Circular Dichroism; Hydrogen-Ion Concentration; Lysine; Protein Binding; Protein Conformation; Protein Denaturation; Pyridoxal Phosphate; Ribonucleases; Spectrophotometry, Ultraviolet; Temperature

1975
Evidence for an essential lysine in glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides.
    European journal of biochemistry, 1975, Jan-02, Volume: 50, Issue:2

    Topics: Binding Sites; Dinitrophenols; Glucosephosphate Dehydrogenase; Kinetics; Leuconostoc; Lysine; Mathematics; NAD; NADP; Protein Binding; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Time Factors

1975
Inactivation of E. coli RNA polymerase by pyridoxal 5'-phosphate: identificationof a low pKa lysine as the modified residue.
    Biochemical and biophysical research communications, 1975, Jun-16, Volume: 64, Issue:4

    Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Borohydrides; DNA-Directed RNA Polymerases; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Time Factors

1975
Inhibition of horse muscle acylphosphatase by pyridoxal 5'-phosphate.
    Biochimica et biophysica acta, 1975, Jun-24, Volume: 391, Issue:2

    Topics: Amino Acids; Animals; Binding Sites; Horses; Hydrogen-Ion Concentration; Kinetics; Lysine; Muscles; Osmolar Concentration; Phosphoric Monoester Hydrolases; Protein Binding; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors

1975
Pyridoxal 5'-phosphate, a fluorescent probe in the active site of aspartate transcarbamylase.
    The Journal of biological chemistry, 1975, Sep-10, Volume: 250, Issue:17

    Topics: Amino Acid Sequence; Amino Acids; Aspartate Carbamoyltransferase; Binding Sites; Hydrogen-Ion Concentration; Lysine; Peptide Fragments; Protein Binding; Pyridoxal Phosphate; Spectrometry, Fluorescence

1975
Delta-aminolevulinic acid synthase of rhodopseudomonas spheroides. Binding of pyridoxal phosphate to the enzyme.
    Archives of biochemistry and biophysics, 1978, Volume: 188, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Apoenzymes; Apoproteins; Borohydrides; Kinetics; Lysine; Oxidation-Reduction; Pyridoxal Phosphate; Rhodobacter sphaeroides; Schiff Bases

1978
Reaction of pyridoxal 5'-phosphate with Escherichia coli CoA transferase: evidence for an essential lysine residue.
    Archives of biochemistry and biophysics, 1977, Volume: 181, Issue:2

    Topics: Acetoacetates; Acetyl-CoA C-Acyltransferase; Acyltransferases; Binding Sites; Coenzyme A; Diacetyl; Escherichia coli; Kinetics; Lysine; Pyridoxal Phosphate

1977
Evidence for an essential lysine residue on the phosphoribosyl transferase subunit of the anthranilate synthetase-anthranilate 5-phosphoribosyl-pyrophosphate phosphoribosyltransferase enzyme complex from Salmonella typhimurium.
    Biochemical and biophysical research communications, 1979, Jan-30, Volume: 86, Issue:2

    Topics: Anthranilate Phosphoribosyltransferase; Anthranilate Synthase; Kinetics; Lysine; Multienzyme Complexes; Pentosyltransferases; Pyridoxal Phosphate; Salmonella typhimurium; Spectrophotometry

1979
The kinetics of Schiff-base formation during reconstitution of D-serine apodehydratase from Escherichia coli with pyridoxal 5'-phosphate.
    European journal of biochemistry, 1979, Feb-15, Volume: 94, Issue:1

    Topics: Apoenzymes; Escherichia coli; Kinetics; L-Serine Dehydratase; Lysine; Mercaptoethanol; Pyridoxal Phosphate; Schiff Bases; Spectrum Analysis; Temperature

1979
Phospholipase C from Bacillus cereus. Evidence for essential lysine residues.
    The Biochemical journal, 1977, Jan-01, Volume: 161, Issue:1

    Topics: Bacillus cereus; Chromatography, Affinity; Imides; Lysine; Phospholipases; Pyridoxal Phosphate; Trinitrobenzenesulfonic Acid

1977
Sequence-specific endonuclease Bgl I. Modification of lysine and arginine residues of the homogeneous enzyme.
    The Journal of biological chemistry, 1979, Aug-10, Volume: 254, Issue:15

    Topics: Arginine; Bacillus; Deoxyribonucleases; Diacetyl; Endonucleases; Kinetics; Lysine; Magnesium; Molecular Weight; Pyridoxal Phosphate

1979
Chemical modification of histidyl and lysyl residues in yeast enolase.
    Biochimica et biophysica acta, 1979, Jul-11, Volume: 569, Issue:1

    Topics: Binding Sites; Diethyl Pyrocarbonate; Enzyme Reactivators; Histidine; Hydroxylamines; Lysine; Osmolar Concentration; Phosphopyruvate Hydratase; Pyridoxal Phosphate; Substrate Specificity; Temperature; Time Factors; Trinitrobenzenesulfonic Acid; Yeasts

1979
The active site of 6-phosphogluconate dehydrogenase. A phosphate binding site and its surroundings.
    Archives of biochemistry and biophysics, 1978, Volume: 189, Issue:2

    Topics: Arginine; Arsenates; Binding Sites; Candida; Diacetyl; Dithionitrobenzoic Acid; Histidine; Lysine; Phosphates; Phosphogluconate Dehydrogenase; Pyridoxal Phosphate; Sulfhydryl Compounds

1978
Active site studies of ribulose-1,5-bisphosphate carboxylase/oxygenase with pyridoxal 5'-phosphate.
    The Journal of biological chemistry, 1978, Nov-10, Volume: 253, Issue:21

    Topics: Binding Sites; Borohydrides; Carboxy-Lyases; Kinetics; Lysine; Oxidation-Reduction; Plants; Pyridoxal Phosphate; Ribulose-Bisphosphate Carboxylase

1978
Active site of ribulose 1,5-bisphosphate carboxylase/oxygenase.
    Basic life sciences, 1978, Volume: 11

    Topics: Arginine; Bicarbonates; Binding Sites; Carboxy-Lyases; Kinetics; Lysine; Magnesium; Pyridoxal Phosphate; Ribulose-Bisphosphate Carboxylase

1978
ADPGlucose pyrophosphorylase: evidence for a lysine residue at the activator site of the Escherichia coli B enzyme.
    Biochemical and biophysical research communications, 1976, Mar-22, Volume: 69, Issue:2

    Topics: Adenosine Diphosphate Glucose; Binding Sites; Borohydrides; Escherichia coli; Fructosephosphates; Hexosediphosphates; Lysine; Nucleotidyltransferases; Organophosphorus Compounds; Protein Binding; Pyridoxal Phosphate

1976
L-Lysine-alpha-ketoglutarate epsilon-aminotransferease. Properties of the bound pyridoxal 5'-phosphate.
    Journal of biochemistry, 1977, Volume: 82, Issue:2

    Topics: Apoenzymes; Circular Dichroism; Flavobacterium; Ketoglutaric Acids; Lysine; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry; Transaminases

1977
Differential effects of pyridoxal 5'-phosphate on lysine residues in rabbit and sturgeon muscle aldolases.
    Canadian journal of biochemistry, 1976, Volume: 54, Issue:8

    Topics: Amino Acids; Animals; Binding Sites; Fishes; Fructose-Bisphosphate Aldolase; Kinetics; Lysine; Muscles; Peptide Fragments; Protein Binding; Pyridoxal Phosphate; Rabbits; Species Specificity

1976
Chemical modification of yeast 3-phosphoglycerate kinase.
    The Journal of biological chemistry, 1975, Feb-25, Volume: 250, Issue:4

    Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Circular Dichroism; Kinetics; Lysine; Maleates; Molecular Weight; Nitro Compounds; Optical Rotatory Dispersion; Peptide Fragments; Phosphoglycerate Kinase; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Trypsin; Tyrosine; Urea

1975
Inactivation of rat liver RNA polymerases I and II and yeast RNA polymerase I by pyrodixal 5'-phosphate. Evidence for the participation of lysyl residues at the active site.
    Biochemistry, 1975, Nov-04, Volume: 14, Issue:22

    Topics: Animals; Binding Sites; Cell Nucleus; DNA-Directed RNA Polymerases; Ethylenediamines; Kinetics; Liver; Lysine; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Rats; Saccharomyces cerevisiae; Spectrophotometry; Spectrophotometry, Ultraviolet

1975
The nature of inhibition and inactivation of bovine liver glutamate dehydrogenase by pyridoxal 5'-phosphate.
    Biochemical Society transactions, 1975, Volume: 3, Issue:1

    Topics: Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Ketoglutaric Acids; Kinetics; Liver; Lysine; Protein Binding; Pyridoxal Phosphate

1975
Modification of bovine pancreatic ribonuclease A with pyridoxal 5'-phosphate. Isolation and identification of derivatives.
    International journal of peptide and protein research, 1975, Volume: 7, Issue:5

    Topics: Amino Acids; Animals; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Lysine; Pancreas; Pyridoxal Phosphate; Ribonucleases

1975
Modification of pig M4 lactate dehydrogenase by pyridoxal 5'-phosphate. Demonstration of an essential lysine residue.
    The Biochemical journal, 1975, Volume: 149, Issue:1

    Topics: Animals; Binding Sites; Borohydrides; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lysine; Muscles; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Swine

1975
Pyridoxal phosphate-catalyzed alpha-beta elimination of selenalysine.
    Archives of biochemistry and biophysics, 1976, Volume: 173, Issue:2

    Topics: Binding Sites; Chemical Phenomena; Chemistry; Kinetics; Lysine; Pyridoxal Phosphate; Selenium; Spectrophotometry; Spectrophotometry, Ultraviolet

1976
Identification of critical lysyl residues in the pyrophosphate-dependent phosphofructo-1-kinase of Propionibacterium freudenreichii.
    Biochemistry, 1992, May-26, Volume: 31, Issue:20

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Diphosphates; Hydrolysis; Lysine; Molecular Sequence Data; Phosphofructokinase-1; Phosphotransferases; Propionibacterium; Pyridoxal Phosphate; Sequence Alignment; Substrate Specificity; Trypsin

1992
Presence of an essential lysine residue in a GDP-fucose protected site of the alpha 1----3fucosyltransferase from human small cell lung carcinoma NCl-H69 cells.
    Archives of biochemistry and biophysics, 1992, Aug-01, Volume: 296, Issue:2

    Topics: Binding Sites; Binding, Competitive; Borohydrides; Carcinoma, Small Cell; Enzyme Activation; Fucosyltransferases; Guanosine Diphosphate Fucose; Humans; Lung Neoplasms; Lysine; Oxidation-Reduction; Pyridoxal Phosphate; Tumor Cells, Cultured

1992
Probing the active site of the reconstituted aspartate/glutamate carrier from bovine heart mitochondria: carbodiimide-catalyzed acylation of a functional lysine residue.
    Biochimica et biophysica acta, 1992, Jan-10, Volume: 1103, Issue:1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acylation; Amino Acid Transport Systems, Acidic; Animals; Antiporters; Aspartic Acid; Binding Sites; Biological Transport; Carrier Proteins; Catalysis; Cattle; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Ethyldimethylaminopropyl Carbodiimide; Glutamates; Glutamic Acid; Kinetics; Lysine; Mitochondria, Heart; Proteolipids; Pyridoxal Phosphate

1992
The role of lysine, histidine and carboxyl residues in biological activity of equinatoxin II, a pore forming polypeptide from the sea anemone Actinia equina L.
    Biochimica et biophysica acta, 1992, Feb-13, Volume: 1119, Issue:1

    Topics: Animals; Cattle; Cnidarian Venoms; Diethyl Pyrocarbonate; Hemolysis; Histidine; Humans; Indicators and Reagents; Isoelectric Focusing; Lipoproteins; Lysine; Molecular Weight; Pyridoxal Phosphate; Sea Anemones; Spectrophotometry

1992
Arginine and lysine residues as NADH-binding sites in NADH-nitrate reductase from spinach.
    Phytochemistry, 1992, Volume: 31, Issue:7

    Topics: Amino Acid Sequence; Arginine; Binding Sites; Diacetyl; Humans; Lysine; Molecular Sequence Data; NAD; NADH, NADPH Oxidoreductases; Nitrate Reductase (NADH); Nitrate Reductases; Phenylglyoxal; Plants; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid

1992
Leucine dehydrogenase from Bacillus stearothermophilus: identification of active-site lysine by modification with pyridoxal phosphate.
    Journal of biochemistry, 1992, Volume: 112, Issue:2

    Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Base Sequence; Binding Sites; Borohydrides; Geobacillus stearothermophilus; Leucine Dehydrogenase; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Pyridoxal Phosphate

1992
Purification and characterization of an inducible L-lysine: 2-oxoglutarate 6-aminotransferase from Candida utilis.
    Journal of basic microbiology, 1992, Volume: 32, Issue:1

    Topics: Candida; Enzyme Induction; Ketoglutaric Acids; Kinetics; L-Lysine 6-Transaminase; Lysine; Pyridoxal Phosphate; Substrate Specificity; Transaminases

1992
Lysine residues on ferredoxin-NADP+ reductase from Anabaena sp. PCC 7119 involved in substrate binding.
    FEBS letters, 1992, Feb-17, Volume: 298, Issue:1

    Topics: Amino Acid Sequence; Anabaena; Binding Sites; Borohydrides; Enzyme Activation; Ferredoxin-NADP Reductase; Lysine; Molecular Sequence Data; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Structure-Activity Relationship; Substrate Specificity

1992
Identification of Lys190 as the primary binding site for pyridoxal 5'-phosphate in human serum albumin.
    FEBS letters, 1992, Feb-24, Volume: 298, Issue:2-3

    Topics: Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; Humans; Lysine; Molecular Sequence Data; Pyridoxal Phosphate; Serum Albumin

1992
The role of Lys272 in the pyridoxal 5-phosphate active site of Synechococcus glutamate-1-semialdehyde aminotransferase.
    European journal of biochemistry, 1992, Jun-01, Volume: 206, Issue:2

    Topics: Base Sequence; Binding Sites; Circular Dichroism; Cyanobacteria; DNA, Bacterial; Intramolecular Transferases; Isomerases; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyridoxal Phosphate

1992
Role of Lys 558 and Lys 869 in substrate and inhibitor binding to the murine band 3 protein: a study of the effects of site-directed mutagenesis of the band 3 protein expressed in the oocytes of Xenopus laevis.
    The Journal of membrane biology, 1992, Volume: 127, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Sequence; Animals; Anion Exchange Protein 1, Erythrocyte; Binding Sites; Biological Transport; Chlorides; Lysine; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Binding; Pyridoxal Phosphate; Stilbenes; Xenopus laevis

1992
The essential active-site lysines of clostridial glutamate dehydrogenase. A study with pyridoxal-5'-phosphate.
    European journal of biochemistry, 1992, Jul-15, Volume: 207, Issue:2

    Topics: Amino Acid Sequence; Binding Sites; Clostridium; Crystallography; Glutamate Dehydrogenase; Kinetics; Lysine; Molecular Sequence Data; Peptide Fragments; Protein Conformation; Pyridoxal Phosphate

1992
Effect of pyridoxal phosphate on the formation of cytochrome c1-c and cytochrome c-cytochrome oxidase complexes.
    Biochemistry international, 1991, Volume: 24, Issue:2

    Topics: Ascorbic Acid; Cytochrome c Group; Cytochromes c1; Dithionite; Electron Transport Complex IV; Hydrogen-Ion Concentration; Lysine; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet

1991
Site-directed mutagenesis of Moloney murine leukemia virus reverse transcriptase. Demonstration of lysine 103 in the nucleotide binding site.
    The Journal of biological chemistry, 1990, Oct-05, Volume: 265, Issue:28

    Topics: Base Sequence; Binding Sites; DNA Replication; DNA-Directed DNA Polymerase; Endoribonucleases; Escherichia coli; Lysine; Molecular Sequence Data; Moloney murine leukemia virus; Mutagenesis, Site-Directed; Oligonucleotide Probes; Plasmids; Pyridoxal Phosphate; Recombinant Proteins; Restriction Mapping; Ribonuclease H; RNA-Directed DNA Polymerase; Templates, Genetic

1990
Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites.
    The Journal of biological chemistry, 1992, Jan-05, Volume: 267, Issue:1

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Chromatography, High Pressure Liquid; Coenzymes; Eflornithine; Escherichia coli; Lysine; Mice; Molecular Sequence Data; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pyridoxal Phosphate; Recombinant Proteins; Spectrometry, Mass, Fast Atom Bombardment; Trypsin

1992
The K258R mutant of aspartate aminotransferase stabilizes the quinonoid intermediate.
    The Journal of biological chemistry, 1991, Dec-15, Volume: 266, Issue:35

    Topics: Amino Acid Sequence; Aspartate Aminotransferases; Keto Acids; Kinetics; Lysine; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Quinones; Schiff Bases; Substrate Specificity

1991
Effect of phosphopyridoxylation on thrombin interaction with platelet glycoprotein Ib.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1991, Volume: 2, Issue:4

    Topics: Binding Sites; Cross-Linking Reagents; Cyanogen Bromide; Heparin; Hirudins; Humans; Lysine; Molecular Weight; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Pyridoxal Phosphate; Thrombin; Tritium; Trypsin

1991
Comparative affinity labeling with reactive UDP-glucose analogues: possible locations of five lysyl residues around the substrate bound to potato tuber UDP-glucose pyrophosphorylase.
    Journal of biochemistry, 1991, Volume: 110, Issue:5

    Topics: Affinity Labels; Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; Enzyme Activation; Kinetics; Lysine; Molecular Sequence Data; Pyridoxal Phosphate; Solanum tuberosum; Substrate Specificity; Uridine Diphosphate Glucose; UTP-Glucose-1-Phosphate Uridylyltransferase

1991
Identification of lysyl residues at the AMP-binding site of biodegradative threonine deaminase from Escherichia coli.
    Journal of biochemistry, 1991, Volume: 110, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Affinity Labels; Allosteric Site; Enzyme Activation; Escherichia coli; Kinetics; Lysine; Pyridoxal Phosphate; Threonine Dehydratase

1991
Hydrated electron formation on laser excitation of P-pyridoxyl amino acids and proteins.
    Photochemistry and photobiology, 1991, Volume: 54, Issue:5

    Topics: Electrons; Free Radicals; Half-Life; Kinetics; Lasers; Lysine; Nitrogen Dioxide; Photolysis; Proteins; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry; Water

1991
[Chemical modification of lysine residues in tyrosyl-tRNA-synthetase from cattle liver using pyridoxal-5'-phosphate].
    Biokhimiia (Moscow, Russia), 1991, Volume: 56, Issue:11

    Topics: Animals; Cattle; Hydrolysis; Kinetics; Lysine; Molecular Weight; Pyridoxal Phosphate; Substrate Specificity; Tyrosine-tRNA Ligase

1991
Active site lysine promotes catalytic function of pyridoxal 5'-phosphate in alpha-glucan phosphorylases.
    The Journal of biological chemistry, 1991, May-25, Volume: 266, Issue:15

    Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cations; Escherichia coli; Glucosyltransferases; Kinetics; Lysine; Molecular Sequence Data; Mutation; Phosphorylases; Pyridoxal Phosphate

1991
Inactivation of chloroplast H(+)-ATPase by modification of Lys beta 359, Lys alpha 176 and Lys alpha 266.
    European journal of biochemistry, 1991, Sep-01, Volume: 200, Issue:2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Calcium-Transporting ATPases; Catalysis; Chloroplasts; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrolysis; Lysine; Magnesium; Molecular Sequence Data; Proton-Translocating ATPases; Pyridoxal Phosphate

1991
4-Aminobutyrate aminotransferase: identification of lysine residues connected with catalytic activity.
    Biochimica et biophysica acta, 1991, Apr-08, Volume: 1077, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Animals; Catalysis; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Lysine; Oxidation-Reduction; Pyridoxal Phosphate; Spectrum Analysis; Swine; Trypsin

1991
Characterization of the half and overall reactions catalyzed by L-lysine:2-oxoglutarate 6-aminotransferase.
    Journal of biochemistry, 1991, Volume: 109, Issue:1

    Topics: Binding Sites; Flavobacterium; Kinetics; L-Lysine 6-Transaminase; Lysine; Pyridoxal Phosphate; Substrate Specificity; Transaminases

1991
The adenine nucleotide-binding site on yeast 3-phosphoglycerate kinase. Affinity labeling of Lys-131 by pyridoxal 5'-diphospho-5'-adenosine.
    The Journal of biological chemistry, 1991, Apr-15, Volume: 266, Issue:11

    Topics: Adenosine Diphosphate; Affinity Labels; Amino Acid Sequence; Binding Sites; Computer Graphics; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Phosphoglycerate Kinase; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid

1991
Effect of substitution of a lysyl residue that binds pyridoxal phosphate in thermostable D-amino acid aminotransferase by arginine and alanine.
    Biochemistry, 1991, Apr-23, Volume: 30, Issue:16

    Topics: Alanine; Alanine Transaminase; Arginine; Base Sequence; Cloning, Molecular; D-Alanine Transaminase; Enzyme Stability; Escherichia coli; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Plasmids; Pyridoxal Phosphate; Recombinant Proteins; Restriction Mapping; Spectrophotometry; Thermodynamics

1991
Topological dispositions of lysine alpha 380 and lysine gamma 486 in the acetylcholine receptor from Torpedo californica.
    Biochemistry, 1991, Apr-23, Volume: 30, Issue:16

    Topics: Amino Acid Sequence; Animals; Binding Sites; Borohydrides; Bungarotoxins; Cell Membrane; Electric Organ; Lysine; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Pyridoxal Phosphate; Receptors, Nicotinic; Saponins; Torpedo

1991
Measurement of exofacially reactive lysines on human erythrocyte band 3 using pyridoxal 5'-phosphate.
    The Journal of membrane biology, 1991, Volume: 121, Issue:1

    Topics: Anion Exchange Protein 1, Erythrocyte; Erythrocyte Membrane; Humans; Lysine; Pyridoxal Phosphate

1991
Identification of lysyl residues located at the substrate-binding site in UDP-glucose pyrophosphorylase from potato tuber: affinity labeling with uridine di- and triphosphopyridoxals.
    Biochemistry, 1991, Sep-03, Volume: 30, Issue:35

    Topics: Affinity Labels; Amino Acid Sequence; Binding Sites; Enzyme Activation; Lysine; Molecular Sequence Data; Pyridoxal Phosphate; Solanum tuberosum; Substrate Specificity; Uridine Diphosphate; Uridine Triphosphate; UTP-Glucose-1-Phosphate Uridylyltransferase

1991
An active-site lysine in avian liver phosphoenolpyruvate carboxykinase.
    Biochemistry, 1991, Sep-10, Volume: 30, Issue:36

    Topics: Animals; Binding Sites; Chickens; Circular Dichroism; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Liver; Lysine; Manganese; Phosphoenolpyruvate Carboxykinase (GTP); Protein Conformation; Pyridoxal Phosphate; Substrate Specificity

1991
Possible involvement of Lys603 from Escherichia coli glucosamine-6-phosphate synthase in the binding of its substrate fructose 6-phosphate.
    European journal of biochemistry, 1991, Oct-01, Volume: 201, Issue:1

    Topics: Amino Acid Sequence; Binding Sites; Borohydrides; Cyanides; Escherichia coli; Fructosephosphates; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Kinetics; Lysine; Molecular Sequence Data; Peptide Mapping; Peptides; Potassium Cyanide; Pyridoxal Phosphate

1991
2-Amino-3-ketobutyrate CoA ligase of Escherichia coli: stoichiometry of pyridoxal phosphate binding and location of the pyridoxyllysine peptide in the primary structure of the enzyme.
    Biochimica et biophysica acta, 1990, Jan-19, Volume: 1037, Issue:1

    Topics: Acetyltransferases; Amino Acid Sequence; Amino Acids; Binding Sites; Escherichia coli; Lysine; Molecular Sequence Data; Peptide Mapping; Pyridoxal Phosphate; Trypsin

1990
Aspartate aminotransferase with the pyridoxal-5'-phosphate-binding lysine residue replaced by histidine retains partial catalytic competence.
    European journal of biochemistry, 1990, Jan-26, Volume: 187, Issue:2

    Topics: Animals; Aspartate Aminotransferases; Binding Sites; Binding, Competitive; Catalysis; Chickens; Circular Dichroism; Escherichia coli; Gene Expression Regulation, Enzymologic; Histidine; Lysine; Mutation; Plasmids; Protein Engineering; Pyridoxal Phosphate; Recombinant Proteins

1990
The cosubstrate NADP(H) protects lysine 601 in the porcine NADPH-cytochrome P-450 reductase against pyridoxylation.
    FEBS letters, 1990, Jan-29, Volume: 260, Issue:2

    Topics: Alkylation; Animals; Binding Sites; Chromatography, High Pressure Liquid; Liver; Lysine; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Pyridoxal Phosphate; Substrate Specificity; Swine

1990
Chemical modification of adenylosuccinate synthetase from Escherichia coli by pyridoxal 5'-phosphate. Identification of an active site lysyl residue.
    The Journal of biological chemistry, 1990, Apr-15, Volume: 265, Issue:11

    Topics: Adenylosuccinate Synthase; Amino Acid Sequence; Binding Sites; Escherichia coli; Kinetics; Ligases; Lysine; Molecular Sequence Data; Peptide Mapping; Pyridoxal Phosphate

1990
Chemical modification by pyridoxal 5'-phosphate and cyclohexane-1,2-dione indicates that Lys-7 and Arg-10 are involved in the p2 phosphate-binding subsite of bovine pancreatic ribonuclease A.
    The Biochemical journal, 1990, May-01, Volume: 267, Issue:3

    Topics: Animals; Arginine; Binding Sites; Cattle; Cyclohexanes; Cyclohexanones; Lysine; Phosphates; Pyridoxal Phosphate; Ribonuclease, Pancreatic

1990
Enhancement of aldose reductase activity by modification of an active site lysine: a possible mechanism for in vivo activation.
    Advances in enzyme regulation, 1990, Volume: 30

    Topics: Aldehyde Reductase; Amino Acid Sequence; Animals; Binding Sites; Enzyme Activation; Humans; Kinetics; Lysine; Molecular Sequence Data; Muscles; Peptide Fragments; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid; Substrate Specificity; Sugar Alcohol Dehydrogenases; Swine

1990
Substitution of glutamine for lysine at the pyridoxal phosphate binding site of bacterial D-amino acid transaminase. Effects of exogenous amines on the slow formation of intermediates.
    The Journal of biological chemistry, 1990, Dec-25, Volume: 265, Issue:36

    Topics: Base Sequence; Binding Sites; Circular Dichroism; D-Alanine Transaminase; Escherichia coli; Glutamine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Transaminases

1990
Lysine 480 is an essential residue in the putative ATP site of lamb kidney (Na,K)-ATPase. Identification of the pyridoxal 5'-diphospho-5'-adenosine and pyridoxal phosphate reactive residue.
    The Journal of biological chemistry, 1990, Jun-25, Volume: 265, Issue:18

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; Kidney; Kinetics; Lysine; Models, Structural; Molecular Sequence Data; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid; Sheep; Sodium-Potassium-Exchanging ATPase

1990
Characterization of the ATP binding site on Escherichia coli DNA gyrase. Affinity labeling of Lys-103 and Lys-110 of the B subunit by pyridoxal 5'-diphospho-5'-adenosine.
    The Journal of biological chemistry, 1990, Dec-05, Volume: 265, Issue:34

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; DNA Topoisomerases, Type II; Escherichia coli; Kinetics; Lysine; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid

1990
Labeling of specific lysine residues at the active site of glutamine synthetase.
    The Journal of biological chemistry, 1985, Dec-05, Volume: 260, Issue:28

    Topics: Adenosine; Adenosine Triphosphate; Amino Acids; Binding Sites; Escherichia coli; Glutamate-Ammonia Ligase; Glutamine; Homoarginine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mathematics; Methionine Sulfoximine; Pyridoxal Phosphate; Spectrometry, Fluorescence; Thiourea

1985
Substrate binding domain of murine leukemia virus reverse transcriptase. Identification of lysine 103 and lysine 421 as binding site residues.
    The Journal of biological chemistry, 1988, Feb-05, Volume: 263, Issue:4

    Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Deoxyribonucleosides; Endoribonucleases; Lysine; Mice; Moloney murine leukemia virus; Peptide Mapping; Pyridoxal Phosphate; Ribonuclease H; RNA-Directed DNA Polymerase

1988
Substrate binding in human immunodeficiency virus reverse transcriptase. An analysis of pyridoxal 5'-phosphate sensitivity and identification of lysine 263 in the substrate-binding domain.
    The Journal of biological chemistry, 1989, May-25, Volume: 264, Issue:15

    Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Endoribonucleases; Escherichia coli; HIV; Kinetics; Lysine; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Pyridoxal Phosphate; Ribonuclease H; RNA-Directed DNA Polymerase

1989
The beta subunit of tryptophan synthase. Clarification of the roles of histidine 86, lysine 87, arginine 148, cysteine 170, and cysteine 230.
    The Journal of biological chemistry, 1989, Apr-15, Volume: 264, Issue:11

    Topics: Arginine; Binding Sites; Cloning, Molecular; Cysteine; DNA Mutational Analysis; Histidine; Lysine; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Spectrum Analysis; Tryptophan Synthase

1989
Cytoprotective value of lysine, penicillamine, and pyridoxal phosphate against the neurotoxicity of acetaldehyde.
    Toxicology and applied pharmacology, 1989, Volume: 98, Issue:3

    Topics: Acetaldehyde; Animals; Brain; Lysine; Male; Penicillamine; Pyridoxal Phosphate; Rats; Rats, Inbred Strains

1989
Active-site modification of mammalian DNA polymerase beta with pyridoxal 5'-phosphate: mechanism of inhibition and identification of lysine 71 in the deoxynucleoside triphosphate binding pocket.
    Biochemistry, 1989, Jul-25, Volume: 28, Issue:15

    Topics: Amino Acid Sequence; Animals; Binding Sites; Deoxyribonucleotides; DNA Polymerase I; DNA Replication; Escherichia coli; Kinetics; Lysine; Molecular Sequence Data; Peptide Fragments; Protein Binding; Pyridoxal Phosphate; Rats; Recombinant Proteins; Templates, Genetic; Trypsin

1989
Structural and functional properties of human alpha-thrombin, phosphopyridoxylated alpha-thrombin, and gamma T-thrombin. Identification of lysyl residues in alpha-thrombin that are critical for heparin and fibrin(ogen) interactions.
    The Journal of biological chemistry, 1989, Nov-05, Volume: 264, Issue:31

    Topics: Antibodies, Monoclonal; Antithrombin III; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Fibrin; Fibrinogen; Heparin; Humans; Immunoassay; Lysine; Peptide Fragments; Pyridoxal Phosphate; Structure-Activity Relationship; Thrombin

1989
Evidence that pyridoxal phosphate modification of lysine residues (Lys-55 and Lys-59) causes inactivation of hydroxymethylbilane synthase (porphobilinogen deaminase).
    The Biochemical journal, 1989, Aug-15, Volume: 262, Issue:1

    Topics: Amino Acid Sequence; Ammonia-Lyases; Binding Sites; Escherichia coli; Hydroxymethylbilane Synthase; Lysine; Plasmids; Protease Inhibitors; Pyridoxal Phosphate

1989
2.8-A-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli.
    Biochemistry, 1989, Oct-03, Volume: 28, Issue:20

    Topics: Aspartate Aminotransferases; Binding Sites; Crystallization; Escherichia coli; Lysine; Mutation; Protein Conformation; Pyridoxal Phosphate; Schiff Bases; X-Ray Diffraction

1989
Pig gastric (H+ + K+)-ATPase. Lys-497 conserved in cation transporting ATPases is modified with pyridoxal 5'-phosphate.
    The Journal of biological chemistry, 1989, May-25, Volume: 264, Issue:15

    Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; Enzyme Activation; Gastric Mucosa; Gastrointestinal Hormones; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Pyridoxal Phosphate; Swine

1989
Energy-dependent conformational changes in the epsilon subunit of the chloroplast ATP synthase (CF0CF1).
    The Journal of biological chemistry, 1989, Oct-25, Volume: 264, Issue:30

    Topics: Amino Acid Sequence; Chloroplasts; Energy Transfer; Lysine; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Plants; Protein Conformation; Proton-Translocating ATPases; Pyridoxal Phosphate; Spectrometry, Fluorescence

1989
The modification of essential lysine residues for actin binding of myosin subfragment-1 by pyridoxal-5'-phosphate.
    Acta biochimica et biophysica Hungarica, 1989, Volume: 24, Issue:4

    Topics: Actins; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Electrophoresis, Polyacrylamide Gel; Kinetics; Lysine; Myosin Subfragments; Protein Binding; Pyridoxal Phosphate; Rabbits; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid

1989
Further characterization of the binding of plasminogen to heparin: evidence for the involvement of lysine residues.
    Biochimica et biophysica acta, 1989, Nov-09, Volume: 999, Issue:1

    Topics: Binding Sites; Borohydrides; Chemical Phenomena; Chemistry; Fibrinolysin; Glutamates; Glutamic Acid; Heparin; Humans; Lysine; Plasminogen; Pyridoxal Phosphate; Valine

1989
Inactivation of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii by pyridoxal 5'-phosphate. Determination of the pH dependence of enzyme-reactant dissociation constants from protection against inactivation.
    The Journal of biological chemistry, 1988, Apr-15, Volume: 263, Issue:11

    Topics: Algorithms; Diphosphates; Fructosephosphates; Hydrogen-Ion Concentration; Kinetics; Lysine; Phosphofructokinase-1; Propionibacterium; Pyridoxal Phosphate

1988
Pyridoxal 5'-diphospho-5'-adenosine binds at a single site on isolated alpha-subunit from Escherichia coli F1-ATPase and specifically reacts with lysine 201.
    The Journal of biological chemistry, 1988, Apr-25, Volume: 263, Issue:12

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Binding, Competitive; Borohydrides; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Lysine; Macromolecular Substances; Molecular Sequence Data; Protein Conformation; Proton-Translocating ATPases; Pyridoxal Phosphate; Trypsin

1988
Site-directed mutagenesis of Petunia hybrida 5-enolpyruvylshikimate-3-phosphate synthase: Lys-23 is essential for substrate binding.
    The Journal of biological chemistry, 1988, Aug-25, Volume: 263, Issue:24

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alanine; Alkyl and Aryl Transferases; Arginine; Binding Sites; Binding, Competitive; Glutamates; Glutamic Acid; Glycine; Glyphosate; Herbicides; Lysine; Mutation; Phosphoenolpyruvate; Plants; Pyridoxal Phosphate; Shikimic Acid; Transferases

1988
Effect of modification of lysine residues of fructose-6-phosphate 2-kinase:fructose-2,6-bisphosphatase with pyridoxal 5'-phosphate.
    The Journal of biological chemistry, 1985, Nov-15, Volume: 260, Issue:26

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding, Competitive; Borohydrides; Chemical Phenomena; Chemistry; Fructosediphosphates; Fructosephosphates; Kinetics; Liver; Lysine; Oxidation-Reduction; Peptide Fragments; Phosphofructokinase-2; Phosphoric Monoester Hydrolases; Phosphotransferases; Pyridoxal Phosphate; Rats; Trypsin

1985
X-ray studies of nucleotide binding and pyridoxal phosphate labeling of the gene 5 DNA unwinding protein.
    Biochimica et biophysica acta, 1986, Apr-22, Volume: 870, Issue:3

    Topics: Adamantane; Affinity Labels; Bacteriophages; Binding Sites; Deoxycytidine Monophosphate; DNA Helicases; Fourier Analysis; Lysine; Models, Molecular; Nucleotides; Pyridoxal Phosphate; Thymidine Monophosphate; X-Ray Diffraction

1986
The transmembrane arrangement of the ADP/ATP carrier as elucidated by the lysine reagent pyridoxal 5-phosphate.
    European journal of biochemistry, 1986, Dec-15, Volume: 161, Issue:3

    Topics: Animals; Base Sequence; Borohydrides; Cattle; Chromatography, High Pressure Liquid; Cytosol; Detergents; Lysine; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Nucleotidyltransferases; Peptide Mapping; Protein Binding; Pyridoxal Phosphate

1986
Affinity labeling of adenylate kinase with adenosine diphosphopyridoxal. Presence of Lys21 in the ATP-binding site.
    The Journal of biological chemistry, 1987, Jun-15, Volume: 262, Issue:17

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Affinity Labels; Animals; Binding Sites; Kinetics; Lysine; Muscles; Phosphotransferases; Protein Binding; Pyridoxal Phosphate; Rabbits

1987
[Functionally important lysine residues in inorganic pyrophosphatase from E. coli. I. Interaction of inorganic pyrophosphatase with pyridoxal-5'-phosphate].
    Bioorganicheskaia khimiia, 1987, Volume: 13, Issue:5

    Topics: Binding Sites; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Inorganic Pyrophosphatase; Kinetics; Lysine; Pyridoxal Phosphate; Pyrophosphatases

1987
[Functionally important lysine residues in inorganic pyrophosphatase from E. coli. II. Isolation and characteristics of modified tryptic peptide and analysis of the functional role of lysine residues controlling enzyme activity].
    Bioorganicheskaia khimiia, 1987, Volume: 13, Issue:5

    Topics: Amino Acid Sequence; Binding Sites; Calcium; Calcium Pyrophosphate; Escherichia coli; Hydrolysis; Inorganic Pyrophosphatase; Kinetics; Lysine; Macromolecular Substances; Oligopeptides; Pyridoxal Phosphate; Pyrophosphatases

1987
Modification of an essential amino group of phosphoenolpyruvate carboxylase from maize leaves by pyridoxal phosphate and by pyridoxal phosphate-sensitized photooxidation.
    Archives of biochemistry and biophysics, 1986, May-01, Volume: 246, Issue:2

    Topics: Binding Sites; Carboxy-Lyases; Catalysis; Lysine; Models, Chemical; Oxidation-Reduction; Phosphoenolpyruvate Carboxylase; Photochemistry; Pyridoxal Phosphate; Zea mays

1986
Stereospecificity of sodium borohydride reduction of pig kidney dopa decarboxylase.
    Archives of biochemistry and biophysics, 1986, Volume: 251, Issue:2

    Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Borohydrides; Chromatography, High Pressure Liquid; Dopa Decarboxylase; Kidney; Lysine; Molecular Conformation; Oxidation-Reduction; Pyridoxal; Pyridoxal Phosphate; Schiff Bases; Swine

1986
Purification and active site modification studies on glyoxalase I from monkey intestinal mucosa.
    Biochimica et biophysica acta, 1987, Jul-07, Volume: 913, Issue:3

    Topics: Amino Acids, Dicarboxylic; Animals; Anions; Apoproteins; Binding Sites; Cations; Intestinal Mucosa; Lactoylglutathione Lyase; Lyases; Lysine; Macaca radiata; Molecular Weight; Pyridoxal Phosphate; Structure-Activity Relationship; Sulfhydryl Compounds; Tryptophan; Tyrosine

1987
Identification of a lysyl residue in antithrombin which is essential for heparin binding.
    The Journal of biological chemistry, 1987, Jun-15, Volume: 262, Issue:17

    Topics: Amino Acid Sequence; Antithrombins; Binding Sites; Heparin; Humans; Lysine; Peptide Mapping; Protein Binding; Pyridoxal Phosphate; Trypsin

1987
Substitution of an arginyl residue for the active site lysyl residue (Lys258) of aspartate aminotransferase.
    Biochemical and biophysical research communications, 1987, Jul-31, Volume: 146, Issue:2

    Topics: Amino Acid Sequence; Arginine; Aspartate Aminotransferases; Binding Sites; Circular Dichroism; Escherichia coli; Lysine; Mutation; Pyridoxal Phosphate; Spectrophotometry; Structure-Activity Relationship

1987
Brain pyridoxine-5-phosphate oxidase. Modulation of its catalytic activity by reaction with pyridoxal 5-phosphate and analogs.
    The Journal of biological chemistry, 1987, Sep-05, Volume: 262, Issue:25

    Topics: Amino Acid Sequence; Animals; Brain; Flavin Mononucleotide; Kinetics; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Peptide Mapping; Pyridoxal Phosphate; Pyridoxaminephosphate Oxidase; Sheep; Spectrophotometry

1987
Chemical modification of phenol hydroxylase by ethoxyformic anhydride.
    European journal of biochemistry, 1987, Dec-30, Volume: 170, Issue:1-2

    Topics: Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Lysine; Mathematics; Mixed Function Oxygenases; Pyridoxal Phosphate; Saccharomyces cerevisiae; Spectrophotometry

1987
Human erythrocyte glucose-6-phosphate dehydrogenase. Identification of a reactive lysyl residue labelled with pyridoxal 5'-phosphate.
    European journal of biochemistry, 1988, Feb-01, Volume: 171, Issue:3

    Topics: Affinity Labels; Amino Acid Sequence; Amino Acids; Binding Sites; Erythrocytes; Glucosephosphate Dehydrogenase; Humans; Hydrolysis; Lysine; Peptides; Pyridoxal Phosphate; Trypsin

1988
The adenine nucleotide binding site on yeast hexokinase PII. Affinity labeling of Lys-111 by pyridoxal 5'-diphospho-5'-adenosine.
    The Journal of biological chemistry, 1988, Jun-05, Volume: 263, Issue:16

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Binding, Competitive; Computer Simulation; Hexokinase; Isoenzymes; Kinetics; Lysine; Pyridoxal Phosphate

1988
Catalytic site of rabbit glycogen synthase isozymes. Identification of an active site lysine close to the amino terminus of the subunit.
    The Journal of biological chemistry, 1988, Aug-05, Volume: 263, Issue:22

    Topics: Amino Acid Sequence; Animals; Binding Sites; Borohydrides; Glycogen Synthase; Isoenzymes; Kinetics; Liver; Lysine; Molecular Sequence Data; Muscles; Organ Specificity; Peptide Fragments; Pyridoxal Phosphate; Rabbits; Trypsin

1988
Fluorescence resonance energy transfer studies on the proximity between lysine-107 and cysteine-239 in rabbit muscle aldolase.
    Biochimica et biophysica acta, 1988, Oct-12, Volume: 956, Issue:3

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cysteine; Energy Transfer; Fructose-Bisphosphate Aldolase; Lysine; Muscles; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Pyridoxamine; Rabbits; Spectrometry, Fluorescence

1988
Evidence for the extramembranous location of the putative amphipathic helix of acetylcholine receptor.
    Biochemistry, 1988, Jul-26, Volume: 27, Issue:15

    Topics: Animals; Imidoesters; Immunologic Techniques; Lysine; Membrane Proteins; Neuromuscular Junction; Oligopeptides; Protein Conformation; Pyridoxal Phosphate; Receptors, Nicotinic; Torpedo

1988
Inactivation of yeast hexokinase by o-phthalaldehyde: evidence for the presence of a cysteine and a lysine at or near the active site.
    Biochimica et biophysica acta, 1988, Nov-02, Volume: 957, Issue:1

    Topics: Aldehydes; Binding Sites; Chelating Agents; Chemical Phenomena; Chemistry; Cysteine; Hexokinase; Kinetics; Lysine; Nucleosides; Nucleotides; o-Phthalaldehyde; Pyridoxal Phosphate; Saccharomyces cerevisiae; Structure-Activity Relationship

1988
Pyridoxal 5'-phosphate mediated inactivation of Escherichia coli DNA polymerase I: identification of lysine-635 as an essential residue for the processive mode of DNA synthesis.
    Biochemistry, 1988, Sep-06, Volume: 27, Issue:18

    Topics: Binding Sites; DNA Polymerase I; DNA, Bacterial; Escherichia coli; Kinetics; Lysine; Peptide Fragments; Pyridoxal Phosphate; Trypsin; Ultraviolet Rays

1988
The ATP binding site on rho protein. Affinity labeling of Lys181 by pyridoxal 5'-diphospho-5'-adenosine.
    The Journal of biological chemistry, 1988, Dec-15, Volume: 263, Issue:35

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; Lysine; Molecular Sequence Data; Poly C; Pyridoxal Phosphate; Rho Factor; Transcription Factors

1988
Nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase of Neurospora. I. Isolation, subunits, amino acid composition, sulfhydryl groups, and identification of a lysine residue reactive with pyridoxal phosphate and N-ethylmaleimide.
    The Journal of biological chemistry, 1973, Sep-10, Volume: 248, Issue:17

    Topics: Amino Acids; Ammonium Sulfate; Binding Sites; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; Glutamate Dehydrogenase; Lysine; Macromolecular Substances; Mathematics; Molecular Weight; NADP; Neurospora; Peptides; Pyridoxal Phosphate; Sulfhydryl Compounds; Sulfhydryl Reagents; Thermodynamics; Trypsin; Ultracentrifugation

1973
Chemical properties of Escherichia coli lysine decarboxylase including a segment of its pyridoxal 5'-phosphate binding site.
    Biochemistry, 1974, Feb-12, Volume: 13, Issue:4

    Topics: Amino Acid Sequence; Amino Acids; Arginine; Binding Sites; Carboxy-Lyases; Chymotrypsin; Cross Reactions; Enzyme Activation; Enzyme Induction; Escherichia coli; Freeze Drying; Glutamates; Immunodiffusion; Lysine; Peptide Fragments; Protein Binding; Protein Denaturation; Pyridoxal Phosphate; Sulfhydryl Compounds; Thermolysin

1974
Cofactor investigation of bovine plasma amine oxidase. NaBH4 reduction of enzyme-substrate mixture.
    The Journal of biological chemistry, 1974, Aug-25, Volume: 249, Issue:16

    Topics: Amine Oxidase (Copper-Containing); Amino Acids; Animals; Benzyl Compounds; Binding Sites; Borohydrides; Carbon Radioisotopes; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Hydrogen-Ion Concentration; Kinetics; Lysine; Mass Spectrometry; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet

1974
Regulation of rat liver glycogen synthetase. Evidence for a lysyl residue essential for glucose 6-phosphate activation.
    The Journal of biological chemistry, 1974, Nov-10, Volume: 249, Issue:21

    Topics: Animals; Benzenesulfonates; Binding Sites; Borohydrides; Carbon Radioisotopes; Enzyme Activation; Glucosephosphates; Glycogen Synthase; Kinetics; Liver; Lysine; Molecular Weight; Nitrophenols; Organophosphorus Compounds; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Pyridoxamine; Rats; Schiff Bases; Spectrophotometry, Ultraviolet

1974
Studies on heart phosphofructokinase. The effect of pyridoxal 5'-phosphate on enzyme activity and dissociation.
    Biochimica et biophysica acta, 1972, Jan-20, Volume: 258, Issue:1

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Allosteric Regulation; Animals; Borohydrides; Centrifugation, Density Gradient; Citrates; Fructosephosphates; Hydrogen-Ion Concentration; Lysine; Macromolecular Substances; Myocardium; Oxidation-Reduction; Phosphofructokinase-1; Protein Binding; Pyridoxal Phosphate; Schiff Bases; Sheep; Spectrophotometry; Temperature; Ultraviolet Rays

1972
The effects of pyridoxal phosphate on rabbit liver and kidney fructose 1,6-diphosphatases.
    Archives of biochemistry and biophysics, 1969, Volume: 132, Issue:1

    Topics: Adenine Nucleotides; Amines; Amino Acids; Animals; Boron Compounds; Fructose-Bisphosphatase; Kidney; Liver; Lysine; Molecular Weight; Nitrogen; Phosphates; Pyridines; Pyridoxal Phosphate; Rabbits; Radioisotopes; Spectrum Analysis

1969
The effect of pyridoxal phosphate modification on the catalytic and regulatory properties of bovine liver glutamate dehydrogenase.
    The Journal of biological chemistry, 1972, Apr-10, Volume: 247, Issue:7

    Topics: Amino Acid Sequence; Animals; Catalysis; Cattle; Enzyme Activation; Glutamate Dehydrogenase; Guanosine Triphosphate; Kinetics; Liver; Lysine; Macromolecular Substances; NAD; Nitrobenzenes; Peptides; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Sulfonic Acids

1972
Selective alteration of the regulatory properties of fructose 1,6-diphosphatase by modification with pyridoxal 5'-phosphate.
    Biochemistry, 1972, May-09, Volume: 11, Issue:10

    Topics: Adenosine Diphosphate; Allosteric Regulation; Ammonium Sulfate; Animals; Binding Sites; Borohydrides; Carbon Isotopes; Catalysis; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Enzyme Activation; Fructose-Bisphosphatase; Fructosephosphates; Hot Temperature; Kidney; Lysine; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Swine

1972
The lysines in liver alcohol dehydrogenase. Chemical modification with pyridoxal 5'-phosphate and methyl picolinimidate.
    European journal of biochemistry, 1972, Jun-23, Volume: 28, Issue:1

    Topics: Adenosine Monophosphate; Alcohol Oxidoreductases; Animals; Binding Sites; Borohydrides; Chemical Phenomena; Chemistry; Horses; Hydrogen-Ion Concentration; Imides; Imidoesters; Kinetics; Liver; Lysine; NAD; Osmolar Concentration; Oxidation-Reduction; Picolinic Acids; Pyridoxal Phosphate; Zinc

1972
Studies of glutamate dehydrogenase. Characterization of histidine residues involved in the activity and association. Photoactivated labelling with pyridoxal 5'-phosphate.
    European journal of biochemistry, 1973, Jan-03, Volume: 32, Issue:1

    Topics: Adenosine Diphosphate; Amino Acids; Binding Sites; Carbonates; Diphosphates; Enzyme Activation; Glutamate Dehydrogenase; Guanosine Triphosphate; Histidine; Imidazoles; Light; Lysine; NAD; Photochemistry; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry, Ultraviolet; Tritium

1973
The effect of modifying lysine-126 on the physical, catalytic and regulatory properties of bovine liver glutamate dehydrogenase.
    The Biochemical journal, 1973, Volume: 133, Issue:1

    Topics: Adenosine Diphosphate; Amides; Animals; Binding Sites; Carbon Isotopes; Cattle; Chromatography, Gel; Glutamate Dehydrogenase; Guanosine Triphosphate; Hydrogen-Ion Concentration; Iodoacetates; Ketoglutaric Acids; Kinetics; Liver; Lysine; NAD; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Salicylates; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sulfites; Time Factors; Ultracentrifugation

1973
Modification of fructose-1,6-diphosphatase with pyridoxal 5'-phosphate. Evidence for the participation of lysyl residues at the active site.
    Biochemistry, 1974, Jul-16, Volume: 13, Issue:15

    Topics: Adenosine Monophosphate; Allosteric Regulation; Animals; Binding Sites; Borohydrides; Chromatography, Gel; Chromatography, Paper; Fructose-Bisphosphatase; Fructosephosphates; Glycerophosphates; Hexosediphosphates; Hydrogen-Ion Concentration; Kidney; Kinetics; Lysine; Oxidation-Reduction; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Swine

1974
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. III. Isolation and sequences of peptides containing selectively labeled lysine and cysteine residues.
    The Journal of biological chemistry, 1974, Dec-25, Volume: 249, Issue:24

    Topics: Amino Acid Sequence; Amino Acids; Aminopeptidases; Binding Sites; Borohydrides; Carbon Radioisotopes; Carboxypeptidases; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Cysteine; Electrophoresis, Paper; Ethylmaleimide; Glutamate Dehydrogenase; Leucyl Aminopeptidase; Lysine; NAD; Neurospora; Neurospora crassa; Oxidation-Reduction; Papain; Peptide Fragments; Protein Binding; Pyridoxal Phosphate; Thermolysin; Trypsin

1974
A modification of D-amino acid oxidase apoenzyme by pyridoxal 5'-phosphate.
    Biochimica et biophysica acta, 1970, Mar-18, Volume: 198, Issue:3

    Topics: Alanine; Animals; Boron Compounds; Chemical Phenomena; Chemistry; D-Amino-Acid Oxidase; Flavin-Adenine Dinucleotide; Kidney; Kinetics; Lysine; Pyridoxal Phosphate; Spectrophotometry; Swine

1970
The degradation of hydroxy-L-lysine in liver via its phosphate ester.
    Biochemical and biophysical research communications, 1970, Nov-09, Volume: 41, Issue:3

    Topics: Adenosine Triphosphate; Adipates; Aldehydes; Amino Acids; Animals; Esters; Guanine Nucleotides; Liver; Lysine; Male; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Rats; Stereoisomerism

1970
Glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides. Kinetic studies.
    The Journal of biological chemistry, 1971, Apr-10, Volume: 246, Issue:7

    Topics: Aldehydes; Chemical Phenomena; Chemistry; Glucosephosphate Dehydrogenase; Hexosephosphates; Hydrogen-Ion Concentration; Isomerism; Kinetics; Leuconostoc; Lysine; NAD; NADP; Picolines; Protein Binding; Pyridoxal Phosphate

1971
Bovine liver glutamate dehydrogenase. Equilibria and kinetics of imine formation by lysine-97 with pyridoxal 5'-phosphate.
    Biochemistry, 1971, Nov-23, Volume: 10, Issue:24

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Imines; Kinetics; Liver; Lysine; Mathematics; Models, Biological; Models, Structural; NAD; NADP; Protein Binding; Pyridoxal Phosphate

1971
Chemical modification of the lysine-amino groups of potato virus X.
    The Journal of general virology, 1974, Volume: 25, Issue:2

    Topics: Benzenesulfonates; Cytopathogenic Effect, Viral; Dansyl Compounds; Electrophoresis; Imides; Indicators and Reagents; Lysine; Nitro Compounds; Picolinic Acids; Plant Viruses; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrum Analysis; Viral Proteins

1974
Modification of pepsinogen with pyridoxal phosphate.
    The Journal of biological chemistry, 1974, Dec-10, Volume: 249, Issue:23

    Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Disc; Electrophoresis, Paper; Ethanol; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Molecular Weight; Optical Rotation; Pepsinogens; Peptide Fragments; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Swine; Temperature; Trypsin

1974
The decarboxylation of amino acids by bacteria derived from human dental plaque.
    Archives of oral biology, 1974, Volume: 19, Issue:5

    Topics: Amino Acids; Aspartic Acid; Bacteria; Carbon Dioxide; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Decarboxylation; Dental Plaque; Glutamates; Histidine; Humans; Hydrogen-Ion Concentration; Lysine; Ornithine; Pyridoxal Phosphate

1974
Regulation of biodegradative threonine deaminase. II. Reaction mechanism as analyzed by spectrophotometric properties.
    The Journal of biological chemistry, 1973, Jun-25, Volume: 248, Issue:12

    Topics: Butyrates; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Enzyme Activation; Escherichia coli; Hydro-Lyases; Keto Acids; Kinetics; Lysine; Mathematics; Models, Chemical; Protein Binding; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry; Spectrophotometry, Ultraviolet; Threonine

1973
Aspartate transcarbamylase from Escherichia coli. The use of pyridoxal 5'-phosphate as a probe in the active site.
    The Journal of biological chemistry, 1973, Sep-10, Volume: 248, Issue:17

    Topics: Amino Acids; Aspartate Carbamoyltransferase; Binding Sites; Borohydrides; Carbon Isotopes; Chemical Phenomena; Chemistry; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Light; Lysine; Macromolecular Substances; Oxidation-Reduction; Photochemistry; Pyridoxal; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry; Structure-Activity Relationship; Sulfhydryl Compounds

1973
Pyruvate carboxylase. Specific inactivation of acetyl coenzyme A-dependent oxylacetate synthesis during modification of the enzyme by trinitrobenzene sulfonate.
    The Journal of biological chemistry, 1973, Aug-10, Volume: 248, Issue:15

    Topics: Acetyl Coenzyme A; Animals; Benzenesulfonates; Binding Sites; Cyanates; Ethylmaleimide; Kinetics; Liver; Lysine; Nitrobenzenes; Oxaloacetates; Potassium Chloride; Protein Binding; Pyridoxal Phosphate; Pyruvate Carboxylase; Rats; Saccharomyces cerevisiae; Salicylates; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors

1973
Modification of ribonuclease A with pyridoxal-5'-phosphate.
    Molecular biology, 1974, Volume: 8, Issue:2

    Topics: Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cytosine Nucleotides; Kinetics; Lysine; Oxidation-Reduction; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Ribonucleases; RNA; Saccharomyces cerevisiae; Spectrophotometry; Spectrophotometry, Ultraviolet; Subtilisins; Trypsin

1974
5-(2-Chloroethyl)-3-hydroxy-2-methyl-4-pyridinecarboxaldehyde ( 5 -pyridoxal methyl chloride) and its reaction with N -acetyl-L-lysine to form a new cyclic imino acid derivative of homopyridoxal.
    Biochemistry, 1972, Dec-19, Volume: 11, Issue:26

    Topics: Acetates; Alkylation; Amino Acids; Chlorine; Cyclization; Hydrogen-Ion Concentration; Imines; Indicators and Reagents; Isomerism; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Naphthols; Picolines; Pyridoxal; Pyridoxal Phosphate; Pyridoxine; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet

1972
Paradoxical inhibition of phosphorylase by pyridoxal phosphate. 3. Sequence of amino acids at site of reaction.
    Canadian journal of biochemistry, 1973, Volume: 51, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Chromatography; Dansyl Compounds; Dialysis; Electrophoresis; Glucosyltransferases; Hydrolysis; Lysine; Muscles; Peptides; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1973
Mechanism of the gossypol inactivation of pepsinogen.
    The Journal of biological chemistry, 1973, Jul-10, Volume: 248, Issue:13

    Topics: Acetates; Amino Acids; Binding, Competitive; Borohydrides; Chemical Phenomena; Chemistry; Dansyl Compounds; Drug Stability; Ethanol; Gossypol; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Oxidation-Reduction; Pepsinogens; Protein Conformation; Pyridoxal Phosphate; Schiff Bases; Temperature

1973
Properties of chick tropoelastin.
    Biochimica et biophysica acta, 1973, Jul-12, Volume: 317, Issue:1

    Topics: Amino Acids; Animals; Aorta; Chickens; Cholesterol; Circular Dichroism; Copper; Deficiency Diseases; Elastin; Lysine; Pancreatic Elastase; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Precursors; Pyridoxal Phosphate; Schiff Bases; Sodium Dodecyl Sulfate; Solubility; Temperature

1973
The pyridoxal phosphate-binding site of rabbit muscle aldolase.
    Archives of biochemistry and biophysics, 1973, Volume: 156, Issue:2

    Topics: Alkylation; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Borohydrides; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Electrophoresis, Paper; Fructose-Bisphosphate Aldolase; Hydrazines; Lysine; Muscles; Oxidation-Reduction; Peptides; Protein Binding; Pyridoxal Phosphate; Rabbits; Schiff Bases; Thermolysin; Thiocyanates; Tritium; Trypsin

1973
The isolation and partial characterization of ribonuclease A from Bison bison.
    The Biochemical journal, 1973, Volume: 135, Issue:3

    Topics: Amino Acid Sequence; Ammonium Sulfate; Animals; Artiodactyla; Binding Sites; Buffers; Cattle; Chromatography, Affinity; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis; Hydrogen-Ion Concentration; Iodoacetates; Lysine; Methylhistidines; Oxidation-Reduction; Pancreas; Peptides; Phosphates; Piperazines; Pyridoxal Phosphate; Ribonucleases; Uracil Nucleotides

1973
Binding of pyridoxal 5-phosphate to cystathionase.
    The Journal of biological chemistry, 1973, Nov-10, Volume: 248, Issue:21

    Topics: Animals; Apoproteins; Binding Sites; Catalysis; Cystathionine; Dialysis; Homoserine; Liver; Lyases; Lysine; Macromolecular Substances; Mathematics; Models, Chemical; Protein Binding; Pyridoxal Phosphate; Rats; Spectrometry, Fluorescence; Spectrophotometry

1973
Characterization of two complementary polypeptide chains obtained by proteolysis of rabbit muscle phosphorylase.
    Biochemistry, 1973, Dec-04, Volume: 12, Issue:25

    Topics: Alkylation; Amino Acids; Animals; Binding Sites; Chemical Phenomena; Chemistry; Electrophoresis, Polyacrylamide Gel; Kinetics; Lysine; Macromolecular Substances; Molecular Weight; Muscles; Organophosphorus Compounds; Peptide Fragments; Phosphorus Radioisotopes; Phosphorylases; Protein Binding; Pyridoxal Phosphate; Rabbits; Serine; Sodium Dodecyl Sulfate; Solubility; Subtilisins; Trypsin

1973
Purification and properties of an amine oxidase in bovine dental pulp and its comparison with serum amine oxidase.
    Biochimica et biophysica acta, 1974, Apr-25, Volume: 341, Issue:2

    Topics: Aminopropionitrile; Animals; Antimetabolites; Chelating Agents; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclohexanes; Dental Pulp; Electrophoresis, Disc; Hydrazones; Hydrogen-Ion Concentration; Iproniazid; Kinetics; Lysine; Molecular Weight; Monoamine Oxidase; Organ Specificity; Pyridoxal Phosphate; Solubility; Spectrometry, Fluorescence; Structure-Activity Relationship; Vasopressins

1974
Effects of potassium iodide on aspartate aminotransferase.
    European journal of biochemistry, 1974, Feb-01, Volume: 41, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Binding Sites; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Iodides; Lysine; Mathematics; Myocardium; Potassium; Protein Binding; Pyridoxal; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine; Valine

1974
Studies of glutamate dehydrogenase. Identification of an amino group involved in the substrate binding.
    European journal of biochemistry, 1974, Feb-01, Volume: 41, Issue:3

    Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Borohydrides; Cattle; Electrophoresis, Paper; Glutamate Dehydrogenase; Glyoxal; Iodoacetates; Ketoglutaric Acids; Liver; Lysine; Peptide Fragments; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Salicylates; Tritium; Trypsin

1974
Argenine decarboxylase from Escherichia coli. I. Purification and specificity for substrates and coenzyme.
    The Journal of biological chemistry, 1968, Apr-25, Volume: 243, Issue:8

    Topics: Arginine; Binding Sites; Canavanine; Carboxy-Lyases; Chemical Precipitation; Chromatography, Ion Exchange; Crystallization; Cysteine; Dialysis; Electrophoresis, Disc; Escherichia coli; Guanidines; Hydrogen-Ion Concentration; Kinetics; Lysine; Protein Binding; Pyridoxal Phosphate; Spectrum Analysis; Temperature; Ultracentrifugation; Ultraviolet Rays

1968
Tyrosine phenol lyase. II. Cofactor requrements.
    The Journal of biological chemistry, 1970, Apr-10, Volume: 245, Issue:7

    Topics: Alanine; Amino Acids; Binding Sites; Boron Compounds; Chemical Phenomena; Chemistry; Chromatography, Paper; Dialysis; Electrophoresis; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Lysine; Phenols; Potassium; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Sodium; Spectrophotometry; Tyrosine; Ultraviolet Rays

1970
Some properties of Escherichia coli adenyl cyclase.
    Archives of biochemistry and biophysics, 1970, Volume: 141, Issue:1

    Topics: Acetates; Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Cell-Free System; Centrifugation, Density Gradient; Cytosine Nucleotides; Enzymes; Escherichia coli; Guanine Nucleotides; Kinetics; Lysine; Molecular Weight; Oxaloacetates; Pentosephosphates; Phosphorus Isotopes; Phosphotransferases; Pyridoxal Phosphate; Pyruvates; Tritium; Tromethamine; Uracil Nucleotides

1970
Mutants of Escherichia coli with a growth requirement for either lysine or pyridoxine.
    Journal of bacteriology, 1971, Volume: 105, Issue:3

    Topics: Amino Acids; Carboxy-Lyases; Cell-Free System; Centrifugation, Density Gradient; Centrifugation, Zonal; Chromosome Mapping; Colorimetry; Culture Media; Dialysis; Enzyme Activation; Escherichia coli; Genetics, Microbial; Lysine; Mutation; Pimelic Acids; Pyridoxal Phosphate; Pyridoxine; Saccharomyces; Spectrophotometry; Sucrose; Transduction, Genetic

1971
Arginine decarboxylase from Escherichia coli. IV. Structure of the pyridoxal phosphate binding site.
    The Journal of biological chemistry, 1971, Nov-25, Volume: 246, Issue:22

    Topics: Alkaline Phosphatase; Amino Acid Sequence; Amino Acids; Arginine; Autoanalysis; Binding Sites; Borohydrides; Carbon Isotopes; Carboxy-Lyases; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Dansyl Compounds; Escherichia coli; Fluorescence; Glutamates; Histidine; Lysine; Methods; Oxidation-Reduction; Peptides; Pyridoxal Phosphate; Schiff Bases; Thiocyanates; Trypsin

1971
Tryptophan synthetase 2 subunit. Primary structure of the pyridoxyl peptide from the Escherichia coli enzyme.
    The Journal of biological chemistry, 1971, Volume: 246, Issue:21

    Topics: Amino Acid Sequence; Amino Acids; Borohydrides; Carboxypeptidases; Chromatography, Ion Exchange; Dansyl Compounds; Electrophoresis, Paper; Escherichia coli; Formates; Glycerophosphates; Hydro-Lyases; Indoles; Lysine; Macromolecular Substances; Oxidation-Reduction; Peptides; Pyridoxal Phosphate; Serine; Tritium; Trypsin

1971
Further properties of the diamine oxidase of pea seedlings.
    The Biochemical journal, 1964, Volume: 91, Issue:1

    Topics: Amine Oxidase (Copper-Containing); Amines; Catalysis; Copper; Edetic Acid; Flavin-Adenine Dinucleotide; Hydrazines; In Vitro Techniques; Lysine; Ornithine; Phenanthrolines; Plants, Edible; Pyridoxal Phosphate

1964
Diaminopimelate decarboxylase of sporulating bacteria.
    Journal of bacteriology, 1968, Volume: 96, Issue:6

    Topics: Bacillus; Bacillus cereus; Carboxy-Lyases; Chromatography, Paper; Dimercaprol; Enzyme Repression; Lysine; Penicillamine; Picolinic Acids; Pimelic Acids; Pyridoxal Phosphate

1968
[Immunologic specificity of antibodies against pyridoxal and pyridoxal-5'-phosphate].
    Immunochemistry, 1970, Volume: 7, Issue:6

    Topics: Amines; Animals; Antibodies; Antigen-Antibody Reactions; Binding Sites; Cattle; Cross Reactions; Ethylamines; Haptens; Immunodiffusion; Lysine; Magnetic Resonance Spectroscopy; Methanol; Molecular Biology; Phosphates; Picolines; Pyridoxal Phosphate; Rabbits; Serum Albumin, Bovine; Urease

1970
Studies on the induction and repression of enzymes in rat liver. VI. Some properties and the metabolic regulation of two isozymic forms of serine dehydratase.
    The Journal of biological chemistry, 1971, Apr-25, Volume: 246, Issue:8

    Topics: Adrenal Glands; Adrenalectomy; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Chromatography, DEAE-Cellulose; Cortisone; Crystallization; Diabetes Mellitus, Experimental; Electrophoresis, Disc; Enzyme Induction; Glucagon; Hydro-Lyases; Immune Sera; Immunodiffusion; Isoenzymes; L-Serine Dehydratase; Leucine; Liver; Lysine; Male; Molecular Weight; Phosphates; Proline; Pyridoxal Phosphate; Rats; Spectrophotometry; Tritium; Ultraviolet Rays

1971
Comparison of the absorbance spectra and fluorescence behavior of phosphorylase b with that of model pyridoxal phosphate derivatives in various solvents.
    The Journal of biological chemistry, 1972, Feb-25, Volume: 247, Issue:4

    Topics: Amines; Animals; Buffers; Chemical Phenomena; Chemistry; Chloroform; Dioxins; Enzyme Activation; Esters; Glucosyltransferases; Hydrogen-Ion Concentration; Lysine; Methanol; Muscles; Phosphorylases; Pyridoxal Phosphate; Pyridoxamine; Rabbits; Schiff Bases; Spectrometry, Fluorescence; Structure-Activity Relationship; Ultraviolet Rays

1972
The role of pyridoxal phosphate in the B 12 Coenzyme-dependent D- -lysine mutase reaction.
    Biochemistry, 1972, Feb-15, Volume: 11, Issue:4

    Topics: Acetamides; Acetates; Alkylation; Borohydrides; Catalysis; Coenzymes; Enzyme Activation; Hydroxylamines; Imidazoles; Iodoacetates; Kinetics; Lysine; Magnesium; Methane; Nitro Compounds; Oxidation-Reduction; Oxidoreductases; Protein Binding; Pyridoxal Phosphate; Sulfhydryl Compounds; Tritium; Vitamin B 12

1972
Schiff bases of pyridoxal phosphate with active center lysines of ribonuclease A.
    Biochemistry, 1972, Jun-06, Volume: 11, Issue:12

    Topics: Acetates; Amino Acids; Binding Sites; Borohydrides; Chemical Phenomena; Chemistry; Chymotrypsin; Circular Dichroism; Cytosine Nucleotides; Hydrogen-Ion Concentration; Lysine; Optical Rotation; Oxidation-Reduction; Peptides; Phosphates; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Ribonucleases; Schiff Bases; Spectrophotometry; Trypsin; Ultraviolet Rays

1972
Selective modification of the mitochondrial isozyme of aspartate aminotransferase by -bromopropionate. I. Inactivation process and properties of inactivated enzyme.
    Biochemistry, 1972, Aug-15, Volume: 11, Issue:17

    Topics: Alkylation; Amino Acids; Animals; Aspartate Aminotransferases; Bromine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Circular Dichroism; Enzyme Activation; Kinetics; Lysine; Maleates; Mitochondria, Muscle; Myocardium; Propionates; Pyridoxal Phosphate; Spectrophotometry; Subcellular Fractions; Succinates; Sulfhydryl Compounds; Swine; Ultracentrifugation; Ultraviolet Rays

1972
Inactivation of bovine glutamate dehydrogenase by carbamyl phosphate and cyanate.
    The Journal of biological chemistry, 1972, Feb-10, Volume: 247, Issue:3

    Topics: Alanine; Aldehydes; Amino Acids; Animals; Carbamates; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cyanates; Glutamate Dehydrogenase; Kinetics; Lysine; Mathematics; Peptides; Phosphates; Picolines; Pyridoxal Phosphate; Trypsin

1972
Paradoxical inhibition of phosphorylase by pyridoxal phosphate. I. Studies on the reaction of pyridoxal phosphate with a specific lysine residue of phosphorylase b.
    The Journal of biological chemistry, 1972, Nov-10, Volume: 247, Issue:21

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apoproteins; Binding Sites; Borohydrides; Chemical Phenomena; Chemistry; Citrates; Enzyme Activation; Glucosephosphates; Glycogen; Imidazoles; Kinetics; Lysine; Macromolecular Substances; Muscles; Oxidation-Reduction; Phosphates; Phosphorylases; Pyridoxal Phosphate; Rabbits; Schiff Bases; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet

1972
Functional properties of ornithine-ketoacid aminotransferase from rat liver.
    Biochimica et biophysica acta, 1972, Nov-10, Volume: 289, Issue:1

    Topics: Animals; Apoproteins; Binding Sites; Buffers; Carbon Isotopes; Carboxylic Acids; Catalysis; Drug Stability; Glutamates; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Liver; Lysine; Ornithine; Phosphates; Pyridoxal Phosphate; Pyridoxamine; Pyrroles; Rats; Time Factors; Transaminases; Tromethamine

1972
Identification of lysines reactive with pyridoxal 5'-phosphate in glyceraldehyde-3-phosphate dehydrogenase.
    European journal of biochemistry, 1971, Jun-29, Volume: 20, Issue:4

    Topics: Amino Acid Sequence; Animals; Boron Compounds; Electrophoresis; Fluorescence; Glyceraldehyde-3-Phosphate Dehydrogenases; Lysine; Methylation; Muscles; Peptides; Pyridoxal Phosphate; Rabbits

1971
Rotational relaxation time of pyridoxyl 5-phosphate lysozyme.
    The Journal of biological chemistry, 1971, Sep-10, Volume: 246, Issue:17

    Topics: Acetates; Alkylation; Borohydrides; Cell Wall; Chemical Phenomena; Chemistry; Chemistry, Physical; Chromatography, Gel; Chromatography, Paper; Electrophoresis; Fluoresceins; Fluorescence; Fluorometry; Glucosamine; Hydrolysis; Iodides; Light; Lysine; Mathematics; Micrococcus; Muramidase; Oxidation-Reduction; Paper; Peptides; Picolines; Potassium; Pyridoxal Phosphate; Rotation; Sodium; Spectrophotometry; Thiocyanates; Trypsin; Viscosity

1971
Affinity labeling of pancreatic ribonuclease.
    The Journal of biological chemistry, 1971, Sep-10, Volume: 246, Issue:17

    Topics: Amino Acids; Animals; Binding Sites; Borohydrides; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Formates; Kinetics; Lysine; Oxidation-Reduction; Pancreas; Peptides; Phosphates; Pyridoxal Phosphate; Ribonucleases; Sodium; Spectrophotometry; Trypsin

1971
Nature of the binding site of pyridoxal 5'-phosphate to bovine serum albumin.
    Biochemistry, 1971, Jun-08, Volume: 10, Issue:12

    Topics: Alkanes; Amino Acid Sequence; Binding Sites; Carboxypeptidases; Chromatography, Ion Exchange; Fluorometry; Hydrogen-Ion Concentration; Lysine; Protein Binding; Pyridoxal Phosphate; Pyrrolidinones; Serum Albumin, Bovine; Spectrophotometry; Thiocyanates; Trypsin; Tyrosine; Urea

1971
Sequence of a segment of muscle glycogen phosphorylase containing the pyridoxal 5'-phosphate binding site.
    Biochemistry, 1971, Aug-03, Volume: 10, Issue:16

    Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Borohydrides; Carboxypeptidases; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cyanogen Bromide; Dansyl Compounds; Electrophoresis, Paper; Fluorometry; Glucosyltransferases; Kinetics; Leucyl Aminopeptidase; Lysine; Muscles; Oxidation-Reduction; Peptides; Phosphorylases; Protein Binding; Pyridoxal Phosphate; Rabbits; Rats; Sodium; Species Specificity; Spectrophotometry; Thermolysin; Trypsin; Ultraviolet Rays

1971
The phenylalanine-binding protein of Comamonas sp. (ATCC 11299a).
    The Journal of biological chemistry, 1971, Volume: 246, Issue:21

    Topics: Amino Acids; Anhydrides; Bacterial Proteins; Biological Transport; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Drug Stability; Electrophoresis, Disc; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Maleates; Molecular Weight; Nitrobenzenes; Phenylalanine; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Sodium Chloride; Ultracentrifugation; Urea

1971
Pyridoxal 5'-phosphate as a site-specific protein reagent for a catalytically critical lysine residue in rabbit muscle phosphoglucose isomerase.
    Biochemistry, 1971, Dec-21, Volume: 10, Issue:26

    Topics: Aldehydes; Animals; Binding Sites; Borohydrides; Chemical Phenomena; Chemistry; Electrophoresis, Paper; Fructosephosphates; Gluconates; Glucose-6-Phosphate Isomerase; Kinetics; Lysine; Muscles; Oxidation-Reduction; Peptides; Phosphoric Acids; Picolines; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Tritium; Ultracentrifugation; Ultraviolet Rays

1971
Effect of abnormal amino acid concentrations on blood-brain barrier.
    Experientia, 1971, Volume: 27, Issue:7

    Topics: Absorption; Amino Acids; Animals; Blood-Brain Barrier; Brain; Carbon Isotopes; Injections, Intraperitoneal; Lysine; Mice; Permeability; Pyridoxal Phosphate; Time Factors; Tissue Extracts; Tyrosine

1971
Purification and properties of an amine oxidase in bovine dental pulp.
    Experientia, 1971, Dec-15, Volume: 27, Issue:12

    Topics: Aminopropionitrile; Animals; Cattle; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Copper; Dental Pulp; Electrophoresis, Disc; Enzyme Activation; Isoniazid; Lysine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyridoxal Phosphate; Spectrophotometry; Vasopressins

1971
[Isolation and estimation of phosphopyridoxyllysine and pyridoxyllysine].
    Seikagaku. The Journal of Japanese Biochemical Society, 1971, Volume: 43, Issue:9

    Topics: Alanine; Amino Acids; Aminocaproates; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Lysine; Methionine; Proteins; Pyridoxal Phosphate; Pyridoxine; Valine

1971
Enzymatic and physiological properties of the yeast glutamate-alpha-ketoadipate transaminase.
    The Journal of biological chemistry, 1969, Oct-10, Volume: 244, Issue:19

    Topics: Adipates; Amino Acids; Aspartic Acid; Clone Cells; Culture Media; Enzyme Induction; Enzyme Repression; Feedback; Glutamates; Keto Acids; Kinetics; Lysine; Pyridoxal Phosphate; Saccharomyces; Stimulation, Chemical; Transaminases

1969
Regulation of glycogen metabolism in insect flight muscle. Purification and properties of phosphorylases in vitro and in vivo.
    The Journal of biological chemistry, 1970, Jun-10, Volume: 245, Issue:11

    Topics: Adenine Nucleotides; Amino Acids; Animals; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cystine; Diptera; Drug Stability; Electrophoresis, Disc; Glucosyltransferases; Glycogen; Kinetics; Lysine; Molecular Weight; Muscles; Physical Exertion; Pyridoxal Phosphate; Ultracentrifugation

1970
Lysine 2,3-aminomutase. Purification and properties of a pyridoxal phosphate and S-adenosylmethionine-activated enzyme.
    The Journal of biological chemistry, 1970, Apr-10, Volume: 245, Issue:7

    Topics: Acetone; Amino Acids; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Clostridium; Cysteine; Deuterium; Dialysis; Drug Stability; Electrophoresis; Electrophoresis, Disc; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxylamines; Intramolecular Transferases; Iron; Isomerases; Isoniazid; Kinetics; Lysine; Methionine; Methods; Molecular Weight; Nucleosides; Pyridoxal Phosphate; Pyridoxine; Streptomycin; Sulfhydryl Compounds; Temperature; Tritium

1970
Inactivation of tetrameric rabbit muscle pyruvate kinase by specific binding of 2 to 4 moles of pyridoxal 5'-phosphate.
    The Journal of biological chemistry, 1970, Jan-25, Volume: 245, Issue:2

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Amines; Animals; Binding Sites; Boron Compounds; Centrifugation, Density Gradient; Dialysis; Enzyme Activation; Hexosephosphates; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Lysine; Muscles; Osmolar Concentration; Oxidation-Reduction; Pyridines; Pyridoxal Phosphate; Pyruvate Kinase; Pyruvates; Rabbits; Spectrophotometry; Time Factors; Tromethamine; Ultraviolet Rays

1970
Bovine liver flutamate dehydrogenase. Sequence of a hexadecapeptide containing a lysyl residue reactive with pyridoxal 5'-phosphate.
    The Journal of biological chemistry, 1970, May-25, Volume: 245, Issue:10

    Topics: Alkylation; Amino Acid Sequence; Animals; Boron Compounds; Cattle; Chemical Phenomena; Chemistry; Fluorometry; Glutamate Dehydrogenase; Liver; Lysine; Oxidation-Reduction; Pyridoxal Phosphate; Sulfhydryl Compounds; Trypsin

1970
Studies on the fermentation of D-alpha-lysine. Purification and properties of an adenosine triphosphate regulated B 12-coenzyme-dependent D-alpha-lysine mutase complex from Clostridium sticklandii.
    Biochemistry, 1970, Dec-08, Volume: 9, Issue:25

    Topics: Adenosine Triphosphate; Alkylating Agents; Aminocaproates; Bacterial Proteins; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Clostridium; Electrophoresis, Disc; Hydrogen-Ion Concentration; Iodoacetates; Isomerases; Light; Lysine; Magnesium; Organophosphonates; Ornithine; Potassium; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Radiation Effects; Spectrophotometry; Stereoisomerism; Sulfhydryl Compounds; Temperature; Time Factors; Ultraviolet Rays; Vitamin B 12

1970
Pyridoxyl-5-phosphate-lysozyme. Physical studies.
    Biochimica et biophysica acta, 1970, Jul-27, Volume: 214, Issue:1

    Topics: Cell Wall; Chemical Phenomena; Chemistry; Electricity; Fluorescence; Fluorometry; Hydrogen-Ion Concentration; Light; Lysine; Micrococcus; Molecular Weight; Muramidase; Osmolar Concentration; Pyridoxal Phosphate

1970
The mode of binding of pyridoxal 5'-phosphate in glycogen phosphorylase.
    Biochemical and biophysical research communications, 1970, Nov-09, Volume: 41, Issue:3

    Topics: Amines; Animals; Binding Sites; Boron Compounds; Chemical Phenomena; Chemistry; Cysteamine; Fluorescence; Glucosyltransferases; Glycogen; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Models, Structural; Muscles; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Thiazoles

1970
Inhibition of elastin cross-linking by iproniazid and its counteraction by pyridoxal phosphate.
    Biochimica et biophysica acta, 1970, Nov-24, Volume: 222, Issue:2

    Topics: Adipates; Aldehydes; Amino Acids; Animals; Aorta; Carbon Isotopes; Chick Embryo; Culture Techniques; Elastin; Iproniazid; Isoniazid; Lysine; Pyridinium Compounds; Pyridoxal Phosphate

1970
Synthesis and properties of alpha and epsilon pyridoxyl lysines and their phosphorylated derivatives.
    Biochimie, 1971, Volume: 53, Issue:3

    Topics: Acetophenones; Amino Acids; Autoanalysis; Binding Sites; Buffers; Chemical Phenomena; Chemistry; Chloroquine; Chromatography, Paper; Chromatography, Thin Layer; Electrophoresis; Fluorescence; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Pyridoxal Phosphate; Solvents; Spectrophotometry

1971
Arginine racemase of Pseudomonas graveolens. I. Purification, crystallization, and properties.
    The Journal of biological chemistry, 1971, Aug-25, Volume: 246, Issue:16

    Topics: Alcohols; Amides; Aminobutyrates; Arginine; Boron Compounds; Catalysis; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Citrulline; Crystallization; Drug Stability; Ethionine; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Hydroxylamines; Isomerases; Kinetics; Light; Lysine; Molecular Weight; Ornithine; Oxidation-Reduction; Penicillamine; Phenylhydrazines; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Rotation; Spectrophotometry; Sulfates; Ultracentrifugation

1971
The effect of pyridoxal phosphate on rabbit muscle aldolase.
    Archives of biochemistry and biophysics, 1968, Volume: 128, Issue:2

    Topics: Acetone; Animals; Binding Sites; Boron Compounds; Chemical Phenomena; Chemistry; Chromatography, Gel; Crystallization; Cyanides; Fructose-Bisphosphate Aldolase; Lysine; Muscles; Peptides; Protein Hydrolysates; Pyridoxal Phosphate; Rabbits

1968
L-Lysine:alpha-ketoglutarate aminotransferase. II. Purification, crystallization, and properties.
    Biochemistry, 1968, Volume: 7, Issue:11

    Topics: Alcaligenes; Amino Acids; Chemical Precipitation; Chromatography, Ion Exchange; Crystallization; Drug Stability; Electrophoresis; Electrophoresis, Disc; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Lysine; Microscopy; Molecular Weight; Pyridoxal Phosphate; Spectrophotometry; Transaminases; Ultracentrifugation

1968
Schiff base formation by the lysyl and hydroxylysyl side chains of collagen.
    Biochemical and biophysical research communications, 1968, Dec-09, Volume: 33, Issue:5

    Topics: Animals; Binding Sites; Chromatography; Collagen; In Vitro Techniques; Lysine; Protein Denaturation; Pyridoxal Phosphate; Spectrophotometry

1968
Collagen has a discrete family of reactive hydroxylysyl and lysyl side-chain amino groups.
    Science (New York, N.Y.), 1969, Feb-07, Volume: 163, Issue:3867

    Topics: Amino Acid Sequence; Animals; Binding Sites; Collagen; Elastin; Hot Temperature; Lysine; Protein Denaturation; Pyridoxal Phosphate; Rats; Skin; Spectrophotometry

1969
Pyridoxal 5'-phosphate in alpha-glucan phosphorylase from the potato.
    Biochimica et biophysica acta, 1969, May-27, Volume: 178, Issue:3

    Topics: Acetophenones; Boron; Chemical Phenomena; Chemistry; Coloring Agents; Glucosyltransferases; Hydrogen-Ion Concentration; Lysine; Oxidation-Reduction; Plants; Protein Binding; Pyridoxal Phosphate; Quinones; Spectrophotometry; Tromethamine; Urea

1969
Crystalline amino acid racemase with low substrate specificity.
    Biochemical and biophysical research communications, 1969, May-08, Volume: 35, Issue:3

    Topics: Alanine; Amino Acids; Arginine; Butyrates; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Dialysis; Electrophoresis, Disc; Ethionine; Isomerases; Leucine; Lysine; Methionine; Methods; Molecular Weight; Pseudomonas; Pyridoxal Phosphate; Spectrophotometry; Ultracentrifugation

1969
Pyridoxal 5'-phosphate as a specific photosensitizer for histidine residue at the active site of 6-phosphogluconate dehydrogenase.
    Archives of biochemistry and biophysics, 1969, Volume: 133, Issue:1

    Topics: Amino Acids; Benzoates; Binding Sites; Candida; Histidine; Kinetics; Light; Lysine; Oxidation-Reduction; Phosphogluconate Dehydrogenase; Pyridoxal Phosphate; Radiation Effects

1969
Inhibition by pyridoxal-phosphate of glyceraldehyde-3-phosphate dehydrogenase.
    European journal of biochemistry, 1969, Volume: 8, Issue:3

    Topics: Animals; Chromatography, Ion Exchange; Chromatography, Paper; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Lysine; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Valine

1969
Isolation and identification of beta-lysine as an intermediate in lysine fermentation.
    The Journal of biological chemistry, 1966, Apr-10, Volume: 241, Issue:7

    Topics: Acetates; Ammonia; Butyrates; Chromatography, Paper; Clostridium; Coenzyme A; Fermentation; Glutathione; In Vitro Techniques; Ketoglutaric Acids; Lysine; Pyridoxal Phosphate

1966
Complexes of pyridoxal phosphate with amino acids, peptides, polylysine, and apotransaminase.
    Biochemical and biophysical research communications, 1967, Mar-09, Volume: 26, Issue:5

    Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Dipeptides; Glutamates; Glycine; Hydrogen-Ion Concentration; Lysine; Peptides; Pyridoxal Phosphate; Spectrophotometry; Transaminases

1967
[Spectrophotometric method of determining the content of amino groups in proteins using pyridoxal-5-phosphate].
    Laboratornoe delo, 1982, Issue:3

    Topics: Indicators and Reagents; Lysine; Proteins; Pyridoxal Phosphate; Spectrophotometry

1982
Pig liver phosphomevalonate kinase. 2. Participation of cysteinyl and lysyl groups in catalysis.
    Biochemistry, 1980, May-27, Volume: 19, Issue:11

    Topics: Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Kinetics; Liver; Lysine; Mevalonic Acid; Phosphotransferases; Phosphotransferases (Phosphate Group Acceptor); Pyridoxal Phosphate; Swine

1980
[Phenylalanyl-tRNA synthetase from E. coli MRE-600. Effect of chemical modification of lysine residues on the enzyme interaction with substrates].
    Biokhimiia (Moscow, Russia), 1981, Volume: 46, Issue:4

    Topics: Adenosine Triphosphate; Aldehydes; Amino Acyl-tRNA Synthetases; Diphosphates; Escherichia coli; Kinetics; Lysine; Magnesium; Phenylalanine-tRNA Ligase; Pyridoxal Phosphate

1981
Rabbit liver fructose 1,6-bisphosphatase: labeling of the active and allosteric sites with pyridoxal 5-phosphate and sequence of a nonapeptide from the active site.
    Archives of biochemistry and biophysics, 1981, Volume: 210, Issue:1

    Topics: Allosteric Site; Amino Acid Sequence; Animals; Binding Sites; Cyanogen Bromide; Fructose-Bisphosphatase; Liver; Lysine; Peptide Fragments; Pyridoxal Phosphate; Rabbits

1981
Modification of pyruvate, phosphate dikinase with pyridoxal 5'-phosphate: evidence for a catalytically critical lysine residue.
    Biochemistry, 1983, May-10, Volume: 22, Issue:10

    Topics: Bacteroides; Kinetics; Lysine; Phosphorus Radioisotopes; Phosphotransferases; Protein Binding; Pyridoxal Phosphate; Pyruvate, Orthophosphate Dikinase; Spectrophotometry, Ultraviolet

1983
Metabolism of glycerate-2,3-P2--VI. Lysyl-specific reagents inactivate the phosphoglycerate mutase, glycerate-2,3-P2 synthase and glycerate-2,3-P2 phosphatase activities of rabbit muscle phosphoglycerate mutase.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1984, Volume: 77, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry; Kinetics; Lysine; Muscles; Phosphoglycerate Mutase; Phosphoric Monoester Hydrolases; Phosphotransferases; Pyridoxal Phosphate; Rabbits; Trinitrobenzenesulfonic Acid

1984
Mechanism of thrombin binding to endothelial cells.
    Blood, 1983, Volume: 61, Issue:2

    Topics: Antithrombin III; Binding Sites; Endothelium; Heparin; Humans; Lysine; Pyridoxal Phosphate; Thrombin

1983
pH studies toward the elucidation of the auxiliary catalyst for pig heart aspartate aminotransferase.
    Biochemistry, 1983, Jan-18, Volume: 22, Issue:2

    Topics: Aspartate Aminotransferases; Aspartic Acid; Binding, Competitive; Dimethylformamide; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Lysine; Maleates; Myocardium; Pyridoxal Phosphate; Pyridoxamine; Temperature

1983
Pyridoxal phosphate as a probe in the active site of ribulose bisphosphate carboxylase/oxygenase.
    Archives of biochemistry and biophysics, 1983, Volume: 223, Issue:2

    Topics: Binding Sites; Carboxy-Lyases; Electrophoresis, Polyacrylamide Gel; Histidine; Lysine; Oxidation-Reduction; Photochemistry; Plants; Pyridoxal Phosphate; Pyridoxamine; Ribulose-Bisphosphate Carboxylase; Spectrum Analysis

1983
[Chemical modification of the lysine residues of bacterial formate dehydrogenase].
    Biokhimiia (Moscow, Russia), 1983, Volume: 48, Issue:5

    Topics: Alcaligenes; Aldehyde Oxidoreductases; Amino Acids; Binding Sites; Formaldehyde; Formate Dehydrogenases; Kinetics; Lysine; Protein Binding; Pyridoxal; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet

1983
Inactivation of yeast fatty acid synthetase by modifying the beta-ketoacyl reductase active lysine residue with pyridoxal 5'-phosphate.
    Archives of biochemistry and biophysics, 1983, Oct-01, Volume: 226, Issue:1

    Topics: Alcohol Oxidoreductases; Binding Sites; Electrophoresis, Polyacrylamide Gel; Fatty Acid Synthases; Kinetics; Lysine; Protein Binding; Pyridoxal Phosphate; Saccharomyces cerevisiae

1983
Role of lysine residues in the binding of glyceraldehyde-3-phosphate dehydrogenase to human erythrocyte membranes.
    Biochemical and biophysical research communications, 1983, Oct-31, Volume: 116, Issue:2

    Topics: Animals; Borohydrides; Erythrocyte Membrane; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Lysine; Pyridoxal Phosphate; Rabbits; Swine

1983
Pyridoxylation of essential lysines in the heparin-binding site of antithrombin III.
    The Journal of biological chemistry, 1984, Jan-25, Volume: 259, Issue:2

    Topics: Antithrombin III; Binding Sites; Chromatography, Affinity; Heparin; Humans; Lysine; Pyridoxal Phosphate; Spectrometry, Fluorescence

1984
Modification of a lysine residue of adrenodoxin reductase, essential for complex formation with adrenodoxin.
    Biochimica et biophysica acta, 1984, Apr-27, Volume: 786, Issue:1-2

    Topics: Adrenal Cortex; Adrenodoxin; Animals; Binding Sites; Cattle; Circular Dichroism; Ferredoxin-NADP Reductase; Lysine; NADH Dehydrogenase; NADH, NADPH Oxidoreductases; NADP; Neuraminidase; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship

1984
Purification and properties of ornithine aminotransferase from rat brain.
    Experientia, 1984, Apr-15, Volume: 40, Issue:4

    Topics: Amino Acids, Branched-Chain; Animals; Brain; Ketoglutaric Acids; Kidney; Kinetics; Liver; Lysine; Male; Ornithine-Oxo-Acid Transaminase; Pyridoxal Phosphate; Rats; Substrate Specificity; Transaminases

1984
Phosphate as a probe of structure and function of aspartate transaminase isozymes.
    Progress in clinical and biological research, 1984, Volume: 144B

    Topics: Affinity Labels; Animals; Aspartate Aminotransferases; Binding Sites; Cytosol; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Mitochondria; Phosphates; Protein Binding; Pyridoxal Phosphate; Thermodynamics

1984
Site-specific modification of Escherichia coli DNA polymerase I large fragment with pyridoxal 5'-phosphate.
    Biochemistry, 1984, Apr-24, Volume: 23, Issue:9

    Topics: Binding Sites; Deoxyribonucleotides; DNA Polymerase I; Escherichia coli; Lysine; Pyridoxal Phosphate

1984
Modification of hydroxymethylbilane synthase (porphobilinogen deaminase) by pyridoxal 5'-phosphate. Demonstration of an essential lysine residue.
    The Biochemical journal, 1984, Aug-15, Volume: 222, Issue:1

    Topics: Ammonia-Lyases; Animals; Binding Sites; Borohydrides; Euglena gracilis; Hydrogen-Ion Concentration; Hydroxymethylbilane Synthase; Kinetics; Lysine; Oxidation-Reduction; Pyridoxal Phosphate; Rhodobacter sphaeroides; Uroporphyrinogen III Synthetase

1984
Evidence for essential lysines in heparin cofactor II.
    Biochemical and biophysical research communications, 1984, Nov-14, Volume: 124, Issue:3

    Topics: Chromatography, Affinity; Glycoproteins; Heparin Cofactor II; Humans; Lysine; Pyridoxal Phosphate; Sepharose; Spectrophotometry; Thrombin

1984
Pyridoxylation of essential lysine residues of mitochondrial adenosine triphosphatase.
    Biochimica et biophysica acta, 1982, Feb-17, Volume: 679, Issue:2

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Bicarbonates; Binding Sites; Cattle; Kinetics; Lysine; Macromolecular Substances; Magnesium; Mitochondria, Heart; Proton-Translocating ATPases; Pyridoxal Phosphate

1982
Effects of epsilon-pyridoxyllysine bound to dietary protein on the vitamin B-6 status of rats.
    The Journal of nutrition, 1980, Volume: 110, Issue:5

    Topics: Animals; Aspartate Aminotransferases; Biological Assay; Body Weight; Dietary Proteins; Dose-Response Relationship, Drug; Erythrocytes; Liver; Lysine; Male; Protein Binding; Pyridoxal; Pyridoxal Phosphate; Pyridoxine; Rats; Serum Albumin, Bovine

1980
Fluorescence of cowpea-chlorotic-mottle virus modified with pyridoxal 5'-phosphate.
    European journal of biochemistry, 1980, Volume: 105, Issue:2

    Topics: Energy Transfer; Fluorescence; Lysine; Nucleoproteins; Plant Viruses; Protein Conformation; Pyridoxal Phosphate; Viral Proteins

1980
L-Lysine: 2-oxoglutarate 6-aminotransferase. Subunit structure composed of non-identical polypeptides and pyridoxal 5'-phosphate-binding subunit.
    Journal of biochemistry, 1980, Volume: 87, Issue:5

    Topics: Amino Acids; Binding Sites; Flavobacterium; L-Lysine 6-Transaminase; Lysine; Macromolecular Substances; Molecular Weight; Protein Binding; Pyridoxal Phosphate; Transaminases

1980
The reaction of pyridoxal 5'-phosphate with an essential lysine residue of saccharopine dehydrogenase (L-lysine-forming).
    The Journal of biological chemistry, 1980, Aug-10, Volume: 255, Issue:15

    Topics: Binding Sites; Hydrogen-Ion Concentration; Kinetics; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Pyridoxal Phosphate; Saccharopine Dehydrogenases; Spectrophotometry

1980
Chemical modification of an essential lysine at the active site of enoyl-CoA reductase in fatty acid synthetase.
    Archives of biochemistry and biophysics, 1980, Apr-15, Volume: 201, Issue:1

    Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Fatty Acid Desaturases; Fatty Acid Synthases; Geese; Lysine; Pyridoxal Phosphate

1980
Selective chemical modification of the active sites of the ketoacyl reductase and enoyl reductase of fatty acid synthetase from lactating rat mammary glands.
    The International journal of biochemistry, 1980, Volume: 12, Issue:4

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Acyl Carrier Protein; Alcohol Oxidoreductases; Animals; Arginine; Binding Sites; Enoyl-(Acyl-Carrier Protein) Reductase (NADPH, B-Specific); Fatty Acid Synthases; Female; Lactation; Lysine; Mammary Glands, Animal; NADP; Oxidoreductases; Phenylglyoxal; Pregnancy; Pyridoxal Phosphate; Rats

1980
Chemical modification of critical catalytic residues of lysine, arginine, and tryptophan in human glucose phosphate isomerase.
    The Journal of biological chemistry, 1981, Jan-25, Volume: 256, Issue:2

    Topics: Affinity Labels; Arginine; Bromosuccinimide; Circular Dichroism; Cyclohexanones; Diacetyl; Female; Glucose-6-Phosphate Isomerase; Humans; Kinetics; Lysine; Molecular Weight; Placenta; Pregnancy; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Tryptophan

1981
Laser photo-CIDNP NMR of pyridoxal phosphate and pyridoxyllysine residues: an extrinsic probe for non-aromatic amino acid residues in proteins.
    Biochemical and biophysical research communications, 1980, Nov-17, Volume: 97, Issue:1

    Topics: Amino Acids; Animals; Cattle; Lasers; Lysine; Magnetic Resonance Spectroscopy; Pancreas; Proteins; Pyridoxal; Pyridoxal Phosphate; Ribonucleases

1980
Phenol hydroxylase from yeast: a lysyl residue essential for binding of reduced nicotinamide adenine dinucleotide phosphate.
    Biochemistry, 1980, Oct-28, Volume: 19, Issue:22

    Topics: Amino Acids; Lysine; Mixed Function Oxygenases; NADP; Phenols; Pyridoxal Phosphate; Saccharomyces cerevisiae; Spectrophotometry

1980
Structure-function relations in platelet-thrombin reactions. Inhibition of platelet-thrombin interactions by lysine modification.
    The Journal of biological chemistry, 1981, Feb-25, Volume: 256, Issue:4

    Topics: Blood Platelets; Heparin; Humans; Kinetics; Lysine; Platelet Aggregation; Pyridoxal Phosphate; Thrombin

1981
Modification of mouse testicular lactate dehydrogenase by pyridoxal 5'-phosphate.
    The Biochemical journal, 1980, Nov-01, Volume: 191, Issue:2

    Topics: Animals; Binding Sites; Coenzymes; Cysteine; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lysine; Male; Mice; Nucleotides; Pyridoxal Phosphate; Testis

1980
Evidence for an essential lysine at the active site of L-histidinol:NAD+ oxidoreductase; a bifunctional dehydrogenase.
    European journal of biochemistry, 1981, Volume: 118, Issue:1

    Topics: Alcohol Oxidoreductases; Binding Sites; Formaldehyde; Histidinol; Kinetics; Lysine; Protein Binding; Pyridoxal Phosphate; Salmonella typhimurium; Spectrophotometry, Ultraviolet

1981
Chemical modification of coenzyme B12-dependent diol dehydrase with pyridoxal 5'-phosphate: lysyl residue essential for interaction between two components of the enzyme.
    Archives of biochemistry and biophysics, 1981, Oct-15, Volume: 211, Issue:2

    Topics: Apoenzymes; Chemical Phenomena; Chemistry; Cobamides; Hydro-Lyases; Kinetics; Klebsiella pneumoniae; Lysine; Oxidation-Reduction; Propanediol Dehydratase; Propylene Glycol; Propylene Glycols; Pyridoxal Phosphate; Spectrum Analysis; Vitamin B 12

1981
Identification of the apparently essential lysine residues in phospholipase C (Bacillus cereus).
    The Biochemical journal, 1981, Mar-01, Volume: 193, Issue:3

    Topics: Amino Acids; Bacillus cereus; Binding Sites; Chromatography, Gel; Chymotrypsin; Lysine; Peptide Fragments; Phospholipases; Pyridoxal Phosphate; Type C Phospholipases

1981
Stereochemistry of meso-alpha,epsilon-diaminopimelate decarboxylase reaction: the first evidence for pyridoxal 5'-phosphate dependent decarboxylation with inversion of configuration.
    Biochemistry, 1981, Nov-24, Volume: 20, Issue:24

    Topics: Bacillus; Bacterial Proteins; Cadaverine; Carboxy-Lyases; Deuterium; Kinetics; Lysine; Piperidines; Pyridoxal Phosphate; Radioisotope Dilution Technique

1981
Human erythrocytes glucose-6-phosphate dehydrogenase: labelling of a reactive lysyl residue by pyridoxal-5'-phosphate.
    Biochemical and biophysical research communications, 1981, Dec-31, Volume: 103, Issue:4

    Topics: Binding Sites; Erythrocytes; Glucosephosphate Dehydrogenase; Humans; Kinetics; Lysine; Protein Binding; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet

1981
Structural similarities in the active-site region between potato and rabbit muscle phosphorylases: a lysyl residue located close to the pyridoxal 5'-phosphate.
    Journal of biochemistry, 1982, Volume: 91, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding Sites; Lysine; Muscles; Phosphorylases; Plants; Pyridoxal Phosphate; Rabbits; Species Specificity

1982
The reactions of pyridoxal 5'-phosphate with the M4 and H4 isoenzymes of pig lactate dehydrogenase.
    Archives of biochemistry and biophysics, 1982, Volume: 215, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Isoenzymes; L-Lactate Dehydrogenase; Lysine; Myocardium; NAD; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Spectrophotometry; Sulfhydryl Compounds; Swine

1982
4-Aminobutyrate aminotransferase, reaction of P'P2-bis(5'-pyridoxal) diphosphate with lysyl residues connected with catalytic activity.
    The Journal of biological chemistry, 1982, Sep-25, Volume: 257, Issue:18

    Topics: 4-Aminobutyrate Transaminase; Animals; Apoenzymes; Binding Sites; Brain; Kinetics; Lysine; Protein Binding; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine; Transaminases

1982
The involvement of a lysine residue at the active site of the enoyl reductase of pigeon liver fatty acid synthetase.
    Biochemical and biophysical research communications, 1982, Aug-31, Volume: 107, Issue:4

    Topics: Animals; Binding Sites; Columbidae; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acid Synthases; Kinetics; Liver; Lysine; Oxidoreductases; Protein Binding; Pyridoxal Phosphate; Spectrophotometry

1982
Structure-function relationships in Escherichia coli translational elongation factor G: modification of lysine residues by the site-specific reagent pyridoxal phosphate.
    Biochemistry, 1982, Oct-12, Volume: 21, Issue:21

    Topics: Escherichia coli; Lysine; Mathematics; Peptide Elongation Factor G; Peptide Elongation Factors; Protein Biosynthesis; Pyridoxal Phosphate; Structure-Activity Relationship; Time Factors; Trypsin

1982
Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides. Isolation and sequence of a peptide containing an essential lysine.
    Biochemistry, 1982, Dec-07, Volume: 21, Issue:25

    Topics: Amino Acid Sequence; Borohydrides; Glucosephosphate Dehydrogenase; Leuconostoc; Lysine; Macromolecular Substances; Peptide Fragments; Pyridoxal Phosphate; Trypsin

1982
Topology of CNS myelin proteolipid protein: evidence for the nonenzymatic glycosylation of extracytoplasmic domains in normal and diabetic animals.
    Biochemistry, 1994, Aug-30, Volume: 33, Issue:34

    Topics: Amino Acid Sequence; Animals; Binding Sites; Borohydrides; Brain; Cattle; Cytoplasm; Diabetes Mellitus, Experimental; Glycosylation; In Vitro Techniques; Lysine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Models, Molecular; Molecular Sequence Data; Molecular Structure; Myelin Proteins; Myelin Proteolipid Protein; Oxidation-Reduction; Pyridoxal Phosphate

1994
Inactivation of Leuconostoc mesenteroids NRRL B-512F dextransucrase by specific modification of lysine residues with pyridoxal-5'-phosphate.
    Journal of enzyme inhibition, 1995, Volume: 8, Issue:4

    Topics: Binding Sites; Borohydrides; Catalysis; Dose-Response Relationship, Drug; Glucosyltransferases; Leuconostoc; Lysine; Pyridoxal Phosphate; Spectrometry, Fluorescence; Time Factors

1995
Acid-base chemical mechanism of O-acetylserine sulfhydrylases-A and -B from pH studies.
    Biochemistry, 1995, Sep-26, Volume: 34, Issue:38

    Topics: Acetates; Binding Sites; Catalysis; Cysteine Synthase; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lysine; Models, Chemical; Nitrobenzoates; Pyridoxal Phosphate; Salmonella typhimurium; Schiff Bases; Serine; Spectrophotometry; Sulfhydryl Compounds; Thermodynamics; Titrimetry

1995
Examining the structural and chemical flexibility of the active site base, Lys-258, of Escherichia coli aspartate aminotransferase by replacement with unnatural amino acids.
    Biochemistry, 1995, Sep-26, Volume: 34, Issue:38

    Topics: Aspartate Aminotransferases; Binding Sites; Cysteine; Escherichia coli; Imines; Lysine; Models, Chemical; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Pyridoxamine; Spectrophotometry; Structure-Activity Relationship; Titrimetry

1995
Topological disposition of lysine 943 in native Na+/K(+)-transporting ATPase.
    Biochemistry, 1995, Jul-25, Volume: 34, Issue:29

    Topics: Amino Acid Sequence; Animals; Borohydrides; Cell Membrane; Chromatography, High Pressure Liquid; Chymotrypsin; Immunosorbent Techniques; Indicators and Reagents; Isoleucine; Kidney Medulla; Lipid Bilayers; Lysine; Macromolecular Substances; Membrane Lipids; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Pyridoxal Phosphate; Saponins; Sheep; Sodium-Potassium-Exchanging ATPase; Trypsin

1995
Identification of a lysine residue in the NADH-binding site of salicylate hydroxylase from Pseudomonas putida S-1.
    Journal of biochemistry, 1995, Volume: 117, Issue:3

    Topics: Amino Acid Sequence; Binding Sites; Chymotrypsin; Lysine; Mixed Function Oxygenases; Molecular Sequence Data; NAD; Pseudomonas putida; Pyridoxal Phosphate; Trinitrobenzenesulfonic Acid

1995
Pulsed electron paramagnetic resonance studies of the lysine 2,3-aminomutase substrate radical: evidence for participation of pyridoxal 5'-phosphate in a radical rearrangement.
    Biochemistry, 1995, Aug-08, Volume: 34, Issue:31

    Topics: Amino Acid Isomerases; Anions; Chlorides; Clostridium; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Intramolecular Transferases; Lysine; Models, Chemical; Pyridoxal Phosphate; Sulfates

1995
Role of lysine residues in the nucleotides binding to bovine liver high-Km aldehyde reductase.
    The international journal of biochemistry & cell biology, 1995, Volume: 27, Issue:5

    Topics: Aldehyde Reductase; Amino Acid Sequence; Animals; Cattle; Hot Temperature; Liver; Lysine; Molecular Sequence Data; NADP; Nucleotides; Protein Binding; Pyridines; Pyridoxal Phosphate; Trinitrobenzenesulfonic Acid

1995
Aminolevulinate synthase: lysine 313 is not essential for binding the pyridoxal phosphate cofactor but is essential for catalysis.
    Protein science : a publication of the Protein Society, 1995, Volume: 4, Issue:5

    Topics: 5-Aminolevulinate Synthetase; Amino Acid Sequence; Base Sequence; Catalysis; Circular Dichroism; Glycine; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry

1995
Essential lysine residue in glutathione reductase: chemical modification by pyridoxal 5'-phosphate.
    Biochemistry and molecular biology international, 1995, Volume: 36, Issue:2

    Topics: Adenosine Monophosphate; Binding Sites; Borohydrides; Glutathione; Glutathione Reductase; Lysine; NAD; NADP; Pyridoxal Phosphate; Schiff Bases; Spectrometry, Fluorescence; Yeasts

1995
Local structural difference between human and bovine band 3 in the anion transport inhibitor-binding region.
    The international journal of biochemistry & cell biology, 1995, Volume: 27, Issue:6

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anion Exchange Protein 1, Erythrocyte; Cattle; Cell Membrane Permeability; Chromatography; Chymotrypsin; Circular Dichroism; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Humans; Lysine; Peptide Fragments; Pyridoxal Phosphate; Serine Endopeptidases

1995
Biochemical analysis of human immunodeficiency virus-1 reverse transcriptase containing a mutation at position lysine 263.
    The Journal of biological chemistry, 1993, Feb-05, Volume: 268, Issue:4

    Topics: Base Sequence; Cloning, Molecular; HIV Reverse Transcriptase; HIV-1; In Vitro Techniques; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Pyridoxal Phosphate; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribonuclease H; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Substrate Specificity

1993
Identification of essential lysyl and cysteinyl residues, and the amino acid sequence at the substrate-binding site of retinal oxidase.
    Biochimica et biophysica acta, 1995, Apr-13, Volume: 1243, Issue:3

    Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Borohydrides; Chloromercuribenzoates; Cyanogen Bromide; Cysteine; Cytosol; Liver; Lysine; Male; Molecular Sequence Data; p-Chloromercuribenzoic Acid; Pyridoxal Phosphate; Rabbits; Retinal Dehydrogenase; Sequence Analysis; Trypsin

1995
Acidic residues important for substrate binding and cofactor reactivity in eukaryotic ornithine decarboxylase identified by alanine scanning mutagenesis.
    The Journal of biological chemistry, 1995, May-19, Volume: 270, Issue:20

    Topics: Animals; Arginine; Base Sequence; Binding Sites; Eukaryotic Cells; Kinetics; Leishmania donovani; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Ornithine; Ornithine Decarboxylase; Protozoan Proteins; Pyridoxal Phosphate; Recombinant Fusion Proteins; Species Specificity; Substrate Specificity; Trypanosoma brucei brucei

1995
An essential lysyl residue (Lys208) in the substrate-binding site of porcine FAD-containing monooxygenase.
    European journal of biochemistry, 1995, May-01, Volume: 229, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Female; Lysine; Microsomes, Liver; Molecular Sequence Data; NADP; Oxygenases; Peptide Fragments; Peptide Mapping; Pyridoxal Phosphate; Substrate Specificity; Swine

1995
Human glucose-6-phosphate dehydrogenase. Lysine 205 is dispensable for substrate binding but essential for catalysis.
    FEBS letters, 1995, Jun-05, Volume: 366, Issue:1

    Topics: Base Sequence; Binding Sites; Catalysis; Cloning, Molecular; DNA, Complementary; Escherichia coli; Glucosephosphate Dehydrogenase; Humans; Hydrogen Bonding; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Substrate Specificity

1995
Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue.
    Biochemistry, 1995, Jan-17, Volume: 34, Issue:2

    Topics: Animals; Aspartate Aminotransferases; Binding Sites; Catalysis; Chickens; Crystallography, X-Ray; Escherichia coli; Histidine; Ketoglutaric Acids; Lysine; Protein Binding; Pyridoxal Phosphate; Pyridoxamine; Structure-Activity Relationship; Substrate Specificity

1995
Identification of reactive lysines in phosphoenolpyruvate carboxykinases from Escherichia coli and Saccharomyces cerevisiae.
    FEBS letters, 1995, Feb-27, Volume: 360, Issue:2

    Topics: Amino Acid Sequence; Binding Sites; Escherichia coli; Lysine; Molecular Sequence Data; Peptides; Phosphoenolpyruvate Carboxykinase (GTP); Pyridoxal Phosphate; Saccharomyces cerevisiae; Sequence Alignment; Sequence Homology, Amino Acid

1995
NMR studies of 1H resonances in the 10-18-ppm range for cytosolic aspartate aminotransferase.
    The Journal of biological chemistry, 1994, Nov-11, Volume: 269, Issue:45

    Topics: Amino Acid Sequence; Animals; Aspartate Aminotransferases; Base Sequence; Cloning, Molecular; Cytosol; DNA Primers; Glutamine; Histidine; Hydrogen; Hydrogen Bonding; Lysine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Sensitivity and Specificity; Swine

1994
Evidences for physically different catalytic and regulatory nucleotide binding sites on the chloroplast H(+)-ATPase.
    Biological chemistry Hoppe-Seyler, 1994, Volume: 375, Issue:1

    Topics: Adenosine Diphosphate; Binding Sites; Catalysis; Chloroplasts; Hydrolysis; Light; Lysine; Molecular Weight; Nucleotides; Proton-Translocating ATPases; Pyridoxal Phosphate; Tyrosine

1994
Pyridoxal 5'-phosphate probes at Lys-480 can sense the binding of ATP and the formation of phosphoenzymes in Na+,K(+)-ATPase.
    The Journal of biological chemistry, 1994, Mar-11, Volume: 269, Issue:10

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Kidney; Lysine; Molecular Probes; Molecular Sequence Data; Organophosphates; Protein Conformation; Pyridoxal Phosphate; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence; Swine

1994
Reactivity of cysteinyl, arginyl, and lysyl residues of Escherichia coli phosphoenolpyruvate carboxykinase against group-specific chemical reagents.
    Journal of protein chemistry, 1993, Volume: 12, Issue:5

    Topics: Arginine; Binding Sites; Cysteine; Diacetyl; Escherichia coli; Glyoxal; Kinetics; Lysine; Phosphoenolpyruvate Carboxykinase (GTP); Pyrenes; Pyridoxal Phosphate; Sulfhydryl Reagents

1993
Extracytoplasmic disposition of lysine beta 165 of acetylcholine receptor.
    Biochemistry, 1994, May-03, Volume: 33, Issue:17

    Topics: Amino Acid Sequence; Animals; Borohydrides; Cell Membrane; Electric Organ; Lysine; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Pyridoxal Phosphate; Receptors, Cholinergic; Saponins; Thermolysin; Torpedo; Trypsin

1994
Replacement of active-site lysine-239 of thermostable aspartate aminotransferase by S-(2-aminoethyl)cysteine: properties of the mutant enzyme.
    Journal of biochemistry, 1994, Volume: 115, Issue:1

    Topics: Aspartate Aminotransferases; Binding Sites; Cysteine; Enzyme Stability; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Pyridoxal Phosphate; Temperature; Thermodynamics

1994
Studies of the active-site lysyl residue of thermostable aspartate aminotransferase: combination of site-directed mutagenesis and chemical modification.
    Journal of biochemistry, 1994, Volume: 115, Issue:1

    Topics: Aspartate Aminotransferases; Bacillus; Binding Sites; Circular Dichroism; Cysteine; Enzyme Stability; Lysine; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Structure-Activity Relationship; Temperature

1994
Heme biosynthesis in mammalian systems: evidence of a Schiff base linkage between the pyridoxal 5'-phosphate cofactor and a lysine residue in 5-aminolevulinate synthase.
    Protein science : a publication of the Protein Society, 1993, Volume: 2, Issue:11

    Topics: 5-Aminolevulinate Synthetase; Amino Acid Sequence; Animals; Base Sequence; Boranes; Erythrocytes; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Mapping; Pyridoxal; Pyridoxal Phosphate; Recombinant Proteins; Schiff Bases; Sequence Homology, Amino Acid; Trypsin

1993
Determination of a functional lysine residue of a plant cysteine synthase by site-directed mutagenesis, and the molecular evolutionary implications.
    FEBS letters, 1993, Aug-09, Volume: 328, Issue:1-2

    Topics: Amino Acid Sequence; Base Sequence; Biological Evolution; Cysteine Synthase; Escherichia coli; Gene Expression Regulation, Enzymologic; Glycine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Plants; Plasmids; Pyridoxal Phosphate; Structure-Activity Relationship

1993
Chemical modification of bacteriophage T4 deoxynucleotide kinase. Evidence of a single catalytic region.
    The Journal of biological chemistry, 1993, Jan-25, Volume: 268, Issue:3

    Topics: Amino Acid Sequence; Bacteriophage T4; Binding Sites; Chromatography, High Pressure Liquid; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Kinetics; Lysine; Molecular Sequence Data; Nucleoside-Phosphate Kinase; Phosphorylation; Pyridoxal Phosphate; Substrate Specificity; Thymidine Monophosphate

1993
Selective modification of Sendai virus hemagglutinin neuraminidase by pyridoxal 5'-phosphate: evidence for an allosteric modulation of neuraminidase activity.
    Biochimica et biophysica acta, 1993, Feb-13, Volume: 1161, Issue:2-3

    Topics: Allosteric Regulation; Amino Acids; Chromatography, High Pressure Liquid; Hemagglutination, Viral; HN Protein; Humans; Lysine; Parainfluenza Virus 1, Human; Pyridoxal Phosphate; Substrate Specificity

1993
The identification of a lysine residue reactive to pyridoxal-5-phosphate in the glycerol dehydrogenase from the thermophile Bacillus stearothermophilus.
    Biochimica et biophysica acta, 1993, Oct-06, Volume: 1202, Issue:2

    Topics: Amino Acid Sequence; Dose-Response Relationship, Drug; Enzyme Activation; Geobacillus stearothermophilus; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Fragments; Pyridoxal Phosphate; Sugar Alcohol Dehydrogenases; Trypsin

1993
Molecular cloning, nucleotide sequencing, and affinity labeling of bovine liver UDP-glucose pyrophosphorylase.
    Journal of biochemistry, 1993, Volume: 114, Issue:1

    Topics: Affinity Labels; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Cloning, Molecular; Dictyostelium; Liver; Lysine; Molecular Sequence Data; Oligonucleotide Probes; Pyridoxal Phosphate; Restriction Mapping; Sequence Homology, Amino Acid; Solanum tuberosum; Uridine Triphosphate; UTP-Glucose-1-Phosphate Uridylyltransferase

1993
Labeling of lysine 492 with pyridoxal 5'-phosphate in the sarcoplasmic reticulum Ca(2+)-ATPase. Lysine 492 residue is located outside the fluorescein 5-isothiocyanate-binding region in or near the ATP binding site.
    The Journal of biological chemistry, 1993, Oct-05, Volume: 268, Issue:28

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Calcium-Transporting ATPases; Chromatography, High Pressure Liquid; Fluorescein-5-isothiocyanate; Hydrolysis; Lysine; Molecular Sequence Data; Organophosphates; Peptide Mapping; Pyridoxal Phosphate; Rabbits; Sarcoplasmic Reticulum

1993
Mutant aspartate aminotransferase (K258H) without pyridoxal-5'-phosphate-binding lysine residue. Structural and catalytic properties.
    European journal of biochemistry, 1993, Feb-01, Volume: 211, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Binding Sites; Catalysis; Chickens; Circular Dichroism; Crystallization; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Mitochondria; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Protein Folding; Pyridoxal Phosphate; Spectrophotometry; X-Ray Diffraction

1993
Lysine 87 in the beta subunit of tryptophan synthase that forms an internal aldimine with pyridoxal phosphate serves critical roles in transimination, catalysis, and product release.
    The Journal of biological chemistry, 1993, Apr-25, Volume: 268, Issue:12

    Topics: Catalysis; Circular Dichroism; Imines; Isomerism; Lysine; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Salmonella typhimurium; Spectrum Analysis; Tryptophan Synthase

1993
Intersubunit location of the active site of mammalian ornithine decarboxylase as determined by hybridization of site-directed mutants.
    Biochemistry, 1993, Jun-08, Volume: 32, Issue:22

    Topics: Alanine; Animals; Base Sequence; Binding Sites; Cysteine; Eflornithine; Lysine; Macromolecular Substances; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Ornithine Decarboxylase; Pyridoxal Phosphate; Structure-Activity Relationship

1993
Evidence of an essential lysine in pig liver 5-aminolevulinic acid dehydratase.
    The international journal of biochemistry & cell biology, 1995, Volume: 27, Issue:12

    Topics: Animals; Enzyme Inhibitors; Kinetics; Levulinic Acids; Liver; Lysine; Models, Molecular; Porphobilinogen; Porphobilinogen Synthase; Pyridoxal Phosphate; Pyridoxamine; Pyruvates; Pyruvic Acid; Swine

1995
An antagonist-insensitive P2X receptor expressed in epithelia and brain.
    The EMBO journal, 1996, Jan-02, Volume: 15, Issue:1

    Topics: Adenosine Triphosphate; Animals; Base Sequence; Brain; Cloning, Molecular; DNA, Complementary; Epithelium; Gene Expression; Lysine; Molecular Sequence Data; Oligonucleotides; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; RNA, Messenger; Salivary Glands; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Structure-Activity Relationship; Suramin

1996
Site-directed mutagenesis of lysine382, the activator-binding site, of ADP-glucose pyrophosphorylase from Anabaena PCC 7120.
    Biochemistry, 1996, Mar-05, Volume: 35, Issue:9

    Topics: Allosteric Regulation; Amino Acid Sequence; Anabaena; Base Sequence; Binding Sites; Cloning, Molecular; Enzyme Activation; Enzyme Inhibitors; Enzyme Stability; Escherichia coli; Glucose-1-Phosphate Adenylyltransferase; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotidyltransferases; Oligodeoxyribonucleotides; Point Mutation; Pyridoxal Phosphate; Recombinant Proteins

1996
Energizing effects of illumination on the reactivities of lysine residues of the gamma subunit of chloroplast ATP synthase.
    European journal of biochemistry, 1996, Mar-01, Volume: 236, Issue:2

    Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Cattle; Chloroplasts; Hydrogen-Ion Concentration; Lysine; Membrane Potentials; Molecular Sequence Data; Photochemistry; Photosynthesis; Proton-Translocating ATPases; Pyridoxal Phosphate; Sequence Alignment; Sequence Homology, Amino Acid; Spinacia oleracea

1996
Evidence for an essential lysyl residue in phospholipase D from Streptomyces sp. by modification with diethyl pyrocarbonate and pyridoxal 5-phosphate.
    Biochemistry, 1996, Jul-30, Volume: 35, Issue:30

    Topics: Binding Sites; Circular Dichroism; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Phospholipase D; Protein Conformation; Pyridoxal Phosphate; Streptomyces; Sulfhydryl Compounds

1996
An essential lysine in the substrate-binding site of ornithine carbamoyltransferase.
    European journal of biochemistry, 1996, Jul-15, Volume: 239, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding Sites; Borohydrides; Carbamyl Phosphate; Dolphins; Enzyme Inhibitors; Escherichia coli; Humans; Kinetics; Liver; Lysine; Molecular Sequence Data; Ornithine Carbamoyltransferase; Peptide Fragments; Peptide Mapping; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Trypsin

1996
Characterization of pyridoxal phosphate as an optical label for measuring electrostatic potentials in proteins.
    Journal of photochemistry and photobiology. B, Biology, 1996, Volume: 32, Issue:1-2

    Topics: Acrylamide; Acrylamides; Affinity Labels; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Potentiometry; Protein Binding; Protein Conformation; Proteins; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry

1996
Pyridoxal 5'-phosphate binds to a lysine residue in the adenosine 3'-phosphate 5'-phosphosulfate recognition site of glycolipid sulfotransferase from human renal cancer cells.
    Glycoconjugate journal, 1995, Volume: 12, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Carbohydrate Sequence; Humans; Kidney Neoplasms; Lysine; Molecular Sequence Data; Phosphoadenosine Phosphosulfate; Pyridoxal Phosphate; Sulfotransferases; Tumor Cells, Cultured

1995
Pyridoxal 5'-phosphate binding of a recombinant rat serine: pyruvate/alanine:glyoxylate aminotransferase.
    Journal of biochemistry, 1996, Volume: 119, Issue:5

    Topics: Alanine Transaminase; Amino Acid Sequence; Animals; Apoenzymes; Aspartate Aminotransferases; D-Alanine Transaminase; Escherichia coli; Geobacillus stearothermophilus; Kinetics; Lysine; Molecular Sequence Data; Protein Binding; Pyridoxal Phosphate; Rats; Recombinant Proteins; Schiff Bases; Spectrophotometry, Ultraviolet; Swine; Transaminases

1996
Reactivity of essential cysteine and lysine residues present at the catalytic domain of pig heart mitochondrial malate dehydrogenase.
    Journal of enzyme inhibition, 1995, Volume: 9, Issue:3

    Topics: Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Lysine; Malate Dehydrogenase; Mitochondria, Heart; NAD; o-Phthalaldehyde; Pyridoxal Phosphate; Swine

1995
A change in the internal aldimine lysine (K42) in O-acetylserine sulfhydrylase to alanine indicates its importance in transimination and as a general base catalyst.
    Biochemistry, 1996, Oct-15, Volume: 35, Issue:41

    Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; Cysteine Synthase; DNA Primers; Escherichia coli; Imines; Kinetics; Lysine; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Schiff Bases; Spectrophotometry

1996
Chemical modification of notexin from Notechis scutatus scutatus (Australian tiger snake) venom with pyridoxal-5'-phosphate.
    Journal of protein chemistry, 1996, Volume: 15, Issue:5

    Topics: Amino Acid Sequence; Anilino Naphthalenesulfonates; Animals; Calcium; Elapid Venoms; Fluorescent Dyes; Lethal Dose 50; Lysine; Molecular Sequence Data; Neurotoxins; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Snakes; Spectrometry, Fluorescence; Structure-Activity Relationship

1996
Site-directed mutagenesis of the amino acid residues in beta-strand III [Val30-Val36] of D-amino acid aminotransferase of Bacillus sp. YM-1.
    FEBS letters, 1996, Dec-02, Volume: 398, Issue:2-3

    Topics: Alanine Transaminase; Bacillus; Binding Sites; D-Alanine Transaminase; Glutamic Acid; Hemiterpenes; Hydrogen Bonding; Hydrogen-Ion Concentration; Keto Acids; Ketoglutaric Acids; Kinetics; Lysine; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Spectrometry, Fluorescence; Valine

1996
Comparative study of pyridoxine-alpha, beta-glucosides, and phosphopyridoxyl-lysine as a vitamin B6 nutrient.
    Journal of nutritional science and vitaminology, 1996, Volume: 42, Issue:5

    Topics: Animal Nutritional Physiological Phenomena; Animals; Biological Transport; Glucosides; Intestinal Mucosa; Kidney; Liver; Lysine; Male; Pyridoxal Phosphate; Pyridoxine; Rats; Rats, Wistar; Vitamin B 6 Deficiency

1996
Monoclonal antibodies against Nalpha-(5'-phosphopyridoxyl)-L-lysine. Screening and spectrum of pyridoxal 5'-phosphate-dependent activities toward amino acids.
    The Journal of biological chemistry, 1997, Apr-11, Volume: 272, Issue:15

    Topics: Affinity Labels; Amino Acids; Antibodies, Monoclonal; Digitonin; Indicators and Reagents; Kinetics; Lysine; Models, Chemical; Pyridoxal Phosphate; Semicarbazides; Spectrometry, Fluorescence; Valine

1997
Substitutions of alanine for cysteine at a reactive thiol site and for lysine at a pyridoxal phosphate binding site of 1-aminocyclopropane-1-carboxylate deaminase.
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:3

    Topics: Absorption; Alanine; Base Sequence; Binding Sites; Carbon-Carbon Lyases; Catalysis; Cysteine; Escherichia coli; Gene Expression Regulation, Enzymologic; Lyases; Lysine; Mutagenesis, Site-Directed; Mutation; Plasmids; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Substrate Specificity; Sulfhydryl Compounds; Valine

1997
Modification of brain glutamate dehydrogenase isoproteins with pyridoxal 5'-phosphate.
    Biochimie, 1996, Volume: 78, Issue:10

    Topics: Animals; Borohydrides; Brain; Cattle; Cysteine; Enzyme Inhibitors; Enzyme Reactivators; Glutamate Dehydrogenase; Isoenzymes; Lysine; Pyridoxal Phosphate

1996
Site-directed mutagenesis in basic amino acid residues of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase.
    Journal of protein chemistry, 1997, Volume: 16, Issue:3

    Topics: Arginine; Binding Sites; Cloning, Molecular; Glutamine; Kinetics; Lysine; Mutagenesis, Site-Directed; Phosphoenolpyruvate Carboxykinase (GTP); Point Mutation; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Saccharomyces cerevisiae; Trypsin

1997
L-allo-threonine aldolase from Aeromonas jandaei DK-39: gene cloning, nucleotide sequencing, and identification of the pyridoxal 5'-phosphate-binding lysine residue by site-directed mutagenesis.
    Journal of bacteriology, 1997, Volume: 179, Issue:11

    Topics: Aeromonas; Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Genes, Bacterial; Glycine Hydroxymethyltransferase; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Sequence Alignment

1997
Essential active-site lysine of brain glutamate dehydrogenase isoproteins.
    Journal of neurochemistry, 1997, Volume: 69, Issue:1

    Topics: Animals; Binding Sites; Brain; Brain Chemistry; Cattle; Chromatography, High Pressure Liquid; Enzyme Activation; Glutamate Dehydrogenase; Humans; Isoenzymes; Ketoglutaric Acids; Lysine; NAD; Peptides; Protein Processing, Post-Translational; Pyridoxal Phosphate

1997
Modification of an essential amino group of glutathione reductase from yeast by pyridoxal 5'-phosphate.
    Journal of enzyme inhibition, 1997, Volume: 12, Issue:2

    Topics: Crystallography, X-Ray; Enzyme Inhibitors; Glutathione Disulfide; Glutathione Reductase; Hydrogen-Ion Concentration; Kinetics; Lysine; NADP; Pyridoxal Phosphate; Saccharomyces cerevisiae; Structure-Activity Relationship

1997
Are pyridoxal and fluorescein probes in lysine residues of alpha-chain in Na+,K(+)-ATPase sensing ATP binding?
    Annals of the New York Academy of Sciences, 1997, Nov-03, Volume: 834

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Fluorescent Dyes; Kidney; Kinetics; Lysine; Macromolecular Substances; Phosphorylation; Pyridoxal; Pyridoxal Phosphate; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence; Swine

1997
Feeding experiments of pyridoxine derivatives as vitamin B6.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1997, Volume: 67, Issue:6

    Topics: Animals; Aspartate Aminotransferases; Biological Availability; Diet; Erythrocytes; Glucosides; Hydrolases; Liver; Lysine; Male; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Rats; Rats, Wistar; Vitamin B 6 Deficiency; Weight Gain; Xanthurenates

1997
Analysis of the pH- and ligand-induced spectral transitions of tryptophanase: activation of the coenzyme at the early steps of the catalytic cycle.
    Biochemistry, 1998, Mar-03, Volume: 37, Issue:9

    Topics: Catalysis; Coenzymes; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Indoles; Ligands; Lysine; Models, Chemical; Propionates; Protein Conformation; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry, Atomic; Tryptophanase

1998
Mutational analysis of the role of the conserved lysine-270 in the Pichia stipitis xylose reductase.
    FEMS microbiology letters, 1998, Feb-01, Volume: 159, Issue:1

    Topics: Aldehyde Reductase; Coenzymes; DNA Mutational Analysis; DNA, Fungal; Lysine; Mutagenesis, Site-Directed; Pichia; Pyridoxal Phosphate; Substrate Specificity

1998
Fluorescein 5'-isothiocyanate-modified Na+, K+ -ATPase, at Lys-501 of the alpha-chain, accepts ATP independent of pyridoxal 5'-diphospho-5'-adenosine modification at Lys-480.
    Journal of biochemistry, 1998, Volume: 123, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Fluorescein-5-isothiocyanate; Lysine; Pyridoxal Phosphate; Sodium-Potassium-Exchanging ATPase

1998
Cystathionine gamma-synthase from Arabidopsis thaliana: purification and biochemical characterization of the recombinant enzyme overexpressed in Escherichia coli.
    The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2)

    Topics: Alkynes; Amino Acid Sequence; Arabidopsis; Binding Sites; Carbon-Oxygen Lyases; Cloning, Molecular; DNA, Complementary; Enzyme Inhibitors; Escherichia coli; Gene Expression; Glycine; Homoserine; Kinetics; Lysine; Macromolecular Substances; Methionine; Molecular Sequence Data; Pyridoxal Phosphate; Recombinant Proteins

1998
Chemical modification of the dihydropyridines binding sites by lysine reagent, pyridoxal 5'-phosphate.
    Neurochemistry international, 1998, Volume: 32, Issue:4

    Topics: Animals; Binding Sites; Calcium Channel Blockers; Dihydropyridines; Indicators and Reagents; Kinetics; Lysine; Nitrendipine; Pyridoxal Phosphate; Rabbits

1998
Chemical modification of dextransucrase from Leuconostoc mesenteroides NRRL B-512F by pyridoxal 5'-phosphate: evidence for the presence of an essential lysine residue at the active site.
    Biochemistry and molecular biology international, 1998, Volume: 44, Issue:6

    Topics: Binding Sites; Dextrans; Edetic Acid; Enzyme Activation; Glucose; Glucosyltransferases; Kinetics; Leuconostoc; Lysine; Pyridoxal Phosphate; Spectrometry, Fluorescence; Sucrose

1998
Inactivation of enoyl-CoA reductase in pigeon liver fatty acid synthetase by pyridoxal 5'-phosphate: evidence for the presence of one lysine residue at the active site.
    Journal of enzyme inhibition, 1998, Volume: 13, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Binding Sites; Columbidae; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Fatty Acid Synthases; Kinetics; Liver; Lysine; Malonyl Coenzyme A; Oxidoreductases; Pyridoxal Phosphate; Spectrometry, Fluorescence

1998
Identification of lysine-238 of Escherichia coli biotin carboxylase as an ATP-binding residue.
    FEBS letters, 1998, May-15, Volume: 427, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Binding Sites; Carbon-Nitrogen Ligases; Escherichia coli; Lysine; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Structure-Activity Relationship

1998
Recognition of core-type DNA sites by lambda integrase.
    Journal of molecular biology, 1998, Jun-12, Volume: 279, Issue:3

    Topics: Bacteriophage lambda; Binding Sites; Coliphages; Cross-Linking Reagents; DNA; DNA-Binding Proteins; Integrases; Kinetics; Lysine; Metalloendopeptidases; Oligodeoxyribonucleotides; Peptide Fragments; Pyridoxal Phosphate; Ultraviolet Rays

1998
Half-site modification of Lys-480 of the Na+,K+-ATPase alpha-chain with pyridoxal 5'-diphospho-5'-adenosine reduces ATP-dependent phosphorylation stoichiometry from half to a quarter.
    The Journal of biological chemistry, 1998, Sep-18, Volume: 273, Issue:38

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Dogs; Kidney; Kinetics; Lysine; Macromolecular Substances; Magnesium; Models, Structural; Phosphorylation; Pyridoxal Phosphate; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Time Factors

1998
Inhibition of camel lens zeta-crystallin/NADPH:quinone oxidoreductase by pyridoxal-5'-phosphate.
    Biochimica et biophysica acta, 1998, Oct-14, Volume: 1388, Issue:1

    Topics: Animals; Binding Sites; Camelus; Crystallins; Enzyme Inhibitors; Kinetics; Lysine; NAD(P)H Dehydrogenase (Quinone); o-Phthalaldehyde; Pyridoxal Phosphate; zeta-Crystallins

1998
The imine-pyridine torsion of the pyridoxal 5'-phosphate Schiff base of aspartate aminotransferase lowers its pKa in the unliganded enzyme and is crucial for the successive increase in the pKa during catalysis.
    Biochemistry, 1998, Oct-27, Volume: 37, Issue:43

    Topics: Alanine; Aspartate Aminotransferases; Binding Sites; Catalysis; Energy Transfer; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Ligands; Lysine; N-Methylaspartate; Protein Conformation; Protons; Pyridines; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry; Thermodynamics

1998
Lysine-691 of the anion exchanger from human erythrocytes is located on its cytoplasmic surface.
    The Biochemical journal, 1998, Dec-01, Volume: 336 ( Pt 2)

    Topics: Anion Exchange Protein 1, Erythrocyte; Chromatography, High Pressure Liquid; Cytoplasm; Erythrocytes; Humans; Immunochemistry; Lysine; Peptide Fragments; Pyridoxal Phosphate

1998
Studies on the amino acid residues of the active site of alpha-aspartyl dipeptidase.
    Annals of the New York Academy of Sciences, 1998, Dec-13, Volume: 864

    Topics: Arginine; Binding Sites; Catalytic Domain; Diethyl Pyrocarbonate; Dipeptidases; Escherichia coli; Kinetics; Lysine; Phenylglyoxal; Pyridoxal Phosphate; Salmonella typhimurium

1998
Role of lysine 39 of alanine racemase from Bacillus stearothermophilus that binds pyridoxal 5'-phosphate. Chemical rescue studies of Lys39 --> Ala mutant.
    The Journal of biological chemistry, 1999, Feb-12, Volume: 274, Issue:7

    Topics: Alanine; Alanine Racemase; Amino Acid Substitution; Catalysis; Circular Dichroism; Geobacillus stearothermophilus; Lysine; Models, Chemical; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship

1999
Binding of pyridoxal 5'-phosphate to the heme protein human cystathionine beta-synthase.
    Biochemistry, 1999, Mar-02, Volume: 38, Issue:9

    Topics: Binding Sites; Borohydrides; Cystathionine beta-Synthase; Enzyme Activation; Hemeproteins; Humans; Hydroxylamine; Imines; Lysine; Oxidation-Reduction; Oximes; Pyridoxal Phosphate; Recombinant Proteins; Substrate Specificity

1999
Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase.
    Biochemistry, 1999, Mar-16, Volume: 38, Issue:11

    Topics: Alanine Racemase; Arginine; Binding Sites; Carboxylic Acids; Computer Simulation; Crystallography, X-Ray; Geobacillus stearothermophilus; Hydrogen Bonding; Kinetics; Lysine; Models, Molecular; Propionates; Pyridoxal Phosphate; Schiff Bases; Substrate Specificity

1999
Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase.
    Biochemistry, 1999, Mar-30, Volume: 38, Issue:13

    Topics: Alanine Racemase; Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Geobacillus stearothermophilus; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Protons; Pyridoxal Phosphate; Schiff Bases; Solvents; Tyrosine

1999
Chemical modification of NADP-isocitrate dehydrogenase from Cephalosporium acremonium evidence of essential histidine and lysine groups at the active site.
    European journal of biochemistry, 1999, Volume: 261, Issue:3

    Topics: Acremonium; Binding Sites; Diethyl Pyrocarbonate; Enzyme Inhibitors; Enzyme Reactivators; Histidine; Hydroxylamine; Isocitrate Dehydrogenase; Kinetics; Lysine; Pyridoxal Phosphate

1999
Chemical modification of lysine and arginine residues of bovine heart 2-oxoglutarate dehydrogenase: effect on the enzyme activity and regulation.
    Acta biochimica Polonica, 1998, Volume: 45, Issue:4

    Topics: Adenosine Diphosphate; Animals; Arginine; Cattle; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ketoglutarate Dehydrogenase Complex; Kinetics; Lysine; Myocardium; Phenylglyoxal; Pyridoxal Phosphate; Thiamine Pyrophosphate; Time Factors

1998
Identification of Arg-12 in the active site of Escherichia coli K1 CMP-sialic acid synthetase.
    The Biochemical journal, 1999, Oct-15, Volume: 343 Pt 2

    Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Arginine; Binding Sites; Conserved Sequence; Cytidine Triphosphate; Enzyme Stability; Escherichia coli; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Acylneuraminate Cytidylyltransferase; Oxidation-Reduction; Protein Denaturation; Pyridoxal Phosphate; Recombinant Fusion Proteins; Sequence Alignment; Thermodynamics

1999
Lysine-69 plays a key role in catalysis by ornithine decarboxylase through acceleration of the Schiff base formation, decarboxylation, and product release steps.
    Biochemistry, 1999, Sep-07, Volume: 38, Issue:36

    Topics: Animals; Base Sequence; Carboxylic Acids; Catalysis; Circular Dichroism; DNA Primers; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Ornithine Decarboxylase; Protein Binding; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry, Ultraviolet; Trypanosoma brucei brucei

1999
Rhodobacter sphaeroides phosphoribulokinase: identification of lysine-165 as a catalytic residue and evaluation of the contributions of invariant basic amino acids to ribulose 5-phosphate binding.
    Biochemistry, 1999, Oct-19, Volume: 38, Issue:42

    Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cysteine; Gluconates; Kinetics; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphotransferases (Alcohol Group Acceptor); Pyridoxal Phosphate; Rhodobacter sphaeroides; Ribulosephosphates

1999
Inactivation of the reconstituted oxoglutarate carrier from bovine heart mitochondria by pyridoxal 5'-phosphate.
    Journal of bioenergetics and biomembranes, 1999, Volume: 31, Issue:6

    Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Cattle; Ketoglutaric Acids; Kinetics; Liposomes; Lysine; Membrane Transport Proteins; Mitochondria, Heart; Pyridoxal Phosphate; Tritium

1999
Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
    Journal of molecular biology, 2000, Mar-24, Volume: 297, Issue:2

    Topics: Allylglycine; Bacterial Proteins; Binding Sites; Catalysis; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Dimerization; Histidine; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Lyases; Lysine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Structure, Secondary; Pyridoxal Phosphate; Selenomethionine; Spectrophotometry; Sulfur; Thermotoga maritima; Transaminases

2000
Oxidation of human alpha-thrombin by the myeloperoxidase-H2O2-chloride system: structural and functional effects.
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:2

    Topics: Amino Acid Sequence; Antithrombin III; Blood Platelets; Chlorides; Chromatography, High Pressure Liquid; Fibrinopeptide A; Fibrinopeptide B; Hemostatics; Heparin; Humans; Hydrogen Peroxide; Hydrolysis; Hypochlorous Acid; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptides; Peroxidase; Platelet Activation; Protein C; Pyridoxal Phosphate; Structure-Activity Relationship; Substrate Specificity; Thrombin; Thrombomodulin

2000
Cloning and characterization of the ddc homolog encoding L-2,4-diaminobutyrate decarboxylase in Enterobacter aerogenes.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:5

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carboxy-Lyases; Cloning, Molecular; DNA, Bacterial; Enterobacter; Enterobacteriaceae; Intercellular Signaling Peptides and Proteins; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Organometallic Compounds; Peptides; Pyridoxal Phosphate; Sequence Homology, Amino Acid

2000
A GDP-fucose-protected, pyridoxal-5'-Phosphate/NaBH(4)-sensitive lys residue common to human alpha1-->3Fucosyltransferases corresponds to Lys(300) in FucT-IV.
    Biochemical and biophysical research communications, 2000, Jul-14, Volume: 273, Issue:3

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Borohydrides; COS Cells; DNA Primers; Fucosyltransferases; Guanosine Diphosphate Fucose; Humans; Kinetics; Lysine; Molecular Sequence Data; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Substrate Specificity

2000
Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
    Biochemistry, 2001, Jan-16, Volume: 40, Issue:2

    Topics: Arginine; Asparagine; Aspartate Aminotransferases; Catalytic Domain; Crystallography, X-Ray; Dicarboxylic Acids; DNA Mutational Analysis; Escherichia coli; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Ligands; Lysine; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Schiff Bases; Static Electricity; Structure-Activity Relationship

2001
Identification of lysine 346 as a functionally important residue for pyridoxal 5'-phosphate binding and catalysis in lysine 2, 3-aminomutase from Bacillus subtilis.
    Biochemistry, 2001, Jan-16, Volume: 40, Issue:2

    Topics: Bacillus subtilis; Binding Sites; Borohydrides; Catalysis; Gas Chromatography-Mass Spectrometry; Glutamine; Intramolecular Transferases; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Peptide Fragments; Pyridoxal Phosphate; Reducing Agents; Spectrophotometry, Ultraviolet

2001
Amino acid sequences and hapten binding of catalytic and noncatalytic antibodies against N(alpha)-(5'-phosphopyridoxyl)-L-lysine.
    Molecular immunology, 2000, Volume: 37, Issue:11

    Topics: Amino Acid Sequence; Antibodies, Monoclonal; Catalysis; Haptens; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Lysine; Molecular Sequence Data; Pyridoxal Phosphate

2000
Occurrence of D-Amino Acids and a pyridoxal 5'-phosphate-dependent aspartate racemase in the acidothermophilic archaeon, Thermoplasma acidophilum.
    Biochemical and biophysical research communications, 2001, Feb-23, Volume: 281, Issue:2

    Topics: Alanine; Amino Acid Isomerases; Amino Acids; Aspartic Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylmaleimide; Glutamic Acid; Leucine; Lysine; Phenylalanine; Pyridoxal Phosphate; Stereoisomerism; Thermoplasma

2001
Effect of phosphate on stability of pyridoxal in the presence of lysine.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:3

    Topics: Drug Stability; Kinetics; Lysine; Phosphates; Pyridoxal; Pyridoxal Phosphate; Schiff Bases; Solutions; Spectrometry, Mass, Fast Atom Bombardment; Water

2001
Inhibitory effect of glycation on catalytic activity of alanine aminotransferase.
    Molecular and cellular biochemistry, 2001, Volume: 218, Issue:1-2

    Topics: Alanine; Alanine Transaminase; Animals; Catalysis; Enzyme Activation; Fructose; Glucose; Glyceraldehyde; In Vitro Techniques; Ketoglutaric Acids; Lysine; Myocardium; Pharmacology; Pyridoxal Phosphate; Ribose; Swine; Time Factors

2001
Inhibitors of advanced glycation end product-associated protein cross-linking.
    Biochimica et biophysica acta, 2001, Feb-14, Volume: 1535, Issue:2

    Topics: Animals; Carbon Radioisotopes; Cattle; Cross-Linking Reagents; Crystallins; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescence; Glucose; Glycation End Products, Advanced; Glycosylation; Lysine; Pyridoxal Phosphate; Sulfites; Tetroses; Thiamine Pyrophosphate

2001
Cassette mutagenesis of lysine 130 of human glutamate dehydrogenase. An essential residue in catalysis.
    European journal of biochemistry, 2001, Volume: 268, Issue:11

    Topics: Amino Acid Sequence; Base Sequence; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Glutamate Dehydrogenase; Humans; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Insertional; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

2001
Identification of a critical lysine residue at the active site in glyceraldehyde-3-phosphate dehydrogenase of Ehrlich ascites carcinoma cell. Comparison with the rabbit muscle enzyme.
    European journal of biochemistry, 2001, Volume: 268, Issue:23

    Topics: Amino Acid Sequence; Animals; Carcinoma, Ehrlich Tumor; Catalytic Domain; Dithionitrobenzoic Acid; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); In Vitro Techniques; Kinetics; Lysine; Mice; Molecular Sequence Data; Muscles; Protein Subunits; Pyridoxal Phosphate; Rabbits; Trinitrobenzenesulfonic Acid

2001
Inhibition of camel lens zeta-crystallin by aspirin and aspirin-like analgesics.
    The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:1

    Topics: Acetaminophen; Analgesics; Animals; Aspirin; Binding Sites; Binding, Competitive; Camelus; Crystallins; Ibuprofen; In Vitro Techniques; Kinetics; Lysine; NADP; Phenanthrenes; Pyridoxal Phosphate

2002
Pyridoxal 5-phosphate inhibition of substrate selectivity mutants of UhpT, the sugar 6-phosphate carrier of Escherichia coli.
    Journal of bacteriology, 2002, Volume: 184, Issue:13

    Topics: Escherichia coli Proteins; Lysine; Monosaccharide Transport Proteins; Mutation; Phosphoenolpyruvate; Pyridoxal Phosphate; Substrate Specificity

2002
Contribution of Lys276 to the conformational flexibility of the active site of glutamate decarboxylase from Escherichia coli.
    European journal of biochemistry, 2002, Volume: 269, Issue:20

    Topics: Binding Sites; Circular Dichroism; Escherichia coli Proteins; Glutamate Decarboxylase; Glutamic Acid; Lysine; Mutation; Protein Conformation; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry

2002
Lysine 238 is an essential residue for alpha,beta-elimination catalyzed by Treponema denticola cystalysin.
    The Journal of biological chemistry, 2003, Sep-26, Volume: 278, Issue:39

    Topics: Catalysis; Circular Dichroism; Cystathionine gamma-Lyase; Lysine; Pyridoxal Phosphate; Treponema

2003
Visualization of PLP-bound intermediates in hemeless variants of human cystathionine beta-synthase: evidence that lysine 119 is a general base.
    Archives of biochemistry and biophysics, 2004, Jul-15, Volume: 427, Issue:2

    Topics: Binding Sites; Cystathionine beta-Synthase; Enzyme Activation; Genetic Variation; Heme; Humans; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry, Ultraviolet; Stereoisomerism

2004
Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase.
    Biochemistry, 2004, Oct-19, Volume: 43, Issue:41

    Topics: Alanine; Animals; Binding Sites; Crystallization; Crystallography, X-Ray; Diamines; Dimerization; Kinetics; Lysine; Mutagenesis, Site-Directed; Ornithine; Ornithine Decarboxylase; Protein Conformation; Putrescine; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Trypanosoma brucei brucei

2004
Pyridoxal 5'-phosphate inactivates DNA topoisomerase IB by modifying the lysine general acid.
    Nucleic acids research, 2004, Volume: 32, Issue:18

    Topics: Adenosine Diphosphate; Binding Sites; DNA Topoisomerases, Type I; Enzyme Inhibitors; Humans; Lysine; Models, Molecular; Pyridoxal Phosphate

2004
Role of lysine-256 in Citrobacter freundii tyrosine phenol-lyase in monovalent cation activation.
    Biochemistry, 2004, Nov-16, Volume: 43, Issue:45

    Topics: Alanine; Animals; Arginine; Aspartic Acid; Cations, Monovalent; Citrobacter freundii; Enzyme Activation; Glutamic Acid; Histidine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Potassium; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Tyrosine Phenol-Lyase

2004
Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration.
    The Journal of biological chemistry, 2005, Feb-11, Volume: 280, Issue:6

    Topics: Aldehyde Oxidase; Arabidopsis; Arabidopsis Proteins; Bacterial Proteins; Binding Sites; Catalysis; Coenzymes; Cysteine; Cytosol; Fluorescent Dyes; Genetic Vectors; Iron-Sulfur Proteins; Kinetics; Lyases; Lysine; Metalloproteins; Molybdenum; Molybdenum Cofactors; Mutagenesis, Site-Directed; Naphthalenesulfonates; Pichia; Plant Proteins; Protein Binding; Protein Structure, Tertiary; Pteridines; Pyridoxal Phosphate; Selenocysteine; Spectrophotometry; Substrate Specificity; Sulfides; Sulfurtransferases; Xanthine Dehydrogenase

2005
Mass spectrometric analysis of the HIV-1 integrase-pyridoxal 5'-phosphate complex reveals a new binding site for a nucleotide inhibitor.
    The Journal of biological chemistry, 2005, Mar-04, Volume: 280, Issue:9

    Topics: Amino Acid Sequence; Binding Sites; Cell Line, Tumor; Cross-Linking Reagents; DNA; DNA, Viral; Electrophoresis, Polyacrylamide Gel; HIV Integrase; Humans; Inhibitory Concentration 50; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction

2005
Lys-64 of the A chain is involved in the enzymatic activity and neurotoxic effect of beta-bungarotoxin.
    Toxicon : official journal of the International Society on Toxinology, 2005, Volume: 45, Issue:2

    Topics: Amino Acid Sequence; Animals; Bungarotoxins; Chickens; Electrophysiology; In Vitro Techniques; Lysine; Molecular Sequence Data; Muscle Contraction; Neuromuscular Junction; Neurotoxins; Protein Conformation; Pyridoxal Phosphate; Snake Venoms; Xenopus

2005
Site-directed mutagenesis of human brain GABA transaminase: lysine-357 is involved in cofactor binding at the active site.
    Molecules and cells, 2004, Dec-31, Volume: 18, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Amino Acid Sequence; Base Sequence; Binding Sites; Brain; Catalysis; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Humans; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry

2004
Inactivation of brain myo-inositol monophosphate phosphatase by pyridoxal-5'-phosphate.
    Journal of biochemistry and molecular biology, 2005, Jan-31, Volume: 38, Issue:1

    Topics: Amino Acids; Animals; Binding Sites; Borohydrides; Brain; Catalysis; Chromatography, High Pressure Liquid; Enzyme Activation; Inositol Phosphates; Lysine; Oxidation-Reduction; Peptide Fragments; Phenylthiohydantoin; Phosphoric Monoester Hydrolases; Protein Binding; Pyridoxal Phosphate; Swine; Time Factors

2005
Effects of chemical modification of lysine residues on the sweetness of lysozyme.
    Chemical senses, 2005, Volume: 30, Issue:3

    Topics: Acetylation; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Guanidines; Lysine; Muramidase; Pyridoxal Phosphate; Structure-Activity Relationship; Sweetening Agents; Taste

2005
Mice have a transcribed L-threonine aldolase/GLY1 gene, but the human GLY1 gene is a non-processed pseudogene.
    BMC genomics, 2005, Mar-09, Volume: 6

    Topics: Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Cloning, Molecular; Codon, Terminator; Computational Biology; Crystallography, X-Ray; DNA, Complementary; Embryo, Mammalian; Exons; Gene Deletion; Gene Expression Regulation, Developmental; Glycine Hydroxymethyltransferase; Humans; Liver; Lysine; Mice; Molecular Sequence Data; Open Reading Frames; Protein Structure, Tertiary; Pseudogenes; Pyridoxal Phosphate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Time Factors; Tissue Distribution; Transcription, Genetic

2005
Biochemical characterization of the Campylobacter jejuni Cj1294, a novel UDP-4-keto-6-deoxy-GlcNAc aminotransferase that generates UDP-4-amino-4,6-dideoxy-GalNAc.
    The Journal of biological chemistry, 2005, May-27, Volume: 280, Issue:21

    Topics: Acetylglucosamine; Arginine; Bacterial Proteins; Campylobacter jejuni; Cloning, Molecular; Dimerization; Enzyme Stability; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Transaminases; Uridine Diphosphate N-Acetylgalactosamine

2005
Role of Lys-226 in the catalytic mechanism of Bacillus stearothermophilus serine hydroxymethyltransferase--crystal structure and kinetic studies.
    Biochemistry, 2005, May-10, Volume: 44, Issue:18

    Topics: Amination; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Geobacillus stearothermophilus; Glycine Hydroxymethyltransferase; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Quinones; Semicarbazides; Spectrophotometry, Ultraviolet; Substrate Specificity; Tetrahydrofolates

2005
Strain relief at the active site of phosphoserine aminotransferase induced by radiation damage.
    Protein science : a publication of the Protein Society, 2005, Volume: 14, Issue:6

    Topics: Bacillus; Crystallography, X-Ray; Lysine; Pyridoxal Phosphate; Schiff Bases; Transaminases

2005
Substrate recognition by the human fatty-acid synthase.
    The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Allosteric Site; Antineoplastic Agents; Binding Sites; DNA Primers; Fatty Acid Desaturases; Fatty Acid Synthases; Humans; Kinetics; Lysine; Models, Chemical; Mutagenesis; Mutation; NADP; Protein Binding; Pyridoxal Phosphate; Spectrometry, Fluorescence; Substrate Specificity

2005
Relationships of Cysteine and Lysine residues with the substrate binding site of the mitochondrial ornithine/citrulline carrier: an inhibition kinetic approach combined with the analysis of the homology structural model.
    Biochimica et biophysica acta, 2005, Dec-10, Volume: 1718, Issue:1-2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Transport Systems, Basic; Animals; Binding Sites; Biological Transport; Citrulline; Cysteine; Lysine; Mutation; Ornithine; Protein Conformation; Pyridoxal Phosphate; Rats; Structural Homology, Protein; Sulfhydryl Reagents

2005
Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of pseudaminic acid, an essential flagellar modification in Helicobacter pylori.
    The Journal of biological chemistry, 2006, Mar-31, Volume: 281, Issue:13

    Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Electrophoresis, Capillary; Electrophoresis, Polyacrylamide Gel; Flagella; Glycosylation; Helicobacter pylori; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Ligands; Light; Lysine; Models, Biological; Models, Molecular; Molecular Structure; Mutagenesis, Insertional; Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Pyridoxal Phosphate; Scattering, Radiation; Spectrum Analysis, Raman; Substrate Specificity; Transaminases

2006
Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia.
    Journal of molecular biology, 2007, Aug-17, Volume: 371, Issue:3

    Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Catalysis; Chlamydia; Crystallography, X-Ray; Diaminopimelic Acid; Dimerization; Glutamic Acid; Lysine; Malates; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Protein Subunits; Pyridoxal Phosphate; Sequence Alignment; Sequence Homology, Amino Acid; Solvents; Static Electricity; Substrate Specificity; Transaminases

2007
DNA damage during glycation of lysine by methylglyoxal: assessment of vitamins in preventing damage.
    Amino acids, 2007, Volume: 33, Issue:4

    Topics: Amino Acids; DNA Damage; Free Radical Scavengers; Glycation End Products, Advanced; Glycosylation; Iron; Lysine; Plasmids; Pyridoxal Phosphate; Pyruvaldehyde; Superoxides; Vitamins

2007
Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme.
    BMC biochemistry, 2008, Jun-19, Volume: 9

    Topics: Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Evolution, Molecular; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Recombinant Proteins; Ribonuclease, Pancreatic; Vitamin B 6

2008
Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
    Journal of molecular biology, 2008, Dec-31, Volume: 384, Issue:5

    Topics: Apoenzymes; Arabidopsis; Arabidopsis Proteins; Catalysis; Catalytic Domain; Crystallography, X-Ray; Diaminopimelic Acid; Glutamic Acid; Lysine; Models, Molecular; Mutant Proteins; Oxidation-Reduction; Protein Structure, Secondary; Pyridoxal Phosphate; Static Electricity; Substrate Specificity

2008
The yeast mitochondrial citrate transport protein: identification of the Lysine residues responsible for inhibition mediated by Pyridoxal 5'-phosphate.
    Journal of bioenergetics and biomembranes, 2008, Volume: 40, Issue:6

    Topics: Binding Sites; Carrier Proteins; Computer Simulation; Fungal Proteins; Lysine; Mitochondria; Models, Chemical; Models, Molecular; Protein Binding; Pyridoxal Phosphate; Structure-Activity Relationship

2008
Gene cloning and expression of pyridoxal 5'-phosphate-dependent L-threo-3-hydroxyaspartate dehydratase from Pseudomonas sp. T62, and characterization of the recombinant enzyme.
    Journal of biochemistry, 2009, Volume: 145, Issue:5

    Topics: Amino Acid Sequence; Amino Acids; Base Sequence; Catalytic Domain; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Genes, Bacterial; Hydro-Lyases; Hydrogen-Ion Concentration; Lysine; Metals; Molecular Sequence Data; Molecular Weight; Nucleotides; Phylogeny; Pseudomonas; Pyridoxal Phosphate; Recombinant Proteins; Sequence Alignment; Spectrum Analysis; Substrate Specificity; Temperature

2009
A periplasmic, pyridoxal-5'-phosphate-dependent amino acid racemase in Pseudomonas taetrolens.
    Applied microbiology and biotechnology, 2009, Volume: 83, Issue:6

    Topics: Amino Acid Isomerases; Arginine; Bacterial Proteins; DNA, Bacterial; Escherichia coli; Lysine; Molecular Sequence Data; Ornithine; Periplasm; Protein Processing, Post-Translational; Protein Transport; Pseudomonas; Pyridoxal Phosphate; Recombinant Proteins; Sequence Analysis, DNA; Sequence Analysis, Protein

2009
Structure, assembly, and mechanism of a PLP-dependent dodecameric L-aspartate beta-decarboxylase.
    Structure (London, England : 1993), 2009, Apr-15, Volume: 17, Issue:4

    Topics: Alcaligenes; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Carboxy-Lyases; Crystallization; Crystallography, X-Ray; Dimerization; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Pseudomonas; Pyridoxal Phosphate; Substrate Specificity

2009
Multiple roles of the active site lysine of Dopa decarboxylase.
    Archives of biochemistry and biophysics, 2009, Aug-15, Volume: 488, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alanine; Amino Acid Substitution; Ammonia; Animals; Binding Sites; Catalysis; Deamination; Decarboxylation; Dopa Decarboxylase; Dopamine; Hydrogen Bonding; Hydrolysis; Kidney; Kinetics; Levodopa; Lysine; Models, Chemical; Molecular Structure; Oxidation-Reduction; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship; Swine

2009
Pyridoxal 5'-phosphate binding in lysine-modified PAMAM dendrimers: a biomimetic approach.
    Organic letters, 2009, Aug-20, Volume: 11, Issue:16

    Topics: Binding Sites; Dendrimers; Hydrogen-Ion Concentration; Lysine; Molecular Structure; Peptides; Phenylalanine; Polyamines; Pyridoxal Phosphate

2009
Purification, characterization and amino acid sequence of a novel enzyme, D-threo-3-hydroxyaspartate dehydratase, from Delftia sp. HT23.
    Journal of biochemistry, 2010, Volume: 148, Issue:6

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Catalytic Domain; Cloning, Molecular; Delftia; Escherichia coli; Hydro-Lyases; Kinetics; Lysine; Metals, Heavy; Molecular Sequence Data; Molecular Weight; Pyridoxal Phosphate; Recombinant Proteins; Sequence Alignment; Substrate Specificity; Temperature

2010
NMR studies of the stability, protonation States, and tautomerism of (13)C- AND (15)N-labeled aldimines of the coenzyme pyridoxal 5'-phosphate in water.
    Biochemistry, 2010, Dec-28, Volume: 49, Issue:51

    Topics: Carbon Isotopes; Diamines; Hydrogen-Ion Concentration; Isomerism; Lysine; Molecular Structure; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protons; Pyridoxal Phosphate; Schiff Bases; Thermodynamics; Water

2010
Suppression of isotope scrambling in cell-free protein synthesis by broadband inhibition of PLP enymes for selective 15N-labelling and production of perdeuterated proteins in H2O.
    Journal of biomolecular NMR, 2011, Volume: 50, Issue:1

    Topics: Cell-Free System; Deuterium; Isotope Labeling; Lysine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Biosynthesis; Proteins; Pyridoxal Phosphate; Water

2011
Endo-inulinase stabilization by pyridoxal phosphate modification: a kinetics, thermodynamics, and simulation approach.
    Applied biochemistry and biotechnology, 2011, Volume: 165, Issue:7-8

    Topics: Enzyme Stability; Glycoside Hydrolases; Kinetics; Lysine; Pyridoxal Phosphate; Substrate Specificity; Temperature; Thermodynamics

2011
Quantum chemistry studies of the catalysis mechanism differences between the two isoforms of glutamic acid decarboxylase.
    Journal of molecular modeling, 2013, Volume: 19, Issue:2

    Topics: Biocatalysis; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Isoenzymes; Kinetics; Lysine; Protein Structure, Secondary; Protons; Pyridoxal Phosphate; Quantum Theory; Thermodynamics; Tyrosine

2013
Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis.
    Acta crystallographica. Section F, Structural biology and crystallization communications, 2013, Feb-01, Volume: 69, Issue:Pt 2

    Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Coenzymes; Crystallography, X-Ray; Diaminopimelic Acid; Lysine; Molecular Sequence Data; Pyridoxal Phosphate; Sequence Alignment; Species Specificity; Structural Homology, Protein; Substrate Specificity; Transaminases

2013
Crystal structure of Saccharomyces cerevisiae Aro8, a putative α-aminoadipate aminotransferase.
    Protein science : a publication of the Protein Society, 2013, Volume: 22, Issue:10

    Topics: 2-Aminoadipate Transaminase; Catalytic Domain; Crystallography, X-Ray; HEPES; Humans; Lysine; Models, Molecular; Protein Structure, Tertiary; Pyridoxal Phosphate; Pyridoxamine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Thermus thermophilus; Transaminases

2013
Characterization of a pyridoxal-5'-phosphate-dependent l-lysine decarboxylase/oxidase from Burkholderia sp. AIU 395.
    Journal of bioscience and bioengineering, 2014, Volume: 118, Issue:5

    Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Burkholderia; Carboxy-Lyases; Coenzymes; Decarboxylation; Escherichia coli; Isoelectric Point; Lysine; Molecular Sequence Data; Molecular Weight; Oxidation-Reduction; Protein Conformation; Pyridoxal Phosphate; Substrate Specificity

2014
A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes.
    The Journal of biological chemistry, 2014, Dec-05, Volume: 289, Issue:49

    Topics: Amino Acid Sequence; Bacterial Proteins; Biocatalysis; Clostridium sticklandii; Escherichia coli; Free Radicals; Hydrophobic and Hydrophilic Interactions; Intramolecular Transferases; Kinetics; Lysine; Molecular Conformation; Molecular Dynamics Simulation; Molecular Sequence Data; Mutagenesis, Site-Directed; Ornithine; Pyridoxal Phosphate; Recombinant Proteins; Static Electricity; Vitamin B 12

2014
Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase.
    The Journal of biological chemistry, 2015, Feb-27, Volume: 290, Issue:9

    Topics: Ammonia; Aspartic Acid; Bacterial Proteins; Biocatalysis; Biosynthetic Pathways; Catalytic Domain; Crystallography, X-Ray; Geobacillus stearothermophilus; Glutaminase; Glutamine; Glyceraldehyde 3-Phosphate; Kinetics; Lysine; Models, Molecular; Molecular Structure; Mutation; Protein Conformation; Pyridoxal Phosphate; Ribosemonophosphates; Spectrometry, Mass, Electrospray Ionization

2015
Optimization of Direct Lysine Decarboxylase Biotransformation for Cadaverine Production with Whole-Cell Biocatalysts at High Lysine Concentration.
    Journal of microbiology and biotechnology, 2015, Volume: 25, Issue:7

    Topics: Biotransformation; Cadaverine; Carboxy-Lyases; Escherichia coli; Gene Expression; Lysine; Metabolic Engineering; Pyridoxal Phosphate

2015
Mouse lysine catabolism to aminoadipate occurs primarily through the saccharopine pathway; implications for pyridoxine dependent epilepsy (PDE).
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:1

    Topics: 2-Aminoadipic Acid; Animals; Epilepsy; Female; Lysine; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Picolinic Acids; Pyridoxal Phosphate

2017
Chemical Mechanism of the Branched-Chain Aminotransferase IlvE from Mycobacterium tuberculosis.
    Biochemistry, 2016, Nov-15, Volume: 55, Issue:45

    Topics: Bacterial Proteins; Biocatalysis; Biosynthetic Pathways; Catalytic Domain; Glutamic Acid; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Lysine; Models, Chemical; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Protein Conformation; Pyridoxal Phosphate; Transaminases; Valine

2016
Lysine Restriction and Pyridoxal Phosphate Administration in a NADK2 Patient.
    Pediatrics, 2016, Volume: 138, Issue:5

    Topics: Child; Diet; Epilepsies, Myoclonic; Female; Homozygote; Humans; Hyperlysinemias; Lactic Acid; Lysine; Mitochondrial Diseases; Mitochondrial Proteins; Mutation; Nervous System Malformations; Phosphotransferases (Alcohol Group Acceptor); Pipecolic Acids; Pyridoxal Phosphate; RNA, Messenger; Vitamin B Complex

2016
Lysine Decarboxylase with an Enhanced Affinity for Pyridoxal 5-Phosphate by Disulfide Bond-Mediated Spatial Reconstitution.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Binding Sites; Cadaverine; Carboxy-Lyases; Catalytic Domain; Disulfides; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Mutation; Protein Conformation; Pyridoxal Phosphate; Selenomonas; Structure-Activity Relationship; Substrate Specificity

2017
Biotransformation of pyridoxal 5'-phosphate from pyridoxal by pyridoxal kinase (pdxY) to support cadaverine production in Escherichia coli.
    Enzyme and microbial technology, 2017, Volume: 104

    Topics: Biotechnology; Biotransformation; Cadaverine; Carboxy-Lyases; Cells, Immobilized; Escherichia coli; Escherichia coli Proteins; Lysine; Pyridoxal; Pyridoxal Kinase; Pyridoxal Phosphate

2017
Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis.
    Scientific reports, 2017, 09-15, Volume: 7, Issue:1

    Topics: Alanine; Catalysis; Catalytic Domain; Humans; Lysine; Models, Molecular; Molecular Structure; Protons; Pyridoxal Phosphate; Schiff Bases; Transaminases; X-Rays

2017
Structural basis for substrate specificity of meso-diaminopimelic acid decarboxylase from Corynebacterium glutamicum.
    Biochemical and biophysical research communications, 2018, 01-08, Volume: 495, Issue:2

    Topics: Amino Acid Sequence; Bacterial Proteins; Carboxy-Lyases; Catalytic Domain; Corynebacterium glutamicum; Crystallography, X-Ray; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Quaternary; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Substrate Specificity

2018
Magnetic field effects on coenzyme B
    Physical chemistry chemical physics : PCCP, 2018, May-09, Volume: 20, Issue:18

    Topics: Clostridium sticklandii; Cobamides; Electron Spin Resonance Spectroscopy; Free Radicals; Intramolecular Transferases; Kinetics; Lysine; Magnetic Fields; Models, Chemical; Pyridoxal Phosphate; Recombinant Proteins; Stereoisomerism

2018
Elucidation of the d-lysine biosynthetic pathway in the hyperthermophile Thermotoga maritima.
    The FEBS journal, 2019, Volume: 286, Issue:3

    Topics: Alanine; Amino Acid Isomerases; Amino Acid Sequence; Cell Wall; Cloning, Molecular; Coenzymes; Enzyme Assays; Escherichia coli; Gene Expression; Gene Expression Regulation, Bacterial; Genetic Vectors; Kinetics; Lysine; Metabolic Networks and Pathways; Ornithine; Peptidoglycan; Protein Multimerization; Pyridoxal Phosphate; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Stereoisomerism; Substrate Specificity; Thermotoga maritima

2019
Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase.
    Scientific reports, 2019, 11-18, Volume: 9, Issue:1

    Topics: Catalytic Domain; Chromobacterium; Crystallography, X-Ray; Lysine; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Multimerization; Protein Stability; Pyridoxal Phosphate; Schiff Bases; Transaminases

2019
Integrated gene engineering synergistically improved substrate-product transport, cofactor generation and gene translation for cadaverine biosynthesis in E. coli.
    International journal of biological macromolecules, 2021, Feb-01, Volume: 169

    Topics: Antiporters; Biotransformation; Cadaverine; Escherichia coli; Escherichia coli Proteins; Genetic Engineering; Lysine; Metabolic Engineering; Protein Biosynthesis; Protein Processing, Post-Translational; Pyridoxal Kinase; Pyridoxal Phosphate; Serratia marcescens

2021
Improvement of cadaverine production in whole cell system with baker's yeast for cofactor regeneration.
    Bioprocess and biosystems engineering, 2021, Volume: 44, Issue:4

    Topics: Adenosine Triphosphate; Agar; Biotechnology; Biotransformation; Cadaverine; Carboxy-Lyases; Escherichia coli; Fermentation; Industrial Microbiology; Lysine; Polymers; Pyridoxal; Pyridoxal Phosphate; Regeneration; Saccharomyces cerevisiae

2021
Snapshots along the catalytic path of KabA, a PLP-dependent aminotransferase required for kanosamine biosynthesis in Bacillus cereus UW85.
    Journal of structural biology, 2021, Volume: 213, Issue:2

    Topics: Bacillus cereus; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Coenzymes; Crystallography, X-Ray; Glucosamine; Glutarates; Lysine; Models, Molecular; Protein Conformation; Pyridoxal Phosphate; Transaminases

2021
The Nitrogen Atom of Vitamin B
    International journal of molecular sciences, 2022, May-06, Volume: 23, Issue:9

    Topics: Catalysis; Intramolecular Transferases; Lysine; Nitrogen; Pyridoxal Phosphate; Pyridoxine; Vitamin B 6; Vitamins

2022
A DFT study of the active role of the phosphate group of an internal aldimine in a transamination reaction.
    Organic & biomolecular chemistry, 2022, 07-06, Volume: 20, Issue:26

    Topics: Alanine; Amination; Lysine; Phosphates; Protons; Pyridoxal Phosphate

2022
MitoNEET's Reactivity of Lys55 toward Pyridoxal Phosphate Demonstrates its Activity as a Transaminase Enzyme.
    ACS chemical biology, 2022, 10-21, Volume: 17, Issue:10

    Topics: Cysteine; Glutamates; Histidine; Hydrogen; Iron; Iron-Sulfur Proteins; Ketoglutaric Acids; Lysine; Mitochondrial Proteins; Pyridoxal Phosphate; Sulfur; Transaminases

2022
Engineering synthetic microbial consortium for cadaverine biosynthesis from glycerol.
    Biotechnology letters, 2022, Volume: 44, Issue:12

    Topics: Cadaverine; Carbon; Corynebacterium glutamicum; Escherichia coli; Glycerol; Lysine; Microbial Consortia; Pyridoxal Phosphate

2022
Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
    Protein science : a publication of the Protein Society, 2022, Volume: 31, Issue:11

    Topics: Carrier Proteins; Escherichia coli; Escherichia coli Proteins; Homeostasis; Lysine; Phosphates; Protein Stability; Proteins; Pyridoxal Phosphate

2022
The Y430F mutant of Salmonella d-ornithine/d-lysine decarboxylase has altered stereospecificity and a putrescine allosteric activation site.
    Archives of biochemistry and biophysics, 2022, 11-30, Volume: 731

    Topics: Allosteric Regulation; Carboxy-Lyases; Kinetics; Lysine; Mutagenesis, Site-Directed; Ornithine; Ornithine Decarboxylase; Putrescine; Pyridoxal Phosphate; Salmonella

2022
A Comparative Study on the Effects of the Lysine Reagent Pyridoxal 5-Phosphate and Some Thiol Reagents in Opening the Tl
    International journal of molecular sciences, 2023, Jan-27, Volume: 24, Issue:3

    Topics: Animals; Calcium; Indicators and Reagents; Lysine; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Permeability; Pyridoxal Phosphate; Rats; Rats, Wistar; Sulfhydryl Reagents; Thallium

2023
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023