lysine has been researched along with piperidines in 71 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (42.25) | 18.7374 |
| 1990's | 7 (9.86) | 18.2507 |
| 2000's | 12 (16.90) | 29.6817 |
| 2010's | 16 (22.54) | 24.3611 |
| 2020's | 6 (8.45) | 2.80 |
| Authors | Studies |
|---|---|
| Fukumura, T; Hirasawa, T; Soda, K | 1 |
| Chang, YF; Myslinski, NR | 1 |
| Christensen, HN; De Cespedes, C; Handlogten, ME; Ronquist, G | 1 |
| Broquist, HP; Guengerich, FP | 1 |
| Leistner, E; Spenser, ID | 1 |
| Adams, E; Chang, YF | 1 |
| Kasé, Y; Kataoka, M; Miyata, T; Okano, Y | 1 |
| Dolezalova, H; Fairweather, R; Stepita-Klauco, M | 1 |
| Crawhall, JC; Watts, RW | 1 |
| Gross, D | 1 |
| Crowne, RS; Donninger, C; Grimble, RF; Whitehead, RG | 1 |
| Asatoor, AM; Crouchman, MR; Harrison, AR; Light, FW; Loughridge, LW; Milne, MD; Richards, AJ | 1 |
| Aplin, RT; Hope, DB; Horncastle, KC | 1 |
| Perham, RN; Richards, FM | 1 |
| Boulanger, P; Charlier, H; Osteux, R; Sacquet, E | 2 |
| Gupta, RN; Spenser, ID | 1 |
| Treacher, RJ | 1 |
| Severin, ES; Tomásek, V | 1 |
| Giacobini, E; Nomura, Y; Ortiz, J; Schmidt-Glenewinkel, T | 1 |
| Clarke, PH; Rahman, M | 1 |
| Chang, YF; Hernandez, MF; Myslinski, NR | 1 |
| Asada, Y; Misono, H; Sawada, S; Soda, K; Suzuki, T; Tanizawa, K | 1 |
| Ansorge, S; Kähne, T; Neubert, K | 1 |
| Ansorge, S; Bank, U; Bühling, F; Faust, J; Kähne, T; Kunt, D; Neubert, K; Reinhold, D | 1 |
| Finazzi-Agrò, A; Rescigno, A; Rinaldi, A; Rinaldi, AC; Sanjust, E | 1 |
| de La Fuente, JL; Liras, P; Martín, JF; Rumbero, A | 1 |
| Augustyns, K; Jung, G; Kraas, W | 1 |
| Ansorge, S; Faust, J; Kähne, T; Neubert, K | 1 |
| Fischer, LG; Hahnenkamp, K; Horstman, DJ; Kechner, NE; Rich, GF | 1 |
| Feldmeyer, D; Lübke, J; Radnikow, G | 1 |
| Barnett-Norris, J; Hurst, DP; Hyatt, SM; Lewis, D; Lynch, DL; Nie, J; Reggio, PH; Seltzman, HH; Song, ZH; Zhong, M | 1 |
| LOWY, PH | 1 |
| BUCKLEY, SD; MEISTER, A | 1 |
| HOSS, HG; SCHIEDT, U | 1 |
| HOESS, HG; SCHIEDT, U | 1 |
| BOULANGER, P; OSTEUX, R; SACQUET, E | 1 |
| LINDSTEDT, G; LINDSTEDT, S | 1 |
| Dineley, KT; Galvan, CD; Lam, TT; Schwartzkroin, PA; Swann, JW; Sweatt, JD; Wenzel, JH | 1 |
| NORDENSTROM, BE | 1 |
| Carmeliet, E; Carmeliet, P; Collen, D; Devriendt, K; Gewillig, M; Heidbüchel, H; Jongbloed, RJ; Mubagwa, K; Rossenbacker, T; Vereecke, J | 1 |
| Bravo, DT; Kolmakova, NG; Parsons, SM | 1 |
| Gravel, E; Hocquemiller, R; Poupon, E | 1 |
| Espinosa-Urgel, M; Fuhrer, T; Ramos, JL; Revelles, O; Sauer, U | 1 |
| Dettner, K; Lusebrink, I; Seifert, K | 1 |
| Luna, VM; Schoppa, NE | 1 |
| Andrew, R; Ellis, E; Pournamdari, M; Saadi, A; Walker, B; Watson, DG | 1 |
| Bao, Y; Jia, W; Qiu, Y; Su, M; Wang, X; Zhao, T | 1 |
| Kristie, TM; Liang, Y; Narayanan, A; Peng, H; Vogel, JL | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Ozawa, Y; Taguchi, K | 1 |
| Chen, X; Gong, ZC; Huang, Q; Liu, ZQ; Ren, HY; Sheng, FF; Wu, J; Xu, XJ; Yin, JY; Yu, M; Zhou, HH | 1 |
| Nikolov, PY; Yaylayan, VA | 1 |
| Ali, AB; Todorova, M | 1 |
| Ces, A; Kieffer, BL; Ouagazzal, AM; Prinssen, EP; Reiss, D; Walter, O; Wichmann, J | 1 |
| Dettner, K; Schierling, A; Schott, M; Seifert, K | 1 |
| Becker, A; Chandra, P; Dittrich, T; Klusmann, JH; Lippka, Y; Reinhardt, D; Selvakumar, D; Thakur, BK; Welte, K | 1 |
| Arrowsmith, CH; Barsyte-Lovejoy, D; Bedford, MT; Brown, PJ; Duan, S; Emili, A; Frye, SV; Gao, C; Greenblatt, JF; Guo, H; Herold, JM; Huang, XP; James, LI; Janzen, WP; Jin, J; Kireev, DB; Korboukh, VK; Krichevsky, L; MacNevin, CJ; Marcon, E; Norris, JL; Sagum, CA; Tempel, W; Zhong, N | 1 |
| Delatour, T; Dubois, M; Hammel, YA; Stadler, RH | 1 |
| Dölle, C; Skoge, RH; Ziegler, M | 1 |
| Bessaire, T; Delatour, T; Stadler, RH; Tarres, A | 1 |
| Proddutur, A; Santhakumar, V; Swietek, B; Yu, J | 1 |
| Gatto, B; Göttlich, R; Roesmann, R; Sosic, A; Zuravka, I | 1 |
| Bunsupa, S; Saito, K; Yamazaki, M | 1 |
| Brown, RE; McKenna, JT; Yang, C | 1 |
| Cilibrizzi, A; Ferraro, G; Infrasca, T; Marzo, T; Merlino, A; Messori, L; Vilar, R | 1 |
| Cui, Y; Feng, D; Liu, X; Zheng, M; Zhong, D | 1 |
| Channe Gowda, D; Kumara, HK; Pavan Kumar, H; Suhas, R | 1 |
| Akagawa, M; Itakura, M; Kitazawa, R; Lim, SY; Nagata, K; Shibata, T; Uchida, K; Yamaguchi, K | 1 |
| Campos, S; Evans, JP; Fournier, JCL; Patel, VK; Thomas, DA; Tomkinson, NCO; White, GV; Zappacosta, F | 1 |
| Chen, QX; Fan, XD; Jiang, JG; Liu, CJ; Zhu, W | 1 |
| Hamachi, I; Higashiguchi, K; Kawano, M; Matsuda, K; Murakawa, S; Tamura, T | 1 |
4 review(s) available for lysine and piperidines
| Article | Year |
|---|---|
Cystinuria.
Topics: Adolescent; Adult; Arginine; Biological Transport; Chemical Phenomena; Chemistry; Cystine; Cystinuria; Female; Heterozygote; Homocysteine; Homozygote; Humans; Jejunum; Kidney Tubules; Lysine; Male; Middle Aged; Ornithine; Penicillamine; Piperidines; Pyrrolidines | 1968 |
[Occurrence, structure and biosynthesis of natural piperidine compounds].
Topics: Alkaloids; Anti-Bacterial Agents; Carbonates; Cycloheximide; Deamination; Indoles; Lysine; Picolinic Acids; Piperidines; Plants; Plants, Medicinal; Protein Conformation; Structure-Activity Relationship; Terpenes | 1971 |
Lysine-derived Alkaloids: Overview and Update on Biosynthesis and Medicinal Applications with Emphasis on Quinolizidine Alkaloids.
Topics: Alkaloids; Indolizidines; Lycopodium; Lysine; Piperidines; Plants; Quinolizidines | 2017 |
Potential anticancer activities of securinine and its molecular targets.
Topics: Alkaloids; Azepines; Cell Line, Tumor; Heterocyclic Compounds, Bridged-Ring; Humans; Janus Kinases; Lactones; Leukemia; Lysine; Male; Phosphatidylinositols; Piperidines; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Tyrosine | 2022 |
1 trial(s) available for lysine and piperidines
| Article | Year |
|---|---|
KCNJ11 Lys23Glu and TCF7L2 rs290487(C/T) polymorphisms affect therapeutic efficacy of repaglinide in Chinese patients with type 2 diabetes.
Topics: Adult; Alleles; Amino Acid Substitution; Asian People; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Female; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Piperidines; Polymorphism, Genetic; Potassium Channels, Inwardly Rectifying; Risk Factors; TCF Transcription Factors; Transcription Factor 7-Like 2 Protein; Treatment Outcome | 2010 |
66 other study(ies) available for lysine and piperidines
| Article | Year |
|---|---|
Spectrophotometric determination of L-lysine with L-lysine: alpha-ketoglutarate epsilon-aminotransferase.
Topics: Flavobacterium; Ketoglutaric Acids; Lysine; Piperidines; Spectrophotometry; Transaminases | 1978 |
Effects of L-lysine and its metabolites on pentylenetetrazol-induced seizures.
Topics: 2-Aminoadipic Acid; Animals; Anticonvulsants; gamma-Aminobutyric Acid; Lysine; Male; Mice; Pentylenetetrazole; Pipecolic Acids; Piperidines; Seizures; Synaptic Transmission | 1985 |
Modified transport substrates as probes for intramembrane gradients.
Topics: Adenosine Triphosphate; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Radioisotopes; Carboxylic Acids; Carcinoma, Ehrlich Tumor; Cell Membrane; Choline; Dinitrophenols; Gramicidin; Kinetics; Lysine; Membrane Potentials; Methods; Mice; Models, Biological; Piperidines; Sodium; Time Factors | 1974 |
Biosynthesis of slaframine, (1S,6S,8aS)-1-acetoxy-6-aminooctahydroindolizine, a parasympathomimetic alkaloid of fungal origin. II. The origin of pipecolic acid.
Topics: Acetamides; Alkaloids; Amino Acid Isomerases; Carbon Radioisotopes; Chromatography, Ion Exchange; Hydroxylamines; Indolizines; Lysine; Mitosporic Fungi; NADP; Nitrogen Isotopes; Oxidoreductases; Parasympathomimetics; Pipecolic Acids; Piperidines; Pyridines; Stereoisomerism; Tritium | 1973 |
Biosynthesis of the piperidine nucleus. Incorporation of chirally labeled (1-3H)cadaverine.
Topics: Alkaloids; Amine Oxidase (Copper-Containing); Cadaverine; Isotope Labeling; Lysine; Models, Chemical; Piperidines; Polyamines; Stereoisomerism; Tritium | 1973 |
D-lysine catabolic pathway in Pseudomonas putida: interrelations with L-lysine catabolism.
Topics: Acetates; Adipates; Aldehydes; Alkanesulfonates; Amino Acid Isomerases; Carbon Radioisotopes; Carboxylic Acids; Cell-Free System; Chromatography, Ion Exchange; Enzyme Induction; Glutamates; Glutarates; Lysine; Mutagens; Mutation; Nitrosoguanidines; Oxidoreductases, N-Demethylating; Pipecolic Acids; Piperidines; Pseudomonas; Stereoisomerism; Valerates | 1974 |
Pipecolic acid in the dog brain.
Topics: Animals; Brain; Caudate Nucleus; Cerebellum; Chromatography; Chromatography, Paper; Diencephalon; Dogs; Female; Lysine; Male; Medulla Oblongata; Mesencephalon; Pipecolic Acids; Piperidines; Pons; Spinal Cord | 1973 |
The accumulation of piperidine in the central ganglia of dormant snails.
Topics: Animals; Brain; Cadaverine; Central Nervous System; Dose-Response Relationship, Drug; Ganglia; Hibernation; Lysine; Piperidines; Snails; Tritium | 1974 |
The isolation and identification of piperidine-2-carboxylic acid in the urine of protein malnourished rats.
Topics: Animals; Carboxylic Acids; Child; Child, Preschool; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Humans; Kwashiorkor; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Piperidines; Protein Deficiency; Rats | 1971 |
Intestinal absorption of oligopeptides in cystinuria.
Topics: Adult; Amino Acids; Animals; Arginine; Caseins; Cystinuria; Dipeptides; Glycine; Homozygote; Humans; In Vitro Techniques; Intestinal Absorption; Jejunum; Lysine; Piperidines; Pyrrolidines; Rats | 1971 |
The dimerization of delta-1-piperidine-2-carboxylic acid.
Topics: Amino Acid Oxidoreductases; Animals; Catalase; Chemical Phenomena; Chemistry, Physical; Lysine; Magnetic Resonance Spectroscopy; Manometry; Models, Chemical; Molecular Weight; Mollusca; Piperidines; Spectrophotometry; Spectrum Analysis | 1967 |
Reactivity and structural role of protein amino groups in tobacco mosaic virus.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chromatography, Paper; Electrophoresis; Fluoroacetates; Imides; Lysine; Microscopy, Electron; Piperidines; Tobacco Mosaic Virus; Trypsin; Ultracentrifugation; Viral Proteins | 1968 |
[Degradation of L-lysine in "germ-free" rats].
Topics: Amino Acids; Animals; Carbon Dioxide; Carbon Isotopes; Chromatography, Ion Exchange; Dicarboxylic Acids; Germ-Free Life; Lysine; Models, Biological; Pipecolic Acids; Piperidines; Rats; Time Factors; Urine | 1969 |
Biosynthesis of the piperidine nucleus. The mode of incorporation of lysine into pipecolic acid and into piperidine alkaloids.
Topics: Adipates; Aldehydes; Alkaloids; Amines; Aminocaproates; Animals; Carbon Isotopes; Keto Acids; Lysine; Neurospora; Pipecolic Acids; Piperidines; Plants; Plants, Medicinal; Rats; Tritium | 1969 |
Intestinal absorption of lysine in cystinuric dogs.
Topics: Amino Acids; Animals; Arginine; Cystine; Cystinuria; Dogs; Intestinal Absorption; Lysine; Piperidines; Pyrrolidines | 1965 |
Studies on the active site of trypsin. I. The reaction of trypsin with the specific inhibitor n-alpha-tosyl-l-lysyl-chloromethane and certain pseudosubstrates.
Topics: Amidines; Aminobutyrates; Butylamines; Chemical Phenomena; Chemistry; Hydrocarbons, Halogenated; Lysine; Piperidines; Spectrophotometry; Trypsin; Trypsin Inhibitors | 1965 |
Metabolism of cadaverine and pipecolic acid in brain and other organs of the mouse.
Topics: Animals; Brain; Cadaverine; Carbon Radioisotopes; Diamines; Intestine, Large; Kidney; Kinetics; Liver; Lysine; Mice; Myocardium; Organ Specificity; Pipecolic Acids; Piperidines | 1983 |
Genes and enzymes of lysine catabolism in Pseudomonas aeruginosa.
Topics: Cadaverine; Carboxy-Lyases; Chromosome Mapping; Genes, Regulator; Lysine; Mutation; Oxidoreductases; Piperidines; Pseudomonas aeruginosa; Transaminases; Transduction, Genetic | 1980 |
Enhancement of hexobarbital-induced sleep by lysine and its metabolites.
Topics: Age Factors; Animals; Body Weight; Drug Synergism; Hexobarbital; Lysine; Male; Pipecolic Acids; Piperidines; Rats; Sleep | 1981 |
Stereochemistry of meso-alpha,epsilon-diaminopimelate decarboxylase reaction: the first evidence for pyridoxal 5'-phosphate dependent decarboxylation with inversion of configuration.
Topics: Bacillus; Bacterial Proteins; Cadaverine; Carboxy-Lyases; Deuterium; Kinetics; Lysine; Piperidines; Pyridoxal Phosphate; Radioisotope Dilution Technique | 1981 |
Enzymatic activity of DPIV/CD26 is involved in PMA-induced hyperphosphorylation of p56lck.
Topics: Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lysine; Phosphorylation; Piperidines; Protease Inhibitors; Protein Kinase C; src-Family Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles | 1995 |
Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) specifically suppress proliferation and modulate cytokine production of strongly CD26 expressing U937 cells.
Topics: Blotting, Western; Cell Division; Cytokines; Dipeptidyl Peptidase 4; DNA; DNA Replication; Humans; Isoelectric Focusing; Lymphoma, Large B-Cell, Diffuse; Lysine; Piperidines; Thiazoles; Tumor Cells, Cultured | 1994 |
Photometric estimation of cadaverine oxidation by copper amine oxidase.
Topics: Amine Oxidase (Copper-Containing); Cadaverine; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Lysine; Ninhydrin; Oxidation-Reduction; Piperidines; Pyridines; Spectrophotometry | 1994 |
Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms alpha-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes.
Topics: 2-Aminoadipic Acid; Bacterial Proteins; Cephamycins; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Kinetics; L-Lysine 6-Transaminase; Lysine; Molecular Weight; NAD; Oxidoreductases Acting on CH-NH Group Donors; Picolinic Acids; Pipecolic Acids; Piperidines; Pyrroles; Quaternary Ammonium Compounds; Streptomyces; Substrate Specificity; Transaminases | 1997 |
Investigation on the stability of the Dde protecting group used in peptide synthesis: migration to an unprotected lysine.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Dimethylformamide; Drug Stability; Fluorenes; Lysine; Mass Spectrometry; Molecular Structure; Peptides; Piperidines | 1998 |
Early phosphorylation events induced by DPIV/CD26-specific inhibitors.
Topics: Calcium; CD3 Complex; Cyclic AMP; Dipeptidyl Peptidase 4; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lysine; Mitogens; Phosphorylation; Piperidines; Protease Inhibitors; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles; Tyrosine | 1998 |
Selective iNOS inhibition attenuates acetylcholine- and bradykinin-induced vasoconstriction in lipopolysaccharide-exposed rat lungs.
Topics: Acetylcholine; Animals; Bradykinin; Dexamethasone; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Lipopolysaccharides; Lung; Lysine; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Piperidines; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Vasoconstriction | 1999 |
Axonal projection, input and output synapses, and synaptic physiology of Cajal-Retzius cells in the developing rat neocortex.
Topics: Animals; Axons; Dendrites; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Lysine; Neocortex; Nerve Net; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2002 |
N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) interaction with LYS 3.28(192) is crucial for its inverse agonism at the cannabinoid CB1 receptor.
Topics: Binding Sites; Calcium; Cells, Cultured; Electrophysiology; Humans; Ligands; Lysine; Models, Molecular; Neurons; Piperidines; Protein Conformation; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Transfection | 2002 |
The conversion of lysine to pipecolic acid by Phaseolus vulgaris.
Topics: Biochemical Phenomena; Fabaceae; Lysine; Phaseolus; Pipecolic Acids; Piperidines | 1953 |
Pyridine nucleotide-dependent reduction of the alpha-keto acid analogue of lysine to L-pipecolic acid.
Topics: Keto Acids; Liver; Lysine; Nucleotides; Organic Chemicals; Pipecolic Acids; Piperidines; Pyridines | 1957 |
[Synthesis of pipecolic acid by closure of the lysine ring].
Topics: Lysine; Pipecolic Acids; Piperidines | 1957 |
[On the biogenesis of alkaloids. III. Lysine as the precursor to coniine].
Topics: Alkaloids; Humans; Lysine; Piperidines; Solanine | 1962 |
[Fate of L-pipecolic acid and delta1-piperidine-2-carboxylic acid in the "sterile" white rat].
Topics: Animals; Carboxylic Acids; Lysine; Pipecolic Acids; Piperidines; Proteins; Rats | 1963 |
[FORMATION OF CO2-14 FROM LABELED LYSINE, DELTA-1-PIPERIDINE-2-CARBOXYLIC ACID AND PIPECOLIC ACID IN THE "STERILE" RAT].
Topics: Amino Acids; Biochemical Phenomena; Carbon Isotopes; Carboxylic Acids; Lysine; Metabolism; Pipecolic Acids; Piperidines; Radiometry; Rats; Research | 1964 |
On the formation of 5-hydroxypipecolic acid from 5-hydroxy-DL-lysine.
Topics: Hydroxylysine; Lysine; Pipecolic Acids; Piperidines | 1959 |
Postsynaptic contributions to hippocampal network hyperexcitability induced by chronic activity blockade in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Animals, Newborn; Axons; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Immunoblotting; Immunohistochemistry; In Vitro Techniques; Lysine; Membrane Potentials; Microscopy, Confocal; Microscopy, Electron; Nerve Net; Patch-Clamp Techniques; Piperidines; Pyramidal Cells; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptophysin; Tetrodotoxin; Time Factors | 2003 |
Effect of cadaverine and lysine on the urinary excretion of piperidine in rabbits.
Topics: Animals; Cadaverine; Lysine; Piperidines; Rabbits | 1951 |
Novel mutation in the Per-Arnt-Sim domain of KCNH2 causes a malignant form of long-QT syndrome.
Topics: Adult; Blotting, Western; Cell Line; Death, Sudden, Cardiac; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Glutamic Acid; Humans; Kidney; Long QT Syndrome; Lysine; Male; Microscopy, Confocal; Middle Aged; Mutation, Missense; Patch-Clamp Techniques; Pedigree; Peptides; Phenotype; Piperidines; Potassium Channels, Voltage-Gated; Protein Structure, Tertiary; Proteins; Pyridines | 2005 |
Mutational and pH analysis of ionic residues in transmembrane domains of vesicular acetylcholine transporter.
Topics: Acetylcholine; Animals; Aspartic Acid; Binding Sites; Biological Transport; Blotting, Western; Cell Line; Cell Membrane; Fluorescent Antibody Technique, Direct; Histidine; Hydrogen-Ion Concentration; Lysine; Membrane Transport Proteins; Microscopy, Confocal; Mutagenesis, Site-Directed; Piperidines; Protein Structure, Tertiary; Rats; Static Electricity; Vesicular Acetylcholine Transport Proteins | 2005 |
Biomimetic one-step access to nitraramine from simple C5 units. Revision of the previously reported structure of epinitraramine to nitraramine.
Topics: Alkaloids; Catalysis; Lysine; Molecular Mimicry; Nuclear Magnetic Resonance, Biomolecular; Piperidines; Stereoisomerism | 2005 |
Multiple and interconnected pathways for L-lysine catabolism in Pseudomonas putida KT2440.
Topics: 2-Aminoadipic Acid; Amino Acid Isomerases; Bacterial Proteins; Carbon; Carbon Radioisotopes; DNA Transposable Elements; Enzymes; Gas Chromatography-Mass Spectrometry; Genes, Bacterial; Glutarates; Lysine; Mutagenesis, Insertional; Mutation; Nitrogen; Pipecolic Acids; Piperidines; Pseudomonas putida; Valerates | 2005 |
Biosynthesis of stenusine.
Topics: Alkaloids; Animals; Coleoptera; Drosophila melanogaster; Gas Chromatography-Mass Spectrometry; Isoleucine; Lysine; Molecular Structure; Piperidines | 2008 |
GABAergic circuits control input-spike coupling in the piriform cortex.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cerebral Cortex; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Lysine; Models, Neurological; Nerve Net; Neurons; Olfactory Pathways; Patch-Clamp Techniques; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Triazines | 2008 |
Development of a derivatisation method for the analysis of aldehyde modified amino acid residues in proteins by Fourier transform mass spectrometry.
Topics: Aldehydes; Amino Acids; Animals; Blood Proteins; Chromatography, Liquid; Fourier Analysis; Histidine; Humans; Lysine; Mass Spectrometry; Piperidines; Pyridinium Compounds; Schiff Bases; Serum Albumin, Bovine | 2009 |
Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers.
Topics: Carbamates; Diabetes Mellitus, Type 2; Gas Chromatography-Mass Spectrometry; Humans; Hypoglycemic Agents; Lactic Acid; Lysine; Metabolomics; Metformin; Piperidines; Rosiglitazone; Thiazolidinediones; Uric Acid; Valine | 2009 |
Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency.
Topics: Animals; Cell Line, Transformed; Chromatin Immunoprecipitation; DNA Replication; Enzyme Activation; Ganglia; Gene Expression Regulation, Viral; Green Fluorescent Proteins; Herpesvirus 1, Human; Herpesvirus 3, Human; Histone Demethylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Host Cell Factor C1; Humans; Lysine; Mice; Monoamine Oxidase Inhibitors; Mutation; Neurons; Pargyline; Phencyclidine; Piperidines; Promoter Regions, Genetic; Reaction Time; RNA, Small Interfering; Simplexvirus; Thiophenes; Time Factors; Transfection; Virus Replication | 2009 |
Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction.
Topics: Animals; Aspartic Acid Endopeptidases; Benzofurans; Blood Glucose; Body Weight; Coronary Vessels; Diabetes Mellitus, Experimental; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glycopeptides; Heart; Lipids; Lysine; Male; Metalloendopeptidases; Myocardium; Oligopeptides; Organ Size; Organophosphonates; Peptides, Cyclic; Perfusion; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Thiorphan; Vasoconstriction | 2010 |
Formation of Pent-4-en-1-amine, the counterpart of acrylamide from lysine and its conversion into piperidine in lysine/glucose reaction mixtures.
Topics: Acrylamide; Chemical Phenomena; Glucose; Lysine; Piperidines | 2010 |
Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1.
Topics: Animals; Animals, Newborn; Arachidonic Acids; CA1 Region, Hippocampal; Cannabinoid Receptor Modulators; Chelating Agents; Cholecystokinin; Dendrites; Egtazic Acid; Endocannabinoids; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lysine; Male; Neural Inhibition; Neural Pathways; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Synapses | 2010 |
Activation of nociceptin/orphanin FQ peptide receptors disrupts visual but not auditory sensorimotor gating in BALB/cByJ mice: comparison to dopamine receptor agonists.
Topics: Acoustic Stimulation; Animals; Benzimidazoles; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Imidazoles; Lysine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Narcotic Antagonists; Nociceptin Receptor; Photic Stimulation; Piperidines; Receptors, Dopamine; Receptors, Opioid; Reflex, Startle; Sensory Gating; Spiro Compounds | 2012 |
Biosynthesis of the defensive alkaloid (Z)-3-(2-methyl-1-butenyl)pyridine in Stenus similis beetles.
Topics: Alkaloids; Animals; Coleoptera; Gas Chromatography-Mass Spectrometry; Germany; Isoleucine; Lysine; Molecular Structure; Piperidines; Pyridines; Stereoisomerism | 2011 |
Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cells.
Topics: Acetylation; Acrylamides; Apoptosis; Cell Cycle; Cytokines; Enzyme Inhibitors; Gene Knockdown Techniques; HEK293 Cells; Humans; Lysine; Metabolic Networks and Pathways; Neoplasms; Nicotinamide Phosphoribosyltransferase; Piperidines; Simian virus 40; Sirtuin 1; Tumor Suppressor Protein p53 | 2012 |
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.
Topics: Benzamides; Binding, Competitive; Crystallography, X-Ray; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Lysine; Models, Molecular; Molecular Probes; Molecular Structure; Piperidines; Protein Structure, Tertiary; Repressor Proteins; Structure-Activity Relationship; Tumor Suppressor Proteins | 2013 |
N,N-dimethylpiperidinium (mepiquat): Part 1. Formation in model systems and relevance to roasted food products.
Topics: Alkaloids; Food Analysis; Hot Temperature; Lysine; Piperidines; Plant Growth Regulators | 2014 |
Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels.
Topics: Acetylation; Acrylamides; Enzyme Inhibitors; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lysine; NAD; Phenanthrenes; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Sirtuin 2; Tubulin | 2014 |
Role of choline and glycine betaine in the formation of N,N-dimethylpiperidinium (mepiquat) under Maillard reaction conditions.
Topics: Alkaloids; Betaine; Carbon Radioisotopes; Choline; Chromatography, High Pressure Liquid; Deuterium; Hot Temperature; Kinetics; Lysine; Maillard Reaction; Methylation; Models, Chemical; Molecular Structure; Molecular Weight; Piperidines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Dentate total molecular layer interneurons mediate cannabinoid-sensitive inhibition.
Topics: Action Potentials; Animals; Biophysics; Cannabinoid Receptor Modulators; Cannabinoids; Cholecystokinin; Dentate Gyrus; Electric Stimulation; In Vitro Techniques; Interneurons; Lysine; Male; Neural Inhibition; Parvalbumins; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Statistics, Nonparametric; Synapses | 2015 |
Bis-3-chloropiperidines containing bridging lysine linkers: Influence of side chain structure on DNA alkylating activity.
Topics: Alkylation; DNA; DNA Cleavage; Lysine; Molecular Structure; Piperidines; Plasmids | 2015 |
Intrinsic membrane properties and cholinergic modulation of mouse basal forebrain glutamatergic neurons in vitro.
Topics: Action Potentials; Animals; Animals, Genetically Modified; Animals, Newborn; Basal Forebrain; Benzamides; Calcium Channel Blockers; Carbachol; Cholinergic Agents; Electric Stimulation; Glutamates; Luminescent Proteins; Lysine; Mice; Neurons; Patch-Clamp Techniques; Piperidines; Pyrimidines; Red Fluorescent Protein; Sodium Channel Blockers; Tetrodotoxin; Vesicular Glutamate Transport Protein 2 | 2017 |
A case of extensive protein platination: the reaction of lysozyme with a Pt(ii)-terpyridine complex.
Topics: Crystallography, X-Ray; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Ligands; Lysine; Molecular Conformation; Muramidase; Organoplatinum Compounds; Piperidines; Platinum; Protein Binding; Pyridines; Spectrometry, Mass, Electrospray Ionization; Succinic Acid; Water | 2018 |
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins.
Topics: Acrylamides; Adenine; Aminoquinolines; Aniline Compounds; Animals; Binding Sites; Dogs; Haplorhini; Humans; Indoles; Lysine; Mice; Molecular Docking Simulation; Molecular Structure; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Quinolines; Rabbits; Rats; Serum Albumin, Human | 2020 |
Multitarget-directed therapeutics: (Urea/thiourea)
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Heterocyclic Compounds; Humans; Isoxazoles; Lysine; Molecular Docking Simulation; Piperazines; Piperidines; Structure-Activity Relationship; Thiourea; Urea | 2021 |
Oxidative deamination of lysine residues by polyphenols generates an equilibrium of aldehyde and 2-piperidinol products.
Topics: Aldehydes; Cyclization; Deamination; Lysine; Oxidation-Reduction; Piperidines; Polyphenols; Protein-Lysine 6-Oxidase | 2021 |
Acetylation of the Catalytic Lysine Inhibits Kinase Activity in PI3Kδ.
Topics: Acetylation; Acrylamides; Adenine; Afatinib; Amino Acid Sequence; Aniline Compounds; Catalysis; Catalytic Domain; Class I Phosphatidylinositol 3-Kinases; Humans; Lysine; Mass Spectrometry; Molecular Docking Simulation; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Binding; Protein Conformation; Substrate Specificity | 2021 |
Lysine-Reactive
Topics: Agammaglobulinaemia Tyrosine Kinase; Cysteine; Lysine; Piperidines; Protein Kinase Inhibitors; Sulfanilamide; Sulfonamides | 2023 |