lysine has been researched along with pipecolic acid in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (24.53) | 18.7374 |
| 1990's | 9 (16.98) | 18.2507 |
| 2000's | 10 (18.87) | 29.6817 |
| 2010's | 17 (32.08) | 24.3611 |
| 2020's | 4 (7.55) | 2.80 |
| Authors | Studies |
|---|---|
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Broquist, HP | 1 |
| Chang, YF; Chen, JS; Hargest, V | 1 |
| Chang, YF; Myslinski, NR | 1 |
| Dancis, J; Hutzler, J | 1 |
| Giacobini, E; Nomura, Y; Ortiz, J; Schmidt-Glenewinkel, T | 1 |
| Beemer, FA; Duran, M; Janssen, B; Wadman, SK; Wendel, U | 1 |
| Giacobini, E; Nishio, H | 1 |
| Bhattacharjee, JK; Kinzel, JJ | 1 |
| Chang, YF; Charles, AK | 1 |
| Cheng, YR; Demain, AL; Fang, A | 1 |
| Bellet, H; Denis, S; Jakobs, C; Mion, H; Vallat, C; Wanders, RJ | 1 |
| Perry, D; Sim, KL | 1 |
| de La Fuente, JL; Liras, P; Martín, JF; Rumbero, A | 1 |
| Crook, JM; Eysel, UT; Kisvárday, ZF | 1 |
| Fujita, T; Hada, T; Higashino, K | 1 |
| Hussain-Yusuf, H; Nasser, ME; Onodera, R; Sato, H | 1 |
| de Kromme, I; IJlst, L; Oostheim, W; Wanders, RJ | 1 |
| Bañuelos, O; Casqueiro, J; Lopez, P; Martin de Valmaseda, E; Martin, JF; Naranjo, L; Riaño, J | 1 |
| Agematu, H; Fujii, T; Mukaihara, M; Tsunekawa, H | 1 |
| Agematu, H; Aritoku, Y; Fujii, T; Tsunekawa, H | 1 |
| Christensen, E; de Koning, TJ; Dorland, L; Hoffmann, GF; Knerr, I; Müller, P; Rascher, W; Trautmann, U; Trefz, FK; Wündisch, GF; Zschocke, J | 1 |
| LOWY, PH | 1 |
| MILLER, LL; ROTHSTEIN, M | 1 |
| BUCKLEY, SD; MEISTER, A | 1 |
| HOSS, HG; SCHIEDT, U | 1 |
| BOULANGER, P; OSTEUX, R; SACQUET, E | 1 |
| BOULANGER, P; CHARLIER, H; OSTEUX, R; SACQUET, E | 1 |
| Espinosa-Urgel, M; Fuhrer, T; Ramos, JL; Revelles, O; Sauer, U | 1 |
| He, M | 1 |
| Barbirato, F; Tsotsou, GE | 1 |
| Gallagher, RC; Hyland, K; Jakobs, C; Mercimek-Mahmutoglu, S; Plecko, B; Rosenberg, EH; Salomons, GS; Scharer, G; Stockler-Ipsiroglu, S; Struys, EA; Van Hove, JL; Waters, PJ | 1 |
| Jakobs, C; Struys, EA | 1 |
| Bland, RJ; Simpson, HV; Umair, S | 1 |
| Bok, LA; Cheng, B; Collet, JP; Connolly, M; Coughlin, CR; Das, AM; Gospe, SM; Hartmann, H; Jaggumantri, S; Jakobs, C; Mercimek-Mahmutoglu, S; Meyer, U; Plecko, BR; Sinclair, G; Stockler, S; Struys, E; van der Lee, JH; Van Hove, J; van Karnebeek, CD | 1 |
| Coelho, JG; Dalazen, GR; Dutra-Filho, CS; Freitas, R; Jacques, CE; Mazzola, PN; Terra, M | 1 |
| Hoffmann, GF; Kölker, S; Mohr, H; Okun, JG; Opp, S; Posset, R; Sauer, SW; Struys, EA; Völkl, A | 1 |
| Fujimura, S; Kadowaki, M; Kobayashi, H; Kubota, M; Shibata, M; Watanabe, G | 1 |
| China, H; Dekishima, Y; Kawabata, H; Mihara, H; Miyake, R; Saito, S; Tani, Y; Yukami, R | 1 |
| Ludewig, U; Yang, H | 1 |
| Chou, HT; Lu, CD; Madhuri Indurthi, S | 1 |
| Botto, LD; De Biase, I; Liu, A; Longo, N; Pasquali, M; Thomas, A; Viau, K; Yuzyuk, T | 1 |
| Pérez-García, F; Peters-Wendisch, P; Wendisch, VF | 1 |
| García-Villoria, J; Girós, M; Ribes, A; Ruiz, A; Torres, MA; Tort, F; Ugarteburu, O | 1 |
| Chen, P; Cheng, J; Song, A; Wang, D; Wang, Q | 1 |
| Chen, W; Cheng, J; Huang, Y; Mi, L; Wang, D; Wang, Q | 1 |
| Crowther, LM; Mathis, D; Plecko, B; Poms, M | 1 |
| Gong, P; Jiang, S; Jiang, Y; Li, H; Wang, J; Wu, M; Wu, Y; Xue, J; Yang, W; Yang, Z; Yuzyuk, T; Zhang, Y | 1 |
| Alonso-Gómez, A; Clish, CB; Corella, D; Dennis, C; Estruch, R; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hu, FB; Lapetra, J; Li, J; Liang, L; Martínez-González, MA; Pierce, KA; Razquin, C; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Huetos, A; Salas-Salvadó, J; Serra-Majem, L; Toledo, E | 1 |
| Bhatia, SK; Choi, TR; Gurav, R; Han, YH; Kim, HJ; Lee, HS; Lee, SM; Park, JY; Park, SL; Park, YL; Song, HS; Yang, YH | 1 |
| Benoist, JF; Mention, K; Minet, P; Miret, A; Remerand, G; Sarret, C | 1 |
| Cheng, J; Lu, Y; Luo, Z; Wang, B; Wang, W; Yan, L; Zhang, J; Zhang, S | 1 |
| Becker, J; Kohlstedt, M; Lamber, J; Pauli, S; Weiland, F; Wittmann, C | 1 |
3 review(s) available for lysine and pipecolic acid
| Article | Year |
|---|---|
Lysine-pipecolic acid metabolic relationships in microbes and mammals.
Topics: Animals; Fungi; Humans; Lysine; Mammals; Pipecolic Acids; Pseudomonas; Zellweger Syndrome | 1991 |
Pipecolic acid in microbes: biosynthetic routes and enzymes.
Topics: 2-Aminoadipic Acid; Bacteria; Lysine; Pipecolic Acids | 2006 |
Expanding lysine industry: industrial biomanufacturing of lysine and its derivatives.
Topics: Amino Acids; Amino Acids, Neutral; Aminocaproic Acid; Biocompatible Materials; Cadaverine; Caprolactam; Chemistry, Pharmaceutical; Corynebacterium glutamicum; Escherichia coli; Fermentation; Green Chemistry Technology; Industrial Microbiology; Lactams; Lysine; Pipecolic Acids; Piperidones; Polymers | 2018 |
50 other study(ies) available for lysine and pipecolic acid
| Article | Year |
|---|---|
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Modulation of benzodiazepine by lysine and pipecolic acid on pentylenetetrazol-induced seizures.
Topics: Animals; Biological Transport; Brain; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; Lysine; Male; Mice; Pentylenetetrazole; Pipecolic Acids; Receptors, GABA-A; Seizures | 1988 |
Effects of L-lysine and its metabolites on pentylenetetrazol-induced seizures.
Topics: 2-Aminoadipic Acid; Animals; Anticonvulsants; gamma-Aminobutyric Acid; Lysine; Male; Mice; Pentylenetetrazole; Pipecolic Acids; Piperidines; Seizures; Synaptic Transmission | 1985 |
The significance of hyperpipecolatemia in Zellweger syndrome.
Topics: Abnormalities, Multiple; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Humans; Infant; Infant, Newborn; Kidney Diseases; Liver Diseases; Lysine; Pipecolic Acids; Syndrome | 1986 |
Metabolism of cadaverine and pipecolic acid in brain and other organs of the mouse.
Topics: Animals; Brain; Cadaverine; Carbon Radioisotopes; Diamines; Intestine, Large; Kidney; Kinetics; Liver; Lysine; Mice; Myocardium; Organ Specificity; Pipecolic Acids; Piperidines | 1983 |
A patient with alpha-ketoadipic and alpha-aminoadipic aciduria.
Topics: 2-Aminoadipic Acid; Adipates; Amino Acid Metabolism, Inborn Errors; Amino Acids, Dicarboxylic; Child; Dietary Proteins; Fibroblasts; Humans; Lysine; Male; Pipecolic Acids; Tryptophan | 1984 |
Brain uptake of pipecolic acid, amino acids, amines following intracarotid injection in the mouse.
Topics: Amines; Amino Acids; Animals; Biological Transport; Brain; Carbon Radioisotopes; Kinetics; Lysine; Male; Mice; Mice, Inbred C57BL; Pipecolic Acids; Proline; Rats; Tritium | 1981 |
Lysine biosynthesis in Rhodotorula glutinis: properties of pipecolic acid oxidase.
Topics: Hot Temperature; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lysine; Mitosporic Fungi; Molecular Weight; Oxidoreductases Acting on CH-NH Group Donors; Pipecolic Acids; Rhodotorula | 1982 |
Uptake and metabolism of delta 1-piperidine-2-carboxylic acid by synaptosomes from rat cerebral cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamic Acid; Kinetics; Lysine; Male; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Synaptosomes | 1995 |
Effect of amino acids on rapamycin biosynthesis by Streptomyces hygroscopicus.
Topics: Amino Acids; Antifungal Agents; Culture Media; Lysine; Methionine; Phenylalanine; Pipecolic Acids; Polyenes; Quaternary Ammonium Compounds; Sirolimus; Streptomyces | 1995 |
Major hyperpipecolataemia in a normal adult.
Topics: Adult; Humans; Lysine; Male; Peroxisomal Disorders; Pipecolic Acids; Stereoisomerism | 1996 |
Analysis of swainsonine and its early metabolic precursors in cultures of Metarhizium anisopliae.
Topics: 2-Aminoadipic Acid; Chromatography, High Pressure Liquid; Lysine; Mitosporic Fungi; Pipecolic Acids; Swainsonine | 1997 |
Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms alpha-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes.
Topics: 2-Aminoadipic Acid; Bacterial Proteins; Cephamycins; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Kinetics; L-Lysine 6-Transaminase; Lysine; Molecular Weight; NAD; Oxidoreductases Acting on CH-NH Group Donors; Picolinic Acids; Pipecolic Acids; Piperidines; Pyrroles; Quaternary Ammonium Compounds; Streptomyces; Substrate Specificity; Transaminases | 1997 |
Evidence for a contribution of lateral inhibition to orientation tuning and direction selectivity in cat visual cortex: reversible inactivation of functionally characterized sites combined with neuroanatomical tracing techniques.
Topics: Animals; Cats; Functional Laterality; gamma-Aminobutyric Acid; Iontophoresis; Lysine; Neural Inhibition; Neurons; Nipecotic Acids; Orientation; Proline; Synaptic Transmission; Visual Cortex | 1998 |
Origin of D- and L-pipecolic acid in human physiological fluids: a study of the catabolic mechanism to pipecolic acid using the lysine loading test.
Topics: Chromatography, High Pressure Liquid; Diet; Glycine max; Humans; Lysine; Pipecolic Acids; Plants, Edible; Spectrophotometry, Ultraviolet; Stereoisomerism | 1999 |
Simple method for the simultaneous analysis of pipecolic acid and lysine by high-performance liquid chromatography and its application to rumen liquor and plasma of ruminants.
Topics: Animals; Body Fluids; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Female; Goats; Hydrogen-Ion Concentration; Lysine; Male; Pipecolic Acids; Quality Control; Reproducibility of Results; Rumen; Sensitivity and Specificity; Spectrometry, Fluorescence | 1999 |
Molecular cloning and expression of human L-pipecolate oxidase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cloning, Molecular; Escherichia coli; Flavoproteins; Haplorhini; Humans; Lysine; Molecular Sequence Data; Oxidoreductases Acting on CH-NH Group Donors; Pipecolic Acids; Polymerase Chain Reaction; Protein Folding; Recombinant Proteins; Sarcosine Oxidase | 2000 |
Conversion of pipecolic acid into lysine in Penicillium chrysogenum requires pipecolate oxidase and saccharopine reductase: characterization of the lys7 gene encoding saccharopine reductase.
Topics: Amino Acid Sequence; Cloning, Molecular; Genes, Fungal; Genetic Complementation Test; Lysine; Molecular Sequence Data; Mutation; Open Reading Frames; Oxidoreductases Acting on CH-NH Group Donors; Penicillium chrysogenum; Pipecolic Acids; Plasmids; Saccharopine Dehydrogenases; Sequence Homology, Amino Acid; Transformation, Bacterial | 2001 |
Biotransformation of L-lysine to L-pipecolic acid catalyzed by L-lysine 6-aminotransferase and pyrroline-5-carboxylate reductase.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fermentation; Genetic Complementation Test; L-Lysine 6-Transaminase; Lysine; Mass Spectrometry; Oxidation-Reduction; Pipecolic Acids; Plasmids; Pyrroline Carboxylate Reductases; Recombinant Proteins; Transaminases | 2002 |
Increase in the rate of L-pipecolic acid production using lat-expressing Escherichia coli by lysP and yeiE amplification.
Topics: Amino Acid Transport Systems, Basic; Biological Transport; Escherichia coli; Escherichia coli Proteins; Gene Amplification; Gene Expression Regulation, Bacterial; Genes, Bacterial; L-Lysine 6-Transaminase; Lysine; Pipecolic Acids; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Ribosomal, 16S; Transaminases | 2002 |
Glutaric aciduria type III: a distinctive non-disease?
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chromosome Deletion; Diarrhea; Fasting; Female; Glutarates; Humans; Liver; Lysine; Male; Pipecolic Acids; Riboflavin | 2002 |
The conversion of lysine to pipecolic acid by Phaseolus vulgaris.
Topics: Biochemical Phenomena; Fabaceae; Lysine; Phaseolus; Pipecolic Acids; Piperidines | 1953 |
The conversion of lysine to pipecolic acid in the rat.
Topics: Animals; Lysine; Pipecolic Acids; Pyridines; Rats | 1954 |
Pyridine nucleotide-dependent reduction of the alpha-keto acid analogue of lysine to L-pipecolic acid.
Topics: Keto Acids; Liver; Lysine; Nucleotides; Organic Chemicals; Pipecolic Acids; Piperidines; Pyridines | 1957 |
[Synthesis of pipecolic acid by closure of the lysine ring].
Topics: Lysine; Pipecolic Acids; Piperidines | 1957 |
[Fate of L-pipecolic acid and delta1-piperidine-2-carboxylic acid in the "sterile" white rat].
Topics: Animals; Carboxylic Acids; Lysine; Pipecolic Acids; Piperidines; Proteins; Rats | 1963 |
[FORMATION OF CO2-14 FROM LABELED LYSINE, DELTA-1-PIPERIDINE-2-CARBOXYLIC ACID AND PIPECOLIC ACID IN THE "STERILE" RAT].
Topics: Amino Acids; Biochemical Phenomena; Carbon Isotopes; Carboxylic Acids; Lysine; Metabolism; Pipecolic Acids; Piperidines; Radiometry; Rats; Research | 1964 |
Multiple and interconnected pathways for L-lysine catabolism in Pseudomonas putida KT2440.
Topics: 2-Aminoadipic Acid; Amino Acid Isomerases; Bacterial Proteins; Carbon; Carbon Radioisotopes; DNA Transposable Elements; Enzymes; Gas Chromatography-Mass Spectrometry; Genes, Bacterial; Glutarates; Lysine; Mutagenesis, Insertional; Mutation; Nitrogen; Pipecolic Acids; Piperidines; Pseudomonas putida; Valerates | 2005 |
Biochemical characterisation of recombinant Streptomyces pristinaespiralis L-lysine cyclodeaminase.
Topics: Ammonia-Lyases; Glycerol; Hydrogen-Ion Concentration; Iron; Kinetics; Lysine; Pipecolic Acids; Recombinant Proteins; Streptomycetaceae; Substrate Specificity; Temperature | 2007 |
Folinic acid-responsive seizures are identical to pyridoxine-dependent epilepsy.
Topics: Aldehyde Dehydrogenase; Biogenic Monoamines; DNA Mutational Analysis; Humans; Infant; Leucovorin; Linear Models; Lysine; Male; Mutation; Pipecolic Acids; Pyridoxine; Seizures; Tandem Mass Spectrometry; Vitamin B Complex | 2009 |
Metabolism of lysine in alpha-aminoadipic semialdehyde dehydrogenase-deficient fibroblasts: evidence for an alternative pathway of pipecolic acid formation.
Topics: Aldehyde Dehydrogenase; Cell Line; Fibroblasts; Humans; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Neoplasm Proteins; Picolinic Acids; Pipecolic Acids; Pyrroles | 2010 |
Lysine catabolism in Haemonchus contortus and Teladorsagia circumcincta.
Topics: Animals; Cadaverine; Haemonchus; Hydrogen-Ion Concentration; Kinetics; Larva; Lysine; Mixed Function Oxygenases; Oxidoreductases Acting on CH-NH Group Donors; Pipecolic Acids; Saccharopine Dehydrogenases; Trichostrongyloidea | 2012 |
Lysine restricted diet for pyridoxine-dependent epilepsy: first evidence and future trials.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Child; Child, Preschool; Cognition; Diet; Epilepsy; Female; Humans; Infant; Longitudinal Studies; Lysine; Male; Pipecolic Acids; Pyridoxine | 2012 |
Pipecolic acid induces oxidative stress in vitro in cerebral cortex of young rats and the protective role of lipoic acid.
Topics: Animals; Antioxidants; Catalase; Cerebral Cortex; Female; Glutathione; In Vitro Techniques; Lipid Peroxidation; Lysine; Male; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Oxidoreductases; Pipecolic Acids; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Thioctic Acid | 2014 |
Understanding cerebral L-lysine metabolism: the role of L-pipecolate metabolism in Gcdh-deficient mice as a model for glutaric aciduria type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; Deamination; Disease Models, Animal; Genetic Predisposition to Disease; Glutaryl-CoA Dehydrogenase; Liver; Lysine; Mice, Knockout; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Peroxisomes; Phenotype; Pipecolic Acids | 2015 |
Regulation of free glutamate content in meat by dietary lysine in broilers.
Topics: 2-Aminoadipic Acid; Animal Feed; Animals; Chickens; Dietary Supplements; Female; Food Quality; Glutamic Acid; Liver; Lysine; Meat; Muscles; Pipecolic Acids; RNA, Messenger; Saccharopine Dehydrogenases | 2015 |
Functional expression of L-lysine α-oxidase from Scomber japonicus in Escherichia coli for one-pot synthesis of L-pipecolic acid from DL-lysine.
Topics: Amino Acid Oxidoreductases; Animals; Enzyme Stability; Escherichia coli; Fermentation; Fish Proteins; Fishes; Lysine; Metabolic Engineering; Pipecolic Acids; Stereoisomerism; Substrate Specificity | 2015 |
Lysine catabolism, amino acid transport, and systemic acquired resistance: what is the link?.
Topics: Amino Acid Transport Systems, Basic; Amino Acids; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Biological Transport; Disease Resistance; Gene Expression Regulation, Plant; Genes, Plant; Homeostasis; Lysine; Pipecolic Acids; Plant Diseases; Pseudomonas syringae; Salicylic Acid; Signal Transduction | 2014 |
Molecular characterization of lysR-lysXE, gcdR-gcdHG and amaR-amaAB operons for lysine export and catabolism: a comprehensive lysine catabolic network in Pseudomonas aeruginosa PAO1.
Topics: 2-Aminoadipic Acid; Bacterial Proteins; Base Sequence; Biological Transport; Carboxy-Lyases; Coenzyme A-Transferases; DNA-Binding Proteins; DNA, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genome, Bacterial; Glutarates; Glutaryl-CoA Dehydrogenase; Lysine; Pipecolic Acids; Promoter Regions, Genetic; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Deletion; Transaminases; Transcription Factors; Transcriptional Activation | 2016 |
Effect of dietary lysine restriction and arginine supplementation in two patients with pyridoxine-dependent epilepsy.
Topics: Arginine; Biomarkers; Child, Preschool; Dietary Supplements; Epilepsy; Female; Humans; Infant; Lysine; Male; Pipecolic Acids; Retrospective Studies; Saccharopine Dehydrogenases; Treatment Outcome | 2016 |
Engineering Corynebacterium glutamicum for fast production of L-lysine and L-pipecolic acid.
Topics: Bacillus subtilis; Corynebacterium glutamicum; Gene Deletion; Gene Expression; Lysine; Metabolic Engineering; Metabolic Networks and Pathways; Pipecolic Acids; Recombinant Proteins; Rhodobacteraceae; Streptomyces coelicolor | 2016 |
Lysine Restriction and Pyridoxal Phosphate Administration in a NADK2 Patient.
Topics: Child; Diet; Epilepsies, Myoclonic; Female; Homozygote; Humans; Hyperlysinemias; Lactic Acid; Lysine; Mitochondrial Diseases; Mitochondrial Proteins; Mutation; Nervous System Malformations; Phosphotransferases (Alcohol Group Acceptor); Pipecolic Acids; Pyridoxal Phosphate; RNA, Messenger; Vitamin B Complex | 2016 |
An economically and environmentally acceptable synthesis of chiral drug intermediate L-pipecolic acid from biomass-derived lysine via artificially engineered microbes.
Topics: Amino Acid Oxidoreductases; Bacillus subtilis; Biomass; Chemistry, Pharmaceutical; Escherichia coli; Fermentation; Glucose 1-Dehydrogenase; Green Chemistry Technology; Industrial Microbiology; Lysine; Metabolic Engineering; Pipecolic Acids; Plasmids; Pseudomonas putida; Stereoisomerism | 2018 |
New insights into human lysine degradation pathways with relevance to pyridoxine-dependent epilepsy due to antiquitin deficiency.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Epilepsy; Humans; Lysine; Metabolic Networks and Pathways; Pipecolic Acids; Vitamin B 6 | 2019 |
Simultaneous quantification of alpha-aminoadipic semialdehyde, piperideine-6-carboxylate, pipecolic acid and alpha-aminoadipic acid in pyridoxine-dependent epilepsy.
Topics: 2-Aminoadipic Acid; Biomarkers; Child; Child, Preschool; Chromatography, Liquid; Epilepsy; Female; Humans; Infant; Lysine; Male; Mass Screening; Picolinic Acids; Pipecolic Acids; Tandem Mass Spectrometry | 2019 |
Lysine pathway metabolites and the risk of type 2 diabetes and cardiovascular disease in the PREDIMED study: results from two case-cohort studies.
Topics: 2-Aminoadipic Acid; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet, Mediterranean; Female; Humans; Incidence; Lysine; Male; Middle Aged; Pipecolic Acids; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Risk Reduction Behavior; Time Factors; Treatment Outcome | 2019 |
Enhancement of pipecolic acid production by the expression of multiple lysine cyclodeaminase in the Escherichia coli whole-cell system.
Topics: Ammonia-Lyases; Biotransformation; Culture Media; Escherichia coli; Fermentation; Gene Expression; Lysine; Metabolic Engineering; Metals; Pipecolic Acids; Tandem Repeat Sequences; Time Factors | 2020 |
Clinical and biochemical outcome of a patient with pyridoxine-dependent epilepsy treated by triple therapy (pyridoxine supplementation, lysine-restricted diet, and arginine supplementation).
Topics: Arginine; Biomarkers; Child, Preschool; Dietary Supplements; Epilepsy; Female; Humans; Lysine; Pipecolic Acids; Pyridoxine; Treatment Outcome | 2021 |
An artificial pathway for trans-4-hydroxy-L-pipecolic acid production from L-lysine in Escherichia coli.
Topics: Bacterial Outer Membrane Proteins; Catalase; Escherichia coli; Escherichia coli Proteins; Glucose 1-Dehydrogenase; Hydroxy Acids; Lysine; Membrane Transport Proteins; Mixed Function Oxygenases; Pharmaceutical Preparations; Pipecolic Acids | 2022 |
Systems metabolic engineering upgrades Corynebacterium glutamicum for selective high-level production of the chiral drug precursor and cell-protective extremolyte L-pipecolic acid.
Topics: Corynebacterium glutamicum; Fermentation; Glucose; Lysine; Metabolic Engineering; Oxidoreductases; Prodrugs | 2023 |