Page last updated: 2024-08-17

lysine and orotic acid

lysine has been researched along with orotic acid in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	47 (79.66)	18.7374
1990's	4 (6.78)	18.2507
2000's	5 (8.47)	29.6817
2010's	1 (1.69)	24.3611
2020's	2 (3.39)	2.80

Authors

Authors	Studies
Milner, JA; Prior, RL; Visek, WJ	1
Artemenko, NK; Freidlin, IS; Lyzlova, SN; Nersesova, LS; Petrova, TA	1
Visek, WJ	1
Zieve, L	1
Brusilow, SW; Rajantie, J; Simell, O; Sipilä, I; Valle, DL	1
Kato, T; Mizutani, N; Sano, M	1
Bachmann, C; Colombo, JP; Dionisi Vici, C; Gambarara, M; Sabetta, G	1
Alexiev, C; Golovinsky, E; Halacheva, K; Hubenova, A; Pajpanova, T; Spassova, M; Zhelev, Z	1
de Parscau, L; Divry, P; Guibaud, P; Hermier, M; Vianey-Liaud, C	1
Barth, CA; de Vrese, M	1
Ord, MG; Stocken, LA	1
Christophe, J; Vandermeers-Piret, MC	1
Cummins, JE; Rusch, HP	1
Meerson, FZ; Pomoinitsky, VD	1
Nasonov, AS	1
Arnold, EA; Young, KE	1
Paik, WK; Pearson, DB	1
Latimer, RG; Mandel, HG; Riis, M	1
Conrad, ME; Polet, H	1
Bäckström, S	1
Cerna, I; Fay, PJ; Klubes, P	1
Morita, T; Ogata, K; Tsurugi, K	1
Lee, HW; Paik, WK	1
Cox, BM; Osman, OH	1
Chae, CB; Irvin, JL; Krasny, H; Piantadosi, C; Williams, A	1
Barceló, P; Ferré, LA; Salvatella Viñals, J	1
Dixon, GH; Smithies, O; Sung, MT	1
Caroli, J; Goutand, G; Lemonnier, F	1
Faloona, GR; Fried, M; Stewart, BN	1
Borgatti, AR; Lenaz, G; Sechi, AM	2
Held, I; Koenig, H; Wells, W	1
Moruzzi, G; Sechi, AM; Viviani, R	1
Sanchez, S	1
Booth, BA; Sartorelli, AC	1
Bucknall, RA; Carter, SB	1
Cohen, S; Hoober, JK	1
Ifft, KH; Kari, FW; Ulman, EA; Visek, WJ	1
Hevia, P; Kari, FW; Ulman, EA; Visek, WJ	1
Fico, ME; Hassan, AS; Milner, JA	1
Dorfman, RH; Grubmeyer, C; Ozturk, DH; Sacchettini, JC; Scapin, G	1
Grunstein, M; Ling, X; Thompson, JS	1
Kirchgessner, M; Kreuzer, M; Vertesy, E	1
Donati, MA; Filippi, L; Resti, M; Zammarchi, E	1
Lukkarinen, M; Mattila, K; Näntö-Salonen, K; Pulkki, K; Simell, O	1
Andersen, GR; Kinzy, TG; Nyborg, J; Pedersen, L; Valente, L	1
Holden, HM; Neal, TM; Phillips, GN; Raushel, FM; Thoden, JB	1
BRATTGARD, SO; HYDEN, H; SJOSTRAND, J	1
HATAKEYAMA, T	1
ALLFREY, VG; FRENSTER, JH; MIRSKY, AE	1
FUJIOKA, M; LIEBERMAN, I	1
CAROLI, J; HAGEGE, A; LEMONNIER, F; MASSON, S	1
BARRE, Y; CAROLI, J; MOLLE, J; TREMOLIERES, J; VAN DEN DRIESSCHE, J; VIGNERON, M	1
KORNACKA, L; MALEC, J; WOJNAROWSKA, M; ZAKRZEWSKI, K	1
Basran, J; Combe, JP; Hothi, P; Leys, D; Munro, AW; Rigby, SE; Scrutton, NS	1
Ma, C; Wang, X; Xu, P	1
Dong, YH; Gao, ZQ; Ji, CN; Li, LF; Liu, CP; Liu, Y; Su, XD; Xu, JH	1
Gornbein, JA; Koos, BJ	1
Hall, PL; Wilcox, WR; Wittenauer, AL	1

Reviews

1 review(s) available for lysine and orotic acid

Article	Year
Conditional deficiencies of ornithine or arginine. Journal of the American College of Nutrition, 1986, Volume: 5, Issue:2 Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Arginine; Citrulline; Female; Glycine; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Lysine; Models, Biological; Ornithine; Orotic Acid; Pregnancy; Protein Deficiency; Urease	1986

Other Studies

58 other study(ies) available for lysine and orotic acid

Article	Year
Urea, citrate and orotate excretion in growing rats fed amino acid-deficient diets. The Journal of nutrition, 1975, Volume: 105, Issue:2 Topics: Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Arginine; Citrates; Deficiency Diseases; Lysine; Male; Orotic Acid; Rats; Urea	1975
[Changes in the functional activity of macrophages, their morphology and metabolism under the influence of several biologically active substances]. Tsitologiia, 1975, Volume: 17, Issue:2 Topics: Ascorbic Acid; Carbon Radioisotopes; Cathepsins; Chloramphenicol; Chloroquine; Creatine Kinase; Culture Techniques; Cycloheximide; Dactinomycin; Lipopolysaccharides; Lysine; Macrophages; Orotic Acid; Peritoneum; Phagocytosis; Protein Biosynthesis; Puromycin; Rifampin; RNA; Tetracycline; Uridine	1975
Arginine needs, physiological state and usual diets. A reevaluation. The Journal of nutrition, 1986, Volume: 116, Issue:1 Topics: Animals; Arginine; Body Weight; Creatine; Diet; Fatty Liver; Female; Humans; Lysine; Nutritional Requirements; Orotic Acid; Pregnancy; Wounds and Injuries	1986
Waste nitrogen excretion via amino acid acylation: benzoate and phenylacetate in lysinuric protein intolerance. Pediatric research, 1986, Volume: 20, Issue:11 Topics: Acylation; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Benzoates; Benzoic Acid; Child; Child, Preschool; Creatinine; Glutamine; Hippurates; Humans; Lysine; Nitrogen; Orotic Acid; Phenylacetates; Urea	1986
Inhibitory effect of intravenous lysine infusion on urea cycle metabolism. European journal of pediatrics, 1987, Volume: 146, Issue:1 Topics: Adolescent; Amino Acids; Ammonia; Child; Citric Acid Cycle; Citrulline; Depression, Chemical; Female; Humans; Infusions, Intravenous; Lysine; Male; Orotic Acid; Putrescine; Urea	1987
Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome: low creatine excretion and effect of citrulline, arginine, or ornithine supplement. Pediatric research, 1987, Volume: 22, Issue:3 Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Child, Preschool; Citrulline; Creatine; Female; Humans; Lysine; Male; Ornithine; Orotic Acid; Syndrome	1987
Lysine-orotate potentiates the toxicity of an extract of the mushroom Amanita phalloides. Toxicon : official journal of the International Society on Toxinology, 1988, Volume: 26, Issue:6 Topics: Amanitins; Animals; Drug Synergism; Lysine; Male; Mice; Orotic Acid; Protein Binding	1988
[Protein intolerance with lysinuria. Value of orotic aciduria in adjusting treatment with citrulline]. Archives francaises de pediatrie, 1988, Volume: 45, Issue:10 Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Diamino; Ammonia; Biological Transport; Cell Membrane; Citrulline; Consanguinity; Dietary Proteins; Humans; Lysine; Male; Orotic Acid; Osteoporosis	1988
Influence of lysine on urea cycle activity and orotate formation in the isolated perfused rat liver. Biological chemistry Hoppe-Seyler, 1985, Volume: 366, Issue:5 Topics: Ammonia; Animals; In Vitro Techniques; Kinetics; Liver; Lysine; Male; Ornithine; Orotic Acid; Perfusion; Rats; Rats, Inbred Strains; Urea	1985
Uptake of amino acids and nucleic acid precursors by regenerating rat liver. The Biochemical journal, 1972, Volume: 129, Issue:1 Topics: Adenine; Adrenalectomy; Amino Acids; Animals; Dactinomycin; Hepatectomy; Liver; Liver Regeneration; Lysine; Male; Ornithine; Orotic Acid; Phenylalanine; Rats; RNA; Thymidine; Tritium; Tyrosine; Uridine; Valine	1972
[Effects of lysine deficiency on the rat liver]. Archives internationales de physiologie et de biochimie, 1964, Volume: 72, Issue:4 Topics: Animals; Carbon Isotopes; Deficiency Diseases; In Vitro Techniques; Leucine; Liver; Lysine; Orotic Acid; Protein Biosynthesis; Rats; RNA; Thymidine; Uracil	1964
Limited DNA synthesis in the absence of protein synthesis in Physarum polycephalum. The Journal of cell biology, 1966, Volume: 31, Issue:3 Topics: Anti-Bacterial Agents; Carbon Isotopes; Cell Division; Cell Nucleus; Cycloheximide; DNA; Floxuridine; Leucine; Lysine; Myxomycetes; Orotic Acid; Protein Biosynthesis; Thymidine; Tritium	1966
The role of high-energy phosphate compounds in the development of cardiac hypertrophy. Journal of molecular and cellular cardiology, 1972, Volume: 4, Issue:6 Topics: Acclimatization; Adenosine Triphosphate; Alanine; Animals; Aorta; Atmosphere Exposure Chambers; Carbon Isotopes; Cardiomegaly; Cell Nucleus; DNA; Lysine; Male; Methionine; Mitochondria, Muscle; Orotic Acid; Oxygen; Rats; RNA; Thymidine; Tritium	1972
[Metabolism of information RNAs from rat liver free and membrane-bound polyribosomes in a cell-free system of protein synthesis]. Doklady Akademii nauk SSSR, 1974, Aug-02, Volume: 217, Issue:5 Topics: Animals; Carbon Radioisotopes; Cell-Free System; Centrifugation, Zonal; Liver; Lysine; Male; Membranes; Orotic Acid; Polyribosomes; Protein Biosynthesis; Protein Precursors; Rats; RNA, Messenger; RNA, Ribosomal	1974
Heterogeneity of chromatin: fractionation of sonicated rat liver chromatin by partial precipitation with Mg2+. Archives of biochemistry and biophysics, 1974, Volume: 164, Issue:1 Topics: Animals; Binding Sites; Centrifugation, Density Gradient; Chromatin; Chromosomes; DNA; Electrophoresis, Polyacrylamide Gel; Histones; Liver; Lysine; Magnesium; Male; Molecular Weight; Nucleoproteins; Orotic Acid; Peptides; Protein Binding; Rats; RNA; Solubility; Spectrophotometry, Ultraviolet; Templates, Genetic; Tritium; Ultracentrifugation; Ultrasonics	1974
Studies on histone acetylation during thyroxine-induced amphibian metamorphosis. Experimental cell research, 1972, Volume: 73, Issue:1 Topics: Acetates; Animals; Carbon Isotopes; Electrophoresis; Histones; Kinetics; Lectins; Lysine; Metamorphosis, Biological; Orotic Acid; Rana catesbeiana; RNA; Thyroxine; Trichloroacetic Acid; Tritium	1972
The actions of thioguanine in Bacillus cereus. Biochemical pharmacology, 1965, Volume: 14, Issue:5 Topics: Bacillus cereus; DNA, Bacterial; Flagella; Glycine; Guanine; In Vitro Techniques; Lysine; Mercaptopurine; Orotic Acid; Penicillinase; Phosphates; RNA, Bacterial; Thioguanine; Uracil	1965
Malaria: extracellular amino acid requirements for in vitro growth of erythrocytic forms of Plasmodium knowlesi. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 127, Issue:1 Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Culture Techniques; Cystine; DNA; Erythrocytes; Glutamine; Haplorhini; Histidine; Isoleucine; Lysine; Methionine; Orotic Acid; Plasmodium; Tyrosine	1968
[Passage of radioactive substances between a labelled graft and its unmarked host. Autoradiographic study of sea urchin embryo submitted to transplantation]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1969, Oct-29, Volume: 269, Issue:17 Topics: Alanine; Amino Acids; Animals; Autoradiography; Echinodermata; Embryo Transfer; Leucine; Lysine; Mosaicism; Nucleic Acids; Orotic Acid; Transplantation, Homologous; Tritium; Uridine	1969
Effect of chlorpromazine on cell wall biosynthesis and incorporation of orotic acid into nucleic acids in Bacillus megaterium. Biochemical pharmacology, 1971, Volume: 20, Issue:2 Topics: Adenine; Bacillus megaterium; Bacterial Proteins; Carbon Isotopes; Cell Wall; Chlorpromazine; DNA, Bacterial; Formates; Lysine; Models, Biological; Nucleic Acids; Orotic Acid; Pimelic Acids; Promazine; RNA; RNA, Bacterial; Sulfoxides; Thymidine; Time Factors; Trifluoperazine; Uridine	1971
Studies on the metabolism of ribosomal structural proteins of regenerating rat liver. Sites of biosynthesis of structural proteins of large subunit and of their assembly with RNA moiety. European journal of biochemistry, 1972, Jan-31, Volume: 25, Issue:1 Topics: Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Cytoplasm; Electrophoresis, Disc; Hepatectomy; Leucine; Liver; Liver Regeneration; Lysine; Male; Nucleoproteins; Orotic Acid; Protein Biosynthesis; Rats; Ribosomes; RNA, Ribosomal; Tritium; Valine	1972
Histone methylation during hepatic regeneration in rat. Biochimica et biophysica acta, 1972, Aug-16, Volume: 277, Issue:1 Topics: Animals; Arginine; Carbon Isotopes; Cytoplasm; DNA; Hepatectomy; Histones; Kinetics; Liver; Liver Regeneration; Lysine; Male; Methylation; Methyltransferases; Orotic Acid; Proteins; Rats; RNA; S-Adenosylmethionine; Thymidine; Tritium	1972
Inhibition of the development of tolerance to morphine in rats by drugs which inhibit ribonucleic acid or protein synthesis. British journal of pharmacology, 1970, Volume: 38, Issue:1 Topics: Animals; Brain; Carbon Isotopes; Cycloheximide; Dactinomycin; Depression, Chemical; Drug Tolerance; Female; Fluorouracil; Lysine; Male; Mercaptopurine; Morphine; Orotic Acid; Protein Biosynthesis; Puromycin; Rats; RNA	1970
Inhibition of thymidine phosphorylation and DNA and histone synthesis in Ehrlich ascites carcinoma. Cancer research, 1970, Volume: 30, Issue:11 Topics: Aldehydes; Animals; Arginine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Thin Layer; Cycloheximide; Cytarabine; Cytoplasm; DNA; Glycine; Histones; Hydroxyurea; In Vitro Techniques; Lysine; Mice; Mitomycins; Nucleotides; Orotic Acid; Puromycin; Thiosemicarbazones; Thymidine; Tritium	1970
[Results of personal experience with a sulfamide preparation associated with lysine orotate and pyridoxine hydrochloride, in the treatment of rheumatism of degenerative origin]. Revista espanola de reumatismo y enfermedades osteoarticulares, 1970, Volume: 13, Issue:5 Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Lysine; Male; Middle Aged; Orotic Acid; Pyridoxine; Sulfonamides	1970
Phosphorylation and synthesis of histones in regenerating rat liver. The Journal of biological chemistry, 1971, Mar-10, Volume: 246, Issue:5 Topics: Acrylates; Amino Acids; Animals; Autoradiography; Cell Nucleus; Chromatography, Ion Exchange; Electrophoresis; Gels; Hepatectomy; Histones; Hydrogen-Ion Concentration; Liver; Liver Regeneration; Lysine; Male; Orotic Acid; Osmolar Concentration; Phosphates; Phosphopeptides; Phosphorus Isotopes; Polymers; Rats; RNA; Starch; Tritium	1971
[Action of lysine on the hyperammoniema of the cirrhotic patient]. La Presse medicale, 1971, May-08, Volume: 7, Issue:23 Topics: Amino Acids; Ammonia; Humans; Injections, Intravenous; Liver Cirrhosis; Lysine; Male; Middle Aged; Orotic Acid; Perfusion; Time Factors	1971
The effects of actinomycin D on the siosynthesis of plasma lipoproteins. Biochemistry, 1968, Volume: 7, Issue:2 Topics: Animals; Carbon Isotopes; Centrifugation, Zonal; Dactinomycin; Depression, Chemical; Lipoproteins; Liver; Lysine; Male; Orotic Acid; Perfusion; Proteins; Rats; Templates, Genetic; Tritium	1968
[Effects of lysine and orotic acid on the lipid composition of the brain of lysine-deficient rats]. Bollettino della Societa italiana di biologia sperimentale, 1968, Dec-31, Volume: 44, Issue:24 Topics: Animals; Brain; Deficiency Diseases; Lipid Metabolism; Lysine; Orotic Acid; Rats	1968
[Changes of blood and hepatic cholesterol in lysine deficient rats: effect of lysine and orotic acid]. Bollettino della Societa italiana di biologia sperimentale, 1968, Dec-31, Volume: 44, Issue:24 Topics: Animals; Cholesterol; Deficiency Diseases; Liver; Lysine; Orotic Acid; Rats	1968
Metabolic effects of azaserine in rat brain. Journal of neurochemistry, 1969, Volume: 16, Issue:4 Topics: Adenine; Animals; Azaserine; Brain; Carbon Isotopes; Centrifugation; Chromatography, Ion Exchange; Chromatography, Paper; Female; Glycine; Lysine; Nerve Tissue Proteins; Nucleotides; Orotic Acid; Paraplegia; Phenylalanine; Purines; Pyrimidines; Rats; RNA; Spectrum Analysis; Tritium	1969
Effect of orotic acid in lysine deficient rats. Internationale Zeitschrift fur Vitaminforschung. International journal of vitamin research. Journal international de vitaminologie, 1969, Volume: 39, Issue:1 Topics: Animals; Deficiency Diseases; Depression, Chemical; Diet; Growth; Lipids; Liver; Lysine; Nucleic Acids; Orotic Acid; Protein Biosynthesis; Rats	1969
[The formation and role of nucleoli in the oocytes of Triturus helveticus Raz--an autoradiographic and ultrastructural study]. Journal of embryology and experimental morphology, 1969, Volume: 22, Issue:1 Topics: Animals; Autoradiography; Cell Nucleolus; Chromosomes; Female; Histocytochemistry; Lysine; Microscopy, Electron; Orotic Acid; Ovum; Tritium; Urodela	1969
The synergistic anti-neoplastic activity of combinations of mitomycins with either 6-thioguanine or 5-fluorouracil. Cancer research, 1965, Volume: 25, Issue:9 Topics: Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Synergism; Female; Fluorouracil; In Vitro Techniques; Leukemia L1210; Lysine; Male; Mice; Mitomycins; Mortality; Neoplasm Proteins; Neoplasm Transplantation; Orotic Acid; RNA, Neoplasm; Sarcoma 180; Thioguanine; Thymidine; Thymidine Kinase	1965
A reversible inhibitor of nucleic acid synthesis. Nature, 1967, Mar-18, Volume: 213, Issue:5081 Topics: Animals; Benzimidazoles; Cattle; Chick Embryo; Culture Media; Culture Techniques; DNA; Fibroblasts; HeLa Cells; Kidney; L Cells; Lysine; Nucleosides; Orotic Acid; RNA; Thymidine; Tritium; Uridine	1967
Epidermal growth factor. I. The stimulation of protein and ribonucleic acid synthesis in chick embryo epidermis. Biochimica et biophysica acta, 1967, Apr-18, Volume: 138, Issue:2 Topics: Animals; Carbon Isotopes; Chick Embryo; Culture Techniques; Dactinomycin; Growth Substances; Lysine; Orotic Acid; Protein Biosynthesis; Proteins; Puromycin; RNA; Skin; Submandibular Gland; Thymidine; Uridine	1967
Fatty liver of growing rats fed excess lysine and its prevention by adenine or allopurinol. Lipids, 1981, Volume: 16, Issue:5 Topics: Adenine; Allopurinol; Animals; Arginine; Diet; Fatty Liver; Lipid Metabolism; Liver; Lysine; Male; Orotic Acid; Rats	1981
Orotic aciduria caused by feeding excess lysine to growing rats. The Journal of nutrition, 1981, Volume: 111, Issue:10 Topics: Ammonia; Animals; Arginine; Body Weight; Creatinine; Eating; Lysine; Male; Orotic Acid; Rats; Rats, Inbred Strains; Urea	1981
The influence of excess lysine on urea cycle operation and pyrimidine biosynthesis. The Journal of nutrition, 1982, Volume: 112, Issue:10 Topics: Amino Acids; Ammonium Chloride; Animals; Arginase; Arginine; Dose-Response Relationship, Drug; Liver; Lysine; Orotic Acid; Rats; Rats, Inbred Strains; Urea	1982
Structure and function of Salmonella typhimurium orotate phosphoribosyltransferase: protein complementation reveals shared active sites. Biochemistry, 1995, Aug-29, Volume: 34, Issue:34 Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Chromatography, Ion Exchange; Conserved Sequence; Electrophoresis, Polyacrylamide Gel; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Orotate Phosphoribosyltransferase; Orotic Acid; Phosphoribosyl Pyrophosphate; Protein Conformation; Salmonella typhimurium; Sequence Homology, Amino Acid	1995
Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast. Nature, 1994, May-19, Volume: 369, Issue:6477 Topics: Amino Acid Sequence; Chromosomes, Fungal; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Histones; Lysine; Molecular Sequence Data; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Saccharomyces cerevisiae; Telomere	1994
Response of renal orotic acid and creatinine to treatments affecting metabolic protein supply of ruminants. Archiv fur Tierernahrung, 1995, Volume: 48, Issue:1-2 Topics: Allantoin; Animal Feed; Animals; Creatinine; Dietary Proteins; Kidney; Lysine; Male; Orotic Acid; Rumen; Ruminants; Sheep; Urea	1995
Cryptogenic hepatitis masking the diagnosis of ornithine transcarbamylase deficiency. Journal of pediatric gastroenterology and nutrition, 1996, Volume: 22, Issue:4 Topics: Absorption; Ammonia; Arginine; Child, Preschool; Citrulline; Diagnosis, Differential; Dietary Proteins; Female; Glutamine; Hepatitis; Humans; Infant; Lysine; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Urea	1996
Effect of lysine infusion on urea cycle in lysinuric protein intolerance. Metabolism: clinical and experimental, 2000, Volume: 49, Issue:5 Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acid Transport Systems, Basic; Amino Acids; Ammonia; Carrier Proteins; Female; Humans; Lysine; Male; Membrane Proteins; Middle Aged; Mutation; Orotic Acid; Urea	2000
Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex. Nature structural biology, 2001, Volume: 8, Issue:6 Topics: Amino Acid Substitution; Binding Sites; Carbohydrate Metabolism; Crystallography, X-Ray; Guanosine Diphosphate; Lysine; Magnesium; Models, Molecular; Mutation; Orotic Acid; Peptide Elongation Factor 1; Protein Conformation; Yeasts	2001
Molecular structure of dihydroorotase: a paradigm for catalysis through the use of a binuclear metal center. Biochemistry, 2001, Jun-19, Volume: 40, Issue:24 Topics: Amino Acid Sequence; Aryldialkylphosphatase; Aspartic Acid; Binding Sites; Carbamyl Phosphate; Catalysis; Crystallography, X-Ray; Dihydroorotase; Dimerization; Escherichia coli; Esterases; Humans; Lysine; Molecular Sequence Data; Orotic Acid; Structure-Activity Relationship; Zinc	2001
Incorporation of orotic acid-14c and lysine-14c in regenerating single nerve cells. Nature, 1958, Sep-20, Volume: 182, Issue:4638 Topics: Biochemical Phenomena; Lysine; Neurons; Orotic Acid; Regeneration	1958
[Studies on nutrition and hepatic injury. 4. Studies on experimental fatty liver; effects of addition of lipoic acid, orotic acid, lvsine, threonine, and fermented sovbeans]. Paediatria Japonica, 1961, Volume: 65 Topics: Fatty Liver; Glycine max; Liver Diseases; Lysine; Nutritional Status; Orotic Acid; Thioctic Acid; Threonine	1961
REPRESSED AND ACTIVE CHROMATIN ISOLATED FROM INTERPHASE LYMPHOCYTES. Proceedings of the National Academy of Sciences of the United States of America, 1963, Volume: 50 Topics: Alanine; Animals; Carbon Isotopes; Cattle; Chromatin; Chromosomes; DNA; Electrons; Genetics; Interphase; Lymphocytes; Lysine; Microscopy; Microscopy, Electron; Nucleosides; Orotic Acid; Proteins; Research; Thymus Gland	1963
A ZN++ REQUIREMENT FOR SYNTHESIS OF DEOXYRIBONUCLEIC ACID BY RAT LIVER. The Journal of biological chemistry, 1964, Volume: 239 Topics: Antimetabolites; Cell Nucleus; DNA; Edetic Acid; Hepatectomy; Liver; Lysine; Magnesium; Metabolism; Orotic Acid; Perfusion; Pharmacology; Phenylalanine; Proteins; Rats; Research; Thymidine; Zinc	1964
[A NEW TREATMENT OF EXCESS BLOOD AMMONIA IN CIRRHOTIC PATIENTS: LYSINE OROTATE]. Revue medico-chirurgicale des maladies du foie, 1964, Volume: 39 Topics: Ammonia; Blood Chemical Analysis; Drug Therapy; Humans; Liver Cirrhosis; Lysine; Orotic Acid	1964
[LYSINE OROTATE IN HEPATOLOGY]. La Presse medicale, 1964, Nov-14, Volume: 72 Topics: Alcoholism; Chemistry, Pharmaceutical; Drug Therapy; Gastroenterology; Hepatic Encephalopathy; Hepatitis; Hepatitis A; Humans; Jaundice; Liver Cirrhosis; Lysine; Orotic Acid; Portacaval Shunt, Surgical; Toxicology	1964
EFFECT OF PURINES AND SOME OF THEIR ANALOGUES ON PROTEIN AND RNA SYNTHESIS IN ISOLATED NUCLEI. Biochimica et biophysica acta, 1964, Dec-16, Volume: 91 Topics: Antibody Formation; Antimetabolites; Antineoplastic Agents; Carbon Isotopes; Cell Nucleus; Cytosine; Guanine; Leucine; Leukocytes; Lysine; Mercaptopurine; Metabolism; Orotic Acid; Pharmacology; Proteins; Purines; Research; RNA; Thioguanine; Uracil; Uric Acid; Xanthines	1964
Lys-D48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase B of Lactococcus lactis. The Journal of biological chemistry, 2006, Jun-30, Volume: 281, Issue:26 Topics: Catalysis; Dihydroorotate Dehydrogenase; Dimerization; Electrochemistry; Electron Transport; Flavin Mononucleotide; Flavins; Lactococcus lactis; Lysine; Mutagenesis, Site-Directed; NAD; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Protein Structure, Tertiary; Tyrosine	2006
Orotate phosphoribosyltransferase from Corynebacterium ammoniagenes lacking a conserved lysine. Journal of bacteriology, 2007, Volume: 189, Issue:24 Topics: Bacterial Proteins; Cations, Divalent; Chromatography, Gel; Cloning, Molecular; Coenzymes; Conserved Sequence; Corynebacterium; Dimerization; Diphosphates; Enzyme Stability; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Molecular Weight; Orotate Phosphoribosyltransferase; Orotic Acid; Phosphoribosyl Pyrophosphate; Recombinant Proteins; Sequence Analysis, DNA; Uridine Monophosphate	2007
Structure of the putative dihydroorotate dehydrogenase from Streptococcus mutans. Acta crystallographica. Section F, Structural biology and crystallization communications, 2011, Feb-01, Volume: 67, Issue:Pt 2 Topics: Amino Acid Sequence; Binding Sites; Catalysis; Conserved Sequence; Crystallography, X-Ray; Dental Caries; Dihydroorotate Dehydrogenase; Dimerization; Escherichia coli; Flavin Mononucleotide; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Subunits; Pyrimidines; Recombinant Proteins; Sequence Homology, Amino Acid; Streptococcus mutans; Substrate Specificity; X-Ray Diffraction	2011
Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming. American journal of obstetrics and gynecology, 2021, Volume: 224, Issue:2 Topics: Adult; Alanine; Arginine; Carnitine; Case-Control Studies; Diabetes, Gestational; Diet Therapy; Dopamine; Early Diagnosis; Epigenesis, Genetic; Female; Fetal Development; Gestational Age; Glucose Tolerance Test; Glucuronides; Humans; Hypoglycemic Agents; Lactones; Lysine; Meglutol; Metabolomics; Neopterin; Orotic Acid; Phenols; Pregnancy; Ribonucleosides; Sulfides	2021
Proximal urea cycle defects are challenging to detect with newborn screening: Results of a prospective pilot study using post-analytical tools. American journal of medical genetics. Part C, Seminars in medical genetics, 2022, Volume: 190, Issue:2 Topics: Amino Acids; Ammonia; Glutamine; Humans; Infant, Newborn; Lysine; Neonatal Screening; Orotic Acid; Pilot Projects; Prospective Studies; Urea	2022