lysine has been researched along with nadp in 141 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (30.50) | 18.7374 |
| 1990's | 31 (21.99) | 18.2507 |
| 2000's | 39 (27.66) | 29.6817 |
| 2010's | 20 (14.18) | 24.3611 |
| 2020's | 8 (5.67) | 2.80 |
| Authors | Studies |
|---|---|
| Colman, RF | 1 |
| Dallocchio, F; Negrini, R; Rippa, M; Signorini, M | 1 |
| Zanetti, G | 1 |
| Cosson, MP; Gros, C; Pantaloni, D; Talbot, JC | 1 |
| Hack, E; Kemp, JD | 1 |
| Tabita, FR; Whitman, WB | 1 |
| Bellini, T; Dallocchio, F; Rippa, M; Signorini, M | 1 |
| Dancis, J; Hutzler, J | 2 |
| Levy, HR; Milhausen, M | 1 |
| Coudert, M; Lemal, J; Vandecasteele, JP | 1 |
| Dallocchio, F; Hanau, S; Rippa, M | 1 |
| Chen, Z; Colman, RF; Haeffner-Gormley, L; Zalkin, H | 1 |
| Shen, S; Strobel, HW | 1 |
| Bajorath, J; Farnum, M; Fine, RM; Fitzgerald, G; Hagler, AT; Kitson, DH; Kraut, J; Li, ZQ | 1 |
| Aliverti, A; Gadda, G; Ronchi, S; Zanetti, G | 1 |
| Stephanopoulos, G; Vallino, JJ | 1 |
| Linder, D; Lumper, L; Müller, K | 1 |
| Appleman, R; Blakley, RL; Freisheim, JH; Huang, S; Sheridan, RP; Tan, XH; Thompson, PD; Venkataraghavan, R | 1 |
| Dean, AM; Koshland, DE; Lee, MH | 1 |
| Inano, H; Kurihara, S | 1 |
| Baccanari, DP; Delcamp, TJ; Forsch, RA; Freisheim, JH; Rosowsky, A; Solan, VC | 1 |
| Bohren, KM; von Wartburg, JP; Wermuth, B | 1 |
| Berden, JA; Hartog, AF; Persson, B; Rydström, J | 1 |
| Biondi, PA; Cidaria, D; Ronchi, S; Zanetti, G | 1 |
| Blumenthal, KM; Smith, EL | 1 |
| Broquist, HP; Guengerich, FP; Snyder, JJ | 1 |
| Broquist, HP; Guengerich, FP | 1 |
| Chung, AE; Edwards, DJ; Heinrikson, RL | 1 |
| Fellows, FC | 1 |
| Gilvarg, C; Tamir, H | 1 |
| Fujioka, M; Nakatani, Y | 1 |
| Cornell, NW; Krebs, HA; Lund, P | 1 |
| Broquist, HP; Jones, EE | 1 |
| Dorfman, RI; Forchielli, E; Menon, KM | 1 |
| Levine, L; Seaman, E; Setlow, P; van Vunakis, H | 1 |
| LéJohn, HB; Meuser, R; Stevenson, RM | 1 |
| Henderson, LM; Hiles, RA; Triebwasser, KC | 1 |
| Fujioka, M; Higashino, K; Yamamura, Y | 1 |
| Geroch, ME; Levy, HR; Olive, C | 1 |
| LéJohn, HB | 1 |
| Piszkiewicz, D; Smith, EL | 2 |
| Bhattacharjee, JK; Sinha, AK | 1 |
| Frieden, C; Goldin, BR | 1 |
| Nesheim, MC; Wang, SH | 1 |
| Hamamoto, I; Ichikawa, Y | 1 |
| Kolattukudy, PE; Poulose, AJ; Rogers, L | 1 |
| Kjellén, KG; Neujahr, HY | 1 |
| Chang, GG; Chang, TC; Huang, TM | 1 |
| Eppink, MH; Schreuder, HA; Van Berkel, WJ | 2 |
| Chen, HH; Chen, S; Deng, PS; Forrest, GL; Massey, V; Tedeschi, G | 1 |
| Terada, T | 1 |
| Katiyar, SS; Pandey, A | 1 |
| Ichikawa, Y; Wu, RF | 1 |
| Borhani, DW; Petrash, JM; Quiocho, FA; Tarle, I; Wilson, DK | 1 |
| Higuchi, T; Imamura, Y; Otagiri, M | 1 |
| Diekmann, H; Macheroux, P; Plattner, HJ; Romaguera, A | 1 |
| Cho, SW; Choi, SY; Hong, JW; Lee, SJ | 1 |
| Albee, L; Chitnis, PR; Chitnis, VP; Golbeck, JH; Jungs, YS | 1 |
| Fontecilla-Camps, JC; Frey, M; Gomez-Moreno, C; Medina, M; Serre, L; Vellieux, F | 1 |
| Ballou, DP; Entsch, B; Moran, GR; Palfey, BA | 1 |
| Deyashiki, Y; Hara, A; Iwasa, H; Matsuura, K; Miwa, G; Sato, K; Tamada, Y | 1 |
| Iyengar, L; Katiyar, SS; Pandey, A | 1 |
| Marrone, L; Viswanatha, T | 1 |
| Higashino, K | 1 |
| Burgess, BK; Jung, YS; Roberts, VA; Stout, CD | 1 |
| Bizouarn, T; Fjellström, O; Hu, X; Rydström, J; Zhang, J | 1 |
| Ganago, AO; Golbeck, JH; Jung, YS; McIntosh, L; Schulz, R; Vassiliev, IR; Yu, J | 1 |
| Liu, H; Mount, DB; Nasjletti, A; Wang, W | 1 |
| Ehmann, DE; Gehring, AM; Walsh, CT | 1 |
| Poulsen, LL; Robertus, JD; Suh, JK; Ziegler, DM | 1 |
| Chang, GG; Chin, TY; Chou, WY; Kuo, CC; Tsai, LC | 1 |
| Johansson, E; Lindqvist, Y; Schneider, G; Steffens, JJ | 1 |
| Adams, MJ; Ciccone, T; Cosgrove, MS; Davino, MH; Fairbairn, L; Levy, HR; Lin, Y; Vought, V | 1 |
| Hempel, J; Kuo, I; Lindahl, R; Perozich, J | 1 |
| Sciotti, M; Wermuth, B | 1 |
| Karginova, O; Lebedev, N; McIvor, W; Timko, MP | 1 |
| Bazzi, MD; Duhaiman, AS; Rabbani, N | 1 |
| Fujioka, M; Gomi, T; Huang, Y; Komoto, J; Ogawa, H; Takata, Y; Takusagawa, F; Yamada, T | 1 |
| Jeong, EY; Kim, IS; Lee, H | 1 |
| Aparicio, JF; Hijarrubia, MJ; Martín, JF | 1 |
| Heyes, DJ; Hunter, CN | 1 |
| Heinzle, E; Wittmann, C | 1 |
| Berndt, KD; Chiaraluce, R; Consalvi, V; Ladenstein, R; Lebbink, JH | 1 |
| Bhattacharjee, JK; Guo, S | 1 |
| Farrés, J; Fita, I; Ochoa, WF; Parés, X; Rosell, A; Valencia, E | 2 |
| Bathe, B; Burke, K; de Graaf, AA; Dunican, LK; Hans, S; Marx, A; McCormack, AC; Möckel, B; O'Donohue, M; Stapleton, C | 1 |
| BARRATT, RW | 1 |
| Chen, TS; Lin, TY | 1 |
| Fraaije, MW; Janssen, DB; Kamerbeek, NM | 1 |
| Hicks, SN; Howell, EE; Minor, KH; Smiley, RD; Stinnett, LG | 1 |
| Esaki, N; Kakutani, R; Kurihara, T; Mihara, H; Muramatsu, H; Ueda, M; Yasuda, M | 1 |
| Leitgeb, S; Nidetzky, B; Petschacher, B; Wilson, DK | 1 |
| Christendat, D; Collart, F; Joachimiak, A; Korolev, S; Koroleva, O; Singh, S; Zarembinski, T | 1 |
| Baer, BR; Henne, KR; Rettie, AE | 1 |
| Carlisle-Moore, L; Gordon, CR; Machutta, CA; Miller, WT; Tonge, PJ | 1 |
| Colman, RF; Lee, P | 1 |
| Chang, GG; Hsieh, JY; Hung, HC; Liu, GY | 1 |
| Ge, L; Seah, SY | 1 |
| Kreimeyer, A; Lechaplais, C; Médigue, C; Perret, A; Salanoubat, M; Vallenet, D; Weissenbach, J | 1 |
| Bott, M; Georgi, T; Kabus, A; Wendisch, VF | 1 |
| Lamb, AL; Meneely, KM | 1 |
| Baiga, TJ; Bowman, ME; Koeduka, T; Louie, GV; Noel, JP; Pichersky, E; Spassova, SM; Taylor, JH | 1 |
| Chang, GG; Chou, WY; Hsu, YJ; Kuo, CC; Lin, KY; Lin, SY; Lin, YT | 1 |
| Du, H; Lin, X; Lin, Y; Zeng, Q; Zhai, Z | 1 |
| Fang, YW; Hsieh, JY; Hung, HC; Liu, JH | 1 |
| Dunford, AJ; Girvan, HM; Munro, AW; Scrutton, NS | 1 |
| Heyes, DJ; Menon, BR; Scrutton, NS; Waltho, JP | 1 |
| Cook, PF; Vashishtha, AK; West, AH | 1 |
| Aliverti, A; Bolognesi, M; Canevari, G; Crobu, D; Milani, M; Pandini, V; Vanoni, MA; Zanetti, G | 1 |
| Cai, W; Chen, X; He, JC; Striker, GE; Torreggiani, M; Vlassara, H; Zhu, L | 1 |
| Choudhury, M; Jackson, D; Park, PH; Shukla, SD | 1 |
| Ikeda, M; Kobayashi, R; Mitsuhashi, S; Murata, R; Takeno, S | 1 |
| Almasi, JN; Bushnell, EA; Gauld, JW | 1 |
| Denu, JM; Dittenhafer-Reed, KE; Yu, W | 1 |
| Chung, HW; Tu, SC | 1 |
| Bae, KH; Chung, SJ; Kang, HJ; Kim, EY; Kim, JH; Kim, WK; Lee, SC; Park, SG; Seo, YS | 1 |
| Guo, C; Li, J; Li, W; Myatt, L; Sun, K; Wang, W | 1 |
| Hor, L; Hutton, CA; Perugini, MA; Peverelli, MG | 1 |
| Bommareddy, RR; Chen, Z; Frank, D; Rappert, S; Zeng, AP | 1 |
| Robinson, RM; Rodriguez, PJ; Sobrado, P | 1 |
| Bommareddy, RR; Chen, Z; Rappert, S; Zeng, AP | 1 |
| Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Ji, Q; Jiang, L; Jin, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Li, Y; Lin, R; Lonial, S; Mao, H; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhou, L | 1 |
| French, NS; Maggs, JL; Meng, X; Naisbitt, DJ; Park, BK; Usui, T; Whitaker, P | 1 |
| Binda, C; Keul, ND; Martin Del Campo, JS; Mattevi, A; Robinson, HH; Robinson, RM; Rodriguez, PJ; Sobrado, P | 1 |
| Kim, KJ; Sagong, HY | 1 |
| Abdelwahab, H; Adly, C; El-Sohaimy, S; Robinson, R; Rodriguez, P; Sobrado, P | 1 |
| Devenish, SRA; Goldstone, DC; Grant Pearce, F; Keown, JR; Richards, E; Watkin, SAJ | 1 |
| Feng, Q; Li, W; Liu, L; Ma, L; Shen, X; Sun, X; Wang, J; Yan, Y; Yuan, Q; Zheng, G | 1 |
| Alam, MT; Correia-Melo, C; Haas, R; Herrera-Dominguez, L; Kamrad, S; Méndez-Lucio, O; Miller-Fleming, L; Mülleder, M; Olin-Sandoval, V; Peña Navarro, DA; Ralser, M; Segal, J; Vowinckel, J; Yu, JSL | 1 |
| Feng, C; Li, J; Zheng, H | 1 |
| Chikuma, Y; Hase, T; Kimata-Ariga, Y; Lee, YH; Miyata, M | 1 |
| Arellano, M; Blum, WG; Boggon, TJ; Chen, D; Chen, J; Dong, L; Elf, SE; Famulare, CA; Fan, H; Gao, X; He, C; Le Beau, M; Levine, RL; Li, Y; Lonial, S; Mao, H; Odenike, O; Stock, W; Su, R; Wang, M; Wu, R; Xia, S; Zhang, R; Zhu, AC | 1 |
| Becker, J; Hoffmann, SL; Hutter, M; Jungmann, L; Kohlstedt, M; Poblete-Castro, I; Wittmann, C | 1 |
| Brown, H; Gelin, M; Hoxhaj, G; Kesavan, R; Labesse, G; Lemoff, A; Lionne, C; Mary, C; Mathews, TP; Soflaee, MH; Zacharias, G | 1 |
| Li, L; Li, N; Yu, S; Zhou, J | 1 |
| Cao, G; Chen, B; Ge, F; Jia, K; Jia, S; Lin, J; Lin, X; Ling, M; Wang, M; Wei, W; Yang, M; Zhang, Q | 1 |
| Liu, J; Ou, Y; Rao, ZM; Xu, JZ; Zhang, WG | 1 |
2 review(s) available for lysine and nadp
| Article | Year |
|---|---|
Network rigidity and metabolic engineering in metabolite overproduction.
Topics: Carbon Dioxide; Corynebacterium; Enzymes; Genetic Engineering; Glucose; Lysine; Metabolism; NADP | 1991 |
[Saccharopinuria (a variant form of familial hyperlysinemia)].
Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Humans; Infant, Newborn; Lysine; NADP; Prognosis | 1998 |
139 other study(ies) available for lysine and nadp
| Article | Year |
|---|---|
Mechanisms for the oxidative decarboxylation of isocitrate: implications for control.
Topics: Carboxylic Acids; Decarboxylation; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Lysine; Methionine; Models, Chemical; NAD; NADP; Sulfhydryl Compounds | 1975 |
Identification of the chemical groups involved in the binding of periodate-oxidized NADP+ to 6-phosphogluconate dehydrogenase.
Topics: Binding Sites; Candida; Lysine; NADP; Periodic Acid; Phosphogluconate Dehydrogenase; Protein Binding | 1976 |
A lysyl residue at the NADP binding site of ferredoxin-NADP reductase.
Topics: Adenosine Monophosphate; Binding Sites; Dansyl Compounds; Ferredoxin-NADP Reductase; Ferredoxins; Flavin-Adenine Dinucleotide; Lysine; NAD; NADH, NADPH Oxidoreductases; NADP; Protein Binding; Protein Conformation; Spectrophotometry | 1976 |
Physicochemical evidence for the existence of two pyridoxal 5'-phosphate binding sites on glutamate dehydrogenase and characterization of their functional role.
Topics: Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Guanosine Triphosphate; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Ligands; Liver; Lysine; Molecular Weight; NADP; Protein Conformation; Pyridoxal Phosphate | 1977 |
Comparison of octopine, histopine, lysopine, and octopinic acid synthesizing activities in sunflower crown gall tissues.
Topics: Amino Acids; Arginine; Histidine; Lysine; NAD; NADP; Ornithine; Plant Diseases; Pyruvates; Rhizobium | 1977 |
Modification of Rhodospirillum rubrum ribulose bisphosphate carboxylase with pyridoxal phosphate. 1. Identification of a lysyl residue at the active site.
Topics: Bicarbonates; Binding Sites; Carboxy-Lyases; Chlorides; Hexosephosphates; Lysine; Magnesium; NADP; Pentosephosphates; Pyridoxal Phosphate; Rhodospirillum rubrum; Ribulose-Bisphosphate Carboxylase; Schiff Bases | 1978 |
Affinity labelling of the NADP+-binding site of glucose 6-phosphate dehydrogenase from Candida utilis.
Topics: Affinity Labels; Binding Sites; Candida; Glucosephosphate Dehydrogenase; Kinetics; Lysine; NADP; Oxidation-Reduction; Periodic Acid | 1979 |
Lysine-ketoglutarate reductase in human tissues.
Topics: Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kidney; Kinetics; Liver; Lysine; Myocardium; NADP; Oxidoreductases Acting on CH-NH Group Donors; Skin; Spectrophotometry; Sulfhydryl Compounds; Temperature | 1975 |
Evidence for an essential lysine in glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides.
Topics: Binding Sites; Dinitrophenols; Glucosephosphate Dehydrogenase; Kinetics; Leuconostoc; Lysine; Mathematics; NAD; NADP; Protein Binding; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Time Factors | 1975 |
Pathways and regulation of glutamate synthesis in a Corynebacterium sp. overproducing glutamate.
Topics: Ammonium Sulfate; Cell-Free System; Corynebacterium; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Ketoglutaric Acids; Lysine; NAD; NADP; Nitrates; Soil Microbiology | 1975 |
Subunits asymmetry in the ternary complex of lamb liver 6-phosphogluconate dehydrogenase detected by a NADP analogue.
Topics: Animals; Binding Sites; Cysteine; Gluconates; Liver; Lysine; NADP; Phosphogluconate Dehydrogenase; Protein Conformation; Sheep | 1992 |
Importance of lysine-286 at the NADP site of glutamate dehydrogenase from Salmonella typhimurium.
Topics: Binding Sites; Escherichia coli; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; NADP; Salmonella typhimurium; Structure-Activity Relationship | 1992 |
The role of cytochrome P450 lysine residues in the interaction between cytochrome P450IA1 and NADPH-cytochrome P450 reductase.
Topics: Acetic Anhydrides; Animals; Benzene Derivatives; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 Enzyme System; Hydroxylation; Lysine; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Protein Conformation; Rats; Spectrometry, Fluorescence; Structure-Activity Relationship; Trypsin | 1992 |
Changes in the electron density of the cofactor NADPH on binding to E. coli dihydrofolate reductase.
Topics: Arginine; Computer Simulation; Electrochemistry; Escherichia coli; Lysine; Models, Molecular; Molecular Structure; Mutation; NADP; Quantum Theory; Tetrahydrofolate Dehydrogenase | 1991 |
Identification of Lys116 as the target of N-ethylmaleimide inactivation of ferredoxin:NADP+ oxidoreductase.
Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Dansyl Compounds; Ethylmaleimide; Horses; Lysine; NADP; Oxidation-Reduction; Oxidoreductases; Peptide Mapping; Trypsin | 1991 |
The cosubstrate NADP(H) protects lysine 601 in the porcine NADPH-cytochrome P-450 reductase against pyridoxylation.
Topics: Alkylation; Animals; Binding Sites; Chromatography, High Pressure Liquid; Liver; Lysine; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Pyridoxal Phosphate; Substrate Specificity; Swine | 1990 |
Role of lysine-54 in determining cofactor specificity and binding in human dihydrofolate reductase.
Topics: Amino Acid Sequence; Base Sequence; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oligonucleotide Probes; Recombinant Fusion Proteins; Tetrahydrofolate Dehydrogenase | 1990 |
Phosphorylation inactivates Escherichia coli isocitrate dehydrogenase by preventing isocitrate binding.
Topics: Binding Sites; Escherichia coli; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Lysine; Mutation; NADP; Phosphorylation; Protein Binding; Serine; Templates, Genetic | 1989 |
Affinity labeling of cofactor-binding region of human placental estradiol 17 beta-dehydrogenase by periodate-oxidized NADP+ (o-NADP+).
Topics: 17-Hydroxysteroid Dehydrogenases; Affinity Labels; Binding Sites; Estradiol Dehydrogenases; Humans; Lysine; NADP; Oxidation-Reduction; Periodic Acid; Placenta | 1989 |
Methotrexate analogues. 30. Dihydrofolate reductase inhibition and in vitro tumor cell growth inhibition by N epsilon-(haloacetyl)-L-lysine and N delta-(haloacetyl)-L-ornithine analogues and an acivicin analogue of methotrexate.
Topics: Acetates; Animals; Candida albicans; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Isoxazoles; Leukemia L1210; Lysine; Methotrexate; Mice; NADP; Ornithine; Protein Conformation; Spectrophotometry | 1987 |
Inactivation of carbonyl reductase from human brain by phenylglyoxal and 2,3-butanedione: a comparison with aldehyde reductase and aldose reductase.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aldehyde Reductase; Aldehydes; Arginine; Brain; Butanones; Diacetyl; Humans; Kinetics; Lysine; NADP; Phenylglyoxal; Sugar Alcohol Dehydrogenases; Sulfhydryl Compounds | 1987 |
NBD-Cl modification of essential residues in mitochondrial nicotinamide nucleotide transhydrogenase from bovine heart.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; Kinetics; Lysine; Mitochondria, Heart; NAD; NADH, NADPH Oxidoreductases; NADP; NADP Transhydrogenases; Oxadiazoles; Photochemistry; Spectrometry, Fluorescence; Spectrophotometry; Sulfhydryl Compounds | 1988 |
The NADP+-binding site of ferredoxin-NADP+ reductase. Sequence of the peptide containing the essential lysine residue.
Topics: Amino Acid Sequence; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dansyl Compounds; Enzyme Inhibitors; Ferredoxin-NADP Reductase; Lysine; NADH, NADPH Oxidoreductases; NADP; Peptides; Structure-Activity Relationship | 1985 |
Nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase of Neurospora. I. Isolation, subunits, amino acid composition, sulfhydryl groups, and identification of a lysine residue reactive with pyridoxal phosphate and N-ethylmaleimide.
Topics: Amino Acids; Ammonium Sulfate; Binding Sites; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; Glutamate Dehydrogenase; Lysine; Macromolecular Substances; Mathematics; Molecular Weight; NADP; Neurospora; Peptides; Pyridoxal Phosphate; Sulfhydryl Compounds; Sulfhydryl Reagents; Thermodynamics; Trypsin; Ultracentrifugation | 1973 |
Biosynthesis of slaframine, (1S,6S,8aS)-1-acetoxy-6-aminooctahydroindolizine, a parasympathomimetic alkaloid of fungal origin. I. Pipecolic acid and slaframine biogenesis.
Topics: Acetyl Coenzyme A; Alkaloids; Amines; Carbon Radioisotopes; Cell-Free System; Indolizines; Lysine; Mitosporic Fungi; NADP; Parasympathomimetics; Pipecolic Acids; Tritium | 1973 |
Biosynthesis of slaframine, (1S,6S,8aS)-1-acetoxy-6-aminooctahydroindolizine, a parasympathomimetic alkaloid of fungal origin. II. The origin of pipecolic acid.
Topics: Acetamides; Alkaloids; Amino Acid Isomerases; Carbon Radioisotopes; Chromatography, Ion Exchange; Hydroxylamines; Indolizines; Lysine; Mitosporic Fungi; NADP; Nitrogen Isotopes; Oxidoreductases; Parasympathomimetics; Pipecolic Acids; Piperidines; Pyridines; Stereoisomerism; Tritium | 1973 |
Triphosphopyridine nucleotide specific isocitrate dehydrogenase from Azotobacter vinelandii. Alkylation of a specific methionine residue and amino acid sequence of the peptide containing this residue.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Cysteine; Iodoacetates; Isocitrate Dehydrogenase; Lysine; Malates; Methionine; NADP; Peptide Fragments; Protein Denaturation; Structure-Activity Relationship; Thiocyanates; Tritium; Trypsin; Urea | 1974 |
Biosynthesis and degradation of saccharopine, an intermediate of lysine metabolism.
Topics: Ammonium Chloride; Animals; Carbon Radioisotopes; Cattle; Chromatography, Paper; Electrophoresis; Glutarates; Hydrogen-Ion Concentration; Ketoglutaric Acids; Liver; Lysine; Mitochondria, Liver; NADP; Oxidoreductases | 1973 |
Dihydrodipicolinic acid reductase.
Topics: Amino Acids, Diamino; Binding, Competitive; Chromatography, DEAE-Cellulose; Chromatography, Gel; Escherichia coli; Flavins; Hydrogen-Ion Concentration; Kinetics; Lysine; NAD; NADP; Oxidoreductases; Phthalic Acids; Picolinic Acids; Pimelic Acids; Structure-Activity Relationship; Tritium | 1974 |
Saccharopine dehydrogenase. A kinetic study of coenzyme binding.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Glyceric Acids; Guanine; Hypoxanthines; Kinetics; Lysine; Mathematics; NAD; NADP; Nucleoside Diphosphate Sugars; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Ribonucleotides; Ribose; Saccharomyces cerevisiae; Ultrafiltration | 1974 |
The effect of lysine on gluconeogenesis from lactate in rat hepatocytes.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Female; Gluconeogenesis; Glucose; Glutamates; Lactates; Liver; Lysine; Mitochondria, Liver; NADP; Oxaloacetates; Pyruvate Carboxylase; Pyruvates; Rats | 1974 |
Saccharopine, an intermediate of the aminoadipic acid pathway of lysine biosynthesis. 3. Aminoadipic semialdehyde-glutamate reductase.
Topics: Adipates; Amino Acid Oxidoreductases; Dipeptides; Glutamates; Lysine; NAD; NADP; Saccharomyces | 1966 |
Influence of gonadtrophins on the cholesterol-sidechain cleavage reaction by rat-testis mitochondrial preparations.
Topics: Adrenocorticotropic Hormone; Animals; Caproates; Carbon Isotopes; Cholesterol; Chorionic Gonadotropin; Citrates; Fumarates; Gonadotropins; Humans; Hypophysectomy; In Vitro Techniques; Ketoglutaric Acids; Lysine; Male; Mitochondria; NADP; Pregnenolone; Prolactin; Protein Biosynthesis; Rats; Succinates; Testis; Thyrotropin | 1967 |
Conversion of lysine to saccharopine by human tissues.
Topics: Carbon Isotopes; Chromatography, Ion Exchange; Cold Temperature; Dipeptides; Electrophoresis; Glutarates; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kidney; Liver; Lysine; NADP; Oxidoreductases; Quaternary Ammonium Compounds; Sulfates | 1968 |
Production of antibodies with specificity toward adenosine, uridine, and ribose 5-phosphates.
Topics: Adenine Nucleotides; Animals; Antibody Formation; Antigen-Antibody Reactions; Binding Sites; Coenzymes; Complement Fixation Tests; Flavin-Adenine Dinucleotide; Glutamates; Guanine Nucleotides; Immunochemistry; Lysine; NAD; NADP; Oxidation-Reduction; Pentosephosphates; Polymers; Rabbits; Ribose; Uracil Nucleotides | 1968 |
Multivalent regulation of glutamic dehydrogenases from fungi. Effects of adenylates, guanylates, and acyl coenzyme A derivatives.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Ammonia; Citrates; Citric Acid Cycle; Coenzyme A; Drug Antagonism; Enzyme Activation; Enzyme Induction; Enzyme Repression; Fungi; Glutamate Dehydrogenase; Guanine Nucleotides; Ketoglutaric Acids; Lysine; NADP; Oleic Acids; Palmitic Acids; Pyruvates | 1970 |
The degradation of hydroxy-L-lysine in liver via its phosphate ester.
Topics: Adenosine Triphosphate; Adipates; Aldehydes; Amino Acids; Animals; Esters; Guanine Nucleotides; Liver; Lysine; Male; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Rats; Stereoisomerism | 1970 |
The conversion of L-lysine to saccharopine and alpha-aminoadipate in mouse.
Topics: Adipates; Aldehydes; Amines; Amino Acids; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Dipeptides; In Vitro Techniques; Ketoglutaric Acids; Liver; Lysine; Male; Mice; NAD; NADP; Oxidation-Reduction; Pipecolic Acids; Transaminases | 1971 |
Glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides. Kinetic studies.
Topics: Aldehydes; Chemical Phenomena; Chemistry; Glucosephosphate Dehydrogenase; Hexosephosphates; Hydrogen-Ion Concentration; Isomerism; Kinetics; Leuconostoc; Lysine; NAD; NADP; Picolines; Protein Binding; Pyridoxal Phosphate | 1971 |
Enzyme regulation, lysine pathways and cell wall structures as indicators of major lines of evolution in fungi.
Topics: Ascomycota; Basidiomycota; Biological Evolution; Calcium; Cell Wall; Fungi; Glutamate Dehydrogenase; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Lysine; Magnesium; Myxomycetes; NAD; NADP; Pimelic Acids | 1971 |
Bovine liver glutamate dehydrogenase. Equilibria and kinetics of inactivation by pyridoxal.
Topics: Aldehydes; Animals; Cattle; Chemical Phenomena; Chemistry; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Imines; Kinetics; Liver; Lysine; Mathematics; Models, Biological; Models, Structural; NAD; NADP; Picolines; Protein Binding; Pyridoxal; Pyridoxine; Spectrophotometry | 1971 |
Bovine liver glutamate dehydrogenase. Equilibria and kinetics of imine formation by lysine-97 with pyridoxal 5'-phosphate.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Imines; Kinetics; Liver; Lysine; Mathematics; Models, Biological; Models, Structural; NAD; NADP; Protein Binding; Pyridoxal Phosphate | 1971 |
Lysine biosynthesis in Saccharomyces. Conversion of -aminoadipate into -aminoadipic -semialdehyde.
Topics: Adenosine Triphosphate; Adipates; Aldehydes; Amines; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Lysine; Magnesium; NADP; Phosphorus Isotopes; Saccharomyces; Spectrophotometry | 1971 |
Effect of trinitrophenylation of specific lysyl residues on the catalytic, regulatory, and molecular properties of bovine liver glutamate dehydrogenase.
Topics: Adenosine Diphosphate; Allosteric Regulation; Animals; Catalysis; Cattle; Chromatography, Gel; Enzyme Activation; Glutamate Dehydrogenase; Guanosine Triphosphate; Ketoglutaric Acids; Kinetics; Liver; Lysine; Macromolecular Substances; NAD; NADP; Nitrobenzenes; Rats; Spectrophotometry; Sulfonic Acids; Ultracentrifugation | 1971 |
Degradation of lysine in chicks.
Topics: Aerobiosis; Amino Acid Oxidoreductases; Anaerobiosis; Animal Nutritional Physiological Phenomena; Animals; Arginine; Carbon Dioxide; Carbon Isotopes; Chickens; Dietary Proteins; Dipeptides; Glutarates; Ketoglutaric Acids; Liver; Lysine; Mitochondria, Liver; NADP; Nutritional Requirements; Oxidoreductases; Pipecolic Acids; Species Specificity | 1972 |
Modification of a lysine residue of adrenodoxin reductase, essential for complex formation with adrenodoxin.
Topics: Adrenal Cortex; Adrenodoxin; Animals; Binding Sites; Cattle; Circular Dichroism; Ferredoxin-NADP Reductase; Lysine; NADH Dehydrogenase; NADH, NADPH Oxidoreductases; NADP; Neuraminidase; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship | 1984 |
Selective chemical modification of the active sites of the ketoacyl reductase and enoyl reductase of fatty acid synthetase from lactating rat mammary glands.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Acyl Carrier Protein; Alcohol Oxidoreductases; Animals; Arginine; Binding Sites; Enoyl-(Acyl-Carrier Protein) Reductase (NADPH, B-Specific); Fatty Acid Synthases; Female; Lactation; Lysine; Mammary Glands, Animal; NADP; Oxidoreductases; Phenylglyoxal; Pregnancy; Pyridoxal Phosphate; Rats | 1980 |
Phenol hydroxylase from yeast: a lysyl residue essential for binding of reduced nicotinamide adenine dinucleotide phosphate.
Topics: Amino Acids; Lysine; Mixed Function Oxygenases; NADP; Phenols; Pyridoxal Phosphate; Saccharomyces cerevisiae; Spectrophotometry | 1980 |
Involvement of lysine residue in the nucleotide binding of pigeon liver malic enzyme: modification with affinity label periodate-oxidized NADP.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Affinity Labels; Animals; Binding Sites; Binding, Competitive; Columbidae; Kinetics; Liver; Lysine; Malate Dehydrogenase; NADP; Oxidation-Reduction | 1982 |
Structure and function of mutant Arg44Lys of 4-hydroxybenzoate hydroxylase implications for NADPH binding.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Arginine; Base Sequence; Binding Sites; Catalysis; Lysine; Molecular Sequence Data; Mutation; NADP; Oligodeoxyribonucleotides; Spectrum Analysis; Structure-Activity Relationship | 1995 |
A site-directed mutagenesis study at Lys-113 of NAD(P)H:quinone-acceptor oxidoreductase: an involvement of Lys-113 in the binding of the flavin adenine dinucleotide prosthetic group.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; Escherichia coli; Flavin-Adenine Dinucleotide; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); NADP; Point Mutation; Recombinant Proteins; Vitamin K | 1995 |
Role of lysine residues in the nucleotides binding to bovine liver high-Km aldehyde reductase.
Topics: Aldehyde Reductase; Amino Acid Sequence; Animals; Cattle; Hot Temperature; Liver; Lysine; Molecular Sequence Data; NADP; Nucleotides; Protein Binding; Pyridines; Pyridoxal Phosphate; Trinitrobenzenesulfonic Acid | 1995 |
Essential lysine residue in glutathione reductase: chemical modification by pyridoxal 5'-phosphate.
Topics: Adenosine Monophosphate; Binding Sites; Borohydrides; Glutathione; Glutathione Reductase; Lysine; NAD; NADP; Pyridoxal Phosphate; Schiff Bases; Spectrometry, Fluorescence; Yeasts | 1995 |
An essential lysyl residue (Lys208) in the substrate-binding site of porcine FAD-containing monooxygenase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Female; Lysine; Microsomes, Liver; Molecular Sequence Data; NADP; Oxygenases; Peptide Fragments; Peptide Mapping; Pyridoxal Phosphate; Substrate Specificity; Swine | 1995 |
Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110.
Topics: Aldehyde Reductase; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; DNA Primers; Female; Histidine; Humans; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Placenta; Pregnancy; Protein Conformation; Recombinant Proteins; Tyrosine | 1993 |
Chemical modification of arginine and lysine residues in coenzyme-binding domain of carbonyl reductase from rabbit kidney: indomethacin affords a significant protection against inactivation of the enzyme by phenylglyoxal.
Topics: Alcohol Oxidoreductases; Animals; Arginine; Enzyme Activation; Indomethacin; Kidney; Lysine; NADP; Phenylglyoxal; Rabbits; Trinitrobenzenesulfonic Acid | 1994 |
FAD and substrate analogs as probes for lysine N6-hydroxylase from Escherichia coli EN 222.
Topics: Amino Acid Sequence; Binding Sites; Escherichia coli; Flavin-Adenine Dinucleotide; Lysine; Molecular Sequence Data; NADP; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Structure-Activity Relationship; Substrate Specificity | 1993 |
Inactivation of an NADPH-dependent succinic semialdehyde reductase by o-phthalaldehyde.
Topics: Animals; Binding Sites; Brain; Cattle; Cross-Linking Reagents; Cysteine; Enzyme Inhibitors; Hydroxybutyrate Dehydrogenase; Indoles; Kinetics; Lysine; NADP; o-Phthalaldehyde | 1996 |
Mutational analysis of photosystem I polypeptides. Role of PsaD and the lysyl 106 residue in the reductase activity of the photosystem I.
Topics: Base Sequence; Electron Spin Resonance Spectroscopy; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Oxidoreductases; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Plant Proteins; Structure-Activity Relationship | 1996 |
Crystal structures of a ferredoxin: NADP+ reductase and of a complex with NADP+.
Topics: Anabaena; Arginine; Binding Sites; Crystallography, X-Ray; Ferredoxin-NADP Reductase; Glutamine; Lysine; Models, Structural; NADP; Protein Conformation; Protein Folding; Protein Structure, Secondary | 1996 |
Evidence for flavin movement in the function of p-hydroxybenzoate hydroxylase from studies of the mutant Arg220Lys.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Arginine; Binding Sites; Catalysis; Flavin-Adenine Dinucleotide; Flavins; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Mutation; NADP; Oxidation-Reduction; Parabens; Protein Conformation; Spectrophotometry | 1996 |
Involvement of two basic residues (Lys-270 and Arg-276) of human liver 3 alpha-hydroxysteroid dehydrogenase in NADP(H) binding and activation by sulphobromophthalein: site-directed mutagenesis and kinetic analysis.
Topics: 3-Hydroxysteroid Dehydrogenases; Arginine; Binding Sites; Enzyme Activation; Humans; Kinetics; Liver; Lysine; Mutagenesis, Site-Directed; NADP; Sulfobromophthalein | 1997 |
Modification of an essential amino group of glutathione reductase from yeast by pyridoxal 5'-phosphate.
Topics: Crystallography, X-Ray; Enzyme Inhibitors; Glutathione Disulfide; Glutathione Reductase; Hydrogen-Ion Concentration; Kinetics; Lysine; NADP; Pyridoxal Phosphate; Saccharomyces cerevisiae; Structure-Activity Relationship | 1997 |
Effect of selective cysteine --> alanine replacements on the catalytic functions of lysine: N6-hydroxylase.
Topics: 2,6-Dichloroindophenol; Alanine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyanogen Bromide; Cysteine; Dithionitrobenzoic Acid; Flavoproteins; Iodoacetates; Iodoacetic Acid; Lysine; Mass Spectrometry; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Peptide Fragments; Protein Conformation; Recombinant Proteins; Sequence Analysis; Trypsin | 1997 |
Lys42 and Ser42 variants of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens reveal that Arg42 is essential for NADPH binding.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Base Sequence; Binding Sites; Crystallography, X-Ray; Escherichia coli; Gene Expression; Genetic Variation; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADP; Oligodeoxyribonucleotides; Protein Conformation; Pseudomonas fluorescens; Recombinant Proteins; Serine; Spectrophotometry | 1998 |
Complex formation between Azotobacter vinelandii ferredoxin I and its physiological electron donor NADPH-ferredoxin reductase.
Topics: Amino Acid Sequence; Anabaena; Azotobacter vinelandii; Circular Dichroism; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ferredoxin-NADP Reductase; Ferredoxins; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; NADP; Protein Conformation; Pseudomonas aeruginosa; Static Electricity | 1999 |
Site-directed mutagenesis of charged and potentially proton-carrying residues in the beta subunit of the proton-translocating nicotinamide nucleotide transhydrogenase from Escherichia coli. Characterization of the beta H91, beta D392, and beta K424 mutant
Topics: Aspartic Acid; Biological Transport; Catalysis; Conserved Sequence; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Lysine; Magnesium Chloride; Mutagenesis, Site-Directed; NADP; NADP Transhydrogenases; Proton Pumps; Recombinant Proteins; Sodium Chloride | 1999 |
The cysteine-proximal aspartates in the Fx-binding niche of photosystem I. Effect of alanine and lysine replacements on photoautotrophic growth, electron transfer rates, single-turnover flash efficiency, and EPR spectral properties.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Cyanobacteria; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Kinetics; Lysine; Membrane Proteins; Mutagenesis, Site-Directed; NADP; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Structure-Activity Relationship | 1999 |
Carbon monoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb.
Topics: Animals; Biliverdine; Carbon Monoxide; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Kidney; Lysine; Male; NADP; Patch-Clamp Techniques; Porphyrins; Potassium Channels; Rats; Rats, Sprague-Dawley; RNA | 1999 |
Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5.
Topics: 2-Aminoadipic Acid; Acyl Carrier Protein; Aldehyde Oxidoreductases; Carbocysteine; Escherichia coli; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; NADP; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Sulfur Radioisotopes | 1999 |
Lysine 219 participates in NADPH specificity in a flavin-containing monooxygenase from Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cysteine; Escherichia coli; Flavin-Adenine Dinucleotide; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Oxygenases; Phosphates; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Alignment; Substrate Specificity | 1999 |
Lysine residues 162 and 340 are involved in the catalysis and coenzyme binding of NADP(+)-dependent malic enzyme from pigeon.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Catalysis; Cloning, Molecular; Columbidae; Conserved Sequence; Humans; Kinetics; Liver; Lysine; Malate Dehydrogenase; Malates; Manganese; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2000 |
Crystal structure of saccharopine reductase from Magnaporthe grisea, an enzyme of the alpha-aminoadipate pathway of lysine biosynthesis.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Fungal Proteins; Hydrogen Bonding; Ligands; Lysine; Magnaporthe; Models, Molecular; Molecular Sequence Data; NADP; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharopine Dehydrogenases | 2000 |
Delineation of the roles of amino acids involved in the catalytic functions of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase.
Topics: Arginine; Binding Sites; Catalysis; Conserved Sequence; Dimerization; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Glutamine; Kinetics; Leuconostoc; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Proline; Thermodynamics | 2000 |
Coenzyme specificity in aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Binding Sites; Catalytic Domain; Coenzymes; Glutamic Acid; In Vitro Techniques; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADP; Protein Conformation; Protein Denaturation; Rats | 2001 |
Coenzyme specificity of human monomeric carbonyl reductase: contribution of Lys-15, Ala-37 and Arg-38.
Topics: Alanine; Alcohol Oxidoreductases; Arginine; Binding Sites; Coenzymes; Escherichia coli; Humans; In Vitro Techniques; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; NADP; Recombinant Proteins | 2001 |
Tyr275 and Lys279 stabilize NADPH within the catalytic site of NADPH:protochlorophyllide oxidoreductase and are involved in the formation of the enzyme photoactive state.
Topics: Amino Acid Substitution; Binding Sites; Catalytic Domain; Enzyme Activation; Enzyme Stability; Freezing; Kinetics; Lysine; Mutagenesis, Site-Directed; NADP; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Photochemistry; Pisum sativum; Protein Denaturation; Protochlorophyllide; Rhodobacter capsulatus; Spectrometry, Fluorescence; Substrate Specificity; Temperature; Tyrosine | 2001 |
Inhibition of camel lens zeta-crystallin by aspirin and aspirin-like analgesics.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Binding Sites; Binding, Competitive; Camelus; Crystallins; Ibuprofen; In Vitro Techniques; Kinetics; Lysine; NADP; Phenanthrenes; Pyridoxal Phosphate | 2002 |
Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.
Topics: Adenosylhomocysteinase; Animals; Apoenzymes; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Cattle; Circular Dichroism; Crystallography, X-Ray; DNA, Complementary; Escherichia coli; Holoenzymes; Hydrolases; Hydrolysis; Kinetics; Liver; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Protein Binding; Rats; Time Factors; Ultraviolet Rays | 2002 |
Identification of lysine-78 as an essential residue in the Saccharomyces cerevisiae xylose reductase.
Topics: Aldehyde Reductase; Amino Acid Sequence; Catalytic Domain; Enzyme Activation; Fermentation; Lysine; Molecular Sequence Data; NADP; Pentose Phosphate Pathway; Protein Binding; Recombinant Proteins; Saccharomyces cerevisiae | 2002 |
Nitrate regulation of alpha-aminoadipate reductase formation and lysine inhibition of its activity in Penicillium chrysogenum and Acremonium chrysogenum.
Topics: Acremonium; Aldehyde Oxidoreductases; Feedback; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; NADP; Nitrates; Penicillium chrysogenum | 2002 |
Site-directed mutagenesis of Tyr-189 and Lys-193 in NADPH: protochlorophyllide oxidoreductase from Synechocystis.
Topics: Amino Acid Substitution; Base Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; Cyanobacteria; DNA Primers; Escherichia coli; Kinetics; Lysine; Mutagenesis, Site-Directed; NADP; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Tyrosine | 2002 |
Genealogy profiling through strain improvement by using metabolic network analysis: metabolic flux genealogy of several generations of lysine-producing corynebacteria.
Topics: Citric Acid Cycle; Corynebacterium; Genealogy and Heraldry; Glucose-6-Phosphate; Glycolysis; Glyoxylates; Lysine; Mass Spectrometry; NADP; Pentose Phosphate Pathway; Pyruvic Acid | 2002 |
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea | 2002 |
Site-directed mutational analysis of the novel catalytic domains of alpha-aminoadipate reductase (Lys2p) from Candida albicans.
Topics: Adenosine Triphosphate; Aldehyde Oxidoreductases; Amino Acid Sequence; Candida albicans; Catalytic Domain; Escherichia coli; Genotype; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Plasmids; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid | 2003 |
Crystal structure of the vertebrate NADP(H)-dependent alcohol dehydrogenase (ADH8).
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Binding Sites; Crystallography, X-Ray; Lysine; Models, Molecular; NADP; Protein Conformation; Protons; Ranidae | 2003 |
Complete reversal of coenzyme specificity by concerted mutation of three consecutive residues in alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Animals; Binding Sites; Catalysis; Computer Simulation; Deuterium; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NADP; Protein Binding; Ranidae; Time Factors | 2003 |
Metabolic phenotype of phosphoglucose isomerase mutants of Corynebacterium glutamicum.
Topics: Cell Division; Corynebacterium; Gene Expression Regulation, Bacterial; Genetic Enhancement; Glucose-6-Phosphate Isomerase; Lysine; Mutagenesis, Site-Directed; Mutation; NADP; Oxygen Consumption; Phenotype; Protein Engineering; Recombinant Proteins; Structure-Activity Relationship | 2003 |
EFFECT OF ENVIRONMENTAL CONDITIONS ON THE NADP-SPECIFIC GLUTAMIC ACID DEHYDROGENASE IN NEUROSPORA CRASSA.
Topics: Amino Acid Oxidoreductases; Ammonium Compounds; Caseins; Glutamates; Glycine; Lysine; NADP; Neurospora; Neurospora crassa; Pharmacology; Proteins; Quaternary Ammonium Compounds; Research; Serine | 1963 |
A positive charge at position 33 of thioredoxin primarily affects its interaction with other proteins but not redox potential.
Topics: Amino Acid Substitution; Bacteriophage T3; Bacteriophage T7; Chromatography, High Pressure Liquid; Circular Dichroism; Disulfides; Escherichia coli; Escherichia coli Proteins; Glycine; Inovirus; Insulin; Kinetics; Lysine; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Spectrometry, Fluorescence; Thioredoxins | 2004 |
Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases.
Topics: Amino Acid Sequence; Arginine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oxygenases; Protein Binding; Sequence Alignment | 2004 |
Role of Lys-32 residues in R67 dihydrofolate reductase probed by asymmetric mutations.
Topics: Binding Sites; Catalysis; Circular Dichroism; Dimerization; Dose-Response Relationship, Drug; Escherichia coli; Hydrogen-Ion Concentration; Ions; Kinetics; Ligands; Lysine; Models, Biological; Models, Molecular; Mutation; NADP; Protein Binding; Protein Conformation; Salts; Spectrometry, Fluorescence; Temperature; Tetrahydrofolate Dehydrogenase | 2004 |
The putative malate/lactate dehydrogenase from Pseudomonas putida is an NADPH-dependent delta1-piperideine-2-carboxylate/delta1-pyrroline-2-carboxylate reductase involved in the catabolism of D-lysine and D-proline.
Topics: Bacterial Proteins; Chromatography, High Pressure Liquid; Coenzymes; Evolution, Molecular; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lysine; Malate Dehydrogenase; NADP; Pipecolic Acids; Proline; Pseudomonas putida; Pyrroline Carboxylate Reductases; Substrate Specificity; Temperature | 2005 |
Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and NADP+.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Arginine; Candida; Coenzymes; Crystallography, X-Ray; Kinetics; Lysine; NAD; NADP; Protein Conformation | 2005 |
Crystal structure of a novel shikimate dehydrogenase from Haemophilus influenzae.
Topics: Alcohol Oxidoreductases; Asparagine; Bayes Theorem; Catalysis; Circular Dichroism; Cloning, Molecular; Crystallography, X-Ray; Haemophilus influenzae; Herbicides; Hydrogen-Ion Concentration; Ions; Kinetics; Lysine; Models, Molecular; Mutagenesis; Mutagenesis, Site-Directed; NAD; NADP; Oxygen; Phylogeny; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Temperature | 2005 |
Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.
Topics: Acetylcysteine; Aldehydes; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 Enzyme System; Glutathione; Humans; Liver; Lung; Lysine; NADP; Pyrroles; Rabbits; Spectrometry, Mass, Electrospray Ionization; Terpenes | 2005 |
Substrate recognition by the human fatty-acid synthase.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Allosteric Site; Antineoplastic Agents; Binding Sites; DNA Primers; Fatty Acid Desaturases; Fatty Acid Synthases; Humans; Kinetics; Lysine; Models, Chemical; Mutagenesis; Mutation; NADP; Protein Binding; Pyridoxal Phosphate; Spectrometry, Fluorescence; Substrate Specificity | 2005 |
Thr373, Asp375, and Lys260 are in the coenzyme site of porcine NADP-dependent isocitrate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Isocitrate Dehydrogenase; Kinetics; Lysine; Mitochondria, Heart; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Protein Structure, Secondary; Recombinant Proteins; Swine; Threonine | 2006 |
Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362.
Topics: Adenosine Triphosphate; Allosteric Site; Catalysis; Fumarates; Glutamine; Humans; Kinetics; Lysine; Malate Dehydrogenase; Mitochondria; NADP; Protein Binding; Substrate Specificity; Thermodynamics | 2006 |
Heterologous expression, purification, and characterization of an l-ornithine N(5)-hydroxylase involved in pyoverdine siderophore biosynthesis in Pseudomonas aeruginosa.
Topics: Amino Acids, Neutral; Aminobutyrates; Cloning, Molecular; Enzyme Inhibitors; Enzyme Stability; Escherichia coli; Flavin-Adenine Dinucleotide; Homoserine; Hydrogen-Ion Concentration; Hydroxylamine; Lysine; Mixed Function Oxygenases; NADP; Oligopeptides; Ornithine; Oxidation-Reduction; Pseudomonas aeruginosa; Recombinant Proteins; Siderophores; Substrate Specificity | 2006 |
Identification of the last unknown genes in the fermentation pathway of lysine.
Topics: Amino Acid Oxidoreductases; Ammonia-Lyases; Bacteria; Base Sequence; Fermentation; Genes, Bacterial; Lysine; Molecular Sequence Data; Multigene Family; NADP; Oxo-Acid-Lyases | 2007 |
Expression of the Escherichia coli pntAB genes encoding a membrane-bound transhydrogenase in Corynebacterium glutamicum improves L-lysine formation.
Topics: Biotechnology; Cell Membrane; Corynebacterium glutamicum; Culture Media; Escherichia coli; Escherichia coli Proteins; Lysine; NADP; NADP Transhydrogenases | 2007 |
Biochemical characterization of a flavin adenine dinucleotide-dependent monooxygenase, ornithine hydroxylase from Pseudomonas aeruginosa, suggests a novel reaction mechanism.
Topics: Animals; Chlorides; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Lysine; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oligopeptides; Ornithine; Oxidation-Reduction; Parabens; Pseudomonas aeruginosa; Pseudomonas fluorescens; Schizosaccharomyces; Siderophores; Solubility; Substrate Specificity; Swine | 2007 |
Structure and reaction mechanism of basil eugenol synthase.
Topics: Benzoquinones; Binding Sites; Binding, Competitive; Catalysis; Crystallography, X-Ray; Eugenol; Hydrogen Bonding; Isoflavones; Lysine; Models, Chemical; Molecular Conformation; NADP; Ocimum basilicum; Oxidoreductases Acting on CH-CH Group Donors; UDPglucose 4-Epimerase | 2007 |
The roles of Tyr(91) and Lys(162) in general acid-base catalysis in the pigeon NADP+-dependent malic enzyme.
Topics: Acids; Alkalies; Catalysis; Circular Dichroism; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Lysine; Malate Dehydrogenase; Molecular Structure; Mutation; NADP; Oxidation-Reduction; Recombinant Proteins; Substrate Specificity; Tyrosine | 2008 |
[Mutational research on the role of lysine 21 in the Pichia stipitis xylose reductase].
Topics: Aldehyde Reductase; Amino Acid Substitution; Coenzymes; Escherichia coli; Ethanol; Lysine; Mutagenesis, Site-Directed; NAD; NADP; Pichia; Recombinant Proteins; Recombination, Genetic; Xylose | 2008 |
Dual roles of Lys(57) at the dimer interface of human mitochondrial NAD(P)+-dependent malic enzyme.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Fumarates; Humans; Hydrogen Bonding; Kinetics; Lysine; Malate Dehydrogenase; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Protein Multimerization; Protein Structure, Quaternary; Sequence Homology, Amino Acid | 2009 |
Probing the molecular determinants of coenzyme selectivity in the P450 BM3 FAD/NADPH domain.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cytochrome P-450 Enzyme System; Flavin-Adenine Dinucleotide; Kinetics; Lysine; Molecular Sequence Data; NADP; NADPH-Ferrihemoprotein Reductase; Protein Structure, Tertiary; Sequence Alignment; Serine | 2009 |
Cryogenic and laser photoexcitation studies identify multiple roles for active site residues in the light-driven enzyme protochlorophyllide oxidoreductase.
Topics: Catalytic Domain; Cold Temperature; Fluorescence; Kinetics; Lasers; Light; Lysine; Mutagenesis; NADP; Oxidoreductases Acting on CH-CH Group Donors; Photochemical Processes; Protein Structure, Tertiary; Protons; Synechococcus; Tyrosine | 2009 |
Chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae.
Topics: Deuterium Exchange Measurement; Hydrogen-Ion Concentration; Kinetics; Lysine; NADP; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Saccharopine Dehydrogenases; Solvents | 2009 |
Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis.
Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Ferredoxin-NADP Reductase; Histidine; Kinetics; Lysine; NADP; Niacinamide; Plasmodium falciparum; Protein Binding; Protein Subunits; Substrate Specificity | 2009 |
AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.
Topics: Active Transport, Cell Nucleus; Age Factors; Animals; Cell Line; Endothelial Cells; ErbB Receptors; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADP; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphorylation; Protein Kinase C-delta; Protein Subunits; Pyruvaldehyde; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; Signal Transduction; Time Factors; Transcription Factor RelA; Transfection; Vascular Diseases | 2010 |
Evidence for the role of oxidative stress in the acetylation of histone H3 by ethanol in rat hepatocytes.
Topics: Acetylation; Acetylcysteine; Alcohol Dehydrogenase; Animals; Antioxidants; Cells, Cultured; Ethanol; Free Radical Scavengers; Glutathione; Hepatocytes; Histones; Hydrogen Peroxide; Lysine; Male; Mitochondria, Liver; NADP; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger | 2010 |
Engineering of Corynebacterium glutamicum with an NADPH-generating glycolytic pathway for L-lysine production.
Topics: Corynebacterium glutamicum; DNA, Bacterial; DNA, Recombinant; Gene Expression Regulation, Bacterial; Genetic Engineering; Glucose; Glyceraldehyde 3-Phosphate; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Glyceric Acids; Glycolysis; Lysine; NADP | 2010 |
A QM/MM-based computational investigation on the catalytic mechanism of saccharopine reductase.
Topics: 2-Aminoadipic Acid; Catalysis; Glutamic Acid; Lysine; Magnaporthe; NADP; Saccharopine Dehydrogenases | 2011 |
SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status.
Topics: Animals; Caloric Restriction; Fibroblasts; Gene Expression Regulation; Glutathione; HEK293 Cells; Humans; Isocitrate Dehydrogenase; Lysine; Mice; Mitochondria; Models, Biological; NADP; Oxidation-Reduction; Oxidative Stress; Sirtuin 3; Sirtuins | 2012 |
Structure-function relationship of Vibrio harveyi NADPH-flavin oxidoreductase FRP: essential residues Lys167 and Arg15 for NADPH binding.
Topics: Amino Acid Sequence; Anaerobiosis; Arginine; Deuterium; FMN Reductase; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Oxidation-Reduction; Protein Binding; Protein Conformation; Structure-Activity Relationship; Substrate Specificity; Vibrio | 2012 |
Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity.
Topics: 3T3-L1 Cells; Acetylation; Adipocytes; Adipogenesis; Animals; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Intracellular Space; Lysine; Malate Dehydrogenase; Mice; Mutagenesis, Site-Directed; Mutation; NADP | 2012 |
Involvement of GR and p300 in the induction of H6PD by cortisol in human amnion fibroblasts.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Amnion; Carbohydrate Dehydrogenases; E1A-Associated p300 Protein; Extraembryonic Membranes; Fibroblasts; Glucocorticoids; Histones; Humans; Hydrocortisone; Lysine; Mifepristone; NADP; Promoter Regions, Genetic; Protein Binding; Receptors, Glucocorticoid; RNA, Small Interfering | 2012 |
A new robust kinetic assay for DAP epimerase activity.
Topics: Amino Acid Isomerases; Amino Acid Oxidoreductases; Bacterial Proteins; Carboxy-Lyases; Corynebacterium glutamicum; Diaminopimelic Acid; Enzyme Assays; Escherichia coli; Escherichia coli Proteins; Kinetics; Lysine; NADP; Recombinant Proteins; Reproducibility of Results | 2013 |
Deregulation of feedback inhibition of phosphoenolpyruvate carboxylase for improved lysine production in Corynebacterium glutamicum.
Topics: Aspartic Acid; Carbon Isotopes; Corynebacterium glutamicum; Enzyme Inhibitors; Feedback; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Isotope Labeling; Lysine; Malates; Metabolic Engineering; Metabolic Flux Analysis; Mutant Proteins; NADP; Phosphoenolpyruvate Carboxylase; Point Mutation | 2014 |
Mechanistic studies on the flavin-dependent N⁶-lysine monooxygenase MbsG reveal an unusual control for catalysis.
Topics: Bacterial Proteins; Biocatalysis; Dinitrocresols; Flavins; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lysine; Mixed Function Oxygenases; Mycobacterium smegmatis; NADP; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Superoxides | 2014 |
A de novo NADPH generation pathway for improving lysine production of Corynebacterium glutamicum by rational design of the coenzyme specificity of glyceraldehyde 3-phosphate dehydrogenase.
Topics: Corynebacterium glutamicum; Genetic Enhancement; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Lysine; Metabolic Engineering; NADP; Signal Transduction | 2014 |
Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.
Topics: Acetyl-CoA C-Acetyltransferase; Acetylation; Animals; Cell Line, Tumor; Dihydrolipoyllysine-Residue Acetyltransferase; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Leukemia; Lung Neoplasms; Lysine; Mice; NADP; Neoplasms, Experimental; Phosphogluconate Dehydrogenase; Protein Binding; Protein Multimerization | 2014 |
Auto-oxidation of Isoniazid Leads to Isonicotinic-Lysine Adducts on Human Serum Albumin.
Topics: Adult; Aged, 80 and over; Female; Humans; Isoniazid; Lysine; Male; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Protein Binding; Serum Albumin | 2015 |
An unprecedented NADPH domain conformation in lysine monooxygenase NbtG provides insights into uncoupling of oxygen consumption from substrate hydroxylation.
Topics: Bacterial Proteins; Crystallography, X-Ray; Flavin-Adenine Dinucleotide; Hydroxylation; Lysine; Mixed Function Oxygenases; NADP; Nocardia; Oxygen Consumption; Protein Structure, Tertiary | 2015 |
Structural Insight into Dihydrodipicolinate Reductase from Corybebacterium glutamicum for Lysine Biosynthesis.
Topics: Amino Acid Sequence; Binding Sites; Biocatalysis; Corynebacterium glutamicum; Crystallography, X-Ray; Dihydrodipicolinate Reductase; Kinetics; Lysine; Models, Molecular; Mycobacterium tuberculosis; NAD; NADP; Oxidoreductases; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity | 2016 |
Identification of structural determinants of NAD(P)H selectivity and lysine binding in lysine N(6)-monooxygenase.
Topics: Amino Acids; Bacterial Proteins; Catalysis; Flavins; Hydrogen Peroxide; Hydroxylation; Kinetics; Lysine; Mixed Function Oxygenases; Molecular Conformation; Mutation; NAD; NADP; Nocardia; Oxygen; Protein Binding | 2016 |
Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly.
Topics: Amino Acid Motifs; Arabidopsis; Bacterial Proteins; Binding Sites; Coenzymes; Crystallography, X-Ray; Dihydrodipicolinate Reductase; Gene Expression; Kinetics; Lysine; Models, Molecular; NAD; NADP; Neisseria meningitidis; Picolinic Acids; Plant Proteins; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins; Selaginellaceae; Species Specificity; Substrate Specificity; Vitis | 2018 |
Targeting metabolic driving and intermediate influx in lysine catabolism for high-level glutarate production.
Topics: Biosynthetic Pathways; Escherichia coli; Glutamic Acid; Glutarates; Lysine; Metabolic Engineering; NADP | 2019 |
Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism.
Topics: Antioxidants; Antiporters; Cadaverine; Glutamine; Glutathione; Lysine; NADP; Organic Cation Transport Proteins; Ornithine Decarboxylase; Oxidants; Polyamines; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2019 |
Heat shock protein 90 enhances the electron transfer between the FMN and heme cofactors in neuronal nitric oxide synthase.
Topics: Animals; Aspartic Acid; Binding Sites; Cloning, Molecular; Electrons; Escherichia coli; Ficoll; Flavin Mononucleotide; Gene Expression; Genetic Vectors; Heme; HSP90 Heat-Shock Proteins; Humans; Lysine; Molecular Docking Simulation; Mutation; NADP; Nitric Oxide Synthase Type I; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Rats; Recombinant Proteins; Static Electricity | 2020 |
Molecular mechanism of negative cooperativity of ferredoxin-NADP+ reductase by ferredoxin and NADP(H): involvement of a salt bridge between Asp60 of ferredoxin and Lys33 of FNR.
Topics: Ferredoxin-NADP Reductase; Ferredoxins; Lysine; Mutation; NADP; Salts | 2021 |
Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.
Topics: Acetyl-CoA C-Acetyltransferase; Acetylation; Animals; Antineoplastic Agents; Female; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Leukemia, Myeloid, Acute; Lysine; Male; Mice; Mice, Inbred NOD; Mutation; NADP; Nuclear Proteins; Phosphorylation; Polymorphism, Single Nucleotide; Primary Cell Culture; Protein Binding; Protein Processing, Post-Translational; Protein-Tyrosine Kinases | 2021 |
Cascaded valorization of brown seaweed to produce l-lysine and value-added products using Corynebacterium glutamicum streamlined by systems metabolic engineering.
Topics: Corynebacterium glutamicum; Humans; Lysine; Metabolic Engineering; NADP; Seaweed | 2021 |
Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation.
Topics: Acetylation; Catalytic Domain; Humans; Lysine; Mitochondrial Proteins; NAD; NADP; Phosphotransferases (Alcohol Group Acceptor); Proline | 2022 |
Dual-channel glycolysis balances cofactor supply for l-homoserine biosynthesis in Corynebacterium glutamicum.
Topics: Corynebacterium glutamicum; Glycolysis; Homoserine; Lysine; Metabolic Engineering; NAD; NADP | 2023 |
cKMT1 is a New Lysine Methyltransferase That Methylates the Ferredoxin-NADP(+) Oxidoreductase and Regulates Energy Transfer in Cyanobacteria.
Topics: Cyanobacteria; Energy Transfer; Ferredoxin-NADP Reductase; Ferredoxins; Lysine; Methyltransferases; NADP; Synechocystis | 2023 |
L-lysine production by systems metabolic engineering of an NADPH auto-regulated Corynebacterium glutamicum.
Topics: Carbon Cycle; Corynebacterium glutamicum; Lysine; Metabolic Engineering; NADP | 2023 |