lysine has been researched along with n(6)-carboxymethyllysine in 771 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (0.39) | 18.7374 |
| 1990's | 91 (11.80) | 18.2507 |
| 2000's | 290 (37.61) | 29.6817 |
| 2010's | 318 (41.25) | 24.3611 |
| 2020's | 69 (8.95) | 2.80 |
| Authors | Studies |
|---|---|
| Höger, H; Lubec, B; Lubec, G; Szalay, S; Weninger, M; Xi, Z | 1 |
| Feather, MS; Ortwerth, BJ; Prabhakaram, M; Shin, DB; Slight, SH | 1 |
| Sakurai, T; Takanashi, M; Tsuchiya, S | 1 |
| Baynes, JW; Dunn, JA; Lyons, TJ; McCance, DR; Thorpe, SR | 1 |
| Baynes, JW; Dunn, JA; Knecht, KJ; Lyons, TJ; McCance, DR; McFarland, KF; Thorpe, SR | 1 |
| Bailie, KE; Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ | 1 |
| Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ; Silvestri, G | 1 |
| Ahmed, MU; Baynes, JW; Dunn, JA; Murtiashaw, MH; Richardson, JM; Thorpe, SR; Walla, MD | 1 |
| Baynes, JW; Dunn, JA; Patrick, JS; Thorpe, SR | 1 |
| Ah-Sing, E; Gould, BJ; Stace, BC; Walsh, DP; Wright, J | 1 |
| Ahmed, MU; Baynes, JW; Thorpe, SR | 1 |
| Kelly, FJ; Lubec, G | 1 |
| Erbersdobler, HF; Hartkopf, J | 2 |
| Baynes, JW; Thorpe, SR; Wells-Knecht, MC | 1 |
| Baynes, JW; Bell-Farrow, AD; Cefalu, WT; Fu, MX; Sonntag, WE; Thorpe, SR; Wang, ZQ | 1 |
| Baynes, JW; Bichler, J; Reddy, S; Thorpe, SR; Wells-Knecht, KJ | 1 |
| Glomb, MA; Monnier, VM | 1 |
| Baynes, JW; Litchfield, JE; Thorpe, SR; Wells-Knecht, KJ; Zyzak, DV | 1 |
| Khaidar, A; Lubec, B; Lubec, G; Marx, M | 1 |
| Höger, H; Lubec, B; Lubec, G; Radner, W; Salzer, H | 1 |
| Baynes, JW; Blackledge, JA; Fu, MX; Lyons, TJ; Thorpe, SR; Wells-Knecht, KJ | 1 |
| Bailie, KE; Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ; McCance, DR; Thorpe, SR | 1 |
| Baynes, JW; Fu, MX; Jenkins, AJ; Lyons, TJ; Requena, JR; Thorpe, SR | 1 |
| Araki, T; Higashi, T; Horiuchi, S; Ikeda, K; Jinnouchi, Y; Sano, H; Ueda, S; Yoshida, M | 1 |
| Kato, Y; Osawa, T; Tokunaga, K | 1 |
| Katsuzaki, T; Kondo, T; Miyazaki, T; Niwa, T; Sato, M; Takei, Y; Tatemichi, N; Tomoo, T | 1 |
| Horiuchi, S; Kimura, T | 1 |
| Horiuchi, S; Ikeda, K; Kimura, T; Miyakawa, T; Miyata, T; Sobue, G; Takamatsu, J | 1 |
| Nerlich, AG; Schleicher, ED; Wagner, E | 1 |
| Bailey, AJ; Paul, RG | 1 |
| Ahmed, MU; Baynes, JW; Brinkmann, E; Litchfield, JE; Reddy, S; Thorpe, SR; Wells-Knecht, KJ; Wells-Knecht, MC; Zyzak, DV | 1 |
| Ahmed, MU; Fu, MX; Jenkins, AJ; Lyons, TJ; Requena, JR; Thorpe, SR | 1 |
| Cai, Z; Horie, K; Iida, Y; Kurokawa, K; Maeda, K; Miyata, T; van Ypersele de Strihou, C; Wada, Y; Yasuda, Y | 1 |
| Horiuchi, S; Ikeda, K; Kayashima, K; Mizutari, K; Ono, T | 1 |
| Araki, T; Higashi, T; Horiuchi, S; Ikeda, K; Jinnouchi, Y; Nagai, R; Sano, H | 1 |
| Aufderheide, AC; Lubec, G; Stocchi, V; Teschler-Nicola, M; Zimmerman, MR | 1 |
| Ahmed, MU; Baynes, JW; Brinkmann Frye, E; Degenhardt, TP; Thorpe, SR | 1 |
| Ahmed, MU; Baynes, JW; Degenhardt, TP; Fountain, CW; Jenkins, AJ; Lyons, TJ; Perez, C; Reddy, S; Requena, JR; Thorpe, SR | 1 |
| Horie, K; Kurokawa, K; Maeda, K; Miyata, T; Sobue, G; Takeda, A; Yasuda, T; Yasuda, Y | 1 |
| Horiuchi, S; Ikeda, K; Inomuta, H; Ishibashi, T; Murata, T; Nagai, R | 1 |
| Katsuzaki, T; Niwa, T; Takei, Y; Tatemichi, N | 1 |
| Baynes, JW; Lyons, TJ; McCance, DR; Thorpe, SR; Wells-Knecht, MC | 1 |
| Baynes, JW; Degenhardt, TP; Diamandis, EP; Grass, L; Reddy, S; Thorpe, SR | 1 |
| Horie, K; Kurokawa, K; Maeda, K; Miyata, S; Miyata, T; Monnier, VM; Sakai, H; Sugiyama, S; van Ypersole de Strihou, C; Witztum, JL | 1 |
| Boos, N; Nerlich, AG; Schleicher, ED | 1 |
| Horiuchi, S; Nishizawa, Y; Sugimoto, K; Yagihashi, S | 1 |
| Higami, Y; Horiuchi, S; Ikeda, T; Iwasaki, M; Shimokawa, I | 1 |
| Beisswenger, P; Brownlee, M; Giardino, I; Onorato, J; Shinohara, M; Thornalley, PJ; Thorpe, SR | 1 |
| Buijs, MJ; Damen, JJ; Kleter, GA; Ten Cate, JM | 1 |
| Asano, T; Futata, T; Horiuchi, S; Ikeda, K; Meng, J; Myint, T; Nagai, R; Sakata, N; Takebayashi, S; Taniguchi, N | 1 |
| Araki, T; Horiuchi, S; Ikeda, K; Kawasaki, Y; Nagai, R; Sano, H; Ueda, S; Yoshida, M | 1 |
| Doyu, M; Goto, Y; Horie, K; Inagaki, T; Maeda, K; Miyata, T; Sobue, G; Takeda, A; Wakai, M; Watanabe, M; Yasuda, T; Yasuda, Y | 1 |
| Kurokawa, K; Mitsuma, T; Miyata, T; Niwa, H; Sobue, G; Takeda, A; Wakai, M; Yasuda, Y | 1 |
| Horiuchi, S; Kimura, T; Miyakawa, T; Miyata, T; Takamatsu, J | 1 |
| Araki, T; Horiuchi, S; Ikeda, K; Nagai, R; Nakayama, H; Sakamoto, T; Sakata, N; Sano, H; Ueda, S; Yoshida, M | 1 |
| Baynes, JW; Fu, MX; Kurokawa, K; Miyata, T; Thorpe, SR; van Ypersele de Strihou, C | 1 |
| Iwamoto, H; Maruyama, I; Motomiya, Y; Oyama, N; Uchimura, T | 1 |
| Bangstad, HJ; Berg, TJ; Clausen, JT; Dahl-Jørgensen, K; Hanssen, KF; Torjesen, PA | 1 |
| Hermon, M; Hoeger, H; Lubec, B; Lubec, G | 1 |
| Cathcart, S; Clausen, J; Dominiczak, MH; Dorrian, CA; Shapiro, D | 1 |
| Aoyama, I; Hirasawa, Y; Miyazaki, S; Miyazaki, T; Morita, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S | 1 |
| LePage, K; Newkirk, MM; Niwa, T; Rubin, L | 1 |
| Horiuchi, S; Imanaga, Y; Itabe, H; Meng, J; Nagai, R; Sakata, N; Tachikawa, Y; Takano, T; Takebayashi, S | 1 |
| Hangai, M; Hinton, DR; Horiuchi, S; Ishibashi, T; Lopez, PF; Murata, T; Nagai, R; Ryan, SJ | 1 |
| Kurokawa, K; Miyata, T; van Ypersele de Strihou, C | 1 |
| Horiuchi, S; Imanaga, Y; Meng, J; Nagai, R; Sakata, N; Tachikawa, Y; Takebayashi, S | 1 |
| Gomi, K; Horiuchi, T | 1 |
| Aotaki-Keen, A; Handa, JT; Hjelmeland, LM; Lutty, GA; Matsunaga, H; Miyata, T; te Koppele, JM; Verzijl, N | 1 |
| Asayama, K; Hirano, A; Horiuchi, S; Kato, S; Kobayashi, M; Komori, T; Nagai, R; Shibata, N; Umahara, T | 1 |
| Asayama, K; Hirano, A; Horiuchi, S; Kato, M; Kato, S; Nakano, I; Nakashima, K; Ohama, E; Saito, M; Shibata, N | 1 |
| Horie, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Sakai, H; Saotome, N; Suzuki, D; Uchida, K; Yagame, M; Yasuda, Y | 1 |
| Aoyama, I; Katsuzaki, T; Miyazaki, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S | 1 |
| Daimon, M; Eguchi, H; Hirata, A; Igarashi, M; Kato, T; Manaka, H; Ohnuma, H; Ono, Y; Saito, T; Yamaguchi, H | 1 |
| Bretzel, RG; Brownlee, M; Hammes, HP; Lin, J; Schleicher, E | 1 |
| Nerlich, AG; Schleicher, ED | 1 |
| Alt, A; Bretzel, RG; Clausen, JT; Hammes, HP; Hoerauf, H; Laqua, H; Schleicher, E | 1 |
| Anderson, MM; Crowley, JR; Heinecke, JW; Requena, JR; Thorpe, SR | 1 |
| Monnier, VM; Obrenovich, M; Saxena, AK; Saxena, P; Weiss, MF; Wu, X | 1 |
| Fehrenbach, H; Funk, RH; Hofer, A; Kasper, M; Münch, G; Niwa, T; Pehlke, K; Schinzel, R; Wilsch-Bräuninger, M; Witt, M | 1 |
| Izuhara, Y; Kurokawa, K; Miyata, T; Sakai, H | 1 |
| Monnier, VM; Saxena, AK; Weiss, MF | 1 |
| Aotaki-Keen, A; Farboud, B; Handa, JT; Hjelmeland, LM; Miyata, T | 1 |
| Inagi, R; Kurokawa, K; Miyata, T; Sugiyama, S; Suzuki, D | 1 |
| Kameda, Y; Koike, T; Makita, Z; Takeuchi, M; Yanagisawa, K | 1 |
| Abraham, EC; Green, K; Shaw, SM; Swamy-Mruthinti, S; Zhao, HR | 1 |
| Ando, A; Fukunaga, M; Hori, M; Imai, E; Kawada, N; Kurokawa, K; Miyata, T; Moriyama, T | 1 |
| Berg, TJ; Birkeland, KI; Hanssen, KF; Kilhovd, BK; Thorsby, P | 1 |
| Araki, N; Horiuchi, S; Nagai, R; Shibayama, R | 1 |
| Barja, G; Baynes, JW; Bellmunt, MJ; López-Torres, M; Pamplona, R; Portero-Otín, M; Requena, JR; Romero, M; Ruiz, C; Thorpe, SR | 1 |
| Requena, JR; Stadtman, ER | 1 |
| Du Yan, S; Fu, C; Hofmann, M; Huber, B; Kislinger, T; Pischetsrieder, M; Qu, W; Schmidt, AM; Stern, D; Taguchi, A; Yan, SF | 1 |
| Baynes, JW; Litchfield, JE; Thorpe, SR | 1 |
| Hashimoto, A; Hyodo, T; Izumi, G; Kumano, K; Sakai, T; Shibata, K; Wang, H; Yokota, S | 1 |
| Amano, S; Araie, M; Horiuchi, S; Ishibashi, T; Kaji, Y; Matsubara, M; Murata, T; Nagai, R; Oshika, T; Usui, T; Yamashita, H | 1 |
| Horiuchi, S; Jono, T; Nagai, R; Sakata, N; Takebayashi, S; Uesugi, N | 1 |
| Danielsson, R; Fogarty, JF; Frank, A; Monnier, VM; Sell, DR | 1 |
| Araki, A; Deoreo, PB; Erhard, P; Glomb, MA; Kader-Attia, FA; Monnier, VM; Weiss, MF; Wu, YC | 1 |
| Arakawa, K; Horiuchi, S; Imanaga, Y; Itabe, H; Matsunaga, A; Nagai, R; Sakata, N; Sasaki, J; Takano, T; Takebayashi, S | 1 |
| Bucala, R; Kameda, Y; Koike, T; Makita, Z; Suzuki, T; Takeuchi, M | 1 |
| Karimian-Teherani, D; Melling, M; Menzel, EJ; Pfeiler, W; Schnallinger, M; Sobal, G; Zangerle, C | 1 |
| Fujita, Y; Hirano, H; Horie, K; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Uchida, K; Ueda, Y; van Ypersele de Strihou, C | 1 |
| Bank, RA; Bayliss, MT; Baynes, JW; Bijlsma, JW; DeGroot, J; Lafeber, FP; Oldehinkel, E; Tekoppele, JM; Thorpe, SR; Verzijl, N | 1 |
| Asayama, K; Hirano, A; Horiuchi, S; Jono, T; Kato, S; Kobayashi, M; Miyata, S; Nagai, R; Sasaki, S; Shibata, N | 1 |
| D'Agati, VD; Fu, C; Kislinger, T; Markowitz, GS; Pischetsrieder, M; Schmidt, AM; Stern, D; Taguchi, A; Tanji, N | 1 |
| Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C | 1 |
| Bank, RA; Baynes, JW; Bijlsma, JW; DeGroot, J; Lafeber, FP; Lyons, TJ; Shaw, JN; TeKoppele, JM; Thorpe, SR; Verzijl, N | 1 |
| Heidland, A; Schinzel, R; Sebeková, K; Waidheim, A | 1 |
| Chellan, P; Duve, Y; Glomb, MA; Jiang, CL; Madhun, Z; Nagaraj, RH; Sady, C | 1 |
| Hamada, Y; Horiuchi, S; Hotta, N; Kasuya, Y; Kato, K; Komori, T; Nagai, R; Nakamura, J; Naruse, K | 1 |
| Schmidt, AM; Stern, DM; Yan, SD; Yan, SF | 1 |
| Albano, E; Allochis, G; Bellomo, G; Cusaro, C; Mottaran, E; Rolla, R; Vay, D; Vidali, M | 1 |
| Fehrenbach, H; Funk, RH; Kasper, M; Kuhnt, AK; Roehlecke, C; Werner, C | 1 |
| Knerr, T; Lage, C; Niwa, T; Passlick-Deetjen, J; Pischetsrieder, M; Schaub, TP; Tauer, A | 1 |
| Horiuchi, S; Itabe, H; Jono, T; Myint, T; Nagai, R; Sakata, N; Takano, T; Takebayashi, S; Takeya, M; Taniguchi, N; Uesugi, N | 1 |
| Blazícek, P; Heidland, A; Krivosíková, Z; Schinzel, R; Sebeková, K; Spustová, V; Syrová, D | 1 |
| Dei, R; Goto, Y; Inagaki, T; Li, M; Miyata, T; Nakagomi, Y; Niwa, H; Sobue, G; Takeda, A; Wakai, M; Watanabe, M; Yamamoto, M; Yasuda, T; Yasuda, Y | 1 |
| Dimitrova, R; Hayashi, H; Ivanov, I; Mironova, R; Niwa, T | 1 |
| Ando, S; Horiuchi, S; Meng, J; Nagai, R; Sakata, N; Sasatomi, Y; Takebayashi, S; Uesugi, N | 1 |
| Anderson, JM; Scivittaro, V; Weiss, MF | 1 |
| Horiuchi, S; Imanaga, Y; Meng, J; Nagai, R; Sakata, N; Takebayashi, S | 1 |
| Berg, TJ; Borrebaek, J; Fjeldstad, K; Holkov, C; Kolset, SO; Prydz, K; Vuong, TT | 1 |
| Bjercke, RJ; Crow, MT; Denner, L; Haidacher, J; Juhasz, O; Sherwood, SJ; Sturgis, L; Tilton, RG; Yeh, CH; Zhang, XN | 1 |
| Iwamoto, H; Maruyama, I; Miura, K; Morisawa, M; Motomiya, Y; Yoshimura, Y | 1 |
| Endo, M; Higuchi, M; Koike, T; Makita, Z; Matsuda, A; Matsushita, T; Okamoto, T; Takeuchi, M; Tsuchida, K; Yanagisawa, K | 1 |
| Atwood, CS; Castellani, RJ; Founds, H; Fujii, J; Harris, PL; Perry, G; Sayre, LM; Smith, MA; Taniguchi, N; Vitek, MP | 1 |
| Blazícek, P; Boor, P; Bozek, P; Heidland, A; Pecovová, A; Schinzel, R; Sebeková, K; Syrová, D | 1 |
| Bitsch, I; Bretzel, RG; Federlin, KF; Geyer, J; Hammes, HP; Köpcke, W; Mavrakis, K; Netzel, M; Sauerland, C; Stracke, H; Werkmann, D | 1 |
| Heidland, A; Kientsch-Engel, R; Mazák, I; Nagy, J; Schinzel, R; Wagner, Z; Wittmann, I | 1 |
| Fujimori, K; Nakano, M; Sakurai, T; Shibusawa, Y; Shindo, H; Ueda, T | 1 |
| Higashi, T; Iwamoto, H; Maruyama, I; Motomiya, Y; Uchimura, T; Uji, Y | 1 |
| Baynes, JW; Jenkins, AJ; Lyons, TJ; Sochaski, MA; Thorpe, SR | 1 |
| Horiuchi, S; Meng, J; Nagai, R; Saito, T; Sakata, N; Takebayashi, S; Takeya, M; Uesugi, N | 1 |
| Erbersdobler, HF; Faist, V; Fölsch, UR; Günther, R; Zill, H | 1 |
| Goto, C; Kasahara, Y; Koizumi, S; Miyata, T; Morimoto, K; Ohta, K; Seki, H; Shimizu, M; Toma, T; Yachie, A; Yang, Y; Yokoyama, H | 1 |
| Blazícek, P; Heidland, A; Podracká, L; Schinzel, R; Sebeková, K; Syrová, D | 1 |
| Heidland, A; Kupcová, V; Schinzel, R; Sebeková, K | 1 |
| Faist, V; Heidland, A; Klvanová, J; Krajcoviová-Kudlácková, M; Schinzel, R; Sebeková, K | 1 |
| Lalla, E; Lamster, IB; Schmidt, AM; Stern, DM | 1 |
| Fu, L; Liang, JJ | 1 |
| Makita, Z; Takeuchi, M | 1 |
| Becker, CM; Humeny, A; Kislinger, T; Pischetsrieder, M | 1 |
| Erbersdobler, HF; Faist, V; Tasto, S; Wenzel, E | 1 |
| Hashiguchi, T; Iwamoto, H; Maruyama, I; Miura, M; Motomiya, Y; Okamura, H; Uchimura, T; Uji, Y | 1 |
| Blum, M; Dawczynski, J; Franke, S; Kasper, M; Stein, G; Strobel, J | 1 |
| Ahmed, N; Argirov, OK; Cordeiro, CA; Minhas, HS; Thornalley, PJ | 1 |
| Barja, G; Bellmun, MJ; Gredilla, R; Pamplona, R; Portero-Otín, M | 1 |
| Bräuer, R; Canet, CC; Drinda, S; Franke, S; Hein, G; Hüttich, C; Petrow, P; Stein, G | 1 |
| Baynes, JW; Shaw, JN; Thorpe, SR | 1 |
| Franke, S; John, U; Kauf, E; Misselwitz, J; Stein, G | 1 |
| Amano, S; Horiuchi, S; Kaji, Y; Nagai, R; Oshika, T; Suzuki, K; Tanaka, S; Usui, T | 1 |
| Araki, T; Hayase, F; Horiuchi, S; Miki Hayashi, C; Miyazaki, K; Nagai, R; Ono, T | 1 |
| Friess, U; Haslbeck, KM; Heuss, D; Kirchner, A; Neundörfer, B; Schleicher, ED | 1 |
| Metzger, T; Schinzel, R; Schwedler, SB; Wanner, C | 1 |
| Friess, U; Hempel, U; Kasper, M; Makita, Z; Schulze, E; Schwab, W; Simank, HG | 1 |
| Dei, R; Horie, K; Inagaki, T; Li, M; Miyata, T; Nakagomi, Y; Niwa, H; Sobue, G; Takeda, A; Washimi, Y; Watanabe, M; Yasuda, Y | 1 |
| Horiuchi, S; Ikeda, S; Kohno, S; Kondo, T; Miyahara, Y; Muroya, T; Urata, Y; Yasuoka, C | 1 |
| Brand, MD; Buckingham, JA; Cadenas, S; Clapham, JC; Pamplona, R; Portero-Otín, M; Requena, JR; Roebuck, SJ | 1 |
| Alderson, NL; Anderson, NL; Baynes, JW; Boyle, C; Canning, P; Chachich, M; Duffy, N; Frizzell, N; Gardiner, TA; Januszewski, AS; Stitt, A; Thorpe, SR | 1 |
| Hayase, F; Hayashi, MC; Horiuchi, S; Kinae, N; Masuda, S; Nagai, R; Unno, Y | 1 |
| Kikuchi, S; Makita, Z; Ogata, A; Shinpo, K; Takeuchi, M; Tashiro, K; Tsuji, S | 1 |
| Klvanová, J; Krajcovicová-Kudlácková, M; Schinzel, R; Sebeková, K | 1 |
| Horiuchi, S; Jono, T; Kimura, T; Kitamura, T; Miyazaki, K; Nagai, R; Takamatsu, J; Yuzuriha, T | 1 |
| Barja, G; Gredilla, R; Pamplona, R; Portero-Otín, M; Requena, J | 1 |
| Cai, W; Crandall, J; Dardaine, V; Goldberg, T; Oberstein, R; Peppa, M; Rayfield, EJ; Vlassara, H | 1 |
| Moh, A; Sakata, N; Takebayashi, S | 1 |
| Brammar, G; Burns, WC; Cao, Z; Cooper, ME; Forbes, JM; MCLennan, SV; Twigg, SM | 1 |
| Abd el Baki, RF; Andrassy, M; Bierhaus, A; Dugi, KA; Haering, HU; Hamann, A; Kasper, M; Kloeting, I; Mentz, S; Merz, W; Morcos, M; Nawroth, PP; Sayed, AA; Schleicher, E; Schmidt, AM; Schwenger, V; Stern, D; Tritschler, H; van der Woude, F; Waldherr, R; Yard, B; Ziegler, R | 1 |
| Koo, JR; Vaziri, ND | 1 |
| Bahner, U; Deppisch, R; Haug, U; Henle, T; Ritz, E; Schneider, H; Schwenger, V; Wanner, C; Weigel, K; Zeier, M | 1 |
| Becker, CM; Humeny, A; Kislinger, T; Niwa, T; Peich, CC; Pischetsrieder, M; Zhang, X | 1 |
| Adamczak, M; Chudek, J; Ficek, R; Heidland, A; Kokot, F; Schinzel, R; Wiecek, A | 1 |
| Berg, TJ; Birkeland, KI; Brownlee, M; Giardino, I; Hanssen, KF; Kilhovd, BK; Thornalley, PJ; Torjesen, PA | 1 |
| Andrassy, M; Bierhaus, A; Chen, J; Fritsche, A; Häring, HU; Humpert, P; Nawroth, PP; Rudofsky, G; Schiekofer, S; Schleicher, E; Schneider, J; Stefan, N; Stumvoll, M; Wendt, T | 1 |
| Biswas, J; Kumar, SK; Miriam, KC; Nagaraj, RH; Ramakrishnan, S; Sulochana, KN; Swamy-Mruthinti, S | 1 |
| Busch, M; Franke, C; Franke, S; Müller, A; Niwa, T; Stein, G; Wendt, T | 1 |
| Aoyama, I; Enomoto, A; Nakamura, S; Niwa, T; Tachikawa, T; Takayama, F; Tobita, K | 1 |
| Bakala, H; Borot-Laloi, C; Friguet, B; Hamelin, M | 1 |
| Boulanger, E; Guillausseau, PJ; Huijberts, M; Laloi-Michelin, M; Levy, B; Massin, P; Wautier, JL; Wautier, MP | 1 |
| Funk, RH; Geffarth, R; Kasper, M; Reber, F; Reichenbach, A; Schleicher, ED; Siegner, A | 1 |
| Blum, M; Dawczynski, J; Franke, S; Kubetschka, U; Stein, F; Stein, G; Strobel, J | 1 |
| Dworacka, M; Szczawińska, K; Szymańska, M; Wierusz-Wysocka, B; Winiarska, H | 1 |
| Blazícek, P; Dzúrik, R; Gazdíková, K; Heidland, A; Schinzel, R; Sebeková, K; Spustová, V; Syrová, D | 1 |
| Bach, LA; Cooper, ME; Gallicchio, M; Jerums, G; McRobert, EA | 1 |
| Chibber, R; Ferro, A; Kohner, E; Ritter, J; Ruggerio, D; Ruggiero, D; Xu, B | 1 |
| Bakala, H; Bismuth, J; Borot-Laloi, C; Corman, B; Delaval, E; Friguet, B; Hamelin, M | 1 |
| Hattori, M; He, C; McEvoy, R; Peppa, M; Vlassara, H; Zheng, F | 1 |
| Franke, S; Hein, G; Lehmann, G; Stein, G; Wiegand, R | 1 |
| Dawczynski, J; Franke, S; Niwa, T; Stahl, P; Stein, G; Strobel, J | 1 |
| Culbertson, SM; Ingold, KU; Morrison, LD; Vassilenko, EI | 1 |
| Anderson, MM; Heinecke, JW | 1 |
| Ferreira, AE; Ponces Freire, AM; Voit, EO | 1 |
| Braun, A; Busch, M; Fleck, C; Franke, S; Müller, A; Müller, UA; Schiel, R; Stein, G | 1 |
| Galler, A; Kiess, W; Kratzsch, J; Müller, G; Münch, G; Schinzel, R | 1 |
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| Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC | 1 |
| Hudson, BG; Jacob, J; Khalifah, RG; Serianni, AS; Thibaudeau, C; Voziyan, PA; Yildiz, A | 1 |
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| Barto, R; Schalkwijk, CG; Teerlink, T; Ten Brink, HJ | 1 |
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| Frischmann, M; Kientsch-Engel, R; Niwa, T; Pischetsrieder, M; Steinmann, K; Stopper, H; Zhang, X | 1 |
| Fragedaki, E; Frischmann, M; Heidland, A; Klassen, A; Nebel, M; Niwa, T; Pischetsrieder, M; Schupp, N; Sebekova, K; Stopper, H; Vienken, J; Völkel, W | 1 |
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| Bassal, S; Cooper, ME; Deemer, ER; El-Osta, A; Forbes, JM; Jerums, G; Long, DM; Osicka, TM; Panagiotopoulos, S; Pete, J; Thallas-Bonke, V; Thomas, MC; Thorpe, SR | 1 |
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| Amano, S; Horiuchi, S; Kaji, Y; Koito, W; Okamoto, F; Oshika, T | 1 |
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| Hoekman, K; Niessen, HW; Schalkwijk, CG; van Heijst, JW | 1 |
| Kalousová, M; Malbohan, IM; Soukupová, J; Stípek, S; Zák, A; Zima, T | 1 |
| Busch, AE; Huber, J; Linz, W; Rütten, H; Schäfer, S; Wihler, C | 1 |
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| Braun, M; Kalousová, M; Novotny, L; Vítek, L; Zima, T | 1 |
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| Franke, S; Hein, G; Lehmann, G; Niwa, T; Stein, G; Weiss, C | 1 |
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| Beckmann, MW; Dittrich, R; Hoffmann, I; Müller, A; Pischetsrieder, M; Stahl, P | 1 |
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| Brandstädt, A; Busch, M; Franke, S; Gerth, J; Hunsicker, LG; Ott, U; Stein, G; Wolf, G | 1 |
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| Arnstein, M; Cooper, ME; Coughlan, MT; Forbes, JM; Gasser, A; Long, DM; Pete, J; Thallas-Bonke, V; Thorpe, SR; Tong, DC | 1 |
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| Brodowsky, C; Kraus, T; Müller-Lux, A; Musiol, A; Schettgen, T; Tings, A | 1 |
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| Fujiwara, Y; Ikeda, T; Kiyota, N; Mera, K; Motomura, K; Nagai, R; Takeya, M | 1 |
| Fujiwara, Y; Ikeda, T; Iwao, Y; Mera, K; Motomura, K; Nagai, M; Nagai, R; Otagiri, M; Takeo, K; Tsurushima, K; Yoshitomi, M | 1 |
| Asai, K; Hirata, K; Ichimaru, Y; Kanazawa, H; Kyoh, S; Tochino, Y | 1 |
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| Fujiwara, Y; Mera, K; Nagai, R; Sakashita, N; Takeya, M; Yamagata, K | 1 |
| Cai, W; He, JC; Li, Z; Linden, E; Uribarri, J; Vlassara, H; Winston, J; Xue, C | 1 |
| Adolfsson, O; Baumeyer, A; Buetler, TM; Delatour, T; Foata, F; Heizmann, CW; Junod, S; Latado, H; Leclerc, E; Maurer, S; Newell, J; Parisod, V; Piguet, D; Richoz, J | 1 |
| Chang, T; Desai, K; Jia, X; Wang, X; Wu, L | 1 |
| Baynes, JW; Brock, JW; Fujiwara, Y; Maruyama, T; Mera, K; Murata, T; Nagai, M; Nagai, R; Otagiri, M | 1 |
| Diamanti-Kandarakis, E; Kandaraki, E; Katsikis, I; Panidis, D; Papavassiliou, AG; Piouka, A; Piperi, C | 1 |
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| Meyer, DM; Mills, LD; Mohammed, SF; Owan, TE; Redfield, MM; Schalkwijk, CG; Shapiro, BP | 1 |
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| Ferrucci, L; Lakatta, EG; Najjar, SS; Semba, RD; Sun, K | 1 |
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| Burner, T; Gohr, CM; Mitton, E; Monnier, V; Rosenthal, AK | 1 |
| Buetler, T; Delatour, T; Hegele, J; Maurer, S; Parisod, V; Richoz, J; Steven, M | 1 |
| Beck, J; Dalal, M; Ferrucci, L; Fried, LP; Semba, RD; Sun, K | 1 |
| Eriksson, UJ; Gittenberger-de Groot, AC; Molin, DG; Roest, PA; Schalkwijk, CG; van Iperen, L; Wentzel, P | 1 |
| Ferrucci, L; Fried, LP; Guralnik, JM; Patel, KV; Semba, RD; Sun, K | 1 |
| Borggrefe, M; Brueckmann, M; Hammes, HP; Kälsch, T; Kralev, S; Lang, S; Lin, J; Rippert, A; Süselbeck, T; Zimmerer, E | 1 |
| Berrou, J; Berthier, C; Boulanger, E; Hertig, A; Marti, HP; Mauviel, A; Rondeau, E; Tostivint, I; Verrecchia, F; Wautier, JL; Wautier, MP | 1 |
| Chang, CJ; Liou, SS; Liu, IM; Tzeng, TF | 1 |
| Crabb, JW; Gu, J; Gu, X; Nagaraj, RH; Ni, J; Yuan, X; Yue, X | 1 |
| Beck, J; Dalal, M; Ferrucci, L; Fried, LP; Guralnik, JM; Semba, RD; Sun, K; Varadhan, R; Walston, J | 1 |
| Fujimoto, S; Miyazaki, A; Yoshikawa, T | 1 |
| Dos Santos, CC; Gazendam, RP; Kneyber, MC; Kuiper, JW; Niessen, HW; Plötz, FB; Slutsky, AS | 1 |
| Huang, HW; Jao, YC; Wu, CF; Wu, CH; Yen, GC | 1 |
| Chung, BH; Kim, CS; Kim, J; Kim, JS; Kim, M; Kim, YS; Yi, SY | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Ozawa, Y | 1 |
| Coughlan, MT; Davis, TM; Davis, WA; Forbes, JM; Golledge, J; Norman, PE | 1 |
| Fujiwara, Y; Ikeda, T; Kiyota, N; Motomura, K; Nagai, R; Nohara, T; Takeya, M; Tsurushima, K | 1 |
| Bandinelli, S; Ferrucci, L; Guralnik, JM; Semba, RD; Sun, K | 2 |
| Davidge, ST; Jiang, Y; Sankaralingam, S; Sawamura, T; Xu, H | 1 |
| Bianchi, ME | 1 |
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| Ferrucci, L; Fink, JC; Semba, RD; Sun, K; Windham, BG | 1 |
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| Andrades, MÉ; Dal-Pizzol, F; Lorenzi, R; Moreira, JC; Nagai, R; Ritter, C | 1 |
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| Brimble, MA; Cooper, GJ; Woods, TM | 1 |
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| Colhoun, HM; Schalkwijk, CG; Scheijen, JL; Schram, MT; Stehouwer, CD; van Eupen, MG | 1 |
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| Cheng, L; Jin, C; Zhang, Y | 1 |
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| Delgado-Andrade, C; Navarro, MP; Peinado, MJ; Rubio, LA; Seiquer, I | 1 |
| Barzilay, JI; Bůžková, P; Cauley, JA; Djoussé, L; Ix, JH; Kizer, JR; Mukamal, KJ; Siscovick, DS; Tracy, RP; Zieman, SJ | 1 |
| Chen, WC; Lee, MR; Lee, WJ; Liang, KW; Lin, LY; Lin, SY; Liu, SH; Shen, CC; Sheu, ML; Sheu, WH; Tien, HR; Tsai, YC; Yang, TJ; Yeh, HY; Yi, YC | 1 |
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| Chen, L; Cross, AJ; Duan, Z; Hollenbeck, A; Jiao, L; Kahle, L; Risch, A; Sinha, R; Stolzenberg-Solomon, R; Striker, G; Subar, AF; Vlassara, H; Zimmerman, TP | 1 |
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| Cai, W; Díaz-Cisneros, FJ; Garay-Sevilla, ME; Macías-Cervantes, MH; Rodríguez-Soto, JM; Uribarri, J | 1 |
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| Choi, CW; Chung, YH; Ha, SK; Han, EH; Huh, YH; Hyon, JY; Jeong Ha, S; Jeong, HG; Jung, SK; Kim, HJ; Kim, Y; Lee, H; Lee, J; Min, JY; Park, J; Yun, SH | 1 |
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| Baldensperger, T; Dau, T; Di Sanzo, S; Glomb, MA; Heller, R; Henning, C; Kirkpatrick, JM; Leheis, A; Marx, C; Ori, A; Parca, L; Rändler, TL; Spengler, K; Wang, ZQ | 1 |
| Baylan, U; Korn, A; Krijnen, PAJ; Niessen, HWM; Schalkwijk, CG; Simsek, S | 1 |
| Abdulkadir, SA; Deaton, RJ; Helou, YB; Kajdacsy-Balla, A; Macias, V; Murphy, AB; Murray, M; Nonn, L; Sverdlov, M; Voisine, C; Wang, H; Zenner, ML | 1 |
| Blachut, D; Damasiewicz-Bodzek, A; Nowak, A; Nowalany-Kozielska, E; Przywara-Chowaniec, B; Tyrpień-Golder, K | 1 |
| Boulanger, E; Dubois, C; Fradin, C; Litke, R; Lo Guidice, JM; Paul-Constant, C; Rianha, S; Taront, S; Tessier, FJ | 1 |
| Jakhotia, S; Reddy Addi, U; Reddy, GB; Reddy, SS | 1 |
| Backofen, R; Batut, B; Blank, T; Buescher, JM; de Agüero, MG; Dokalis, N; Erny, D; Ganal-Vonarburg, SC; Lämmermann, T; Macpherson, AJ; Maron, FJM; Mayer, M; Mezö, C; Mossad, O; Nabavi, LS; Nent, E; Prinz, M; Szalay, A; Yilmaz, B | 1 |
| Bostick, JW; Mazmanian, SK | 1 |
| Chen, Q; Dong, L; Li, Y; Liu, L; Pan, D; Shi, R; Wu, Z; Zhang, J | 1 |
| Chen, J; Gao, C; Li, Y; Yang, Y; Yu, L; Zeng, M | 1 |
| Baskal, S; Tsikas, D | 1 |
| Anton, PM; Boulanger, E; Delayre-Orthez, C; Delguste, F; Genin, M; Guilbaud, A; Helou, C; Howsam, M; Jacolot, P; Niquet-Leridon, C; Nogueira Silva Lima, MT; Papazian, T; Tessier, FJ | 1 |
| Cai, Q; Fang, F; Ji, Y; Li, Y; Liu, W; Zhang, W | 1 |
| Chen, QJ; Chen, S; Dai, Y; Ding, FH; Li, FF; Li, LY; Lu, L; Shen, WF; Shen, Y; Wang, XQ; Wu, ZM | 1 |
| Balakrishna, S; Dias, CG; Venkataswamy, L | 1 |
| Bakker, W; Beekmann, K; Belzer, C; Rietjens, IMCM; van Dongen, KCW | 1 |
| Cho, KH; Kang, DJ; Kim, JE; Na, HJ; Nam, HS | 1 |
| Bai, Y; Chen, Z; Li, J; Li, S; Nie, C; Tu, A; Yuan, X; Zhai, R; Zhang, J; Zhang, M | 1 |
| Ha, SK; Jeong, YJ; Kang, J; Lee, HH; Lee, KW | 1 |
| Ferracane, R; Tagliamonte, S; Troise, AD; Vitaglione, P | 1 |
| Bai, Y; Chen, T; Chen, Z; Huang, T; Li, J; Xie, X; Yuan, X; Zhai, R; Zheng, M | 1 |
| He, J; Liu, H; Su, H; Sun, B; Yuan, XY | 1 |
| Friedrich, S; Grune, T; Hellwig, A; Henle, T; Müller, SK; Raupbach, J; Schnell, V | 1 |
| Ediga, HH; Hester, P; Madala, SK; Reddy, GB; Yepuri, A | 1 |
| Chen, J; Hao, S; Li, M; Li, N; Liu, H; Lu, Z; Quan, W; Wu, X; Xie, D; Xu, H | 1 |
23 review(s) available for lysine and n(6)-carboxymethyllysine
| Article | Year |
|---|---|
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles | 1996 |
New biomarkers of Maillard reaction damage to proteins.
Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles | 1996 |
Lipoxidation products as biomarkers of oxidative damage to proteins during lipid peroxidation reactions.
Topics: Aldehydes; Arteriosclerosis; Biomarkers; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Maillard Reaction; Malondialdehyde; Oxidative Stress; Proteins | 1996 |
Carbonyl stress and long-term uremic complications.
Topics: Arginine; Glycation End Products, Advanced; Humans; Lysine; Oxidative Stress; Uremia | 1998 |
The biology of the receptor for advanced glycation end products and its ligands.
Topics: Amyloidosis; Animals; Capillary Permeability; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Endothelium, Vascular; Erythrocytes; Glycation End Products, Advanced; Humans; Ligands; Lung; Lysine; Membrane Proteins; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Amyloid A Protein; Tumor Cells, Cultured | 2000 |
Receptor for advanced glycation end products, inflammation, and accelerated periodontal disease in diabetes: mechanisms and insights into therapeutic modalities.
Topics: Alveolar Bone Loss; Animals; Diabetes Mellitus; Disease Models, Animal; Endothelium, Vascular; Glycation End Products, Advanced; Hyperglycemia; Immunoglobulins; Ligands; Lysine; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Periodontal Diseases; Periodontitis; Phagocytes; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2001 |
Alternative routes for the formation of immunochemically distinct advanced glycation end-products in vivo.
Topics: Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Immunochemistry; Lysine; Models, Biological; Oxidation-Reduction | 2001 |
[Carbonyl stress significance in the pathogenesis of dialysis-related amyloidosis].
Topics: Amyloidosis; Diabetes Complications; Humans; Kidney Diseases; Lysine; Oxidative Stress; Renal Dialysis | 2003 |
Apoptotic killing of fibroblasts by matrix-bound advanced glycation endproducts.
Topics: Aging; Animals; Apoptosis; Cell Cycle; Extracellular Matrix; Fibroblasts; Glycation End Products, Advanced; Lysine; Maillard Reaction; Models, Biological; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction | 2005 |
Oxidative stress and neurodegeneration.
Topics: Aging; Alzheimer Disease; Glycation End Products, Advanced; Humans; Lysine; Nerve Degeneration; Oxidative Stress | 2005 |
Arguing for the motion: yes, RAGE is a receptor for advanced glycation endproducts.
Topics: Animals; Cattle; Glycation End Products, Advanced; Humans; Lung; Lysine; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction | 2007 |
Characteristics of neurons and glia in the brain of Fukuyama type congenital muscular dystrophy.
Topics: Astrocytes; Basement Membrane; Blotting, Western; Central Nervous System; Cerebral Cortex; Glycosylation; Humans; Immunohistochemistry; Lysine; Membrane Proteins; Muscle, Skeletal; Muscular Dystrophies; Neuroglia; Neurons | 2008 |
Dietary advanced glycation end-product restriction for the attenuation of insulin resistance, oxidative stress and endothelial dysfunction: a systematic review.
Topics: Diabetes Mellitus; Diet; Endothelium; Glycation End Products, Advanced; Humans; Insulin Resistance; Lysine; Oxidative Stress; Randomized Controlled Trials as Topic; Renal Insufficiency | 2013 |
The Maillard reaction and food allergies: is there a link?
Topics: Arginine; Dendritic Cells; Food Hypersensitivity; Glycation End Products, Advanced; Humans; Immunoglobulin E; Lysine; Maillard Reaction; Norleucine; Pyrroles; Receptors, Scavenger; T-Lymphocytes | 2014 |
Inhibition of AGEs formation by natural products.
Topics: Animals; Biological Products; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lipid Metabolism; Lysine | 2014 |
Maillard reaction products: some considerations on their health effects.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Diet; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Polymers | 2014 |
Review of the characteristics of food-derived and endogenous ne-carboxymethyllysine.
Topics: Consumer Product Safety; Diabetes Mellitus; Food Contamination; Food Handling; Glycation End Products, Advanced; Humans; Lysine | 2013 |
Role of receptor for advanced glycation end products (RAGE) and its ligands in cancer risk.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diabetes Mellitus; Disease Progression; Humans; Inflammation; Ligands; Lysine; Melanoma; Mice; Neoplasm Metastasis; Neoplasms; Oxidative Stress; Receptor for Advanced Glycation End Products; Risk Factors; Treatment Outcome | 2015 |
Dietary advanced glycation end products and their role in health and disease.
Topics: Agriculture; Chronic Disease; Cooking; Diet; Exercise; Food; Food Handling; Glycation End Products, Advanced; Health Status; Hot Temperature; Humans; Inflammation; Lysine; Mexico; Neurodegenerative Diseases; Oxidative Stress; Receptor for Advanced Glycation End Products; Solubility | 2015 |
Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation.
Topics: Biological Availability; Bone Diseases; Diet; Food; Food Contamination; Food Handling; Glycation End Products, Advanced; Hot Temperature; Humans; Lysine; Maillard Reaction; Neoplasms; Neurodegenerative Diseases; Oxidative Stress | 2016 |
Curcumin against advanced glycation end products (AGEs) and AGEs-induced detrimental agents.
Topics: Animals; Antioxidants; Apoptosis; Arginine; Cell Death; Cell Proliferation; Curcumin; Databases, Factual; DNA Damage; Glycation End Products, Advanced; Humans; Lysine; NF-kappa B; Oxidative Stress; Pyruvaldehyde; Receptor for Advanced Glycation End Products | 2019 |
Metabolic transit of dietary advanced glycation end-products - the case of N
Topics: Amino Acids; Diet; Digestion; Glycation End Products, Advanced; Humans; Lysine | 2021 |
Dietary N-epsilon-carboxymethyllysine as for a major glycotoxin in foods: A review.
Topics: Diet; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction | 2021 |
38 trial(s) available for lysine and n(6)-carboxymethyllysine
| Article | Year |
|---|---|
Immunohistochemical evidence for an increased oxidative stress and carbonyl modification of proteins in diabetic glomerular lesions.
Topics: Adult; Biomarkers; Biopsy, Needle; Culture Techniques; Diabetic Nephropathies; Female; Glomerular Mesangium; Glomerulonephritis, IGA; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Function Tests; Lysine; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Protein Denaturation; Reference Values; Sensitivity and Specificity | 1999 |
Serum levels of advanced glycation end products are increased in patients with type 2 diabetes and coronary heart disease.
Topics: Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Epitopes; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Multivariate Analysis; Risk Factors | 1999 |
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy.
Topics: Biomarkers; C-Reactive Protein; Cross-Over Studies; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Female; Food Analysis; Food, Formulated; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Inflammation Mediators; Lipid Peroxidation; Lysine; Male; Middle Aged; Pyruvaldehyde; Risk Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Norleucine; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Pyrroles; Pyruvaldehyde | 2003 |
Serum N-epsilon-(carboxymethyl)lysine is elevated in nondiabetic coronary heart disease patients.
Topics: Arteriosclerosis; C-Peptide; Carbohydrate Metabolism; Cholesterol, HDL; Coronary Disease; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Humans; Islets of Langerhans; Lipid Metabolism; Lipoproteins, HDL; Lysine; Male; Middle Aged; Oxidation-Reduction | 2002 |
The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membrane.
Topics: Aged; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Dialysis Solutions; Female; Humans; Hyaluronic Acid; Hydrogen-Ion Concentration; Imidazoles; Lysine; Male; Membranes, Artificial; Middle Aged; Peptide Fragments; Peritoneal Dialysis; Procollagen; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2004 |
Improvement of the quality of diabetes control and decrease in the concentrations of AGE-products in patients with type 1 and insulin-treated type 2 diabetes mellitus: results from a 10 year-prospective, population-based survey on the quality of diabetes
Topics: Adolescent; Adult; Arginine; Creatinine; Diabetes Complications; Diabetes Mellitus; Female; Germany; Glycation End Products, Advanced; Health Surveys; Humans; Insulin; Longitudinal Studies; Lysine; Male; Middle Aged; Prospective Studies; Time Factors | 2004 |
Genomic damage and circulating AGE levels in patients undergoing daily versus standard haemodialysis.
Topics: Adult; Aged; Arginine; C-Reactive Protein; Cross-Sectional Studies; DNA Damage; Female; Glycation End Products, Advanced; Humans; Imidazoles; Interleukin-6; Kidney Failure, Chronic; Lysine; Male; Micronucleus Tests; Middle Aged; Reference Values; Renal Dialysis | 2005 |
Reduced systemic advanced glycation end products in children receiving peritoneal dialysis with low glucose degradation product content.
Topics: Adolescent; Child; Child, Preschool; Cross-Over Studies; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Humans; Infant; Lysine; Molecular Weight; Osmolar Concentration; Peritoneal Cavity; Peritoneal Dialysis; Time Factors | 2007 |
Serum levels of the advanced glycation end products Nepsilon-carboxymethyllysine and pentosidine are not influenced by treatment with the angiotensin receptor II type 1 blocker irbesartan in patients with type 2 diabetic nephropathy and hypertension.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Biphenyl Compounds; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Linear Models; Lysine; Male; Middle Aged; Statistics, Nonparametric; Tetrazoles | 2008 |
Comparison of N-epsilon-(Carboxymethyl)Lysine levels and percentage of eosinophils in induced sputum for assessment of small airway involvements in asthma.
Topics: Adult; Aged; Asthma; Case-Control Studies; Eosinophils; Female; Forced Expiratory Volume; Humans; Lysine; Male; Methacholine Chloride; Middle Aged; Respiratory System; Sputum | 2008 |
Decrease in serum levels of advanced glycation end-products by short-term lifestyle modification in non-diabetic middle-aged females.
Topics: Adiposity; Adult; Aged; Arginine; Body Weight; Case-Control Studies; Diabetes Mellitus; Exercise; Female; Glycation End Products, Advanced; Humans; Life Style; Lysine; Middle Aged; Regression Analysis; Time Factors; Walking | 2009 |
Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction.
Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diastole; Female; Glycation End Products, Advanced; Humans; Hypertension; Imidazoles; Linear Models; Lysine; Male; Middle Aged; Multivariate Analysis; Netherlands; Skin; Statistics as Topic; Statistics, Nonparametric; Stroke Volume; Thiophenes; Ventricular Function, Left | 2010 |
Validity of measurement of two specific biomarkers for the assessment of small airways inflammation in asthma.
Topics: Adult; Androstadienes; Anti-Inflammatory Agents; Asthma; Beclomethasone; Biomarkers; Bronchi; Female; Fluticasone; Humans; Inflammation; Lysine; Male; Middle Aged; Nitric Oxide; Pulmonary Alveoli; Reproducibility of Results; Sputum | 2010 |
Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial.
Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Biomarkers; Biphenyl Compounds; Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Lysine; Male; Middle Aged; Prognosis; Tetrazoles | 2011 |
Olmesartan medoxomil is associated with decreased plasma AGEs, pentosidine, and N-(epsilon)-carboxymethyl-lysine levels in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Arginine; Benzimidazoles; Benzoates; Blood Pressure; Female; Glycation End Products, Advanced; Humans; Hypertension, Renal; Imidazoles; Inflammation; Kidney Failure, Chronic; Lysine; Male; Olmesartan Medoxomil; Oxidative Stress; Pilot Projects; Prospective Studies; Renal Dialysis; Telmisartan; Tetrazoles; Treatment Outcome | 2012 |
Suppression of native defense mechanisms, SIRT1 and PPARγ, by dietary glycoxidants precedes disease in adult humans; relevance to lifestyle-engendered chronic diseases.
Topics: Aged; Biomarkers; Cell Line; Chronic Disease; Cooking; Feeding Behavior; Female; Gene Expression; Gene Silencing; Glycation End Products, Advanced; Humans; Life Style; Lysine; Male; Middle Aged; Oxidative Stress; PPAR gamma; Sirtuin 1 | 2014 |
Effect of dietary advanced glycation end products on postprandial appetite, inflammation, and endothelial activation in healthy overweight individuals.
Topics: Adult; Appetite; Blood Glucose; Body Mass Index; Cross-Over Studies; Diet; Endothelium; Energy Intake; F2-Isoprostanes; Female; Ghrelin; Glucagon-Like Peptide 1; Glycation End Products, Advanced; Hot Temperature; Humans; Inflammation; Insulin; Lysine; Male; Middle Aged; Overweight; Oxidative Stress; Peptide YY; Postprandial Period; Steam; Triglycerides | 2014 |
The impact of salsalate treatment on serum levels of advanced glycation end products in type 2 diabetes.
Topics: Adiponectin; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pyruvaldehyde; Salicylates | 2014 |
Dietary intake of advanced glycation end products did not affect endothelial function and inflammation in healthy adults in a randomized controlled trial.
Topics: Aged; Biomarkers; Dietary Proteins; Endothelium, Vascular; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Hyperemia; Inflammation Mediators; Lysine; Maillard Reaction; Male; Maryland; Middle Aged; Peripheral Vascular Diseases; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk; Severity of Illness Index; Solubility; Vascular Resistance; Vasculitis | 2014 |
Maillard reaction products modulate gut microbiota composition in adolescents.
Topics: Adolescent; Animals; Bacteroides; Bifidobacterium; Cecum; Cross-Over Studies; Diet; Enterobacteriaceae; Escherichia coli; Feces; Furaldehyde; Humans; Intestines; Lactobacillus; Lysine; Maillard Reaction; Male; Microbiota; Rats; Rats, Wistar; Shigella | 2014 |
Dietary consumption of advanced glycation end products and pancreatic cancer in the prospective NIH-AARP Diet and Health Study.
Topics: Aged; Cohort Studies; Databases, Factual; Diet; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Male; Meat; Middle Aged; Normal Distribution; Pancreatic Neoplasms; Proportional Hazards Models; Prospective Studies; Risk; Sex Factors; Surveys and Questionnaires; United States | 2015 |
Effect of an advanced glycation end product-restricted diet and exercise on metabolic parameters in adult overweight men.
Topics: Adipose Tissue; Adult; Blood Glucose; Body Mass Index; Diet; Diet, Reducing; Energy Intake; Exercise; Feeding Behavior; Glycation End Products, Advanced; Humans; Lipids; Lipoproteins, HDL; Lysine; Male; Middle Aged; Obesity; Overweight; Oxygen Consumption; Pyruvaldehyde; Triglycerides; Waist Circumference; Weight Loss | 2015 |
Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease.
Topics: Adiponectin; Age Factors; Aged; Albuminuria; Chelating Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Estrogen Receptor alpha; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Intention to Treat Analysis; Lysine; Male; Metformin; Middle Aged; NF-E2-Related Factor 2; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Sevelamer; Sex Factors; Single-Blind Method; Sirtuin 1; White People | 2015 |
Effects of ginger on serum glucose, advanced glycation end products, and inflammation in peritoneal dialysis patients.
Topics: Adult; Aged; Arginine; Blood Glucose; C-Reactive Protein; Dietary Supplements; Double-Blind Method; E-Selectin; Female; Glycation End Products, Advanced; Humans; Inflammation; Intercellular Adhesion Molecule-1; Kidney Failure, Chronic; Lysine; Male; Malondialdehyde; Middle Aged; Peritoneal Dialysis; Treatment Outcome; Vascular Cell Adhesion Molecule-1; Zingiber officinale | 2015 |
Contribution of dietary advanced glycation end products (AGE) to circulating AGE: role of dietary fat.
Topics: Adult; Biomarkers; Body Mass Index; Breakfast; Cross-Over Studies; Diet, Western; Dietary Fats; Female; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Overweight; Pilot Projects; Postprandial Period; Receptor for Advanced Glycation End Products; Young Adult | 2015 |
Urinary excretion of dietary Maillard reaction products in healthy adult female cats.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cats; Dairy Products; Diet; Eating; Female; Kidney; Lysine; Lysinoalanine; Maillard Reaction; Pilot Projects | 2016 |
Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diet; Double-Blind Method; Female; Glucose Clamp Technique; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Imidazolidines; Insulin; Insulin Resistance; Lysine; Male; Middle Aged; Overweight; Pyruvaldehyde | 2016 |
Assessment of protein quality of soybean meal and 00-rapeseed meal toasted in the presence of lignosulfonate by amino acid digestibility in growing pigs and Maillard reaction products.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Brassica rapa; Diet; Dietary Proteins; Digestion; Glycine max; Ileum; Lignin; Lysine; Maillard Reaction; Swine | 2016 |
Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Imidazoles; Indians, North American; Kidney; Kidney Glomerulus; Losartan; Lysine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Pyruvaldehyde | 2016 |
Effects of Two Different Dietary Patterns on Inflammatory Markers, Advanced Glycation End Products and Lipids in Subjects without Type 2 Diabetes: A Randomised Crossover Study.
Topics: Adult; Biomarkers; Cholesterol; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet, Healthy; Diet, Western; Feeding Behavior; Female; Food Handling; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lipids; Lysine; Male; Middle Aged; Plasminogen Inactivators; Reference Values; Triglycerides; Young Adult | 2017 |
Effects of Cinnamon Consumption on Glycemic Indicators, Advanced Glycation End Products, and Antioxidant Status in Type 2 Diabetic Patients.
Topics: Aged; Antioxidants; Blood Glucose; Cinnamomum zeylanicum; Diabetes Mellitus, Type 2; Double-Blind Method; Glycated Hemoglobin; Glycation End Products, Advanced; Homeostasis; Humans; Insulin; Lysine; Malondialdehyde; Middle Aged | 2017 |
The improvement of oxidative stress by two proprietary herbal medicines in type 2 diabetes.
Topics: Aged; Biomarkers; Blood Pressure; Diabetes Mellitus, Type 2; Dinoprost; Drugs, Chinese Herbal; Female; Ginkgo biloba; Humans; Lysine; Male; Middle Aged; Oxidative Stress; Plant Extracts | 2018 |
Tocotrienol-Rich Vitamin E from Palm Oil (Tocovid) and Its Effects in Diabetes and Diabetic Nephropathy: A Pilot Phase II Clinical Trial.
Topics: Aged; Albuminuria; Biomarkers; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Kidney; Lysine; Malaysia; Male; Middle Aged; Pilot Projects; Prospective Studies; Time Factors; Tocotrienols; Treatment Outcome | 2018 |
Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study.
Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus; Endothelium, Vascular; Female; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Ornithine; Renal Dialysis | 2019 |
Soluble Receptor for Advanced Glycation End Products and Its Correlation with Vascular Damage in Adolescents with Obesity.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Humans; Lysine; Male; Pediatric Obesity; Receptor for Advanced Glycation End Products; Triglycerides; Vascular Diseases; Vascular Stiffness; Young Adult | 2019 |
Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study.
Topics: Biomarkers; Carotid Artery Diseases; Coronary Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet, Healthy; Endothelium, Vascular; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Olive Oil; Pyruvaldehyde; Single-Blind Method; Vasodilation | 2020 |
Urinary excretion of amino acids and their advanced glycation end-products (AGEs) in adult kidney transplant recipients with emphasis on lysine: furosine excretion is associated with cardiovascular and all-cause mortality.
Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Female; Glycation End Products, Advanced; Humans; Kidney Transplantation; Lysine; Male; Middle Aged; Prospective Studies; Tissue Donors; Transplant Recipients; Young Adult | 2021 |
710 other study(ies) available for lysine and n(6)-carboxymethyllysine
| Article | Year |
|---|---|
L-arginine reduces glomerular basement membrane collagen N epsilon-carboxymethyllysine in the diabetic db/db mouse.
Topics: Administration, Oral; Animals; Arginine; Basement Membrane; Collagen; Diabetes Mellitus, Experimental; Glycosylation; Kidney Glomerulus; Lysine; Mice; Mice, Mutant Strains | 1992 |
The extent of N epsilon-(carboxymethyl)lysine formation in lens proteins and polylysine by the autoxidation products of ascorbic acid.
Topics: 2,3-Diketogulonic Acid; Amino Acids; Animals; Ascorbic Acid; Borohydrides; Cattle; Crystallins; Kinetics; Lysine; Oxidation-Reduction; Polylysine | 1992 |
Identification of the carboxymethyllysine residue in the advanced stage of glycated human serum albumin.
Topics: Arginine; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Lysine; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Serum Albumin; Tyrosine | 1992 |
Age-dependent accumulation of N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)hydroxylysine in human skin collagen.
Topics: Aging; Collagen; Gas Chromatography-Mass Spectrometry; Glycosylation; Humans; Hydroxylysine; Lens, Crystalline; Lysine; Oxidation-Reduction; Skin | 1991 |
Effect of diabetes and aging on carboxymethyllysine levels in human urine.
Topics: Adolescent; Adult; Aged; Aging; Diabetes Mellitus, Type 1; Humans; Lysine; Middle Aged; Oxidation-Reduction | 1991 |
Decrease in skin collagen glycation with improved glycemic control in patients with insulin-dependent diabetes mellitus.
Topics: Arginine; Blood Glucose; Collagen; Diabetes Mellitus, Type 1; Humans; Hyperglycemia; Lysine; Maillard Reaction; Skin | 1991 |
Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataracts.
Topics: Aged; Arginine; Cataract; Cataract Extraction; Crystallins; Diabetic Retinopathy; Female; Glycosylation; Humans; Lysine; Male | 1991 |
Reaction of ascorbate with lysine and protein under autoxidizing conditions: formation of N epsilon-(carboxymethyl)lysine by reaction between lysine and products of autoxidation of ascorbate.
Topics: Ascorbic Acid; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Kinetics; Lysine; Oxidation-Reduction; Proteins | 1990 |
Oxidation of glycated proteins: age-dependent accumulation of N epsilon-(carboxymethyl)lysine in lens proteins.
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Chromatography, Ion Exchange; Crystallins; Humans; Infant; Lysine; Middle Aged; Oxidation-Reduction | 1989 |
Urinary carboxymethyl-lysine measurement as a potential indicator of diabetic complications.
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatinine; Diabetes Complications; Diabetes Mellitus; Humans; Lysine; Male | 1989 |
Identification of N epsilon-carboxymethyllysine as a degradation product of fructoselysine in glycated protein.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Crystallins; Free Radicals; Gas Chromatography-Mass Spectrometry; Glycoproteins; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Middle Aged; Mucoproteins; Oxidation-Reduction; Phosphates | 1986 |
Hyperoxic injury of immature guinea pig lung is mediated via hydroxyl radicals.
Topics: Animals; Animals, Newborn; Body Weight; Disease Models, Animal; Female; Guinea Pigs; Hydroxyl Radical; Hyperoxia; Lung; Lung Diseases; Lysine; Male; Oxidative Stress; Pregnancy; Survival Rate; Tyrosine | 1995 |
[Experiments with sausage meat on the formation of N epsilon-carboxymethyllysine].
Topics: Animals; Ascorbic Acid; Dairy Products; Food Handling; Glucose; Lysine; Meat Products; Nitrites; Phosphates | 1995 |
Pathways of formation of glycoxidation products during glycation of collagen.
Topics: Animals; Arginine; Carbon Isotopes; Collagen; Glucose; Glycosylation; Lysine; Oxidation-Reduction; Phosphates; Rats | 1995 |
Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen.
Topics: Aging; Animals; Arginine; Blood Proteins; Chromatography, High Pressure Liquid; Collagen; Energy Intake; Female; Food Deprivation; Glycation End Products, Advanced; Lysine; Oxidation-Reduction; Rats; Rats, Inbred BN; Skin | 1995 |
N epsilon-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins.
Topics: Aging; Antigens; Chromatography, Gel; Crystallins; Enzyme-Linked Immunosorbent Assay; Fructose; Glucose; Glycation End Products, Advanced; Glyoxal; Humans; Kinetics; Lysine; Maillard Reaction; Serum Albumin, Bovine | 1995 |
Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction.
Topics: Acetaldehyde; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Gas Chromatography-Mass Spectrometry; Glyoxal; Lysine; Maillard Reaction; Oxidation-Reduction; Proteins | 1995 |
Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose.
Topics: Arabinose; Glucose; Glycosylation; Glyoxal; Ketoses; Kinetics; Lysine; Oxidation-Reduction; Proteins | 1995 |
L-arginine reduces heart collagen accumulation in the diabetic db/db mouse.
Topics: Animals; Arginine; Collagen; Diabetes Mellitus; Hydroxyproline; Isomerism; Lysine; Mice; Mice, Mutant Strains; Myocardium; Tyrosine | 1994 |
L-arginine reduces kidney collagen accumulation and N-epsilon-(carboxymethyl)lysine in the aging NMRI-mouse.
Topics: Aging; Animals; Arginine; Basement Membrane; Collagen; Electrophoresis, Polyacrylamide Gel; Female; Glycosylation; Hydroxyproline; Kidney; Kidney Glomerulus; Lysine; Mice | 1994 |
Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction.
Topics: Animals; Antioxidants; Arginine; Chelating Agents; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Female; Glucose; Glycosylation; Kinetics; Lysine; Maillard Reaction; Oxidation-Reduction; Pentetic Acid; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Tendons | 1994 |
[Model experiments of the formation of N epsilon-carboxymethyllysine in food products].
Topics: Cooking; Food Analysis; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Models, Theoretical | 1994 |
Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Maillard Reaction; Male; Microcirculation; Middle Aged; Skin | 1993 |
The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions.
Topics: Arachidonic Acid; Copper; Glycation End Products, Advanced; Glyoxal; Humans; Lipid Peroxides; Lipoproteins, LDL; Lysine; Oxidation-Reduction | 1996 |
N (epsilon)-(carboxymethyl)lysine protein adduct is a major immunological epitope in proteins modified with advanced glycation end products of the Maillard reaction.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Antigen-Antibody Reactions; Cattle; Epitopes; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Kinetics; Lysine; Maillard Reaction; Mice; Mice, Inbred BALB C; Ribonuclease, Pancreatic; Serum Albumin; Serum Albumin, Bovine | 1996 |
Immunochemical detection of carboxymethylated Apo B-100 in copper-oxidized LDL.
Topics: Antibodies; Antibody Specificity; Apolipoprotein B-100; Apolipoproteins B; Copper; Cross Reactions; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Immunoblotting; Lipoproteins, LDL; Lysine; Serum Albumin, Bovine; Thiobarbituric Acid Reactive Substances | 1996 |
Amyloid beta 2-microglobulin is modified with N epsilon-(carboxymethyl)lysine in dialysis-related amyloidosis.
Topics: Amyloid; Amyloidosis; beta 2-Microglobulin; Blotting, Western; Chromatography, High Pressure Liquid; Dialysis; Enzyme-Linked Immunosorbent Assay; Epitopes; Glycation End Products, Advanced; Humans; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry | 1996 |
N epsilon-carboxymethyllysine and neurofibrillary tangles.
Topics: Animals; Brain Chemistry; Lysine; Mice; Neurofibrillary Tangles | 1996 |
Identification of advanced glycation end products of the Maillard reaction in Pick's disease.
Topics: Aged; Arginine; Brain; Dementia; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Maillard Reaction | 1996 |
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Child; Deferoxamine; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Fetus; Foam Cells; Guanidines; Humans; Immunohistochemistry; Intervertebral Disc; Intestinal Mucosa; Kidney; Lung; Lysine; Middle Aged; Molecular Structure; Myocardium; Oxidation-Reduction; Oxidative Stress; Pregnancy; Skin; Superoxide Dismutase; Thioctic Acid; Time Factors; Vitamin E | 1997 |
Implication of an increased oxidative stress in the formation of advanced glycation end products in patients with end-stage renal failure.
Topics: Amino Acid Sequence; Amyloid; Arginine; Ascorbic Acid; beta 2-Microglobulin; Glycation End Products, Advanced; Humans; Immunohistochemistry; In Vitro Techniques; Kidney Failure, Chronic; Lysine; Molecular Structure; Oxidative Stress; Renal Dialysis; Spectrometry, Fluorescence; Spectrometry, Mass, Fast Atom Bombardment; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Uremia | 1997 |
Photo-enhanced modification of human skin elastin in actinic elastosis by N(epsilon)-(carboxymethyl)lysine, one of the glycoxidation products of the Maillard reaction.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Elastin; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Photosensitivity Disorders; Skin; Skin Aging; Ultraviolet Rays | 1997 |
Hydroxyl radical mediates N epsilon-(carboxymethyl)lysine formation from Amadori product.
Topics: Catalase; Enzyme-Linked Immunosorbent Assay; Ferrous Compounds; Glucose; Glycated Serum Albumin; Glycation End Products, Advanced; Hydrogen Peroxide; Hydroxyl Radical; Lysine; Mannitol; Reactive Oxygen Species; Schiff Bases; Serum Albumin; Superoxide Dismutase | 1997 |
Protein oxidation of a hair sample kept in Alaskan ice for 800-1000 years.
Topics: Alaska; Child; Child, Preschool; Cysteic Acid; Female; Glycation End Products, Advanced; Hair; Humans; Ice; Isomerism; Lysine; Oxidation-Reduction; Proteins; Tissue Preservation; Tyrosine | 1997 |
N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Carbohydrate Metabolism; Child; Collagen; Crystallins; Humans; Lens, Crystalline; Lysine; Middle Aged; Oxidative Stress; Pyruvaldehyde; Ribonucleases; Skin | 1997 |
Carboxymethylethanolamine, a biomarker of phospholipid modification during the maillard reaction in vivo.
Topics: Adult; Diabetes Mellitus, Type 1; Erythrocyte Membrane; Ethanolamines; Female; Gas Chromatography-Mass Spectrometry; Glycation End Products, Advanced; Humans; Hydrolysis; Immune Sera; Lysine; Maillard Reaction; Male; Membrane Lipids; Models, Chemical; Oxidation-Reduction; Phosphatidylethanolamines; Phospholipids | 1997 |
Immunohistochemical localization of advanced glycation end products, pentosidine, and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons.
Topics: Adolescent; Aged; Aging; Alzheimer Disease; Arginine; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipofuscin; Lysine; Nerve Degeneration; Nerve Tissue Proteins; Neurons | 1997 |
The relationship between accumulation of advanced glycation end products and expression of vascular endothelial growth factor in human diabetic retinas.
Topics: Aged; Aged, 80 and over; Antibodies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelial Growth Factors; Epitopes; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lymphokines; Lysine; Male; Middle Aged; Retina; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
Hyperlipidemia and tissue contents of N epsilon-(carboxymethyl)lysine in streptozotocin diabetes.
Topics: Animals; Antibodies, Monoclonal; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Hyperlipidemias; Lipids; Lipoproteins; Lysine; Male; Rats; Rats, Wistar; Triglycerides | 1997 |
Age-dependent increase in ortho-tyrosine and methionine sulfoxide in human skin collagen is not accelerated in diabetes. Evidence against a generalized increase in oxidative stress in diabetes.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arginine; Child; Child, Preschool; Collagen; Diabetes Mellitus; Glucose; Humans; Infant; Infant, Newborn; Lysine; Methionine; Middle Aged; Oxidative Stress; Skin; Time Factors; Tyrosine | 1997 |
Technical note. The serum concentration of the advanced glycation end-product N epsilon-(carboxymethyl)lysine is increased in uremia.
Topics: Antibodies; Blood Proteins; Enzyme-Linked Immunosorbent Assay; Epitopes; Gas Chromatography-Mass Spectrometry; Glycation End Products, Advanced; Humans; Lysine; Osmolar Concentration; Peritoneal Dialysis, Continuous Ambulatory; Reference Values; Renal Dialysis; Uremia | 1997 |
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Animals; Antibodies; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Mice; Middle Aged; Nephrotic Syndrome; Norleucine; Pyrroles; Rabbits | 1997 |
1997 Volvo Award winner in basic science studies. Immunohistologic markers for age-related changes of human lumbar intervertebral discs.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Child; Child, Preschool; Fetus; Humans; Immunohistochemistry; Infant; Infant, Newborn; Intervertebral Disc; Lumbar Vertebrae; Lysine; Middle Aged | 1997 |
Localization in human diabetic peripheral nerve of N(epsilon)-carboxymethyllysine-protein adducts, an advanced glycation endproduct.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Fluorescent Antibody Technique; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Nerve Fibers, Myelinated; Peripheral Nerves; Proteins | 1997 |
Advanced glycosylation end products in adrenal lipofuscin.
Topics: Adrenal Cortex; Adrenal Glands; Aging; Animals; Antibodies; Brain; Cerebellum; Cerebral Cortex; Cytoplasmic Granules; Fluorescent Antibody Technique, Direct; Glycation End Products, Advanced; Immunoenzyme Techniques; Immunohistochemistry; Lipofuscin; Lysine; Male; Neurons; Purkinje Cells; Rats; Rats, Inbred F344; Zona Reticularis | 1998 |
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.
Topics: Acetone; Aldehydes; Animals; Cattle; Endocytosis; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glucose; Glutathione; Glycation End Products, Advanced; Glyoxal; Hyperglycemia; Ketones; Lactic Acid; Lactoylglutathione Lyase; Lysine; Pyruvaldehyde; Transfection; Tumor Cells, Cultured | 1998 |
Modification of amino acid residues in carious dentin matrix.
Topics: Amino Acids; Arginine; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Dental Caries; Dentin; Extracellular Matrix Proteins; Glycation End Products, Advanced; Glycosylation; Humans; Hydrolysis; Hydroxyproline; Lysine; Maillard Reaction; Ninhydrin; Protein Processing, Post-Translational; Spectrometry, Fluorescence | 1998 |
Glycoxidation in aortic collagen from STZ-induced diabetic rats and its relevance to vascular damage.
Topics: Aldehydes; Animals; Aorta; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Streptozocin | 1998 |
Conversion of Amadori product of Maillard reaction to Nepsilon-(carboxymethyl)lysine in alkaline condition.
Topics: Amino Acids; Antibodies, Monoclonal; Fructosamine; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Serum Albumin; Serum Albumin, Bovine; Sodium Hydroxide | 1998 |
Advanced glycation end products co-localized with astrocytes and microglial cells in Alzheimer's disease brain.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Astrocytes; Cytoplasmic Granules; Extracellular Space; Glycoconjugates; Hippocampus; Humans; Lysine; Microglia; Staining and Labeling | 1998 |
Accelerated formation of N epsilon-(carboxymethyl) lysine, an advanced glycation end product, by glyoxal and 3-deoxyglucosone in cultured rat sensory neurons.
Topics: Animals; Apoptosis; Culture Techniques; Deoxyglucose; Dose-Response Relationship, Drug; Ganglia, Spinal; Glycation End Products, Advanced; Glyoxal; Guanidines; Lysine; Neurons, Afferent; Rats; Rats, Sprague-Dawley | 1998 |
Localization of identified advanced glycation end-product structures, N epsilon(carboxymethyl)lysine and pentosidine, in age-related inclusions in human brains.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Brain; Entorhinal Cortex; Glycation End Products, Advanced; Hippocampus; Humans; Immunoenzyme Techniques; Inclusion Bodies; Lipofuscin; Lysine; Maillard Reaction; Middle Aged; Ubiquitins | 1998 |
Immunochemical approaches to AGE-structures: characterization of anti-AGE antibodies.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Antibody Specificity; Cloning, Molecular; Enzyme-Linked Immunosorbent Assay; Epitopes; Glycation End Products, Advanced; Immunohistochemistry; Lysine; Mice; Mice, Inbred BALB C | 1998 |
Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: is there oxidative stress in uremia?
Topics: Adult; Aged; Arginine; Carbohydrates; Case-Control Studies; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Lipids; Lysine; Malondialdehyde; Middle Aged; Oxidation-Reduction; Oxidative Stress; Uremia | 1998 |
N epsilon-(carboxymethyl)lysine in blood from maintenance hemodialysis patients may contribute to dialysis-related amyloidosis.
Topics: Adult; Aged; Aged, 80 and over; Amyloidosis; Animals; beta 2-Microglobulin; Biomarkers; Carpal Tunnel Syndrome; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Hemoglobins; Humans; Lysine; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Methylguanidine; Middle Aged; Rabbits; Renal Dialysis; Spinal Diseases | 1998 |
The advanced glycation end product Nepsilon-(carboxymethyl)lysine is increased in serum from children and adolescents with type 1 diabetes.
Topics: Adolescent; Animals; Antibodies, Monoclonal; Child; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Rabbits; Sensitivity and Specificity | 1998 |
Aromatic hydroxylation in animal models of diabetes mellitus.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Fructosamine; Hydroxylation; Kidney; Lysine; Malondialdehyde; Mice; Rats; Rats, Inbred BB; Rats, Sprague-Dawley; Streptozocin; Tyrosine | 1998 |
Factors in human serum interfere with the measurement of advanced glycation endproducts.
Topics: Antibodies; Antibodies, Monoclonal; Blood Physiological Phenomena; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Hot Temperature; Humans; Lysine; Reference Standards | 1998 |
Immunohistochemical detection of imidazolone and N(epsilon)-(carboxymethyl)lysine in aortas of hemodialysis patients.
Topics: Aged; Aorta; Arginine; Arteriosclerosis; Deoxyglucose; Female; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Uremia | 1998 |
Advanced glycation endproducts (AGE) on IgG, a target for circulating antibodies in North American Indians with rheumatoid arthritis (RA).
Topics: Adult; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodies; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Immunoblotting; Immunoglobulin G; Immunoglobulin Heavy Chains; Immunoglobulin M; Indians, North American; Lysine; Male; Middle Aged; Nitroblue Tetrazolium; Ontario; Rheumatoid Factor | 1998 |
Immunohistochemical localization of different epitopes of advanced glycation end products in human atherosclerotic lesions.
Topics: Adult; Aged; Antibodies, Monoclonal; Aorta; Arteriosclerosis; Enzyme-Linked Immunosorbent Assay; Epitopes; Extracellular Matrix; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipoproteins, LDL; Lysine; Macrophages; Male; Middle Aged; Tunica Intima | 1998 |
Advanced glycation end products in age-related macular degeneration.
Topics: Adult; Aged; Aged, 80 and over; Choroidal Neovascularization; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Keratins; Lysine; Macular Degeneration; Pigment Epithelium of Eye | 1998 |
Increased advanced glycation end products in atherosclerotic lesions of patients with end-stage renal disease.
Topics: Aged; Aorta; Apolipoproteins B; Arteriosclerosis; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Failure, Chronic; Lysine; Male; Middle Aged | 1999 |
Purification and characterization of a new enzyme, N-alkylglycine oxidase from Cladosporium sp. G-10.
Topics: Amino Acid Oxidoreductases; Cladosporium; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Weight; Sarcosine; Temperature | 1999 |
Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Bruch Membrane; Choroid; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Infant; Lysine; Middle Aged; Pigment Epithelium of Eye; Retinal Drusen | 1999 |
Advanced glycation endproducts are deposited in neuronal hyaline inclusions: a study on familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation.
Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Antibodies; Female; Glycation End Products, Advanced; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Motor Neurons; Neurofilament Proteins; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitins | 1999 |
Astrocytic hyaline inclusions contain advanced glycation endproducts in familial amyotrophic lateral sclerosis with superoxide dismutase 1 gene mutation: immunohistochemical and immunoelectron microscopical analyses.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Astrocytes; Cytoplasmic Granules; Female; Glycation End Products, Advanced; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Lewy Bodies; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Mutation; Neurofibrils; Neurons; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitins | 1999 |
Increased erythrocyte 3-DG and AGEs in diabetic hemodialysis patients: role of the polyol pathway.
Topics: Adult; Aged; Aldehyde Reductase; Arginine; Creatinine; Deoxyglucose; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Female; Glycation End Products, Advanced; Hemoglobins; Humans; Imidazoles; In Vitro Techniques; Lysine; Male; Middle Aged; Polymers; Renal Dialysis; Sorbitol; Uremia | 1999 |
Increased serum levels of pentosidine, but not carboxymethyl lysine, in type 2 diabetes without obvious diabetic nephropathy.
Topics: Albuminuria; Arginine; Biomarkers; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Reference Values | 1999 |
Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations.
Topics: Adult; Deoxyglucose; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Leukocyte Common Antigens; Lysine; Male; Middle Aged; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Pyruvaldehyde; Risk Factors; T-Lymphocytes | 1999 |
N(epsilon)-(carboxymethyl)lysine in atherosclerotic vascular lesions as a marker for local oxidative stress.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aorta; Arteriosclerosis; Biomarkers; Child; Child, Preschool; Culture Techniques; Female; Fetus; Glycation End Products, Advanced; Humans; Immunohistochemistry; Infant; Infant, Newborn; Lipid Peroxidation; Lysine; Male; Middle Aged; Muscle, Smooth, Vascular; Oxidative Stress; Pregnancy; Reference Values; Sensitivity and Specificity | 1999 |
N(epsilon)(carboxymethyl)lysin and the AGE receptor RAGE colocalize in age-related macular degeneration.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Epiretinal Membrane; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Lysine; Macular Degeneration; Male; Membrane Proteins; NF-kappa B; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Retinal Neovascularization | 1999 |
The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation.
Topics: Aldehydes; Catalase; Cations; Cells, Cultured; Chelating Agents; Glycosylation; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Lysine; Maillard Reaction; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Processing, Post-Translational; Ribonuclease, Pancreatic; Serine; Sodium Azide | 1999 |
Protein aging by carboxymethylation of lysines generates sites for divalent metal and redox active copper binding: relevance to diseases of glycoxidative stress.
Topics: Animals; Ascorbic Acid; Binding Sites; Biopolymers; Catalysis; Cations, Divalent; Collagen; Copper; Diabetes Mellitus, Experimental; Free Radicals; Glycation End Products, Advanced; Humans; Hydrogen Peroxide; Kidney Failure, Chronic; Lysine; Methylation; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Serine | 1999 |
Experimental induction of AGEs in fetal L132 lung cells changes the level of intracellular cathepsin D.
Topics: Antibodies; Cathepsin D; Cell Line; Cell Membrane; Cell Nucleus; Cell Size; Cytosol; Epithelial Cells; Gene Expression Regulation, Enzymologic; Glycation End Products, Advanced; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lung; Lysine; Lysosomes; Microscopy, Electron; Pulmonary Fibrosis; RNA, Messenger | 1999 |
Carbonyl stress: increased carbonyl modification of tissue and cellular proteins in uremia.
Topics: Aldehydes; Carbohydrate Metabolism; Glycation End Products, Advanced; Humans; Lipid Metabolism; Lipid Peroxidation; Lysine; Oxidative Stress; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Proteins; Uremia | 1999 |
Pharmacological modulation of AGEs: a unique role for redox-active metal ions.
Topics: Animals; Antioxidants; Chelating Agents; Diabetes Mellitus; Glycation End Products, Advanced; Guanidines; Humans; Kidney Failure, Chronic; Lysine; Metals; Oxidation-Reduction; Oxidative Stress; Peritoneal Dialysis; Uremia | 1999 |
Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.
Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Aging; Animals; Antibodies; Antibody Specificity; Arginine; Bruch Membrane; Cattle; Choroid Plexus; Extracellular Matrix Proteins; Glycation End Products, Advanced; Humans; Immunohistochemistry; Infant; Lysine; Middle Aged | 1999 |
Increased carbonyl modification by lipids and carbohydrates in diabetic nephropathy.
Topics: Animals; Carbohydrate Metabolism; Cells, Cultured; Diabetic Nephropathies; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Glomerulus; Lipid Metabolism; Lipid Peroxidation; Lysine; Malondialdehyde; Oxidation-Reduction; Rats | 1999 |
Detection of noncarboxymethyllysine and carboxymethyllysine advanced glycation end products (AGE) in serum of diabetic patients.
Topics: Animals; Antibodies; Cattle; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Peptides; Rabbits; Renal Dialysis | 1999 |
Evidence of a glycemic threshold for the development of cataracts in diabetic rats.
Topics: Animals; Blood Glucose; Cataract; Densitometry; Diabetes Mellitus, Experimental; Differential Threshold; Dose-Response Relationship, Drug; Fundus Oculi; Glycated Hemoglobin; Glycation End Products, Advanced; Lens, Crystalline; Lysine; Male; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors | 1999 |
Increased oxidative stress in mouse kidneys with unilateral ureteral obstruction.
Topics: Animals; Disease Models, Animal; Fibrosis; Glycation End Products, Advanced; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Kidney; Lysine; Male; Membrane Proteins; Mice; Oxidative Stress; RNA, Messenger; Ureteral Obstruction | 1999 |
Autoantibody against N(epsilon)-(carboxymethyl)lysine: an advanced glycation end product of the Maillard reaction.
Topics: Animals; Autoantibodies; Crystallins; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Epitopes; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Male; Rats; Rats, Wistar | 1999 |
Thyroid status modulates glycoxidative and lipoxidative modification of tissue proteins.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Deoxyguanosine; DNA Damage; Endopeptidases; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glycation End Products, Advanced; Glycosylation; Hyperthyroidism; Hypothyroidism; Lipid Peroxidation; Liver; Lysine; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Thyroid Hormones | 1999 |
Conversion of lysine to N(epsilon)-(carboxymethyl)lysine increases susceptibility of proteins to metal-catalyzed oxidation.
Topics: Aging; Animals; Catalysis; Cattle; Lysine; Metals; Oxidation-Reduction; Serum Albumin, Bovine | 1999 |
N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression.
Topics: Animals; Diabetes Mellitus; Endothelium, Vascular; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Lung; Lysine; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; NF-kappa B; Phagocytes; Protein Binding; Protein Processing, Post-Translational; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renal Insufficiency; Serum Albumin; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 1999 |
Oxygen is not required for the browning and crosslinking of protein by pentoses: relevance to Maillard reactions in vivo.
Topics: Aging; Animals; Antioxidants; Arabinose; Arginine; Cattle; Cross-Linking Reagents; Diabetes Mellitus; Fluorescence; Glucose; In Vitro Techniques; Lysine; Maillard Reaction; Oxidation-Reduction; Oxygen; Pentoses; Proteins; Ribonucleases | 1999 |
In vitro and in vivo generation and kinetics of glycosylation products in peritoneal dialysis effluents.
Topics: Adult; Arginine; Dialysis Solutions; Glycation End Products, Advanced; Humans; In Vitro Techniques; Lysine; Male; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum | 1998 |
Advanced glycation end products in diabetic corneas.
Topics: Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal; Basement Membrane; Cell Adhesion; Collagen; Corneal Diseases; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Female; Glucose-6-Phosphate; Glycation End Products, Advanced; Glycosylation; Humans; Immunoenzyme Techniques; Laminin; Lysine; Male; Mice; Middle Aged | 2000 |
Glycoxidative modification of AA amyloid deposits in renal tissue.
Topics: Adult; Aged; Amyloid; Collagen; Extracellular Matrix; Female; Glycation End Products, Advanced; Glycosylation; Humans; Kidney; Laminin; Lysine; Male; Middle Aged; Oxidation-Reduction; Serum Amyloid A Protein | 2000 |
A syndrome of molybdenosis, copper deficiency, and type 2 diabetes in the moose population of south-west Sweden.
Topics: Animals; Arginine; Case-Control Studies; Copper; Deer; Deficiency Diseases; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Kidney; Liver; Lysine; Molybdenum; Sweden | 2000 |
Mechanisms for the formation of glycoxidation products in end-stage renal disease.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Enzyme Inhibitors; Female; Glucose; Glycation End Products, Advanced; Guanidines; Humans; Kidney Failure, Chronic; Lysine; Maillard Reaction; Male; Middle Aged; Oxidation-Reduction; Peritoneal Dialysis; Renal Dialysis | 2000 |
In vivo and in vitro evidence for the glycoxidation of low density lipoprotein in human atherosclerotic plaques.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Aortic Diseases; Arteriosclerosis; Chelating Agents; Child; Child, Preschool; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Infant; Lipoproteins, LDL; Lysine; Male; Middle Aged; Nitric Oxide Synthase; Phosphatidylcholines; Thiobarbituric Acid Reactive Substances | 2000 |
Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo.
Topics: Animals; Antibodies; Cattle; Chromatography, Affinity; Cross Reactions; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glyceraldehyde; Glyoxal; Humans; Immunoblotting; Kidney Failure, Chronic; Lysine; Maillard Reaction; Oxidation-Reduction; Pyruvaldehyde; Rabbits; Renal Dialysis | 2000 |
Differential scanning calorimetry, biochemical, and biomechanical analysis of human skin from individuals with diabetes mellitus.
Topics: Aged; Aged, 80 and over; Anisotropy; Biomechanical Phenomena; Calorimetry, Differential Scanning; Collagen; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Lysine; Protein Denaturation; Skin | 2000 |
Advanced glycation and lipidoxidation of the peritoneal membrane: respective roles of serum and peritoneal fluid reactive carbonyl compounds.
Topics: Adult; Aged; Aldehydes; Arginine; Ascitic Fluid; Dialysis Solutions; Filtration; Glucose; Glycation End Products, Advanced; Hot Temperature; Humans; Kidney Failure, Chronic; Lipid Peroxidation; Lysine; Middle Aged; Peritoneal Dialysis; Peritoneum; Sterilization; Uremia | 2000 |
Age-related accumulation of Maillard reaction products in human articular cartilage collagen.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Cartilage, Articular; Child; Child, Preschool; Collagen; Collagenases; Cross-Linking Reagents; Female; Femur; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Skin; Spectrometry, Fluorescence | 2000 |
Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adult; Aged; Aldehydes; Amyotrophic Lateral Sclerosis; Arginine; Deoxyguanosine; Glycosylation; Humans; Imidazoles; Lipid Peroxidation; Lysine; Male; Middle Aged; Motor Neurons; Oxidative Stress; Spinal Cord; Superoxide Dismutase | 2000 |
Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease.
Topics: Adult; Antibodies; Arginine; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Diseases; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reference Values; RNA, Messenger | 2000 |
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines | 2000 |
Effect of collagen turnover on the accumulation of advanced glycation end products.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arginine; Aspartic Acid; Cartilage, Articular; Child; Child, Preschool; Chondrocytes; Collagen; Glycation End Products, Advanced; Humans; Kinetics; Lysine; Middle Aged; Skin | 2000 |
Evidence for accumulation of advanced glycation end products in acute renal failure.
Topics: Acute Kidney Injury; Animals; Bicarbonates; Creatinine; Glycation End Products, Advanced; Lysine; Male; Nephrectomy; Rats; Rats, Wistar; Reference Values; Urea; Ureter | 2000 |
Maillard reactions by alpha-oxoaldehydes: detection of glyoxal-modified proteins.
Topics: Aged; Aging; Antibodies; Cataract; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Proteins; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human | 2000 |
Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients.
Topics: Aldehyde Reductase; Blood Glucose; Blood Proteins; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Erythrocytes; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Reference Values; Rhodanine; Thiazolidines | 2000 |
Antibodies against advanced glycation end product Nepsilon-(carboxymethyl)lysine in healthy controls and diabetic patients.
Topics: Adult; Aged; Autoantibodies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Immunoglobulin G; Lysine; Male; Middle Aged; Serum Albumin | 2000 |
Resistance of L132 lung cell clusters to glyoxal-induced apoptosis.
Topics: Anoikis; Apoptosis; Caspase 3; Caspases; Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Epithelial Cells; Glycation End Products, Advanced; Glyoxal; Humans; Hyaluronan Receptors; Integrin beta1; Lung; Lysine; Spheroids, Cellular | 2000 |
In vitro formation of N(epsilon)-(carboxymethyl)lysine and imidazolones under conditions similar to continuous ambulatory peritoneal dialysis.
Topics: Dialysis Solutions; Fluorescence; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Peritoneal Dialysis, Continuous Ambulatory; Serum Albumin; Time Factors | 2001 |
Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Chelating Agents; Copper; Edetic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Guanidines; Humans; Immunohistochemistry; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Male; Malondialdehyde; Middle Aged; Pentetic Acid; Receptors, Immunologic; Receptors, Scavenger | 2001 |
Circulating advanced glycation end product levels in rats rapidly increase with acute renal failure.
Topics: Acute Kidney Injury; Animals; Antioxidants; Glutathione Peroxidase; Glycation End Products, Advanced; Lipid Peroxidation; Lipofuscin; Lysine; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors | 2001 |
Neuronal and glial advanced glycation end product [Nepsilon-(carboxymethyl)lysine]] in Alzheimer's disease brains.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Neuroglia; Neurons | 2001 |
Evidence for non-enzymatic glycosylation in Escherichia coli.
Topics: Bacterial Proteins; Deoxyglucose; Dimerization; Escherichia coli; Fluorescence; Glycosylation; Humans; Imidazoles; Interferon-gamma; Lysine; Protein Processing, Post-Translational; Recombinant Proteins; Spectrometry, Fluorescence | 2001 |
Possible involvement of altered RGD sequence in reduced adhesive and spreading activities of advanced glycation end product-modified fibronectin to vascular smooth muscle cells.
Topics: Amino Acids; Animals; Arginine; Cell Adhesion; Cells, Cultured; Collagen; Electrophoresis, Polyacrylamide Gel; Fibronectins; Glycation End Products, Advanced; Glycosylation; Humans; Immunochemistry; Lysine; Muscle, Smooth, Vascular; Oligopeptides; Sodium Dodecyl Sulfate; Swine | 2000 |
Oxidative stress and increased expression of growth factors in lesions of failed hemodialysis access.
Topics: Adult; Aged; Arteriovenous Anastomosis; Arteriovenous Fistula; Arteriovenous Shunt, Surgical; Biomarkers; Constriction, Pathologic; Endothelin-1; Female; Growth Substances; Humans; Hyperplasia; Iron; Kidney Failure, Chronic; Lipid Peroxidation; Lysine; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Platelet-Derived Growth Factor; Polytetrafluoroethylene; Renal Dialysis; Transforming Growth Factor beta; Tunica Intima; Vascular Patency | 2001 |
Carboxymethyllysine in dermal tissues of diabetic and nondiabetic patients with chronic renal failure: relevance to glycoxidation damage.
Topics: Aged; Animals; Antibodies, Monoclonal; Collagen; Dermis; Diabetic Nephropathies; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Mice; Mice, Inbred BALB C; Middle Aged | 2001 |
The AGE product N epsilon-(carboxymethyl)lysine serum albumin is a modulator of proteoglycan expression in polarized cultured kidney epithelial cells.
Topics: Animals; Cell Line; Chromatography, Gel; Chromatography, Ion Exchange; Dogs; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Glucosamine; Glucose; Glycation End Products, Advanced; Kidney; Lysine; Proteoglycans; Serum Albumin; Sulfates; Sulfur Radioisotopes; Tritium | 2001 |
Requirement for p38 and p44/p42 mitogen-activated protein kinases in RAGE-mediated nuclear factor-kappaB transcriptional activation and cytokine secretion.
Topics: Cell Line; Cytokines; Enzyme Activation; Humans; Lysine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; Multigene Family; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Tyrosine | 2001 |
Immunochemical assay of hemoglobin with N(epsilon)-(carboxymethyl)lysine at lysine 66 of the beta chain.
Topics: Acetaldehyde; Adult; Aged; Antibodies, Monoclonal; Hemoglobins; Humans; Immunoassay; Lysine; Middle Aged; Peptide Fragments; Renal Dialysis; Sensitivity and Specificity | 2001 |
Increased levels of vascular endothelial growth factor and advanced glycation end products in aqueous humor of patients with diabetic retinopathy.
Topics: Aged; Aqueous Humor; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelial Growth Factors; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lymphokines; Lysine; Male; Middle Aged; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Free Radicals; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Middle Aged; Neurofibrillary Tangles | 2001 |
[Increased levels of circulating advanced glycation end products in a model of acute renal insufficiency in rats].
Topics: Acute Kidney Injury; Animals; Antioxidants; Creatinine; Glycation End Products, Advanced; Lipofuscin; Lysine; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar | 2001 |
Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Glycosylation; Lysine; Male; Neural Conduction; Oxidation-Reduction; Peripheral Nerves; Rats; Rats, Wistar; Reference Values; Thiamine; Time Factors | 2001 |
N(epsilon)-(carboxymethyl)lysine levels in patients with type 2 diabetes: role of renal function.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Oxidative Stress | 2001 |
Sunlight induces N epsilon-(carboxymethyl)lysine formation from glycated polylysine-iron(III) complex.
Topics: Glycated Serum Albumin; Glycation End Products, Advanced; Glycosylation; Humans; In Vitro Techniques; Iron; Lysine; Magnetic Resonance Spectroscopy; Photochemistry; Polylysine; Serum Albumin; Sunlight | 2001 |
Potential value of CML-Hb in predicting the progression of bone cysts in dialysis-related amyloidosis.
Topics: Amyloidosis; Biomarkers; Bone Cysts; Female; Hemoglobins; Hip Joint; Humans; Lysine; Male; Middle Aged; Renal Dialysis | 2001 |
Isotope dilution gas chromatography/mass spectrometry method for the determination of methionine sulfoxide in protein.
Topics: Collagen; Crystallins; Cyanogen Bromide; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Lipoproteins, LDL; Lysine; Methionine; Oxidative Stress; Proteins; Skin | 2001 |
Glycoxidation-modified macrophages and lipid peroxidation products are associated with the progression of human diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Diabetic Nephropathies; Female; Glycosylation; Humans; Immunohistochemistry; Kidney Glomerulus; Leukocyte Common Antigens; Lipid Peroxidation; Lysine; Macrophages; Male; Middle Aged; Oxidation-Reduction; Phosphatidylcholines; Receptors, Immunologic; Receptors, Scavenger; Scavenger Receptors, Class A; Severity of Illness Index | 2001 |
RAGE expression and AGE-induced MAP kinase activation in Caco-2 cells.
Topics: Adenocarcinoma; Blotting, Western; Caco-2 Cells; Caseins; Colonic Neoplasms; Enzyme Activation; Glycation End Products, Advanced; Glycoside Hydrolases; Hot Temperature; Humans; Lysine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Denaturation; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transcription, Genetic | 2001 |
Cytoprotective role of heme oxygenase (HO)-1 in human kidney with various renal diseases.
Topics: Adolescent; Aged; Arginine; Child; Cytoprotection; Hematuria; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Immunohistochemistry; Kidney; Kidney Diseases; Lysine; Membrane Proteins; Proteinuria | 2001 |
Plasma levels of advanced glycation end products in children with renal disease.
Topics: Adolescent; Aged; Child; Female; Fluorescence; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lipofuscin; Lysine; Male; Middle Aged; Reference Values; Renal Dialysis | 2001 |
Markedly elevated levels of plasma advanced glycation end products in patients with liver cirrhosis - amelioration by liver transplantation.
Topics: Adolescent; Adult; Aged; Creatinine; Cystatin C; Cystatins; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Liver Cirrhosis; Liver Transplantation; Lysine; Male; Middle Aged; Renal Insufficiency | 2002 |
Plasma levels of advanced glycation end products in healthy, long-term vegetarians and subjects on a western mixed diet.
Topics: Adult; Aging; Diabetes Mellitus; Diet; Diet, Vegetarian; Edible Grain; Enzyme-Linked Immunosorbent Assay; Fabaceae; Fluorescence; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney; Lysine | 2001 |
Conformational study of N(epsilon)-(carboxymethyl)lysine adducts of recombinant gammaC-crystallin.
Topics: Circular Dichroism; Crystallins; Glycation End Products, Advanced; Humans; Lysine; Protein Denaturation; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Fluorescence; Temperature | 2001 |
Qualitative determination of specific protein glycation products by matrix-assisted laser desorption/ionization mass spectrometry Peptide mapping.
Topics: Deoxyglucose; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Glucose; Glycoproteins; Glycosylation; Lysine; Maillard Reaction; Muramidase; Peptide Mapping; Pyruvaldehyde; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship | 2002 |
Effect of heat-treated proteins on selected parameters of the biotransformation system in the rat.
Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Dietary Proteins; Enzyme Activation; Glutathione; Glutathione Transferase; Hot Temperature; Intestinal Mucosa; Kidney; Liver; Lysine; Lysinoalanine; Maillard Reaction; Male; Rats; Rats, Wistar | 2002 |
Marked increases in macrophage colony-stimulating factor and interleukin-18 in maintenance hemodialysis patients: comparative study of advanced glycation end products, carboxymethyllysine and pentosidine.
Topics: Adult; Aged; Arginine; Cytokines; Female; Glycation End Products, Advanced; Hemoglobins; Humans; Interleukin-18; Lysine; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Regression Analysis; Renal Dialysis | 2002 |
Advanced glycation end-products in corneas of patients with keratoconus.
Topics: Adult; Aged; Cornea; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Keratoconus; Lysine; Male; Middle Aged | 2002 |
Assay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to Nepsilon-carboxymethyl-lysine- and Nepsilon-(1-carboxyethyl)lysine-modified a
Topics: Aminoquinolines; Biochemistry; Carbamates; Chromatography; Chromatography, High Pressure Liquid; Glucose; Glycation End Products, Advanced; Indicators and Reagents; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Temperature; Time Factors | 2002 |
Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins.
Topics: Aging; Animals; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Food Deprivation; Gas Chromatography-Mass Spectrometry; Lysine; Male; Malondialdehyde; Mitochondria; Models, Statistical; Myocardium; Oxidative Stress; Phospholipids; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors | 2002 |
Identification of the advanced glycation end products N(epsilon)-carboxymethyllysine in the synovial tissue of patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; B-Lymphocytes; Cell Differentiation; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Macrophages; Male; Middle Aged; Oxidative Stress; Synovial Membrane; T-Lymphocytes | 2002 |
N epsilon-(carboxymethyl)lysine (CML) as a biomarker of oxidative stress in long-lived tissue proteins.
Topics: Biomarkers; Collagen; Gas Chromatography-Mass Spectrometry; Humans; Lysine; Oxidative Stress; Proteins; Skin | 2002 |
Advanced glycation end products in children with chronic renal failure and type 1 diabetes.
Topics: Adolescent; Arginine; Child; Child, Preschool; Creatinine; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lysine; Male; Reference Values | 2002 |
Advanced glycation end products in Descemet's membrane and their effect on corneal endothelial cell.
Topics: Animals; Antibodies, Monoclonal; Cattle; Cell Adhesion; Cell Division; Cells, Cultured; Collagen Type I; Collagen Type IV; Descemet Membrane; Endothelium, Corneal; Enzyme-Linked Immunosorbent Assay; Fibronectins; Glycation End Products, Advanced; Glycosylation; Guanidines; Immunoenzyme Techniques; Laminin; Lysine | 2001 |
Conversion of Amadori products of the Maillard reaction to N(epsilon)-(carboxymethyl)lysine by short-term heating: possible detection of artifacts by immunohistochemistry.
Topics: Animals; Antibodies, Monoclonal; Artifacts; Borohydrides; Glycation End Products, Advanced; Guanidines; Hot Temperature; Humans; Immunoenzyme Techniques; Liver; Lysine; Maillard Reaction; Male; Polyamines; Rats; Rats, Wistar; Serum Albumin; Skin | 2002 |
N(epsilon)-Carboxymethyllysine in diabetic and non-diabetic polyneuropathies.
Topics: Adult; Aged; Biopsy; Blotting, Western; Charcot-Marie-Tooth Disease; Diabetic Neuropathies; Female; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Oxidative Stress; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Sural Nerve | 2002 |
Advanced glycation end products and mortality in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; C-Reactive Protein; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Renal Dialysis; Serum Albumin; Survival Rate | 2002 |
Immunohistochemical demonstration of -(carboxymethyl)lysine protein adducts in normal and osteoarthritic cartilage.
Topics: Blotting, Western; Cartilage, Articular; Case-Control Studies; Chondrocytes; Cytoplasm; Extracellular Matrix; Glycation End Products, Advanced; Humans; Immunohistochemistry; Knee Joint; Lysine; Osteoarthritis; Proteins | 2002 |
Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease.
Topics: Adolescent; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Neuroglia; Neurons; Oxidative Stress | 2002 |
Nepsilon-(Carboxymethyl)lysine induces gamma-glutamylcysteine synthetase in RAW264.7 cells.
Topics: Animals; Base Sequence; Blotting, Western; Cell Line; DNA Primers; Electrophoretic Mobility Shift Assay; Glutamate-Cysteine Ligase; Glutathione; Lysine; MAP Kinase Signaling System; Mice; NF-kappa B; Protein Kinase C; Proto-Oncogene Proteins c-raf; RNA, Messenger; Transcription Factor AP-1 | 2002 |
Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.
Topics: Animals; Biomarkers; Carrier Proteins; Fatty Acids; Ion Channels; Lysine; Mice; Mice, Mutant Strains; Mitochondria, Muscle; Mitochondrial Proteins; Muscle, Skeletal; Oxidative Stress; Phospholipids; Proteins; Reactive Oxygen Species; Uncoupling Protein 3 | 2002 |
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.
Topics: Animals; Capillaries; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Extracellular Matrix; Female; Glycation End Products, Advanced; Laminin; Lysine; Pyridoxamine; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; RNA, Messenger | 2002 |
Peroxynitrite induces formation of N( epsilon )-(carboxymethyl) lysine by the cleavage of Amadori product and generation of glucosone and glyoxal from glucose: novel pathways for protein modification by peroxynitrite.
Topics: 2-Naphthylamine; Aldehydes; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glucose; Glyoxal; Guanidines; Ketoses; Lysine; Mice; Mice, Inbred BALB C; Peroxynitrous Acid; Serum Albumin; Tyrosine | 2002 |
Detection of N epsilon-(carboxymethyl)lysine (CML) and non-CML advanced glycation end-products in the anterior horn of amyotrophic lateral sclerosis spinal cord.
Topics: Aged; Amyotrophic Lateral Sclerosis; Autopsy; Axons; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Neurons; Spinal Cord | 2002 |
Advanced glycation end products and nutrition.
Topics: Diet; Diet, Vegetarian; Glycation End Products, Advanced; Humans; Lysine; Nutritional Physiological Phenomena | 2002 |
Accumulation of imidazolone, pentosidine and N(epsilon)-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyramidal Cells | 2002 |
Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls.
Topics: Aldehydes; Animals; Biomarkers; Energy Intake; Glutamates; Lysine; Male; Mitochondria, Heart; Mitochondrial Proteins; Oxidative Stress; Rats; Rats, Wistar; Reference Values; Time Factors | 2002 |
Contribution of superoxide to reduced antioxidant activity of glycoxidative serum albumin.
Topics: Antioxidants; Copper; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Glucose; Glycation End Products, Advanced; Glycosylation; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Malondialdehyde; Oxidants; Oxidation-Reduction; Oxidative Stress; Protein Binding; Serum Albumin; Serum Albumin, Human; Superoxides; Time Factors | 2002 |
Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine.
Topics: Animals; Cells, Cultured; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Gene Expression; Glomerular Mesangium; Glycation End Products, Advanced; Guanidines; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serum Albumin, Bovine | 2002 |
Activation of tubular epithelial cells in diabetic nephropathy.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Epithelium; Glycation End Products, Advanced; Humans; Kidney; Kidney Tubules; Lysine; NF-kappa B; Rats; Rats, Brattleboro; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reference Values; Serum Albumin; Transcription, Genetic; Urine | 2002 |
Effects of diabetes, insulin and antioxidants on NO synthase abundance and NO interaction with reactive oxygen species.
Topics: Animals; Antioxidants; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Insulin; Lysine; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine | 2003 |
Relative quantification of N(epsilon)-(Carboxymethyl)lysine, imidazolone A, and the Amadori product in glycated lysozyme by MALDI-TOF mass spectrometry.
Topics: Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Imidazoles; Lysine; Maillard Reaction; Muramidase; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2003 |
Relationship between plasma level of parathyroid hormone and carboxymethyllysine in hemodialyzed patients--does it exist?
Topics: Body Mass Index; Calcium; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Parathyroid Hormone; Phosphorus; Renal Dialysis; Uremia | 2003 |
Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Humans; Imidazoles; Immunoassay; Lysine; Pyruvaldehyde; Sensitivity and Specificity | 2003 |
Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor kappaB in PBMCs.
Topics: Animals; Blotting, Western; Cattle; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Glucose Clamp Technique; Humans; Hyperglycemia; Leukocytes, Mononuclear; Lysine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins p21(ras); Signal Transduction; Transfection | 2003 |
Immunolocalization and quantification of advanced glycation end products in retinal neovascular membranes and serum: a possible role in ocular neovascularization.
Topics: Adolescent; Adult; Blood Glucose; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Epiretinal Membrane; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Pyruvaldehyde; Retinal Neovascularization; Retinal Vasculitis | 2002 |
Are advanced glycation end products cardiovascular risk factors in patients with CRF?
Topics: Adult; Aged; Aged, 80 and over; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Hypertrophy, Left Ventricular; Imidazoles; Kidney Failure, Chronic; Kidney Transplantation; Lysine; Male; Middle Aged; Renal Dialysis; Retrospective Studies; Risk Factors | 2003 |
An inhibitor of advanced glycation end product formation reduces N epsilon-(carboxymethyl)lysine accumulation in glomeruli of diabetic rats.
Topics: Age Factors; Animals; Antibodies, Monoclonal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Glomerular Mesangium; Glycation End Products, Advanced; Kidney; Kidney Glomerulus; Lysine; Rats; Rats, Inbred OLETF; Rats, Inbred Strains; Thiadiazoles; Thiazolidines | 2003 |
Increased level of glycoxidation product N(epsilon)-(carboxymethyl)lysine in rat serum and urine proteins with aging: link with glycoxidative damage accumulation in kidney.
Topics: Aging; Animals; Antibodies; Antibody Specificity; Basement Membrane; Biomarkers; Collagen; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Immunohistochemistry; Kidney; Lysine; Male; Oxidative Stress; Proteins; Rats; Rats, Wistar | 2003 |
N(carboxymethyl)lysine as a biomarker for microvascular complications in type 2 diabetic patients.
Topics: Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Microcirculation; Middle Aged | 2003 |
Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Dose-Response Relationship, Drug; Female; Glycation End Products, Advanced; Glyoxal; Guanidines; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lysine; Male; Neurons; Niacinamide; Organ Culture Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retina; Thioctic Acid; Vanadates | 2003 |
Advanced glycation end-products in anterior chamber aqueous of cataractous patients.
Topics: Aged; Albumins; Aqueous Humor; Arginine; Blotting, Western; Cataract; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Female; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Protein Binding | 2003 |
Effects of ramipril in nondiabetic nephropathy: improved parameters of oxidatives stress and potential modulation of advanced glycation end products.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Blood Glucose; Blood Pressure; Creatinine; Cystatin C; Cystatins; Diabetic Nephropathies; Female; Glomerulonephritis; Glycation End Products, Advanced; Homocysteine; Humans; Lipofuscin; Lysine; Male; Malondialdehyde; Middle Aged; Nephritis, Interstitial; Oxidative Stress; Polycystic Kidney Diseases; Ramipril; Severity of Illness Index; Statistics as Topic; Treatment Outcome | 2003 |
The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.
Topics: Animals; Binding Sites; Biosensing Techniques; Blood Proteins; Blotting, Western; Cattle; Chromatography, Affinity; Cloning, Molecular; Cytoskeletal Proteins; Detergents; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Humans; Kidney; Ligands; Lysine; Membrane Proteins; Microfilament Proteins; Phosphoproteins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serum Albumin; Time Factors; Tumor Cells, Cultured; Tyrosine | 2003 |
Impairment of vascular endothelial nitric oxide synthase activity by advanced glycation end products.
Topics: Animals; Antibodies; Aorta; Arginine; Blood Pressure; Cells, Cultured; Citrulline; Diabetes Mellitus; Endothelium, Vascular; Enzyme Inhibitors; Female; Femoral Artery; Glycation End Products, Advanced; Humans; In Vitro Techniques; Lysine; Male; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rabbits; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Vasodilation | 2003 |
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix.
Topics: Adenosine Triphosphate; Aging; Animals; Blotting, Western; Cell Survival; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Immunochemistry; Lysine; Male; Methylation; Microscopy, Electron; Mitochondria; Mitochondria, Liver; Oxygen; Oxygen Consumption; Peptides; Rats; Rats, Wistar; Stress, Physiological; Time Factors | 2003 |
Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice.
Topics: Administration, Oral; Aging; Albuminuria; Animals; Animals, Newborn; Blood Glucose; Creatinine; Crosses, Genetic; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Islets of Langerhans; Lysine; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Pyruvaldehyde | 2003 |
Advanced glycation end-products pentosidine and N epsilon-carboxymethyllysine are elevated in serum of patients with osteoporosis.
Topics: Adult; Aged; Analysis of Variance; Arginine; Bone Resorption; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Osteoporosis | 2003 |
Increased levels of advanced glycation end products in human cataractous lenses.
Topics: Aged; Antibodies, Monoclonal; Arginine; Cataract; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lens, Crystalline; Lysine; Middle Aged; Oxidation-Reduction | 2003 |
Paradoxical impact of antioxidants on post-Amadori glycoxidation: Counterintuitive increase in the yields of pentosidine and Nepsilon-carboxymethyllysine using a novel multifunctional pyridoxamine derivative.
Topics: Antioxidants; Arginine; Biochemistry; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Glucose; Glycation End Products, Advanced; Ions; Lysine; Models, Chemical; Pyridoxamine; Ribose; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2003 |
Production of N(epsilon)-(carboxymethyl)lysine is impaired in mice deficient in NADPH oxidase: a role for phagocyte-derived oxidants in the formation of advanced glycation end products during inflammation.
Topics: Acetaldehyde; Animals; Glycation End Products, Advanced; Hydrogen Peroxide; Inflammation; Lysine; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Oxidants; Phagocytosis; Serine | 2003 |
A quantitative model of the generation of N(epsilon)-(carboxymethyl)lysine in the Maillard reaction between collagen and glucose.
Topics: Collagen; Glucose; Glycation End Products, Advanced; Guanidines; Kinetics; Lysine; Maillard Reaction; Models, Theoretical | 2003 |
Effect of smoking on risk factors for cardiovascular disease in patients with diabetes mellitus and renal insufficiency.
Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Homocysteine; Humans; Kidney Transplantation; Lysine; Middle Aged; Renal Dialysis; Renal Insufficiency; Risk Factors; Smoking | 2003 |
Impact of metabolic control and serum lipids on the concentration of advanced glycation end products in the serum of children and adolescents with type 1 diabetes, as determined by fluorescence spectroscopy and nepsilon-(carboxymethyl)lysine ELISA.
Topics: Adolescent; Adult; Age of Onset; Albuminuria; Blood Glucose; Child; Cholesterol; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Humans; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Lysine; Male; Reference Values; Regression Analysis; Spectrometry, Fluorescence; Triglycerides | 2003 |
Liquid chromatography-based determination of urinary free and total N(epsilon)-(carboxymethyl)lysine excretion in normal and diabetic subjects.
Topics: Adult; Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Glycated Hemoglobin; Humans; Lysine; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2003 |
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients.
Topics: Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus; Diet; Diet Records; Food Analysis; Food Handling; Glycation End Products, Advanced; Humans; Hypertension; Kidney Failure, Chronic; Lysine; Metabolic Clearance Rate; New York City; Peritoneal Dialysis; Pyruvaldehyde; Renal Dialysis; Smoking; Surveys and Questionnaires; Uremia | 2003 |
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.
Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine | 2003 |
Modification of proteins in vitro by physiological levels of glucose: pyridoxamine inhibits conversion of Amadori intermediate to advanced glycation end-products through binding of redox metal ions.
Topics: Animals; Carbon Isotopes; Diabetes Mellitus; Glucose; Glycation End Products, Advanced; Humans; Lysine; Metals; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Protein Processing, Post-Translational; Proteins; Pyridoxamine | 2003 |
Lack of recognition of Nepsilon-(carboxymethyl)lysine by the mouse liver reticulo-endothelial system: implications for pathophysiology.
Topics: Adult; Animals; Cells, Cultured; Chromatography, Gel; Female; Glycation End Products, Advanced; Humans; Liver; Lysine; Mice; Molecular Weight; Mononuclear Phagocyte System; Serum Albumin, Bovine | 2003 |
Identification of Nepsilon-(carboxymethyl)lysine-positive cells in astroglia-rich primary cultures.
Topics: Animals; Astrocytes; Blotting, Western; Brain Chemistry; Cell Culture Techniques; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Immunohistochemistry; Lysine; Rats; Rats, Wistar | 2003 |
Association between blood indoxyl sulfate and carbonyl stress marker in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Arginine; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Indican; Lysine; Male; Middle Aged; Regression Analysis; Renal Dialysis; Time Factors | 2003 |
Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics.
Topics: Acetaldehyde; Amines; Arginine; Diabetes Mellitus; Fructose; Glucose; Glycation End Products, Advanced; Glyoxylates; Humans; Ligands; Lysine; Membrane Proteins; Molecular Weight; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Recombinant Proteins; Regression Analysis; Ribose; Serum Albumin, Bovine; Spectrometry, Fluorescence | 2004 |
Changes in glycation of fibrous type I collagen during long-term in vitro incubation with glucose.
Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Collagen Type I; Fructosamine; Glucose; Glycosylation; Lysine; Solubility; Time Factors | 2003 |
In vitro glycoxidation of insoluble fibrous type I collagen: solubilization and advanced glycation end products.
Topics: Amidines; Animals; Arginine; Cattle; Collagen Type I; Glycation End Products, Advanced; Glycosylation; Lysine; Solubility | 2003 |
Tomato paste fraction inhibiting the formation of advanced glycation end-products.
Topics: Arginine; Blotting, Western; Chemical Fractionation; Enzyme-Linked Immunosorbent Assay; Food; Glucose; Glycation End Products, Advanced; Lysine; Molecular Weight; Nitroblue Tetrazolium; Norleucine; Oxidation-Reduction; Pyrroles; Rutin; Serum Albumin, Bovine; Solanum lycopersicum; Spectrometry, Fluorescence | 2004 |
Photoaging and oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Arginine; Cells, Cultured; Deoxyguanosine; Fibroblasts; Humans; Lysine; Mice; Mice, Hairless; Oxidative Stress; Skin; Skin Aging; Tyrosine; Ultraviolet Rays | 2003 |
Increased levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine in type 1 diabetic patients with impaired renal function: correlation with markers of endothelial dysfunction.
Topics: Adult; Aged; Blood Coagulation Factors; C-Reactive Protein; Case-Control Studies; Diabetes Mellitus, Type 1; E-Selectin; Endothelium, Vascular; Female; Glomerular Filtration Rate; Humans; Kidney; Lysine; Male; Middle Aged; Thrombomodulin; Vascular Cell Adhesion Molecule-1 | 2004 |
Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients.
Topics: Aldehydes; Alzheimer Disease; Cell Line; Cells, Cultured; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Immunohistochemistry; Lipid Peroxidation; Lysine; Membrane Proteins; Neurons; Olfactory Mucosa; Oxidative Stress | 2004 |
Nepsilon-(carboxymethyl)lysine, Nepsilon-(carboxyethyl)lysine and vascular cell adhesion molecule-1 (VCAM-1) in relation to peritoneal glucose prescription and residual renal function; a study in peritoneal dialysis patients.
Topics: Cross-Sectional Studies; Female; Glomerular Filtration Rate; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Peritoneal Dialysis; Vascular Cell Adhesion Molecule-1 | 2004 |
Increased production of urea hydrogen peroxide from Maillard reaction and a UHP-Fenton pathway related to glycoxidation damage in chronic renal failure.
Topics: Arginine; Female; Glycosides; Humans; Hydrogen Peroxide; Kidney; Kidney Failure, Chronic; Lysine; Maillard Reaction; Male; Middle Aged; Myocardium; Urea | 2004 |
Metal complexation by the peptide-bound maillard reaction products N(epsilon)-fructoselysine and N(epsilon)-carboxymethyllysine.
Topics: Copper; Lysine; Maillard Reaction; Metals; Peptides; Zinc | 2004 |
Nonenzymatic glycation at the N terminus of pathogenic prion protein in transmissible spongiform encephalopathies.
Topics: Animals; Arginine; Astrocytes; Binding, Competitive; Blotting, Western; Brain; Cricetinae; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glycosylation; Humans; Immunohistochemistry; Kinetics; Lysine; Mice; Mice, Inbred C57BL; Models, Biological; Oxygen; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Peptides; Precipitin Tests; Prion Diseases; Prions; Protein Isoforms; Protein Processing, Post-Translational; Protein Structure, Tertiary; PrPSc Proteins | 2004 |
N epsilon-carboxymethyllysine in brain aging, diabetes mellitus, and Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Cytoplasm; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Neurofibrillary Tangles; Neurons; Plaque, Amyloid; tau Proteins | 2004 |
AGEs, macrophage colony stimulating factor and vascular adhesion molecule blood levels are increased in patients with diabetic microangiopathy.
Topics: Aged; Biomarkers; Case-Control Studies; Coculture Techniques; Diabetic Angiopathies; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Female; Glycation End Products, Advanced; Humans; Lysine; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Umbilical Veins; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2004 |
Measurement of Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine in human plasma protein by stable-isotope-dilution tandem mass spectrometry.
Topics: Biomarkers; Blood Proteins; Chromatography, Liquid; Glycation End Products, Advanced; Humans; Hydrolysis; Indicator Dilution Techniques; Lipids; Lysine; Mass Spectrometry; Oxidation-Reduction; Renal Dialysis; Renal Insufficiency | 2004 |
N(omega)-(carboxymethyl)lysine depositions in human aortic heart valves: similarities with atherosclerotic blood vessels.
Topics: Adult; Aged; Aged, 80 and over; Aortic Valve; Arteriosclerosis; Biomarkers; Blood Vessels; Cadaver; Culture Techniques; Endothelium, Vascular; Female; Fibroblasts; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Mitral Valve; Probability; Reference Values | 2004 |
A possible involvement of the carboxymethylation process in carpal tunnel syndrome in hemodialysis patients.
Topics: Adult; Age of Onset; Aged; Carpal Tunnel Syndrome; Electrophysiology; Female; Hemoglobins; Humans; Lysine; Male; Methylation; Middle Aged; Multivariate Analysis; Neural Conduction; Regression Analysis; Renal Dialysis; Time Factors | 2004 |
Increased accumulation of the glycoxidation product Nepsilon-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Infant, Newborn; Lysine; Male; Myocardium; Oxidation-Reduction | 2004 |
Receptor for advanced glycation endproduct (RAGE)-mediated nuclear factor-kappaB activation in vasculitic neuropathy.
Topics: Adult; Aged; Charcot-Marie-Tooth Disease; Humans; Immunohistochemistry; Interleukin-6; Lysine; Middle Aged; NF-kappa B; Oxidative Stress; Peripheral Nervous System Diseases; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Sural Nerve; Vasculitis | 2004 |
The clinical chemome: a tool for the diagnosis and management of chronic disease.
Topics: Biomarkers; Chromatography, Liquid; Chronic Disease; Glycation End Products, Advanced; Humans; Lipid Metabolism; Lipids; Lysine; Mass Spectrometry; Oxidation-Reduction; Renal Dialysis; Renal Insufficiency | 2004 |
Liquid chromatographic method for the quantitative determination of Nepsilon-carboxymethyllysine in human plasma proteins.
Topics: Blood Proteins; Humans; Lysine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2004 |
Possible mechanism for medial smooth muscle cell injury in diabetic nephropathy: glycoxidation-mediated local complement activation.
Topics: Acrolein; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Complement Activation; Complement Membrane Attack Complex; Diabetic Nephropathies; Female; Glomerulosclerosis, Focal Segmental; Glycation End Products, Advanced; Humans; Hypertension; Kidney; Kidney Glomerulus; Lysine; Male; Middle Aged; Models, Biological; Nephrosclerosis; Oxidation-Reduction; Tunica Media | 2004 |
Advanced glycoxidation end products in commonly consumed foods.
Topics: Antibodies, Monoclonal; Cardiovascular Diseases; Cooking; Dietary Carbohydrates; Dietary Fats; Enzyme-Linked Immunosorbent Assay; Food Analysis; Food Handling; Glycation End Products, Advanced; Hot Temperature; Humans; Kidney Diseases; Lipid Peroxidation; Lysine; Maillard Reaction; Meat; Time Factors | 2004 |
Effect of advanced glycation end-products on gene expression and synthesis of TNF-alpha and endothelial nitric oxide synthase by endothelial cells.
Topics: Antibodies; Antineoplastic Agents; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glycation End Products, Advanced; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Lysine; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Serum Albumin; Serum Albumin, Human; Tumor Necrosis Factor-alpha; Umbilical Veins | 2004 |
N(epsilon)-(carboxymethyl)lysine proliferated CD34(+) cells from rat choroidal explant in culture.
Topics: Animals; Antigens, CD34; Cell Culture Techniques; Choroid; Choroidal Neovascularization; Glycation End Products, Advanced; Lysine; Male; Rats; Rats, Wistar; Time Factors | 2004 |
Galectin-3/AGE-receptor 3 knockout mice show accelerated AGE-induced glomerular injury: evidence for a protective role of galectin-3 as an AGE receptor.
Topics: Aldehydes; Animals; Cell Death; Cell Proliferation; Extracellular Matrix Proteins; Galectin 3; Glycation End Products, Advanced; Kidney; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Kinetics; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Proteinuria; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transforming Growth Factor beta | 2004 |
Overproduction of N(epsilon)-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of streptozotocin-diabetic rat.
Topics: Animals; Antibodies, Monoclonal; Choroid; Choroidal Neovascularization; Diabetes Mellitus, Experimental; Humans; Lysine; Male; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Serum Albumin; Streptozocin; Time Factors; Tissue Culture Techniques; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2004 |
Intact glycation end products containing carboxymethyl-lysine and glyoxal lysine dimer obtained from synthetic collagen model peptide.
Topics: Amino Acid Sequence; Collagen Type I; Dimerization; Glycation End Products, Advanced; Glyoxal; Humans; Lysine; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Protein Structure, Tertiary | 2004 |
Paradox of circulating advanced glycation end product concentrations in patients with congestive heart failure and after heart transplantation.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Heart Failure; Heart Transplantation; Humans; Kidney Failure, Chronic; Lipid Peroxidation; Lysine; Male; Middle Aged | 2004 |
Advanced glycation end products enhance expression of pro-apoptotic genes and stimulate fibroblast apoptosis through cytoplasmic and mitochondrial pathways.
Topics: Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cells, Cultured; Collagen; Cytoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Glycation End Products, Advanced; Humans; In Situ Nick-End Labeling; Lysine; Mice; Mitochondria; Oligonucleotide Array Sequence Analysis; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone.
Topics: Adult; Aged; Antibodies, Monoclonal; Aorta; Arginine; Arteriosclerosis; Binding, Competitive; Chromatography; Chromatography, High Pressure Liquid; Cytoplasm; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Foam Cells; Glycation End Products, Advanced; Humans; Imidazoles; Immunochemistry; Immunohistochemistry; Lysine; Male; Middle Aged; Models, Biological; Models, Chemical; Norleucine; Pyrroles; Temperature; Time Factors | 2004 |
Development of capture assays for different modifications of human low-density lipoprotein.
Topics: Animals; Antigen-Antibody Complex; Copper; Enzyme-Linked Immunosorbent Assay; Humans; Lipoproteins, LDL; Lysine; Malondialdehyde; Rabbits; Reproducibility of Results; Sensitivity and Specificity | 2005 |
Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes.
Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged | 2004 |
Conventional antibody against Nepsilon-(carboxymethyl)lysine (CML) shows cross-reaction to Nepsilon-(carboxyethyl)lysine (CEL): immunochemical quantification of CML with a specific antibody.
Topics: Animals; Antibodies, Monoclonal; Cattle; Cross Reactions; Eye Proteins; Glycation End Products, Advanced; Immunization; Immunoglobulin G; Lysine; Rabbits; Serum Albumin, Bovine | 2004 |
Proteins in human brain cortex are modified by oxidation, glycoxidation, and lipoxidation. Effects of Alzheimer disease and identification of lipoxidation targets.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blotting, Western; Brain; Carbon; Cerebral Cortex; Databases as Topic; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Fatty Acids, Unsaturated; Female; Glial Fibrillary Acidic Protein; Glycation End Products, Advanced; Glycolysis; Humans; Lipid Metabolism; Lipid Peroxidation; Lysine; Male; Malondialdehyde; NADH Dehydrogenase; Oxygen; Phenylhydrazines; Proteins; Silver Staining; Ubiquinone | 2005 |
Rapid and simple method for determination of Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine in urine using gas chromatography/mass spectrometry.
Topics: Child; Gas Chromatography-Mass Spectrometry; Glycation End Products, Advanced; Humans; Lysine; Reproducibility of Results; Time Factors | 2005 |
Clinical implications of N epsilon-(carboxymethyl)lysine, advanced glycation end product, in children and adolescents with type 1 diabetes.
Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Chronic Disease; Diabetes Complications; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Linear Models; Lysine; Male | 2005 |
Glyoxal inactivates glutamate transporter-1 in cultured rat astrocytes.
Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatography, High Pressure Liquid; Glutamic Acid; Glyoxal; Immunoblotting; Immunohistochemistry; Lysine; Rats | 2005 |
Advanced glycation end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study.
Topics: Adult; Blood Pressure; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Linear Models; Lysine; Male; Middle Aged; Multicenter Studies as Topic; Platelet Activating Factor; Prospective Studies | 2005 |
Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice.
Topics: Age Factors; Aging; Aldehydes; Animals; Body Weight; Dinoprost; Extracellular Matrix; Galectin 3; Glomerulonephritis; Glycation End Products, Advanced; Kidney Glomerulus; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Two immunochemical assays to measure advanced glycation end-products in serum from dialysis patients.
Topics: Adult; Aged; Antibodies, Monoclonal; Blood Chemical Analysis; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Middle Aged; Oxidative Stress; Renal Dialysis | 2005 |
The AGE/RAGE/NF-(kappa)B pathway may contribute to the pathogenesis of polyneuropathy in impaired glucose tolerance (IGT).
Topics: Aged; Biopsy; Charcot-Marie-Tooth Disease; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Glucose Intolerance; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; NF-kappa B; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Sural Nerve | 2005 |
Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy.
Topics: Alternative Splicing; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arginine; Blotting, Western; Cattle; Cells, Cultured; Collagen; Diabetic Nephropathies; DNA Primers; Endothelium, Vascular; Glycation End Products, Advanced; Humans; Immunohistochemistry; Immunoprecipitation; Kidney Cortex; Lysine; Male; Microscopy, Fluorescence; Molecular Weight; Peptidyl-Dipeptidase A; Ramipril; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Skin; Time Factors; Up-Regulation | 2005 |
The RAGE pathway in inflammatory myopathies and limb girdle muscular dystrophy.
Topics: Adult; Aged; Dermatomyositis; Glycation End Products, Advanced; Humans; Immunohistochemistry; Leukocytes, Mononuclear; Lysine; Middle Aged; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Dystrophies, Limb-Girdle; Myositis; NF-kappa B; Polymyositis; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Regeneration; Signal Transduction; Transcriptional Activation | 2005 |
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Ascorbic Acid; Blood Glucose; Chromatography, High Pressure Liquid; Creatine; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Heterocyclic Compounds, 3-Ring; Kidney; Lysine; Male; Oxidation-Reduction; Protease Inhibitors; Ramipril; Rats; Rats, Zucker; Spectrometry, Fluorescence | 2005 |
Immunohistochemical localization of advanced glycation end products in pinguecula.
Topics: Adult; Aged; Aging; Antibodies, Monoclonal; Arginine; Conjunctival Diseases; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Norleucine; Pyrroles | 2006 |
Labeling studies on the formation pathway of Nepsilon-carboxymethyllysine in maillard-type reactions.
Topics: Carbon Isotopes; Glycation End Products, Advanced; Lysine; Maillard Reaction; Models, Molecular | 2005 |
Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine.
Topics: Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycolysis; Humans; Lysine; Neoplasm Proteins; Neoplasms; Pyruvaldehyde | 2005 |
[Advanced glycation and oxidation products in patients with atherosclerosis].
Topics: Arteriosclerosis; Blood Proteins; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Oxidation-Reduction | 2005 |
Impaired left ventricular relaxation in type 2 diabetic rats is related to myocardial accumulation of N(epsilon)-(carboxymethyl) lysine.
Topics: Animals; Biomarkers; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Lysine; Male; Myocardial Contraction; Myocardium; Rats; Rats, Zucker; Severity of Illness Index; Ventricular Dysfunction, Left | 2006 |
Synthesis, tandem MS- and NMR-based characterization, and quantification of the carbon 13-labeled advanced glycation endproduct, 6-N-carboxymethyllysine.
Topics: Animals; Carbon Isotopes; Chromatography, High Pressure Liquid; Food Analysis; Glycation End Products, Advanced; Humans; Hydrogen; Lysine; Magnetic Resonance Spectroscopy; Tandem Mass Spectrometry | 2006 |
Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications p
Topics: Adult; Biopsy; Collagen; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Disease Progression; Disease Susceptibility; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Prognosis; Skin; Time Factors | 2005 |
Aminoguanidine and metformin prevent the reduced rate of HDL-mediated cell cholesterol efflux induced by formation of advanced glycation end products.
Topics: Albumins; Animals; Atherosclerosis; Cells, Cultured; Cholesterol, HDL; Diabetes Mellitus; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Humans; Hypoglycemic Agents; Lysine; Macrophages, Peritoneal; Metformin; Mice | 2006 |
Decreased levels of advanced glycation end-products in patients with Gilbert syndrome.
Topics: Bilirubin; Female; Gilbert Disease; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged | 2005 |
Elevation of Nepsilon-(carboxymethyl)lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosis.
Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Glycation End Products, Advanced; Humans; Hyaluronic Acid; Liver Cirrhosis; Lysine; Male; Middle Aged | 2006 |
Advanced glycation end product modification of bone proteins and bone remodelling: hypothesis and preliminary immunohistochemical findings.
Topics: Adult; Aged; Biopsy; Bone Remodeling; Female; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Osteoblasts; Osteoporosis; Osteoporosis, Postmenopausal; Protein Processing, Post-Translational | 2006 |
The receptor for advanced glycation end products is highly expressed in the skin and upregulated by advanced glycation end products and tumor necrosis factor-alpha.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Extracellular Matrix; Factor XIIIa; Female; Fibroblasts; Gene Expression; Glycation End Products, Advanced; HSP47 Heat-Shock Proteins; Humans; Leukocyte Common Antigens; Light; Lysine; Male; Metalloproteases; Middle Aged; Platelet Endothelial Cell Adhesion Molecule-1; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Skin; Skin Aging; Tumor Necrosis Factor-alpha; Up-Regulation | 2006 |
HNE-dependent molecular damage in diabetic nephropathy and its possible prevention by N-acetyl-cysteine and oxerutin.
Topics: Acetylcysteine; Aldehydes; Animals; Apoptosis; Cell Division; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycation End Products, Advanced; Hydroxyethylrutoside; Immunohistochemistry; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Rats; Rats, Wistar; Taurine | 2005 |
Gender-related differences in advanced glycation endproducts, oxidative stress markers and nitric oxide synthases in rats.
Topics: Animals; Female; Glycation End Products, Advanced; Hypertension; Immunohistochemistry; Kidney; Lysine; Male; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sex Characteristics; Transcription Factor RelA | 2006 |
Serum carboxymethyllysine predicts mortality in hemodialysis patients.
Topics: Adult; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Predictive Value of Tests; Renal Dialysis | 2006 |
Inhibition of advanced glycation end product formation on collagen by rutin and its metabolites.
Topics: Arginine; Chromatography, High Pressure Liquid; Collagen; Collagen Type I; Fluorescence; Glucose; Glycation End Products, Advanced; Lysine; Oxidation-Reduction; Rutin | 2006 |
Inhibition of apoptosis and reduction of intracellular pH decrease in retinal neural cell cultures by a blocker of carbonic anhydrase.
Topics: Animals; Annexin A5; Apoptosis; Carbonic Anhydrase Inhibitors; Caspase 3; Caspases; Cell Culture Techniques; Cell Survival; Flow Cytometry; Glyoxal; Hydrogen Peroxide; Hydrogen-Ion Concentration; In Situ Nick-End Labeling; Lysine; Neurons; Neuroprotective Agents; Pyruvaldehyde; Rats; Reactive Oxygen Species; Retina; Sulfonamides; Thiophenes | 2006 |
Site specificity of glycation and carboxymethylation of bovine serum albumin by fructose.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Fructose; Glucose; Glycation End Products, Advanced; Glycosylation; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Sensitivity and Specificity; Serum Albumin, Bovine; Temperature; Time Factors | 2006 |
Should we reconsider the advanced glycation end product issue in hemodialysis patients?
Topics: Glycation End Products, Advanced; Humans; Lysine; Renal Dialysis; Risk Factors | 2006 |
Oxidation and carboxy methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Blood Proteins; Case-Control Studies; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Imidazoles; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Neutrophils; Norleucine; Oxidative Stress; Protein Carbonylation; Pyrroles; Renal Dialysis; Respiratory Burst; Serum Albumin | 2005 |
Postprandial mononuclear NF-kappaB activation is independent of the AGE-content of a single meal.
Topics: Active Transport, Cell Nucleus; Administration, Oral; Caseins; Cell Nucleus; Diabetes Complications; Food, Formulated; Glycation End Products, Advanced; Humans; Leukocytes, Mononuclear; Lysine; Male; NF-kappa B; Vascular Diseases | 2006 |
Antioxidant tempol lowers age-related increases in insulin resistance in Fischer 344 rats.
Topics: Age Factors; Aging; Animals; Antioxidants; Biomarkers; Blood Glucose; Blood Proteins; Cyclic N-Oxides; Dietary Supplements; Homeostasis; Insulin; Insulin Resistance; Kidney Tubules, Proximal; Lysine; Male; Malondialdehyde; Models, Animal; Oxidative Stress; Rats; Rats, Inbred F344; Spin Labels; Triglycerides | 2006 |
Dose-dependent utilisation of casein-linked lysinoalanine, N(epsilon)-fructoselysine and N(epsilon)-carboxymethyllysine in rats.
Topics: Animals; Caseins; Diet; Dose-Response Relationship, Drug; Feces; Hot Temperature; Kidney; Liver; Lysine; Lysinoalanine; Maillard Reaction; Male; Rats; Rats, Wistar | 2006 |
Determination of N epsilon-(carboxymethyl)lysine in exhaled breath condensate using isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Aged; Biomarkers; Breath Tests; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Pneumonia; Pulmonary Disease, Chronic Obstructive; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2006 |
Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; C-Reactive Protein; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Inflammation Mediators; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; S100 Proteins; S100A12 Protein; Statistics as Topic | 2006 |
Circulating levels of Nepsilon-(carboxymethyl)lysine are increased in systemic sclerosis.
Topics: Adult; Aged; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Microcirculation; Microscopic Angioscopy; Middle Aged; Scleroderma, Systemic; Tunica Intima; Tunica Media | 2007 |
Concentrations of Nepsilon-carboxymethyllysine in human breast milk, infant formulas, and urine of infants.
Topics: Breast Feeding; Cesarean Section; Delivery, Obstetric; Enzyme-Linked Immunosorbent Assay; Female; Humans; Infant Formula; Infant, Newborn; Lysine; Maillard Reaction; Milk, Human | 2006 |
The receptor for advanced glycation end products and its ligands: a new inflammatory pathway in lung disease?
Topics: Airway Obstruction; Granuloma, Respiratory Tract; Humans; Immunohistochemistry; Ligands; Lung; Lung Diseases; Lung Diseases, Interstitial; Lung Neoplasms; Lysine; Nerve Growth Factors; Pneumonia; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Calcium Binding Protein beta Subunit; S100 Proteins; S100A12 Protein; Smoking | 2006 |
Advanced glycation end product deposits in climatic droplet keratopathy.
Topics: Antibodies, Monoclonal; Arginine; Cornea; Corneal Diseases; Cross-Linking Reagents; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Pyrroles | 2007 |
N(epsilon)-(carboxymethyl)lysine depositions in intramyocardial blood vessels in human and rat acute myocardial infarction: a predictor or reflection of infarction?
Topics: Aged; Animals; Coronary Vessels; E-Selectin; Endothelial Cells; Female; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Myocarditis; Oxidative Stress; Peroxidase; Prognosis; Rats; Risk Factors; Time Factors | 2006 |
Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711).
Topics: Animals; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Lysine; Mice; Mice, Mutant Strains; Thiazoles | 2006 |
The advanced glycation end product N(epsilon)-carboxymethyllysine is not a predictor of cardiovascular events and renal outcomes in patients with type 2 diabetic kidney disease and hypertension.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Female; Glycation End Products, Advanced; Humans; Hypertension; Lysine; Male; Middle Aged; Multivariate Analysis; Oxidative Stress; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Factors | 2006 |
Posttranslationally modified proteins as mediators of sustained intestinal inflammation.
Topics: Adult; Animals; Calgranulin A; Calgranulin B; Cell Extracts; Disease Models, Animal; Endothelial Cells; Female; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestines; Lysine; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2006 |
Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy?
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cytosol; Diabetes Mellitus, Experimental; Drug Synergism; Drug Therapy, Combination; Enzyme Activation; Glycation End Products, Advanced; Kidney; Lysine; Male; Mitochondria; NF-kappa B; Oxidative Stress; Protein Kinase C; Ramipril; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renin-Angiotensin System; Superoxide Dismutase; Thiazoles; Vascular Endothelial Growth Factor A | 2007 |
Effects of valsartan therapy on protein glycoxidation.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Arginine; Dinoprost; Female; Glycation End Products, Advanced; Glycosylation; Humans; Hypertension; Lysine; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Proteins; Tetrazoles; Valine; Valsartan | 2006 |
Mesothelial RAGE activation by AGEs enhances VEGF release and potentiates capillary tube formation.
Topics: Antibodies; Capillaries; Coculture Techniques; Endothelium; Endothelium, Vascular; Glucose; Glycation End Products, Advanced; Humans; Lysine; Neovascularization, Physiologic; Peritoneal Dialysis; Peritoneum; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin; Vascular Endothelial Growth Factor A | 2007 |
Evaluation of a gas chromatography/mass spectrometry method for the quantification of carboxymethyllysine in food samples.
Topics: Enzyme-Linked Immunosorbent Assay; Food Contamination; Gas Chromatography-Mass Spectrometry; Hot Temperature; Lysine; Maillard Reaction | 2007 |
Functioning of oxidative phosphorylation in liver mitochondria of high-fat diet fed rats.
Topics: Adenine Nucleotide Translocator 3; Adenosine Triphosphate; Animals; Diet; Dietary Fats; Glucose Intolerance; Liver; Lysine; Mitochondria, Liver; Oxidative Phosphorylation; Oxidative Stress; Rats | 2007 |
Endogenous secretory receptor for advanced glycation endproducts levels are correlated with serum pentosidine and CML in patients with type 1 diabetes.
Topics: Adolescent; Adult; Arginine; Diabetes Mellitus, Type 1; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Regression Analysis | 2007 |
Overproduction of N(epsilon)-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of aged rat.
Topics: Age Factors; Aging; Animals; Antibodies; Capillaries; Choroid; Choroidal Neovascularization; Glycation End Products, Advanced; Lysine; Macular Degeneration; Male; Organ Culture Techniques; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2007 |
Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-A(y)/Ta mice.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glycation End Products, Advanced; Immunohistochemistry; Laminin; Lysine; Male; Mice; Pyridoxamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schiff Bases; Transforming Growth Factor beta1; Tyrosine | 2007 |
Maillard reaction indicators in diets usually consumed by adolescent population.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Chromatography, High Pressure Liquid; Color; Diet; Food Analysis; Food Handling; Food Preferences; Furaldehyde; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Spectrometry, Fluorescence | 2007 |
Simultaneous determination of the advanced glycation end product N (epsilon)-carboxymethyllysine and its precursor, lysine, in exhaled breath condensate using isotope-dilution-hydrophilic-interaction liquid chromatography coupled to tandem mass spectromet
Topics: Adult; Breath Tests; Calibration; Chromatography, Liquid; Female; Humans; Isotopes; Lysine; Male; Middle Aged; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2007 |
Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice.
Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Cardiomyopathies; Dexamethasone; Doxorubicin; Glycation End Products, Advanced; Hydroxyethylrutoside; Immunohistochemistry; Ketoprofen; Lysine; Male; Mice; Mice, Inbred BALB C; Myocytes, Cardiac | 2007 |
Pravastatin inhibits carboxymethyllysine-induced monocyte chemoattractant protein 1 expression in podocytes via prevention of signalling events.
Topics: Animals; Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Drug Combinations; Gene Expression; Lysine; Mice; Podocytes; Pravastatin; Signal Transduction | 2007 |
Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies?
Topics: Aged; Alcoholism; Biomarkers; Biopsy; Diabetes Complications; Humans; Leukocytes, Mononuclear; Lysine; Middle Aged; Peripheral Nerves; Polyneuropathies; Predictive Value of Tests; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Schwann Cells; Signal Transduction; Sural Nerve; Transcription Factor RelA; Vasculitis; Vitamin B 12 Deficiency | 2007 |
Carbonyl and oxidative stress in patients with breast cancer--is there a relation to the stage of the disease?
Topics: Blood Proteins; Breast Neoplasms; Case-Control Studies; Estrogens; Female; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Neoplasm Staging; Oxidation-Reduction; Oxidative Stress; Prognosis; Protein Carbonylation; Receptor, ErbB-2 | 2007 |
Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; C-Reactive Protein; Diet; Dinoprost; Energy Intake; Female; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lysine; Male; Middle Aged; Oxidative Stress; Pyruvaldehyde | 2007 |
Kinetics of formation of three indicators of the maillard reaction in model cookies: influence of baking temperature and type of sugar.
Topics: Carbohydrates; Cooking; Edible Grain; Gas Chromatography-Mass Spectrometry; Kinetics; Lysine; Maillard Reaction | 2007 |
Advanced glycation endproducts: a biomarker for age as an outcome predictor after cardiac surgery?
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Coronary Artery Bypass; Glycation End Products, Advanced; Heart; Humans; Lysine; Middle Aged; Pericardial Effusion; Predictive Value of Tests; Treatment Outcome | 2007 |
Hypochlorous acid generates N epsilon-(carboxymethyl)lysine from Amadori products.
Topics: Acetaldehyde; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Humans; Hydrogen-Ion Concentration; Hypochlorous Acid; Lysine; Neutrophils; Oxidation-Reduction; Serum Albumin | 2007 |
Advanced glycation end products and the absence of premature atherosclerosis in glycogen storage disease Ia.
Topics: Adolescent; Adult; Arginine; Atherosclerosis; Carotid Arteries; Collagen; Female; Glycation End Products, Advanced; Glycogen Storage Disease Type I; Humans; Lysine; Male; Oxidative Stress; Risk; Skin; Tunica Intima; Tunica Media | 2007 |
Unchanged serum levels of advanced glycation endproducts in patients with liver disease.
Topics: Adult; Aged; Aged, 80 and over; Fatty Liver; Female; Glycation End Products, Advanced; Hepatitis C; Humans; Imidazoles; Lysine; Male; Middle Aged; Renal Insufficiency | 2007 |
Markers of endothelial activity are related to components of the metabolic syndrome, but not to circulating concentrations of the advanced glycation end-product N epsilon-carboxymethyl-lysine in healthy Swedish men.
Topics: Alcohol Drinking; Biomarkers; Cohort Studies; E-Selectin; Endothelium, Vascular; Feeding Behavior; Glycation End Products, Advanced; Humans; Inflammation; Insulin; Insulin Resistance; Intercellular Adhesion Molecule-1; Lysine; Male; Metabolic Syndrome; Middle Aged; Oxidative Stress; Risk Factors; Sweden; Vascular Cell Adhesion Molecule-1 | 2007 |
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.
Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Biomarkers; Cell Differentiation; Citric Acid Cycle; Cysteine; Diabetes Complications; Diabetes Mellitus, Type 2; Fibroblasts; Fumarates; Humans; Insulin Resistance; Lysine; Mice; Mitochondria; Obesity; Protein Processing, Post-Translational; Risk Factors; Stress, Physiological; Succinic Acid; Sulfhydryl Compounds | 2007 |
Amount of N(omega)-(Carboxymethyl)arginine generated in collagen and bovine serum albumin during glycation reactions is significantly different.
Topics: Animals; Arginine; Cattle; Collagen Type I; Glucose; Glycation End Products, Advanced; Lysine; Ribose; Serum Albumin, Bovine | 2007 |
Identification of CML-modified proteins in hemofiltrate of diabetic patients by proteome analysis.
Topics: Antibodies; Antibodies, Monoclonal; Antibody Specificity; Blood Proteins; Diabetes Mellitus; Electrophoresis, Gel, Two-Dimensional; Glycation End Products, Advanced; Glycosylation; Hemofiltration; Humans; Immunoblotting; Lysine; Proteome; Sequence Analysis, Protein | 2008 |
Immunohistochemical study of N-epsilon-carboxymethyl lysine (CML) in human brain: relation to vascular dementia.
Topics: Aged; Aged, 80 and over; Blood Vessels; Brain; Dementia, Vascular; Female; Humans; Longitudinal Studies; Lysine; Male; Middle Aged; Neurons; Neuropsychological Tests; Severity of Illness Index; Statistics, Nonparametric | 2007 |
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glomerular Mesangium; Glycation End Products, Advanced; Lysine; Male; NADPH Oxidases; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Superoxides | 2008 |
Clinical and prognostic value of advanced glycation end-products in chronic heart failure.
Topics: Aged; Biomarkers; Female; Follow-Up Studies; Glycation End Products, Advanced; Heart Failure; Humans; Lysine; Male; Middle Aged; Prognosis; Risk Assessment; Risk Factors; Survival Analysis | 2007 |
Simultaneous analysis of lysine, Nepsilon-carboxymethyllysine and lysinoalanine from proteins.
Topics: Acetamides; Chromatography, Gas; Eggs; Fluoroacetates; Food Analysis; Infant Food; Lysine; Lysinoalanine; Maillard Reaction; Organosilicon Compounds; Proteins | 2007 |
AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Antioxidants; Cell Line; Chromones; Down-Regulation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glycation End Products, Advanced; Humans; Lysine; Morpholines; Mutation; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyruvaldehyde; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; RNA, Small Interfering; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Superoxide Dismutase; Transfection | 2008 |
The ligand activity of AGE-proteins to scavenger receptors is dependent on their rate of modification by AGEs.
Topics: Aldehydes; Animals; Cattle; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Crystallins; Glycation End Products, Advanced; Humans; Ligands; Lysine; Macrophages; Mice; Receptors, Scavenger; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Distribution | 2007 |
Fluorescent serum and urinary advanced glycoxidation end-products in non- diabetic subjects.
Topics: Adult; Aged; Body Composition; Case-Control Studies; Chromatography, High Pressure Liquid; Diet; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Lipoproteins; Lysine; Male; Middle Aged; Spectrometry, Fluorescence | 2007 |
N epsilon-(carboxymethyl)lysine during the early development of hypertension.
Topics: Albuminuria; Animals; Blood Pressure; Creatinine; Glycation End Products, Advanced; Heart Rate; Humans; Hypertension; Lysine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2008 |
Some natural compounds enhance N epsilon-(carboxymethyl)lysine formation.
Topics: Glucosides; Humans; Kinetics; Lipid Peroxidation; Lysine; Maillard Reaction; Oleanolic Acid; Pentacyclic Triterpenes; Phenols; Quercetin; Triterpenes | 2008 |
Usefulness of antibodies for evaluating the biological significance of AGEs.
Topics: Aldehydes; Antibodies; Arginine; Glycation End Products, Advanced; Lysine | 2008 |
Nepsilon-(carboxymethyl)lysine, a major advanced glycation end product in exhaled breath condensate as a biomarker of small airway involvement in asthma.
Topics: Adult; Asthma; Biomarkers; Breath Tests; Bronchi; Exhalation; Female; Glycation End Products, Advanced; Humans; Lysine; Male | 2007 |
Advanced glycation end products accumulate in the reproductive tract of men with diabetes.
Topics: Adult; Blotting, Western; Case-Control Studies; Diabetes Complications; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epididymis; Glycation End Products, Advanced; Humans; Immunohistochemistry; Infertility, Male; Lysine; Male; Semen; Spermatozoa; Testis | 2009 |
Immunochemical detection of Nepsilon-(carboxyethyl)lysine using a specific antibody.
Topics: Aldehydes; Animals; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Cattle; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Kidney; Lysine; Male; Pyruvaldehyde; Rats; Rats, Wistar; Sensitivity and Specificity; Serum Albumin | 2008 |
Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation.
Topics: Adult; Aged; Case-Control Studies; Cells, Cultured; Cross-Sectional Studies; Endothelial Cells; Endothelium, Vascular; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Hyperemia; Lysine; Male; Middle Aged; Nitric Oxide Synthase Type III; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Regional Blood Flow; Renal Insufficiency, Chronic; RNA Interference; RNA, Messenger; RNA, Small Interfering; Severity of Illness Index; Skin; Up-Regulation | 2008 |
N(epsilon)-carboxymethyllysine-modified proteins are unable to bind to RAGE and activate an inflammatory response.
Topics: Cell Line; Epithelial Cells; Gene Expression; Glutathione Transferase; Glycosylation; Glyoxylates; Humans; Inflammation; Interleukin-6; Interleukin-8; Lactoglobulins; Lysine; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Serum Albumin; Tumor Necrosis Factor-alpha | 2008 |
Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats.
Topics: Animals; Aorta; Dietary Carbohydrates; Fructose; Glutathione; Glycation End Products, Advanced; Hydrogen Peroxide; Hypertension; Hypoglycemic Agents; Lysine; Male; Mesenteric Arteries; Metformin; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Sprague-Dawley | 2008 |
Glutaraldehyde is an effective cross-linker for production of antibodies against advanced glycation end-products.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Glutaral; Glycation End Products, Advanced; Humans; Lysine; Mice; Serum Albumin | 2008 |
Increased serum advanced glycation end-products is a distinct finding in lean women with polycystic ovary syndrome (PCOS).
Topics: Adult; Body Mass Index; Case-Control Studies; Female; Glycation End Products, Advanced; Humans; Insulin Resistance; Lysine; Polycystic Ovary Syndrome; Sensitivity and Specificity; Thinness; Up-Regulation; Waist-Hip Ratio; Young Adult | 2008 |
Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies.
Topics: Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glycated Serum Albumin; Glycation End Products, Advanced; Guanidines; Lysine; Male; Proteinuria; Pyrones; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin; Streptozocin; Transcription Factor RelA | 2008 |
Determination of Nepsilon-(carboxymethyl)lysine in food systems by ultra performance liquid chromatography-mass spectrometry.
Topics: Animals; Bread; Chromatography, High Pressure Liquid; Food Analysis; Lysine; Meat; Milk; Tandem Mass Spectrometry | 2009 |
Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Brain; Cerebrovascular Circulation; Child; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Rats; Rats, Wistar | 2008 |
Cardiac troponin T and advanced glycation end-products in hemodialysis patients.
Topics: Adolescent; Adult; Arginine; Calcium; Child; Child, Preschool; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Infant; Lysine; Male; Renal Dialysis; Troponin T | 2008 |
Determination of N epsilon-(carboxymethyl)lysine in foods and related systems.
Topics: Diet; Food Analysis; Glycation End Products, Advanced; Humans; Lysine | 2008 |
Plasma concentration and urinary excretion of N epsilon-(carboxymethyl)lysine in breast milk- and formula-fed infants.
Topics: Female; Humans; Infant; Infant Formula; Lysine; Maillard Reaction; Milk, Human; Mothers | 2008 |
Induction of heat shock proteins and the proteasome system by casein-N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)lysine in Caco-2 cells.
Topics: Adenocarcinoma; Blotting, Western; Caco-2 Cells; Caseins; Cell Line, Tumor; Colonic Neoplasms; Glycation End Products, Advanced; Humans; Lysine; Mass Spectrometry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2008 |
Maillard products as biomarkers in cancer.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cytoplasm; Female; Glycolysis; Humans; Immunohistochemistry; Lysine; Maillard Reaction; Neoplasm Invasiveness | 2008 |
Evidence against nitric oxide-quenching effects of chemically defined Maillard reaction products.
Topics: Amino Acids; Edetic Acid; Glycation End Products, Advanced; Lysine; Maillard Reaction; Nitric Oxide; Nitric Oxide Donors; Protein Binding; S-Nitroso-N-Acetylpenicillamine; Serum Albumin, Bovine; Solutions | 2008 |
Plasma N-epsilon-(carboxymethyl)lysine levels are associated with the extent of vessel injury after coronary arterial stenting.
Topics: Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; C-Reactive Protein; Catheterization; Female; Follow-Up Studies; Humans; Logistic Models; Lysine; Male; Middle Aged; Predictive Value of Tests; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Stents; Treatment Outcome | 2008 |
Renal N(epsilon)-carboxymethyllysine deposition after kidney transplantation.
Topics: Animals; Biopsy; Humans; Inflammation; Kidney; Kidney Transplantation; Kidney Tubules; Low Density Lipoprotein Receptor-Related Protein-2; Lysine; Male; Oxidative Stress; Rats; Rats, Inbred F344; Rats, Inbred Lew; Species Specificity | 2008 |
Formation of lipid oxidation and isomerization products during processing of nuts and sesame seeds.
Topics: Arachis; Food Handling; Hot Temperature; Isomerism; Lipid Peroxidation; Lysine; Nuts; Pistacia; Prunus; Seeds; Sesamum; Sterilization; Thiobarbituric Acid Reactive Substances; Trans Fatty Acids | 2008 |
Identification of AGE-precursors and AGE formation in glycation-induced BSA peptides.
Topics: Amino Acid Sequence; Glycation End Products, Advanced; Glycolipids; Glycosides; Glycosylation; Imidazoles; Lysine; Models, Biological; Norleucine; Pyrroles; Schiff Bases; Serum Albumin, Bovine; Spectrometry, Mass, Electrospray Ionization | 2008 |
Severity of diabetic microvascular complications is associated with a low soluble RAGE level.
Topics: Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2008 |
Skin autofluorescence is increased in systemic lupus erythematosus but is not reflected by elevated plasma levels of advanced glycation endproducts.
Topics: Adult; Case-Control Studies; Female; Fluorescence; Glycation End Products, Advanced; Humans; Lupus Erythematosus, Systemic; Lysine; Male; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Severity of Illness Index; Skin; Vascular Cell Adhesion Molecule-1 | 2008 |
Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines.
Topics: Aging; Animals; Aorta; Collagen; Dogs; Drug Evaluation, Preclinical; Elastin; Glycation End Products, Advanced; Heart Ventricles; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles; Vasa Vasorum; Vascular Resistance; Ventricular Function, Left | 2008 |
Antiglycative and anti-VEGF effects of s-ethyl cysteine and s-propyl cysteine in kidney of diabetic mice.
Topics: Albuminuria; Animals; Arginine; Blood Glucose; Creatinine; Cysteine; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Kidney; Lysine; Male; Mice; Mice, Inbred BALB C; Organ Size; Vascular Endothelial Growth Factor A | 2008 |
Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patients.
Topics: Age Factors; Arginine; Cardiac Volume; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Echocardiography; Echocardiography, Doppler; Echocardiography, Doppler, Color; Female; Fluorescence; Glycation End Products, Advanced; Heart Failure, Diastolic; Humans; Lysine; Male; Middle Aged; Myocardial Contraction; Renal Dialysis; Risk Factors; Sex Factors; Skin; Stroke Volume; Tandem Mass Spectrometry; Ventricular Dysfunction; Ventricular Function; Ventricular Pressure | 2008 |
What is the influence of renal function on the prognostic value of advanced glycation end-products and sRAGE in heart failure?
Topics: Biomarkers; Creatinine; Glomerular Filtration Rate; Glycation End Products, Advanced; Heart Failure; Humans; Kidney; Lysine; Prognosis; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors | 2008 |
Advanced glycation end products and their circulating receptors and level of kidney function in older community-dwelling women.
Topics: Aged; Aged, 80 and over; Biomarkers; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney; Lysine; Models, Statistical; Multivariate Analysis; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Residence Characteristics; Signal Transduction | 2009 |
Modification of collagen in vitro with respect to formation of Nepsilon-carboxymethyllysine.
Topics: Amino Acids; Biomimetics; Biopolymers; Collagen; Glucuronic Acid; Lysine; Mass Spectrometry; Molecular Structure; Spectroscopy, Fourier Transform Infrared | 2009 |
Advanced glycation end products in pregnancies complicated with diabetes mellitus or preeclampsia.
Topics: Adult; Biomarkers; Case-Control Studies; Diabetes, Gestational; Dinoprost; Female; Ferric Compounds; Glycation End Products, Advanced; Humans; Lysine; Oxidative Stress; Pre-Eclampsia; Pregnancy; Pregnancy in Diabetics; Vitamin E; Young Adult | 2008 |
Association between serum carboxymethyl-lysine, a dominant advanced glycation end product, and anemia in adults: the Baltimore longitudinal study of aging.
Topics: Adult; Aging; Anemia; Baltimore; Female; Humans; Longitudinal Studies; Lysine; Male | 2008 |
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with increased aortic pulse wave velocity in adults.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aorta; Exercise Test; Female; Follow-Up Studies; Glycation End Products, Advanced; Heart Rate; Humans; Lysine; Male; Middle Aged; Prognosis; Prospective Studies; Reference Values; Risk Factors; Vascular Resistance | 2009 |
Carboxymethyl-lysine, an advanced glycation end product, and decline of renal function in older community-dwelling adults.
Topics: Aged; Aged, 80 and over; Chronic Disease; Cross-Sectional Studies; Educational Status; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney Diseases; Kidney Function Tests; Logistic Models; Longitudinal Studies; Lysine; Male; Mental Status Schedule; Odds Ratio; Sex Characteristics; Smoking | 2009 |
Concentrations of receptor for advanced glycation end products, VEGF and CML in plasma, follicular fluid, and peritoneal fluid in women with and without endometriosis.
Topics: Ascitic Fluid; Endometriosis; Female; Follicular Fluid; Glycation End Products, Advanced; Humans; Lysine; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Vascular Endothelial Growth Factor A | 2008 |
Advanced glycation end products increase transglutaminase activity in primary porcine tenocytes.
Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glycation End Products, Advanced; Lysine; RNA, Messenger; Stifle; Swine; Tendons; Tetrazolium Salts; Thiazoles; Transglutaminases | 2009 |
Analysis of advanced glycation endproducts in dairy products by isotope dilution liquid chromatography-electrospray tandem mass spectrometry. The particular case of carboxymethyllysine.
Topics: Animals; Chromatography, Liquid; Glycation End Products, Advanced; Humans; Hydrolysis; Lysine; Milk; Peptide Hydrolases; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry | 2009 |
Elevated serum advanced glycation end products and poor grip strength in older community-dwelling women.
Topics: Aged; Aged, 80 and over; Aging; Disability Evaluation; Female; Glycation End Products, Advanced; Humans; Lysine; Muscle Strength; Muscle Weakness; Prognosis; Women's Health | 2009 |
Specific local cardiovascular changes of Nepsilon-(carboxymethyl)lysine, vascular endothelial growth factor, and Smad2 in the developing embryos coincide with maternal diabetes-induced congenital heart defects.
Topics: Animals; Congenital Abnormalities; Disease Models, Animal; Embryo, Mammalian; Female; Glycation End Products, Advanced; Heart Defects, Congenital; Humans; Infant, Newborn; Lysine; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Sprague-Dawley; Risk Factors; Smad2 Protein; Vascular Endothelial Growth Factor A; Wound Healing | 2009 |
Elevated serum advanced glycation end products and their circulating receptors are associated with anaemia in older community-dwelling women.
Topics: Activities of Daily Living; Age Factors; Aged; Aged, 80 and over; Anemia; Baltimore; Biomarkers; Cross-Sectional Studies; Disability Evaluation; Female; Glycation End Products, Advanced; Hemoglobins; Humans; Logistic Models; Lysine; Odds Ratio; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Assessment; Risk Factors; Up-Regulation | 2009 |
Elevation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in patients presenting with acute myocardial infarction.
Topics: Acute Disease; Aged; Female; Glycosides; Humans; Lysine; Male; Middle Aged; Myocardial Infarction; Oxidation-Reduction | 2009 |
Advanced glycation end products regulate extracellular matrix protein and protease expression by human glomerular mesangial cells.
Topics: alpha-Macroglobulins; Antibodies; Blotting, Northern; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix Proteins; Flavonoids; Flow Cytometry; Gene Expression; Glycation End Products, Advanced; Humans; Lysine; Matrix Metalloproteinase 2; Mesangial Cells; Norleucine; Oligonucleotide Array Sequence Analysis; Plasminogen Activator Inhibitor 1; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinase-3; Tissue Plasminogen Activator | 2009 |
Letter by Hartog et al. regarding article, "Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines".
Topics: Animals; Arginine; Collagen; Cross-Linking Reagents; Dogs; Glycation End Products, Advanced; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles | 2009 |
The amelioration of streptozotocin diabetes-induced renal damage by Wu-Ling-San (Hoelen Five Herb Formula), a traditional Chinese prescription.
Topics: Albuminuria; Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drugs, Chinese Herbal; Fibronectins; Glycation End Products, Advanced; Hypoglycemic Agents; Kidney; Lysine; Magnoliopsida; Male; Mitochondria; NF-kappa B; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta1 | 2009 |
Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration.
Topics: Aged; Aged, 80 and over; Arginine; Autoantibodies; Biomarkers; Blood Proteins; Case-Control Studies; Chromatography, Liquid; Female; Fluorometry; Humans; Logistic Models; Lysine; Macular Degeneration; Male; Mass Spectrometry; Middle Aged; Pyrroles | 2009 |
Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women.
Topics: Aged; Aging; Cardiovascular Diseases; Diabetes Mellitus; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Predictive Value of Tests; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renal Insufficiency; Residence Characteristics; Risk Factors | 2009 |
Mechanical ventilation during experimental sepsis increases deposition of advanced glycation end products and myocardial inflammation.
Topics: Animals; Cardiomyopathies; Glycation End Products, Advanced; Immunohistochemistry; Inflammation; Lysine; Male; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Sepsis | 2009 |
Naturally occurring flavonoids attenuate high glucose-induced expression of proinflammatory cytokines in human monocytic THP-1 cells.
Topics: Cells, Cultured; Cyclooxygenase 2; Cytokines; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Hyperglycemia; Lysine; Monocytes; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transcription Factor RelA | 2009 |
Novel application of surface plasmon resonance biosensor chips for measurement of advanced glycation end products in serum of Zucker diabetic fatty rats.
Topics: Animals; Enzyme-Linked Immunosorbent Assay; Equipment Design; Glycation End Products, Advanced; Lysine; Male; Protein Array Analysis; Rats; Rats, Zucker; Sensitivity and Specificity; Surface Plasmon Resonance | 2009 |
Effect of N-epsilon-(carboxymethyl)lysine on coronary vasoconstriction in isolated perfused hearts from control and streptozotocin-induced diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channels; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Disease Models, Animal; Drug Synergism; Glycation End Products, Advanced; In Vitro Techniques; Lysine; Male; Rats; Rats, Wistar; Stimulation, Chemical; Streptozocin; Superoxides; Vasoconstriction | 2009 |
Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study.
Topics: Aged; Aortic Aneurysm, Abdominal; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus; Down-Regulation; Humans; Logistic Models; Lysine; Male; Men's Health; Odds Ratio; Risk Assessment; Risk Factors; Western Australia | 2009 |
Astragalosides isolated from the root of astragalus radix inhibit the formation of advanced glycation end products.
Topics: Arginine; Astragalus Plant; Diabetes Complications; Glycation End Products, Advanced; Lysine; Plant Extracts; Plant Roots; Saponins; Triterpenes | 2009 |
Plasma carboxymethyl-lysine, an advanced glycation end product, and all-cause and cardiovascular disease mortality in older community-dwelling adults.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Cause of Death; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Prospective Studies | 2009 |
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase.
Topics: Adult; Arginase; Arteries; Case-Control Studies; Cells, Cultured; Endothelium, Vascular; Female; Glutathione Peroxidase; Glutathione Reductase; Humans; Lactoylglutathione Lyase; Lysine; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Pre-Eclampsia; Pregnancy; Pyruvaldehyde; Scavenger Receptors, Class E; Thiolester Hydrolases | 2009 |
Editorial: A recipe for inflammation.
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Lysine; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin | 2009 |
Matcha, a powdered green tea, ameliorates the progression of renal and hepatic damage in type 2 diabetic OLETF rats.
Topics: Animals; Biomarkers; Blood Proteins; Camellia sinensis; Cholesterol; Diabetes Complications; Diabetes Mellitus, Experimental; Glucose; Glycation End Products, Advanced; Kidney; Liver; Lysine; Phytotherapy; Plant Extracts; Powders; Rats; Rats, Inbred OLETF; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin; Sterol Regulatory Element Binding Protein 2; Tea; Thiobarbiturates; Triglycerides | 2009 |
Characterization of anti-advanced glycation end product antibodies to nonenzymatically lysine-derived and arginine-derived glycated products.
Topics: Animals; Antibodies; Arginine; Cattle; Cross Reactions; Glycation End Products, Advanced; Lysine; Rabbits; Serum Albumin, Bovine | 2009 |
Relationship of an advanced glycation end product, plasma carboxymethyl-lysine, with slow walking speed in older adults: the InCHIANTI study.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Community Health Planning; Female; Glycation End Products, Advanced; Humans; Logistic Models; Lysine; Male; Muscle Strength; Odds Ratio; Walking | 2010 |
High plasma levels of the soluble receptor for advanced glycation endproducts in patients with symptomatic carotid atherosclerosis.
Topics: Aged; Aged, 80 and over; Atherosclerosis; C-Reactive Protein; Carotid Artery Diseases; Carotid Artery, Common; Carotid Stenosis; Enzyme-Linked Immunosorbent Assay; Female; Fibrinogen; Glycation End Products, Advanced; Humans; Immunohistochemistry; Linear Models; Lysine; Male; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2009 |
Influence of insulin and muscle fiber type in nepsilon-(carboxymethyl)-lysine accumulation in soleus muscle of rats with streptozotocin-induced diabetes mellitus.
Topics: Animals; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Image Processing, Computer-Assisted; Insulin; Lysine; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Rats; Rats, Sprague-Dawley | 2009 |
Serum carboxymethyl-lysine, a dominant advanced glycation end product, is associated with chronic kidney disease: the Baltimore longitudinal study of aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; Baltimore; Chronic Disease; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney Diseases; Linear Models; Longitudinal Studies; Lysine; Male; Middle Aged; Racial Groups; Smoking | 2010 |
Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels.
Topics: Aged; Blotting, Western; Cohort Studies; Creatine; Enzyme-Linked Immunosorbent Assay; Female; Gene Frequency; Glycation End Products, Advanced; Humans; Kidney Function Tests; Lysine; Male; Middle Aged; Netherlands; Phenotype; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2009 |
Differences in mouse models of diabetes mellitus in studies of male reproduction.
Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA Damage; Epididymis; Glycation End Products, Advanced; Infertility, Male; Lysine; Male; Mice; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Spermatozoa; Streptozocin; Testis | 2010 |
Inhibitory effect of the Cree traditional medicine wiishichimanaanh (Vaccinium vitis-idaea) on advanced glycation endproduct formation: identification of active principles.
Topics: Chromatography, High Pressure Liquid; Flavonoids; Fruit; Glycation End Products, Advanced; Lysine; Medicine, Traditional; Phenols; Plant Extracts; Vaccinium vitis-idaea | 2010 |
Plasma sRAGE is not associated with urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage.
Topics: Age of Onset; Aged; Albuminuria; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Lipids; Lysine; Male; Middle Aged; Patient Selection; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2010 |
AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.
Topics: Active Transport, Cell Nucleus; Age Factors; Animals; Cell Line; Endothelial Cells; ErbB Receptors; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADP; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphorylation; Protein Kinase C-delta; Protein Subunits; Pyruvaldehyde; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; Signal Transduction; Time Factors; Transcription Factor RelA; Transfection; Vascular Diseases | 2010 |
Carboxymethylation of the fibrillar collagen with respect to formation of hydroxyapatite.
Topics: Alkylation; Amino Acids; Biomimetics; Borohydrides; Collagen; Crystallization; Glucose; Glucuronic Acid; Glyoxylates; Hydroxyapatites; Indicators and Reagents; Lysine; Methylation; Microfibrils; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Minerals; Spectroscopy, Fourier Transform Infrared | 2010 |
Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction.
Topics: Animals; Aspartic Acid Endopeptidases; Benzofurans; Blood Glucose; Body Weight; Coronary Vessels; Diabetes Mellitus, Experimental; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glycopeptides; Heart; Lipids; Lysine; Male; Metalloendopeptidases; Myocardium; Oligopeptides; Organ Size; Organophosphonates; Peptides, Cyclic; Perfusion; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Thiorphan; Vasoconstriction | 2010 |
Involvement of advanced glycation end-products, pentosidine and N(epsilon)-(carboxymethyl)lysine, in doxorubicin-induced cardiomyopathy in rats.
Topics: Animals; Antineoplastic Agents; Arginine; Blood Glucose; Cardiomyopathies; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Immunohistochemistry; Lysine; Male; Rats | 2010 |
Association between serum levels of the soluble receptor (sRAGE) for advanced glycation endproducts (AGEs) and their receptor (RAGE) in peripheral blood mononuclear cells of children with type 1 diabetes mellitus.
Topics: Adolescent; Child; Cholesterol, LDL; Diabetes Mellitus, Type 1; Female; Humans; Hypochlorous Acid; Leukocytes, Mononuclear; Lysine; Male; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2009 |
Formation of N(epsilon)-(carboxymethyl)lysine and loss of lysine in casein glucose-fatty acid model systems.
Topics: Animals; Caseins; Cattle; Fatty Acids; Glucose; Lysine; Models, Chemical | 2010 |
Increased levels of N(epsilon)-(carboxymethyl)lysine in epithelial lining fluid from peripheral airways in patients with chronic obstructive pulmonary disease: a pilot study.
Topics: Aged; Bronchioles; Bronchoscopy; Dinoprost; Forced Expiratory Volume; Humans; Interleukin-8; Lysine; Middle Aged; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa; Smoking; Specimen Handling; Vital Capacity | 2010 |
Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy.
Topics: Aged; Antibodies, Neutralizing; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Female; HMGB1 Protein; Humans; Ligands; Lysine; Male; Middle Aged; Molecular Weight; Protein Kinase C-alpha; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Transcription, Genetic | 2010 |
Combined immunoelectron microscopic and computer-assisted image analyses to detect advanced glycation end-products in human myocardium.
Topics: Colloids; Coronary Artery Bypass; Female; Glycation End Products, Advanced; Gold; Humans; Image Processing, Computer-Assisted; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Myocardium; Particle Size; Surface Properties | 2010 |
Advanced glycation end products on stored red blood cells increase endothelial reactive oxygen species generation through interaction with receptor for advanced glycation end products.
Topics: Adolescent; Adult; Aged; Blood Preservation; Cell Communication; Cells, Cultured; Endothelial Cells; Erythrocyte Transfusion; Erythrocytes; Flow Cytometry; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Time Factors; Umbilical Veins; Young Adult | 2010 |
Effects of heat-processed ginseng and its active component ginsenoside 20(S)-Rg3 on the progression of renal damage and dysfunction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty rats.
Topics: Animals; Antioxidants; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Ginsenosides; Glycation End Products, Advanced; Hypoglycemic Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Lipids; Lysine; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Panax; Phytotherapy; Plant Extracts; Proteinuria; Rats; Rats, Inbred OLETF; Thiobarbituric Acid Reactive Substances | 2010 |
Circulating glycolaldehyde induces oxidative damage in the kidney of rats.
Topics: Acetaldehyde; Animals; Catalase; Enzyme-Linked Immunosorbent Assay; Injections, Intraventricular; Kidney; Lactoylglutathione Lyase; Lipid Peroxidation; Lysine; Male; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase | 2010 |
N(ɛ)-(carboxymethyl)lysine linkage to α-synuclein and involvement of advanced glycation end products in α-synuclein deposits in an MPTP-intoxicated mouse model.
Topics: alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Glycation End Products, Advanced; Lysine; Mice; Mice, Inbred C57BL; MPTP Poisoning; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase | 2010 |
Maternally transmitted and food-derived glycotoxins: a factor preconditioning the young to diabetes?
Topics: Adiponectin; Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Infant; Infant Food; Infant, Newborn; Insulin; Isoprostanes; Lysine; Pyruvaldehyde; Risk Factors; Young Adult | 2010 |
Glycolaldehyde induces oxidative stress in the heart: a clue to diabetic cardiomyopathy?
Topics: Acetaldehyde; Animals; Cardiomyopathies; Catalase; Diabetes Complications; Injections, Intravenous; Lactoylglutathione Lyase; Lipid Peroxidation; Lysine; Male; Myocardium; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Time Factors | 2010 |
Glycoxidative stress-induced mitophagy modulates mitochondrial fates.
Topics: Animals; Cattle; Cell Death; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Hyperglycemia; Insulinoma; Lysine; Mice; Mitochondria; Models, Biological; Oxidative Stress; Phagosomes; Rats; Reactive Oxygen Species; Serum Albumin | 2010 |
Regarding "Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study".
Topics: Aortic Aneurysm, Abdominal; Biomarkers; Diabetes Mellitus; Down-Regulation; Humans; Lysine; Male; Men's Health; Predictive Value of Tests | 2010 |
Inhibition of advanced glycation end product formation by medicinal plant extracts correlates with phenolic metabolites and antioxidant activity.
Topics: Antioxidants; Canada; Free Radical Scavengers; Glycation End Products, Advanced; Lysine; Malondialdehyde; Oxidation-Reduction; Phenols; Plant Extracts; Plants, Medicinal; Time Factors | 2011 |
Relationship of a dominant advanced glycation end product, serum carboxymethyl-lysine, and abnormal glucose metabolism in adults: the Baltimore Longitudinal Study of Aging.
Topics: Aged; Baltimore; Blood Glucose; Diabetes Mellitus; Female; Glucose Intolerance; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Logistic Models; Lysine; Male; Middle Aged | 2010 |
Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice.
Topics: Animals; Biomarkers; Body Weight; Cholesterol; Cornus; Cyclooxygenase 2; Diabetes Mellitus, Type 2; Drinking; Fatty Acids; Gene Expression Regulation, Enzymologic; Glucose; Glycation End Products, Advanced; Hematologic Tests; Inflammation; Iridoids; Kidney; Lipid Metabolism; Liver; Lysine; Male; Mice; Nitric Oxide Synthase Type II; Organ Size; Oxidative Stress; PPAR alpha; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Transcription Factor RelA; Triglycerides | 2010 |
Relationship between advanced glycation end products and increased lipid peroxidation in semen of diabetic men.
Topics: Adult; Antioxidants; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Infertility, Male; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Semen; Spermatozoa; Thiobarbituric Acid Reactive Substances; Young Adult | 2011 |
Immunochemical and mass spectrometric analysis of Nε-(carboxymethyl)lysine content of AGE-BSA systems prepared with and without selected antiglycation agents.
Topics: Animals; Cattle; Chemistry Techniques, Analytical; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Immunochemistry; Lysine; Mass Spectrometry; Serum Albumin, Bovine | 2010 |
Diagnostic potential of plasma carboxymethyllysine and carboxyethyllysine in multiple sclerosis.
Topics: Adult; Biomarkers; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Multiple Sclerosis; Recurrence; Severity of Illness Index | 2010 |
Effect of inhibitor compounds on Nε-(carboxymethyl)lysine (CML) and Nε-(carboxyethyl)lysine (CEL) formation in model foods.
Topics: Food Analysis; Food Handling; Lysine | 2010 |
AGE-RAGE in multiple sclerosis brain.
Topics: Adult; Alzheimer Disease; Brain; Case-Control Studies; Female; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Multiple Sclerosis; Pilot Projects; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2011 |
Differential effects of advanced glycation end-products on renal tubular cell inflammation.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Chemokine CCL2; Connective Tissue Growth Factor; Epithelial Cells; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Inflammation Mediators; Interleukin-6; Kidney Tubules, Proximal; Lysine; Nephritis, Interstitial; NF-kappa B; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Rosiglitazone; Serum Albumin; Serum Albumin, Bovine; Signal Transduction; Thiazolidinediones; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2011 |
Circulating levels and dietary intake of the advanced glycation end-product marker carboxymethyl lysine in chronic kidney disease patients on conservative predialysis therapy: a pilot study.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; C-Reactive Protein; Case-Control Studies; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diet; Energy Intake; Female; Glycation End Products, Advanced; Humans; Inflammation; Interleukin-6; Kidney Failure, Chronic; Lysine; Male; Malnutrition; Middle Aged; Nutrition Assessment; Pilot Projects; Regression Analysis; Renal Dialysis; Risk Factors | 2011 |
Natural compounds containing a catechol group enhance the formation of Nε-(carboxymethyl)lysine of the Maillard reaction.
Topics: Animals; Catechols; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Free Radicals; Glutathione Peroxidase; Glycation End Products, Advanced; Glycosylation; Humans; Hydrogen Peroxide; Lysine; Macrophages; Maillard Reaction; Male; Mice; Mice, Inbred A; Oxidation-Reduction; Serum Albumin; Streptozocin; Structure-Activity Relationship | 2011 |
Advanced glycation end-products accumulation compromises embryonic development and achievement of pregnancy by assisted reproductive technology.
Topics: Aging; Arginine; Embryo Implantation; Embryonic Development; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Follicular Fluid; Glycation End Products, Advanced; Humans; Infertility; Lysine; Ovulation Induction; Pregnancy; Pregnancy Rate; Reproductive Techniques, Assisted; Retrospective Studies | 2011 |
Mapping the glycoxidation product Nε-carboxymethyllysine in the milk proteome.
Topics: Animals; Cattle; Electrophoresis, Gel, Two-Dimensional; Glycosylation; Immunoblotting; Lysine; Milk; Milk Proteins; Protein Processing, Post-Translational; Proteome; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2011 |
Elevated Nε-(carboxymethyl)lysine is associated with apoptosis of retinal pericytes in streptozotocin-induced diabetic rats.
Topics: Animals; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Fluorescent Antibody Technique, Indirect; Glycation End Products, Advanced; In Situ Nick-End Labeling; Lysine; NF-kappa B; Pericytes; Rats; Rats, Sprague-Dawley; Retinal Vessels | 2011 |
Endogenous secretory receptor for advanced glycation end products is associated with low serum interleukin-1 receptor antagonist and elevated IL-6 in older community-dwelling adults.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-18; Interleukin-1beta; Interleukin-6; Italy; Longitudinal Studies; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Interleukin-6; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Young Adult | 2011 |
Oxidative damage in the liver of rats treated with glycolaldehyde.
Topics: Acetaldehyde; Animals; Catalase; Fatty Liver; Glycation End Products, Advanced; Injections, Intravenous; Lactoylglutathione Lyase; Lipid Peroxidation; Liver; Liver Cirrhosis; Lysine; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2011 |
Protective role of adiponectin on endothelial dysfunction induced by AGEs: a clinical and experimental approach.
Topics: Adiponectin; Adult; Cells, Cultured; Diabetes Mellitus, Type 2; E-Selectin; Endothelial Cells; Endothelium, Vascular; Female; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Insulin Resistance; Lysine; Male; Middle Aged; Vascular Cell Adhesion Molecule-1 | 2011 |
An autoantibody against N(ε)-(carboxyethyl)lysine (CEL): possible involvement in the removal of CEL-modified proteins by macrophages.
Topics: Animals; Arginine; Autoantibodies; Glycation End Products, Advanced; Humans; Lysine; Macrophages, Peritoneal; Mice; Rabbits; Serum Albumin | 2011 |
Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study.
Topics: Aged; Arginine; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Male; Middle Aged | 2011 |
Spermatogenic and sperm quality differences in an experimental model of metabolic syndrome and hypogonadal hypogonadism.
Topics: Animals; Dietary Fats; Disease Models, Animal; DNA Fragmentation; Epididymis; Glycation End Products, Advanced; Gonadotropin-Releasing Hormone; Hyperglycemia; Hypogonadism; Lysine; Male; Metabolic Syndrome; Rabbits; Random Allocation; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Semen Analysis; Spermatogenesis; Spermatozoa; Testis; Triptorelin Pamoate | 2011 |
Advanced glycation end products (AGEs) increase human mesangial foam cell formation by increasing Golgi SCAP glycosylation in vitro.
Topics: alpha-Mannosidase; Blotting, Western; Cells, Cultured; Cholesterol; Endoplasmic Reticulum; Foam Cells; Glomerular Mesangium; Glycation End Products, Advanced; Glycosylation; Golgi Apparatus; Humans; Hydroxymethylglutaryl CoA Reductases; Intracellular Signaling Peptides and Proteins; Lysine; Membrane Proteins; Microscopy, Confocal; Microsomes; Plasmids; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger | 2011 |
UV B-irradiation enhances the racemization and isomerizaiton of aspartyl residues and production of Nε-carboxymethyl lysine (CML) in keratin of skin.
Topics: Aged; Aged, 80 and over; Animals; Antibodies; Blotting, Western; D-Aspartic Acid; Glycation End Products, Advanced; Humans; Immunohistochemistry; Keratins; Lysine; Mice; Proteomics; Skin; Stereoisomerism; Ultraviolet Rays | 2011 |
Temporal increases in urinary carboxymethyllysine correlate with albuminuria development in diabetes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Albuminuria; Animals; Biomarkers; Cytosol; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Gene Expression; Glomerular Filtration Rate; Glycation End Products, Advanced; Kidney Cortex; Lysine; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Streptozocin; Time Factors | 2011 |
RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes.
Topics: Animals; Apoptosis; Calcium; Cell Proliferation; Cells, Cultured; Humans; Lysine; Mice; Muscle, Smooth, Vascular; NFATC Transcription Factors; Proto-Oncogene Proteins c-pim-1; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; STAT3 Transcription Factor | 2011 |
The presence of N(ε)-(Carboxymethyl) lysine in the human epidermis.
Topics: Abdomen; Adult; Aged; Amino Acid Sequence; Epidermis; Female; Glycation End Products, Advanced; Humans; Immunoblotting; Lysine; Male; Middle Aged; Molecular Sequence Data; Proteins; Skin; Spectrometry, Mass, Electrospray Ionization; Young Adult | 2011 |
Association of sVAP-1, sRAGE, and CML with lactation-induced insulin sensitivity in young non-diabetic healthy women.
Topics: Adult; Amine Oxidase (Copper-Containing); Cell Adhesion Molecules; Cohort Studies; Female; Humans; Insulin Resistance; Lactation; Lysine; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reference Values | 2011 |
AGE formation blockade with aminoguanidine does not ameliorate chronic allograft nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cardiotonic Agents; Dinoprost; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Hydroxyproline; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Lysine; Male; Oxidative Stress; Proteinuria; Rats; Rats, Inbred F344; Rats, Inbred Lew; Tetrazoles; Time Factors; Transplantation, Homologous | 2011 |
Fat mass is inversely associated with serum carboxymethyl-lysine, an advanced glycation end product, in adults.
Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Body Composition; Cohort Studies; Cross-Sectional Studies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged | 2011 |
Dietary intake associated with serum versus urinary carboxymethyl-lysine, a major advanced glycation end product, in adults: the Energetics Study.
Topics: Adult; Aged; Atherosclerosis; Diabetes Mellitus; Diet; Female; Glycation End Products, Advanced; Humans; Kidney Diseases; Lysine; Male; Middle Aged; Young Adult | 2012 |
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis.
Topics: Aged; Biomarkers; Biopsy; Cytokines; Enzyme Inhibitors; Fatty Liver; Female; Gene Expression; Guanidines; Hep G2 Cells; Hepatocytes; Humans; In Vitro Techniques; Liver; Lysine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Pyridoxamine; Vitamin B Complex | 2012 |
N(ɛ)-(carboxymethyl)lysine modification of elastin alters its biological properties: implications for the accumulation of abnormal elastic fibers in actinic elastosis.
Topics: Adult; Elastic Tissue; Elastin; Humans; Leukocyte Elastase; Lysine; Male; Microscopy, Electron, Scanning; Muramidase; Skin Aging; Sunlight; Ultraviolet Rays | 2012 |
Study of the urinary and faecal excretion of Nε-carboxymethyllysine in young human volunteers.
Topics: Adolescent; Child; Diet; Feces; Food Handling; Humans; Lysine; Maillard Reaction; Male; Nitrogen | 2012 |
Ω3-Polyunsaturated fatty acids prevent lipoperoxidation, modulate antioxidant enzymes, and reduce lipid content but do not alter glycogen metabolism in the livers of diabetic rats fed on a high fat thermolyzed diet.
Topics: Adiposity; Animals; Catalase; Diabetes Mellitus, Experimental; Diet, High-Fat; Fatty Acids, Omega-3; Glycation End Products, Advanced; Glycogen; Lipid Metabolism; Lipid Peroxidation; Liver; Lysine; Male; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Two fluorescent wavelengths, 440(ex)/520(em) nm and 370(ex)/440(em) nm, reflect advanced glycation and oxidation end products in human skin without diabetes.
Topics: Adult; Arginine; Collagen; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Methionine; Middle Aged; Oxidative Stress; Skin; Skin Aging; Spectrometry, Fluorescence | 2012 |
Development of monoclonal antibodies specific for glycated prion protein.
Topics: Animals; Antibodies, Monoclonal; Arginine; Brain; Glycosylation; Humans; Hybridomas; Lysine; Mice; Mice, Knockout; Mice, Transgenic; Peptides; Prion Diseases; Prions; Recombinant Proteins | 2011 |
Ellagic acid, a new antiglycating agent: its inhibition of Nϵ-(carboxymethyl)lysine.
Topics: Animals; Crystallins; Diabetes Complications; Ellagic Acid; Gluconates; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lactones; Lens, Crystalline; Lysine; Male; Muramidase; Organ Culture Techniques; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Enzyme Activation; Glycation End Products, Advanced; Humans; Inflammation; Lysine; Memory Disorders; Mice; Mice, Knockout; Neurons; Oxidation-Reduction; Protein Multimerization; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides | 2011 |
Advanced glycation end products contribute to the immunogenicity of IFN-β pharmaceuticals.
Topics: Adult; Animals; Antibodies, Neutralizing; CHO Cells; Cricetinae; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Female; Glycation End Products, Advanced; Glycosylation; Haptens; Humans; Imidazoles; Immunotherapy; Interferon-beta; Lysine; Male; Multiple Sclerosis, Relapsing-Remitting; Protein Processing, Post-Translational; Recombinant Proteins | 2012 |
Advanced glycation end-products as markers of aging and longevity in the long-lived Ansell's mole-rat (Fukomys anselli).
Topics: Aging; Animals; Arginine; Biomarkers; Collagen; Female; Glycation End Products, Advanced; Longevity; Lysine; Male; Mole Rats; Skin | 2012 |
Formation of early and advanced Maillard reaction products correlates to the ripening of cheese.
Topics: Caseins; Cheese; Chymosin; Food Handling; Food Technology; Lysine; Maillard Reaction; Protein Modification, Translational; Pyruvaldehyde; Time Factors | 2012 |
Decreased plasma sRAGE levels in COPD: influence of oxygen therapy.
Topics: Aged; Biomarkers; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Oxidative Stress; Oxygen Inhalation Therapy; Pulmonary Disease, Chronic Obstructive; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Respiratory Function Tests; Time Factors | 2012 |
The associations of advanced glycation end products and its soluble receptor with pancreatic cancer risk: a case-control study within the prospective EPIC Cohort.
Topics: Adult; Aged; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pancreatic Neoplasms; Prognosis; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2012 |
An explorative analysis of secretory receptor for advanced glycation endproducts in primary focal segmental glomerulosclerosis.
Topics: Adolescent; Adult; Case-Control Studies; Female; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental; Humans; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Regression Analysis; Young Adult | 2012 |
Advanced glycation end-product Nε-carboxymethyl-Lysine accelerates progression of atherosclerotic calcification in diabetes.
Topics: Alkaline Phosphatase; Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; Blotting, Western; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Core Binding Factor Alpha 2 Subunit; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diet, High-Fat; Disease Progression; Glucose; Immunohistochemistry; Injections, Intravenous; Lipoproteins, LDL; Lysine; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteogenesis; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Staining and Labeling; Time Factors; Vascular Calcification | 2012 |
Circulating selenium and carboxymethyl-lysine, an advanced glycation endproduct, are independent predictors of anemia in older community-dwelling adults.
Topics: Aged; Aged, 80 and over; Aging; Anemia; Biomarkers; Cohort Studies; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Incidence; Italy; Longitudinal Studies; Lysine; Male; Oxidative Stress; Predictive Value of Tests; Prevalence; Proportional Hazards Models; Selenium | 2012 |
Peripheral RAGE (receptor for advanced glycation endproducts)-ligands in normal pregnancy and preeclampsia: novel markers of inflammatory response.
Topics: Adult; Biomarkers; Disease Progression; Female; Follow-Up Studies; HMGB1 Protein; Humans; Inflammation; Inflammation Mediators; Ligands; Lysine; Pre-Eclampsia; Pregnancy; Pregnancy Trimesters; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Proteins; S100A12 Protein | 2012 |
Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study.
Topics: Adolescent; Adult; Antibody Specificity; Autoantibodies; Child; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Population Surveillance; Radioimmunoprecipitation Assay; Twins, Dizygotic; Twins, Monozygotic; Young Adult | 2012 |
Cinnamic acid and its derivatives inhibit fructose-mediated protein glycation.
Topics: Animals; Cattle; Cinnamates; Down-Regulation; Fructose; Glycation End Products, Advanced; Glycosylation; In Vitro Techniques; Lysine; Oxidation-Reduction; Protein Carbonylation; Serum Albumin, Bovine | 2012 |
Advanced glycation end product Nε-carboxymethyllysine induces endothelial cell injury: the involvement of SHP-1-regulated VEGFR-2 dephosphorylation.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Gene Silencing; Glycation End Products, Advanced; Human Umbilical Vein Endothelial Cells; Humans; Lysine; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Plasma glycation levels are associated with severity in sepsis.
Topics: Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Kidney Diseases; Lysine; Male; Middle Aged; Prognosis; ROC Curve; Sepsis | 2012 |
Aristolochic acid-induced accumulation of methylglyoxal and Nε-(carboxymethyl)lysine: an important and novel pathway in the pathogenic mechanism for aristolochic acid nephropathy.
Topics: Animals; Aristolochic Acids; Creatine; Disease Models, Animal; Female; Kidney; Lysine; Mice; Mice, Inbred C3H; Nephritis, Interstitial; Pyruvaldehyde | 2012 |
The alternative crosstalk between RAGE and nitrative thioredoxin inactivation during diabetic myocardial ischemia-reperfusion injury.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Free Radical Scavengers; Imines; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide Synthase Type II; Organometallic Compounds; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Small Interfering; Salicylates; Superoxides; Thioredoxins; Tyrosine | 2012 |
The effects of low-dose nepsilon-(carboxymethyl)lysine (CML) and nepsilon-(carboxyethyl)lysine (CEL), two main glycation free adducts considered as potential uremic toxins, on endothelial progenitor cell function.
Topics: Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Glycation End Products, Advanced; Humans; Lysine; Mitogen-Activated Protein Kinases; Neovascularization, Physiologic; Phosphorylation; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Stem Cells; Time Factors; Toxins, Biological; Uremia | 2012 |
Reduced soluble receptor for advanced glycation end-products (sRAGE) scavenger capacity precedes pre-eclampsia in Type 1 diabetes.
Topics: Adult; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique; Glycation End Products, Advanced; Humans; Imidazoles; Linear Models; Lysine; Pre-Eclampsia; Pregnancy; Pregnancy in Diabetics; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2012 |
Okara promoted acrylamide and carboxymethyl-lysine formation in bakery products.
Topics: Acrylamide; Cooking; Dietary Fiber; Flour; Food Analysis; Furaldehyde; Lysine; Maillard Reaction; Plant Proteins; Polysaccharides; Soy Foods | 2012 |
Formation and inhibition of Nε-(carboxymethyl)lysine in saccharide-lysine model systems during microwave heating.
Topics: Antioxidants; Ascorbic Acid; Glucose; Glycation End Products, Advanced; Lysine; Microwaves; Quercetin; Rutin; Thiamine; Tocopherols | 2012 |
Reduction of paraoxonase-1 activity may contribute the qualitative impairment of HDL particles in patients with type 2 diabetes.
Topics: Aged; Apolipoprotein A-I; Aryldialkylphosphatase; Atherosclerosis; Biological Transport; Biomarkers; Cell Line; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hyperglycemia; Lipoproteins, HDL; Lysine; Macrophages; Male; Middle Aged; Serum Amyloid A Protein | 2013 |
The role of advanced glycation end-products and their receptor on outcome in heart failure patients with preserved and reduced ejection fraction.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Female; Glycation End Products, Advanced; Heart Failure; Humans; Kaplan-Meier Estimate; Lysine; Male; Mass Spectrometry; Middle Aged; Predictive Value of Tests; Proportional Hazards Models; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Severity of Illness Index; Stroke Volume | 2012 |
Digestibility of extruded proteins and metabolic transit of N ε -carboxymethyllysine in rats.
Topics: Animals; Caseins; Cooking; Diet; Dietary Proteins; Digestion; Feces; Food Handling; Lysine; Lysinoalanine; Maillard Reaction; Rats; Rats, Wistar; Weight Gain | 2013 |
Maternal plasma advanced glycation end products concentrations in response to oral 50-gram glucose load in mid-pregnancy: a pilot study.
Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Female; Glucose; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Hyperglycemia; Lysine; Mass Spectrometry; Pilot Projects; Pregnancy; Pregnancy Trimester, Second; Prospective Studies; Pyruvaldehyde | 2012 |
Diastolic dysfunction of aging is independent of myocardial structure but associated with plasma advanced glycation end-product levels.
Topics: Adult; Aged; Aging; Blood Chemical Analysis; Collagen; Coronary Artery Disease; Diastole; Echocardiography; Glycation End Products, Advanced; Hemodynamics; Humans; Lysine; Male; Middle Aged; Myocardium; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Ventricular Dysfunction, Left | 2012 |
The receptor for advanced glycation end products mediates lung endothelial activation by RBCs.
Topics: Animals; Endothelial Cells; Endothelium, Vascular; Erythrocyte Transfusion; Erythrocytes; HEK293 Cells; HMGB1 Protein; Humans; Lung; Lysine; Mice; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Vascular Cell Adhesion Molecule-1 | 2013 |
Advanced glycation end products in infant formulas do not contribute to insulin resistance associated with their consumption.
Topics: Breast Feeding; Cohort Studies; Cross-Sectional Studies; Diet; Female; Glycation End Products, Advanced; Humans; Infant; Infant Formula; Inflammation; Insulin Resistance; Lysine; Male; Milk, Human; Oxidative Stress | 2013 |
Soluble receptor for advanced glycation end products and risk of liver cancer.
Topics: Aged; Carcinoma, Hepatocellular; Finland; Glycation End Products, Advanced; Humans; Liver Neoplasms; Lysine; Male; Middle Aged; Randomized Controlled Trials as Topic; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors | 2013 |
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels | 2013 |
Role of N-ε- carboxy methyl lysine, advanced glycation end products and reactive oxygen species for the development of nonproliferative and proliferative retinopathy in type 2 diabetes mellitus.
Topics: Adult; Aged; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycation End Products, Advanced; Humans; Leukocytes, Mononuclear; Lysine; Male; Middle Aged; Reactive Oxygen Species; Sulfhydryl Compounds; Vitreous Body | 2013 |
Metabolic transit of N(ε)-carboxymethyl-lysine after consumption of AGEs from bread crust.
Topics: Animal Feed; Animals; Bone and Bones; Bread; Feces; Female; Glycation End Products, Advanced; Lysine; Male; Rats; Rats, Wistar | 2013 |
Biodistribution and elimination study of fluorine-18 labeled Nε-carboxymethyl-lysine following intragastric and intravenous administration.
Topics: Administration, Intravenous; Animals; Cell Line; Fluorine Radioisotopes; Hep G2 Cells; Humans; Lysine; Male; Mice; Positron-Emission Tomography; Tissue Distribution | 2013 |
Total plasma Nε-(carboxymethyl)lysine and sRAGE levels are inversely associated with a number of metabolic syndrome risk factors in non-diabetic young-to-middle-aged medication-free subjects.
Topics: Adolescent; Adult; Aged; Cohort Studies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Metabolic Syndrome; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; Serum Albumin; Young Adult | 2014 |
Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure.
Topics: Adolescent; Adult; Blood Pressure; Body Mass Index; Female; Glycation End Products, Advanced; Humans; Leukocytes, Mononuclear; Lipids; Lysine; Male; Middle Aged; Transcription Factor RelA; Waist-Hip Ratio; Young Adult | 2014 |
Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts.
Topics: Diabetes Mellitus; Glycation End Products, Advanced; Isotope Labeling; Lysine; Mass Spectrometry; Norleucine; Pyrroles | 2013 |
Plasma sRAGE and N-(carboxymethyl) lysine in patients with CHF and/or COPD.
Topics: Aged; Biomarkers; Case-Control Studies; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Heart Failure; Humans; Lysine; Male; Natriuretic Peptide, Brain; Peptide Fragments; Pulmonary Disease, Chronic Obstructive | 2013 |
Parainflammation associated with advanced glycation endproduct stimulation of RPE in vitro: implications for age-related degenerative diseases of the eye.
Topics: Cell Survival; Cells, Cultured; Chemokine CXCL11; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Inflammation; Keratins; Lysine; Macular Degeneration; Pigment Epithelium of Eye; Postmortem Changes; Reproducibility of Results; Retinal Drusen; Serum Albumin, Bovine; Tissue Donors; Up-Regulation | 2013 |
N-ε-fructosyllysine and N-ε-carboxymethyllysine, but not lysinoalanine, are available for absorption after simulated gastrointestinal digestion.
Topics: Caseins; Chromatography, Gel; Digestion; Glycoproteins; Hydrogen-Ion Concentration; Intestinal Absorption; Lysine; Lysinoalanine; Models, Biological; Proteolysis | 2014 |
Increased circulating advanced glycation endproducts (AGEs) in acute trauma patients.
Topics: Acute Disease; Adult; Female; Glycation End Products, Advanced; Humans; Intensive Care Units; Kinetics; Longitudinal Studies; Lysine; Male; Middle Aged; Pyruvaldehyde; Severity of Illness Index; Wounds and Injuries | 2014 |
Pentosidine determination in CSF: a potential biomarker of Alzheimer's disease?
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lysine; Male; Middle Aged; Peptide Fragments | 2014 |
Plasma advanced glycation end-products and skin autofluorescence are increased in COPD.
Topics: Aged; Arginine; Case-Control Studies; Female; Fluorescence; Glycation End Products, Advanced; Humans; Inflammation; Lung; Lysine; Male; Middle Aged; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Skin; Smoking; Spirometry | 2014 |
The accumulation of the glycoxidation product N(ε)-carboxymethyllysine in cardiac tissues with age, diabetes mellitus and coronary heart disease.
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Coronary Artery Disease; Diabetes Mellitus; Female; Glycosylation; Humans; Infant; Lysine; Male; Middle Aged; Myocardium; Oxidation-Reduction; Smoking; Young Adult | 2013 |
N-Epsilon-(carboxymethyl)lysine is unable to induce endothelial dysfunction but is able to attenuate Ages-induced endothelium damage in human umbilical vein endothelial cells.
Topics: Acridine Orange; Adult; Algorithms; Apoptosis; Data Interpretation, Statistical; Endothelial Cells; Endothelium, Vascular; Ethidium; Female; Fluorescence Polarization; Glycation End Products, Advanced; Humans; Intercellular Adhesion Molecule-1; Lysine; Pregnancy; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta1; Umbilical Veins | 2013 |
N(ε)-Carboxymethyllysine (CML), a Maillard reaction product, stimulates serotonin release and activates the receptor for advanced glycation end products (RAGE) in SH-SY5Y cells.
Topics: Calcium; Cell Line, Tumor; Humans; Lysine; Maillard Reaction; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Serotonin; Serotonin; Signal Transduction; Transcriptional Activation; Up-Regulation | 2013 |
Plasma levels of advanced glycation endproducts Nε-(carboxymethyl)lysine, Nε-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: the Hoorn and CODAM studies.
Topics: Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Lysine; Male; Middle Aged | 2013 |
Peroxisome proliferator-activated receptor-γ activators monascin and rosiglitazone attenuate carboxymethyllysine-induced fibrosis in hepatic stellate cells through regulating the oxidative stress pathway but independent of the receptor for advanced glycat
Topics: Animals; Anti-Inflammatory Agents; beta-Glucans; Cells, Cultured; Hepatic Stellate Cells; Heterocyclic Compounds, 3-Ring; Liver Cirrhosis; Lysine; Male; Mice; Oxidative Stress; PPAR gamma; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Small Interfering; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transfection | 2013 |
Simultaneous analysis of Nε-(carboxymethyl)lysine, reducing sugars, and lysine during the dairy thermal process.
Topics: Animals; Chromatography, Ion Exchange; Galactose; Glucose; Lactose; Lysine; Maillard Reaction; Milk | 2013 |
Advanced glycation end products promote hepatosteatosis by interfering with SCAP-SREBP pathway in fructose-drinking mice.
Topics: Animals; Drinking; Fatty Liver; Fructose; Glucose; Glucose Intolerance; Glycation End Products, Advanced; Hypoglycemia; Intracellular Signaling Peptides and Proteins; Lipids; Liver; Lysine; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Triglycerides | 2013 |
Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression.
Topics: Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Experimental; Echocardiography; Fibrosis; Inflammation; Lactoylglutathione Lyase; Lysine; Myocardium; Oxidative Stress; Rats; Tandem Mass Spectrometry; Ventricular Remodeling | 2013 |
Dietary consumption of meat, fat, animal products and advanced glycation end-products and the risk of Barrett's oesophagus.
Topics: Adult; Aged; Aged, 80 and over; Barrett Esophagus; Case-Control Studies; Diet; Female; Glycation End Products, Advanced; Humans; Logistic Models; Lysine; Male; Meat; Middle Aged; Odds Ratio | 2013 |
Hydroxyl radical induced by lipid in Maillard reaction model system promotes diet-derived N(ε)-carboxymethyllysine formation.
Topics: Chromatography, High Pressure Liquid; Diet; Food Handling; Glyoxal; Hydroxyl Radical; Linoleic Acid; Lipid Metabolism; Lysine; Maillard Reaction; Models, Biological; Oleic Acid; Triolein | 2013 |
Isotope dilution ESI-LC-MS/MS for quantification of free and total Nε-(1-Carboxymethyl)-L-Lysine and free Nε-(1-Carboxyethyl)-L-Lysine: comparison of total Nε-(1-Carboxymethyl)-L-Lysine levels measured with new method to ELISA assay in gruel samples.
Topics: Beverages; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Isotope Labeling; Lysine; Tandem Mass Spectrometry | 2013 |
Small- and large-fiber neuropathy after 40 years of type 1 diabetes: associations with glycemic control and advanced protein glycation: the Oslo Study.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Follow-Up Studies; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Nerve Fibers; Pyruvaldehyde; Sensory Thresholds; Young Adult | 2013 |
Graptopetalum paraguayense and resveratrol ameliorates carboxymethyllysine (CML)-induced pancreas dysfunction and hyperglycemia.
Topics: Animals; Crassulaceae; Gallic Acid; Homeodomain Proteins; Hyperglycemia; Insulin; Liver; Lysine; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Pancreas; Plant Extracts; PPAR gamma; Resveratrol; Stilbenes; Taiwan; Trans-Activators | 2013 |
Suppression of dimerumic acid on hepatic fibrosis caused from carboxymethyl-lysine (CML) by attenuating oxidative stress depends on Nrf2 activation in hepatic stellate cells (HSCs).
Topics: Actins; Animals; Antioxidants; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Diketopiperazines; Gene Expression Regulation; Gene Knockdown Techniques; Hepatic Stellate Cells; Hydroxamic Acids; Liver Cirrhosis; Lysine; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; Oxidative Stress | 2013 |
Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Biomarkers; Cardiac Rehabilitation; Cardiovascular Diseases; Disabled Persons; Female; Follow-Up Studies; Frail Elderly; Health Status; Humans; Incidence; Lysine; Male; Prevalence; Prognosis; Retrospective Studies; United States | 2014 |
Plasma levels of advanced glycation endproducts are associated with type 1 diabetes and coronary artery calcification.
Topics: Adult; Arginine; Biomarkers; C-Reactive Protein; Case-Control Studies; Chromatography, High Pressure Liquid; Coronary Artery Disease; Coronary Vessels; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pyrimidines; Tomography, X-Ray Computed; Vascular Calcification; Vascular Cell Adhesion Molecule-1; von Willebrand Factor | 2013 |
The influence of disease and age on human cardiac stem cells.
Topics: Adolescent; Adult; Age Factors; Aged; Cells, Cultured; Child; Child, Preschool; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Flow Cytometry; Humans; Infant; Lysine; Middle Aged; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-kit; Stem Cells; Young Adult | 2014 |
Quantitative determination of ɛ-N-carboxymethyl-L-lysine in human plasma by liquid chromatography-tandem mass spectrometry.
Topics: Biomarkers; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus; Diabetic Angiopathies; Humans; Limit of Detection; Lysine; Oxidative Stress; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Uremia | 2014 |
Association of peripheral neuropathy with circulating advanced glycation end products, soluble receptor for advanced glycation end products and other risk factors in patients with type 2 diabetes.
Topics: Aged; Arterial Occlusive Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Neuropathies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Paris; Peripheral Nervous System; Prevalence; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; Severity of Illness Index; Sex Factors; Solubility; Waist Circumference | 2014 |
Acrylamide, 5-hydroxymethylfurfural and N(ε)-carboxymethyl-lysine in coffee substitutes and instant coffees.
Topics: Acrylamide; Coffee; Food Analysis; Food Contamination; Furaldehyde; Lysine; Reproducibility of Results | 2014 |
Activation of the receptor for advanced glycation end products induces nuclear inhibitor of protein phosphatase-1 suppression.
Topics: Animals; Apoptosis; Case-Control Studies; Cell Cycle Checkpoints; Cell Enlargement; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Diabetic Nephropathies; Down-Regulation; Endoribonucleases; Glycation End Products, Advanced; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mice; Necrosis; NF-kappa B; Phosphoprotein Phosphatases; Podocytes; Receptor for Advanced Glycation End Products; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering; Serum Albumin, Bovine | 2014 |
Serum carboxymethyllysine, an advanced glycation end product, and age-related macular degeneration: the Age, Gene/Environment Susceptibility-Reykjavik Study.
Topics: Age Factors; Aged; Aged, 80 and over; Cross-Sectional Studies; Disease Susceptibility; Enzyme-Linked Immunosorbent Assay; Female; Gene-Environment Interaction; Glycation End Products, Advanced; Humans; Iceland; Logistic Models; Lysine; Macular Degeneration; Male; Prevalence; Risk Factors; Visual Acuity | 2014 |
Effects of Nε-carboxymethyl-Lysine on ERS-mediated apoptosis in diabetic atherosclerosis.
Topics: Animals; Apoptosis; Atherosclerosis; Blood Glucose; Blotting, Western; Cholesterol; Diabetes Mellitus, Experimental; Endoplasmic Reticulum Stress; Glycation End Products, Advanced; Immunohistochemistry; Lysine; Male; Mice | 2014 |
Diffuse glomerular nodular lesions in diabetic pigs carrying a dominant-negative mutant hepatocyte nuclear factor 1-alpha, an inheritant diabetic gene in humans.
Topics: Animals; Animals, Genetically Modified; Collagen; Diabetes Mellitus; Genes, Dominant; Glycation End Products, Advanced; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Immunohistochemistry; Inheritance Patterns; Kidney Glomerulus; Lysine; Mutation; Sus scrofa; Transforming Growth Factor beta | 2014 |
Acute insulin resistance mediated by advanced glycation endproducts in severely burned rats.
Topics: Animals; Blood Glucose; Burns; Cell Line; Glucose Tolerance Test; Glycation End Products, Advanced; Glycogen Synthase Kinase 3; Hyperglycemia; Insulin; Insulin Resistance; Kaplan-Meier Estimate; Lysine; Phosphorylation; Positron-Emission Tomography; Prospective Studies; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley | 2014 |
Advanced glycation end products are associated with arterial stiffness in type 1 diabetes.
Topics: Adult; Aorta; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Linear Models; Lysine; Male; Middle Aged; Optical Imaging; Pulse Wave Analysis; Skin; Spectrometry, Fluorescence; Vascular Stiffness | 2014 |
Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties.
Topics: Aldehyde Reductase; alpha-Glucosidases; Amyloid; Animals; Apigenin; Artemisia; Enzyme Inhibitors; Fructosamine; Glucosides; Glycation End Products, Advanced; Glycoside Hydrolase Inhibitors; Lens, Crystalline; Lysine; Oxidation-Reduction; Plants, Medicinal; Protein Carbonylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats, Sprague-Dawley; Serum Albumin, Bovine | 2014 |
Nε-(carboxymethyl)lysine-receptor for advanced glycation end product axis is a key modulator of obesity-induced dysregulation of adipokine expression and insulin resistance.
Topics: Adipokines; Adipose Tissue; Adult; Animals; Cells, Cultured; Female; Humans; Insulin Resistance; Lipid Metabolism; Lysine; Male; Mice; Mice, Inbred C57BL; Middle Aged; Obesity; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2014 |
Investigation of variations in the acrylamide and N(ε) -(carboxymethyl) lysine contents in cookies during baking.
Topics: Acrylamide; Antioxidants; Bread; Chromatography, Liquid; Cooking; Diet; Food Contamination; Hot Temperature; Humans; Lysine; Maillard Reaction; Mass Spectrometry | 2014 |
Advanced glycation/glycoxidation endproduct carboxymethyl-lysine and incidence of coronary heart disease and stroke in older adults.
Topics: Aged; Albumins; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Cohort Studies; Coronary Disease; Creatinine; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Immunoassay; Incidence; Lysine; Male; Oxidative Stress; Proportional Hazards Models; Stroke; Treatment Outcome | 2014 |
Circulating levels of carboxy‐methyl‐lysine (CML) are associated with hip fracture risk: the Cardiovascular Health Study.
Topics: Age Factors; Aged; Female; Follow-Up Studies; Glycation End Products, Advanced; Hip Fractures; Humans; Incidence; Lysine; Male; Prospective Studies; Retrospective Studies; Risk Factors | 2014 |
An advanced glycation end product (AGE)-rich diet promotes Nε-carboxymethyl-lysine accumulation in the cardiac tissue and tendons of rats.
Topics: Animals; Female; Glucose; Glycation End Products, Advanced; Humans; Lysine; Male; Myocardium; Rats; Rats, Wistar; Tendons | 2014 |
Nε-carboxymethyllysine-mediated endoplasmic reticulum stress promotes endothelial cell injury through Nox4/MKP-3 interaction.
Topics: Animals; Apoptosis; Cell Line, Transformed; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Dual Specificity Phosphatase 6; Endoplasmic Reticulum Stress; Endothelial Cells; Gene Expression Regulation; Humans; Lysine; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; NADPH Oxidase 4; NADPH Oxidases; Protein Binding; RNA, Small Interfering; Signal Transduction | 2014 |
Increased serum concentrations of pentosidine are related to presence and severity of coronary artery disease.
Topics: Aged; Area Under Curve; Arginine; Biomarkers; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Cross-Sectional Studies; Female; Glycation End Products, Advanced; Humans; Logistic Models; Lysine; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Predictive Value of Tests; ROC Curve; Severity of Illness Index; Tunisia; Up-Regulation | 2014 |
Quantitation of Maillard reaction products in commercially available pet foods.
Topics: Animal Feed; Animals; Cats; Consumer Product Safety; Dogs; Food Handling; Furaldehyde; Hot Temperature; Lysine; Lysinoalanine; Maillard Reaction | 2014 |
Increased renal semicarbazide-sensitive amine oxidase activity and methylglyoxal levels in aristolochic acid-induced nephrotoxicity.
Topics: Amine Oxidase (Copper-Containing); Animals; Aristolochic Acids; Dose-Response Relationship, Drug; Kidney; Kidney Diseases; Lysine; Male; Metformin; Mice; Mice, Inbred C57BL; Pyruvaldehyde | 2014 |
Recombinant antibody color resulting from advanced glycation end product modifications.
Topics: Animals; Antibodies, Monoclonal; CHO Cells; Chromatography, Gel; Color; Cricetulus; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Immunoglobulin G; Lysine; Mass Spectrometry; Protein Processing, Post-Translational; Recombinant Proteins | 2014 |
Treatment of proteins with dietary polyphenols lowers the formation of AGEs and AGE-induced toxicity.
Topics: Caseins; Catechin; Cell Proliferation; Cells, Cultured; Chlorogenic Acid; Cinnamates; Depsides; Flavanones; Glucose; Glycation End Products, Advanced; Glycosylation; Hot Temperature; Humans; Lysine; Models, Molecular; Oxidative Stress; Phloretin; Polyphenols; Reactive Oxygen Species; Rosmarinic Acid | 2014 |
Fermented soy permeate reduces cytokine level and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dietary Supplements; Fermentation; Galactose; Glycine max; Inflammation; Interleukins; Isoflavones; Isoprostanes; Lysine; Male; Oligosaccharides; Oxidative Stress; Phytotherapy; Plant Extracts; Rats, Wistar; Superoxide Dismutase; Uric Acid | 2015 |
Carbon nanotube-bilirubin oxidase bioconjugate as a new biofuel cell label for self-powered immunosensor.
Topics: Bioelectric Energy Sources; Enzyme-Linked Immunosorbent Assay; Immunoassay; Lysine; Nanotubes, Carbon; Oxidoreductases Acting on CH-CH Group Donors | 2014 |
Physicochemical analysis of structural alteration and advanced glycation end products generation during glycation of H2A histone by 3-deoxyglucosone.
Topics: Arginine; Chromatography, High Pressure Liquid; Circular Dichroism; Deoxyglucose; Fluorescence; Glycation End Products, Advanced; Glycosylation; Histones; Humans; Lysine; Spectroscopy, Fourier Transform Infrared | 2014 |
Increased peritoneal damage in glyoxalase 1 knock-down mice treated with peritoneal dialysis.
Topics: Animals; Female; Glycation End Products, Advanced; Immunoenzyme Techniques; Inflammation; Lactoylglutathione Lyase; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neovascularization, Pathologic; Peritoneal Dialysis; Peritoneal Fibrosis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2015 |
Natural compounds from grape by-products enhance nutritive value and reduce formation of CML in model muffins.
Topics: Cooking; Food Analysis; Lysine; Nutritive Value; Vitis | 2015 |
Formation of advanced glycation endproducts in ground beef under pasteurisation conditions.
Topics: Animals; Cattle; Chromatography, Liquid; Glycation End Products, Advanced; Hot Temperature; Lysine; Meat; Pasteurization; Tandem Mass Spectrometry | 2015 |
Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of D-galactose treated mice.
Topics: Aging; Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Caspase 3; Dose-Response Relationship, Drug; Down-Regulation; Galactose; Glial Fibrillary Acidic Protein; Glutathione; Glutathione Peroxidase; Glycation End Products, Advanced; Interleukin-6; Lysine; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pentacyclic Triterpenes; Protein Carbonylation; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Up-Regulation | 2015 |
Analysis of inflammatory cells and mediators in skin wound biopsies to determine wound age in living subjects in forensic medicine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers; Biopsy; Female; Forensic Pathology; Granulocyte Colony-Stimulating Factor; Humans; Immunohistochemistry; Interleukin-3; Interleukin-8; Leukocyte Common Antigens; Lysine; Macrophage Inflammatory Proteins; Male; Middle Aged; Recombinant Fusion Proteins; Skin; Time Factors; Vitronectin; Young Adult | 2015 |
Simultaneous analysis of N(ε) -(carboxymethyl)Lysine and N(ε) -(carboxyethyl)lysine in foods by ultra-performance liquid chromatography-mass spectrometry with derivatization by 9-fluorenylmethyl chloroformate.
Topics: Chromatography, Liquid; Fluorenes; Food Analysis; Glycation End Products, Advanced; Humans; Indicators and Reagents; Lysine; Mass Spectrometry; Reproducibility of Results | 2015 |
Betanin reduces the accumulation and cross-links of collagen in high-fructose-fed rat heart through inhibiting non-enzymatic glycation.
Topics: Animals; Betacyanins; Blood Glucose; Collagen; Connective Tissue Growth Factor; Fibrosis; Fructose; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Heart; Insulin; Lysine; Male; Myocardium; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2015 |
Decrease in circulating concentrations of soluble receptors for advanced glycation end products at the time of seroconversion to autoantibody positivity in children with prediabetes.
Topics: Autoantibodies; Case-Control Studies; Child; Child, Preschool; Diabetes Mellitus, Type 1; Disease Progression; Down-Regulation; Female; Humans; Infant; Infant, Newborn; Lysine; Male; Prediabetic State; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2015 |
Increased accumulation of protein-bound N(ε)-(carboxymethyl)lysine in tissues of healthy rats after chronic oral N(ε)-(carboxymethyl)lysine.
Topics: Animals; Kidney; Liver; Lung; Lysine; Male; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Spleen | 2015 |
Formula-derived advanced glycation end products are involved in the development of long-term inflammation and oxidative stress in kidney of IUGR piglets.
Topics: Animals; Cell Nucleus; Fetal Growth Retardation; Glycation End Products, Advanced; Inflammation; Kidney; Lipid Peroxidation; Liver; Lysine; Oxidative Stress; Receptor for Advanced Glycation End Products; Renin-Angiotensin System; Swine | 2015 |
Dietary CML-enriched protein induces functional arterial aging in a RAGE-dependent manner in mice.
Topics: Aging; Animals; Arteries; Dietary Proteins; Endothelium, Vascular; Lysine; Male; Mice; Mice, Inbred C57BL; Pulse Wave Analysis; Receptor for Advanced Glycation End Products; Sirtuin 1; Vascular Cell Adhesion Molecule-1; Vascular Stiffness | 2015 |
The rehabilitation of raw and brown butters by the measurement of two of the major Maillard products, N(ε)-carboxymethyl-lysine and 5-hydroxymethylfurfural, with validated chromatographic methods.
Topics: Butter; Chromatography, Liquid; Cooking; Furaldehyde; Humans; Lysine; Maillard Reaction; Mass Spectrometry | 2015 |
Assessment of the concentrations of various advanced glycation end-products in beverages and foods that are commonly consumed in Japan.
Topics: Antibodies; Atherosclerosis; Beverages; Biomarkers; Enzyme-Linked Immunosorbent Assay; Food Analysis; Glycation End Products, Advanced; Humans; Japan; Lysine; Risk Factors | 2015 |
A DFT study of the carboxymethyl-phosphatidylethanolamine formation from glyoxal and phosphatidylethanolamine surface. Comparison with the formation of N(ε)-(carboxymethyl)lysine from glyoxal and L-lysine.
Topics: Glycation End Products, Advanced; Glyoxal; Hydrogen Bonding; Lysine; Models, Molecular; Phosphatidylethanolamines; Thermodynamics | 2015 |
Dietary L-methionine restriction decreases oxidative stress in porcine liver mitochondria.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Deoxyguanosine; Diet; DNA Damage; Electron Transport; Glutamates; Lysine; Methionine; Mitochondria, Liver; Oxidative Stress; Reactive Oxygen Species; Swine | 2015 |
In vitro glycation of an endothelialized and innervated tissue-engineered skin to screen anti-AGE molecules.
Topics: Animals; Capillaries; Cattle; Cell Differentiation; Cells, Cultured; Collagen; Cytoskeleton; Dermis; Endothelial Cells; Fibroblasts; Filaggrin Proteins; Glycation End Products, Advanced; Glycosylation; Glyoxal; Guanidines; Humans; Keratinocytes; Lysine; Mice; Neurons; Protective Agents; Skin; Thiazoles; Tissue Engineering | 2015 |
Circulating levels of soluble receptor for advanced glycation end products and ligands of the receptor for advanced glycation end products in patients with acute liver failure.
Topics: Acetaminophen; Adult; Biomarkers; Case-Control Studies; Female; Glycation End Products, Advanced; HMGB1 Protein; Humans; Liver Failure, Acute; Lysine; Male; Middle Aged; Prospective Studies; Receptor for Advanced Glycation End Products; S100A12 Protein; Young Adult | 2015 |
Diabetes-induced alterations in tissue collagen and carboxymethyllysine in rat kidneys: Association with increased collagen-degrading proteinases and amelioration by Cu(II)-selective chelation.
Topics: Animals; Chelating Agents; Collagen; Copper; Diabetes Mellitus, Experimental; Kidney; Lysine; Male; Peptide Hydrolases; Protein Processing, Post-Translational; Rats; Rats, Wistar; Streptozocin; Trientine | 2015 |
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with arterial stiffness in older adults.
Topics: Aged; Aging; Aorta; Body Composition; Cardiovascular Diseases; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Hypertension; Inflammation; Linear Models; Lipoproteins, HDL; Logistic Models; Lysine; Male; Odds Ratio; Pulse Wave Analysis; Smoking; Vascular Stiffness | 2015 |
Cardiomyocyte mitochondrial respiration is reduced by receptor for advanced glycation end-product signaling in a ceramide-dependent manner.
Topics: Animals; Cell Respiration; Ceramides; Fatty Acids, Monounsaturated; Glycation End Products, Advanced; Heart Ventricles; In Vitro Techniques; Lysine; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria, Heart; Myocytes, Cardiac; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction; Tobacco Smoke Pollution | 2015 |
Impact of Oxidative Stress Biomarkers and Carboxymethyllysine (an Advanced Glycation End Product) on Prostate Cancer: A Prospective Study.
Topics: Aged; Biomarkers; Case-Control Studies; Humans; Lysine; Male; Middle Aged; Oxidative Stress; Prospective Studies; Prostatic Neoplasms; Regression Analysis | 2015 |
N(ε)-Carboxymethyl Modification of Lysine Residues in Pathogenic Prion Isoforms.
Topics: Animals; Cell Compartmentation; Cell Membrane; Endopeptidase K; Glycation End Products, Advanced; Glycosylation; Lysine; Male; Mesocricetus; Neurons; Protein Isoforms; PrPSc Proteins; Solubility; Thalamus; Tyrosine 3-Monooxygenase | 2016 |
The RAGE receptor and its ligands are highly expressed in astrocytes in a grade-dependant manner in the striatum and subependymal layer in Huntington's disease.
Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Astrocytes; Corpus Striatum; Ependyma; Female; Formins; Humans; Huntington Disease; Lysine; Male; MAP Kinase Signaling System; Microglia; Middle Aged; Nerve Tissue Proteins; Neurons; NF-kappa B; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Calcium Binding Protein beta Subunit; Severity of Illness Index | 2015 |
Development of Diagnostic Fragment Ion Library for Glycated Peptides of Human Serum Albumin: Targeted Quantification in Prediabetic, Diabetic, and Microalbuminuria Plasma by Parallel Reaction Monitoring, SWATH, and MSE.
Topics: Albuminuria; Amino Acid Sequence; Analysis of Variance; Diabetes Mellitus; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Lysine; Molecular Sequence Data; Peptide Library; Peptides; Prediabetic State; Serum Albumin; Tandem Mass Spectrometry | 2015 |
Quantification of Nε-(2-Furoylmethyl)-L-lysine (furosine), Nε-(Carboxymethyl)-L-lysine (CML), Nε-(Carboxyethyl)-L-lysine (CEL) and total lysine through stable isotope dilution assay and tandem mass spectrometry.
Topics: Chromatography, Liquid; Food Analysis; Indicator Dilution Techniques; Isotopes; Lysine; Protein Conformation; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |
LC-MS/MS for the simultaneous determination of polar endogenous ADMA and CML in plasma and urine from diabetics.
Topics: Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Linear Models; Lysine; Retrospective Studies; Tandem Mass Spectrometry | 2015 |
Stability of Individual Maillard Reaction Products in the Presence of the Human Colonic Microbiota.
Topics: Adult; Bacteria; Colon; Female; Gastrointestinal Microbiome; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Norleucine; Pyridones; Pyrroles | 2015 |
Houttuynia cordata aqueous extract attenuated glycative and oxidative stress in heart and kidney of diabetic mice.
Topics: Animals; Arginine; Blood Glucose; Blood Urea Nitrogen; Creatine Kinase; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fructose; Glutathione; Heart; Houttuynia; Insulin; Interleukin-6; Kidney; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Oxidative Stress; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Tumor Necrosis Factor-alpha | 2016 |
Atrial fibrillation coincides with the advanced glycation end product N(ε)-(carboxymethyl)lysine in the atrium.
Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Female; Fibrosis; Granulocytes; Heart Atria; Humans; Lymphocytes; Lysine; Macrophages; Male; Middle Aged; Myocardium; Vascular Cell Adhesion Molecule-1 | 2015 |
The receptor for advanced glycation end products and risk of peripheral arterial disease, amputation or death in type 2 diabetes: a population-based cohort study.
Topics: Aged; Amputation, Surgical; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Progression; Disease-Free Survival; Female; Humans; Incidence; Kaplan-Meier Estimate; Lysine; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Receptor for Advanced Glycation End Products; Risk Assessment; Risk Factors; S100A12 Protein; Sweden; Time Factors | 2015 |
Advanced Glycation End Products Modulate Structure and Drug Binding Properties of Albumin.
Topics: Animals; Binding Sites; Cattle; Circular Dichroism; Glycation End Products, Advanced; Glycosylation; Lysine; Molecular Dynamics Simulation; Ornithine; Protein Binding; Protein Conformation; Pyrimidines; Serum Albumin, Bovine | 2015 |
Kinetics of N(ε)-(carboxymethyl)lysine formation in aqueous model systems of sugars and casein.
Topics: Carbohydrates; Caseins; Kinetics; Lysine; Maillard Reaction; Oxidation-Reduction | 2016 |
Carboxymethyl lysine, an advanced glycation end product, and incident diabetes: a case-cohort analysis of the ARIC Study.
Topics: Atherosclerosis; Case-Control Studies; Cohort Studies; Diabetes Mellitus; Diabetic Angiopathies; Female; Glycation End Products, Advanced; Humans; Incidence; Lysine; Male; Middle Aged; Risk Factors | 2016 |
Nε-(carboxymethyl) lysine-induced mitochondrial fission and mitophagy cause decreased insulin secretion from β-cells.
Topics: Animals; Antioxidants; Biomarkers; Cell Line, Tumor; Diabetes Mellitus; Dietary Supplements; Down-Regulation; Glycation End Products, Advanced; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lysine; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondrial Dynamics; Mitophagy; Oxidants; Phagosomes; Rats; Receptor for Advanced Glycation End Products; Serum Albumin, Bovine; Thioctic Acid | 2015 |
Treadmill Exercise Attenuates Retinal Oxidative Stress in Naturally-Aged Mice: An Immunohistochemical Study.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Deoxyguanosine; Lysine; Male; Mice; Oxidative Stress; Physical Conditioning, Animal; Retina; Tyrosine | 2015 |
Protein-Bound Plasma Nε-(Carboxymethyl)lysine Is Inversely Associated With Central Obesity and Inflammation and Significantly Explain a Part of the Central Obesity-Related Increase in Inflammation: The Hoorn and CODAM Studies.
Topics: Absorptiometry, Photon; Adiposity; Adult; Aged; Biomarkers; Body Mass Index; Chromatography, Liquid; Cross-Sectional Studies; Disease Progression; Female; Humans; Inflammation; Inflammation Mediators; Linear Models; Lysine; Male; Middle Aged; Multivariate Analysis; Netherlands; Obesity, Abdominal; Obesity, Morbid; Prospective Studies; Risk Factors; Tandem Mass Spectrometry; Waist Circumference | 2015 |
Impact of Variety and Agronomic Factors on Crude Protein and Total Lysine in Chicory; N(ε)-Carboxymethyl-lysine-Forming Potential during Drying and Roasting.
Topics: Cichorium intybus; Coffee; Food Handling; Lysine; Maillard Reaction; Plant Proteins; Plant Roots | 2015 |
Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus.
Topics: Animals; Cell Movement; Cells, Cultured; Diabetes Complications; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Glycation End Products, Advanced; Homeodomain Proteins; Humans; Kidney; Lysine; NF-kappa B; Podocytes; Proteinuria; Rats; Rats, Wistar; Repressor Proteins; Zinc Finger E-box Binding Homeobox 2 | 2016 |
Ameliorating Effect of Akebia quinata Fruit Extracts on Skin Aging Induced by Advanced Glycation End Products.
Topics: Adult; Antioxidants; Cell Line; Female; Fibrillin-1; Fibrillins; Fibroblasts; Fruit; Glycation End Products, Advanced; Humans; Lysine; Magnoliopsida; Microfilament Proteins; Middle Aged; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Skin; Skin Aging | 2015 |
Influence of home cooking conditions on Maillard reaction products in beef.
Topics: Acrylamide; Color; Cooking; Diet, Diabetic; Hot Temperature; Humans; Lysine; Maillard Reaction; Red Meat | 2016 |
Serum carboxymethyl-lysine, a dominant advanced glycation end product, is increased in women with gestational diabetes mellitus.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes, Gestational; Early Diagnosis; Female; Glucose Intolerance; Humans; Lysine; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Second | 2016 |
Effects of Long-Term Exposure to Free Nε-(Carboxymethyl)lysine on Rats Fed a High-Fat Diet.
Topics: Animals; Blood Glucose; Diet, High-Fat; Energy Metabolism; Glycation End Products, Advanced; Lipoproteins, LDL; Lysine; Male; Protein Binding; Rats; Rats, Sprague-Dawley; Risk Factors | 2015 |
iRAGE as a novel carboxymethylated peptide that prevents advanced glycation end product-induced apoptosis and endoplasmic reticulum stress in vascular smooth muscle cells.
Topics: Animals; Apoptosis; Caspase 3; Caspase 7; Cell Line; Endoplasmic Reticulum Stress; Glycation End Products, Advanced; Lysine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Peptides; Proto-Oncogene Proteins c-bcl-2; Rats; Receptor for Advanced Glycation End Products; Serum Albumin | 2016 |
Two new prenylflavonoids from Epimedii Herba and their inhibitory effects on advanced glycation end-products.
Topics: Animals; Arginine; Diabetes Complications; Drugs, Chinese Herbal; Epimedium; Flavonoids; Glycation End Products, Advanced; Lysine; Male; Phytotherapy; Plant Components, Aerial; Prenylation; Rats | 2016 |
Association of serum N(ε)-Carboxy methyl lysine with severity of diabetic retinopathy.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Humans; Lysine; Male; Middle Aged; Severity of Illness Index | 2016 |
Short-term effects of dietary advanced glycation end products in rats.
Topics: Animals; Biomarkers; Diet; Energy Intake; Glycation End Products, Advanced; Hexosyltransferases; Hot Temperature; Imidazoles; Imidazolines; Lysine; Male; Milk Proteins; Molecular Weight; Proteolysis; Random Allocation; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Renal Elimination; Toxicity Tests, Subacute; Tumor Necrosis Factor-alpha; Up-Regulation | 2016 |
Formation of free and protein-bound carboxymethyllysine and carboxyethyllysine in meats during commercial sterilization.
Topics: Animals; Cattle; Chickens; Food Analysis; Food Preservation; Lysine; Meat; Sterilization; Swine | 2016 |
Prevention of age-induced N(ε)-(carboxymethyl)lysine accumulation in the microvasculature.
Topics: Aging; Animals; Apolipoproteins E; Brain; Coronary Vessels; Endothelium, Vascular; Lysine; Mice, Inbred Strains; Microvessels; Superoxide Dismutase; Survival Rate | 2016 |
Advanced Glycation End Products Evolution after Pancreas-Kidney Transplantation: Plasmatic and Cutaneous Assessments.
Topics: Adult; Biopsy; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Immunosuppression Therapy; Kidney Transplantation; Lysine; Male; Middle Aged; Oxygen; Pancreas Transplantation; Prospective Studies; Proteins; Skin; Time Factors | 2016 |
Nε-(carboxymethyl)-lysine, White Matter, and Cognitive Function in Diabetes Patients.
Topics: Aged; Anisotropy; Case-Control Studies; Cognition Disorders; Diabetes Mellitus, Type 2; Diffusion Magnetic Resonance Imaging; Female; Humans; Image Processing, Computer-Assisted; Leukoencephalopathies; Lysine; Male; Mental Status Schedule; Neuropsychological Tests | 2016 |
The Receptor for Advanced Glycation End Products (Rage) and Its Ligands in Plasma and Infrainguinal Bypass Vein.
Topics: Adult; Aged; Amputation, Surgical; Biomarkers; Diabetic Angiopathies; Disease-Free Survival; Female; Glycation End Products, Advanced; Humans; Kaplan-Meier Estimate; Ligands; Lysine; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Prospective Studies; Receptor for Advanced Glycation End Products; Reoperation; Risk Factors; S100A12 Protein; Time Factors; Treatment Outcome; Up-Regulation; Vascular Grafting; Veins | 2016 |
The glyoxalase enzymes are differentially localized in epidermis and regulated during ageing and photoageing.
Topics: Adult; Aged; Epidermis; Humans; Lactoylglutathione Lyase; Lysine; Middle Aged; Skin; Skin Aging; Thiolester Hydrolases | 2016 |
Toxicological evaluation of advanced glycation end product Nε-(carboxymethyl)lysine: Acute and subacute oral toxicity studies.
Topics: Administration, Oral; Animals; Biomarkers; Dose-Response Relationship, Drug; Eating; Female; Food Contamination; Food Handling; Kidney; Lethal Dose 50; Lipid Peroxidation; Liver; Lysine; Mice; Organ Size; Oxidative Stress; Risk Assessment; Toxicity Tests, Acute; Toxicity Tests, Subacute; Weight Loss | 2016 |
Bioactive compounds isolated from apple, tea, and ginger protect against dicarbonyl induced stress in cultured human retinal epithelial cells.
Topics: Catechin; Catechols; Cell Line; Epithelial Cells; Fatty Alcohols; Glutathione; Glycation End Products, Advanced; Heme Oxygenase-1; Humans; Lysine; Malus; NF-E2-Related Factor 2; Phloretin; Phytochemicals; Protective Agents; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Retinal Pigment Epithelium; Tea; Zingiber officinale | 2016 |
The impact of raw materials and baking conditions on Maillard reaction products, thiamine, folate, phytic acid and minerals in white bread.
Topics: Bread; Cooking; Dietary Proteins; Flour; Folic Acid; Food Analysis; Food Handling; Furaldehyde; Lysine; Maillard Reaction; Phytic Acid; Thiamine; Trace Elements; Triticum | 2016 |
ADMA: a specific biomarker for pathologic progress in diabetic microvascular complications?
Topics: Adult; Aged; Area Under Curve; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Logistic Models; Lysine; Male; Middle Aged; Odds Ratio; Prediabetic State; ROC Curve; Tandem Mass Spectrometry | 2016 |
Update on Mechanisms of Renal Tubule Injury Caused by Advanced Glycation End Products.
Topics: ATP Binding Cassette Transporter 1; Cell Line; Cholesterol; Diabetic Nephropathies; Endoplasmic Reticulum Stress; Epithelial Cells; Foam Cells; Glycation End Products, Advanced; Humans; Kidney Tubules; Lipid Metabolism; Liver X Receptors; Lysine; Receptors, LDL; Sterol Regulatory Element Binding Protein 2 | 2016 |
Increased levels of N(ε)- Carboxy methyl lysine (N(ε)-CML) are associated with topographic alterations in retinal pigment epithelium: A preliminary study.
Topics: Adult; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Female; Glycated Hemoglobin; Humans; Lysine; Male; Middle Aged; Prospective Studies; Regression Analysis; Retinal Pigment Epithelium; Severity of Illness Index; Tertiary Care Centers; Up-Regulation; Vitreoretinopathy, Proliferative | 2016 |
Eucommia ulmoides extracts prevent the formation of advanced glycation end products.
Topics: Arginine; Eucommiaceae; Flavonoids; Fructose; Galactose; Gelatin; Glucose; Glycation End Products, Advanced; Glycosides; Lysine; Mannose; Plant Extracts; Ribose; Tandem Mass Spectrometry | 2016 |
Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dinoprost; Embryo, Mammalian; Embryonic Development; Female; Fetal Development; Fetal Resorption; Gene Expression; Liver; Lysine; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Pregnancy; Pregnancy in Diabetics; Pyruvaldehyde; Receptor for Advanced Glycation End Products | 2016 |
N(ϵ) -Carboxymethyllysine Increases the Expression of miR-103/143 and Enhances Lipid Accumulation in 3T3-L1 Cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Apoptosis; Blotting, Western; Cell Proliferation; Fatty Acids; Glucose; Humans; Lipid Metabolism; Lysine; Mice; MicroRNAs; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2016 |
N-carboxymethyllysine as a biomarker for coronary artery disease and age-related macular degeneration.
Topics: Aged; Aging; Biomarkers; Body Mass Index; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Early Diagnosis; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lipoproteins; Lysine; Macular Degeneration; Male; Middle Aged; Oxidative Stress; Prevalence; Risk Factors | 2016 |
Serum advanced glycation endproducts are associated with left ventricular dysfunction in normal glucose metabolism but not in type 2 diabetes: The Hoorn Study.
Topics: Aged; Arginine; Biomarkers; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Echocardiography; Female; Glycation End Products, Advanced; Humans; Linear Models; Lysine; Male; Middle Aged; Myocardial Contraction; Netherlands; Predictive Value of Tests; Prognosis; Risk Assessment; Risk Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2016 |
A Retrospective Study in Adults with Metabolic Syndrome: Diabetic Risk Factor Response to Daily Consumption of Agaricus bisporus (White Button Mushrooms).
Topics: Adiponectin; Adult; Agaricus; Antioxidants; beta-Glucans; Biomarkers; Body Mass Index; Chitin; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet; Dinoprost; Ergothioneine; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Insulin Resistance; Leptin; Linear Models; Lysine; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Oxidative Stress; Polyphenols; Pyruvaldehyde; Retrospective Studies; Risk Factors; Triglycerides; Vitamin D | 2016 |
Application of Quantum Dot-Molecularly Imprinted Polymer Core-Shell Particles Sensitized with Graphene for Optosensing of N(ε)-Carboxymethyllysine in Dairy Products.
Topics: Dairy Products; Food Analysis; Graphite; Hydrophobic and Hydrophilic Interactions; Infant Formula; Lysine; Molecular Imprinting; Nanoparticles; Optics and Photonics; Quantum Dots; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2016 |
Encapsulation of ascorbic acid promotes the reduction of Maillard reaction products in UHT milk.
Topics: Animals; Ascorbic Acid; Food Handling; Food, Fortified; Glycation End Products, Advanced; Lysine; Maillard Reaction; Mass Spectrometry; Milk | 2016 |
Isoferulic Acid Action against Glycation-Induced Changes in Structural and Functional Attributes of Human High-Density Lipoprotein.
Topics: Aldehydes; Aryldialkylphosphatase; Cimicifuga; Cinnamates; Glycation End Products, Advanced; Glycosylation; Humans; Lipoproteins, HDL; Lysine; Protective Agents; Spectrometry, Fluorescence; Transition Temperature; Tryptophan | 2016 |
Determination of advanced glycation end-products and antibodies against them (anti-CML and anti-CEL) in the serum of Graves' orbitopathy patients before and after methylprednisolone treatment.
Topics: Adult; Anti-Inflammatory Agents; Autoantibodies; Female; Glycation End Products, Advanced; Graves Ophthalmopathy; Humans; Lysine; Male; Methylprednisolone; Middle Aged | 2016 |
Quantitative assessment of organ distribution of dietary protein-bound
Topics: Animals; Diet; Dietary Proteins; Glycation End Products, Advanced; Humans; Kidney; Liver; Lysine; Mice | 2016 |
The effects of n-3 long-chain polyunsaturated fatty acid supplementation on AGEs and sRAGE in type 2 diabetes mellitus.
Topics: Aged; Animals; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Dietary Supplements; Fasting; Fatty Acids, Omega-3; Female; Gene Expression Regulation; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Lysine; Male; Middle Aged; NF-kappa B; Receptor for Advanced Glycation End Products; Signal Transduction; Waist Circumference | 2016 |
Antiglycation and Antioxidant Properties of Momordica charantia.
Topics: Antioxidants; Chelating Agents; Enzyme-Linked Immunosorbent Assay; Flavonoids; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Lysine; Momordica charantia; Oxidative Stress; Phenols; Plant Extracts | 2016 |
Advanced Glycation End-Products Enhance Lung Cancer Cell Invasion and Migration.
Topics: Arginine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Fibronectins; Glycation End Products, Advanced; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Lung Neoplasms; Lysine; Matrix Metalloproteinase 2; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2016 |
Simultaneous Quantitation of Advanced Glycation End Products in Soy Sauce and Beer by Liquid Chromatography-Tandem Mass Spectrometry without Ion-Pair Reagents and Derivatization.
Topics: Arginine; Beer; Chromatography, Liquid; Food Analysis; Glycation End Products, Advanced; Heating; Imidazoles; Lysine; Ornithine; Reproducibility of Results; Sensitivity and Specificity; Soy Foods; Tandem Mass Spectrometry | 2016 |
Plasma Levels of Pentosidine, Carboxymethyl-Lysine, Soluble Receptor for Advanced Glycation End Products, and Metabolic Syndrome: The Metformin Effect.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Lysine; Male; Metabolic Syndrome; Metformin; Middle Aged; Prognosis; Receptor for Advanced Glycation End Products | 2016 |
The receptor for advanced glycation end products impairs collateral formation in both diabetic and non-diabetic mice.
Topics: Animals; Blood Glucose; Collateral Circulation; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycation End Products, Advanced; Hindlimb; HMGB1 Protein; Immunoblotting; Immunohistochemistry; Ischemia; Lipids; Lysine; Male; Mice, Inbred C57BL; Mice, Knockout; Receptor for Advanced Glycation End Products | 2017 |
Inhibitory effect of sugarcane molasses extract on the formation of N
Topics: Antioxidants; Glucose; Glycation End Products, Advanced; Lysine; Maillard Reaction; Molasses; Pyruvaldehyde; Saccharum | 2017 |
Accumulation of the advanced glycation end product carboxymethyl lysine in breast cancer is positively associated with estrogen receptor expression and unfavorable prognosis in estrogen receptor-negative cases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Female; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Prognosis; Receptors, Estrogen; Survival Analysis; Tumor Cells, Cultured; Young Adult | 2017 |
Potential involvement of dietary advanced glycation end products in impairment of skeletal muscle growth and muscle contractile function in mice.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Gene Expression Regulation; Glycation End Products, Advanced; Lysine; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Skeletal; Myogenic Regulatory Factors; RNA, Messenger | 2017 |
Immunoglobulin-G Glycation by Fructose Leads to Structural Perturbations and Drop Off in Free Lysine and Arginine Residues.
Topics: Arginine; Fructose; Glycation End Products, Advanced; Glycosylation; Humans; Immunoglobulin G; Lysine; Monosaccharides; Nitroblue Tetrazolium; Solutions; Spectrometry, Fluorescence | 2017 |
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Triglycerides | 2017 |
Protective role of soluble receptor for advanced glycation end-products in patients with non-alcoholic fatty liver disease.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Humans; Israel; Life Style; Logistic Models; Lysine; Male; Middle Aged; Multivariate Analysis; Non-alcoholic Fatty Liver Disease; Receptor for Advanced Glycation End Products; Solubility; Surveys and Questionnaires | 2017 |
Neuroprotective Effects of a Novel Antioxidant Mixture Twendee X in Mouse Stroke Model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Brain; Deoxyguanosine; Disease Models, Animal; Glycation End Products, Advanced; Infarction, Middle Cerebral Artery; Inflammation Mediators; Lysine; Male; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Time Factors | 2017 |
Evaluation of an olive leaf extract as a natural source of antiglycative compounds.
Topics: Chromatography, Liquid; Deoxyglucose; Fructosamine; Galactose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Olea; Ornithine; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrimidines; Pyruvaldehyde; Tandem Mass Spectrometry | 2017 |
N
Topics: Aged; Aged, 80 and over; Biomarkers; Carotid Arteries; Carotid Stenosis; Chi-Square Distribution; Chromatography, Liquid; Diffusion Magnetic Resonance Imaging; Embolic Protection Devices; Endovascular Procedures; Enzyme-Linked Immunosorbent Assay; Female; Humans; Linear Models; Lysine; Magnetic Resonance Angiography; Male; Molecular Imaging; Multivariate Analysis; Peroxidase; Plaque, Atherosclerotic; Predictive Value of Tests; Registries; Risk Assessment; Risk Factors; Stents; Tandem Mass Spectrometry; Treatment Outcome | 2017 |
Racial differences in circulating levels of the soluble receptor for advanced glycation endproducts in middle-aged and older adults.
Topics: Aged; Aged, 80 and over; Black People; C-Reactive Protein; Female; Heart Rate; Humans; Lysine; Male; Middle Aged; Racial Groups; Receptor for Advanced Glycation End Products; Sex Factors; White People | 2017 |
The receptor for advanced glycation endproducts mediates podocyte heparanase expression through NF-κB signaling pathway.
Topics: Animals; Base Sequence; Cattle; Diabetic Nephropathies; Glucuronidase; Glycation End Products, Advanced; HMGB1 Protein; Kidney Cortex; Lysine; Mice, Inbred C57BL; NF-kappa B; Phosphorylation; Podocytes; Promoter Regions, Genetic; Protein Binding; Proteinuria; Receptor for Advanced Glycation End Products; S100 Proteins; Serum Albumin, Bovine; Signal Transduction; Transcription Factor RelA; Up-Regulation | 2018 |
Fecal excretion of Maillard reaction products and the gut microbiota composition of rats fed with bread crust or bread crumb.
Topics: Animals; Bacteria; Bread; Feces; Gastrointestinal Microbiome; Lysine; Maillard Reaction; Male; Polymers; Rats; Rats, Sprague-Dawley; Triticum | 2017 |
Increased serum concentrations of N
Topics: Adult; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lysine; Male; Middle Aged; Severity of Illness Index | 2018 |
DAF in diabetic patients is subject to glycation/inactivation at its active site residues.
Topics: Amino Acids; Arginine; Catalytic Domain; CD55 Antigens; Complement Activation; Diabetes Mellitus; Erythrocytes; Glucose; Glycation End Products, Advanced; Humans; Lymphocyte Activation; Lysine; Models, Molecular; Ornithine; Protein Conformation; Pyrimidines; Ribose | 2018 |
Hyperglycemia-related advanced glycation end-products is associated with the altered phosphatidylcholine metabolism in osteoarthritis patients with diabetes.
Topics: Aged; Biomarkers; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Hyperglycemia; Lysine; Male; Middle Aged; Osteoarthritis; Phosphatidylcholines; Synovial Fluid; Tandem Mass Spectrometry | 2017 |
Perspective: The Paradox in Dietary Advanced Glycation End Products Research-The Source of the Serum and Urinary Advanced Glycation End Products Is the Intestines, Not the Food.
Topics: Diet; Fruit; Fruit and Vegetable Juices; Glycation End Products, Advanced; High Fructose Corn Syrup; Humans; Intestinal Mucosa; Lysine; Nutritive Sweeteners; Nuts; Observational Studies as Topic; Vegetables | 2017 |
The advanced glycation end product N
Topics: Caco-2 Cells; Glycation End Products, Advanced; Glyoxal; Humans; Lysine; Serotonin | 2018 |
Kinetic investigation of the trapping of Nε-(carboxymethyl)lysine by 4-methylbenzoquinone: A new mechanism to control Nε-(carboxymethyl)lysine levels in foods.
Topics: Benzoquinones; Chromatography, Liquid; Food; Glycation End Products, Advanced; Hydrogen-Ion Concentration; Kinetics; Lysine; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry | 2018 |
CML/CD36 accelerates atherosclerotic progression via inhibiting foam cell migration.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; CD36 Antigens; Cell Migration Inhibition; Cell Movement; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Foam Cells; Glycation End Products, Advanced; Lysine; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; RAW 264.7 Cells | 2018 |
Comparative evaluation of three different ELISA assays and HPLC-ESI-ITMS/MS for the analysis of N
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Fishes; Food Contamination; Fruit; Glycation End Products, Advanced; Lysine; Mass Spectrometry; Meat; Swine; Vegetables | 2018 |
Effects of Weight Loss on Advanced Glycation End Products in Subjects with and without Diabetes: A Preliminary Report.
Topics: Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Overweight; Prediabetic State; Weight Loss | 2017 |
The quantification of free Amadori compounds and amino acids allows to model the bound Maillard reaction products formation in soybean products.
Topics: Amino Acids; Discriminant Analysis; Food Analysis; Food Handling; Glycation End Products, Advanced; Glycine max; Lysine; Maillard Reaction; Mass Spectrometry; Plant Proteins | 2018 |
Dietary intake of advanced glycation endproducts is associated with higher levels of advanced glycation endproducts in plasma and urine: The CODAM study.
Topics: Aged; Atherosclerosis; Body Mass Index; Cohort Studies; Diabetes Mellitus; Diet; Female; Food Handling; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Ornithine; Waist Circumference | 2018 |
Effect of different cooking conditions on the profiles of Maillard reaction products and nutrient composition of hairtail (Thichiurus lepturus) fillets.
Topics: Animals; Cooking; Fishes; Food Handling; Glycation End Products, Advanced; Hot Temperature; Lipids; Lysine; Maillard Reaction; Nutritive Value; Seafood; Thiobarbituric Acid Reactive Substances; Water | 2018 |
Accumulation of carboxymethyl-lysine (CML) in human cortical bone.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Bone and Bones; Cell Survival; Collagen; Cortical Bone; Female; Fractures, Bone; Glycation End Products, Advanced; Humans; Hydroxyproline; Linear Models; Lysine; Male; Mass Spectrometry; Middle Aged; Risk; Young Adult | 2018 |
Effects of Highland Barley Bran Extract Rich in Phenolic Acids on the Formation of N
Topics: Bread; Cooking; Glycation End Products, Advanced; Hordeum; Hot Temperature; Hydroxybenzoates; Lysine; Maillard Reaction; Models, Chemical; Plant Extracts | 2018 |
A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer.
Topics: Animals; Antibodies, Monoclonal; Atherosclerosis; Epitope Mapping; Female; Glycation End Products, Advanced; Humans; Lysine; Mice; Mice, Inbred BALB C; Pancreatic Neoplasms; Protein Array Analysis | 2018 |
AGE-RAGE Interaction Does Not Explain the Clinical Improvements after Therapeutic Fasting in Osteoarthritis.
Topics: Aged; Fasting; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Osteoarthritis; Quality of Life; Receptor for Advanced Glycation End Products; Treatment Outcome | 2018 |
Novel α-Oxoamide Advanced-Glycation Endproducts within the N
Topics: Animals; Cooking; Glycation End Products, Advanced; Hot Temperature; Liver; Liver Cirrhosis; Lysine; Maillard Reaction; Male; Pyridines; Rats; Rats, Wistar | 2018 |
Advanced glycation endproducts, dityrosine and arginine transporter dysfunction in autism - a source of biomarkers for clinical diagnosis.
Topics: Amino Acid Transport Systems, Basic; Arginine; Autistic Disorder; Biomarkers; Child; Female; Glycation End Products, Advanced; Humans; Lysine; Machine Learning; Male; Oxidative Stress; Sensitivity and Specificity; Tyrosine | 2018 |
The advanced glycation end-product N
Topics: Animals; Antineoplastic Agents; Carcinoma in Situ; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Diabetes Complications; Disease Models, Animal; Disease Progression; Genes, ras; Humans; Lysine; Mice, Inbred C57BL; Mice, Transgenic; Pancreatic Neoplasms; Peptides; Receptor for Advanced Glycation End Products; Risk Factors; Signal Transduction; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Inhibition of Methylglyoxal-Induced Histone H1 N
Topics: Catechin; Glycation End Products, Advanced; Histones; Hydrogen Peroxide; Lysine; Pyruvaldehyde; Schiff Bases | 2018 |
Changes in circulating levels of carboxymethyllysine, soluble receptor for advanced glycation end products (sRAGE), and inflammation markers in women during normal pregnancy.
Topics: Adolescent; Adult; Biomarkers; C-Reactive Protein; Female; Humans; Infant, Newborn; Insulin; Longitudinal Studies; Lysine; Malondialdehyde; Pregnancy; Receptor for Advanced Glycation End Products; Tumor Necrosis Factor-alpha; Young Adult | 2019 |
Investigating the Glycating Effects of Glucose, Glyoxal and Methylglyoxal on Human Sperm.
Topics: DNA Damage; Fertility; Glucose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Male; Pyruvaldehyde; Semen Analysis; Sperm Count; Sperm Motility; Spermatozoa | 2018 |
Prediction of CML contents in the Maillard reaction products for casein-monosaccharides model.
Topics: Caseins; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Lysine; Maillard Reaction; Microscopy, Electron, Transmission; Monosaccharides; Reactive Oxygen Species; Temperature | 2018 |
Impact of free N
Topics: Caco-2 Cells; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Lysine; Maillard Reaction; Receptors, Serotonin; Serotonin; Serum Albumin, Bovine | 2018 |
Investigation of hallmarks of carbonyl stress and formation of end products in feline chronic kidney disease as markers of uraemic toxins.
Topics: Advanced Oxidation Protein Products; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biomarkers; Cats; Lysine; Oxidative Stress; Renal Insufficiency, Chronic; Urea | 2019 |
Advanced glycation end products, protein crosslinks and post translational modifications in pork subjected to different heat treatments.
Topics: Alanine; Animals; Cooking; Dietary Proteins; Glycation End Products, Advanced; Hot Temperature; Humans; Lysine; Maillard Reaction; Muscle Proteins; Nutritive Value; Peptides; Protein Processing, Post-Translational; Protein Stability; Red Meat; Sulfides; Swine; Taste | 2018 |
The in vivo and in vitro approaches for establishing a link between advanced glycation end products and lung cancer.
Topics: A549 Cells; Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Humans; Lung Neoplasms; Lysine; Male; Mice; Protein Carbonylation; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor for Advanced Glycation End Products | 2018 |
Sympathoadrenergic suppression improves heart function by upregulating the ratio of sRAGE/RAGE in hypertension with metabolic syndrome.
Topics: ADAM10 Protein; Analysis of Variance; Animals; Denervation; Disease Models, Animal; Fibroblasts; HMGB1 Protein; Hypertension; Kidney; Leukocytes, Mononuclear; Ligands; Lysine; Male; Metabolic Syndrome; Myocardium; Obesity; Protein Isoforms; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Adrenergic, beta; Statistics, Nonparametric; Sympathetic Nervous System; Up-Regulation | 2018 |
Advanced Glycation End Products and esRAGE Are Associated With Bone Turnover and Incidence of Hip Fracture in Older Men.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Bone Density; Bone Remodeling; Diabetes Mellitus; Follow-Up Studies; Glycation End Products, Advanced; Hip Fractures; Humans; Incidence; Lysine; Male; Predictive Value of Tests; Prognosis; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Risk Factors | 2018 |
N
Topics: Animals; Caseins; Cattle; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Goats; Humans; Hydrolysis; Infant; Infant Formula; Lysine; Whey; Whey Proteins | 2019 |
Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles.
Topics: Animals; Antigens, Neoplasm; Copper Radioisotopes; Glycation End Products, Advanced; Human Umbilical Vein Endothelial Cells; Humans; Lysine; Mice; Mitogen-Activated Protein Kinases; Molecular Imaging; Multimodal Imaging; Nanoparticles; Serum Albumin, Human | 2018 |
Bioactivity of selected materials for coffee substitute.
Topics: Acrylamide; Antioxidants; Beverages; Carbolines; Cichorium intybus; Cynara scolymus; Furans; Harmine; Lysine; Phytochemicals | 2018 |
Dietary Advanced Glycation Endproducts Induce an Inflammatory Response in Human Macrophages in Vitro.
Topics: Antibodies; Caseins; Diet, Western; Endotoxins; Food Contamination; Glycation End Products, Advanced; Glycosylation; Hot Temperature; Humans; Inflammation; Lysine; Macrophages; Maillard Reaction; Receptor for Advanced Glycation End Products; Tumor Necrosis Factor-alpha | 2018 |
Simultaneous Determination of N
Topics: Animals; Chromatography, Liquid; Freeze Drying; Glycation End Products, Advanced; Humans; Lysine; Tandem Mass Spectrometry | 2018 |
Effects of Catechins on N
Topics: Camellia sinensis; Catechin; Food Handling; Lysine; Models, Chemical; Molecular Structure; Plant Leaves; Pyruvaldehyde; Tea | 2019 |
Alpha-lipoic acid suppresses N
Topics: Cells, Cultured; Epithelial-Mesenchymal Transition; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Tubules, Proximal; Lysine; Reactive Oxygen Species; Thioctic Acid | 2018 |
Metabolization of the Advanced Glycation End Product N-ε-Carboxymethyllysine (CML) by Different Probiotic E. coli Strains.
Topics: Chromatography, High Pressure Liquid; Dipeptides; Escherichia coli; Glycation End Products, Advanced; Humans; Lysine; Oxygen; Phenotype; Probiotics; Species Specificity; Tandem Mass Spectrometry | 2019 |
[Preventive Effects of Aphanothece sacrum on Diabetic Cataracts].
Topics: Animals; Cataract; Cyanobacteria; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glycation End Products, Advanced; Lens, Crystalline; Lysine; Male; Mice, Inbred Strains; Oxidative Stress; Streptozocin; Tandem Mass Spectrometry | 2019 |
High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry.
Topics: Analytic Sample Preparation Methods; Biomarkers; Blood Chemical Analysis; Calibration; Humans; Limit of Detection; Lysine; Mass Spectrometry | 2019 |
Skin Autofluorescence Measurement in Subclinical Atheromatous Disease: Results from the ILERVAS Project.
Topics: Arginine; Case-Control Studies; Cross-Sectional Studies; Female; Fluorescence; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Optical Imaging; Plaque, Atherosclerotic; Prognosis; Prospective Studies; ROC Curve; Skin | 2019 |
Exploring the role of body mass index in relationship of serum nitric oxide and advanced glycation end products in apparently healthy subjects.
Topics: Adult; Arginine; Body Mass Index; Cross-Sectional Studies; Female; Glycation End Products, Advanced; Healthy Volunteers; Humans; Lysine; Male; Middle Aged; Nitric Oxide; Young Adult | 2019 |
In vitro formation of Maillard reaction products during simulated digestion of meal-resembling systems.
Topics: Amino Acids; Arginine; Biological Availability; Carbohydrates; Digestion; Fructosamine; Fructose; Glucose; Intestines; Lysine; Maillard Reaction; Malabsorption Syndromes; Meals; Proteins; Starch; Sugars | 2019 |
Structural modification and digestibility change of β-lactoglobulin modified by methylglyoxal with the simulated reheating of dairy products.
Topics: Chromatography, High Pressure Liquid; Dairy Products; Electrophoresis, Polyacrylamide Gel; Lactoglobulins; Lysine; Pepsin A; Pyruvaldehyde; Tandem Mass Spectrometry; Temperature | 2019 |
Metabolic and renal effects of dietary advanced glycation end products in pregnant rats - a pilot study.
Topics: Animals; Diabetes, Gestational; Diet; Female; Glycation End Products, Advanced; Kidney; Lysine; Pilot Projects; Pregnancy; Rats; Rats, Wistar | 2019 |
Studies on mechanism of free Nε-(carboxymethyl)lysine-induced toxic injury in mice.
Topics: Animals; Female; Inflammation; Kidney; Liver; Lysine; Male; Mice; Oxidative Stress; Receptor for Advanced Glycation End Products; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2019 |
Biocatalytic Reversal of Advanced Glycation End Product Modification.
Topics: Biocatalysis; Escherichia coli; Escherichia coli Proteins; Glycation End Products, Advanced; Kinetics; Lysine; Multienzyme Complexes; Mutation; Protein Engineering; Substrate Specificity | 2019 |
Anti-Diabetic Effects of Gynura Bicolor Aqueous Extract in Mice.
Topics: Animals; Antidiuretic Agents; Arginine; Asteraceae; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione; Humans; Kidney; Liver; Lysine; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Plant Extracts; Reactive Oxygen Species | 2019 |
Advanced glycation end product carboxymethyl-lysine and risk of incident peripheral artery disease in older adults: The Cardiovascular Health Study.
Topics: Aged; Biomarkers; Female; Glycation End Products, Advanced; Humans; Incidence; Lysine; Male; Peripheral Arterial Disease; Prognosis; Risk Assessment; Risk Factors; Time Factors; United States | 2019 |
Anaerobic Degradation of N-ε-Carboxymethyllysine, a Major Glycation End-Product, by Human Intestinal Bacteria.
Topics: Adult; Anaerobiosis; Bacteria; Colon; Feces; Gastrointestinal Microbiome; Glycation End Products, Advanced; Glycosylation; Humans; Infant; Lysine | 2019 |
Formation of N
Topics: Camellia sinensis; Catechin; Food Analysis; Food Handling; Gallic Acid; Glyoxal; Lysine; Plant Leaves; Polyphenols; Pyruvaldehyde; Tea | 2019 |
Circulating and Extracellular Vesicles Levels of N-(1-Carboxymethyl)-L-Lysine (CML) Differentiate Early to Moderate Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Biomarkers; Cell Line; Diagnosis, Differential; Disease Progression; Extracellular Vesicles; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Mental Status and Dementia Tests; Neurons | 2019 |
Differential Effects of Dry vs. Wet Heating of β-Lactoglobulin on Formation of sRAGE Binding Ligands and sIgE Epitope Recognition.
Topics: Epitopes; Glycation End Products, Advanced; Hot Temperature; Immunoglobulin E; Lactoglobulins; Lactose; Ligands; Lysine; Milk Hypersensitivity; Protein Aggregates; Protein Binding; Protein Conformation; Receptor for Advanced Glycation End Products; Water | 2019 |
Physico-chemical Changes Induced in the Serum Proteins Immunoglobulin G and Fibrinogen Mediated by Methylglyoxal.
Topics: Arginine; Benzothiazoles; Fibrinogen; Furaldehyde; Glycation End Products, Advanced; Glycosylation; Humans; Immunoglobulin G; Kinetics; Lysine; Malondialdehyde; Oxidation-Reduction; Protein Carbonylation; Pyruvaldehyde; Solutions; Spectrometry, Fluorescence | 2020 |
Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes.
Topics: Aged; Case-Control Studies; Cell Death; Cell Line; Dyslipidemias; Female; Gene Expression Profiling; Gene Ontology; Glycated Serum Albumin; Glycation End Products, Advanced; Glycosylation; Heart Failure; HSP90 Heat-Shock Proteins; Humans; Hypertension; Interleukin-6; Lysine; Male; Middle Aged; Molecular Sequence Annotation; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Protein Carbonylation; Protein Processing, Post-Translational; Reactive Oxygen Species; Serum Albumin; Serum Albumin, Human; Tumor Necrosis Factor-alpha | 2019 |
Early and advanced stages of Maillard reaction in infant formulas: Analysis of available lysine and carboxymethyl-lysine.
Topics: Commerce; Food Analysis; Food Contamination; Food Storage; Humans; Infant; Infant Formula; Lysine; Maillard Reaction; Powders; Time Factors | 2019 |
Relationship among urinary advanced glycation-end products, skeletal muscle mass and physical performance in community-dwelling older adults.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Creatinine; Cross-Sectional Studies; Female; Geriatric Assessment; Glycation End Products, Advanced; Hand Strength; Humans; Independent Living; Lysine; Male; Muscle Strength; Muscle, Skeletal; Physical Functional Performance; Sarcopenia; Time and Motion Studies; Urea | 2019 |
Topics: Animals; Arginine; Collagen Type I; Glycation End Products, Advanced; Glycosylation; Lysine; Mice | 2019 |
Effect of N(Epsilon)-(carboxymethyl)lysine on Laboratory Parameters and Its Association with
Topics: Anemia, Sickle Cell; Antisickling Agents; Aspartate Aminotransferases; beta-Globins; Child; Creatinine; Female; Genotype; Haplotypes; Humans; Hydroxyurea; Inflammation; L-Lactate Dehydrogenase; Leukocytes; Lysine; Male | 2019 |
Study of reactions of Nε-(carboxymethyl) lysine with o-benzoquinones by cyclic voltammetry.
Topics: Benzoquinones; Catechols; Cysteine; Flavonoids; Lysine | 2020 |
Corn silk extract inhibit the formation of N
Topics: Antioxidants; Caseins; Chromatography, High Pressure Liquid; Fatty Acids; Flavonoids; Glucose; Glyoxal; Lysine; Models, Biological; Plant Extracts; Silk; Tandem Mass Spectrometry; Zea mays | 2020 |
Formation of
Topics: Animals; Chickens; Cooking; Glycation End Products, Advanced; Lysine; Maillard Reaction | 2019 |
Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health.
Topics: Adult; Algorithms; Amino Acids, Branched-Chain; Biomarkers; Body Mass Index; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Glycation End Products, Advanced; Glycosylation; Humans; Kidney; Lysine; Male; Metabolic Diseases; Oxidation-Reduction; Severity of Illness Index; Tandem Mass Spectrometry; Tyrosine; Vascular Diseases | 2019 |
Mitochondrial carnitine palmitoyltransferase 2 is involved in N
Topics: Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glycated Hemoglobin; Humans; Kidney; Lysine; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria | 2020 |
The neurotoxicity of Nε-(carboxymethyl)lysine in food processing by a study based on animal and organotypic cell culture.
Topics: Animals; Astrocytes; Brain; Cell Culture Techniques; Cells, Cultured; Cytokines; Endothelial Cells; Endothelium, Vascular; Food Handling; Humans; Lysine; Mice; Microvessels; Neurotoxicity Syndromes; Oxidative Stress; Receptor for Advanced Glycation End Products; Transcription Factor AP-1 | 2020 |
Identification of Differential Patterns of Oxidative Biomarkers in Prostate Cancer Progression.
Topics: Aged; Aged, 80 and over; Biomarkers; Disease Progression; F2-Isoprostanes; Follow-Up Studies; Humans; Kallikreins; Lysine; Male; Middle Aged; Oxidative Stress; Prostate; Prostate-Specific Antigen; Prostatectomy; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Assessment; Watchful Waiting | 2020 |
Non-nutritive sweeteners are in concomitant with the formation of endogenous and exogenous advanced glycation end-products.
Topics: Cooking; Electrophoresis, Polyacrylamide Gel; Fructosamine; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Lysine; Non-Nutritive Sweeteners; Proof of Concept Study; Sorbitol; Sucrose; Xylitol | 2020 |
Dietary sugars and related endogenous advanced glycation end-products increase chromosomal DNA damage in WIL2-NS cells, measured using cytokinesis-block micronucleus cytome assay.
Topics: Apoptosis; Chromatography, Liquid; Chromosomal Instability; Cytokinesis; Dietary Sugars; DNA Damage; Fructose; Glucose; Glycation End Products, Advanced; Humans; Lymphocytes; Lysine; Micronucleus Tests; Serum Albumin, Bovine; Tandem Mass Spectrometry | 2020 |
The Effect of Lactobacillus fermentum ME-3 Treatment on Glycation and Diabetes Complications.
Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Gastrointestinal Microbiome; Glycated Hemoglobin; Glycation End Products, Advanced; Kidney; Limosilactobacillus fermentum; Lipids; Liver; Lysine; Male; Probiotics; Receptors, Leptin; Weight Gain | 2020 |
Evaluation of the effect of berry extracts on carboxymethyllysine and lysine in ultra-high temperature treated milk.
Topics: Animals; Food Handling; Fruit; Hot Temperature; Lysine; Milk; Plant Extracts | 2020 |
N
Topics: Amputation, Surgical; Animals; Apolipoproteins E; Atherosclerosis; Cell Movement; Cells, Cultured; Diabetic Foot; Foam Cells; Humans; Lysine; Mice; Mice, Knockout; Proto-Oncogene Proteins c-vav; rac1 GTP-Binding Protein; Signal Transduction | 2020 |
Dietary quality index is negatively associated with serum advanced glycation end products in healthy adults.
Topics: Adult; Arginine; Body Mass Index; Cross-Sectional Studies; Diet; Energy Intake; Female; Food; Glycation End Products, Advanced; Humans; Iran; Lysine; Male; Middle Aged; Nutrition Assessment | 2020 |
Immunohistochemistry of advanced glycation end product N
Topics: Adult; Aged; Atherosclerosis; Atrial Remodeling; Autopsy; Coronary Vessels; Female; Fibrosis; Forensic Pathology; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Natriuretic Peptides; Young Adult | 2020 |
Antioxidative effects of a novel dietary supplement Neumentix in a mouse stroke model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antioxidants; Brain; Cinnamates; Depsides; Dietary Supplements; Disease Models, Animal; Infarction, Middle Cerebral Artery; Lysine; Male; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Rosmarinic Acid | 2020 |
N
Topics: Animals; Chickens; Cooking; Glycation End Products, Advanced; Hot Temperature; Kinetics; Lysine; Meat Products; Water | 2021 |
Gastrointestinal digestion of dietary advanced glycation endproducts using an in vitro model of the gastrointestinal tract (TIM-1).
Topics: Animals; Arginine; Chromatography, Liquid; Digestion; Fruit and Vegetable Juices; Gastrointestinal Tract; Glycation End Products, Advanced; Glyoxal; Hepatitis A Virus Cellular Receptor 1; Humans; Lysine; Milk; Pyruvaldehyde; Tandem Mass Spectrometry; Zingiber officinale | 2020 |
Binding of CML-Modified as Well as Heat-Glycated β-lactoglobulin to Receptors for AGEs Is Determined by Charge and Hydrophobicity.
Topics: Animals; Cattle; Glycation End Products, Advanced; Glycosylation; Hot Temperature; Humans; Hydrophobic and Hydrophilic Interactions; Lactoglobulins; Lysine; Receptor for Advanced Glycation End Products | 2020 |
Simultaneous generation of acrylamide, β-carboline heterocyclic amines and advanced glycation ends products in an aqueous Maillard reaction model system.
Topics: Acrylamide; Amines; Asparagine; Carbolines; Chromatography, Gas; Chromatography, High Pressure Liquid; Glucose; Glycation End Products, Advanced; Harmine; Hot Temperature; Lysine; Maillard Reaction; Models, Biological; Pyruvaldehyde | 2020 |
Methylglyoxal-hydroimidazolones (MG-Hs) instead of Nɛ-(carboxymethyl)-l-lysine (CML) is the major advanced glycation end-product during drying process in black tea.
Topics: Camellia sinensis; Chromatography, High Pressure Liquid; Desiccation; Food Handling; Glycation End Products, Advanced; Humans; Imidazoles; Isomerism; Lysine; Plant Extracts; Plant Leaves; Pyruvaldehyde; Tandem Mass Spectrometry; Tea | 2020 |
Formation of protein-bound N
Topics: Animals; Food-Processing Industry; Glycation End Products, Advanced; Lysine; Pork Meat; Sterilization; Sugars | 2021 |
Dietary Advanced Glycation End-Products (dAGEs) Intake and Bone Health: A Cross-Sectional Analysis in the Rotterdam Study.
Topics: Aged; Bone Density; Cross-Sectional Studies; Diet; Diet Surveys; Eating; Female; Femur Neck; Glycation End Products, Advanced; Humans; Logistic Models; Lumbar Vertebrae; Lysine; Male; Middle Aged; Netherlands; Odds Ratio; Osteoporotic Fractures; Prevalence; Prospective Studies; Spinal Fractures | 2020 |
Influence of seasonal variation and processing on protein glycation and oxidation in regular and hay milk.
Topics: Animals; Cattle; Glycation End Products, Advanced; Glycosylation; Hot Temperature; Lysine; Maillard Reaction; Milk Proteins; Oxidation-Reduction; Pasteurization; Seasons | 2021 |
Dietary Intake of Nε-carboxymethyl-lysine, a Major Advanced Glycation End Product, is Not Associated with Increased Risk of Mortality in Japanese Adults in the Takayama Study.
Topics: Adult; Aged; Cohort Studies; Diet; Female; Glycation End Products, Advanced; Humans; Japan; Lysine; Male; Middle Aged; Mortality; Prospective Studies; Risk Factors | 2020 |
Free advanced glycation end product distribution in blood components and the effect of genetic polymorphisms.
Topics: Adult; Alcohol Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Chromatography, High Pressure Liquid; Erythrocytes; Female; Glycation End Products, Advanced; Healthy Volunteers; Humans; Lysine; Male; Meals; Middle Aged; Ornithine; Polymorphism, Single Nucleotide; Tandem Mass Spectrometry; Young Adult | 2020 |
The level variation of N
Topics: Chlorogenic Acid; Coffea; Coffee; Food-Processing Industry; Glycation End Products, Advanced; Hydrogen-Ion Concentration; Lysine; Seeds | 2021 |
Glyoxalase 1 expression analysis by immunohistochemistry in breast cancer.
Topics: Biomarkers, Tumor; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lactoylglutathione Lyase; Lysine; Neoplasm Recurrence, Local; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Progression-Free Survival; Receptor for Advanced Glycation End Products; Receptor, ErbB-2; Time Factors; Vascular Endothelial Growth Factor A | 2020 |
Mildly Pasteurized Whey Protein Promotes Gut Tolerance in Immature Piglets Compared with Extensively Heated Whey Protein.
Topics: Animals; Bacterial Adhesion; Digestion; Gastrointestinal Tract; Gastrointestinal Transit; Hot Temperature; Hydrogen-Ion Concentration; Immune Tolerance; Intestinal Mucosa; Lysine; Pasteurization; Permeability; Protein Aggregates; Swine; Whey Proteins | 2020 |
Pentosidine and carboxymethyl-lysine associate differently with prevalent osteoporotic vertebral fracture and various bone markers.
Topics: Aged; Aged, 80 and over; Arginine; Bone Density; Cohort Studies; Female; Glycation End Products, Advanced; Humans; Japan; Lumbar Vertebrae; Lysine; Middle Aged; Osteoporosis, Postmenopausal; Osteoporotic Fractures; Postmenopause | 2020 |
Comprehensive Quantification of Carboxymethyllysine-Modified Peptides in Human Plasma.
Topics: Diabetes Mellitus, Type 1; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Peptide Library; Peptides; Tandem Mass Spectrometry | 2021 |
Assessment the influence of salt and polyphosphate on protein oxidation and Nε-(carboxymethyl)lysine and Nε-(carboxyethyl)lysine formation in roasted beef patties.
Topics: Animals; Cattle; Food Handling; Lysine; Meat Products; Meat Proteins; Oxidation-Reduction; Polyphosphates; Sodium Chloride | 2021 |
Comparison of two kinds of peroxyl radical pretreatment at chicken myofibrillar proteins glycation on the formation of N
Topics: Animals; Chickens; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Lysine; Maillard Reaction; Meat; Muscle Proteins; Oxidation-Reduction; Peroxides; Protein Carbonylation | 2021 |
Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study.
Topics: Adult; Aged; Chromatography, Liquid; Cohort Studies; Colorectal Neoplasms; Female; Genetic Association Studies; Genetic Predisposition to Disease; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Odds Ratio; Ornithine; Tandem Mass Spectrometry | 2021 |
Effect of catechin on dietary AGEs absorption and cytotoxicity in Caco-2 cells.
Topics: Adsorption; Binding Sites; Caco-2 Cells; Catechin; Cell Survival; Down-Regulation; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Mitogen-Activated Protein Kinases; Molecular Docking Simulation; NF-kappa B; Peptide Transporter 1; Signal Transduction; Zonula Occludens-1 Protein | 2021 |
Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Glycosylation; Gold; Guanidines; Lysine; Male; Metal Nanoparticles; Proteins; Pyruvaldehyde; Rats; Rats, Wistar | 2021 |
Structural elucidation and anti-diabetic osteoporotic activity of an arabinogalactan from Phellodendron chinense Schneid.
Topics: Animals; Bone Density Conservation Agents; Diabetes Mellitus, Experimental; Galactans; Glycation End Products, Advanced; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Lysine; Male; Osteoporosis; Phellodendron; Rats, Wistar; Receptor for Advanced Glycation End Products | 2021 |
Habitual intake of dietary advanced glycation end products is not associated with generalized microvascular function-the Maastricht Study.
Topics: Aged; Biomarkers; Chromatography, Liquid; Cross-Sectional Studies; Diabetes Mellitus; Diet; Female; Glycation End Products, Advanced; Humans; Kidney; Lysine; Male; Mass Spectrometry; Microcirculation; Middle Aged; Nutritional Physiological Phenomena; Ornithine; Prospective Studies; Retinal Vessels; Skin | 2022 |
Can fingernail quality predict bone damage in Type 2 diabetes mellitus? a pilot study.
Topics: Aged; Arthroplasty, Replacement, Hip; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Femoral Neck Fractures; Femur Neck; Humans; Lysine; Middle Aged; Nails; Osteoporosis, Postmenopausal; Pilot Projects; Spectroscopy, Fourier Transform Infrared; X-Ray Microtomography | 2021 |
The Association of Nε-Carboxymethyllysine With Polyunsaturated and Saturated Fatty Acids in Healthy Individuals.
Topics: Arachidonic Acid; Biomarkers; Dietary Fats; Fatty Acids; Humans; Lysine; Stearic Acids | 2022 |
Diet-Derived Advanced Glycation End Products (dAGEs) Induce Proinflammatory Cytokine Expression in Cardiac and Renal Tissues of Experimental Mice: Protective Effect of Curcumin.
Topics: Animal Feed; Animals; Anti-Inflammatory Agents; Collagen; Curcumin; Cytokines; Diet; Gene Expression Regulation; Glycation End Products, Advanced; Inflammation Mediators; Kidney; Lysine; Male; Mice; Myocardium; Receptor for Advanced Glycation End Products | 2022 |
Biophysical and mass spectrometry based characterization of methylglyoxal-modified myoglobin: Role of advanced glycation end products in inducing protein structural alterations.
Topics: Glycation End Products, Advanced; Heme; Hydrophobic and Hydrophilic Interactions; Lysine; Mass Spectrometry; Myoglobin; Norleucine; Protein Conformation, alpha-Helical; Protein Structure, Tertiary; Pyrroles; Pyruvaldehyde | 2021 |
Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation.
Topics: Aging; Animals; Cell Line; Cell Proliferation; Endothelial Cells; Glycosylation; Glyoxal; Humans; Lysine; Methylation; Mice; Mice, Inbred C57BL; Microtubules; Primary Cell Culture; Protein Processing, Post-Translational; Proteins; Proteomics; Proteostasis; Tubulin | 2021 |
Myocardial infarction coincides with increased NOX2 and N
Topics: Aged; Biomarkers; Cerebral Arteries; Female; Humans; Immunohistochemistry; Lysine; Male; Microvessels; Middle Aged; Myocardial Infarction; NADPH Oxidase 2; Neuroinflammatory Diseases | 2021 |
Advanced glycation end-products (AGEs) are lower in prostate tumor tissue and inversely related to proportion of West African ancestry.
Topics: Age Factors; Black or African American; Correlation of Data; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Warburg Effect, Oncologic; White People | 2022 |
Advanced Glycation End-Products (AGEs) and Their Soluble Receptor (sRAGE) in Women Suffering from Systemic Lupus Erythematosus (SLE).
Topics: Arginine; Female; Glycation End Products, Advanced; Humans; Lupus Erythematosus, Systemic; Lysine; Middle Aged; Receptor for Advanced Glycation End Products | 2021 |
Exposure of
Topics: Animals; Caenorhabditis elegans; Endocytosis; Enterocytes; Gastrointestinal Tract; Glycation End Products, Advanced; Intestinal Absorption; Lysine; Models, Animal; Oxidative Stress; Protein Folding; Reproduction | 2021 |
Age-related neuronal damage by advanced glycation end products through altered proteostasis.
Topics: Aging; Animals; Autophagy-Related Protein 5; bcl-2-Associated X Protein; Brain; Brain-Derived Neurotrophic Factor; Endoplasmic Reticulum Stress; Glycation End Products, Advanced; Lysine; Neurons; Proteostasis; Pyruvaldehyde; Rats; Rats, Wistar; Ubiquitin; Unfolded Protein Response | 2022 |
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N
Topics: Animals; Gastrointestinal Microbiome; Lysine; Mice; Microglia; Oxidative Stress | 2022 |
Impaired gut barrier affects microglia health.
Topics: Gastrointestinal Microbiome; Lysine; Microglia; Oxidative Stress | 2022 |
Quantitative determination of N
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Indicators and Reagents; Isotopes; Lysine; Milk; Solid Phase Extraction; Tandem Mass Spectrometry | 2022 |
N
Topics: Animals; Cattle; Glycation End Products, Advanced; Lysine; Meat Products; Pork Meat | 2022 |
Free L-Lysine and Its Methyl Ester React with Glyoxal and Methylglyoxal in Phosphate Buffer (100 mM, pH 7.4) to Form
Topics: Esters; Gas Chromatography-Mass Spectrometry; Glycation End Products, Advanced; Glyoxal; Hydrogen-Ion Concentration; Lysine; Magnesium Oxide; Phosphates; Pyruvaldehyde; Schiff Bases | 2022 |
Plasma Levels of Free
Topics: Animals; Biomarkers; Breakfast; Chromatography, Liquid; Glycation End Products, Advanced; Humans; Lysine; Rats; Receptor for Advanced Glycation End Products; Tandem Mass Spectrometry | 2022 |
Correlation Analysis of CML, sRAGE, and esRAGE and the Measure of Atherosclerosis of Coronary Heart Disease.
Topics: Atherosclerosis; Biomarkers; Coronary Disease; Glycation End Products, Advanced; Humans; Lysine; Receptor for Advanced Glycation End Products | 2022 |
High serum levels of N-epsilon-carboxymethyllysine are associated with poor coronary collateralization in type 2 diabetic patients with chronic total occlusion of coronary artery.
Topics: Collateral Circulation; Coronary Angiography; Coronary Circulation; Coronary Occlusion; Coronary Vessels; Diabetes Mellitus, Type 2; Humans; Lysine | 2022 |
Diabetic nephropathy patients show hyper-responsiveness to N6-carboxymethyllysine.
Topics: Culture Media, Conditioned; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Lysine; NF-kappa B | 2022 |
Inter- and Intraindividual Differences in the Capacity of the Human Intestinal Microbiome in Fecal Slurries to Metabolize Fructoselysine and Carboxymethyllysine.
Topics: Feces; Gastrointestinal Microbiome; Glycation End Products, Advanced; Humans; Lysine; RNA, Ribosomal, 16S | 2022 |
Anti-Inflammatory Activity of CIGB-258 against Acute Toxicity of Carboxymethyllysine in Paralyzed Zebrafish via Enhancement of High-Density Lipoproteins Stability and Functionality.
Topics: Animals; Anti-Inflammatory Agents; COVID-19; Inflammation; Infliximab; Lipoproteins, HDL; Lysine; Paralysis; Zebrafish | 2022 |
Comparison of tissue distribution of free and protein bound Nɛ-carboxymethyllysine after long-term oral administration to mice.
Topics: Administration, Oral; Animals; Glycation End Products, Advanced; Lysine; Mice; Proteins; Tissue Distribution | 2022 |
Glyoxal-derived advanced glycation end-products, N
Topics: Apoptosis; Gene Expression; Glycation End Products, Advanced; Glyoxal; Hepatocytes; Humans; Lysine; Maillard Reaction; Proteins; Pyruvaldehyde; Reactive Oxygen Species | 2023 |
The Maillard reaction end product
Topics: Animals; Creatinine; Diet; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction | 2023 |
Comparison of pharmacokinetics, biodistribution, and excretion of free and bound Nε-carboxymethyllysine in rats by HPLC-MS/MS.
Topics: Animals; Chromatography, High Pressure Liquid; Lysine; Rats; Serum Albumin, Bovine; Tandem Mass Spectrometry; Tissue Distribution | 2023 |
Magnetically Controlled Nanorobots Based on Red Emissive Peptide Dots and Artificial Antibodies for Specific Recognition and Smart Scavenging of
Topics: Antibodies; Dairy Products; Glycation End Products, Advanced; Lysine; Peptides; Reproducibility of Results | 2023 |
The Effect of Free and Protein-Bound Maillard Reaction Products N-ε-Carboxymethyllysine, N-ε-Fructosyllysine, and Pyrraline on Nrf2 and NFκB in HCT 116 Cells.
Topics: Caseins; Chromatography, Liquid; Glycation End Products, Advanced; HCT116 Cells; Humans; Lysine; Maillard Reaction; NF-E2-Related Factor 2; Receptor for Advanced Glycation End Products; Tandem Mass Spectrometry | 2023 |
Nε-Carboxymethyl-Lysine Modification of Extracellular Matrix Proteins Augments Fibroblast Activation.
Topics: Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Glycation End Products, Advanced; Humans; Idiopathic Pulmonary Fibrosis; Lysine | 2023 |
Effect of edible oil type on the formation of protein-bound N
Topics: Animals; Corn Oil; Glyoxal; Humans; Linoleic Acid; Linolenic Acids; Linseed Oil; Lysine; Oleic Acid; Olive Oil; Palmitic Acid; Plant Oils; Pork Meat; Red Meat; Swine; Tandem Mass Spectrometry | 2023 |