Page last updated: 2024-08-17

lysine and mocetinostat

lysine has been researched along with mocetinostat in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.82)18.7374
1990's11 (20.00)18.2507
2000's26 (47.27)29.6817
2010's14 (25.45)24.3611
2020's3 (5.45)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Clark, RA; Kagan, HM; Szot, S; Williams, MA1
Bourdon, DM; Currie, MG; Manning, PT; Marino, MH; Salvemini, D; Wang, ZQ; Wyatt, PS1
Anderson, MM; Hazen, SL; Heinecke, JW; Hsu, FF1
Crowley, JR; d'Avignon, A; Gaut, JP; Hazen, SL; Heinecke, JW; Hsu, FF1
Bandyopadhyay, D; Banerjee, RK; Das, D1
Anderson, MM; d'Avignon, A; Hazen, SL; Heinecke, JW; Hsu, FF1
Aoki, C; Erişir, A1
Crowley, JR; Gaut, JP; Hazen, SL; Heinecke, JW; Hsu, FF2
Finch, AM; Monk, PN; Sanderson, SD; Taylor, SM; Thatcher, J; Vogen, SM; Wadi, SK1
Davies, MJ; Hazell, LJ; Stocker, R1
Anderson, MM; Crowley, JR; Heinecke, JW; Requena, JR; Thorpe, SR1
Monnier, VM; Obrenovich, M; Saxena, AK; Saxena, P; Weiss, MF; Wu, X1
Bechtold, U; Fuchsbauer, HL; Otterbach, JT; Pasternack, R1
De Cristofaro, R; Landolfi, R1
Borja-Oliveira, CR; Fontes, MR; Giglio, JR; Guerra-Sá, R; Gutiérrez, JM; Lomonte, B; Rodrigues, V; Rodrigues, VM; Rodrigues-Simioni, L; Soares, AM1
Bani, D; Bani-Sacchi, T; Baronti, R; Bigazzi, M; Mannaioni, PF; Masini, E; Sardi, I1
Lai, PS; Lin, KT; Linask, KK; Liu, X; Nagele, RG; Sun, FF; Wang, C; Wong, PY; Yin, K; Yue, G1
Geczy, CL; Raftery, MJ; Valenzuela, SM; Yang, Z1
Fu, X; Heinecke, JW; Mueller, DM1
Chen, CS; Huang, KL; Kang, BH; Lu, MY; Wan, FJ1
Auchère, F; Capeillère-Blandin, C1
Bárány, P; Heimburger, O; Hoff, CM; Holmes, CJ; Lindholm, B; Marchlewska, A; Nordfors, L; Pecoits-Filho, R; Schalling, M; Stenvinkel, P; Suliman, M1
Aratani, Y; Furuhata, A; Kawai, Y; Toyokuni, S; Uchida, K1
Cho, EJ; Rhyu, DY; Yokozawa, T1
Harkin, DW; Lindsay, TF; Romaschin, A; Rubin, BB1
Dawson, TM; Dawson, VL; Jiménez, N; Pol, O; Puig, MM; Sasaki, M1
Allen, SJ; Cox, CS; Laine, GA; Moore, FA; Moore-Olufemi, SD; Stewart, RH; Xue, H1
Fu, X; Green, PS; Heinecke, JW; McDonald, TO; O'Brien, KD; Oram, JF; Shao, B; Uchida, K1
Babar, S; Boudjeltia, KZ; Ducobu, J; Legssyer, I; Moguilevsky, N; Moreau, P; Nève, J; Van Antwerpen, P; Vanhaeverbeek, M1
Albert, CJ; Ford, DA; Hsu, FF; Kao, JL; Wildsmith, KR1
Bergt, C; Brot, N; Fu, X; Green, PS; Heinecke, JW; Oda, MN; Oram, JF; Shao, B1
Baidoshvili, A; Bleeker, W; Ciurana, C; Eijsman, L; Hack, CE; Krijnen, PA; Kupreishvili, K; Meijer, CJ; Niessen, HW; Nijmeijer, R; Schalkwijk, CG; Stooker, W; van Hinsbergh, VW; Visser, CA; Visser, FC1
Awad, H; Cardounel, AJ; Chen, Z; Christofi, FL; Cooke, H; Guzman, J; Hassanain, HH; Javed, A; Palmer, J; Suntres, Z; Xue, J; Yu, JG1
Ischiropoulos, H; Rader, DJ1
Alipour, M; Omri, A; Smith, MG; Suntres, ZE1
Brubaker, G; Hazen, SL; Kinter, M; Peng, DQ; Smith, JD; Willard, B; Wu, Z; Zheng, L1
Almac, E; Bezemer, R; Ince, C; Johannes, T; Kandil, A; Legrand, M; Mik, EG; Payen, D1
Cevik-Aras, H; Ekström, J1
Dai, HJ; Dobson, RL; Foertsch, LM; Gerberick, GF; Kern, PS; Lalko, JF; Lepoittevin, JP; Quijano, M; Troutman, JA1
Binder, V; Curcic, S; El-Gamal, D; Heinemann, A; Holzer, M; Konya, V; Marsche, G; Schuligoi, R; Zangger, K1
Delporte, C; Desmet, JM; Dufour, D; Franck, T; Madhoun, P; Moguilevsky, N; Nève, J; Nortier, J; Noyon, C; Raes, M; Rousseau, A; Serteyn, D; Van Antwerpen, P; Vanhaeverbeek, M; Vanhamme, L; Zouaoui Boudjeltia, K1
Coletta, M; Di Pierro, D; Droghetti, E; Fiorucci, L; Howes, BD; Piro, MC; Polticelli, F; Santucci, R; Sinibaldi, F; Smulevich, G1
Chen, X; Wei, JL; Wu, JX; Xu, MY; Zhang, XF; Zhu, HW1
Goodwin, DC; Huang, J; Panizzi, JR; Panizzi, P; Smith, F1
Aikawa, H; Eto, A; Hanada, H; Hiraoka, F; Iko, M; Inoue, R; Kazekawa, K; Kiyomi, F; Mitsutake, T; Nagai, R; Nii, K; Sakamoto, K; Sakata, N; Shirakawa, JI; Tsutsumi, M1
Osawa, T1
Cutrupi, S; Mallamaci, F; Pizzini, P; Torino, C; Tripepi, G; Tripepi, R; Vilasi, A; Zoccali, C1
Bonini, M; Brien, JO; Dean, AE; Gao, Y; Gius, D; Hart, R; Horikoshi, N; Jiang, H; Kieffer, MB; Liu, G; Park, SH; Quan, S; Satchell, KJF; Stauffer, ME; Tran, EL; Zhu, Y; Zou, X1
He, Y; Shen, Y; Zhang, C1
Cao, G; Han, D; Meng, J; Wang, H; Yu, W; Zhang, Y1
Sato, S1
Bazylianska, V; Brunzelle, JS; Chowdhury, DD; Edwards, BFP; Heath, EI; Hüttemann, M; Kalpage, HA; Kim, K; Lee, I; Mahapatra, G; Marcus, K; Morse, PT; Podgorski, I; Polin, L; Subedi, P; Turner, AA; Vaishnav, A; Wan, J1
Alshehri, B1

Reviews

2 review(s) available for lysine and mocetinostat

ArticleYear
Development and application of oxidative stress biomarkers.
    Bioscience, biotechnology, and biochemistry, 2018, Volume: 82, Issue:4

    Topics: Biomarkers; DNA; Dopamine; Functional Food; Humans; Inflammation; Lipid Peroxidation; Lipid Peroxides; Lysine; Oxidative Stress; Peroxidase; Phospholipids; Reactive Oxygen Species; Tyrosine

2018
[Development and Application of Catalytic Tyrosine Chemical Modification].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:11

    Topics: Catalysis; Cysteine; Electron Transport; Electrons; Hemin; Luminol; Lysine; Oxidation-Reduction; Peroxidase; Proteins; Ruthenium; Tyrosine

2019

Trials

1 trial(s) available for lysine and mocetinostat

ArticleYear
Effect of Vitamin D Receptor Activation on the AGE/RAGE System and Myeloperoxidase in Chronic Kidney Disease Patients.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Aged; Arginine; Ergocalciferols; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Peroxidase; Receptor for Advanced Glycation End Products; Receptors, Calcitriol; Renal Insufficiency, Chronic; S100A12 Protein

2017

Other Studies

52 other study(ies) available for lysine and mocetinostat

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Oxidation of lysine side-chains of elastin by the myeloperoxidase system and by stimulated human neutrophils.
    Biochemical and biophysical research communications, 1986, Mar-13, Volume: 135, Issue:2

    Topics: Animals; Cell-Free System; Chlorides; Dogs; Elastin; Humans; Hydrogen Peroxide; In Vitro Techniques; Iodides; Lysine; Neutrophils; Oxidation-Reduction; Peroxidase; Tetradecanoylphorbol Acetate

1986
Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation.
    British journal of pharmacology, 1996, Volume: 118, Issue:4

    Topics: Animals; Carrageenan; Dinoprostone; Edema; Enzyme Inhibitors; Excipients; Free Radical Scavengers; Guanidines; Hindlimb; Inflammation; Isoenzymes; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

1996
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated
    The Journal of clinical investigation, 1997, Feb-01, Volume: 99, Issue:3

    Topics: Acetaldehyde; Acrolein; Aldehydes; Amino Acids; Catalase; Chlorides; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Heme; Humans; Hydrogen Peroxide; Hydroxy Acids; Hypochlorous Acid; Inflammation; Lysine; Mass Spectrometry; Molecular Structure; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Serine; Threonine

1997
p-Hydroxyphenylacetaldehyde, the major product of L-tyrosine oxidation by the myeloperoxidase-H2O2-chloride system of phagocytes, covalently modifies epsilon-amino groups of protein lysine residues.
    The Journal of biological chemistry, 1997, Jul-04, Volume: 272, Issue:27

    Topics: Acetaldehyde; Amino Acids; Animals; Cattle; Chlorides; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Inflammation; Lysine; Magnetic Resonance Spectroscopy; Neutrophils; Peroxidase; Phagocytes; Phenol; Proteins; Schiff Bases; Serum Albumin, Bovine; Tyrosine

1997
Oxidative inactivation of gastric peroxidase by site-specific generation of hydroxyl radical and its role in stress-induced gastric ulceration.
    Free radical biology & medicine, 1998, Volume: 24, Issue:3

    Topics: Animals; Ascorbic Acid; Cold Temperature; Copper; Free Radical Scavengers; Gastric Mucosa; Heme; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Lysine; Oxidation-Reduction; Peroxidase; Rats; Rats, Wistar; Reactive Oxygen Species; Restraint, Physical; Stomach Ulcer; Stress, Physiological

1998
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway.
    The Journal of biological chemistry, 1998, Feb-27, Volume: 273, Issue:9

    Topics: Aldehydes; Amino Acids; Chloramines; Chlorides; Humans; Hypochlorous Acid; Lysine; Mass Spectrometry; Models, Chemical; Neutrophils; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine

1998
A method of combining biocytin tract-tracing with avidin-biotin-peroxidase complex immunocytochemistry for pre-embedding electron microscopic labeling in neonatal tissue.
    Journal of neuroscience methods, 1998, Jun-01, Volume: 81, Issue:1-2

    Topics: Animals; Animals, Newborn; Avidin; Axonal Transport; Binding Sites; Biotin; Brain; Cats; Caudate Nucleus; Immunohistochemistry; Lysine; Microscopy, Electron; Neural Pathways; Peroxidase; Putamen; Rats; Silver Staining; Thalamus; Tissue Embedding; Visual Cortex

1998
Modification of proteins and lipids by myeloperoxidase.
    Methods in enzymology, 1999, Volume: 300

    Topics: Arteries; Arteriosclerosis; Biomarkers; Chlorine; Cholesterol, LDL; Female; Gas Chromatography-Mass Spectrometry; Humans; Lipoproteins, LDL; Lysine; Male; Oxidation-Reduction; Peroxidase; Sodium Hypochlorite

1999
The influence of Lys68 in decepeptide agonists of C5a on C5a receptor binding, activation and selectivity.
    The journal of peptide research : official journal of the American Peptide Society, 1999, Volume: 53, Issue:1

    Topics: Antigens, CD; Cells, Cultured; Complement C5a; Humans; Lysine; Muscle Contraction; Muscle, Smooth, Vascular; Mutation; Oligopeptides; Peptide Fragments; Peroxidase; Protein Binding; Receptor, Anaphylatoxin C5a; Receptors, Complement; Serotonin; Transfection

1999
Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins.
    The Biochemical journal, 1999, May-01, Volume: 339 ( Pt 3)

    Topics: Apolipoprotein B-100; Apolipoproteins B; Chloramines; Chlorides; Cholesterol Esters; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Electrons; Female; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hypochlorous Acid; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Male; Methionine; Oxidants; Peroxidase; Tryptophan; Vitamin E

1999
The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation.
    The Journal of clinical investigation, 1999, Volume: 104, Issue:1

    Topics: Aldehydes; Catalase; Cations; Cells, Cultured; Chelating Agents; Glycosylation; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Lysine; Maillard Reaction; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Processing, Post-Translational; Ribonuclease, Pancreatic; Serine; Sodium Azide

1999
Protein aging by carboxymethylation of lysines generates sites for divalent metal and redox active copper binding: relevance to diseases of glycoxidative stress.
    Biochemical and biophysical research communications, 1999, Jul-05, Volume: 260, Issue:2

    Topics: Animals; Ascorbic Acid; Binding Sites; Biopolymers; Catalysis; Cations, Divalent; Collagen; Copper; Diabetes Mellitus, Experimental; Free Radicals; Glycation End Products, Advanced; Humans; Hydrogen Peroxide; Kidney Failure, Chronic; Lysine; Methylation; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Serine

1999
Enzymic preparation of protein G-peroxidase conjugates catalysed by transglutaminase.
    Journal of biochemistry, 2000, Volume: 127, Issue:2

    Topics: Cadaverine; Dipeptides; Enzyme-Linked Immunosorbent Assay; Fluorescent Dyes; Glutamine; Glycine max; Lysine; Nerve Tissue Proteins; Peroxidase; Protein Engineering; Recombinant Proteins; Staphylococcal Protein A; Substrate Specificity; Sulfonamides; Transglutaminases

2000
Oxidation of human alpha-thrombin by the myeloperoxidase-H2O2-chloride system: structural and functional effects.
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:2

    Topics: Amino Acid Sequence; Antithrombin III; Blood Platelets; Chlorides; Chromatography, High Pressure Liquid; Fibrinopeptide A; Fibrinopeptide B; Hemostatics; Heparin; Humans; Hydrogen Peroxide; Hydrolysis; Hypochlorous Acid; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptides; Peroxidase; Platelet Activation; Protein C; Pyridoxal Phosphate; Structure-Activity Relationship; Substrate Specificity; Thrombin; Thrombomodulin

2000
Structural and functional characterization of BnSP-7, a Lys49 myotoxic phospholipase A(2) homologue from Bothrops neuwiedi pauloensis venom.
    Archives of biochemistry and biophysics, 2000, Jun-15, Volume: 378, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Bothrops; Chickens; Crotalid Venoms; DNA, Complementary; Dose-Response Relationship, Drug; Edema; Escherichia coli; Group II Phospholipases A2; Heparin; Lysine; Male; Mice; Molecular Sequence Data; Muscle, Skeletal; Neurotoxins; Peroxidase; Phospholipases A; Reptilian Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Temperature; Time Factors; X-Ray Diffraction

2000
Dual role of nitric oxide in myocardial ischemia-reperfusion.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49 Suppl 1

    Topics: Animals; Enzyme Inhibitors; Lysine; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Wistar; Relaxin

2000
Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions.
    The Biochemical journal, 2000, Dec-15, Volume: 352 Pt 3

    Topics: Acetaldehyde; Antioxidants; Aorta; Arteriosclerosis; Chlorides; Gas Chromatography-Mass Spectrometry; Humans; Lipid Metabolism; Lipoproteins, LDL; Lysine; Peroxidase; Phenol; Schiff Bases; Solubility; Tunica Intima; Tyrosine; Water

2000
Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Death; Colitis; Colon; Disease Models, Animal; Epithelial Cells; Immunohistochemistry; In Situ Nick-End Labeling; Isoenzymes; Lysine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxides; Trinitrobenzenesulfonic Acid; Tyrosine

2001
Novel intra- and inter-molecular sulfinamide bonds in S100A8 produced by hypochlorite oxidation.
    The Journal of biological chemistry, 2001, Sep-07, Volume: 276, Issue:36

    Topics: Amino Acid Sequence; Antigens, Differentiation; Aspartic Acid; Binding Sites; Calcium-Binding Proteins; Calgranulin A; Chromatography, High Pressure Liquid; Cyclohexanones; Cysteine; Dimerization; Disulfides; Dithiothreitol; Dose-Response Relationship, Drug; Hydrogen Peroxide; Hypochlorous Acid; Lysine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Neutrophils; Oxygen; Peptides; Peroxidase; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfenic Acids; Sulfur; Tetradecanoylphorbol Acetate; Time Factors

2001
Generation of intramolecular and intermolecular sulfenamides, sulfinamides, and sulfonamides by hypochlorous acid: a potential pathway for oxidative cross-linking of low-density lipoprotein by myeloperoxidase.
    Biochemistry, 2002, Jan-29, Volume: 41, Issue:4

    Topics: Amides; Amino Acid Sequence; Chromatography, High Pressure Liquid; Hypochlorous Acid; Lipoproteins, LDL; Lysine; Oligopeptides; Oxidation-Reduction; Peroxidase; Spectrometry, Mass, Electrospray Ionization; Sulfur Compounds

2002
Hyperbaric oxygen attenuates lipopolysaccharide-induced acute lung injury.
    Intensive care medicine, 2002, Volume: 28, Issue:5

    Topics: Analysis of Variance; Animals; Bronchoalveolar Lavage; Hyperbaric Oxygenation; Injections, Intraperitoneal; Lipopolysaccharides; Lung; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Rats; Rats, Sprague-Dawley

2002
Oxidation of Cu, Zn-superoxide dismutase by the myeloperoxidase/hydrogen peroxide/chloride system: functional and structural effects.
    Free radical research, 2002, Volume: 36, Issue:11

    Topics: Animals; Cattle; Copper; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Hydrazines; Hydrogen Peroxide; Hypochlorous Acid; Isoelectric Focusing; Lysine; Methionine; Oxidation-Reduction; Peroxidase; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase; Tyrosine; Zinc

2002
A functional variant of the myeloperoxidase gene is associated with cardiovascular disease in end-stage renal disease patients.
    Kidney international. Supplement, 2003, Issue:84

    Topics: Arginine; Arteriosclerosis; Chlamydia Infections; Chlamydophila pneumoniae; Diabetic Nephropathies; Female; Genotype; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Oxidative Stress; Peroxidase; Polymorphism, Single Nucleotide; Risk Factors

2003
Formation of acrolein-derived 2'-deoxyadenosine adduct in an iron-induced carcinogenesis model.
    The Journal of biological chemistry, 2003, Dec-12, Volume: 278, Issue:50

    Topics: Acrolein; Aldehydes; Animals; Antibodies, Monoclonal; Binding, Competitive; Cattle; Cell Nucleus; Deoxyadenosines; DNA Adducts; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Ions; Iron; Lipid Peroxidation; Liver; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Chemical; Neoplasms; Oxidative Stress; Oxygen; Peroxidase; Rats; Rats, Wistar; Threonine; Thymus Gland; Time Factors

2003
(-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:2

    Topics: Animals; Azoles; Blood Urea Nitrogen; Catechin; Copper; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Isoindoles; Japan; Kidney; Lipopolysaccharides; Lysine; Male; Nitric Oxide; Organoselenium Compounds; Peroxidase; Phytotherapy; Plant Extracts; Plant Roots; Proteinuria; Rats; Rats, Wistar; Reperfusion Injury; Rheum; Superoxide Dismutase; Tyrosine; Uric Acid; Zinc

2004
Selective inducible nitric oxide synthase (iNOS) inhibition attenuates remote acute lung injury in a model of ruptured abdominal aortic aneurysm.
    The Journal of surgical research, 2004, Volume: 120, Issue:2

    Topics: Acute Disease; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Blood Pressure; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Interleukin-6; Intestinal Mucosa; Lung; Lung Diseases; Lysine; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osmolar Concentration; Permeability; Peroxidase; Rats; Rats, Sprague-Dawley; Receptor, Anaphylatoxin C5a; Resuscitation; RNA, Messenger; Tumor Necrosis Factor-alpha

2004
The involvement of nitric oxide in the enhanced expression of mu-opioid receptors during intestinal inflammation in mice.
    British journal of pharmacology, 2005, Volume: 145, Issue:6

    Topics: Animals; Croton Oil; Enteritis; Gastrointestinal Transit; Gene Expression Regulation; Jejunum; Lysine; Male; Mice; Mice, Knockout; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Receptors, Opioid, mu; RNA, Messenger

2005
Inhibition of intestinal transit by resuscitation-induced gut edema is reversed by L-NIL.
    The Journal of surgical research, 2005, Volume: 129, Issue:1

    Topics: Animals; Blotting, Western; Body Water; Edema; Enzyme Inhibitors; Fluorescent Dyes; Gastrointestinal Transit; Ileus; Intestinal Diseases; Lysine; Male; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley; Resuscitation

2005
Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I.
    The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43

    Topics: Acrolein; Adenosine Triphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Apolipoprotein A-I; Arteries; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Blotting, Western; Cholesterol; Chromatography, Liquid; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Inflammation; Lipid Peroxidation; Lipoproteins, HDL; Lysine; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Peptides; Peroxidase; Phospholipids; Protein Structure, Secondary; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Threonine; Time Factors

2005
Thiol-containing molecules interact with the myeloperoxidase/H2O2/chloride system to inhibit LDL oxidation.
    Biochemical and biophysical research communications, 2005, Nov-11, Volume: 337, Issue:1

    Topics: Acetylcysteine; Antioxidants; Captopril; Chlorides; Flufenamic Acid; Glutathione; Hydrogen Peroxide; Lipoproteins, LDL; Lysine; Oxidation-Reduction; Peroxidase; Sulfhydryl Compounds

2005
Myeloperoxidase-derived 2-chlorohexadecanal forms Schiff bases with primary amines of ethanolamine glycerophospholipids and lysine.
    Chemistry and physics of lipids, 2006, Volume: 139, Issue:2

    Topics: Aldehydes; Amines; Chemical Phenomena; Chemistry, Physical; Coronary Vessels; Endothelial Cells; Humans; Hydrolysis; Lysine; Molecular Structure; Peroxidase; Phosphatidylethanolamines; Schiff Bases; Time Factors

2006
Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I.
    The Journal of biological chemistry, 2006, Apr-07, Volume: 281, Issue:14

    Topics: Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol, HDL; Foam Cells; Humans; Lysine; Methionine; Methionine Sulfoxide Reductases; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Peroxidase; Protein Binding; Tyrosine

2006
N(epsilon)-(carboxymethyl)lysine depositions in intramyocardial blood vessels in human and rat acute myocardial infarction: a predictor or reflection of infarction?
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:11

    Topics: Aged; Animals; Coronary Vessels; E-Selectin; Endothelial Cells; Female; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Myocarditis; Oxidative Stress; Peroxidase; Prognosis; Rats; Risk Factors; Time Factors

2006
Cyclic AMP signaling contributes to neural plasticity and hyperexcitability in AH sensory neurons following intestinal Trichinella spiralis-induced inflammation.
    International journal for parasitology, 2007, Volume: 37, Issue:7

    Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dideoxyadenosine; Dinoprostone; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Lysine; Male; Membrane Potentials; Muscle, Smooth; Neuronal Plasticity; Neurons, Afferent; Nitric Oxide; Peroxidase; Signal Transduction; Substance P; Thiobarbituric Acid Reactive Substances; Trichinella spiralis; Trichinellosis; Tryptases

2007
'Multipurpose oxidase' in atherogenesis.
    Nature medicine, 2007, Volume: 13, Issue:10

    Topics: Animals; Apoptosis; Atherosclerosis; Carbamates; Cardiovascular Diseases; Cell Proliferation; Citrulline; Endothelial Cells; Humans; Inflammation; Lipoproteins, HDL; Lipoproteins, LDL; Lysine; Macrophages; Mice; Models, Biological; Muscle, Smooth; Oxidation-Reduction; Peroxidase; Scavenger Receptors, Class A; Smoking; Substrate Specificity; Thiocyanates

2007
Prophylactic effect of liposomal N-acetylcysteine against LPS-induced liver injuries.
    Journal of endotoxin research, 2007, Volume: 13, Issue:5

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Chloramines; Disease Models, Animal; Lipid Peroxidation; Lipopolysaccharides; Liver; Lysine; Male; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha

2007
Apolipoprotein A-I tryptophan substitution leads to resistance to myeloperoxidase-mediated loss of function.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:11

    Topics: Amino Acid Substitution; Animals; Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cell Line; Cholesterol; Humans; Hydrogen Peroxide; Lysine; Macrophages; Methionine; Mice; Mutagenesis, Site-Directed; Oxidation-Reduction; Peroxidase; Recombinant Proteins; Tryptophan

2008
L-NIL prevents renal microvascular hypoxia and increase of renal oxygen consumption after ischemia-reperfusion in rats.
    American journal of physiology. Renal physiology, 2009, Volume: 296, Issue:5

    Topics: Animals; Enzyme Inhibitors; Hypoxia; Kidney; Lysine; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Oxygen Consumption; Peroxidase; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Sodium

2009
Anti-inflammatory action of cholecystokinin and melatonin in the rat parotid gland.
    Oral diseases, 2010, Volume: 16, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Escherichia coli; Hormone Antagonists; Injections, Intraperitoneal; Lipopolysaccharides; Lysine; Melatonin; Neutrophil Infiltration; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Organ Size; Parasympathectomy; Parotid Gland; Parotitis; Peroxidase; Proglumide; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptor, Melatonin, MT2; Sincalide; Sympathectomy; Tryptamines

2010
The incorporation of lysine into the peroxidase peptide reactivity assay for skin sensitization assessments.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 122, Issue:2

    Topics: Allergens; Animal Use Alternatives; Chromatography, High Pressure Liquid; Cysteine; Dermatitis, Allergic Contact; Haptens; Humans; Lysine; Peptides; Peroxidase; Risk Assessment; Skin; Skin Tests; Tandem Mass Spectrometry; Toxicity Tests

2011
Myeloperoxidase-derived chlorinating species induce protein carbamylation through decomposition of thiocyanate and urea: novel pathways generating dysfunctional high-density lipoprotein.
    Antioxidants & redox signaling, 2012, Oct-15, Volume: 17, Issue:8

    Topics: Antioxidants; Chlorine; Humans; Hypochlorous Acid; Lipoproteins, HDL; Lysine; Peroxidase; Thiocyanates; Urea

2012
Simultaneous measurement of protein-bound 3-chlorotyrosine and homocitrulline by LC-MS/MS after hydrolysis assisted by microwave: application to the study of myeloperoxidase activity during hemodialysis.
    Talanta, 2012, Sep-15, Volume: 99

    Topics: Aged; Aged, 80 and over; Animals; Blood Chemical Analysis; Blood Proteins; Chromatography, Liquid; Citrulline; Female; Humans; Hydrolysis; Lysine; Male; Microwaves; Middle Aged; Peroxidase; Renal Dialysis; Tandem Mass Spectrometry; Time Factors; Tyrosine

2012
Role of lysines in cytochrome c-cardiolipin interaction.
    Biochemistry, 2013, Jul-02, Volume: 52, Issue:26

    Topics: Animals; Apoptosis; Cardiolipins; Cytochromes c; Horses; Humans; Lysine; Myocardium; Peroxidase; Protein Binding; Protein Interaction Maps; Protein Structure, Tertiary

2013
Inducible nitric oxide synthase inhibition reverses pulmonary arterial dysfunction in lung transplantation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2014, Volume: 63, Issue:8

    Topics: Animals; In Vitro Techniques; Lung; Lung Transplantation; Lysine; Male; Malondialdehyde; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase; Phenylephrine; Pulmonary Artery; Rats, Sprague-Dawley; Reperfusion Injury; Vasoconstriction; Vasodilation

2014
Inactivation of myeloperoxidase by benzoic acid hydrazide.
    Archives of biochemistry and biophysics, 2015, Mar-15, Volume: 570

    Topics: Amino Acid Sequence; Aniline Compounds; Animals; Benzoic Acid; Carbocyanines; Catalytic Domain; Cattle; Electrons; Enzyme Inhibitors; Fluorescent Dyes; Free Radicals; Glutamic Acid; Heme; Humans; Hydrogen Peroxide; Inflammation; Lysine; Mass Spectrometry; Methionine; Molecular Conformation; Molecular Sequence Data; Neutrophils; Oxygen; Peroxidase; Spectrometry, Fluorescence

2015
N
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:6

    Topics: Aged; Aged, 80 and over; Biomarkers; Carotid Arteries; Carotid Stenosis; Chi-Square Distribution; Chromatography, Liquid; Diffusion Magnetic Resonance Imaging; Embolic Protection Devices; Endovascular Procedures; Enzyme-Linked Immunosorbent Assay; Female; Humans; Linear Models; Lysine; Magnetic Resonance Angiography; Male; Molecular Imaging; Multivariate Analysis; Peroxidase; Plaque, Atherosclerotic; Predictive Value of Tests; Registries; Risk Assessment; Risk Factors; Stents; Tandem Mass Spectrometry; Treatment Outcome

2017
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter.
    Nature communications, 2019, 06-03, Volume: 10, Issue:1

    Topics: Acetylation; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Disease Progression; Drug Resistance, Neoplasm; Humans; In Vitro Techniques; Lysine; MCF-7 Cells; Mice; Mutation; Neoplasm Transplantation; Peroxidase; Protein Structure, Quaternary; Reactive Oxygen Species; Superoxide Dismutase; Tamoxifen; Tumor Suppressor Proteins

2019
L-Lysine protects against sepsis-induced chronic lung injury in male albino rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 117

    Topics: Animals; Antioxidants; Biomarkers; Cell Count; Chronic Disease; Glutathione; Glutathione Peroxidase; Inflammation Mediators; Lipid Peroxidation; Lung; Lung Injury; Lysine; Male; Peroxidase; Protective Agents; Rats; Sepsis; Superoxide Dismutase

2019
L-lysine ameliorates sepsis-induced acute lung injury in a lipopolysaccharide-induced mouse model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 118

    Topics: Acute Lung Injury; Animals; Cell Count; Cytokines; Disease Models, Animal; Glutathione; Lipid Peroxidation; Lipopolysaccharides; Lung; Lysine; Mice; Organ Size; Peroxidase; Sepsis; Superoxide Dismutase

2019
Lysine 53 Acetylation of Cytochrome
    Cells, 2021, 04-03, Volume: 10, Issue:4

    Topics: Acetylation; Animals; Apoptosis; Cardiolipins; Caspase 3; Cell Line, Tumor; Crystallography, X-Ray; Cytochromes c; Electron Transport Complex IV; Humans; Lysine; Male; Mice; Molecular Dynamics Simulation; Mutation; Oxidation-Reduction; Oxygen Consumption; Peroxidase; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Reactive Oxygen Species; Warburg Effect, Oncologic; Xenograft Model Antitumor Assays

2021
Expression patterns and therapeutic implications of histone deacetylase-1 across carcinomas: a comprehensive molecular docking and MD simulation study.
    Medical oncology (Northwood, London, England), 2022, Sep-29, Volume: 39, Issue:12

    Topics: Benzamides; Carcinoma; Histone Deacetylases; Histones; Humans; Lysine; Molecular Docking Simulation; Pyrimidines

2022