lysine has been researched along with leupeptins in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (13.79) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 12 (41.38) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Arzadon, L; Boreisha, IG; Robbins, KC; Summaria, L | 1 |
| Charlwood, PA; Chindemi, PA; Regoeczi, E | 1 |
| Carlino, JA; Niu, EM; Sherman, MR; Stevens, YW; Tuazon, FB | 1 |
| Fujii, S; Hitomi, Y; Honda, T; Niinobe, M | 1 |
| Eastman, S; Freed, DC; Goldrath, AW; Morkowski, S; Ramachandra, L; Whiteley, P | 1 |
| Caput, D; Dumont, X; Kaghad, M; Minty, A | 1 |
| Baba, H; Kamaguch, A; Nakayama, K; Ohyama, T; Okamoto, M; Watanabe, T | 1 |
| Aharon, M; Dvilansky, A; Nathan, I; Shpilberg, O | 1 |
| He, K; Hu, MR; Jin, BF; Lan, Y; Shen, BF; Wang, HX; Wang, J; Wei, KH; Yang, SC; Zhang, XM; Zhou, T | 1 |
| Floyd, ZE; Stephens, JM | 1 |
| Bonjardim, CA; Brasil, BS; De Sousa, LP; Ferreira, PC; Freitas, MH; Kroon, EG; Nogueira, SV; Silva, BM | 1 |
| El-mahdy, M; Snapka, RM; Wang, QE; Wani, AA; Wani, G; Zhu, Q | 1 |
| Arvan, P; Bae, JH; Hossain, SA; Jongsamak, P; Kim, PS; Lee, J; Li, B; Menon, S; Panijpan, B | 1 |
| Kim, OJ | 1 |
| Bartenschlager, R; Breton, V; Jirasko, V; Pause, A; Penin, F; Reiss, S; Welbourn, S | 1 |
| Hardie, DG; Knecht, E; Moreno, D; Sanz, P; Towler, MC | 1 |
| Arnott, D; Bakalarski, CE; Bustos, D; Deshayes, K; Dixit, VM; Dynek, JN; Fedorova, AV; Izrael-Tomasevic, A; Kelley, RF; Kirkpatrick, DS; Matsumoto, ML; Phu, L; Vucic, D | 1 |
| Beli, P; Choudhary, C; Cox, J; Mann, M; Nielsen, ML; Wagner, SA; Weinert, BT | 1 |
| Kim, DY; Scalf, M; Smith, LM; Vierstra, RD | 1 |
| Barter, MJ; Charlton, SH; Coulombe, J; Destrument, AP; Gibson, B; Gray, DA; Hui, W; Radwan, M; Rowan, AD; Wilkinson, DJ; Young, DA | 1 |
| Fitzpatrick, T; Hao, R; Nanduri, P; Yao, TP | 1 |
| Bhattacharjee, H; Mandal, G; Mandal, S; Mukhopadhyay, R; Sharma, M | 1 |
| Fadool, DA; Iyer, SR; Schwartz, AB; Vélez, P; Warrington, A | 1 |
| McCarthy, C; Ortega-Atienza, S; Rubis, B; Zhitkovich, A | 1 |
| Ge, Y; Rana, ASJB; Strieter, ER | 1 |
| Calera, MR; Macías-Silva, M; Méndez-Hernández, LE; Robledo-Rivera, AY; Sánchez-Olea, R | 1 |
| Kelleher, NL; McClure, RA; Mullowney, MW; Robey, MT; Thomson, RJ | 1 |
| Cao, L; Qian, H; Sun, Y; Wu, S; Zhang, N; Zhang, Y | 1 |
| Dittmar, G; Longworth, J; Mendes, ML | 1 |
2 review(s) available for lysine and leupeptins
| Article | Year |
|---|---|
"Defective" receptors in steroid-resistant conditions may be proteolytic artifacts.
Topics: Animals; Breast; Breast Neoplasms; Centrifugation, Density Gradient; Cytosol; Drug Resistance; Endometrium; Endopeptidases; Female; Humans; Kidney; Leukemia; Leupeptins; Liver; Lysine; Macromolecular Substances; Male; Molybdenum; Osmolar Concentration; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Substrate Specificity; Ultracentrifugation; Uterine Neoplasms | 1986 |
Natural products from thioester reductase containing biosynthetic pathways.
Topics: Alkaloids; Azabicyclo Compounds; Benzodiazepinones; Biological Products; Biosynthetic Pathways; Cyclization; Depsipeptides; Dipeptides; Indoles; Lactams; Leupeptins; Lysine; Multigene Family; Peptide Synthases; Polyketide Synthases; Protein Domains | 2018 |
27 other study(ies) available for lysine and leupeptins
| Article | Year |
|---|---|
Activation of human Glu-plasminogen to Glu-plasmin by urokinase in presence of plasmin inhibitors. Streptomyces leupeptin and human plasma alpha1-antitrypsin and antithrombin III (plus heparin).
Topics: alpha 1-Antitrypsin; Antithrombins; Fibrinolysin; Glutamine; Heparin; Humans; Leupeptins; Lysine; Oligopeptides; Plasminogen; Plasminogen Activators; Streptomyces; Urokinase-Type Plasminogen Activator | 1977 |
The effects of cytotropic compounds on the resialylation of human asialotransferrin type 3 in the rat.
Topics: Alkaloids; Animals; Asialoglycoproteins; Chloroquine; Colchicine; Female; Humans; Leupeptins; Liver; Lysine; Male; Microtubules; Paclitaxel; Protein Biosynthesis; Rats; Starvation; Transferrin; Vinblastine | 1985 |
Cytochemical demonstrations of protease in human peripheral blood cells by use of new alpha-naphthyl ester substrates.
Topics: Chymotrypsin; Histocytochemistry; Humans; Iodoacetates; Iodoacetic Acid; Isoflurophate; Leukocytes; Leupeptins; Lysine; Male; Naphthols; Neutrophils; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Substrate Specificity; Tyrosine | 1983 |
T cell recognition of major histocompatibility complex class II complexes with invariant chain processing intermediates.
Topics: Alleles; Amino Acid Sequence; Animals; Antigen Presentation; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Binding Sites; Epitopes; Glycine; Histocompatibility Antigens Class II; Humans; Hybrid Cells; Leupeptins; Lysine; Macromolecular Substances; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Sequence Data; Peptide Fragments; Protein Binding; Protein Conformation; Rats; Receptors, Antigen, T-Cell; Sequence Alignment; Structure-Activity Relationship; T-Lymphocytes; Transfection | 1995 |
Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line; Conserved Sequence; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; Genes, Tumor Suppressor; Humans; Leupeptins; Lysine; Molecular Sequence Data; Multienzyme Complexes; Nuclear Proteins; Proteasome Endopeptidase Complex; Protein Binding; Protein Processing, Post-Translational; Protein Transport; SUMO-1 Protein; Transfection; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Two-Hybrid System Techniques; Ubiquitins | 2000 |
Coaggregation of Porphyromonas gingivalis and Prevotella intermedia.
Topics: Adhesins, Bacterial; alpha-Amylases; Arginine; Bacterial Adhesion; Bacterial Proteins; Cysteine Endopeptidases; Endopeptidase K; Fimbriae Proteins; Gingipain Cysteine Endopeptidases; Hemagglutinins; Hot Temperature; Humans; Lectins; Leupeptins; Lysine; Mutation; Plant Proteins; Porphyromonas gingivalis; Prevotella intermedia; Tosyllysine Chloromethyl Ketone; Trypsin Inhibitors | 2001 |
Involvement of proteases in the action of IFN-gamma on WISH cells.
Topics: Amnion; Cell Division; Cell Line; Cell Membrane; DNA Replication; Humans; Interferon-gamma; Leupeptins; Lysine; Pepstatins; Phenylalanine; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine Endopeptidases; Serine Proteinase Inhibitors; Subcellular Fractions; Thiorphan; Tosyllysine Chloromethyl Ketone; Trypsin Inhibitor, Bowman-Birk Soybean | 2002 |
Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A.
Topics: Acetylcysteine; Apoptosis; Caspase 3; Caspases; Cysteine Endopeptidases; Diamines; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Eukaryotic Translation Initiation Factor 5A; Gene Expression Profiling; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Megakaryoblastic, Acute; Leupeptins; Lysine; Multienzyme Complexes; Oligodeoxyribonucleotides, Antisense; Peptide Initiation Factors; Peptide Mapping; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteomics; RNA-Binding Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Tumor Cells, Cultured; Ubiquitin | 2003 |
Control of peroxisome proliferator-activated receptor gamma2 stability and activity by SUMOylation.
Topics: Adipose Tissue; Animals; Blotting, Western; Cysteine Proteinase Inhibitors; Gene Expression Regulation; HeLa Cells; Humans; Hypoglycemic Agents; Leupeptins; Lysine; Mice; Mutagenesis, Site-Directed; NIH 3T3 Cells; Receptors, Cytoplasmic and Nuclear; SUMO-1 Protein; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Transfection | 2004 |
Plasminogen/plasmin regulates c-fos and egr-1 expression via the MEK/ERK pathway.
Topics: Animals; Binding Sites; Blotting, Northern; Blotting, Western; Cell Line; Cholera Toxin; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Enzyme Activation; Fibrinolysin; Flavonoids; Genes, Dominant; Humans; Immediate-Early Proteins; Leupeptins; Lysine; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Plasminogen; Protein Binding; Proto-Oncogene Proteins c-fos; RNA; RNA, Messenger; Serine Endopeptidases; Signal Transduction; Time Factors; Transcription Factors | 2005 |
Deubiquitination by proteasome is coordinated with substrate translocation for proteolysis in vivo.
Topics: Amino Acid Substitution; Arginine; Blotting, Western; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Gene Expression; HeLa Cells; Humans; Leupeptins; Lysine; Mutation; Oligopeptides; Peptide Fragments; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Subunits; Proteins; Recombinant Fusion Proteins; Trans-Activators; Transfection; Ubiquitin | 2005 |
Defective protein folding and intracellular retention of thyroglobulin-R19K mutant as a cause of human congenital goiter.
Topics: Alkaloids; Amino Acid Substitution; Animals; Arginine; Biological Transport; Blotting, Western; Calnexin; Chlorocebus aethiops; COS Cells; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Goiter; Golgi Apparatus; Heat-Shock Proteins; Humans; Immunoprecipitation; Leupeptins; Lysine; Mice; Molecular Chaperones; Mutation; Protein Binding; Protein Disulfide-Isomerases; Protein Folding; Signal Transduction; Thyroglobulin | 2008 |
A single mutation at lysine 241 alters expression and trafficking of the D2 dopamine receptor.
Topics: Animals; Cell Line; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Ethylmaleimide; Humans; Leupeptins; Lysine; Mutagenesis, Site-Directed; Mutation; Proteasome Endopeptidase Complex; Protein Transport; Rats; Receptors, Dopamine D2; Signal Transduction; Transfection; Ubiquitin; Ubiquitination | 2008 |
Investigation of a role for lysine residues in non-structural proteins 2 and 2/3 of the hepatitis C virus for their degradation and virus assembly.
Topics: Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA, Viral; Gene Expression Regulation, Viral; Genome, Viral; Genotype; Hepacivirus; Humans; Leupeptins; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Viral Nonstructural Proteins; Virus Assembly | 2009 |
The laforin-malin complex, involved in Lafora disease, promotes the incorporation of K63-linked ubiquitin chains into AMP-activated protein kinase beta subunits.
Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cell Line; Humans; Lafora Disease; Leupeptins; Lysine; Mice; Multiprotein Complexes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Multimerization; Protein Processing, Post-Translational; Protein Stability; Protein Transport; Protein Tyrosine Phosphatases, Non-Receptor; Substrate Specificity; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2010 |
Improved quantitative mass spectrometry methods for characterizing complex ubiquitin signals.
Topics: Amino Acid Sequence; HEK293 Cells; Humans; Immunoprecipitation; Jurkat Cells; Leupeptins; Lysine; Methionine; Molecular Sequence Data; Mutant Proteins; Oxidation-Reduction; Peptide Fragments; Proteasome Inhibitors; Tandem Mass Spectrometry; Ubiquitin; Ubiquitinated Proteins; Ubiquitination | 2011 |
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
Topics: Acetylation; Genome, Human; HEK293 Cells; Humans; Leupeptins; Lysine; Mass Spectrometry; Peptides; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Proteome; Signal Transduction; Ubiquitin; Ubiquitination | 2011 |
Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cysteine Proteinase Inhibitors; Immunoblotting; Leupeptins; Lysine; Mass Spectrometry; Plants, Genetically Modified; Proteasome Endopeptidase Complex; Proteome; Proteomics; Ubiquitin; Ubiquitinated Proteins; Ubiquitination | 2013 |
Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination.
Topics: Animals; Cysteine Proteinase Inhibitors; Disease Models, Animal; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Leupeptins; Lysine; Matrix Metalloproteinase 13; Mice, Inbred C57BL; Mice, Transgenic; Osteoarthritis; Proteasome Endopeptidase Complex; Signal Transduction; Ubiquitination; Zinc Fingers | 2015 |
Chaperone-mediated 26S proteasome remodeling facilitates free K63 ubiquitin chain production and aggresome clearance.
Topics: Benzoquinones; Blotting, Western; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Histone Deacetylase 6; Histone Deacetylases; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leupeptins; Lysine; Microscopy, Confocal; Proteasome Endopeptidase Complex; Protein Aggregates; RNA Interference; Trans-Activators; Ubiquitin; Ubiquitination | 2015 |
Functional role of lysine 12 in Leishmania major AQP1.
Topics: Amino Acid Substitution; Aquaglyceroporins; DNA Mutational Analysis; Leishmania major; Leupeptins; Lysine; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Protein Stability; Protein Transport; Proteolysis | 2015 |
Ubiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targeting.
Topics: Animals; Antibodies; Cell Line, Transformed; Cysteine; Cysteine Proteinase Inhibitors; Down-Regulation; Electric Stimulation; Endosomal Sorting Complexes Required for Transport; Gene Expression Regulation; GRB10 Adaptor Protein; HEK293 Cells; Humans; Kv1.3 Potassium Channel; Leupeptins; Lysine; Membrane Potentials; Models, Biological; Mutation; Nedd4 Ubiquitin Protein Ligases; Patch-Clamp Techniques; RNA-Binding Protein FUS; Ubiquitin-Protein Ligases; Ubiquitination | 2016 |
Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins.
Topics: Cell Line; DNA-Binding Proteins; Endoplasmic Reticulum; Formaldehyde; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Leupeptins; Lysine; Phosphorylation; Polyubiquitin; Proteasome Endopeptidase Complex; Transcription Factors; Ubiquitination | 2016 |
Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry (UbiChEM-MS) Reveals Cell-Cycle Dependent Formation of Lys11/Lys48 Branched Ubiquitin Chains.
Topics: Amino Acid Sequence; Aminopyridines; Deubiquitinating Enzymes; HEK293 Cells; Humans; Leupeptins; Lysine; Mass Spectrometry; Mitosis; Nocodazole; Polyubiquitin; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Thiocyanates; Ubiquitin | 2017 |
Gpn3 is polyubiquitinated on lysine 216 and degraded by the proteasome in the cell nucleus in a Gpn1-inhibitable manner.
Topics: Cell Line; Cell Nucleus; GTP Phosphohydrolases; GTP-Binding Proteins; Half-Life; HEK293 Cells; Humans; Leupeptins; Lysine; Mutation; Proteasome Endopeptidase Complex; Ubiquitination | 2017 |
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
Topics: Animals; Cardiomegaly; Fibrosis; Heart Failure; Humans; Isoproterenol; Leupeptins; Lysine; Male; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Myocardium; Poly ADP Ribosylation; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Protein Binding; Proteolysis; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination; Ventricular Remodeling | 2020 |
Ubiquitin Chain Analysis by Parallel Reaction Monitoring.
Topics: Alkylation; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatography, Liquid; Humans; Leupeptins; Lysine; Mass Spectrometry; Mice; Peptides; Proteome; Reference Standards; Software; Ubiquitin | 2020 |