lysine has been researched along with guanosine triphosphate in 69 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 26 (37.68) | 18.7374 |
1990's | 17 (24.64) | 18.2507 |
2000's | 13 (18.84) | 29.6817 |
2010's | 12 (17.39) | 24.3611 |
2020's | 1 (1.45) | 2.80 |
Authors | Studies |
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Cosson, MP; Gros, C; Pantaloni, D; Talbot, JC | 1 |
Hague, DR; Kofoid, EC; Menninger, JR | 1 |
Cantor, CR; Johnson, AE; Miller, DL | 1 |
Ghosh, HP; Sen, GC | 1 |
Cook, GH; Wolff, J | 1 |
Akbarov, AKh; Kochetkov, SN; Luchin, SV; Memelova, LV; Rechinsky, VO; Tunitskaya, VL | 1 |
Almo, SC; Kabsch, W; Lentfer, A; Pai, EF; Petratos, K; Petsko, GA; Rapp, G; Schlichting, I; Wilson, K; Wittinghofer, A | 1 |
Anborgh, PH; Cool, RH; Gümüşel, F; Parmeggiani, A; Weijland, A | 1 |
Hwang, YW; Miller, DL; Sanchez, A | 1 |
Johnson, AE; Krieg, UC; Walter, P | 1 |
Bosch, L; Johanns, ES; Kraal, B; Persoon, NL; Sinjorgo, KM; Van Noort, JM | 1 |
Fukui, T; Hattori, S; Hoshino, M; Kawakita, M; Ohmi, N; Tagaya, M | 1 |
Frieden, C; Goldin, BR | 2 |
Bradshaw, RA; Coffee, CJ; Frieden, C; Goldin, BR | 1 |
Hucho, F; Markau, U; Sund, H | 1 |
Holbrook, JJ; Wallis, RB | 1 |
Birnbaumer, L; Yang, PC | 1 |
Brot, N; Davis, RC; Pestka, S; Redfield, B; Weissbach, H; Yamasaki, E | 1 |
Amons, R; Möller, W | 1 |
Marcus, A; Seal, SN | 1 |
Brot, N; Pestka, S | 1 |
Lin, YC; Okuyama, A; Tanaka, N | 1 |
Kassab, R; Pradel, LA; Roustan, C; Van Thoai, N | 1 |
Brattin, WJ; Landon, M; Langley, TJ; Melamed, MD; Piszkiewicz, D; Smith, EL | 1 |
Conde, P; Pintor-Toro, JA; Sanchez-Madrid, F; Vidal, MA | 1 |
Colman, RF; Jacobson, MA | 1 |
Antonsson, B; Leberman, R | 1 |
Sprinzl, M; Wagner, T | 1 |
Clark, BF; Kjeldgaard, M; Nissen, P; Nyborg, J; Polekhina, G; Reshetnikova, L; Thirup, S | 1 |
Lee, YH; Lin, K; Okar, D; Pilkis, SJ | 1 |
Cong, P; Shuman, S | 1 |
Johnson, GL; Russell, M | 1 |
Cerione, RA; Leonard, DA; Manor, D; Nomanbhoy, TK | 1 |
Rikkonen, M | 1 |
Birckbichler, PJ; Itoh, Y; Ohashi, H; Takeuchi, Y | 1 |
Baker, S; Ehrenfeld, E; Richards, OC | 1 |
Ehrenfeld, E; Richards, OC | 1 |
Clark, BF; Knudsen, CR; Nautrup Pedersen, G; Rattenborg, T | 1 |
Brunner, J; Helms, JB; Wieland, FT; Zhao, L | 1 |
Gilman, AG; Mukhopadhyay, S; Posner, BA; Ross, EM; Tesmer, JJ | 1 |
Bhattacharya, S; Gabriel, K; Jou, YY; McClain, WH; Schneider, J | 1 |
Futatsugi, N; Hata, M; Hoshino, T; Tsuda, M | 1 |
Gudkov, AT; Liljas, A; Martemyanov, KA; Yarunin, AS | 1 |
Futatsugi, N; Tsuda, M | 1 |
Bearne, SL; Hewitt, KA; Iyengar, A; Lunn, F; Simard, D | 1 |
Bennett, VJ; Kim, P; Shafer, AM; Voss, JC | 1 |
Downs, MA; Hargrave, PA; Kisselev, OG; McDowell, JH | 1 |
Chen, JY; Hsu, TY; Wu, CC | 1 |
Gudkov, AT; Hansson, S; Liljas, A; Logan, DT; Singh, R | 1 |
Boja, ES; Che, MM; Fales, HM; Gruschus, J; Jaffe, H; Randazzo, PA; Schuck, P; Stauffer, S; Yoon, HY | 1 |
Chan, SH; Dong, HJ; Guan, WJ; Li, YQ; Shen, XL; Tao, SM; Wang, CX | 1 |
Balasundaram, D; Kumari, G; Mahalingam, S; Rao, MR; Sankaranarayanan, R | 1 |
Alifano, P; Bucci, C; De Luca, A; Progida, C; Spinosa, MR | 1 |
Katanaev, VL; Kopein, D | 1 |
Bar-Sagi, D; Boykevisch, S; Ford, B; Herrmann, C; Kunzelmann, S; Nassar, N; Zhao, C | 1 |
Anastasiou, D; Asara, JM; Cantley, LC; Carracedo, A; Haviv, S; Kahoud, ER; Locasale, JW; Pandolfi, PP; Sasaki, AT; Takeuchi, K | 1 |
Herrmann, C; Kunzelmann, S; Wehner, M | 1 |
Bar-Sagi, D; Haigis, KM; Haigis, MC; Kim, ET; Laurent, G; Liot, C; Nickerson, S; Philips, MR; Shan, Y; Shaw, DE; Spang, R; Yang, MH | 1 |
Chirifu, M; Hashikawa, C; Ikemizu, S; Inazato, M; Koga, Y; Kuniyasu, A; Michi, A; Nakabeppu, Y; Nakamura, T; Toma, S; Yamagata, Y; Yamashita, T | 1 |
Konevega, AL; Mittelstaet, J; Rodnina, MV | 1 |
Brodbelt, JS; Browning, KS; Mayberry, LK; Murphy, PA; O'Brien, JP | 1 |
Anastasiou, D; Asara, JM; Charest, PG; Firtel, RA; Kahoud, ER; Kuroda, T; Lee, S; Majd, N; Sasaki, AT; Sasaki, M; Sumita, K; Takahashi, H; Takeda, K; Takeuchi, K; Yoshino, H | 1 |
Jeganathan, A; Ortega, J; Razi, A; Thurlow, B | 1 |
Cai, Z; Chan, CH; Chou, PC; Gao, Y; Gong, Z; Han, F; Ho, YS; Huang, CY; Jin, G; Lee, SW; Lin, HK; Rezaeian, AH; Sarbassov, dos D; Tsai, CH; Tsai, FJ; Tu, SH; Wang, CY; Wu, CH; Yao, JC; Zhang, X | 1 |
Baldus, L; Brenig, J; de Boor, S; Knyphausen, P; Krüger, M; Kuhlmann, N; Lammers, M; Nolte, H; Scislowski, L; Wroblowski, S | 1 |
Aileni, VK; Falnes, PØ; Ho, AYY; Jakobsson, ME; Leidel, SA; Malecki, J; Moen, A; Nilges, BS; Schwarz, J; Sørensen, V | 1 |
Inoshita, M; Mima, J | 1 |
Casaulta, C; Gao, J; Latzin, P; Oberson, K; Peng, S; Simon, HU; Stojkov, D; Yousefi, S | 1 |
69 other study(ies) available for lysine and guanosine triphosphate
Article | Year |
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Physicochemical evidence for the existence of two pyridoxal 5'-phosphate binding sites on glutamate dehydrogenase and characterization of their functional role.
Topics: Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Guanosine Triphosphate; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Ligands; Liver; Lysine; Molecular Weight; NADP; Protein Conformation; Pyridoxal Phosphate | 1977 |
Studies on termination of protein synthesis in wheat germ.
Topics: Cell-Free System; Codon; Cycloheximide; Fusidic Acid; Guanosine Triphosphate; Lysine; Methanol; Oligopeptides; Peptide Chain Termination, Translational; Phenylalanine; Poly A-U; Poly U; Protein Biosynthesis; Puromycin; Solubility; Sparsomycin; Triticum | 1979 |
Functional covalent complex between elongation factor Tu and an analog of lysyl-tRNA.
Topics: Affinity Labels; Alkylation; Binding Sites; Escherichia coli; Guanosine Triphosphate; Lysine; Magnesium; Peptide Elongation Factors; Ribosomes; RNA, Transfer, Amino Acyl | 1978 |
Role of modified nucleosides in tRNA: effect of modification of the 2-thiouridine derivative located at the 5'-end of the anticodon of yeast transfer RNA Lys2.
Topics: Anticodon; Chromatography, High Pressure Liquid; Cyanogen Bromide; Guanosine Triphosphate; Kinetics; Lysine; Peptide Chain Elongation, Translational; Peptide Elongation Factors; Protein Biosynthesis; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Thiouridine | 1976 |
Charge effects in the activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Enzyme Activation; Fluorides; Guanosine Triphosphate; Kinetics; Lysine; Magnesium; Muramidase; Peptides; Potassium Chloride; Prostaglandins E; Ribonucleases; Spermidine; Spermine; Thyroid Gland; Thyrotropin | 1975 |
Inactivation of bacteriophage T7 DNA-dependent RNA polymerase by 5'-p-fluorosulfonylbenzoyladenosine. Identification of the modification site and the effect of the modification on enzyme action.
Topics: Adenosine; Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; DNA-Directed RNA Polymerases; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; Lysine; Molecular Sequence Data; Peptide Fragments; RNA; T-Phages; Transcription, Genetic; Trypsin | 1990 |
Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis.
Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallization; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Lysine; Magnesium; Models, Molecular; Molecular Structure; Phosphates; Photolysis; Protein Conformation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); X-Ray Diffraction | 1990 |
Mutagenesis of the NH2-terminal domain of elongation factor Tu.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Computer Graphics; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Leucine; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Conformation; Thermodynamics; Urea; Valine | 1990 |
Mutagenesis of bacterial elongation factor Tu at lysine 136. A conserved amino acid in GTP regulatory proteins.
Topics: Amino Acid Sequence; Chromatography, Gel; Escherichia coli; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Lysine; Molecular Sequence Data; Mutation; Peptide Elongation Factor Tu; Peptide Elongation Factors; Plasmids; Protein Conformation; RNA, Transfer, Phe; Structure-Activity Relationship; Transformation, Bacterial | 1989 |
Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle.
Topics: Affinity Labels; Guanosine Triphosphate; Light; Lysine; Peptide Elongation Factor Tu; Prolactin; Protein Biosynthesis; Protein Precursors; Protein Sorting Signals; RNA, Transfer, Amino Acyl | 1986 |
Methylation in vivo of elongation factor EF-Tu at lysine-56 decreases the rate of tRNA-dependent GTP hydrolysis.
Topics: Escherichia coli; Ethylmaleimide; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Lysine; Methylation; Peptide Elongation Factor Tu; RNA, Transfer | 1986 |
Affinity labeling of ras oncogene product p21 with guanosine diphospho- and triphosphopyridoxals.
Topics: Affinity Labels; Amino Acid Sequence; Amino Acids; Binding, Competitive; Escherichia coli; Genes, ras; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Lysine; Membrane Proteins; Molecular Sequence Data; Peptide Mapping; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Trypsin | 1988 |
The effect of pyridoxal phosphate modification on the catalytic and regulatory properties of bovine liver glutamate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Catalysis; Cattle; Enzyme Activation; Glutamate Dehydrogenase; Guanosine Triphosphate; Kinetics; Liver; Lysine; Macromolecular Substances; NAD; Nitrobenzenes; Peptides; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Sulfonic Acids | 1972 |
Identification of the sites of modification of bovine liver glutamate dehydrogenase reacted with trinitrobenzenesulfonate.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Gel; Chromatography, Ion Exchange; Dansyl Compounds; Glutamate Dehydrogenase; Guanosine Triphosphate; Hydantoins; Iodoacetates; Kinetics; Liver; Lysine; NAD; Nitrobenzenes; Peptides; Spectrophotometry; Sulfhydryl Compounds; Sulfides; Sulfonic Acids; Trypsin | 1971 |
Studies of glutamate dehydrogenase. Characterization of histidine residues involved in the activity and association. Photoactivated labelling with pyridoxal 5'-phosphate.
Topics: Adenosine Diphosphate; Amino Acids; Binding Sites; Carbonates; Diphosphates; Enzyme Activation; Glutamate Dehydrogenase; Guanosine Triphosphate; Histidine; Imidazoles; Light; Lysine; NAD; Photochemistry; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry, Ultraviolet; Tritium | 1973 |
The effect of modifying lysine-126 on the physical, catalytic and regulatory properties of bovine liver glutamate dehydrogenase.
Topics: Adenosine Diphosphate; Amides; Animals; Binding Sites; Carbon Isotopes; Cattle; Chromatography, Gel; Glutamate Dehydrogenase; Guanosine Triphosphate; Hydrogen-Ion Concentration; Iodoacetates; Ketoglutaric Acids; Kinetics; Liver; Lysine; NAD; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Salicylates; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sulfites; Time Factors; Ultracentrifugation | 1973 |
Studies on receptor-mediated activation of adenylyl cyclases. I. Preparation and description of general properties of an adenylyl cyclase system in beef renal medullary membranes sensitive to neurohypophyseal hormones.
Topics: Adenylyl Cyclases; Animals; Arginine; Cattle; Cell Membrane; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyclic AMP; Enzyme Activation; Guanosine Triphosphate; Kidney; Kidney Medulla; Kinetics; Lysine; Microscopy, Phase-Contrast; Oxytocin; Phosphorus Radioisotopes; Receptors, Cell Surface; Subcellular Fractions; Time Factors; Tritium; Vasopressins | 1974 |
Effect of trinitrophenylation of specific lysyl residues on the catalytic, regulatory, and molecular properties of bovine liver glutamate dehydrogenase.
Topics: Adenosine Diphosphate; Allosteric Regulation; Animals; Catalysis; Cattle; Chromatography, Gel; Enzyme Activation; Glutamate Dehydrogenase; Guanosine Triphosphate; Ketoglutaric Acids; Kinetics; Liver; Lysine; Macromolecular Substances; NAD; NADP; Nitrobenzenes; Rats; Spectrophotometry; Sulfonic Acids; Ultracentrifugation | 1971 |
Studies on the ribosomal sites involved in factors Tu and G-dependent reactions.
Topics: Ammonium Chloride; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Carbon Isotopes; Electrophoresis, Disc; Escherichia coli; Ethanol; Guanosine Triphosphate; Hot Temperature; Kinetics; Lysine; Peptide Chain Elongation, Translational; Peptides; Phenylalanine; Phosphorus Isotopes; Polynucleotides; Ribosomes; RNA, Transfer; Tritium; Uracil Nucleotides | 1972 |
Reductive-methylation studies on L7 and L12 ribosomal proteins.
Topics: Acetylation; Acylation; Amino Acid Sequence; Autoanalysis; Bacterial Proteins; Binding Sites; Borohydrides; Carbon Radioisotopes; Centrifugation, Zonal; Chromatography; Electrophoresis; Escherichia coli; Formaldehyde; Guanosine Triphosphate; Isoelectric Focusing; Lysine; Macromolecular Substances; Methylation; Muramidase; Nucleotidases; Peptide Elongation Factors; Peptide Fragments; Ribosomes; Serine; Trypsin | 1974 |
Translation of the initial codons of satellite tobacco necrosis virus ribonucleic acid in a cell-free system from wheat embryo.
Topics: Adenosine Triphosphate; Alanine; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Chlortetracycline; Chromatography, Paper; Dipeptides; Guanosine Triphosphate; Lysine; Magnesium; Methionine; Peptide Chain Initiation, Translational; Peptide Elongation Factors; Peptide Initiation Factors; Plant Cells; Plants; Protein Biosynthesis; Ribosomes; RNA, Messenger; RNA, Transfer; RNA, Viral; Satellite Viruses; Transfer RNA Aminoacylation; Triticum | 1973 |
Studies on the formation of transfer ribonucleic acid-ribosome complexes. IV. Effect of antibiotics on steps of bacterial protein synthesis: some new ribosomal inhibitors of translocation.
Topics: Adenine Nucleotides; Anti-Bacterial Agents; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; Cytosine Nucleotides; Escherichia coli; Guanine Nucleotides; Guanosine Triphosphate; Leucomycins; Lincomycin; Lysine; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptides; Phenylalanine; Phosphorus Isotopes; Polynucleotides; Puromycin; Ribosomes; RNA, Transfer; Tritium | 1971 |
Studies on translocation of F-MET-tRNA and peptidyl-tRNA with antibiotics.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Carbon Isotopes; Escherichia coli; Formates; Fusidic Acid; Guanine Nucleotides; Guanosine Triphosphate; Lactones; Leucine; Lysine; Methionine; Models, Biological; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptides; Polymers; Polynucleotides; Puromycin; Ribosomes; RNA, Messenger; RNA, Transfer; Tritium | 1971 |
Studies on the partial exchange and overall reactions catalyzed by native and modified arginine kinase from Homarus vulgaris muscle.
Topics: Adenine Nucleotides; Alkylation; Animals; Annelida; Arginine; Binding Sites; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Creatine Kinase; Cysteine; Dansyl Compounds; Guanosine Triphosphate; Histidine; Kinetics; L-Lactate Dehydrogenase; Lysine; Muscles; Nephropidae; Phosphotransferases; Protein Binding; Pyruvate Kinase; Rabbits | 1971 |
Bovine liver glutamate dehydrogenase: tentative amino acid sequence; identification of a reactive lysine; nitration of a specific tyrosine and loss of allosteric inhibition by guanosine triphosphate.
Topics: Amino Acid Sequence; Animals; Cattle; Chemical Phenomena; Chemistry; Glutamate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanosine Triphosphate; Liver; Lysine; Methods; Molecular Weight; Nitrates; Stereoisomerism; Tyrosine | 1970 |
Studies on the modification of Escherichia coli ribosomal protein L7/L12 by succinic anhydride.
Topics: Epitopes; Escherichia coli; Guanosine Triphosphate; Immunodiffusion; Lysine; Peptide Biosynthesis; Peptide Elongation Factor G; Peptide Elongation Factors; Peptides; Ribosomal Proteins; Succinates; Succinic Anhydrides | 1982 |
Resonance energy transfer between the adenosine 5'-diphosphate site of glutamate dehydrogenase and a guanosine 5'-triphosphate site containing a tyrosine labeled with 5'-[p-(fluorosulfonyl)benzoyl]-1,N6-ethenoadenosine.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Animals; Cattle; Energy Transfer; Glutamate Dehydrogenase; Guanosine Triphosphate; Kinetics; Liver; Lysine; Tyrosine | 1983 |
Modification of amino groups in EF-Tu.GTP and the ternary complex EF-Tu.GTP.valyl-tRNAVal.
Topics: Amino Acids; Binding Sites; Chromatography, High Pressure Liquid; Guanosine Triphosphate; Imidoesters; Lysine; Peptide Elongation Factor Tu; Peptide Elongation Factors; Peptide Fragments; RNA, Transfer, Amino Acyl; Trypsin | 1984 |
The complex formation between Escherichia coli aminoacyl-tRNA, elongation factor Tu and GTP. The effect of the side-chain of the amino acid linked to tRNA.
Topics: Amino Acyl-tRNA Synthetases; Escherichia coli; Guanosine Triphosphate; Lysine; Peptide Elongation Factors; Phenylalanine; Poly A; Poly U; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Structure-Activity Relationship; Substrate Specificity | 1980 |
Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog.
Topics: Amino Acid Sequence; Anticodon; Base Sequence; Binding Sites; Crystallography, X-Ray; Guanosine Diphosphate; Guanosine Triphosphate; Histidine; Lysine; Models, Molecular; Molecular Mimicry; Molecular Sequence Data; Nucleic Acid Conformation; Peptide Elongation Factor G; Peptide Elongation Factor Tu; Peptide Elongation Factors; Peptide Initiation Factors; Peptide Termination Factors; Prokaryotic Initiation Factor-2; Protein Biosynthesis; Protein Conformation; Protein Structure, Secondary; Ribosomes; RNA, Transfer, Amino Acyl; Thermus | 1995 |
Mechanism of modulation of rat liver fructose-2,6-bisphosphatase by nucleoside triphosphates.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Animals; Arginine; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; Kinetics; Liver; Lysine; Molecular Weight; Mutagenesis, Site-Directed; Phosphofructokinase-2; Phosphoric Monoester Hydrolases; Point Mutation; Rats; Recombinant Proteins; Sequence Deletion | 1994 |
Covalent catalysis in nucleotidyl transfer. A KTDG motif essential for enzyme-GMP complex formation by mRNA capping enzyme is conserved at the active sites of RNA and DNA ligases.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cloning, Molecular; Conserved Sequence; DNA Ligases; Electrophoresis, Polyacrylamide Gel; Guanosine Monophosphate; Guanosine Triphosphate; Lysine; Methyltransferases; Molecular Sequence Data; Multienzyme Complexes; Mutation; Nucleotides; Nucleotidyltransferases; Phosphoric Monoester Hydrolases; RNA Ligase (ATP); Viral Proteins | 1993 |
G protein amino-terminal alpha i2/alpha s chimeras reveal amino acids important in regulating alpha s activity.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cyclic AMP; Enzyme Activation; Glutamine; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Recombinant Fusion Proteins; Sequence Alignment | 1993 |
Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using extrinsic reporter group fluorescence.
Topics: Animals; Binding Sites; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Energy Transfer; Fluorescent Dyes; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Humans; In Vitro Techniques; Lysine; Models, Molecular; Oxadiazoles; Protein Conformation; Proteins; ras GTPase-Activating Proteins; ras Guanine Nucleotide Exchange Factors; ras Proteins; Recombinant Fusion Proteins | 1996 |
Functional significance of the nuclear-targeting and NTP-binding motifs of Semliki Forest virus nonstructural protein nsP2.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Arginine; Base Sequence; Binding Sites; Cell Line; Cell Nucleus; Cricetinae; Cytoplasm; DNA; Female; Guanosine Triphosphate; Lysine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Protein Biosynthesis; Semliki forest virus; Viral Nonstructural Proteins; Virus Replication | 1996 |
Purification and characterization of rat brain transglutaminase.
Topics: Affinity Labels; Animals; Binding Sites; Blotting, Western; Brain; Cations; Chromatography, Affinity; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Erythrocytes; Glutamine; Guanosine Triphosphate; Guinea Pigs; Humans; Kinetics; Liver; Lysine; Male; Molecular Weight; Rats; Rats, Sprague-Dawley; Transglutaminases | 1995 |
Mutation of lysine residues in the nucleotide binding segments of the poliovirus RNA-dependent RNA polymerase.
Topics: Chromatography, Agarose; Guanosine Triphosphate; HeLa Cells; Humans; Lysine; Mutagenesis; Poliovirus; RNA-Dependent RNA Polymerase; Transfection | 1996 |
One of two NTP binding sites in poliovirus RNA polymerase required for RNA replication.
Topics: Arginine; Binding Sites; Borohydrides; Cross-Linking Reagents; Cyanogen Bromide; Guanosine Triphosphate; Leucine; Lysine; Nucleotides; Peptide Fragments; Poliovirus; RNA-Dependent RNA Polymerase; RNA, Viral | 1997 |
Contribution of Arg288 of Escherichia coli elongation factor Tu to translational functionality.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Asparagine; Binding Sites; Conserved Sequence; Escherichia coli; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen Bonding; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Conformation; Recombinant Proteins; Ribosomes; RNA, Transfer, Phe; Thermus | 1997 |
GTP-dependent binding of ADP-ribosylation factor to coatomer in close proximity to the binding site for dilysine retrieval motifs and p23.
Topics: ADP-Ribosylation Factors; Animals; Binding Sites; Carrier Proteins; Cattle; CHO Cells; Coatomer Protein; Cricetinae; Cross-Linking Reagents; Crystallography, X-Ray; Dimerization; Golgi Apparatus; GTP-Binding Proteins; Guanosine Triphosphate; Lysine; Macromolecular Substances; Membrane Proteins; Microtubule-Associated Proteins; Molecular Weight; Photochemistry; Protein Conformation; Protein Structure, Secondary; Rabbits | 1999 |
Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.
Topics: Animals; Asparagine; Binding, Competitive; Conserved Sequence; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Proline; Protein Binding; Proteins; Receptors, Cell Surface; RGS Proteins; Serine | 1999 |
The reliability of in vivo structure-function analysis of tRNA aminoacylation.
Topics: Acylation; Alanine-tRNA Ligase; Base Sequence; Blotting, Northern; Escherichia coli; Genes, Suppressor; Guanosine Triphosphate; Lysine; Mutation; Peptide Elongation Factor Tu; Protein Binding; Reproducibility of Results; RNA, Bacterial; RNA, Transfer, Ala; RNA, Transfer, Amino Acyl; Structure-Activity Relationship; Suppression, Genetic | 1999 |
Ab initio study of the role of lysine 16 for the molecular switching mechanism of Ras protein p21.
Topics: Animals; Binding Sites; Biophysical Phenomena; Biophysics; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; In Vitro Techniques; Lysine; Models, Molecular; Protein Conformation; Proto-Oncogene Proteins p21(ras); Thermodynamics; Water | 1999 |
Mutations in the G-domain of elongation factor G from Thermus thermophilus affect both its interaction with GTP and fusidic acid.
Topics: Alanine; Aspartic Acid; Binding Sites; Cell-Free System; Fusidic Acid; Genetic Variation; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor G; Poly U; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Proteins; Thermus thermophilus; Threonine | 2001 |
Molecular dynamics simulations of Gly-12-->Val mutant of p21(ras): dynamic inhibition mechanism.
Topics: Binding Sites; Glycine; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hydrogen Peroxide; Hydrolysis; Lysine; Models, Molecular; Mutation; Point Mutation; Protein Structure, Secondary; Proto-Oncogene Proteins p21(ras); Protons; Software; Time Factors; Valine | 2001 |
Limited proteolysis of Escherichia coli cytidine 5'-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Carbon-Nitrogen Ligases; Catalysis; Circular Dichroism; Cytidine Triphosphate; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Glutaminase; Glutamine; Guanosine Triphosphate; Hydrolysis; Kinetics; Lysine; Models, Chemical; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Sequence Homology, Amino Acid; Time Factors; Trypsin | 2003 |
Probing the binding pocket and endocytosis of a G protein-coupled receptor in live cells reported by a spin-labeled substance P agonist.
Topics: Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Electron Spin Resonance Spectroscopy; Endocytosis; Genetic Vectors; Green Fluorescent Proteins; Guanosine Triphosphate; Ligands; Luminescent Proteins; Lysine; Models, Chemical; Oocytes; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Rats; Receptors, Neurokinin-1; RNA, Messenger; Spin Labels; Substance P; Tachykinins; Time Factors; Transfection; Xenopus | 2003 |
Conformational changes in the phosphorylated C-terminal domain of rhodopsin during rhodopsin arrestin interactions.
Topics: Animals; Arginine; Arrestins; Binding Sites; Cattle; Cytoplasm; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Triphosphate; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Peptides; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Rhodopsin; Serine; Signal Transduction | 2004 |
Characterization of three essential residues in the conserved ATP-binding region of Epstein-Barr virus thymidine kinase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Conserved Sequence; Cytidine Triphosphate; Glycine; Guanosine Triphosphate; Herpesvirus 4, Human; Humans; Lysine; Magnesium; Manganese; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Alignment; Sequence Homology, Amino Acid; Threonine; Thymidine Kinase; Thymine Nucleotides; Zinc | 2005 |
Structural insights into fusidic acid resistance and sensitivity in EF-G.
Topics: Crystallography, X-Ray; Drug Resistance, Bacterial; Fusidic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Lysine; Models, Molecular; Mutation; Peptide Elongation Factor G; Protein Structure, Tertiary; Structure-Activity Relationship; Thermus thermophilus | 2005 |
Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains.
Topics: Adaptor Proteins, Signal Transducing; ADP-Ribosylation Factor 1; Amino Acid Sequence; Binding Sites; Binding, Competitive; Biotin; Blood Proteins; Catalytic Domain; Fluorescence Resonance Energy Transfer; GTPase-Activating Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Isoenzymes; Kinetics; Liposomes; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Fragments; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C delta; Phospholipids; Phosphoproteins; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Succinimides; Type C Phospholipases | 2005 |
Analysis of the GTPase activity and active sites of the NG domains of FtsY and Ffh from Streptomyces coelicolor.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Conserved Sequence; Endopeptidase K; GTP Phosphohydrolases; Guanosine Triphosphate; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Signal Recognition Particle; Streptomyces coelicolor | 2006 |
A novel lysine-rich domain and GTP binding motifs regulate the nucleolar retention of human guanine nucleotide binding protein, GNL3L.
Topics: Active Transport, Cell Nucleus; Amino Acid Motifs; beta Karyopherins; Cell Nucleolus; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Lysine; Nuclear Localization Signals; Nuclear Proteins; Protein Structure, Tertiary | 2006 |
Characterization of the Rab7K157N mutant protein associated with Charcot-Marie-Tooth type 2B.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Asparagine; Cell Cycle Proteins; Charcot-Marie-Tooth Disease; Conserved Sequence; ErbB Receptors; Guanosine Triphosphate; Humans; Hydrolysis; Lysine; Mutation, Missense; Nuclear Proteins; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; RNA Interference | 2008 |
Drosophila GoLoco-protein Pins is a target of Galpha(o)-mediated G protein-coupled receptor signaling.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Cycle Proteins; Drosophila melanogaster; Drosophila Proteins; Frizzled Receptors; GTP-Binding Protein alpha Subunits, Gi-Go; GTPase-Activating Proteins; Guanine Nucleotide Dissociation Inhibitors; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Lysine; Molecular Sequence Data; Nerve Tissue Proteins; Receptors, G-Protein-Coupled; Sequence Alignment; Signal Transduction; Two-Hybrid System Techniques | 2009 |
Characterization of a Ras mutant with identical GDP- and GTP-bound structures .
Topics: Animals; Catalysis; Chlorocebus aethiops; COS Cells; Crystallography, X-Ray; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Lysine; Mutant Proteins; Mutation; Protein Conformation; ras Proteins; Substrate Specificity; Thermodynamics | 2009 |
Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.
Topics: Amino Acid Sequence; Cell Line; Chromatography, Affinity; Guanosine Triphosphate; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); raf Kinases; ras Proteins; Tandem Mass Spectrometry; Ubiquitination | 2011 |
The guanine cap of human guanylate-binding protein 1 is responsible for dimerization and self-activation of GTP hydrolysis.
Topics: Amino Acid Motifs; Amino Acid Substitution; Arginine; Binding Sites; Databases, Protein; Dimerization; Enzyme Activation; GTP-Binding Proteins; Guanine; Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Protein Binding; Protein Conformation; Recombinant Proteins | 2012 |
Regulation of RAS oncogenicity by acetylation.
Topics: Acetylation; Animals; Chlorocebus aethiops; COS Cells; Genes, ras; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; HEK293 Cells; HeLa Cells; Humans; Lysine; Mutagenesis, Site-Directed; Prenylation; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; ras Proteins; Structure-Activity Relationship | 2012 |
Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus.
Topics: Amino Acid Substitution; Crystallization; Crystallography, X-Ray; DNA Repair Enzymes; Glycine; Guanosine Triphosphate; Humans; Lysine; Mutation; Phosphoric Monoester Hydrolases; Protein Conformation | 2013 |
A kinetic safety gate controlling the delivery of unnatural amino acids to the ribosome.
Topics: Bacterial Proteins; Boron Compounds; Escherichia coli; Fluorescent Dyes; Guanosine Triphosphate; Kinetics; Lysine; Models, Molecular; Peptide Elongation Factor Tu; Ribosomes; RNA, Transfer; Thermus thermophilus | 2013 |
Evaluating the conformation and binding interface of cap-binding proteins and complexes via ultraviolet photodissociation mass spectrometry.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Dithiothreitol; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4F; Eukaryotic Initiation Factor-4G; Guanosine Triphosphate; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Plant Proteins; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Triticum | 2013 |
Degradation of activated K-Ras orthologue via K-Ras-specific lysine residues is required for cytokinesis.
Topics: Cytokinesis; Dictyostelium; Guanosine Triphosphate; Humans; Lysine; Protein Stability; Proteolysis; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Protozoan Proteins; ras Proteins; Ubiquitin-Protein Ligases; Ubiquitination | 2014 |
The C-terminal helix in the YjeQ zinc-finger domain catalyzes the release of RbfA during 30S ribosome subunit assembly.
Topics: Arginine; Binding Sites; Circular Dichroism; Enzyme Stability; Escherichia coli; Escherichia coli Proteins; GTP Phosphohydrolases; Guanosine Triphosphate; Lysine; Models, Molecular; Ribosomal Proteins; Ribosome Subunits, Small, Bacterial; Zinc Fingers | 2015 |
Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.
Topics: Amino Acids; Animals; Autophagy; Cell Line, Tumor; Enzyme Activation; Feedback, Physiological; Guanosine Triphosphate; HEK293 Cells; Humans; Immunoblotting; Lysine; Lysosomes; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Knockout; Microscopy, Confocal; Models, Biological; Monomeric GTP-Binding Proteins; Multiprotein Complexes; NIH 3T3 Cells; Protein Binding; RNA Interference; S-Phase Kinase-Associated Proteins; TOR Serine-Threonine Kinases; Ubiquitination | 2015 |
Small GTP-binding protein Ran is regulated by posttranslational lysine acetylation.
Topics: Acetylation; Animals; Catalysis; Cell Cycle Proteins; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Humans; Lysine; Mice; Nuclear Proteins; Protein Binding; Protein Processing, Post-Translational; ran GTP-Binding Protein; Rats; Sirtuins | 2015 |
The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A).
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Gene Expression Regulation; Guanosine Triphosphate; Humans; Lysine; Methyltransferases; Organ Specificity; Peptide Elongation Factor 1; Protein Binding; Protein Biosynthesis; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Rats; RNA, Messenger; RNA, Transfer, Amino Acyl; Sequence Alignment; Sequence Homology, Amino Acid | 2017 |
Human Rab small GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system.
Topics: Acylation; Endosomes; Guanosine Triphosphate; Histidine; Humans; Intracellular Membranes; Isoenzymes; Kinetics; Lipid Bilayers; Liposomes; Lysine; Myosin Heavy Chains; Myosin Type V; Oleic Acids; Peptide Fragments; Protein Interaction Domains and Motifs; Protein Interaction Mapping; Protein Prenylation; Protein Processing, Post-Translational; rab GTP-Binding Proteins; Recombinant Fusion Proteins; Succinates | 2017 |
Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils.
Topics: Actin Cytoskeleton; Actins; Actomyosin; Animals; Anti-Bacterial Agents; Cytoskeletal Proteins; Escherichia coli; Guanosine Triphosphate; Lysine; Mice; Myosin Heavy Chains; Neutrophils; rho GTP-Binding Proteins; Transcription Factors | 2022 |