Page last updated: 2024-08-17

lysine and fibrin

lysine has been researched along with fibrin in 126 studies

Research

Studies (126)

Timeframe	Studies, this research(%)	All Research%
pre-1990	62 (49.21)	18.7374
1990's	35 (27.78)	18.2507
2000's	18 (14.29)	29.6817
2010's	9 (7.14)	24.3611
2020's	2 (1.59)	2.80

Authors

Authors	Studies
Imanari, T; Pisano, JJ; Wilcox, GM	1
Finlayson, JS; Folk, JE	1
Senf, L	1
Collen, D; Rákóczi, I; Wiman, B	1
Cederholm-Williams, SA; Swain, A	1
Lubinus, J; Zimmermann, RE	1
Müllertz, S	1
Beck, EA; Furlan, M; Perret, BA; Seelich, T	1
Wallén, P; Wiman, B	1
Kang, EP; Triantaphyllopoulos, DC	1
Koutský, J; Rybák, M; Rybáková, B	1
Kohnert, U; Lechner, M; Lill, H; Martin, U; Opitz, U; Prinz, H; Rudolph, R; Stern, A; Verheijen, JH; Weening-Verhoeff, EJ	1
Coyne, CP; DeBowes, RM; Smith, JE	1
Fischer, B; Noll, F; Will, H; Zacharias, U	1
Bas Leerink, C; Bouma, BN; Duif, PF; Gimpel, JA; Kortlandt, W; van Rijn, HJ	1
Anglés-Cano, E; Laplaud, PM; Rouy, D; Saboureau, M	1
Anglés-Cano, E; Fleury, V	1
Fischer, B	1
Howard, SC; Welply, JK; Wittwer, AJ	1
Fischer, B; Will, H; Zacharias, U	1
Marotti, KR; Quax, PH; Rehberg, EF; van Leeuwen, RT; Verheijen, JH; Weening-Verhoeff, EJ	1
Mulichak, AM; Tulinsky, A	1
Lorand, L; Parameswaran, KN; Velasco, PT; Wilson, J	1
Boel, E; Foster, D; Johannessen, M; Petersen, LC	1
Bulens, F; Collen, D; Lijnen, HR; Nelles, L; Tulinsky, A; Vandamme, AM	1
Bang, NU; Jaskunas, SR; Vlahos, CJ; Wilhelm, OG	1
Miles, LA; Plow, EF	1
Chang, BI; Chang, LC; Gong, CC; Lou, KL; Shi, GY; Wu, DH; Wu, HL	1
Collen, D; Lijnen, HR	1
Church, FC; Kalayanamit, T; Meade, JB; Noyes, CM; Pratt, CW; Sherrill, GB; Tobin, RB	1
Caspers, MP; Chang, GT; de Munk, GA; Enger-Valk, BE; Pouwels, PH; Verheijen, JH	1
Gordon, BR; Harpel, PC; Parker, TS	1
Fok, KF; Hortin, GL; Trimpe, BL	1
Banton, CJ; Overell, BG	1
Bockenstedt, P; Hada, M; Kaminski, M; McDonagh, J	1
Kastrikina, TF; Kudinov, SA; Taran, LD	1
Collen, D; Holvoet, P; Lijnen, HR	1
Pannekoek, H; van Zonneveld, AJ; Veerman, H	1
Klasen, EA; Nieuwenhuizen, W; van Boom, JH; Veeneman, GH; Vermond, A; Voskuilen, M; Zegers, ND	1
Basdevant, A; Bertrand, O; Mirshahi, M; Soria, C; Soria, J	1
Fukao, H; Matsuo, C; Matsuo, O	1
Llinás, M; Mao, B; Park, CH; Tulinsky, A	1
Fukao, H; Matsuo, C; Matsuo, O; Ueshima, S	1
Abe, T; Kasai, K; Kazama, M; Tahara, C	1
Lütjens, A; te Velde, AA; vd Meer, J; vd Veen, EA	1
Baskova, IP; Nikonov, GI	1
Cartwright, T	1
Asquith, RS; Otterburn, MS; Sinclair, WJ	1
Rickli, EE	1
Johnson, AJ; Semar, M; Skoza, L; Tse, AO	1
Doolittle, RF; Weinstein, MJ	1
Chandra, S; Triantaphyllopoulos, DC	1
Cassman, KG; Chen, R; Doolittle, RF; Sharp, JJ; Wooding, GL	1
Blombäck, B; McDonagh, J; McDonagh, RP	1
Host, WR; Rush, BF; Serlin, O	1
Harding, HW; Rogers, GE	1
Finlayson, JS	1
Bronzert, TJ; Finlayson, JS; Peyton, MP; Pisano, JJ	1
Bennett, B; Douglas, AS; Herbert, RJ; Ogston, D	1
Phillips, HM; York, JL	1
George, JN; Reed, CF; Weed, RI	1
Finlayson, JS; Peyton, MP; Pisano, JJ	2
Chen, R; Doolittle, RF; Lau, F	1
Chen, R; Doolittle, RF	1
Finlayson, JS; Nagai, Y; Peyton, MP; Pisano, JJ	1
Cooper, IA; Firkin, BG	1
Doolittle, RF; Fuller, GM	1
Loewy, AG; Matacić, S	1
Downey, J; Gotoh, T; Jacobsen, A; Lorand, L; Tokura, S	1
Brownlee, M; Cerami, A; Vlassara, H	1
Radcliffe, R	1
Suenson, E; Thorsen, S	1
Gaffney, PJ; Joe, F; Masci, PP; Rowe, EA; Whitaker, AN	1
Corcoran, DH; Ferguson, EW; Fretto, LJ; McKee, PA	1
Garman, AJ; Smith, RA	1
Aoki, N; Matsuda, M; Sakata, Y; Tateno, K	1
Egbring, R; Rudchenko, S; Sobel, JH; Trakht, I; Wu, HQ	1
Ingham, K; Lijnen, HR; Medved, L; Novokhatny, V	1
Bakker, AH; Verheijen, JH; Weening-Verhoeff, EJ	1
Padmanabhan, KP; Tulinsky, A; Wu, TP	1
Anglés-Cano, E; Fleury, V; Lijnen, HR	1
Anglés-Cano, E; Grailhe, P; Nieuwenhuizen, W	1
Berg, DH; Berg, DT; Burck, PJ; Grinnell, BW	1
Bakker, AH; Marotti, KR; Rehberg, EF; van der Greef, W; Verheijen, JH	1
Furlan, M; Heinemann, G; Jungo, M; Lämmle, B; Reber, P; Steinmann, C; Wermuth, B	1
Gawinowicz, MA; Sobel, JH	1
Bakker, AH; Nieuwenbroek, NM; Verheijen, JH	1
Brash, JL; Weitz, JI; Woodhouse, KA	1
Madison, EL; Tachias, K	1
Arai, K; Asakura, S; Ishizuka, M; Madoiwa, S; Matsuda, M; Mimuro, J; Sakata, Y; Ueda, Y	1
Boonmark, NW; Lawn, RM; Lou, XJ; Rubin, EM; Schwartz, K; Yang, ZJ; Zhang, JL	1
Endo, A; Hasumi, K; Tachikawa, K	1
Foster, DC; Linde, V; Nielsen, LS; Petersen, LC	1
Bajzar, L; Boffa, MB; Nesheim, ME; Walker, JB; Wang, W	1
Bouma, BN; Dawson, PE; Griffin, JH; Hackeng, TM; Marx, PF; Meijers, JC	1
Booth, NA; Crombie, PW; Lawrie, LC; Mosesson, MW; Ritchie, H	1
Bajzar, L; Fredenburgh, JC; Rischke, JA; Stewart, RJ; Weitz, JI	1
Urano, T	1
Abou-Rebyeh, F; de Heer, E; Floege, J; Gawlik, A; Ketteler, M; Kitahara, M; Westenfeld, R	1
Chavakis, T; Colman, RW; Isordia-Salas, I; Pixley, RA; Preissner, KT	1
Rothman, VL; Sharma, MC; Sharma, MR; Tuszynski, GP	1
Anglés-Cano, E; Ho-Tin-Noé, B; Medved, L; Tsurupa, G	1
INGEMANSON, B	1
BIEZUNSKI, N; DE VRIES, A; KATCHALSKI, E; SHAFRIR, E	1
Atsumi, T; Ieko, M; Koike, T; Yasuda, S	1
Belczewski, AR; Boffa, MB; Ho, J; Jia, Z; Koschinsky, ML; Taylor, FB	1
Asakura, H; Asamura, R; Hayashi, T; Miyamoto, KI; Morishita, E; Nakao, S; Ontachi, Y; Yamazaki, M	1
Anglés-Cano, E; Ho-Tin-Noé, B; Lijnen, HR; Rojas, G; Vranckx, R	1
Andersson, M; Berntsson, P; Cronet, P; Furebring, C; Hager, AC; Harrysson, A; Hendriks, D; Knecht, W; Stenhamre, H; Willemse, J; Wissing, BM	1
Baker, S; Matsuka, YV; Nunez, L; Severina, E	1
Hoffman, M; Lenkowski, A; Lockhart, E; Sauls, DL; Warren, ME; Wilhelm, SE	1
Anglés-Cano, E; Boyer-Neumann, C; Carvajal, Z; Marchi, RC; Weisel, JW	1
Anglés-Cano, E; Lamanuzzi, LB; Medved, L; Pechik, I; Tsurupa, G; Yakovlev, S	1
Doolittle, RF; Pandi, L	1
Ahn, JH; Kim, JS; Kim, SJ; Lee, EK; Lee, HJ; Lee, TH; Yoon, Y; Yu, HK	1
Wang, W	1
Buelens, K; Compernolle, G; Declerck, PJ; Gils, A; Mishra, N; Theyskens, S	1
Longstaff, C; Silva, MM; Thelwell, C; Williams, SC	1
Chen, J; Chowdhury, F; Doğanay, S; Ha, T; Hong, Y; Huang, B; Jia, H; Jia, Q; Li, Y; Lin, LJ; Poh, YC; Seong, J; Singh, R; Tajik, A; Tan, Y; Wang, L; Wang, N; Wang, Y; Wei, F; Wu, DC; Yi, H; Zhang, S; Zhang, Y	1
Nowak, P; Tadeusiewicz, J	1
Brain, C; Georgiev, G; Kim, PY; Klemmer, A; Lionikiene, AS; Mitchell, JL; Mutch, NJ	1
Kamaludin, AA; Komar, J; Longstaff, C; Madureira, PA; Miller, VA; Sahni, G; Sharma, V; Thelwell, C; Waisman, DM	1
Barrett, A; Clendenen, N; D'Alessandro, A; Darula, Z; Hansen, KC; Henderson, R; Issaian, A; Schmitt, LR	1
Cao, J; Du, J; Geng, F; Pan, D; Wang, Y; Zhou, C	1
Cline, HM; Flick, MJ; Groeneveld, DJ; Hansen, KC; Hur, WS; Luyendyk, JP; Poole, LG; Sang, Y; Schmitt, LR; Schulte, A; Wolberg, AS	1

Reviews

9 review(s) available for lysine and fibrin

Article	Year
The epsilon-(gamma-glutamyl)lysine crosslink and the catalytic role of transglutaminases. Advances in protein chemistry, 1977, Volume: 31 Topics: Animals; Beta-Globulins; Chemical Phenomena; Chemistry; Dipeptides; Factor XIII; Female; Fibrin; Fibrinogen; gamma-Glutamyltransferase; Humans; Lysine; Male; Pregnancy; Skin; Tissue Distribution	1977
[The enzymatic linkage of fibrinogenesis and fibrinolysis (author's transl)]. Klinische Wochenschrift, 1978, Aug-15, Volume: 56, Issue:16 Topics: Aminocaproates; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Dexamethasone; Factor XII; Fibrin; Fibrinolysin; Fibrinolysis; Hemostasis; Humans; L Cells; Lysine; Mice; Peptide Hydrolases; Plasminogen; Plasminogen Activators; Receptors, Cell Surface; Simian virus 40; Streptokinase; Tranexamic Acid; Urokinase-Type Plasminogen Activator	1978
Lp(a): an interloper into the fibrinolytic system? Thrombosis and haemostasis, 1990, Jun-28, Volume: 63, Issue:3 Topics: Amino Acid Sequence; Apolipoproteins A; Base Sequence; Binding, Competitive; Blood Proteins; Cardiovascular Diseases; Fibrin; Fibrinogen; Humans; Lectins, C-Type; Lipoprotein(a); Lipoproteins; Lysine; Molecular Sequence Data; Molecular Structure; Plasminogen; Plasminogen Activators; Protein Binding; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator	1990
The fibrinolytic system in man. Critical reviews in oncology/hematology, 1986, Volume: 4, Issue:3 Topics: alpha-2-Antiplasmin; alpha-Macroglobulins; Animals; Behcet Syndrome; Binding Sites; Disseminated Intravascular Coagulation; Embolism; Female; Fibrin; Fibrinolysin; Fibrinolysis; Fibrinolytic Agents; Humans; In Vitro Techniques; Kidney Diseases; Kinetics; Liver Diseases; Lysine; Plasminogen; Plasminogen Activators; Plasminogen Inactivators; Pregnancy; Streptokinase; Thrombosis; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	1986
Isopeptide crosslinks--their occurrence and importance in protein structure. Angewandte Chemie (International ed. in English), 1974, Volume: 13, Issue:8 Topics: Animals; Aspartic Acid; Binding Sites; Chemical Phenomena; Chemistry; Fibrin; Glutamates; Lysine; Nutritional Physiological Phenomena; Peptides; Protein Binding; Protein Conformation; Protein Denaturation; Structure-Activity Relationship; Wool	1974
The biochemistry of the fibrinolytic enzyme system in man. Angiologica, 1968, Volume: 5, Issue:2 Topics: Amino Acids; Aminocaproates; Antifibrinolytic Agents; Blood Protein Electrophoresis; Fibrin; Fibrinolysin; Fibrinolysis; Fibrinolytic Agents; Lysine; Molecular Weight; Plasminogen; Streptokinase; Trypsin; Ultracentrifugation	1968
[Regulatory mechanism of fibrinolysis system by thrombin activatable fibrinolysis inhibitor (TAFI)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2000, Volume: 116, Issue:5 Topics: Binding Sites; Blood Coagulation; Carboxypeptidase B2; Carboxypeptidases; Fibrin; Fibrinolysis; Humans; Lysine; Thrombin; Thrombomodulin	2000
Beta2-glycoprotein I, anti-beta2-glycoprotein I, and fibrinolysis. Thrombosis research, 2004, Volume: 114, Issue:5-6 Topics: Animals; Antibodies, Antiphospholipid; Antibodies, Monoclonal; Anticoagulants; beta 2-Glycoprotein I; Cell Membrane; Factor XI; Fibrin; Fibrinolysin; Fibrinolysis; Glycoproteins; Humans; Lysine; Mice; Mice, Knockout; Models, Biological; Plasminogen; Protein Binding; Protein Structure, Tertiary; Tissue Plasminogen Activator	2004
[The role of post-translational modification of fibrinogen in the pathogenesis of thrombosis]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2015, Volume: 38, Issue:224 Topics: Extracellular Space; Fibrin; Fibrinogen; Fibrinolysis; Glycation End Products, Advanced; Halogenation; Homocysteine; Humans; Lysine; Protein Processing, Post-Translational; Thrombosis	2015

Other Studies

117 other study(ies) available for lysine and fibrin

Article	Year
Sensitive radiochemical esterolytic assays for urokinase. Clinica chimica acta; international journal of clinical chemistry, 1976, Sep-06, Volume: 71, Issue:2 Topics: Adult; Dipeptides; Endopeptidases; Female; Fibrin; Fibrinolysin; Glycine; Humans; Hydrogen-Ion Concentration; Lysine; Male; Methanol; Temperature; Tosylarginine Methyl Ester; Tritium; Urokinase-Type Plasminogen Activator	1976
[In vitro studies and model calculations on the kinetics of fibrinolysis with streptokinase]. Folia haematologica (Leipzig, Germany : 1928), 1979, Volume: 106, Issue:5-6 Topics: Binding Sites; Enzyme Activation; Fibrin; Fibrinolysin; Fibrinolysis; Humans; In Vitro Techniques; Kinetics; Lysine; Models, Chemical; Streptokinase	1979
On the biological significance of the specific interaction between fibrin, plasminogen and antiplasmin. Biochimica et biophysica acta, 1978, May-03, Volume: 540, Issue:2 Topics: Blood Proteins; Fibrin; Fibrinolysin; Glutamates; Humans; Lysine; Plasminogen	1978
The effect of fibrinogen degradation products and some lysine analogues on the dissociation of plasmin(ogen)-fibrin complexes. Thrombosis research, 1979, Volume: 16, Issue:5-6 Topics: Aminocaproic Acid; Animals; Cattle; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Fibrinolysis; Humans; Lysine; Plasminogen; Protein Binding; Tranexamic Acid	1979
The fibrinolytic system. Scandinavian journal of haematology. Supplementum, 1979, Volume: 34 Topics: Amino Acids; Antifibrinolytic Agents; Binding Sites; Endopeptidases; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Humans; Lysine; Plasminogen	1979
A thiocholine ester of cinnamic acid inhibits crosslinking of fibrin without specific binding to donor lysines. Thrombosis and haemostasis, 1979, Jun-30, Volume: 41, Issue:4 Topics: Chemical Phenomena; Chemistry; Cinnamates; Cross-Linking Reagents; Factor XIII; Fibrin; Lysine; Thiocholine	1979
The specific interaction between plasminogen and fibrin. A physiological role of the lysine binding site in plasminogen. Thrombosis research, 1977, Volume: 10, Issue:2 Topics: Amino Acid Sequence; Binding Sites; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Fibrin; Humans; Lysine; Plasminogen	1977
Fibrin digestion by thrombin: the significance of the arginyl and lysyl bonds. Thrombosis research, 1977, Volume: 11, Issue:3 Topics: Arginine; Blood Coagulation; Dialysis; Fibrin; Fibrinogen; Glyoxal; Humans; Lysine; Peptides; Spectrum Analysis; Thrombin	1977
[Plasminogen activator and other trypsin-like proteases in the uterus wall and their participation on the tissue bleeding (author's transl)]. Archiv fur Gynakologie, 1975, Dec-16, Volume: 220, Issue:1 Topics: Aminocaproates; Aprotinin; Caseins; Cervix Uteri; Endometrium; Female; Fibrin; Fibrinolysis; Glycine; Humans; Lysine; Menstruation; Myometrium; Peptide Fragments; Peptide Hydrolases; Plasminogen Activators; Protease Inhibitors; Time Factors; Tosylarginine Methyl Ester; Trypsin; Uterus	1975
Biochemical properties of the kringle 2 and protease domains are maintained in the refolded t-PA deletion variant BM 06.022. Protein engineering, 1992, Volume: 5, Issue:1 Topics: Amidohydrolases; Escherichia coli; Fibrin; Fibrinolysin; Inclusion Bodies; Lysine; Mutation; Plasminogen; Protein Conformation; Recombinant Proteins; Tissue Plasminogen Activator	1992
Pharmacologic evaluation of factor XIIIa-like enzyme activity in equine plasma as a potential therapeutic avenue for the inhibition of fibrinous tissue. American journal of veterinary research, 1992, Volume: 53, Issue:5* Topics: Analysis of Variance; Animals; Arginine; Cefuroxime; Densitometry; Electrophoresis, Cellulose Acetate; Fibrin; Fibrinogen; Glycine; Histamine; Horses; Hydroxylamine; Hydroxylamines; Iodoacetamide; Lysine; Phenelzine; Spectrophotometry, Ultraviolet; Transglutaminases	1992
Characterization of human tissue-type plasminogen activator with monoclonal antibodies: mapping of epitopes and binding sites for fibrin and lysine. Thrombosis and haemostasis, 1992, Jan-23, Volume: 67, Issue:1 Topics: Antibodies, Monoclonal; Binding Sites; Epitopes; Fibrin; Humans; Immunoblotting; Immunochemistry; Immunoenzyme Techniques; Ligands; Lysine; Tissue Plasminogen Activator	1992
Lysine-binding heterogeneity of Lp(a): consequences for fibrin binding and inhibition of plasminogen activation. Thrombosis and haemostasis, 1992, Aug-03, Volume: 68, Issue:2 Topics: Binding Sites; Chromatography, Affinity; Fibrin; Humans; In Vitro Techniques; Lipoprotein(a); Lysine; Plasminogen; Protein Binding; Sepharose	1992
Hedgehog lipoprotein(a) is a modulator of activation of plasminogen at the fibrin surface. An in vitro study. Arteriosclerosis and thrombosis : a journal of vascular biology, 1992, Volume: 12, Issue:2 Topics: Adsorption; Animals; Blood Proteins; Fibrin; Hedgehogs; Lipoprotein(a); Lipoproteins; Lysine; Male; Plasminogen; Tissue Plasminogen Activator	1992
Characterization of the binding of plasminogen to fibrin surfaces: the role of carboxy-terminal lysines. Biochemistry, 1991, Jul-30, Volume: 30, Issue:30 Topics: Antibodies; Binding Sites; Electrophoresis; Fibrin; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Plasminogen; Radioligand Assay	1991
Binding of one-chain tissue-type plasminogen activator to fibrin, partially plasmin-degraded fibrin, lysine and heparin. Biomedica biochimica acta, 1991, Volume: 50, Issue:1 Topics: Chromatography, Agarose; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinolysin; Heparin; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Melanoma; Sodium Chloride; Tissue Plasminogen Activator; Tumor Cells, Cultured	1991
Oligosaccharides at each glycosylation site make structure-dependent contributions to biological properties of human tissue plasminogen activator. Glycobiology, 1991, Volume: 1, Issue:4 Topics: 1-Deoxynojirimycin; Fibrin; Glucosamine; Glycoproteins; Glycosylation; Humans; Lysine; Neuraminidase; Oligosaccharides; Substrate Specificity; Tissue Plasminogen Activator	1991
Effects of monoclonal antibodies on tissue-type plasminogen activator (t-PA) binding to lysine, fibrin and heparin and on fibrin-mediated enhancement of one-chain t-PA amidolytic activity. Biological chemistry Hoppe-Seyler, 1991, Volume: 372, Issue:4 Topics: Antibodies, Monoclonal; Binding Sites; Fibrin; Heparin; Lysine; Tissue Plasminogen Activator	1991
Involvement of aspartic and glutamic residues in kringle-2 of tissue-type plasminogen activator in lysine binding, fibrin binding and stimulation of activity as revealed by chemical modification and oligonucleotide-directed mutagenesis. Protein engineering, 1990, Volume: 4, Issue:2 Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Ethyldimethylaminopropyl Carbodiimide; Fibrin; Glutamates; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptide Fragments; Plasminogen; Protein Engineering; Tissue Plasminogen Activator	1990
Structure of the lysine-fibrin binding subsite of human plasminogen kringle 4. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1990, Volume: 1, Issue:6 Topics: Amino Acid Sequence; Binding Sites; Fibrin; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Plasminogen; Protein Binding; Protein Conformation; Structure-Activity Relationship; X-Ray Diffraction	1990
Labeling of epsilon-lysine crosslinking sites in proteins with peptide substrates of factor XIIIa and transglutaminase. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:21 Topics: Amino Acid Sequence; Animals; Binding Sites; Cadaverine; Cross-Linking Reagents; Crystallins; Fibrin; Indicators and Reagents; Kinetics; Lens, Crystalline; Lysine; Molecular Sequence Data; Oligopeptides; Rabbits; Substrate Specificity; Transglutaminases	1990
Quenching of the amidolytic activity of one-chain tissue-type plasminogen activator by mutation of lysine-416. Biochemistry, 1990, Apr-10, Volume: 29, Issue:14 Topics: Amidohydrolases; Base Sequence; Binding Sites; Cloning, Molecular; Fibrin; Humans; Kinetics; Lysine; Macromolecular Substances; Molecular Sequence Data; Mutation; Sequence Homology, Nucleic Acid; Tissue Plasminogen Activator	1990
Biochemical and functional characterization of human tissue-type plasminogen activator variants with mutagenized kringle domains. The Journal of biological chemistry, 1990, Jul-25, Volume: 265, Issue:21 Topics: Animals; Base Sequence; Binding Sites; Cricetinae; DNA; DNA Mutational Analysis; Fibrin; Fibrinogen; Fibrinolysis; Humans; Lysine; Molecular Sequence Data; Plasminogen; Protein Binding; Recombinant Proteins; Tissue Plasminogen Activator	1990
Functional properties of the recombinant kringle-2 domain of tissue plasminogen activator produced in Escherichia coli. The Journal of biological chemistry, 1990, Aug-25, Volume: 265, Issue:24 Topics: Cloning, Molecular; Escherichia coli; Fibrin; Humans; Kinetics; Lysine; Plasminogen Inactivators; Protein Binding; Protein Conformation; Recombinant Proteins; Restriction Mapping; Sulfur Radioisotopes; Tissue Plasminogen Activator	1990
Interaction of plasminogen and fibrin in plasminogen activation. The Journal of biological chemistry, 1990, Nov-15, Volume: 265, Issue:32 Topics: Aminocaproic Acid; Fibrin; Fibrin Fibrinogen Degradation Products; Humans; Kinetics; Lysine; Molecular Weight; Peptide Fragments; Plasminogen; Tissue Plasminogen Activator	1990
Structural and functional properties of human alpha-thrombin, phosphopyridoxylated alpha-thrombin, and gamma T-thrombin. Identification of lysyl residues in alpha-thrombin that are critical for heparin and fibrin(ogen) interactions. The Journal of biological chemistry, 1989, Nov-05, Volume: 264, Issue:31 Topics: Antibodies, Monoclonal; Antithrombin III; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Fibrin; Fibrinogen; Heparin; Humans; Immunoassay; Lysine; Peptide Fragments; Pyridoxal Phosphate; Structure-Activity Relationship; Thrombin	1989
Binding of tissue-type plasminogen activator to lysine, lysine analogues, and fibrin fragments. Biochemistry, 1989, Sep-05, Volume: 28, Issue:18 Topics: Animals; Binding Sites; Chromatography, Affinity; Cricetinae; Electrophoresis, Polyacrylamide Gel; Fibrin; Humans; Ligands; Lysine; Tissue Plasminogen Activator	1989
Plasmin catalyzes binding of lipoprotein (a) to immobilized fibrinogen and fibrin. Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:10 Topics: Arteriosclerosis; Fibrin; Fibrinogen; Fibrinolysin; Humans; In Vitro Techniques; Lipoprotein(a); Lipoproteins; Lipoproteins, LDL; Lysine; Pancreatic Elastase; Protein Binding; Structure-Activity Relationship; Trypsin	1989
Plasmin's peptide-binding specificity: characterization of ligand sites in alpha 2-antiplasmin. Thrombosis research, 1989, Jun-15, Volume: 54, Issue:6 Topics: alpha-2-Antiplasmin; Arginine; Binding Sites; Fibrin; Fibrinolysin; Ligands; Lysine; Peptide Mapping; Peptides; Phosphoric Monoester Hydrolases; Protein Binding	1989
Fibrin binding. An essential property of anisoylated plasminogen streptokinase activator complex. Drugs, 1987, Volume: 33 Suppl 3 Topics: Anistreplase; Chromatography, High Pressure Liquid; Fibrin; Fibrinolytic Agents; In Vitro Techniques; Lysine; Peptide Fragments; Plasminogen; Protein Binding; Streptokinase	1987
Covalent crosslinking of von Willebrand factor to fibrin. Blood, 1986, Volume: 68, Issue:1 Topics: Blood Coagulation Tests; Cross-Linking Reagents; Factor XIII; Fibrin; Fibrinogen; Gels; Glutamine; Humans; In Vitro Techniques; Lysine; Putrescine; Transglutaminases; von Willebrand Factor	1986
Kinetic characteristics of fibrinogen and fibrin hydrolysis by plasmin 1 and 2 and miniplasmin. Thrombosis research, 1986, Mar-01, Volume: 41, Issue:5 Topics: Binding Sites; Fibrin; Fibrinogen; Fibrinolysin; Humans; Hydrolysis; Kinetics; Lysine; Peptide Fragments	1986
A monoclonal antibody directed against the high-affinity lysine-binding site (LBS) of human plasminogen. Role of LBS in the regulation of fibrinolysis. European journal of biochemistry, 1986, May-15, Volume: 157, Issue:1 Topics: alpha-2-Antiplasmin; Animals; Antibodies, Monoclonal; Binding Sites; Binding, Competitive; Fibrin; Fibrinolysin; Fibrinolysis; Lysine; Mathematics; Mice; Mice, Inbred BALB C; Plasminogen; Radioimmunoassay; Tissue Plasminogen Activator	1986
On the interaction of the finger and the kringle-2 domain of tissue-type plasminogen activator with fibrin. Inhibition of kringle-2 binding to fibrin by epsilon-amino caproic acid. The Journal of biological chemistry, 1986, Oct-25, Volume: 261, Issue:30 Topics: Aminocaproates; Aminocaproic Acid; Animals; Binding Sites; Chromatography, Affinity; Fibrin; Humans; Lysine; Mice; Peptide Fragments; Protein Conformation; Recombinant Proteins; Tissue Plasminogen Activator	1986
Fibrinogen lysine residue A alpha 157 plays a crucial role in the fibrin-induced acceleration of plasminogen activation, catalyzed by tissue-type plasminogen activator. The Journal of biological chemistry, 1987, May-05, Volume: 262, Issue:13 Topics: Amino Acids; Fibrin; Fibrinogen; Humans; Lysine; Tissue Plasminogen Activator	1987
Glycosylation of human fibrinogen and fibrin in vitro. Its consequences on the properties of fibrin(ogen). Thrombosis research, 1987, Nov-01, Volume: 48, Issue:3 Topics: Adenosine Diphosphate; Blood Coagulation; Factor XIII; Fibrin; Fibrinogen; Fibrinolysis; Glucose; Glycosylation; Humans; Kinetics; Lysine; Platelet Aggregation	1987
Characterization of plasminogen activator produced by an established cell line from human ovary. Journal of cellular physiology, 1988, Volume: 134, Issue:2 Topics: Cell Line; Chemical Phenomena; Chemistry; Female; Fibrin; Humans; Isoelectric Point; Lysine; Ovary; Plasminogen Activators	1988
Lysine/fibrin binding sites of kringles modeled after the structure of kringle 1 of prothrombin. Proteins, 1988, Volume: 3, Issue:2 Topics: Amino Acid Sequence; Binding Sites; Calorimetry; Computer Simulation; Fibrin; Humans; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Plasminogen; Protein Conformation; Prothrombin	1988
New type of plasminogen activator produced by an established cell line from human ovary. Thrombosis research. Supplement, 1988, Volume: 8 Topics: Cell Line; Female; Fibrin; Humans; Isoelectric Point; Kinetics; Lysine; Ovary; Plasminogen Activators	1988
Quantitative analysis of fibrin-binding affinity of fibrinolytic components by frontal affinity chromatography. Thrombosis research. Supplement, 1988, Volume: 8 Topics: Arginine; Chromatography, Affinity; Fibrin; Lysine; Peptide Fragments; Plasminogen; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	1988
Glycosylation of human fibrinogen in vivo. Diabetologia, 1985, Volume: 28, Issue:2 Topics: Adult; Binding Sites; Blood Glucose; Diabetes Mellitus, Type 1; Female; Fibrin; Fibrinogen; Humans; Lysine; Male; Middle Aged	1985
[Destabilase: an enzyme of medicinal leech salivary gland secretion hydrolyzes the isopeptide bonds in stabilized fibrin]. Biokhimiia (Moscow, Russia), 1985, Volume: 50, Issue:3 Topics: Animals; Endopeptidases; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Glutamates; Hydrolysis; Kinetics; Leeches; Lysine; Peptide Hydrolases; Salivary Glands; Sulfhydryl Reagents	1985
The plasminogen activator of vampire bat saliva. Blood, 1974, Volume: 43, Issue:3 Topics: Animals; Arginine; Azo Compounds; Benzoates; Blood Coagulation Tests; Blood Platelets; Chiroptera; Chromatography, DEAE-Cellulose; Chromatography, Gel; Collagen; Electrophoresis; Enzyme Activation; Esters; Fibrin; Fibrinogen; Fibrinolysis; Fibrinolytic Agents; Humans; Immunodiffusion; Lysine; Molecular Weight; Plasminogen; Proteins; Saliva; Tosyl Compounds	1974
Comparative activities of amino acid and polypeptide inhibitors on natural and synthetic substrates. Annals of the New York Academy of Sciences, 1968, Jun-28, Volume: 146, Issue:2 Topics: Amino Acids; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Tests; Caseins; Fibrin; Fibrinogen; Fibrinolysin; Fibrinolysis; Humans; Kinetics; Lysine; Peptides; Plasminogen; Streptokinase; Time Factors; Trypsin Inhibitors	1968
Differential specificities of the thrombin, plasmin and trypsin with regard to synthetic and natural substrates and inhibitors. Biochimica et biophysica acta, 1972, Feb-28, Volume: 258, Issue:2 Topics: Amino Acids; Animals; Arginine; Blood Coagulation Tests; Cattle; Esters; Fibrin; Fibrinogen; Fibrinolysin; Fibrinolysis; Glycine max; Hydrolysis; Lysine; Peptides; Structure-Activity Relationship; Thrombin; Tosyl Compounds; Trypsin; Trypsin Inhibitors	1972
Digestion of fibrin by thrombin. Biochimica et biophysica acta, 1973, Nov-11, Volume: 328, Issue:1 Topics: Chlorine; Chromatography, Affinity; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Fibrinolysin; Humans; Lysine; Plasminogen; Sodium Dodecyl Sulfate; Solubility; Spectrophotometry, Ultraviolet; Thrombin; Tosyl Compounds; Ultrafiltration	1973
Correlation of the mode of fibrin polymerization with the pattern of cross-linking. Annals of the New York Academy of Sciences, 1972, Dec-08, Volume: 202 Topics: Amino Acid Sequence; Amino Acids; Animals; Blood Coagulation; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Disulfides; Fibrin; Glutamine; Humans; Lysine; Models, Chemical; Models, Structural; Peptides; Polymers; Protein Conformation; Solubility; Species Specificity; Trypsin	1972
Polypeptide chains of human fibrin: molecular organization in cross-linking. Annals of the New York Academy of Sciences, 1972, Dec-08, Volume: 202 Topics: Amino Acids; Arginine; Blood Coagulation; Carbon Isotopes; Chemical Phenomena; Chemistry; Electrophoresis, Polyacrylamide Gel; Fibrin; Histidine; Humans; Lysine; Macromolecular Substances; Molecular Weight; Peptides; Putrescine; Sodium Dodecyl Sulfate	1972
Hyperalimentation in cirrhotic patients. American journal of surgery, 1972, Volume: 123, Issue:1 Topics: Acid-Base Equilibrium; Acidosis; Alanine Transaminase; Alkaline Phosphatase; Amino Acids; Ammonia; Arginine; Carbon Dioxide; Caseins; Catheterization; Cysteine; Diet Therapy; Fibrin; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Liver Cirrhosis; Lysine; Methionine; Parenteral Nutrition; Phenylalanine; Potassium; Sodium; Threonine; Tryptophan	1972
Formation of the -( -glutamyl) lysine cross-link in hair proteins. Investigation of transamidases in hair follicles. Biochemistry, 1972, Jul-18, Volume: 11, Issue:15 Topics: Animals; Antibodies; Binding Sites; Carbon Isotopes; Caseins; Chromatography, Affinity; Edetic Acid; Electrophoresis; Fibrin; Fibrinogen; Glutamates; Glycine; Guinea Pigs; Hair; Immune Sera; Immunodiffusion; Lysine; Protein Binding; Rabbits; Rats; Sheep; Thrombin; Transferases	1972
Human fibrinogen free of factor XIII: the pursuit of biological zero. Annals of the New York Academy of Sciences, 1972, Dec-08, Volume: 202 Topics: Blood Coagulation; Carbon Isotopes; Chromatography, DEAE-Cellulose; Dialysis; Electrophoresis, Polyacrylamide Gel; Evaluation Studies as Topic; Factor XIII; Fibrin; Fibrinogen; Glutamine; Humans; Immunodiffusion; Lysine; Mercaptoethanol; Methods; Oxidation-Reduction; Peptides; Putrescine; Sodium Dodecyl Sulfate; Solubility	1972
Epsilon-(gamma-glutamyl) lysine cross-links: determination in fibrin from normal and factor XIII-deficient individuals. Annals of the New York Academy of Sciences, 1972, Dec-08, Volume: 202 Topics: Alkylation; Animals; Blood Coagulation; Blood Platelets; Chemical Phenomena; Chemistry; Electrophoresis, Polyacrylamide Gel; Factor XIII; Factor XIII Deficiency; Female; Fibrin; Fibrinogen; Glutamine; Haplorhini; Humans; Hydrogen-Ion Concentration; Lysine; Macaca; Peptides; Plasma; Protein Conformation; Sodium Dodecyl Sulfate; Solubility; Species Specificity; Trypsin	1972
The inhibition of urokinase by alpha 2 -macroglobulin. Clinical science, 1973, Volume: 44, Issue:1 Topics: Animals; Antifibrinolytic Agents; Arginine; Cattle; Dipeptides; Esters; Fibrin; Glycine; Humans; Hydrolysis; Kinetics; Lysine; Macroglobulins; Physical Exertion; Plasminogen; Serum Globulins; Sulfonic Acids; Toluene	1973
Bovine fibrinogen. II. Effects of tyrosine modification on fibrin monomer aggregation. Biochemistry, 1973, Sep-11, Volume: 12, Issue:19 Topics: Acetylation; Amidines; Animals; Blood Coagulation Tests; Cattle; Chemical Phenomena; Chemistry; Fibrin; Fibrinogen; Kinetics; Lysine; Protein Conformation; Protein Denaturation; Tyrosine; Urea	1973
Adhesion of human erythrocytes to glass: the nature of the interaction and the effect of serum and plasma. Journal of cellular physiology, 1971, Volume: 77, Issue:1 Topics: Adhesiveness; Buffers; Chloromercuribenzoates; Erythrocytes; Fibrin; Glass; Hot Temperature; Humans; Hydrogen-Ion Concentration; Lysine; Membrane Potentials; Methods; Microscopy, Phase-Contrast; Muramidase; Protamines; Sulfhydryl Compounds; Time Factors	1971
[Cross-link in fibrin polymerized by factor 13: epsilon-(gamma-glutamyl)lysine]. Science (New York, N.Y.), 1968, May-24, Volume: 160, Issue:3830 Topics: Autoanalysis; Bicarbonates; Blood Coagulation; Blood Coagulation Factors; Chromatography, Ion Exchange; Dialysis; Dipeptides; Edetic Acid; Fibrin; Humans; Lysine; Polymers	1968
Chemical and enzymic detection of protein cross-links. Measurement of epsilon-(gamma-glutamyl)lysine in fibrin polymerized by factor XIII. Biochemistry, 1969, Volume: 8, Issue:3 Topics: Alkylating Agents; Alkylation; Autoanalysis; Blood Coagulation Factors; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cyanides; Edetic Acid; Factor XIII; Fibrin; Glutamates; Humans; Lysine; Methods; Peptides; Protease Inhibitors; Protein Hydrolysates	1969
Hybrid fibrin: proof of the intermolecular nature of - crosslinking units. Biochemical and biophysical research communications, 1971, Jul-02, Volume: 44, Issue:1 Topics: Animals; Binding Sites; Calcium Chloride; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Dialysis; Electrophoresis, Paper; Ethanol; Fibrin; Fibrinogen; Glutamates; Glycine; Humans; Lysine; Methods; Protein Binding; Sulfites; Thrombin; Trypsin; Urea	1971
- cross-linking sites in human and bovine fibrin. Biochemistry, 1971, Nov-23, Volume: 10, Issue:24 Topics: Acetates; Amino Acid Sequence; Amino Acids; Animals; Calcium; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Dansyl Compounds; Factor XIII; Fibrin; Glutamine; Glycine; Histidine; Humans; Lysine; Macromolecular Substances; Models, Biological; Peptides; Sulfites; Thermolysin; Thioglycolates; Trypsin	1971
Epsilon-(gamma glutamyl) lysine in fibrin: lack of crosslink formation in Factor 13 deficiency. Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:4 Topics: Blood Coagulation Disorders; Factor XIII; Fibrin; Glutamates; Humans; Lysine; Methods; Peptides	1971
Amino acid transport into human platelets and subsequent incorporation into protein. Thrombosis et diathesis haemorrhagica, 1970, Feb-28, Volume: 23, Issue:1 Topics: Amino Acids; Biological Transport; Blood Platelets; Blood Proteins; Carbon Isotopes; Cell Membrane; Cysteine; Fibrin; Fibrinogen; Glutamates; Humans; Leucine; Lysine; Microscopy, Electron; Mitochondria; Proline; Puromycin; Serine; Thrombin; Valine	1970
Studies of invertebrate fibrinogen. II. Transformation of lobster fibrinogen into fibrin. Biochemistry, 1971, Apr-13, Volume: 10, Issue:8 Topics: Acrylates; Alkylation; Animals; Carbon Isotopes; Crustacea; Dipeptides; Fibrin; Fibrinogen; Gels; Glutamates; Lysine; Microscopy, Electron; Nitriles	1971
The identification of isopeptide crosslinks in insoluble fibrin. Biochemical and biophysical research communications, 1968, Feb-26, Volume: 30, Issue:4 Topics: Carbon Isotopes; Chromatography; Dipeptides; Fibrin; Glutamates; Lysine; Peptides; Protein Hydrolysates; Transaminases	1968
The transpeptidase system which crosslinks fibrin by gamma-glutamyle-episilon-lysine bonds. Biochemical and biophysical research communications, 1968, Apr-19, Volume: 31, Issue:2 Topics: Amino Acids; Centrifugation, Density Gradient; Centrifugation, Zonal; Electrophoresis; Factor XIII; Fibrin; Glutamates; Lysine; Molecular Weight; Ultracentrifugation	1968
Nonenzymatic glycosylation reduces the susceptibility of fibrin to degradation by plasmin. Diabetes, 1983, Volume: 32, Issue:7 Topics: Binding Sites; Chemical Phenomena; Chemistry; Diabetes Mellitus; Fibrin; Fibrinogen; Fibrinolysin; Glucose; Humans; Hyperglycemia; In Vitro Techniques; Lysine; Protein Conformation; Time Factors	1983
A critical role of lysine residues in the stimulation of tissue plasminogen activator by denatured proteins and fibrin clots. Biochimica et biophysica acta, 1983, Mar-30, Volume: 743, Issue:3 Topics: Animals; Blood Coagulation; Cattle; Fibrin; Humans; Immunoglobulin G; Kinetics; Lysine; Macromolecular Substances; Molecular Weight; Plasminogen; Plasminogen Activators; Protein Binding; Protein Denaturation	1983
Secondary-site binding of Glu-plasmin, Lys-plasmin and miniplasmin to fibrin. The Biochemical journal, 1981, Sep-01, Volume: 197, Issue:3 Topics: alpha-2-Antiplasmin; Binding Sites; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinolysin; Glutamates; Humans; Lysine; Peptide Fragments; Plasminogen; Protein Binding; Tranexamic Acid	1981
The binding of glu- and lys-plasminogens to fibrin and their subsequent effects on fibrinolysis. Thrombosis research, 1980, Aug-01, Volume: 19, Issue:3 Topics: Adsorption; Binding Sites; Blood Coagulation; Cross-Linking Reagents; Fibrin; Fibrinolysis; Glutamates; Humans; Lysine; Plasminogen; Streptokinase	1980
Localization of a cross-link donor site in the alpha-chain of human fibrin. Thrombosis research, 1980, Sep-15, Volume: 19, Issue:6 Topics: Alanine; Amino Acid Sequence; Cross-Linking Reagents; Cyanogen Bromide; Cysteine; Fibrin; Fibrinogen; Lysine; Peptides; Threonine; Valine	1980
The binding of plasminogen to fibrin: evidence for plasminogen-bridging. Thrombosis research, 1982, Aug-01, Volume: 27, Issue:3 Topics: Binding Sites; Blood Coagulation; Chromatography, Gel; Dose-Response Relationship, Drug; Fibrin; Glutamine; Humans; Lysine; Molecular Weight; Plasminogen	1982
Fibrinolytic states in a patient with congenital deficiency of alpha 2-plasmin inhibitor. Blood, 1980, Volume: 55, Issue:3 Topics: alpha-2-Antiplasmin; Antigens; Chemical Phenomena; Chemistry; Fibrin; Fibrinogen; Fibrinolysis; Glutamates; Humans; Lysine; Plasminogen; Time Factors; Tranexamic Acid; Urokinase-Type Plasminogen Activator	1980
Alpha-Chain cross-linking in fibrin(ogen) Marburg. Blood, 1995, Aug-01, Volume: 86, Issue:3 Topics: Amino Acid Sequence; Blood Coagulation; Fibrin; Fibrinogens, Abnormal; Humans; In Vitro Techniques; Lysine; Molecular Sequence Data; Molecular Weight; Peptides; Structure-Activity Relationship; Transglutaminases	1995
Tissue-type plasminogen activator (tPA) interacts with urokinase-type plasminogen activator (uPA) via tPA's lysine binding site. An explanation of the poor fibrin affinity of recombinant tPA/uPA chimeric molecules. The Journal of biological chemistry, 1995, Apr-14, Volume: 270, Issue:15 Topics: Amino Acid Sequence; Animals; Binding Sites; Calorimetry, Differential Scanning; CHO Cells; Cricetinae; Fibrin; Fluorescence Polarization; Lysine; Molecular Sequence Data; Recombinant Fusion Proteins; Sequence Deletion; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	1995
The role of the lysyl binding site of tissue-type plasminogen activator in the interaction with a forming fibrin clot. The Journal of biological chemistry, 1995, May-26, Volume: 270, Issue:21 Topics: Amino Acid Sequence; Aminocaproates; Animals; Binding Sites; Binding, Competitive; Blood Coagulation; DNA Mutational Analysis; Fibrin; L Cells; Lysine; Mice; Models, Biological; Molecular Sequence Data; Point Mutation; Protein Binding; Recombinant Proteins; Sequence Deletion; Tissue Plasminogen Activator	1995
The structure of recombinant plasminogen kringle 1 and the fibrin binding site. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1994, Volume: 5, Issue:2 Topics: Amino Acid Sequence; Binding Sites; Crystallization; Fibrin; Kringles; Lysine; Molecular Sequence Data; Plasminogen; Protein Conformation; Recombinant Proteins	1994
Mechanism of the enhanced intrinsic activity of single-chain urokinase-type plasminogen activator during ongoing fibrinolysis. The Journal of biological chemistry, 1993, Sep-05, Volume: 268, Issue:25 Topics: Alanine; Binding Sites; Catalysis; Cell Line; Enzyme Activation; Fibrin; Fibrinolysis; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Plasminogen; Plasminogen Activator Inhibitor 1; Recombinant Proteins; Serine; Solutions; Urokinase-Type Plasminogen Activator	1993
Study of tissue-type plasminogen activator binding sites on fibrin using distinct fragments of fibrinogen. European journal of biochemistry, 1994, Feb-01, Volume: 219, Issue:3 Topics: Animals; Antibodies, Monoclonal; Binding Sites; Binding, Competitive; Carboxypeptidase B; Carboxypeptidases; Cyanogen Bromide; Fibrin; Fibrinogen; Fibrinolysin; Humans; Lysine; Mice; Radioligand Assay; Tissue Plasminogen Activator	1994
Kringle glycosylation in a modified human tissue plasminogen activator improves functional properties. Blood, 1993, Mar-01, Volume: 81, Issue:5 Topics: Base Sequence; Fibrin; Fibrinogen; Fibrinolysis; Glycosylation; Humans; Lysine; Molecular Sequence Data; Peptide Fragments; Plasminogen Activator Inhibitor 1; Structure-Activity Relationship; Tissue Plasminogen Activator	1993
Introduction of lysine and clot binding properties in the kringle one domain of tissue-type plasminogen activator. The Journal of biological chemistry, 1993, Sep-05, Volume: 268, Issue:25 Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cyanogen Bromide; Fibrin; Fibrinogen; Fibrinolysin; Lysine; Molecular Sequence Data; Peptide Fragments; Tissue Plasminogen Activator	1993
Fibrinogen Bern I: substitution gamma 337 Asn-->Lys is responsible for defective fibrin monomer polymerization. Blood, 1993, Oct-01, Volume: 82, Issue:7 Topics: Adult; Aged; Amino Acid Sequence; Asparagine; Base Sequence; DNA; DNA Primers; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Female; Fibrin; Fibrinogen; Fibrinogens, Abnormal; Fibrinopeptide A; Fibrinopeptide B; Genetic Variation; Humans; Kinetics; Lysine; Male; Molecular Sequence Data; Nuclear Family; Oligonucleotides, Antisense; Point Mutation; Polymerase Chain Reaction	1993
Identification of the alpha chain lysine donor sites involved in factor XIIIa fibrin cross-linking. The Journal of biological chemistry, 1996, Aug-09, Volume: 271, Issue:32 Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Fibrin; Humans; Lysine; Molecular Sequence Data; Transglutaminases	1996
Domain-domain interactions in hybrids of tissue-type plasminogen activator and urokinase-type plasminogen activator. Protein engineering, 1995, Volume: 8, Issue:12 Topics: Amino Acid Sequence; Aminocaproic Acid; Animals; Base Sequence; Binding Sites; CHO Cells; Chromatography, Affinity; Cloning, Molecular; Consensus Sequence; Cricetinae; DNA Primers; Electrophoresis, Polyacrylamide Gel; Fibrin; Kringles; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Engineering; Recombinant Proteins; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	1995
Lysis of surface-localized fibrin clots by adsorbed plasminogen in the presence of tissue plasminogen activator. Biomaterials, 1996, Volume: 17, Issue:1 Topics: Adsorption; Fibrin; Glass; Lysine; Plasminogen; Receptors, Cell Surface; Silicates; Surface Properties; Tissue Plasminogen Activator	1996
Converting tissue type plasminogen activator into a zymogen. Important role of Lys156. The Journal of biological chemistry, 1997, Jan-03, Volume: 272, Issue:1 Topics: Animals; COS Cells; Enzyme Activation; Enzyme Precursors; Fibrin; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Plasminogen Activator Inhibitor 1; Recombinant Proteins; Structure-Activity Relationship; Tissue Plasminogen Activator; Tyrosine	1997
A battery of monoclonal antibodies that induce unique conformations to evolve cryptic but constitutive functions of plasminogen. Journal of biochemistry, 1997, Volume: 121, Issue:2 Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Blotting, Western; Catalysis; Fibrin; Fibrinolysin; Humans; Kinetics; Kringles; Lysine; Mice; Peptide Fragments; Plasminogen; Protein Binding; Protein Conformation; Structure-Activity Relationship; Surface Properties; Urokinase-Type Plasminogen Activator	1997
Modification of apolipoprotein(a) lysine binding site reduces atherosclerosis in transgenic mice. The Journal of clinical investigation, 1997, Aug-01, Volume: 100, Issue:3 Topics: Animals; Aorta; Arteriosclerosis; Binding Sites; Fibrin; Lipoprotein(a); Lysine; Mice; Mice, Transgenic; Mutagenesis, Site-Directed	1997
Enhancement of plasminogen binding and fibrinolysis by chloropeptin I. Thrombosis research, 1997, Sep-15, Volume: 87, Issue:6 Topics: Anti-Bacterial Agents; Binding Sites; Chlorophenols; Fibrin; Fibrinolysin; Fibrinolysis; Humans; Kinetics; Lysine; Oligopeptides; Peptides, Cyclic; Plasma; Plasminogen; Protein Binding; Tissue Plasminogen Activator; Tumor Cells, Cultured	1997
Elimination of the Cys558-Cys566 bond in Lys78-plasminogen--effect on activation and fibrin interaction. European journal of biochemistry, 1998, Jan-15, Volume: 251, Issue:1-2 Topics: Animals; Cricetinae; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibrin; Fibrinolysin; Lysine; Plasminogen; Recombinant Proteins; Serine; Serine Endopeptidases; Streptokinase; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	1998
A study of the mechanism of inhibition of fibrinolysis by activated thrombin-activable fibrinolysis inhibitor. The Journal of biological chemistry, 1998, Oct-16, Volume: 273, Issue:42 Topics: Arginine; Carboxypeptidase B2; Carboxypeptidases; Enzyme Activation; Enzyme Precursors; Fibrin; Fibrinolysin; Fibrinolysis; Humans; Lysine; Peptide Fragments; Plasminogen; Plasminogen Activators	1998
Inactivation of active thrombin-activable fibrinolysis inhibitor takes place by a process that involves conformational instability rather than proteolytic cleavage. The Journal of biological chemistry, 2000, Apr-28, Volume: 275, Issue:17 Topics: Carboxypeptidase B2; Carboxypeptidases; Chromatography, High Pressure Liquid; Cloning, Molecular; Enzyme Activation; Fibrin; Fibrinolysis; Humans; Lysine; Mutation; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thrombin; Thrombomodulin; Time Factors	2000
Cross-linking of plasminogen activator inhibitor 2 and alpha 2-antiplasmin to fibrin(ogen). The Journal of biological chemistry, 2000, Aug-11, Volume: 275, Issue:32 Topics: alpha-2-Antiplasmin; Amino Acid Sequence; Binding Sites; Cross-Linking Reagents; Fibrin; Fibrinogen; Humans; Lysine; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Plasminogen Activator Inhibitor 2; Protein Conformation; Recombinant Proteins; Substrate Specificity; Transglutaminases; Trypsin	2000
Thrombin-activable fibrinolysis inhibitor attenuates (DD)E-mediated stimulation of plasminogen activation by reducing the affinity of (DD)E for tissue plasminogen activator. A potential mechanism for enhancing the fibrin specificity of tissue plasminogen The Journal of biological chemistry, 2000, Nov-24, Volume: 275, Issue:47 Topics: Amino Acid Chloromethyl Ketones; Arginine; Carboxypeptidase B; Carboxypeptidase B2; Carboxypeptidases; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Humans; Kinetics; Lysine; Models, Chemical; Tissue Plasminogen Activator	2000
Selective inhibition of inducible nitric oxide synthase enhances intraglomerular coagulation in chronic anti-Thy 1 nephritis. Kidney international, 2002, Volume: 61, Issue:3 Topics: Albuminuria; Animals; Blood Platelets; Blood Pressure; Chronic Disease; Enzyme Inhibitors; Fibrin; Isoantibodies; Kidney Glomerulus; Lysine; Nephritis; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred Lew; Thrombosis	2002
A novel antithrombotic role for high molecular weight kininogen as inhibitor of plasminogen activator inhibitor-1 function. The Journal of biological chemistry, 2002, Sep-06, Volume: 277, Issue:36 Topics: Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Extracellular Matrix; Fibrin; Fibrinolysin; Fibrinolytic Agents; Glycine; Humans; Kinetics; Kininogens; Lysine; Plasminogen Activator Inhibitor 1; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Signal Transduction; Umbilical Veins; Vitronectin	2002
Angiostatin binds to tyrosine kinase substrate annexin II through the lysine-binding domain in endothelial cells. Microvascular research, 2002, Volume: 64, Issue:3 Topics: Angiostatins; Animals; Annexin A2; Cattle; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Extracellular Matrix; Fibrin; Humans; Immunoblotting; Kinetics; Ligands; Lysine; Microcirculation; Neovascularization, Physiologic; Peptide Fragments; Peptides; Plasminogen; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Signal Transduction	2002
Identification and characterization of novel lysine-independent apolipoprotein(a)-binding sites in fibrin(ogen) alphaC-domains. The Journal of biological chemistry, 2003, Sep-26, Volume: 278, Issue:39 Topics: Apolipoproteins; Apoprotein(a); Binding Sites; Binding, Competitive; Fibrin; Fibrinogen; Humans; Lipoprotein(a); Lysine; Peptide Fragments; Plasminogen; Tissue Plasminogen Activator	2003
A method of reducing the fibrinolytic activity of endometrium cells in plasma clot tissue culture. Experientia, 1959, Apr-15, Volume: 15, Issue:4 Topics: Endometrium; Female; Fibrin; Humans; Lysine; Plasma; Thrombolytic Therapy; Tissue Culture Techniques	1959
The action of poly-lysine on the conversion of fibrinogen into fibrin by coagulase thrombin. The Biochemical journal, 1955, Volume: 59, Issue:1 Topics: Blood Coagulation; Coagulase; Fibrin; Fibrinogen; Humans; Lysine; Thrombin	1955
Baboon lipoprotein(a) binds very weakly to lysine-agarose and fibrin despite the presence of a strong lysine-binding site in apolipoprotein(a) kringle IV type 10. Biochemistry, 2005, Jan-18, Volume: 44, Issue:2 Topics: Amino Acid Sequence; Animals; Apolipoproteins; Apoprotein(a); Arginine; Base Sequence; Binding Sites; Fibrin; Gene Expression Regulation; Humans; Kringles; Lipoprotein(a); Liver; Lysine; Molecular Sequence Data; Papio; Polymorphism, Genetic; Protein Binding; Recombinant Proteins; Sepharose; Tryptophan	2005
Selective inducible nitric oxide synthase inhibition attenuates organ dysfunction and elevated endothelin levels in LPS-induced DIC model rats. Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:5 Topics: Alanine Transaminase; Animals; Arteries; Blood Pressure; Creatinine; Disseminated Intravascular Coagulation; Endothelins; Endothelium, Vascular; Enzyme Inhibitors; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Kidney; Lipopolysaccharides; Liver; Lysine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plasminogen Activator Inhibitor 1; Pressure; Rats; Rats, Wistar; Time Factors	2005
Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis. The FEBS journal, 2005, Volume: 272, Issue:13 Topics: Animals; Antibodies, Monoclonal; Antifibrinolytic Agents; Apoptosis; Binding Sites; Cell Adhesion; CHO Cells; Cricetinae; Fibrin; Fibrinolysin; Fibrinolysis; Glutamic Acid; Humans; Kringles; Lysine; Peptide Fragments; Plasminogen; Protein Binding; Protein Conformation; Recombinant Proteins	2005
Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating fibrinolysis. The FEBS journal, 2006, Volume: 273, Issue:4 Topics: Amino Acid Sequence; Animals; Blood Coagulation; Carboxypeptidase B2; Cell Line; Down-Regulation; Enzyme Activation; Enzyme Stability; Fibrin; Fibrinolysis; Hot Temperature; Humans; Lysine; Molecular Sequence Data; Mutagenesis; Point Mutation; Protein Denaturation; Protein Precursors; Sequence Alignment	2006
Factor XIIIa mediated attachment of S. aureus fibronectin-binding protein A (FnbA) to fibrin: identification of Gln103 as a major cross-linking site. Biochemistry, 2006, Feb-14, Volume: 45, Issue:6 Topics: Adhesins, Bacterial; Base Sequence; Binding Sites; Catalysis; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Factor XIIIa; Fibrin; Glutamine; Leucine; Lysine; Proline; Staphylococcus aureus; Time Factors; Urea	2006
Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia. Biochemistry, 2006, Feb-28, Volume: 45, Issue:8 Topics: Amino Acid Sequence; Blood Coagulation; Dose-Response Relationship, Drug; Fibrin; Fibrinogen; Fibrinolysis; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Models, Biological; Molecular Sequence Data; Plasminogen; Protein Binding; Radiation-Protective Agents; Structure-Activity Relationship; Thrombosis; Tissue Plasminogen Activator	2006
Functional characterization of fibrinogen Bicêtre II: a gamma 308 Asn-->Lys mutation located near the fibrin D:D interaction sites. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2006, Volume: 17, Issue:3 Topics: Adult; Asparagine; Blood Coagulation; Coagulation Protein Disorders; Factor XIII; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogens, Abnormal; Fibrinolysis; Humans; Lysine; Male; Microscopy, Electron, Scanning; Models, Molecular; Mutation, Missense; Reference Values	2006
Interaction of fibrin(ogen) with apolipoprotein(a): further characterization and identification of a novel lysine-dependent apolipoprotein(a)-binding site within the gamma chain 287-411 region. Biochemistry, 2006, Sep-05, Volume: 45, Issue:35 Topics: Apolipoproteins; Binding Sites; Binding, Competitive; Fibrin; Fibrinogen; Kinetics; Lysine; Models, Molecular; Peptide Fragments; Peptide Hydrolases; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship	2006
Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini. Biochemistry, 2007, Sep-04, Volume: 46, Issue:35 Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Chickens; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinolysin; Fibrinolysis; Glycine; Humans; Lampreys; Lysine; Models, Molecular; Molecular Sequence Data; Oligopeptides; Protein Binding; Protein Conformation; Species Specificity; Tissue Plasminogen Activator; Tyrosine	2007
Antiangiogenic kringles derived from human plasminogen and apolipoprotein(a) inhibit fibrinolysis through a mechanism that requires a functional lysine-binding site. Biological chemistry, 2011, Volume: 392, Issue:4 Topics: Amino Acid Sequence; Angiogenesis Inhibitors; Angiostatins; Apolipoproteins A; Binding Sites; Dose-Response Relationship, Drug; Fibrin; Fibrinogen; Fibrinolysis; Humans; Kringles; Lysine; Molecular Sequence Data; Peptide Fragments; Plasminogen; Thrombin; Tissue Plasminogen Activator	2011
Identification of respective lysine donor and glutamine acceptor sites involved in factor XIIIa-catalyzed fibrin α chain cross-linking. The Journal of biological chemistry, 2011, Dec-30, Volume: 286, Issue:52 Topics: Binding Sites; Factor XIIIa; Fibrin; Glutamine; Humans; Lysine; Peptides; Structure-Activity Relationship	2011
Increased zymogen activity of thrombin-activatable fibrinolysis inhibitor prolongs clot lysis. Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:6 Topics: Antibodies, Catalytic; Aspartic Acid; Carboxypeptidase B2; Catalysis; Enzyme Activation; Enzyme Stability; Epitope Mapping; Epitopes; Fibrin; Fibrinolysis; Humans; Hydrolysis; Kinetics; Lysine; Models, Molecular; Protein Conformation; Recombinant Proteins; Threonine	2012
Regulation of fibrinolysis by C-terminal lysines operates through plasminogen and plasmin but not tissue-type plasminogen activator. Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:11 Topics: Binding Sites; Carboxypeptidase B; Fibrin; Fibrinolysin; Fibrinolysis; Humans; Kinetics; Kringles; Lysine; Plasminogen; Protein Binding; Protein Structure, Tertiary; Tissue Plasminogen Activator; Tranexamic Acid; Urokinase-Type Plasminogen Activator	2012
Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression. Nature communications, 2014, Aug-06, Volume: 5 Topics: Animals; Biosensing Techniques; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA Methylation; Female; Fibrin; Fluorescence Resonance Energy Transfer; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Integrin beta1; Lysine; Melanoma; Melanoma, Experimental; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Promoter Regions, Genetic; RNA, Small Interfering; Skin Neoplasms; SOXB1 Transcription Factors; Time Factors	2014
Polyphosphate colocalizes with factor XII on platelet-bound fibrin and augments its plasminogen activator activity. Blood, 2016, 12-15, Volume: 128, Issue:24 Topics: Blood Platelets; Complement C1 Inhibitor Protein; Factor XII; Fibrin; Glutamic Acid; HeLa Cells; Humans; Lysine; Plasminogen; Polyphosphates; Proteins	2016
Mechanism of plasmin generation by S100A10. Thrombosis and haemostasis, 2017, 06-02, Volume: 117, Issue:6 Topics: Annexin A2; Fibrin; Fibrinolysin; Humans; Kringles; Lysine; Mutagenesis, Site-Directed; Plasminogen; Protein Binding; Protein Engineering; Receptors, Cell Surface; S100 Proteins; Tissue Plasminogen Activator	2017
Mass spectrometry-based molecular mapping of native FXIIIa cross-links in insoluble fibrin clots. The Journal of biological chemistry, 2019, 05-31, Volume: 294, Issue:22 Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Factor XIIIa; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Lysine; Mass Spectrometry; Peptide Mapping; Peptides; Thrombosis	2019
Insight into the mechanism of myosin-fibrin gelation induced by non-disulfide covalent cross-linking. Food research international (Ottawa, Ont.), 2022, Volume: 156 Topics: Fibrin; Fibrinogen; Gels; Lysine; Myosin Heavy Chains; Myosins; Transglutaminases	2022
Altered fibrinogen γ-chain cross-linking in mutant fibrinogen-γ Journal of thrombosis and haemostasis : JTH, 2023, Volume: 21, Issue:8 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury, Chronic; Fibrin; Fibrinogen; Integrins; Lysine; Mice	2023