lysine has been researched along with eflornithine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (41.38) | 18.7374 |
| 1990's | 10 (34.48) | 18.2507 |
| 2000's | 5 (17.24) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Coffino, P; Tsirka, S | 1 |
| Ackermann, B; Bey, P; Lu, L; Pegg, AE; Poulin, R | 1 |
| Folk, JE; Hershey, JW; Park, MH; Smit-McBride, Z; Wolff, EC | 1 |
| Blachier, F; Leclercq-Meyer, V; Malaisse, WJ; Marchand, J; Mathias, PC; Sener, A; Woussen-Colle, MC | 1 |
| Park, MH | 2 |
| Bacchi, CJ; Bitonti, AJ; McCann, PP; Sjoerdsma, A | 1 |
| Chang, ZF; Chen, KY | 1 |
| Bernhardt, A; Gerner, EW; Mamont, PS; Siat, M | 1 |
| Gaget, C; Heintzelmann, B; Wagner, J; Wolf, E | 1 |
| Park, MH; Wolff, EC | 1 |
| Alitalo, K; Hölttä, E; Jänne, OA; Knuutila, S; Pohjanpelto, P | 1 |
| Bey, P; McCann, PP; Pösö, H; Sjoerdsma, A; Tanskanen, R | 1 |
| Persson, L | 1 |
| Erwin, BG; Pegg, AE | 1 |
| Byers, TL; Coward, JK; Lakanen, JR; Pegg, AE | 1 |
| Byus, CV; Fukumoto, GH; Hawel, L; Tjandrawinata, RR | 1 |
| Kahana, C; Tobias, KE | 1 |
| Chen, KY; Chen, ZP | 2 |
| Fiser, SM; Gerner, EW; Payne, CM; Tome, ME | 1 |
| Kamio, Y; Muramoto, K; Onoda, M; Sugiyama, T; Takatsuka, Y; Tomita, T | 1 |
| Burns, MR; Cai, F; Carlson, CL; Devens, BH; O'Day, CL; Vanderwerf, SM; Webb, HK; Weeks, RS | 1 |
| Burns, MR; Cai, F; Carlson, CL; Graminski, GF; Vanderwerf, SM; Webb, HK; Weeks, RS; Ziemer, JR | 1 |
| Igarashi, K; Kashiwagi, K; Murozumi, K; Nishimura, K; Park, MH; Shirahata, A | 1 |
| Alhonen, L; Cerrada-Gimenez, M; Grigorenko, N; Hyvönen, MT; Jänne, J; Keinänen, TA; Khomutov, AR; Sinervirta, R; Vepsäläinen, J | 1 |
| Burns, MR; Chen, Y; Graminski, GF; O'Brien, TG; Weeks, RS | 1 |
| Alhonen, L; Hyvönen, MT; Keinänen, TA; Khomutov, AR; Khomutov, M; Kochetkov, SN; Petit, M; Vepsäläinen, J; Weisell, J | 1 |
| Cruz-Pulido, YE; Mounce, BC | 1 |
1 review(s) available for lysine and eflornithine
| Article | Year |
|---|---|
Good cop, bad cop: Polyamines play both sides in host immunity and viral replication.
Topics: Adaptive Immunity; Antineoplastic Agents; Antiviral Agents; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Host Microbial Interactions; Humans; Lysine; Polyamines; Protein Processing, Post-Translational; Virus Diseases; Virus Replication; Viruses | 2023 |
28 other study(ies) available for lysine and eflornithine
| Article | Year |
|---|---|
Dominant negative mutants of ornithine decarboxylase.
Topics: Amino Acid Sequence; Animals; Arginine; Eflornithine; Gene Expression; Genes; Genes, Dominant; Kinetics; Lysine; Mice; Mutagenesis, Site-Directed; Ornithine Decarboxylase; Plasmids; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping | 1992 |
Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Chromatography, High Pressure Liquid; Coenzymes; Eflornithine; Escherichia coli; Lysine; Mice; Molecular Sequence Data; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pyridoxal Phosphate; Recombinant Proteins; Spectrometry, Mass, Fast Atom Bombardment; Trypsin | 1992 |
Comparison of the activities of variant forms of eIF-4D. The requirement for hypusine or deoxyhypusine.
Topics: Animals; Cadaverine; Cells, Cultured; Chromatography, Ion Exchange; Cricetinae; Eflornithine; Escherichia coli; Eukaryotic Translation Initiation Factor 5A; Humans; Lysine; Molecular Structure; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Periodic Acid; Puromycin; RNA-Binding Proteins; Spermidine; Substrate Specificity | 1991 |
Stimulus-secretion coupling of arginine-induced insulin release. Functional response of islets to L-arginine and L-ornithine.
Topics: Animals; Arginine; Calcium; Dose-Response Relationship, Drug; Eflornithine; Glucose; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Lysine; Ornithine; Oxidation-Reduction; Polyamines; Rats | 1989 |
The essential role of hypusine in eukaryotic translation initiation factor 4D (eIF-4D). Purification of eIF-4D and its precursors and comparison of their activities.
Topics: Animals; Cell Line; Cricetinae; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Isoelectric Point; Lysine; Molecular Weight; Peptide Initiation Factors; Protein Precursors; Protein Processing, Post-Translational; Putrescine; RNA-Binding Proteins; Spermidine; Structure-Activity Relationship | 1989 |
Uptake of alpha-difluoromethylornithine by Trypanosoma brucei brucei.
Topics: Animals; Arginine; Biological Transport; Diffusion; Eflornithine; Lysine; Ornithine; Temperature; Trypanosoma brucei brucei | 1986 |
Age dependency of the metabolic conversion of polyamines into amino acids in IMR-90 human embryonic lung diploid fibroblasts.
Topics: Amino Acids; Cell Line; Cell Survival; Diploidy; Eflornithine; Enzyme Induction; Fibroblasts; Humans; Lysine; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Processing, Post-Translational; Putrescine | 1986 |
Post-translational modification of the protein-synthesis initiation factor eIF-4D by spermidine in rat hepatoma cells.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Liver Neoplasms, Experimental; Lysine; Neoplasm Proteins; Peptide Initiation Factors; Protein Binding; Protein Biosynthesis; Rats; RNA-Binding Proteins; Spermidine; Spermine | 1986 |
Regulation of biosynthesis of hypusine in Chinese hamster ovary cells. Evidence for eIF-4D precursor polypeptides.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Cycloheximide; Eflornithine; Female; Fibroblasts; Gene Expression Regulation; Lysine; Ovary; Protein Biosynthesis; Protein Processing, Post-Translational; Spermidine | 1987 |
Resolution of the enantiomers of various alpha-substituted ornithine and lysine analogs by high-performance liquid chromatography with chiral eluant and by gas chromatography on Chirasil-Val.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Copper; Eflornithine; Indicators and Reagents; Lysine; Organic Chemicals; Ornithine; Ornithine Decarboxylase Inhibitors; Stereoisomerism | 1987 |
Cell-free synthesis of deoxyhypusine. Separation of protein substrate and enzyme and identification of 1,3-diaminopropane as a product of spermidine cleavage.
Topics: Animals; Cell Line; Cell-Free System; Chromatography, Ion Exchange; Cricetinae; Diamines; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Lysine; NAD; Peptide Initiation Factors; RNA-Binding Proteins; Spermidine | 1988 |
Amplification of ornithine decarboxylase gene in response to polyamine deprivation in Chinese hamster ovary cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Cadaverine; Cell Line; Cricetinae; Cricetulus; Eflornithine; Electrophoresis, Polyacrylamide Gel; Female; Gene Amplification; Karyotyping; Kinetics; Lysine; Ornithine; Ornithine Decarboxylase; Ovary; Plasmids; Polyamines; RNA, Messenger; Spermine | 1985 |
Inhibition of growth of Mycoplasma dispar by DL-alpha-difluoromethyllsine, a selective irreversible inhibitor of lysine decarboxylase, and reversal by cadaverine (1,5-diaminopentane).
Topics: Arginine; Cadaverine; Carboxy-Lyases; Cell Division; Diamines; Eflornithine; Lysine; Mycoplasma; Ornithine | 1984 |
Decarboxylation of ornithine and lysine by ornithine decarboxylase from kidneys of testosterone treated mice.
Topics: Animals; Cadaverine; Carboxy-Lyases; Eflornithine; Kidney; Lysine; Male; Mice; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Testosterone | 1981 |
Uptake of alpha-difluoromethylornithine by mouse fibroblasts.
Topics: Animals; Cells, Cultured; Eflornithine; Fibroblasts; Lysine; Mice; Ornithine | 1982 |
The role of hypusine depletion in cytostasis induced by S-adenosyl-L-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Deoxyadenosines; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Leukemia L1210; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; RNA-Binding Proteins; Spermidine; Spermine; Substrate Specificity; Tumor Cells, Cultured | 1994 |
Biosynthesis and selective export of 1,5-diaminopentane (cadaverine) in mycoplasma-free cultured mammalian cells.
Topics: Amino Acids; Animals; Biological Transport; Cadaverine; Carcinoma, Hepatocellular; Cell Line; Culture Media; Eflornithine; Insulin; Kinetics; Lipopolysaccharides; Lysine; Mice; Mycoplasma; Ornithine; Putrescine; Rats; Spectrometry, Mass, Fast Atom Bombardment; Tumor Cells, Cultured | 1994 |
Intersubunit location of the active site of mammalian ornithine decarboxylase as determined by hybridization of site-directed mutants.
Topics: Alanine; Animals; Base Sequence; Binding Sites; Cysteine; Eflornithine; Lysine; Macromolecular Substances; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Ornithine Decarboxylase; Pyridoxal Phosphate; Structure-Activity Relationship | 1993 |
Dramatic attenuation of hypusine formation on eukaryotic initiation factor 5A during senescence of IMR-90 human diploid fibroblasts.
Topics: Antineoplastic Agents; Cells, Cultured; Cellular Senescence; Diploidy; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Lung; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; RNA-Binding Proteins; Substrate Specificity | 1997 |
Marked elevation of hypusine formation activity on eukaryotic initiation factor 5A in v-HA-RAS transformed mouse NIH3T3 cells.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Gene Expression; Lysine; Mice; Oncogene Protein p21(ras); Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; RNA-Binding Proteins; Spermidine | 1997 |
Excess putrescine accumulation inhibits the formation of modified eukaryotic initiation factor 5A (eIF-5A) and induces apoptosis.
Topics: Animals; Apoptosis; Cell Division; Diamines; Eflornithine; Enzyme Inhibitors; Eukaryotic Translation Initiation Factor 5A; Lysine; Microscopy, Electron; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Peptide Initiation Factors; Polyamines; Protein Processing, Post-Translational; Putrescine; Rats; RNA-Binding Proteins; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Novel characteristics of Selenomonas ruminantium lysine decarboxylase capable of decarboxylating both L-lysine and L-ornithine.
Topics: Amino Acid Sequence; Bacterial Proteins; Carboxy-Lyases; Eflornithine; Enzyme Inhibitors; Kinetics; Lysine; Molecular Sequence Data; Ornithine; Selenomonas; Substrate Specificity | 1999 |
Novel lysine-spermine conjugate inhibits polyamine transport and inhibits cell growth when given with DFMO.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Division; Eflornithine; Female; Humans; Indicators and Reagents; Kinetics; Lysine; Male; Melanoma; Mice; Mice, Nude; Molecular Structure; Polyamines; Prostatic Neoplasms; Spermidine; Spermine; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2000 |
Amino acid/spermine conjugates: polyamine amides as potent spermidine uptake inhibitors.
Topics: Amino Acids; Antineoplastic Agents; Biological Transport; Drug Interactions; Drug Screening Assays, Antitumor; Eflornithine; Humans; Lysine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured | 2001 |
Independent roles of eIF5A and polyamines in cell proliferation.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cyclohexylamines; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Half-Life; Humans; Lysine; Mice; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Polyamines; Putrescine; Rats; RNA-Binding Proteins; Spermine | 2005 |
Role of hypusinated eukaryotic translation initiation factor 5A in polyamine depletion-induced cytostasis.
Topics: alpha-Amylases; Animals; Animals, Genetically Modified; Cell Proliferation; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Humans; Kinetics; Lysine; Models, Biological; Pancreatitis; Peptide Initiation Factors; Polyamines; Rats; Recombinant Proteins; RNA-Binding Proteins; Spermidine; Stereoisomerism | 2007 |
Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Eflornithine; Lysine; Mice; Mice, Transgenic; Neoplasm Transplantation; Ornithine Decarboxylase; Polyamines; Skin Neoplasms; Spermine; Structure-Activity Relationship; Transplantation, Heterologous | 2009 |
Enantiomers of 3-methylspermidine selectively modulate deoxyhypusine synthesis and reveal important determinants for spermidine transport.
Topics: Biological Transport; Cell Line, Tumor; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Gene Expression; Humans; Lysine; Male; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Processing, Post-Translational; RNA-Binding Proteins; Spermidine; Stereoisomerism; Substrate Specificity | 2015 |