Page last updated: 2024-08-17

lysine and decitabine

lysine has been researched along with decitabine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (50.00)29.6817
2010's8 (40.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Ceman, S; Coffee, B; Reines, D; Warren, ST; Zhang, F1
Gonzales, FA; Jones, PA; Liang, G; Lin, JC; Nguyen, CT; Velicescu, M; Weisenberger, DJ1
Issa, JP; Kondo, Y; Shen, L1
Higashimoto, K; Joh, K; Kudo, S; Matsukura, S; Matsuo, S; Mukai, T; Nakagawachi, T; Soejima, H; Urano, T; Zhao, W1
Choi, EJ; Kim, JS; Kim, YH; Seo, JH; Whang, YM; Yoo, YD1
Chen, H; Costa, M; Ke, Q; Kluz, T; Yan, Y1
Huang, TH; Liu, JC; Plass, C; Potter, D; Smith, LT; Wang, SH; Wu, J; Wu, YZ1
Li, Z; Yang, N1
Chen, Y; Domann, FE; Hitchler, MJ; Weigel, RJ; Woodfield, GW1
Dai, DQ; Meng, CF; Peng, G; Zhu, XJ1
Kimmins, S; Lambrot, R1
Cho, S; Kang, YK; Lee, D; Park, JS; Shin, ST1
Godsey, S; Oyer, JA; Turker, MS; Yates, PA1
Au, SL; Ko, FC; Ng, IO; Ng, YL; Wong, CC; Wong, CM1
Cavalli, LR; da Costa Prando, E; Rainho, CA1
Chen, LH; Cheng, LY; Cherng, CG; Kao, GS; Su, CC; Tzeng, WY; Wang, CY; Yu, L1
Chen, PW; Li, H; Mellon, J; Niederkorn, JY; Sadegh, L1
Bachmann, M; Mühl, H; Pfeilschifter, J1
Allis, CD; Chen, H; Chen, X; Lu, C; Majewski, J; Rajagopalan, KN; Weinberg, DN1
Caron, M; Djibo, R; Huot, M; Najmanovich, R; Raynal, NJM; Richer, C; Sinnett, D; St-Onge, P1

Other Studies

20 other study(ies) available for lysine and decitabine

ArticleYear
Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome.
    American journal of human genetics, 2002, Volume: 71, Issue:4

    Topics: Acetylation; Alleles; Azacitidine; Decitabine; DNA Methylation; Fragile X Mental Retardation Protein; Fragile X Syndrome; Heterochromatin; Histones; Humans; Lysine; Nerve Tissue Proteins; RNA-Binding Proteins; Transcriptional Activation; Trinucleotide Repeats; Tumor Cells, Cultured

2002
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.
    Cancer research, 2002, Nov-15, Volume: 62, Issue:22

    Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Culture Techniques; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Gene Silencing; Histones; Humans; Lysine; Methylation; Precipitin Tests; Tumor Cells, Cultured; Tumor Suppressor Protein p14ARF; Urinary Bladder Neoplasms

2002
Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.
    Molecular and cellular biology, 2003, Volume: 23, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Carrier Proteins; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Methylation; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Precipitin Tests; Promoter Regions, Genetic; Tumor Cells, Cultured

2003
The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island.
    Journal of biochemistry, 2005, Volume: 137, Issue:3

    Topics: Azacitidine; Cell Line, Tumor; Chromosomal Proteins, Non-Histone; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Gene Expression; Gene Silencing; Histones; Humans; Hydroxamic Acids; Lysine; Methyl-CpG-Binding Protein 2; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins; Transcription Factors

2005
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:5

    Topics: Acetylation; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin

2005
Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing.
    Molecular and cellular biology, 2006, Volume: 26, Issue:10

    Topics: Animals; Azacitidine; Blotting, Western; Carcinoma; Cell Line; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epigenesis, Genetic; Fibroblasts; Gene Silencing; Histones; Humans; Kinetics; Lung Neoplasms; Lysine; Methyltransferases; Mice; Nickel; Trace Elements; Transgenes

2006
Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing.
    BMC genomics, 2007, May-24, Volume: 8

    Topics: Acetylation; Animals; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation; Gene Silencing; Histones; Hydroxamic Acids; Leukemia L1210; Lysine; Methylation; Mice; Mice, Inbred DBA; Oligonucleotide Array Sequence Analysis; Protein Processing, Post-Translational

2007
[5-aza-2'-deoxycytidine induces changes of histone H3-lysine 9 methylation in bladder tumor cells].
    Zhonghua yi xue za zhi, 2008, Aug-19, Volume: 88, Issue:32

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Survival; Core Binding Factor Alpha 3 Subunit; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Histones; Humans; Lysine; Methylation; Promoter Regions, Genetic; Time Factors; Urinary Bladder Neoplasms

2008
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-01, Volume: 15, Issue:11

    Topics: Acetylation; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-2

2009
Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells.
    Oncology reports, 2009, Volume: 22, Issue:5

    Topics: Acetylation; Azacitidine; Blotting, Western; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Enzyme Inhibitors; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Immunoprecipitation; Lysine; Polymerase Chain Reaction; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Cells, Cultured

2009
Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines.
    International journal of andrology, 2011, Volume: 34, Issue:2

    Topics: Azacitidine; Decitabine; Gene Silencing; Histones; Humans; Lysine; Male; Methylation; Octamer Transcription Factor-3; Proto-Oncogene Mas; Testicular Neoplasms; Tumor Suppressor Proteins

2011
Active loss of DNA methylation in two-cell stage goat embryos.
    The International journal of developmental biology, 2010, Volume: 54, Issue:8-9

    Topics: 5-Methylcytosine; Animals; Azacitidine; Decitabine; DNA; DNA Methylation; DNA Modification Methylases; Embryo, Mammalian; Enzyme Inhibitors; Female; Goats; Histones; Immunohistochemistry; Lysine; Male; Methylation; Zygote

2010
Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation.
    Mutation research, 2011, Jan-10, Volume: 706, Issue:1-2

    Topics: Adenine Phosphoribosyltransferase; Animals; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Lysine; Methylation; Mice; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Time Factors

2011
Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery.
    PloS one, 2011, Feb-08, Volume: 6, Issue:2

    Topics: Azacitidine; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genetic Loci; GTPase-Activating Proteins; HCT116 Cells; HeLa Cells; Histones; Humans; Lysine; Stochastic Processes; Transcription, Genetic; Tumor Suppressor Proteins

2011
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines.
    Epigenetics, 2011, Volume: 6, Issue:12

    Topics: Acetylation; Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromosomes, Human, Pair 3; Decitabine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; Lysine; Multigene Family; Promoter Regions, Genetic; Tumor Suppressor Proteins

2011
Neonatal isolation decreases cued fear conditioning and frontal cortical histone 3 lysine 9 methylation in adult female rats.
    European journal of pharmacology, 2012, Dec-15, Volume: 697, Issue:1-3

    Topics: Acoustic Stimulation; Age Factors; Animals; Animals, Newborn; Azacitidine; Behavior, Animal; Cerebral Cortex; Conditioning, Psychological; Corticosterone; Cues; Decitabine; DNA Modification Methylases; Dose-Response Relationship, Drug; Down-Regulation; Estradiol; Fear; Female; Histone Deacetylase Inhibitors; Histones; Light; Lysine; Maternal Deprivation; Methylation; Photic Stimulation; Rats; Rats, Sprague-Dawley; Reflex, Startle; Stress, Psychological; Valproic Acid

2012
Epigenetic regulation of CXCR4 expression by the ocular microenvironment.
    Investigative ophthalmology & visual science, 2013, Jan-09, Volume: 54, Issue:1

    Topics: Animals; Anterior Chamber; Antimetabolites, Antineoplastic; Azacitidine; Cecum; Cell Line, Tumor; Decitabine; Down-Regulation; Epigenesis, Genetic; Flow Cytometry; Gene Expression; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Injections; Injections, Subcutaneous; Lysine; Methylation; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Promoter Regions, Genetic; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; Spleen; Up-Regulation

2013
Epigenetic regulation by CpG methylation splits strong from retarded IFNγ-induced IL-18BP in epithelial versus monocytic cells.
    Biochimica et biophysica acta. Gene regulatory mechanisms, 2018, Volume: 1861, Issue:3

    Topics: Acetylation; Azacitidine; Cell Line; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Epithelial Cells; Histones; Humans; Intercellular Signaling Peptides and Proteins; Interferon-gamma; Lysine; Methyl-CpG-Binding Protein 2; Monocytes; Promoter Regions, Genetic; Protein Binding; RNA Polymerase II; Transcription Initiation Site; Transcription, Genetic

2018
Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-02, Volume: 118, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinogenesis; Cell Line; Chromatin; CRISPR-Cas Systems; Cytarabine; Decitabine; Epigenesis, Genetic; Gene Editing; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mesenchymal Stem Cells; Methylation; Mice; Mutation; Neoplasm Proteins; Neoplasms; Phenotype; Protein Isoforms; Protein Processing, Post-Translational; Repressor Proteins; Transcriptome

2021
Repurposing proscillaridin A in combination with decitabine against embryonal rhabdomyosarcoma RD cells.
    Cancer chemotherapy and pharmacology, 2021, Volume: 88, Issue:5

    Topics: Acetylation; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Self Renewal; Decitabine; Drug Repositioning; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Neoplasm Proteins; Promoter Regions, Genetic; Proscillaridin; Proto-Oncogene Proteins c-myc; Rhabdomyosarcoma, Embryonal

2021