lysine has been researched along with cysteine in 894 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 306 (34.23) | 18.7374 |
1990's | 144 (16.11) | 18.2507 |
2000's | 219 (24.50) | 29.6817 |
2010's | 157 (17.56) | 24.3611 |
2020's | 68 (7.61) | 2.80 |
Authors | Studies |
---|---|
Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
Audic, N; Ermolenko, L; Franck, G; Garcia-Alvarez, MC; Martin, MT; Nhiri, N; Potier, P; Sasaki, NA; Wang, Q | 1 |
Brown, JP; Hartman, FC | 1 |
Conti, SF; LaMarre, AG; Straley, SC | 1 |
Kim, CY; Sternberg, M | 1 |
Bartelt, DC; Greene, LJ | 2 |
Demain, AL; Friedrich, CG | 1 |
Boreisha, I; Robbins, KC; Summaria, L; Wohl, RC | 1 |
Estes, MK; Pagano, JS; Pett, DM | 1 |
Chibata, I; Kisumi, M; Komatsubara, S | 1 |
Gruen, LC | 1 |
Beckerich, JM; Heslot, H; Lambert, M | 1 |
Kiltz, HH; Kolkenbrock, H; Trommer, WE | 1 |
Kajiyama, KI; Nakayama, F; Sakamoto, M | 1 |
Hartman, FC; Schloss, JV; Stringer, CD | 1 |
Bergeron, M; Craan, AG | 1 |
Finlay, TH; Johnson, AJ; Marcus, DL | 1 |
Miyahara, T; Murai, A; Shiozawa, S | 1 |
Cole, DJ; Lewis, D | 1 |
Giartosio, A; Riva, F; Turano, C | 1 |
Friebel, K; Kiltz, HH; Kolkenbrock, HJ; Trommer, WE | 1 |
Ahlers, J; Günther, T | 1 |
Halsall, DM | 1 |
Ellory, JC; Tucker, EM; Young, JD | 2 |
Muller, LD; Rodriguez, D | 1 |
Chin, CC; Wold, F | 1 |
Burroughs, W; Mertens, DR; Nelson, DK | 1 |
Bayer, E; Hemmasi, B | 1 |
Guadalix, FJ; Ruiz, MC | 1 |
Crichton, RR; Wetz, K | 1 |
Guggi, A; Periotto, V; Rocchi, R; Tomatis, R | 1 |
Thevenet, NJ; Vandecasteele, JP | 1 |
Heremans, JF; Moussebois, CH; Osinski, P; Rennerts, W | 1 |
Mogil'naia, GM; Shubich, MG | 1 |
Blarzino, C; Coccia, R; De Marco, C; Foppoli, C; Pensa, B | 1 |
Ellis, J; Rosen, BP; Steffes, C; Wu, J | 1 |
Kirsch, JF; Toney, MD | 1 |
Brewer, HB; Lohse, P; Rader, DJ | 1 |
Chevallier, MR; Horák, J; Kotyk, A; Sychrová, H | 1 |
Baleux, F; Dubois, P | 1 |
Dallocchio, F; Hanau, S; Rippa, M | 1 |
Katiyar, SS; Sheikh, S | 4 |
Brand, L; James, E; Stites, W; Wu, PG | 1 |
Anders, MW; Fitzsimmons, ME; Harris, JW | 1 |
Jones, ME; Smiley, JA | 1 |
Hara, H; Ihara, I; Inoue, H; Nakamura, T; Sakai, H; Shimizu, N; Shimizu, S; Sogabe, T | 1 |
Brand, L; Wu, P | 1 |
Deibel, MR; Epps, DE; Guido, DM; Mathews, WR; Richard, KA; Staite, ND; Yem, AW | 1 |
Deibel, MR; Epps, DE; Fisher, JF; McGee, JE; Paslay, JW; Yem, AW | 1 |
Choma, CT; Kaplan, H | 1 |
Deyashiki, Y; Hara, A; Nakayama, T; Sawada, H; Shinoda, M; Tanabe, H | 1 |
Cui, K; Lu, AY; Ma, Q; Wang, RW; Yang, CS | 1 |
Kalcheva, HO; Maluta, SS; Shanskaya, VO; Smutny, J | 1 |
Bhattacharyya, R; Samanta, TK | 1 |
Sen, SK | 1 |
Huynh, QK | 1 |
Goldstein, S; Harp, JB; Phillips, LS | 1 |
Kal'cheva, EO; Kmet, V; Maliuta, SS | 1 |
Dulik, DM; Hayden, PJ; McCann, DJ; Stevens, JL; Ward, AJ; Yang, Y | 1 |
Cornille, F; Darlix, JL; de Billy, G; Housset, V; Prats, AC; Prats, H; Roques, B | 1 |
Del Boccio, G; Federici, G; Lo Bello, M; Pennelli, A; Petruzzelli, R; Ricci, G; Whitehead, EP | 1 |
Kirsch, JF; Planas, A | 1 |
Colman, RW; Puri, RN | 1 |
Brzovic, P; Dunn, MF; Gollnick, P; Phillips, RS; Richter, I | 1 |
Birnbaum, D; Bode, R; Schmidt, H | 1 |
Bachmann, B; Kalinowski, J; Pühler, A; Thierbach, G | 1 |
Miki, M | 1 |
Goldman, E; Jakubowski, H; Rojiani, MV | 1 |
Barden, JA; Phillips, L | 1 |
Chambers, MA; Gelboin, HV; Gerber, N; Hilliard, JB; Mays, DC; Park, SS; Wong, DD | 1 |
Bradbury, EM; Marvin, KW; Yau, P | 1 |
Corey, DR; Pei, D; Schultz, PG | 1 |
Esaki, N; Matsushima, Y; Soda, K; Sung, MH; Tanizawa, K; Wakayama, M; Yamauchi, T; Yoshimura, T | 1 |
Busiello, V; Coccia, R; Di Girolamo, M; Foppoli, C | 1 |
Bayer, EA; Safars, M; Wilchek, M | 1 |
Ebina, S; Lerner, RA; Wright, PE | 1 |
Clore, GM; Graber, P; Gronenborn, AM; MacDonald, HR; Shaw, AR; Wingfield, P | 1 |
Ahmed, SA; Kawasaki, H; Miles, EW; Morita, H; Nagata, S | 1 |
Harano, K; Harano, T; Imai, K; Tsuneshige, A | 1 |
Fay, PJ; Smudzin, TM | 1 |
Blarzino, C; Busiello, V; Cini, C; Di Girolamo, M | 1 |
Busiello, V; Cini, C; de Marco, C; di Girolamo, A; di Girolamo, M | 2 |
Chapman, D; Herzyk, E; Owen, JS | 1 |
Busiello, V; De Marco, C; Di Girolamo, A; Di Girolamo, M; Foppoli, C | 1 |
de Graaf, FK; Jacobs, AA; van Mechelen, JR | 1 |
Inano, H; Tamaoki, B | 1 |
Friedman, M; Grosjean, OK; Zahnley, JC | 1 |
Blarzino, C; De Marco, C; Di Girolamo, A; Di Girolamo, M; Foppoli, C | 1 |
Igarashi, K; Ito, K | 1 |
Amaral, L; Lee, Y; Lorian, V; Schwarz, U | 1 |
Busiello, V; Cini, C; Coccia, R; Di Girolamo, A; Di Girolamo, M; Foppoli, C | 1 |
Alvarez, E; López-Nieto, MJ; Martín, JF; Ramos, FR; Revilla, G | 1 |
Gilles, P; Keudell, KC; Robertson, NL | 1 |
Klaude, M; von der Decken, A | 1 |
Glaser, KB; Jacobs, RS | 1 |
Busiello, V; Cini, C; Di Girolamo, A; Di Girolamo, M; Foppoli, C | 1 |
Barden, JA; dos Remedios, CG; Miki, M | 1 |
Deutzmann, R; Glanville, RW; Hofmann, H; Kühn, K; Qian, RA; Siebold, B | 1 |
Gershoni, JM; Mosckovitz, R | 1 |
Berden, JA; Hartog, AF; Persson, B; Rydström, J | 1 |
Inano, H | 1 |
Busiello, V; Cini, C; Coccia, R; Di Girolamo, A; Di Girolamo, M | 2 |
Auchus, RJ; Bork, V; Covey, DF; Schaefer, J | 1 |
Dobryszycki, P; Kochman, M | 1 |
Blarzino, C; Busiello, V; Coccia, R; Di Girolamo, A; Di Girolamo, M | 1 |
Bhatnagar, D; Puri, RN; Roskoski, R | 1 |
dos Remedios, CG; Miki, M | 1 |
Busiello, V; Cini, C; Di Girolamo, A; Di Girolamo, M | 1 |
Katayama, I; Nishioka, K | 1 |
Hosokawa, Y; Niizeki, S; Sato, I; Tojo, H; Yamaguchi, K | 1 |
Finot, PA; Hurrell, RF; Nielsen, HK | 1 |
Blarzino, C; Coccia, R; Di Girolamo, A; Di Girolamo, M; Foppoli, C | 1 |
Leluk, J; Pham, TC; Polanowski, A; Wilusz, T | 1 |
Karlsson, JO; Sjöstrand, J | 1 |
Fleet, GW; Knowles, JR; Porter, RR | 1 |
Müller-Eberhard, HJ; Vallota, EH | 1 |
Everett, MM; Miller, WA | 3 |
Chung, AE; Edwards, DJ; Heinrikson, RL | 1 |
De Lorenzo, F; Givol, D | 1 |
Singer, SJ; Slobin, LI | 1 |
Marinetti, GV; Pettit, D | 1 |
Berns, DS; Habig, W; MacColl, R | 1 |
Ellis, HK; Watkins, WB | 1 |
Bolt, HM; Kappus, H | 2 |
Demain, AL | 1 |
Azumi, T | 1 |
Oe, M; Seon, BK; Titani, K; Tonomura, Y | 1 |
Braun, V; Rehn, K; Wolff, H | 1 |
Hallberg, D; Soda, M | 1 |
Garcet, S; Huyen, VN; Servin, A | 1 |
Bürgi, W; Colombo, JP; Richterich, R | 1 |
Mathew, E; Meriwether, BP; Park, JH | 1 |
Schoffa, G | 1 |
Broquist, HP; Hogg, RW | 1 |
Hirsh, DI; Lipmann, F | 1 |
Darnall, DW; Garbett, K; Klotz, IM | 1 |
D'Alessio, G; Josse, J | 1 |
Calabrese, L; Rotilio, G | 1 |
Karadźić, V; Micić, D; Rakić, L | 1 |
Lemke, PA; Nash, CH | 1 |
Ward, S | 1 |
Coudert, M; Vandecasteele, JP | 1 |
Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
Degani, Y; Nyc, JF; Smith, EL; Veronese, FM | 1 |
Miyajima, R; Otsuka, S; Shiio, I | 1 |
Read, CP; Southworth, GC | 1 |
de Bruin, SH; Janssen, LH; van Os, GA; Willekens, FL | 1 |
Hochberg, AA; Zevin-Sonkin, D | 1 |
Elmore, DT; Roberts, DV | 1 |
Attardi, G; Costantino, P | 1 |
Hirshfield, IN; Zamecnik, PC | 1 |
Hirshfield, IN; Tomford, JW; Zamecnik, PC | 1 |
Kotyk, A; Ríhová, L | 1 |
Biserte, G; Dautrevaux, M; Han, K | 1 |
Horecker, BL; Lai, CY | 1 |
Lemieux, G | 1 |
Lichtenstein, N; Lustig, N; Spiegelstein-Klarfeld, H | 1 |
Banks, TE; Shafer, JA | 2 |
Host, WR; Rush, BF; Serlin, O | 1 |
Deutsch, HF; Lin, KT | 2 |
Hoff, JE; Jones, CM; Rodis, P; Sosa, MP | 1 |
Bradbury, JH; Ley, KF | 1 |
Deetjen, P; Silbernagl, S | 1 |
Meigel, W; Müller, PK; Pontz, B | 1 |
Van Campen, D | 1 |
Greth, WE; Segal, S; Thier, SO | 1 |
Fasold, H; Meyer, C; Steinkopff, G | 1 |
Good, RA; Jose, DG | 1 |
Morino, Y; Okamoto, M | 1 |
Chirgadze, YN; Shestopalov, BV; Venyaminov, SY | 1 |
Meloche, HP | 1 |
Philip, G; Soman, G | 1 |
Adler, AJ; Fasman, GD; Greenfield, NJ | 1 |
Kirschenbaum, DM | 1 |
Read, CP; Ruff, MD | 1 |
Ax, HA; Berger, J; Janecek, J; Kellett, M; Pruess, DL; Scannell, JP; Stempel, A; Williams, TH | 1 |
Soda, K; Tanaka, H | 1 |
Lazdunski, M; Schweitz, H; Vincent, JP | 1 |
Blethen, SL; Boeker, EA; Snell, EE | 1 |
Chow, RB; Kassel, B | 1 |
Horecker, BL; Morse, DE | 1 |
Scriver, CR | 1 |
Singer, SJ | 1 |
Butler, JA; Johns, EW; Phillips, DM | 1 |
Rudert, H | 1 |
Kishida, Y; Sakakibara, S | 1 |
Schechter, I | 1 |
Staehelin, M; Wehrli, W | 1 |
Beaudet, A; Caskey, CT; Nirenberg, M | 1 |
DeLange, RJ; Smith, EL | 1 |
Nurmikko, V; Pyykkö, K | 1 |
Hardman, DF; Hardman, JK | 1 |
Kotyk, A; Ponec, M; Ríhová, L | 1 |
Ilahi, M; Kelemen, MV; Rose, AH | 1 |
Yotis, WW | 1 |
Prescott, JM; Wagner, FW | 1 |
Glenner, GG; Hopsu, VK; Mäkinen, KK | 1 |
Pierpoint, WS | 1 |
Mirsky, R | 1 |
Jarvis, B | 1 |
Morgan, J | 1 |
Farr, J; Jarvis, B | 1 |
Appella, E; Hannon, JE; Inman, JK | 1 |
Lazdunski, M; Vincent, JP | 1 |
Marzluff, WF; McCarty, KS | 1 |
Jacobsen, C | 1 |
Ciegler, A; Leistner, L; Mintzlaff, HJ; Weisleder, D | 1 |
Diopoh, J; Olomucki, M | 1 |
Brew, K | 1 |
Ruckhäberle, KE; Viehweg, B; Wolff, C | 3 |
Maclean, CW | 1 |
Mäkinen, KK; Mäkinen, PL | 1 |
Charpentier, C; Lemonnier, A; Levillain, P; Moatti, N | 1 |
Hornig, D; Weber, F; Wiss, O | 1 |
Haniu, M; Massey, V; Matsueda, G; Mayhew, S; Tanaka, M; Yasunobu, KT | 1 |
Anthony, C; Drabble, WT; Robinson, JH | 1 |
Markelova, SI; Zharikova, GG | 3 |
Kassab, R; Pradel, LA; Roustan, C; Van Thoai, N | 1 |
Furka, A | 1 |
Chen, R; Doolittle, RF; Lau, F | 1 |
Churchich, JE; Wampler, J | 1 |
Kabat, EA | 1 |
Gibbons, RJ; Loesche, WJ | 1 |
Guest, JR; Yanofsky, C | 1 |
Fedorchenko, EIa; Gulyi, MF; Orlov, LP; Petrun', LM; Pisarevich, EV | 1 |
Bender, E; Rahn, I; Schwabe, K; Widmaier, R | 1 |
Cooper, IA; Firkin, BG | 1 |
Bolinder, AE | 1 |
Barker, HA; Chirpich, TP; Costilow, RN; Zappia, V | 1 |
Barker, HA; Zappia, V | 1 |
Neuhoff, V; Weise, M | 1 |
Melcher, G | 1 |
Copeland, W; Kelly, S; Leikhim, E | 1 |
Baranova, IP; Egorov, NS | 1 |
Hampton, JR | 1 |
Chalkley, R; Oliver, D; Panyim, S; Spiker, S | 1 |
Crawhall, JC; Davis, MG | 1 |
Berry, K; Diamond, S; Hansen, S; Mok, C; Perry, TL | 1 |
Chirgadze, YN; Lobachev, VM; Venyaminov, SY | 1 |
Ellfolk, N | 1 |
Konovalova, ZB | 1 |
Ansorge, S; Bohley, P | 1 |
Ashmarin, IP; Diurnbaum, VI; Sadikova, NV; Stapanova, IS | 1 |
Demeyer, DI; Henderickx, HK | 1 |
Bachmayer, H; Mayhew, S; Peel, JL; Yasunobu, KT | 1 |
Daniel, JC; Olson, JD | 1 |
Carpenter, FH; Wang, SS | 1 |
Graves, DJ; Philip, G | 1 |
Manahan, J; Mandl, I | 1 |
Steenbergen, ST; Weinberg, ED | 1 |
Fasman, GD; Potter, J; Stevens, L; Timasheff, SN; Townend, R | 1 |
Schneider, G | 1 |
Belcher, RV; Lockwood, WH; Rimington, C | 1 |
Pogosova, AV; Rapoport, EA | 1 |
Jansen, EF; Olson, AC | 1 |
Antonioli, JA; Christensen, HN | 1 |
Fondy, TP; Ross, CR; Sollohub, SJ | 1 |
Soda, K; Tanaka, H; Yamamoto, T | 1 |
Iakobson, LM; Konnikova, AS; Korotkina, RN; Zak, AF | 1 |
Beyer, H; Schenk, U | 1 |
Connell, GE; Szewczuk, A | 1 |
Agnello, CF; Mathew, E; Park, JH | 2 |
Hall, A; Newberne, PM; Wogan, GN | 1 |
McClare, CW; Richards, EG; Snow, DL | 1 |
Hope, DB; Horncastle, KC | 1 |
Blair, A; Schwartzman, L; Segal, S | 2 |
Crawhall, JC; Segal, S | 1 |
Munier, RL; Sarrazin, G | 1 |
Stadler, DR | 1 |
Ebata, M; Otsuka, H; Takahashi, Y | 1 |
Elinov, NP; Kashkin, AP | 1 |
Crawhall, JC; Rosenberg, LE; Segal, S | 1 |
Harper, E; Scharrer, B; Seifter, S | 1 |
Lal, DN; Srivastava, AS | 1 |
Murer, H | 1 |
Dalton, B; Ogburn, CA; Paucker, M; Rusckowski, M | 1 |
Chaudhuri, A; Mishra, AK; Nanda, G | 1 |
Sutoh, K | 1 |
Deschamps, A; Noel, C; Plichon, B | 1 |
Hitchcock, MJ; Hodgson, B; Linforth, JL | 1 |
Bazaes, S; Beytía, E; Eyzaguirre, J; Gómez, I; Jabalquinto, AM; Solís de Ovando, F | 1 |
Busiello, V; Cini, C; De Marco, C; Di Girolamo, M | 1 |
Aharonowitz, Y; Mendelovitz, S | 1 |
Wu, CH; Wu, GY | 1 |
Korn, ED; Lal, AA; Vandekerckhove, J | 1 |
Busiello, V; Cini, C; Coccia, R; Di Girolamo, M | 1 |
Busiello, V; Cinia, C; Coccia, R; de Marco, C; Di Girolamo, M | 1 |
Berio, A | 2 |
Blarzino, C; Busiello, V; Cini, C; De Marco, C; Di Girolamo, M | 1 |
Burtnick, LD; Isaac, CD | 1 |
Schafer, JA; Watkins, ML | 1 |
Elzinga, M; Phelan, JJ | 1 |
Ikemoto, N | 1 |
Maas, WK; Popkin, PS | 1 |
Baker, DH; Finley, JW; Robbins, KR | 1 |
Fujioka, M; Hase, T; Ogawa, H | 1 |
el-Hawary, MF; el-Shawarby, N; el-Shobaki, FA; Sakr, R | 1 |
Corcoran, DH; Ferguson, EW; Fretto, LJ; McKee, PA | 1 |
Engel, PC; Gould, KG | 1 |
Friedman, M; Gumbmann, MR | 1 |
Bloxham, DP; Ericsson, LH; Kumar, S; Neurath, H; Parmelee, DC; Titani, K; Wade, RD; Walsh, KA | 1 |
Holz, F | 1 |
Bhattacharjee, JK; Zwolshen, JH | 1 |
Gracy, RW; Lu, HS | 1 |
Kilberg, MS | 1 |
Halban, PA | 1 |
Buckley, JT; Hardie, KR; Parker, MW; van der Goot, FG | 1 |
Cerione, RA; Erickson, JW; Mittal, R | 1 |
Gloss, LM; Kirsch, JF | 3 |
Barry, PH; Cunningham, AM; French, PW; Pierce, KD; Rajendra, S; Schofield, PR; Vandenberg, RJ | 1 |
Bird, M; Britten, C; Hood, C | 1 |
Michelangeli, F | 1 |
Bradford, GD; Gous, RM; Martin, PA | 1 |
Huang, DY; Ichikawa, Y | 1 |
Denny, BJ; Lambert, PA; Poyner, DR | 1 |
Offer, G; Sessions, R | 1 |
Feix, JB; Hogg, N; Kalyanaraman, B; Mchaourab, HS; Singh, RJ | 1 |
Altenbach, C; Ding, LL; Farahbakhsh, ZT; Horwitz, J; Huang, QL; Hubbell, WL; Steinhoff, HJ | 1 |
Battistoni, A; Board, PG; Federici, G; Lo Bello, M; Mazzetti, AP; Muramatsu, M; Ricci, G | 1 |
Armstrong, VW; Brunner, C; Ernst, A; Helmhold, M; Müller, HJ; Pethö-Schramm, A | 1 |
Klein, RR; Salvucci, ME | 1 |
Bustin, M; Friedman, FK; Lehn, DA; Postnikov, YV; Robinson, RC; Shiloach, J | 1 |
Cranwell, PD; Darragh, AJ; Moughan, PJ | 1 |
Adachi, Y; Kai, D; Kaya, S; Nakamura, Y; Taniguchi, K | 1 |
Coleman, CS; Pegg, AE; Stanley, BA; Viswanath, R | 1 |
Aoyagi, S; Baker, DH | 1 |
Bazaes, S; Cardemil, E; Goldie, H; Jabalquinto, AM; Silva, R | 1 |
Esaki, N; Kagamiyama, H; Kim, DW; Kuramitsu, S; Matsushima, Y; Soda, K; Yoshimura, T | 1 |
Esaki, N; Kim, DW; Satoh, E; Soda, K; Yoshimura, T | 1 |
Hu, WS; Malmberg, LH; Sherman, DH | 1 |
Kim, IY; Stadtman, TC; Veres, Z | 1 |
Katiyar, SS; Mukunda, K; Sheikh, S | 1 |
Curran, T; Forrest, D; Ng, L | 1 |
Mims, MP; Morrisett, JD; Sparrow, JT; Sturgis, CB | 1 |
Le Blois, H; Roy, P | 1 |
Dunten, RL; Kaback, HR; Sahin-Tóth, M | 1 |
Iio, T; Miki, M | 1 |
Kahana, C; Tobias, KE | 1 |
Ash, DE; Werneburg, BG | 1 |
Frankard, V; Ghislain, M; Jacobs, M | 1 |
Cho, SW; Choi, SY; Hong, JW; Lee, SJ | 1 |
Grabarek, Z; Mabuchi, Y; Tan, RY | 1 |
Benditt, M; Christner, P; Jimenez, SA; Yankowski, RL | 1 |
Katiyar, S; Pandey, A; Sheikh, S | 1 |
Hult, T; Lindberg, U; Strzelecka-Golaszewska, H; Wozniak, A | 1 |
East, JM; Khan, YM; Lee, AG; Wictome, M | 1 |
dos Remedios, CG; Hambly, BD; Huang, W; Kekic, M; Moens, PD | 1 |
Imai, S; Kai, M; Kanoh, H; Sakane, F; Wada, I | 1 |
Czaplinski, K; Peltz, SW; Weng, Y | 1 |
Cui, DS; Dyson, HJ; Holmgren, A; Jeng, MF; Kuprin, S; Lindell, M; Slaby, I; Tennant, LL | 1 |
Peter-Katalinić, J; Rizner, TL; Strupat, K; Zakelj-Mavric, M; Zorko, M | 1 |
Andersson, C; Bergman, T; Ekström, L; Morgenstern, R; Raza, H; Weinander, R | 1 |
Honma, M; Ito, H; Kiuchi, M; Matsui, H; Murakami, T | 1 |
Cho, SW; Lee, JE | 1 |
Carne, AF; U, S | 1 |
Dahl, G; Hudder, A; Llanes, A; Luebke, A; Pfahnl, A; Werner, R; Zhou, XW | 1 |
Balser, JR; Chiamvimonvat, N; Marban, E; Pérez-García, MT; Ranjan, R; Tomaselli, GF | 1 |
Beranová, S; Giorgianni, F; Viola, RE; Wesdemiotis, C | 1 |
Katiyar, SS; Pandey, A | 1 |
Calendar, R; Lanka, E; Lurz, R; Ziegelin, G | 1 |
Abe, M; Funaba, M; Iriki, T | 1 |
Bergman, AC; Bonetto, V; Jörnvall, H; Sillard, R | 2 |
Balis, C; Kyriacou, A; Typas, MA | 1 |
Sine, SM | 1 |
Douglas, MW; Johnson, ML; Parsons, CM | 1 |
Rao, M; Rawat, U | 1 |
Nishino, T | 1 |
Laage, R; Langosch, D | 1 |
Dougherty, DA; Gallivan, JP; Lester, HA | 1 |
Benítez, T; Gasent-Ramírez, JM | 1 |
Marrone, L; Viswanatha, T | 1 |
Franklin, E; Mantle, TJ; Walsh, SB | 1 |
Foster, DC; Linde, V; Nielsen, LS; Petersen, LC | 1 |
Chagas, EP; Santoro, LG | 1 |
Komath, SS; Nadimpalli, SK; Swamy, MJ | 1 |
Dupont, DR; Hsi, KL; O'Neill, SA; Yuan, PM | 1 |
Chen, JG; Liu-Chen, S; Rudnick, G | 1 |
McKay, DB; Wilbanks, SM | 1 |
Hild, G; Lakos, Z; Nyitrai, M; Somogyi, B | 1 |
Cole, JA; Eaves, DJ; Griffiths, I; Grove, J; James, P; Poole, RK; Staudenmann, W; White, SA | 1 |
de Jersey, J; Emmerson, BT; Gee, CL; Keough, DT | 1 |
Kotovych, G; McClung, RE; Nakashima, TT | 1 |
Gabriel, D; Heidecker, M; Marriott, G; Ottl, J | 1 |
Bashford, D; Dillet, V; Dyson, HJ | 1 |
Clonis, YD; Kotsira, VP | 1 |
Homma, K; Maruta, S; Ohki, T | 1 |
Auzou, G; Lupo, B; Mesnier, D | 1 |
Aschbaher, M; Clifford, T; Cox, S; Gangal, M; Garrod, SM; Johnson, DA; Lew, J; Taylor, SS | 1 |
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38 review(s) available for lysine and cysteine
Article | Year |
---|---|
Amino acid requirements.
Topics: Amino Acids, Essential; Animals; Body Weight; Cysteine; Diet; Dietary Proteins; Lysine; Methionine; Nutritional Requirements; Species Specificity; Swine; Threonine | 1976 |
Biochemistry of penicillin and cephalosporin fermentations.
Topics: Acremonium; Adipates; Carbon Radioisotopes; Cephalosporins; Culture Media; Cysteine; Fermentation; Fungi; Isomerism; Lactams; Lysine; Methionine; Mutation; Penicillin G; Penicillins; Penicillium; Penicillium chrysogenum; Streptomyces; Sulfur Radioisotopes; Valine | 1974 |
[Chemical modifications of proteins: application to the study of their covalent structure (continuation and end)].
Topics: Aspartic Acid; Carbon Isotopes; Cysteine; Cystine; Electrophoresis, Paper; Lysine; Methionine; Methods; Peptides; Protein Conformation; Protein Hydrolysates; Proteins; Serine | 1972 |
Aldolase: a model for enzyme structure-function relationships.
Topics: Age Factors; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Crystallization; Cyanogen Bromide; Cysteine; Fructose-Bisphosphate Aldolase; Histidine; Isoenzymes; Lysine; Macromolecular Substances; Models, Chemical; Muscles; Plants; Rabbits; Saccharomyces cerevisiae; Schiff Bases; Species Specificity; Structure-Activity Relationship; Tyrosine | 1972 |
The mechanism of action of aldolases.
Topics: Amino Acid Sequence; Animals; Bacteria; Binding Sites; Biological Evolution; Carbohydrate Metabolism, Inborn Errors; Cattle; Chelating Agents; Chemistry, Organic; Cysteine; Fructose; Fructose-Bisphosphate Aldolase; Genetics; Histidine; Liver; Lysine; Metals; Models, Chemical; Molecular Weight; Muscles; Organ Specificity; Organic Chemistry Phenomena; Phosphates; Rabbits; Rats; Saccharomyces; Tyrosine | 1968 |
Use of human genetic variation to study membrane transport of amino acids in kidney.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Child; Cysteine; Genetics, Medical; Heterozygote; Homozygote; Humans; Kidney; Lysine; Male; Mutation; Proline; Renal Tubular Transport, Inborn Errors | 1969 |
Covalent labeling of active sites.
Topics: Amino Acid Sequence; Amino Acids; Antibodies; Binding Sites; Carbon Isotopes; Chymotrypsin; Cysteine; Haptens; Histidine; Isoflurophate; Lysine; Models, Chemical; Phosphoglucomutase; Proteins; Trypsin; Tryptophan; Tyrosine | 1967 |
Recent investigations on histones and their functions.
Topics: Amino Acids; Animals; Arginine; Cattle; Cysteine; DNA; Electrophoresis, Disc; Gels; Histones; Lysine; Methods; Nucleoproteins; Peptide Hydrolases; Peptides; Plants; Rats; RNA; Serine; Thymus Gland; Trypsin | 1968 |
[Synthesis of peptides by solid phase method. 1].
Topics: Arginine; Asparagine; Cysteine; Esters; Glutamine; Histidine; Lysine; Methionine; Methods; Peptides; Polystyrenes; Serine; Threonine | 1971 |
Histones: structure and function.
Topics: Acetates; Acylation; Amino Acid Sequence; Animals; Arginine; Cattle; Chemical Phenomena; Chemistry; Chromatin; Cysteine; Cystine; DNA; Female; Histidine; Histones; Lysine; Male; Methylation; Molecular Weight; Oxidation-Reduction; Phosphoproteins; Phosphoric Acids; Protein Binding; Protein Conformation; RNA; Serine; Thymus Gland | 1971 |
Renal transport of amino acids: membrane mechanisms.
Topics: Amino Acids; Animals; Cell Membrane Permeability; Cysteine; Cystine; gamma-Glutamyltransferase; Kidney; Kidney Concentrating Ability; Kidney Tubules, Proximal; Lysine; Microvilli; Rats | 1982 |
Structure and function of the calcium pump protein of sarcoplasmic reticulum.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cysteine; Histidine; Humans; Lysine; Magnesium; Protein Conformation; Sarcoplasmic Reticulum | 1982 |
Amino acid transport in isolated rat hepatocytes.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Catecholamines; Cell Membrane; Cells, Cultured; Cysteine; Glucagon; Glucocorticoids; Glutamine; Glycine; Histidine; In Vitro Techniques; Insulin; Kinetics; Liver; Lysine; Rats | 1982 |
Transgene-mediated modifications to animal biochemistry.
Topics: Animals; Cysteine; Gene Transfer Techniques; Glyoxylates; Lysine; Threonine; Transgenes | 2000 |
Nano-tailoring; stitching alterations on viral coats.
Topics: Biocompatible Materials; Capsid Proteins; Cysteine; Lysine; Nanotechnology; Tyrosine; Viruses | 2004 |
Peptidomics, current status.
Topics: Arginine; Chromatography, Affinity; Combinatorial Chemistry Techniques; Cysteine; Histidine; Humans; Lysine; Methionine; Peptides; Phosphotyrosine; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2005 |
Improving the levels of essential amino acids and sulfur metabolites in plants.
Topics: Amino Acids, Essential; Cysteine; Lysine; Methionine; Plants; Protein Engineering; Sulfur | 2005 |
Yeast as a biosensor for antioxidants: simple growth tests employing a Saccharomyces cerevisiae mutant defective in superoxide dismutase.
Topics: Acetylcysteine; Air; Antioxidants; Atmosphere; Biosensing Techniques; Cysteine; Lysine; Methionine; Mutation; Saccharomyces cerevisiae; Superoxide Dismutase | 2005 |
Protein stains for proteomic applications: which, when, why?
Topics: Colorimetry; Cysteine; Electrophoresis, Gel, Two-Dimensional; Fluorescent Dyes; Glycoproteins; Hydrogen-Ion Concentration; Image Processing, Computer-Assisted; Lysine; Proteins; Proteomics; Rosaniline Dyes; Sensitivity and Specificity; Silver Nitrate; Spectrophotometry | 2006 |
Genetically engineered Tobacco mosaic virus as nanoparticle vaccines.
Topics: Antigens, Viral; Cysteine; Genetic Engineering; Green Fluorescent Proteins; Immunity, Cellular; Lysine; Nanoparticles; Tobacco Mosaic Virus; Vaccines | 2008 |
Difference gel electrophoresis based on lys/cys tagging.
Topics: Animals; Cysteine; Electrophoresis, Gel, Two-Dimensional; Fluorescent Dyes; Humans; Image Processing, Computer-Assisted; Lysine; Proteins | 2008 |
Protein lysine acylation and cysteine succination by intermediates of energy metabolism.
Topics: Acylation; Animals; Cysteine; Energy Metabolism; Humans; Lysine; Protein Processing, Post-Translational; Proteins | 2012 |
Current ADC Linker Chemistry.
Topics: Antibodies, Monoclonal; Cysteine; Immunoconjugates; Lysine; Pharmaceutical Preparations; Protein Engineering | 2015 |
Exploring the glycan interaction in vivo: Future prospects of neo-glycoproteins for diagnostics.
Topics: Amination; Animals; Carbohydrate Sequence; Cysteine; Glycoconjugates; Glycoproteins; Glycosylation; Injections, Intravenous; Lysine; Mice; Monosaccharides; Oligosaccharides; Optical Imaging; Oxidation-Reduction; Positron Emission Tomography Computed Tomography; Single Photon Emission Computed Tomography Computed Tomography | 2016 |
Signaling by 4-hydroxy-2-nonenal: Exposure protocols, target selectivity and degradation.
Topics: Aldehydes; Animals; Autophagy; Cysteine; Histidine; Humans; Lipid Peroxidation; Lysine; Lysosomes; Oxidative Stress; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Signal Transduction | 2017 |
Clinical Experience with
Topics: Antigens, Surface; Cysteine; Drug Evaluation, Preclinical; Fluorine Radioisotopes; Glutamate Carboxypeptidase II; Glutarates; Humans; Lysine; Male; Organophosphonates; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Urea | 2017 |
Features and regulation of non-enzymatic post-translational modifications.
Topics: Animals; Cysteine; Humans; Lysine; Mice; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Proteins; Proteomics; Signal Transduction | 2018 |
Reactive Chemical Probes: Beyond the Kinase Cysteinome.
Topics: Cysteine; Humans; Lysine; Mass Spectrometry; Molecular Conformation; Protein Kinase Inhibitors; Protein Kinases; Proteomics | 2018 |
The Causes and Consequences of Nonenzymatic Protein Acylation.
Topics: Acyl Coenzyme A; Acylation; Animals; Cysteine; Humans; Lysine; Protein Processing, Post-Translational; Proteins | 2018 |
Modifications of recombinant monoclonal antibodies in vivo.
Topics: Animals; Antibodies, Monoclonal; Asparagine; Cysteine; Disulfides; Glutamine; Glycosylation; Humans; Lysine; Pharmaceutical Preparations; Protein Processing, Post-Translational; Recombinant Proteins; Succinimides; Time Factors | 2019 |
A Genetically Encoded, Phage-Displayed Cyclic-Peptide Library.
Topics: Cyclization; Cysteine; Genetic Code; Humans; Ligands; Lysine; Peptide Library; Peptides, Cyclic | 2019 |
[Development and Application of Catalytic Tyrosine Chemical Modification].
Topics: Catalysis; Cysteine; Electron Transport; Electrons; Hemin; Luminol; Lysine; Oxidation-Reduction; Peroxidase; Proteins; Ruthenium; Tyrosine | 2019 |
Tyrosine Conjugation Methods for Protein Labelling.
Topics: Cysteine; Immunoconjugates; Lysine; Proteins; Staining and Labeling; Tyrosine | 2020 |
Site-selective lysine conjugation methods and applications towards antibody-drug conjugates.
Topics: Binding Sites, Antibody; Cysteine; Humans; Hydrophobic and Hydrophilic Interactions; Immunoconjugates; Lysine; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Engineering; Protein Processing, Post-Translational; Structure-Activity Relationship | 2021 |
Positive Regulation of the Antiviral Activity of Interferon-Induced Transmembrane Protein 3 by S-Palmitoylation.
Topics: Animals; Antiviral Agents; Cysteine; Interferons; Lipoylation; Lysine; RNA-Binding Proteins | 2022 |
Chemical Conjugation to Less Targeted Proteinogenic Amino Acids.
Topics: Amines; Amino Acids; Cysteine; Lysine; Proteins; Tyrosine | 2022 |
The expanding impact of methylglyoxal on behavior-related disorders.
Topics: Arginine; Cysteine; Dopamine; Glycation End Products, Advanced; Humans; Lysine; Magnesium Oxide; Mental Disorders; Nucleotides; Pain; Pyruvaldehyde | 2023 |
[Advances in applications of activity-based chemical probes in the characterization of amino acid reactivities].
Topics: Amino Acids; Cysteine; Humans; Lysine; Proteome; Proteomics | 2023 |
1 trial(s) available for lysine and cysteine
Article | Year |
---|---|
Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma.
Topics: Acetates; Administration, Inhalation; Adult; Aspirin; Asthma; Confidence Intervals; Cross-Over Studies; Cyclopropanes; Cysteine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Leukotrienes; Lysine; Male; Middle Aged; Nasal Provocation Tests; Peak Expiratory Flow Rate; Quinolines; Reference Values; Reproducibility of Results; Spirometry; Sulfides | 2004 |
855 other study(ies) available for lysine and cysteine
Article | Year |
---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation.
Topics: beta-Alanine; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Magnetic Resonance Spectroscopy; Peptides; Pyruvaldehyde | 2009 |
Affinity labeling of a previously undetected essential lysyl residue in class I fructose bisphosphate aldolase.
Topics: Affinity Labels; Amino Acids; Animals; Binding Sites; Cysteine; Dihydroxyacetone Phosphate; Ethanolamines; Fructose-Bisphosphate Aldolase; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Muscles; Organophosphorus Compounds; Protein Binding; Rabbits | 1976 |
Chemotaxis toward amino acids by Bdellovibrio bacteriovorus.
Topics: Amino Acids; Asparagine; Bdellovibrio; Chemotaxis; Cysteine; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Lysine; Temperature; Threonine | 1977 |
Lysinoalanine formation in protein food ingredients.
Topics: Alanine; Chemical Phenomena; Chemistry; Cysteine; Dietary Proteins; Disulfides; Food Handling; Hydrogen-Ion Concentration; Kinetics; Lysine | 1977 |
Specific hydrolysis by trypsin at alkaline pH.
Topics: Amino Acid Sequence; Arginine; Cysteine; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Methods; Substrate Specificity; Trypsin | 1977 |
Uptake and metabolism of alpha-aminoadipic acid by Penicillium chrysogenum Wis 54-1255.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Carbon Dioxide; Cysteine; Hydrogen-Ion Concentration; Lysine; Penicillin G; Penicillium; Penicillium chrysogenum; Valine | 1978 |
Recombinant human Lys-plasmin and the Lys-plasmin . streptokinase complex.
Topics: Binding Sites; Cysteine; Enzyme Activation; Fibrinolysin; Humans; Kinetics; Lysine; Macromolecular Substances; Protein Binding; Streptokinase | 1979 |
Structural proteins of simian virus 40. I. Histone characteristics of low-molecular-weight polypeptides.
Topics: Amino Acids; Animals; Arginine; Carbon Radioisotopes; Cell Line; Cysteine; Electrophoresis, Polyacrylamide Gel; Haplorhini; Histones; Kidney; Lysine; Molecular Weight; Peptides; Simian virus 40; Sulfur Radioisotopes; Tritium; Tryptophan; Viral Proteins | 1975 |
Participation of lysine-sensitive aspartokinase in threonine production by S-2-aminoethyl cysteine-resistant mutants of Serratia marcescens.
Topics: Aspartate Kinase; Cysteine; Drug Resistance, Microbial; Enzyme Repression; Lysine; Mutation; Phosphotransferases; Serratia marcescens; Threonine | 1979 |
Interaction of amino acids with silver(I) ions.
Topics: Amino Acids; Arginine; Binding Sites; Cysteine; Cystine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methionine; Potentiometry; Proteins; Silver | 1975 |
Genetic control of lysine permeases in Saccharomycopsis lipolytica.
Topics: Ascomycota; Canavanine; Cysteine; Drug Resistance, Microbial; Lysine; Membrane Transport Modulators; Membrane Transport Proteins; Mutation; Recombination, Genetic; Saccharomycopsis | 1979 |
Step-wise cross-linking of pig heart lactate dehydrogenase by a heterobifunctional reagent.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Indicators and Reagents; L-Lactate Dehydrogenase; Lysine; Maleimides; Myocardium; Peptide Fragments; Swine | 1978 |
Gas-liquid chromatography and mass spectrometry of lanthionine, lysinoalanine, and S-carboxyethylcysteine.
Topics: Alanine; Animals; Chromatography, Gas; Cysteine; Keratins; Lysine; Mass Spectrometry; Wool | 1977 |
Identification of essential lysyl and cysteinyl residues in spinach ribulosebisphosphate carboxylase/oxygenase modified by the affinity label N-bromoacetylethanolamine phosphate.
Topics: Affinity Labels; Amino Acids; Binding Sites; Carboxy-Lyases; Cysteine; Ethanolamines; Kinetics; Lysine; Organophosphorus Compounds; Oxygenases; Plants; Ribulose-Bisphosphate Carboxylase | 1978 |
Experimental cystinuria: the cycloleucine model. II. Amino acid efflux from intestinal and renal tissues.
Topics: Amino Acids; Animals; Biological Transport; Cycloleucine; Cysteine; Cystine; Cystinuria; Female; In Vitro Techniques; Intestinal Mucosa; Lysine; Microvilli; Models, Biological; Rats; Valine | 1978 |
Purification and properties of porcine platelet aggregating factor.
Topics: Amino Acids; Animals; Blood Coagulation Factors; Carbohydrates; Cysteine; Dithiothreitol; Factor VIII; Guanidines; Lysine; Platelet Aggregation; Swine; Urea | 1978 |
The effect of age on amino acid composition of human skin collagen.
Topics: Adult; Age Factors; Aged; Aging; Aldehydes; Amino Acids; Child; Collagen; Cysteine; Female; Humans; Hydroxylysine; Hydroxyproline; Infant, Newborn; Lysine; Middle Aged; Proline; Skin | 1978 |
A pyridoxamine phosphate derivative.
Topics: Affinity Labels; Apoenzymes; Cysteine; Lysine; Methods; Organophosphorus Compounds; Protein Binding; Pyridoxamine; Spectrophotometry, Ultraviolet; Tyrosine | 1977 |
Synthesis and application of new bifunctional reagents.
Topics: Azides; Chemical Phenomena; Chemistry; Cysteine; Indicators and Reagents; Lysine; Macromolecular Substances; Maleimides; Methods; Proteins | 1977 |
Specificity of ethacrynic acid as a sulfhydryl reagent.
Topics: Cysteine; Ethacrynic Acid; Histidine; Imidazoles; L-Lactate Dehydrogenase; Lysine; Serine; Sulfhydryl Reagents | 1976 |
Overproduction of lysine by mutant strains of Escherichia coli with defective lysine transport systems.
Topics: Arginine; Aspartate Kinase; Biological Transport, Active; Carbon Radioisotopes; Culture Media; Cysteine; Escherichia coli; Genes, Regulator; Homoserine Dehydrogenase; Hydro-Lyases; Lysine; Mutation; Ornithine; Picolinic Acids | 1975 |
Amino acid transport defect in glutathione-deficient sheep erythrocytes.
Topics: Amino Acids; Animals; Cell Membrane Permeability; Cysteine; Erythrocytes; Glutathione; Lysine; Ornithine; Sheep | 1975 |
Methionine hydroxy analog supplementation of low protein calf rations.
Topics: Alanine; Amino Acids, Essential; Animal Feed; Animals; Body Weight; Cattle; Cysteine; Dietary Proteins; Female; Lysine; Male; Methionine; Milk; Nutritional Requirements; Phenylalanine | 1975 |
Some chemical properties of carboxymethyl derivatives of amino acids.
Topics: Amino Acids; Binding Sites; Cysteine; Histidine; Iodoacetates; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Molecular Conformation; Time Factors; Tritium | 1975 |
Evaluation of protein nutrition by metabolizable protein and urea fermentation potential.
Topics: Amino Acids; Animal Feed; Animals; Arginine; Body Composition; Cattle; Cysteine; Dietary Proteins; Edible Grain; Female; Fermentation; Histidine; Lactation; Lysine; Methionine; Nutritional Requirements; Pregnancy; Rumen; Silage; Urea; Zea mays | 1975 |
Ligand-exchange chromatography of amino acids on copper-, cobalt- and zinc-chelex 100.
Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Cobalt; Copper; Cysteine; Glutamates; Histidine; Ion Exchange Resins; Ligands; Lysine; Phenylalanine; Quaternary Ammonium Compounds; Serine; Threonine; Tyrosine; Zinc | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Chemical modification as a probe of the topography and reactivity of horse-spleen apoferritin.
Topics: Amides; Anhydrides; Animals; Apoferritins; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Ethylmaleimide; Ferritins; Glycine; Guanidines; Horses; Iodoacetates; Kinetics; Lysine; Maleates; Protein Binding; Protein Conformation; Spleen | 1976 |
Studies on trypsin inhbitors. Part II. Synthesis of the protected tetrapeptide (sequence 11-14) of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Animals; Cysteine; Glycine; Lysine; Peptides; Proline; Swine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors | 1976 |
Isolation of regulatory mutants of Pseudomonas acidovorans by use of amino acid analogs.
Topics: Allosteric Regulation; Amino Acids; Aspartate Kinase; Cysteine; Homoserine Dehydrogenase; Hydro-Lyases; Lysine; Mutation; Pseudomonas; Threonine; Valine | 1976 |
Synthesis of N-chloroacetyl derivatives of amino acids and their use for the conjugation of polypeptides to thiol-carrying compounds.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Indicators and Reagents; Lysine; Peptides; Sulfhydryl Compounds | 1976 |
[Comparison of the histochemical bases of epidermis differentiation in vertebrates].
Topics: Amphibians; Animals; Arginine; Cysteine; Cystine; Histidine; Histocytochemistry; Humans; Lysine; Mammals; Proteins; Reptiles; Skin | 1976 |
Amino acid transport in normal and glutathione-deficient sheep erythrocytes.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Biological Transport; Cysteine; Erythrocytes; Glutathione; In Vitro Techniques; Kinetics; Lysine; Sheep; Sodium; Temperature; Time Factors | 1976 |
Transamination of some sulphur- or selenium-containing amino acids by bovine liver glutamine transaminase.
Topics: Amino Acids; Amino Acids, Sulfur; Animals; Cattle; Chromatography, High Pressure Liquid; Cysteine; Keto Acids; Kinetics; Liver; Lysine; Methionine; Organoselenium Compounds; Selenium; Spectrophotometry, Ultraviolet; Substrate Specificity; Transaminases | 1992 |
The lysP gene encodes the lysine-specific permease.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Base Sequence; Biological Transport, Active; Chromosome Mapping; Cloning, Molecular; Cysteine; DNA Transposable Elements; Drug Resistance, Microbial; Enzyme Induction; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Genetic Complementation Test; Lysine; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Insertional; Phylogeny; Protein Conformation; Recombinant Fusion Proteins; Sequence Homology, Nucleic Acid; Transcription, Genetic | 1992 |
Brønsted analysis of aspartate aminotransferase via exogenous catalysis of reactions of an inactive mutant.
Topics: Acetates; Amines; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Catalysis; Cysteine; Formates; Hydrolysis; Lysine; Models, Chemical; Mutation; Neurotransmitter Agents; Oxaloacetates; Protons; Recombinant Proteins; Schiff Bases; Substrate Specificity | 1992 |
Heterozygosity for apolipoprotein E-4Philadelphia(Glu13----Lys, Arg145----Cys) is associated with incomplete dominance of type III hyperlipoproteinemia.
Topics: Adolescent; Adult; Aged; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Arginine; Child; Cysteine; DNA; Electrophoresis, Polyacrylamide Gel; Female; Genes, Dominant; Glutamates; Glutamic Acid; Heterozygote; Homozygote; Humans; Hyperlipoproteinemia Type III; Lysine; Male; Middle Aged; Pedigree; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 1992 |
Thialysine-resistant mutants and uptake of lysine in Schizosaccharomyces pombe.
Topics: Arginine; Biological Transport, Active; Cysteine; Drug Resistance, Microbial; Glutamates; Glutamic Acid; Kinetics; Leucine; Lysine; Schizosaccharomyces | 1992 |
Novel version of Multiple Antigenic Peptide allowing incorporation on a cysteine functionalized lysine tree.
Topics: Amino Acid Sequence; Animals; Antibodies, Protozoan; Antigens; Antigens, Protozoan; Cysteine; Epitopes; Female; Heat-Shock Proteins; Immunization; Lysine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Peptides; Plasmodium falciparum | 1992 |
Subunits asymmetry in the ternary complex of lamb liver 6-phosphogluconate dehydrogenase detected by a NADP analogue.
Topics: Animals; Binding Sites; Cysteine; Gluconates; Liver; Lysine; NADP; Phosphogluconate Dehydrogenase; Protein Conformation; Sheep | 1992 |
Active site mapping studies of malate dehydrogenase : identification of essential amino acid residues by o-phthalaldehyde.
Topics: Cysteine; Lysine; Malate Dehydrogenase; Mitochondria, Heart; o-Phthalaldehyde; Protein Conformation | 1992 |
Compact denatured state of a staphylococcal nuclease mutant by guanidinium as determined by resonance energy transfer.
Topics: Amino Acid Sequence; Cysteine; Energy Transfer; Escherichia coli; Fluorescent Dyes; Guanidine; Guanidines; Kinetics; Lysine; Mathematics; Micrococcal Nuclease; Mutagenesis, Site-Directed; Naphthalenesulfonates; Protein Denaturation; Recombinant Proteins; Tryptophan | 1992 |
Synthesis of [2-3H-ethyl]S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine and its use in covalent-binding studies.
Topics: Animals; Cysteine; Cytosol; Deuterium; Kidney; Liver; Lysine; Magnetic Resonance Spectroscopy; Microsomes; Mitochondria; Rats; Rats, Inbred F344; Tritium | 1992 |
A unique catalytic and inhibitor-binding role for Lys93 of yeast orotidylate decarboxylase.
Topics: Animals; Base Sequence; Binding Sites; Catalysis; Cysteine; Electrophoresis, Polyacrylamide Gel; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Orotidine-5'-Phosphate Decarboxylase; Saccharomyces cerevisiae | 1992 |
Hepatocyte growth factor is linked by O-glycosylated oligosaccharide on the alpha chain.
Topics: Amino Acid Sequence; Carbohydrate Conformation; Carbohydrate Sequence; Cysteine; Glycosylation; Hepatocyte Growth Factor; Humans; Lysine; Macromolecular Substances; Molecular Sequence Data; Monosaccharides; Oligosaccharides; Peptide Fragments; Recombinant Proteins | 1992 |
Orientation factor in steady-state and time-resolved resonance energy transfer measurements.
Topics: Chemical Phenomena; Chemistry, Physical; Cysteine; Dithionitrobenzoic Acid; Energy Transfer; Fluorescence Polarization; Lysine; Mathematics; Micrococcal Nuclease; Mutation; Sulfhydryl Compounds | 1992 |
Site-specific chemical modification of interleukin-1 beta by acrylodan at cysteine 8 and lysine 103.
Topics: 2-Naphthylamine; Amino Acid Sequence; Animals; Cells, Cultured; Chromatography, Ion Exchange; Cysteine; Interleukin-1; Lymphocyte Activation; Lysine; Mice; Mice, Inbred C3H; Models, Structural; Molecular Sequence Data; Peptide Mapping; Protein Conformation; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; Spectrometry, Mass, Fast Atom Bombardment; T-Lymphocytes | 1992 |
Spectral characterization of environment-sensitive adducts of interleukin-1 beta.
Topics: 2-Naphthylamine; Amino Acid Sequence; Animals; Cysteine; Humans; Interleukin-1; Kinetics; Lysine; Mice; Protein Conformation; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; Spectrometry, Fluorescence | 1992 |
Bacillus thuringiensis crystal protein: effect of chemical modification of the cysteine and lysine residues.
Topics: Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Cysteine; Endotoxins; Hemolysin Proteins; Lysine; Pest Control, Biological; Solubility | 1992 |
Chemical modification of cysteinyl, lysyl and histidyl residues of mouse liver 17 beta-hydroxysteroid dehydrogenase.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding Sites; Coenzymes; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Ligands; Liver; Lysine; Mice; Protein Binding; Spectrum Analysis; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid | 1992 |
Site-directed mutagenesis of rat liver NAD(P)H: quinone oxidoreductase: roles of lysine 76 and cysteine 179.
Topics: Animals; Base Sequence; Cloning, Molecular; Cysteine; Cytosol; Enzyme Stability; Kinetics; Liver; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD(P)H Dehydrogenase (Quinone); Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rats; Recombinant Proteins; Restriction Mapping; Substrate Specificity | 1992 |
Effect of dimethyl sulfoxide on lysine production by a mutant of Bacillus subtilis with homoserine dehydrogenase activity.
Topics: Bacillus subtilis; Cysteine; Dimethyl Sulfoxide; Homoserine Dehydrogenase; Lysine; Mutation | 1991 |
L-lysine production by S-2-aminoethyl-L-cysteine-resistant mutants of Arthrobacter globiformis.
Topics: Arthrobacter; Biotin; Culture Media; Cysteine; Drug Resistance, Microbial; Glucose; Lysine; Methylnitronitrosoguanidine; Mutagenesis; Mutation; Nitrogen; Species Specificity | 1991 |
Isolation method for lysine-excreting mutants of Arthrobacter globiformis.
Topics: Alanine; Arthrobacter; Bacteriological Techniques; Cysteine; Drug Resistance, Microbial; Lysine; Methylnitronitrosoguanidine; Mutation | 1991 |
5-Enolpyruvylshikimate-3-phosphate synthase from Escherichia coli--the substrate analogue bromopyruvate inactivates the enzyme by modifying Cys-408 and Lys-411.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Cysteine; Enzyme Activation; Escherichia coli; Hydrolysis; Kinetics; Ligands; Lysine; Molecular Sequence Data; Pyruvates; Shikimic Acid; Substrate Specificity; Transferases; Trypsin | 1991 |
Nutrition and somatomedin. XXIII. Molecular regulation of IGF-I by amino acid availability in cultured hepatocytes.
Topics: Amino Acids; Animals; Cells, Cultured; Culture Media; Cysteine; Dexamethasone; Insulin; Insulin-Like Growth Factor I; Kinetics; Liver; Lysine; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Serum Albumin; Transferrin; Tryptophan | 1991 |
[Isolation and analysis of strains of Streptococcus faecium and Streptococcus bovis resistant to S-(2-aminoethyl)-L-cysteine].
Topics: Bacterial Proteins; Carboxy-Lyases; Cysteine; Drug Resistance, Microbial; Genes, Bacterial; Lysine; Mutation; Streptococcus | 1991 |
Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine.
Topics: Amines; Amino Acids; Animals; Carbon Isotopes; Carbon-Sulfur Lyases; Cysteine; Cytosol; Fluorine; Histidine; Hydrocarbons, Fluorinated; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Lyases; Lysine; Magnetic Resonance Spectroscopy; Male; Phenols; Protein Binding; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Spectrometry, Mass, Fast Atom Bombardment; Tyrosine | 1991 |
Viral RNA annealing activities of the nucleocapsid protein of Moloney murine leukemia virus are zinc independent.
Topics: Alkylation; Amino Acid Sequence; Base Sequence; Capsid; Cloning, Molecular; Cysteine; Escherichia coli; Kinetics; Lysine; Molecular Sequence Data; Moloney murine leukemia virus; Mutation; Plasmids; RNA, Transfer, Pro; RNA, Viral; Viral Core Proteins; Zinc; Zinc Fingers | 1991 |
Interaction of glutathione transferase from horse erythrocytes with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cysteine; Dithiothreitol; Erythrocytes; Glutathione; Glutathione Transferase; Horses; Hydrogen-Ion Concentration; Lysine; Oxidation-Reduction; Spectrometry, Fluorescence; Spectrum Analysis; Sulfhydryl Reagents; Tetranitromethane; Tyrosine | 1991 |
Reengineering the catalytic lysine of aspartate aminotransferase by chemical elaboration of a genetically introduced cysteine.
Topics: Alkylation; Aspartate Aminotransferases; Binding Sites; Catalysis; Cysteine; Escherichia coli; Genetic Engineering; Kinetics; Lysine; Mutagenesis, Site-Directed | 1991 |
Inhibition of ADP-induced platelet shape change and aggregation by o-phthalaldehyde: evidence for covalent modification of cysteine and lysine residues.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Cysteine; Ethylmaleimide; Humans; Kinetics; Lysine; o-Phthalaldehyde; Platelet Aggregation; Platelet Aggregation Inhibitors; Spectrometry, Fluorescence | 1991 |
Replacement of lysine 269 by arginine in Escherichia coli tryptophan indole-lyase affects the formation and breakdown of quinonoid complexes.
Topics: Arginine; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Quinones; Tryptophanase | 1991 |
Inhibition of alpha-aminoadipate-semialdehyde dehydrogenase from Trichosporon adeninovorans by lysine and lysine analogues.
Topics: Aldehyde Oxidoreductases; Binding, Competitive; Cysteine; Glutamates; Glutamic Acid; Hydroxylysine; Kinetics; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Mitosporic Fungi; Trichosporon | 1990 |
Aspartokinase genes lysC alpha and lysC beta overlap and are adjacent to the aspartate beta-semialdehyde dehydrogenase gene asd in Corynebacterium glutamicum.
Topics: Amino Acid Sequence; Aspartate Kinase; Aspartate-Semialdehyde Dehydrogenase; Base Sequence; Cloning, Molecular; Cysteine; DNA Mutational Analysis; DNA, Bacterial; Feedback; Genes, Bacterial; Lysine; Molecular Sequence Data; Restriction Mapping | 1990 |
Resonance energy transfer between points in a reconstituted skeletal muscle thin filament. A conformational change of the thin filament in response to a change in Ca2+ concentration.
Topics: Actins; Animals; Cysteine; Energy Transfer; Fluorescent Dyes; Kinetics; Lysine; Muscles; Myosin Subfragments; Rabbits; Spectrometry, Fluorescence; Spectrophotometry; Tropomyosin; Troponin; Troponin I | 1990 |
Relationship between protein synthesis and concentrations of charged and uncharged tRNATrp in Escherichia coli.
Topics: Amino Acyl-tRNA Synthetases; Bacterial Proteins; Cysteine; Escherichia coli; Kinetics; Lysine; Mutation; Plasmids; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Trp; Tryptophan; Tryptophan-tRNA Ligase | 1990 |
19F NMR study of the myosin and tropomyosin binding sites on actin.
Topics: Actins; Animals; Cysteine; Fluorescein-5-isothiocyanate; Fluoresceins; Isothiocyanates; Lysine; Magnetic Resonance Spectroscopy; Myosins; Rabbits; Thiocyanates; Tropomyosin | 1990 |
Bioactivation of 8-methoxypsoralen and irreversible inactivation of cytochrome P-450 in mouse liver microsomes: modification by monoclonal antibodies, inhibition of drug metabolism and distribution of covalent adducts.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antibodies, Monoclonal; Benzoflavones; beta-Naphthoflavone; Binding Sites; Cells, Cultured; Cysteine; Cytochrome P-450 Enzyme System; Flavonoids; Lysine; Male; Methoxsalen; Mice; Microsomes, Liver; Phenobarbital | 1990 |
Isolation and characterization of acetylated histones H3 and H4 and their assembly into nucleosomes.
Topics: Acetylation; Binding Sites; Cell Nucleus; Chromatography, High Pressure Liquid; Cysteine; Deoxyribonuclease I; DNA; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Histones; Humans; Iodoacetamide; Lysine; Nucleosomes | 1990 |
Site-specific cleavage of duplex DNA by a semisynthetic nuclease via triple-helix formation.
Topics: Base Sequence; Cysteine; DNA; Kinetics; Lysine; Micrococcal Nuclease; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Oligonucleotide Probes; Substrate Specificity | 1990 |
Substitution of S-(beta-aminoethyl)-cysteine for active-site lysine of thermostable aspartate aminotransferase.
Topics: Amino Acids; Aspartate Aminotransferases; Aziridines; Bacillus; Binding Sites; Cysteine; Lysine; Mutagenesis, Site-Directed; Spectrophotometry | 1990 |
Aspartokinase III repression and lysine analogs utilization for protein synthesis.
Topics: Aspartate Kinase; Cysteine; Enzyme Repression; Escherichia coli; Isoenzymes; Lysine; Mutation; Organoselenium Compounds; Protein Biosynthesis; Selenium | 1990 |
Selective labeling of sulfhydryls and disulfides on blot transfers using avidin-biotin technology: studies on purified proteins and erythrocyte membranes.
Topics: Avidin; Biotin; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Humans; Lysine; Maleimides; Membrane Proteins; Mercaptoethanol; Proteins; Staining and Labeling; Sulfhydryl Compounds | 1987 |
Chemical modification of bovine pancreatic trypsin inhibitor for single site coupling of immunogenic peptides for NMR conformational analysis.
Topics: Acetylation; Aprotinin; Chemical Phenomena; Chemistry; Chymotrypsin; Cross-Linking Reagents; Cysteine; Dimyristoylphosphatidylcholine; Guanidine; Guanidines; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Methylurea Compounds; Peptides; Protein Conformation; Succinimides; Trypsin | 1989 |
Preparation, characterization and application of interleukin-1 beta mutant proteins with surface-accessible cysteine residues.
Topics: Alkylation; Amino Acids; Binding, Competitive; Cysteine; Escherichia coli; Flow Cytometry; Gene Expression Regulation; Genetic Vectors; Interleukin-1; Isoelectric Focusing; Lysine; Magnetic Resonance Spectroscopy; Mutation; Peptide Mapping; Plasmids; Protein Conformation; Recombinant Proteins; Surface Properties; Trypsin | 1989 |
The beta subunit of tryptophan synthase. Clarification of the roles of histidine 86, lysine 87, arginine 148, cysteine 170, and cysteine 230.
Topics: Arginine; Binding Sites; Cloning, Molecular; Cysteine; DNA Mutational Analysis; Histidine; Lysine; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Spectrum Analysis; Tryptophan Synthase | 1989 |
Structure-function relationships in hemoglobin Kariya, Lys-40(C5) alpha----Glu, with high oxygen affinity. Functional role of the salt bridge between Lys-40 alpha and the beta chain COOH terminus.
Topics: 2,3-Diphosphoglycerate; Cysteine; Diphosphoglyceric Acids; Disulfides; Hemoglobin A; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Macromolecular Substances; Oxygen; Phytic Acid; Pyridines; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Structure-Activity Relationship; Sulfhydryl Reagents | 1989 |
Intersubunit fluorescence energy transfer in human factor VIII.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Cysteine; Disulfides; Energy Transfer; Factor VIII; Fluorescent Dyes; Humans; Lysine; Molecular Sequence Data; Spectrometry, Fluorescence; Sulfhydryl Compounds | 1989 |
Thialysine utilization for protein synthesis by an exponentially growing E. coli culture.
Topics: Aspartate Kinase; Bacterial Proteins; Cysteine; Escherichia coli; Lysine; Phosphotransferases; Time Factors | 1989 |
Biochemical characterization of a thialysine-resistant clone of CHO cells.
Topics: Adenosine Triphosphate; Animals; Arginine; Biological Transport; Cricetinae; Cysteine; Diphosphates; Drug Resistance; Kinetics; Lysine; Lysine-tRNA Ligase; Organoselenium Compounds; Selenium | 1987 |
The secondary structure of apolipoproteins in human HDL3 particles after chemical modification of their tyrosine, lysine, cysteine or arginine residues. A Fourier transform infrared spectroscopy study.
Topics: Acylation; Alkylation; Amino Acids; Apolipoproteins E; Arginine; Cyclohexanones; Cysteine; Fourier Analysis; Humans; Lipoproteins, HDL; Low Density Lipoprotein Receptor-Related Protein-1; Lysine; Oxidation-Reduction; Protein Conformation; Receptors, Cell Surface; Spectrophotometry, Infrared; Tetranitromethane; Tyrosine | 1988 |
Aspartokinase III repression in a thialysine-resistant mutant of E. coli.
Topics: Aspartate Kinase; Biological Transport, Active; Cysteine; Drug Resistance, Microbial; Escherichia coli; Kinetics; Lysine; Lysine-tRNA Ligase; Mutation; Phosphotransferases | 1988 |
Effect of chemical modifications on the K99 and K88ab fibrillar adhesins of Escherichia coli.
Topics: Adhesins, Escherichia coli; Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cysteine; Fimbriae, Bacterial; Lysine; Tyrosine | 1985 |
Chemical modification of NADPH-cytochrome P-450 reductase. Presence of a lysine residue in the rat hepatic enzyme as the recognition site of 2'-phosphate moiety of the cofactor.
Topics: Animals; Binding Sites; Coenzymes; Cysteine; Cytochrome c Group; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Liver; Lysine; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Phosphates; Rats; Trinitrobenzenesulfonic Acid | 1986 |
Inactivation of metalloenzymes by lysinoalanine, phenylethylaminoalanine, alkali-treated food proteins, and sulfur amino acids.
Topics: Alkaline Phosphatase; Carboxypeptidases; Carboxypeptidases A; Catechol Oxidase; Cysteine; Dietary Proteins; Electron Transport Complex IV; Kinetics; Lysine; Lysinoalanine; Metalloproteins; Phenethylamines; Protein Binding; Protein Hydrolysates | 1986 |
Isolation and properties of a thialysine-resistant clone of CHO cells.
Topics: Animals; Cell Division; Cell Line; Clone Cells; Cricetinae; Cricetulus; Cysteine; Drug Resistance; Female; Lysine; Ovary; Phenotype; Protein Biosynthesis | 1986 |
The increase by spermidine of fidelity of protamine synthesis in a wheat-germ cell-free system.
Topics: Arginine; Cell-Free System; Centrifugation, Density Gradient; Cysteine; Histidine; Lysine; Peptide Biosynthesis; Protamines; RNA, Messenger; RNA, Transfer, Amino Acyl; Spermidine; Threonine; Triticum | 1986 |
Penicillin-binding site on the Escherichia coli cell envelope.
Topics: Bacterial Proteins; Carboxypeptidases; Carrier Proteins; Cysteine; Escherichia coli; Hexosyltransferases; Hydrogen-Ion Concentration; Lysine; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases | 1986 |
Effects of selenalysine on thialysine resistant CHO cells.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Clone Cells; Culture Media; Cysteine; Drug Resistance; Lysine; Organoselenium Compounds; Protein Biosynthesis; Selenium | 1986 |
Glucose represses formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine and isopenicillin N synthase but not penicillin acyltransferase in Penicillium chrysogenum.
Topics: 2-Aminoadipic Acid; Acyltransferases; Bacterial Proteins; Cysteine; Enzyme Repression; Enzymes; Glucose; Lysine; Oligopeptides; Oxidoreductases; Oxo-Acid-Lyases; Penicillin-Binding Proteins; Penicillium; Penicillium chrysogenum; Peptide Synthases; Saccharopine Dehydrogenases; Valine | 1986 |
Amino acid requirements of Eikenella corrodens.
Topics: Amino Acids; Arginine; Bacteroides; Culture Media; Cysteine; Eikenella corrodens; Histidine; Humans; Lysine; Proline; Tyrosine | 1986 |
O6-methylguanine-DNA methyltransferase and alkylation of liver DNA in mice exposed to dimethylnitrosamine during dietary deficiency of essential amino acids.
Topics: Amino Acids; Animals; Cysteine; Diet; Dimethylnitrosamine; DNA; DNA Damage; DNA Repair; Liver; Lysine; Methionine; Methylation; Methyltransferases; Mice; O(6)-Methylguanine-DNA Methyltransferase | 1987 |
Inactivation of bee venom phospholipase A2 by manoalide. A model based on the reactivity of manoalide with amino acids and peptide sequences.
Topics: Amino Acids; Cysteine; Glutathione; Hydrogen-Ion Concentration; Kinetics; Lysine; Oligopeptides; Phospholipases; Phospholipases A; Phospholipases A2; Spectrophotometry; Terpenes; Tryptophan | 1987 |
Intracellular transport of thialysine and selenalysine in CHO cells.
Topics: Amino Acids; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Cysteine; Female; Kinetics; Lysine; Organoselenium Compounds; Ovary; Selenium | 1987 |
Spatial relationship between the nucleotide-binding site, Lys-61 and Cys-374 in actin and a conformational change induced by myosin subfragment-1 binding.
Topics: Actins; Affinity Labels; Binding Sites; Cysteine; Energy Transfer; Lysine; Myosin Subfragments; Myosins; Peptide Fragments; Phalloidine; Polymers; Protein Conformation; Spectrometry, Fluorescence | 1987 |
Construction of a model for the aggregation and cross-linking region (7S domain) of type IV collagen based upon an evaluation of the primary structure of the alpha 1 and alpha 2 chains in this region.
Topics: Amino Acid Sequence; Amino Acids; Basement Membrane; Binding Sites; Collagen; Computer Simulation; Cysteine; Humans; Hydrolysis; Lysine; Peptide Fragments; Peptide Hydrolases; Placenta; Protein Conformation | 1987 |
Three possible disulfides in the acetylcholine receptor alpha-subunit.
Topics: Animals; Borohydrides; Bungarotoxins; Cysteine; Disulfides; Ethylmaleimide; Lysine; Macromolecular Substances; Maleimides; Peptide Mapping; Receptors, Cholinergic; Serine Endopeptidases; Torpedo | 1988 |
Degradation of thialysine- or selenalysine-containing abnormal proteins in CHO cells.
Topics: Amino Acids; Animals; Cells, Cultured; Cricetinae; Cricetulus; Cysteine; Isoleucine; Leucine; Lysine; Organoselenium Compounds; Protein Biosynthesis; Protein Hydrolysates; Proteins; Selenium | 1987 |
NBD-Cl modification of essential residues in mitochondrial nicotinamide nucleotide transhydrogenase from bovine heart.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; Kinetics; Lysine; Mitochondria, Heart; NAD; NADH, NADPH Oxidoreductases; NADP; NADP Transhydrogenases; Oxadiazoles; Photochemistry; Spectrometry, Fluorescence; Spectrophotometry; Sulfhydryl Compounds | 1988 |
Chemical modification of lysine residues at active-site of human placental estradiol 17 beta-dehydrogenase.
Topics: 17-Hydroxysteroid Dehydrogenases; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Enzyme Activation; Estradiol Dehydrogenases; Female; Humans; Lysine; Placenta; Pregnancy; Structure-Activity Relationship; Sulfhydryl Reagents; Trinitrobenzenesulfonic Acid | 1988 |
Recognition of aminoethylhomocysteine and aminopropylcysteine by aminoacid transport systems and aminoacyl tRNA synthetases.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Arginine; Binding Sites; Biological Transport; Cricetinae; Cricetulus; Cysteine; Escherichia coli; Homocysteine; Lysine; Structure-Activity Relationship | 1987 |
Solid-state NMR observation of cysteine and lysine Michael adducts of inactivated estradiol dehydrogenase.
Topics: 17-Hydroxysteroid Dehydrogenases; Chemical Phenomena; Chemistry; Cysteine; Enzyme Activation; Estradiol Dehydrogenases; Estrenes; Freeze Drying; Lysine; Magnetic Resonance Spectroscopy; Magnetics; Pronase; Secosteroids | 1988 |
Fluorescence resonance energy transfer studies on the proximity between lysine-107 and cysteine-239 in rabbit muscle aldolase.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cysteine; Energy Transfer; Fructose-Bisphosphate Aldolase; Lysine; Muscles; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Pyridoxamine; Rabbits; Spectrometry, Fluorescence | 1988 |
Degradation of thialysine- or selenalysine-containing abnormal proteins in E. coli.
Topics: Bacterial Proteins; Cysteine; Escherichia coli; Leucine; Lysine; Organoselenium Compounds; Selenium | 1988 |
Inactivation of yeast hexokinase by o-phthalaldehyde: evidence for the presence of a cysteine and a lysine at or near the active site.
Topics: Aldehydes; Binding Sites; Chelating Agents; Chemical Phenomena; Chemistry; Cysteine; Hexokinase; Kinetics; Lysine; Nucleosides; Nucleotides; o-Phthalaldehyde; Pyridoxal Phosphate; Saccharomyces cerevisiae; Structure-Activity Relationship | 1988 |
Fluorescence quenching studies of fluorescein attached to Lys-61 or Cys-374 in actin: effects of polymerization, myosin subfragment-1 binding, and tropomyosin-troponin binding.
Topics: Actins; Cysteine; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescence; Lysine; Myosin Subfragments; Myosins; Peptide Fragments; Polymers; Protein Binding; Solvents; Spectrometry, Fluorescence; Thiocyanates; Tropomyosin; Troponin; Viscosity | 1988 |
Utilization of lysine analogs by a lysine-requiring E. coli mutant.
Topics: Cysteine; Escherichia coli; Isoleucine; Kinetics; Leucine; Lysine; Mutation; Organoselenium Compounds; Selenium | 1988 |
Thialysine- and selenalysine-resistance in a E. coli mutant.
Topics: Aspartate Kinase; Cysteine; Drug Resistance, Microbial; Enzyme Repression; Escherichia coli; Kinetics; Lysine; Lysine-tRNA Ligase; Mutation; Organoselenium Compounds; Selenium | 1988 |
Hapten-specific prophylaxis of murine contact sensitivity by DNP-amino acid derivatives.
Topics: Alanine; Amino Acids; Animals; Cell Division; Cysteine; Dermatitis, Contact; Dinitrofluorobenzene; Dinitrophenols; Female; Glycine; Haptens; Immunization, Passive; Lymph Nodes; Lysine; Mice; Mice, Inbred BALB C; Spleen | 1985 |
Nutritional significance of cysteine dioxygenase on the biological evaluation of dietary protein in growing rats.
Topics: Amino Acids, Sulfur; Animals; Brain; Caseins; Cysteine; Cysteine Dioxygenase; Dietary Proteins; Dioxygenases; Glutens; Liver; Lysine; Methionine; Myocardium; Nutritional Physiological Phenomena; Oxygenases; Plant Proteins, Dietary; Rats; Soybean Proteins; Taurine | 1985 |
Reactions of proteins with oxidizing lipids. 2. Influence on protein quality and on the bioavailability of lysine, methionine, cyst(e)ine and tryptophan as measured in rat assays.
Topics: Animals; Biological Availability; Body Weight; Cysteine; Dietary Proteins; Lipid Metabolism; Lysine; Male; Methionine; Nitrogen; Oxidation-Reduction; Rats; Rats, Inbred Strains; Tryptophan | 1985 |
Effects of thialysine on CHO cells growth.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cysteine; DNA Replication; Female; Kinetics; Lysine; Ovary; Protein Biosynthesis; Transcription, Genetic | 1985 |
Isolation of two trypsin inhibitors from resting seeds of the white bush (Cucurbita pepo var. patissonina) and their properties.
Topics: Amino Acids; Chromatography; Cysteine; Electrophoresis, Polyacrylamide Gel; Lysine; Molecular Weight; Plant Proteins; Plants; Protease Inhibitors; Seeds; Streptomyces griseus; Trypsin Inhibitors | 1985 |
Axonal transport of proteins in retinal ganglion cells. Amino acid incorporation into rapidly transported proteins and distribution of radioactivity to the lateral geniculate body and the superior colliculus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Axonal Transport; Cysteine; Female; Geniculate Bodies; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Nerve Tissue Proteins; Optic Nerve; Phenylalanine; Proline; Rabbits; Retina; Superior Colliculi; Tritium; Tryptophan | 1972 |
The antibody binding site. Labelling of a specific antibody against the photo-precursor of an aryl nitrene.
Topics: Alanine; Amino Acids; Aminopeptidases; Animals; Antibodies; Arginine; Binding Sites; Blood Protein Electrophoresis; Cattle; Cysteine; Epitopes; gamma-Globulins; Glycine; Haptens; Iodoacetates; Lysine; Nitrophenols; Peptides; Photochemistry; Photolysis; Rabbits; Serum Albumin; Tritium; Trypsin | 1972 |
Formation of C3a and C5a anaphylatoxins in whole human serum after inhibition of the anaphylatoxin inactivator.
Topics: Adsorption; Aminocaproates; Anaphylaxis; Animals; Antigen-Antibody Complex; Arginine; Chromatography; Chromatography, Gel; Complement Inactivator Proteins; Complement System Proteins; Cysteine; Guinea Pigs; Histamine Release; Humans; Ileum; Immune Sera; Immunoelectrophoresis; In Vitro Techniques; Lysine; Methylcellulose; Molecular Weight; Phagocytosis; Rabbits; Skin Tests; Toxins, Biological; Yeasts | 1973 |
Histochemical studies on calcified tissues. I. Amino acid histochemistry of foetal calf and human enamel matrix.
Topics: Amino Acids; Animals; Arginine; Carboxylic Acids; Cattle; Collagen; Cysteine; Dental Enamel; Histidine; Histocytochemistry; Humans; Keratins; Lysine; Microscopy, Phase-Contrast; Odontogenesis; Staining and Labeling; Tooth Germ; Tryptophan; Tyrosine | 1974 |
Histochemical studies on calcified tissues. II. Amino acid histochemistry of developing dentine and bone.
Topics: Amino Acids; Animals; Arginine; Bone Matrix; Calcification, Physiologic; Cattle; Cysteine; Dentin; Dentinogenesis; Histidine; Histocytochemistry; Incisor; Lysine; Odontogenesis; Osteogenesis; Staining and Labeling; Sulfhydryl Compounds; Tooth Germ; Tryptophan; Tyrosine | 1974 |
Triphosphopyridine nucleotide specific isocitrate dehydrogenase from Azotobacter vinelandii. Alkylation of a specific methionine residue and amino acid sequence of the peptide containing this residue.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Cysteine; Iodoacetates; Isocitrate Dehydrogenase; Lysine; Malates; Methionine; NADP; Peptide Fragments; Protein Denaturation; Structure-Activity Relationship; Thiocyanates; Tritium; Trypsin; Urea | 1974 |
The position of various cleavages of rabbit immunoglobulin G.
Topics: Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Bromine; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyanides; Cysteine; gamma-Globulins; Glutamates; Leucine; Lysine; Pepsin A; Proline; Rabbits; Serine; Sulfhydryl Compounds; Threonine; Trypsin | 1968 |
The specific cleavage of immunoglobulin polypeptide chains at cysteinyl residues.
Topics: Alkylation; Amino Acids; Anhydrides; Animals; Arginine; Bence Jones Protein; Bicarbonates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyclohexanes; Cysteine; gamma-Globulins; Humans; Ketones; Lysine; Methods; Mice; Peptides; Quaternary Ammonium Compounds; Species Specificity; Succinates; Sulfhydryl Compounds; Sulfur; Thiocyanates; Tritium; Trypsin; Urea | 1968 |
The interaction of gamma-globulin with lipids.
Topics: Animals; Arginine; Bence Jones Protein; Benzoates; Cattle; Chickens; Cholesterol; Cysteine; gamma-Globulins; Histidine; Horses; Humans; Hydrogen-Ion Concentration; Iodoacetates; Lysine; Mercury; Methionine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Binding; Rabbits; Sodium Chloride; Sphingomyelins; Swine; Time Factors; Tyrosine | 1968 |
Characterization of phycocyanin from Chromonas species.
Topics: Amino Acids; Ammonium Sulfate; Bile Pigments; Chromatography, Gel; Circular Dichroism; Cyanobacteria; Cysteine; Electrophoresis, Polyacrylamide Gel; Eukaryota; Lysine; Macromolecular Substances; Mathematics; Peptides; Plant Proteins; Rhodophyta; Serine; Sodium Dodecyl Sulfate; Species Specificity; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Ultracentrifugation | 1973 |
The designation of the major guinea-pig neural lobe protein as a neurophysin.
Topics: Animals; Antigens; Biological Assay; Cross Reactions; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Glutamine; Glycine; Guinea Pigs; Histidine; Immunodiffusion; Isoleucine; Lysine; Male; Methionine; Molecular Weight; Neurophysins; Pituitary Gland, Posterior; Sulfur Radioisotopes; Tyrosine | 1973 |
Irreversible binding of ethynyl-estradiol metabolites to protein and nucleic acids as catalyzed by rat liver microsomes and mushroom tyrosinase.
Topics: Animals; Binding Sites; Catechol Oxidase; Cysteine; DNA; Estradiol; Ethanolamines; Ethinyl Estradiol; Ethylenediamines; Glutathione; Lysine; Male; Methionine; Microsomes, Liver; Plants; Protein Binding; Proteins; Quinones; Rats; RNA; Tritium | 1974 |
Studies on nitrogen pool of animal tissues. 3. Ox liver and bile. IV. Ox kidney and lung.
Topics: Amino Acids; Animals; Arginine; Autoanalysis; Bile; Cattle; Cysteine; Kidney; Liver; Lung; Lysine; Nitrogen; Urinary Bladder | 1967 |
On the active site of myosin A-adenosine triphosphatase. IX. Chemical modification of the enzyme by monoiodoacetamide.
Topics: Adenosine Triphosphatases; Amides; Animals; Binding Sites; Chloromercuribenzoates; Chromatography; Cysteine; Dextrans; Edetic Acid; Enzyme Activation; Ethylmaleimide; Histidine; Iodoacetates; Lysine; Muscle Proteins; Nitrobenzenes; Rabbits; Sulfonamides; Sulfonic Acids; Toluene; Tyrosine | 1970 |
Supramolecular structure of the rigid layer of the cell wall of Salmonella, Serratia, Proteus, and Pseudomonas fluorescens. Number of lipoprotein molecules in a membrane layer.
Topics: Amino Acids; Arginine; Cell Wall; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Cytoplasm; Detergents; Disaccharides; Endopeptidases; Escherichia coli; Glycine; Glycosaminoglycans; Histidine; Lipoproteins; Lysine; Membranes; Microscopy, Electron; Molecular Weight; Muramidase; Papain; Peptide Hydrolases; Phenylalanine; Polysaccharides, Bacterial; Proline; Proteus; Pseudomonas; Salmonella typhimurium; Serratia marcescens; Sulfuric Acids; Trypsin | 1970 |
Proceedings: Catalysis of the covalent binding of estrogens to macromolecules by liver microsomes as compared with the model enzyme tyrosinase.
Topics: Animals; Basidiomycota; Catalysis; Catechol Oxidase; Cysteine; DNA; Estrogens; Ethinyl Estradiol; In Vitro Techniques; Lysine; Microsomes, Liver; Rats; RNA | 1974 |
Hepatic blood flow changes following intravenous infusion of various single amino acids in dogs. 3.
Topics: Alanine; Amino Acids; Animals; Arginine; Cysteine; Dogs; Electromagnetic Phenomena; Hepatic Artery; Hepatic Veins; Injections, Intravenous; Liver; Liver Circulation; Lysine; Phenylalanine; Portal System; Rheology; Stimulation, Chemical; Threonine; Tryptophan | 1974 |
[Effect of a prolonged treatment by S-carboxy-methyl-cysteine on the disturbances of the pulmonary protein synthesis induced by sulfur dioxide in the rat].
Topics: Administration, Oral; Animals; Carbon Radioisotopes; Carboxylic Acids; Cysteine; Lung; Lysine; Methylation; Mucus; Protein Biosynthesis; Rats; Respiratory System; Sulfur Dioxide; Trachea | 1974 |
L-Lysine dehydrogenase deficiency in a patient with congenital lysine intolerance.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Oxidoreductases; Cysteine; Humans; In Vitro Techniques; Liver; Lysine; NAD | 1966 |
The enzymatic significance of S-acetylation and N-acetylation of 3-phosphoglyceraldehyde dehydrogenase.
Topics: Acetates; Animals; Arsenicals; Autoradiography; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Cyanides; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Lysine; Muscles; NAD; Nitrophenols; Phenylacetates; Rabbits | 1967 |
[On amino acid modifications after high dose irradiation: dipole diffusion of the ESR lines for high radical concentrations].
Topics: Amino Acids; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Glycine; Lysine; Methionine; Radiation Effects | 1966 |
Homocitrate formation in Neurospora crassa. Relation to lysine biosynthesis.
Topics: Acetates; Adenosine Triphosphate; Adipates; Amino Acids; Cell-Free System; Chromatography; Citrates; Coenzyme A; Cysteine; Enzyme Repression; Feedback; Infrared Rays; Ketoglutaric Acids; Lysine; Magnesium; Malates; Mutation; Neurospora; Saccharomyces; Silicon Dioxide; Spectrum Analysis | 1968 |
The divergence in reactivity of aminoacyl transfer ribonucleic acid synthetases of Escherichia coli with hydroxylamine.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Escherichia coli; Glutamates; Glycine; Hydroxylamines; Isoleucine; Kinetics; Leucine; Ligases; Lysine; Methionine; Periodic Acid; Phenylalanine; RNA, Bacterial; RNA, Transfer; Threonine; Tryptophan; Tyrosine | 1968 |
The effects of bound anions on the reactivity of residues in hemerythrin.
Topics: Amino Acid Sequence; Binding Sites; Borates; Carbonates; Chemical Phenomena; Chemistry, Physical; Cysteine; Helminths; Hydrogen-Ion Concentration; Lysine; Nitrates; Perchlorates; Phosphates; Protein Binding; Proteins; Spectrophotometry; Succinates; Thiocyanates | 1971 |
Glyceraldehyde phosphate dehydrogenase of Escherichia coli. Structural and catalytic properties.
Topics: Acetylesterase; Adenine Nucleotides; Amino Acids; Animals; Arginine; Benzoates; Charcoal; Crystallization; Cysteine; Escherichia coli; Formates; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanidines; Hydrogen-Ion Concentration; Iodoacetates; Lysine; Mercaptoethanol; Molecular Weight; Muscles; NAD; Oxidation-Reduction; Peptides; Protein Denaturation; Rabbits; Spectrophotometry; Sulfhydryl Compounds; Sulfides; Trypsin; Tryptophan; Ultracentrifugation; Ultraviolet Rays | 1971 |
EPR study of Cu(II) complexes of tridentate amino acids.
Topics: Amino Acids; Aminobutyrates; Arginine; Chelating Agents; Chemical Phenomena; Chemistry; Chlorides; Copper; Cysteine; Dicarboxylic Acids; Electron Spin Resonance Spectroscopy; Histidine; Lysine; Methionine; Ornithine; Polyamines; Propionates; Sodium Hydroxide; Time Factors; Tryptophan; Tyrosine | 1971 |
Alterations of free amino acids concentrations in cat brain induced by rapid eye movement sleep deprivation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cats; Caudate Nucleus; Cysteine; Frontal Lobe; Glutamates; Glycine; Hippocampus; Histidine; Lysine; Male; Occipital Lobe; Reticular Formation; Serine; Sleep Deprivation; Sleep, REM; Thalamus; Threonine; Tyrosine | 1971 |
Mutations that affect antibiotic synthesis by Cephalosporium acremonium.
Topics: Acremonium; Adipates; Biological Assay; Carbon Isotopes; Cephalosporins; Chromatography, Paper; Culture Media; Cysteine; Lactams; Lysine; Mutation; Penicillanic Acid; Penicillins; Peptide Biosynthesis; Phenotype; Pipecolic Acids; Time Factors; Valine | 1972 |
Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants and analysis of the response by use of mutants.
Topics: Acetates; Adenosine Monophosphate; Ammonia; Ammonium Chloride; Bromides; Chemotaxis; Chlorides; Cyclic AMP; Cyclic GMP; Cysteine; Histidine; Hydrogen-Ion Concentration; Iodides; Lithium; Lysine; Magnesium; Mutation; Nematoda; Potassium; Sodium | 1973 |
[Obtaining regulation mutants from the biosynthesis pathway of lysine in a strain of Corynebacterium resistant to lysine analogues].
Topics: Aspartic Acid; Carbon; Corynebacterium; Cysteine; Hydro-Lyases; In Vitro Techniques; Lysine; Mutation; Nitrogen; Phosphotransferases; Picolinic Acids; Threonine | 1973 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. III. Isolation and sequences of peptides containing selectively labeled lysine and cysteine residues.
Topics: Amino Acid Sequence; Amino Acids; Aminopeptidases; Binding Sites; Borohydrides; Carbon Radioisotopes; Carboxypeptidases; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Cysteine; Electrophoresis, Paper; Ethylmaleimide; Glutamate Dehydrogenase; Leucyl Aminopeptidase; Lysine; NAD; Neurospora; Neurospora crassa; Oxidation-Reduction; Papain; Peptide Fragments; Protein Binding; Pyridoxal Phosphate; Thermolysin; Trypsin | 1974 |
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. I. Inhibition by amino acids of the enzymes in threonine biosynthesis.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Brevibacterium; Cysteine; Glutathione; Isoleucine; Lyases; Lysine; Methionine; Phosphotransferases; Serine; Temperature; Threonine | 1968 |
Absorption of some amino acids by the haemoflagellate, Trypanosoma gambiense.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Carbon Isotopes; Cysteine; Glutamates; Glycine; Iodoacetates; Kinetics; Leucine; Lysine; Ornithine; Rats; Serine; Threonine; Trypanosoma brucei gambiense | 1972 |
Quaternary-structure-dependent proton dissociation of tyrosines, lysines and cysteines in human hemoglobin.
Topics: Binding Sites; Carboxyhemoglobin; Chloromercuribenzoates; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Hemoglobins; Humans; Hydrogen-Ion Concentration; Iodoacetates; Kinetics; Lysine; Mathematics; Protein Binding; Protein Conformation; Spectrophotometry; Tyrosine; Ultracentrifugation | 1974 |
The inhibition of aminoacyl-tRNA synthetases by acyl derivatives of amino acids.
Topics: Acylation; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Benzyl Compounds; Carcinoma, Ehrlich Tumor; Cysteine; Glutamates; Liver; Lysine; Mice | 1974 |
Kinetics and mechanism of catalysis by proteolytic enzymes. A comparison of the kinetics of hydrolysis of synthetic substrates by bovine alpha- and beta-trypsin.
Topics: Animals; Arginine; Catalysis; Cattle; Computers; Cysteine; Esters; Guanidines; Kinetics; Lysine; Spectrophotometry; Structure-Activity Relationship; Tosyl Compounds; Trypsin | 1974 |
Atypical pattern of utilization of amino acids for mitochondrial protein synthesis in HeLa cells.
Topics: Amino Acids; Arginine; Chloramphenicol; Cycloheximide; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Emetine; Endoplasmic Reticulum; Female; Glutamine; HeLa Cells; Humans; Leucine; Lysine; Methionine; Mitochondria; Neoplasm Proteins; Phenylalanine; Polyribosomes; Serine; Threonine; Tritium; Tryptophan | 1973 |
Thiosine-resistant mutants of Escherichia coli K-12 with growth-medium-dependent lysl-tRNA synthetase activity. I. Isolation and physiological characterization.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Arginine; Carbon Isotopes; Culture Media; Cysteine; Drug Resistance, Microbial; Drug Stability; Escherichia coli; Ethylamines; Genotype; Glutamates; Kinetics; Lysine; Mutagens; Mutation; Species Specificity; Structure-Activity Relationship; Sulfonic Acids; Temperature; Time Factors | 1972 |
Thiosine-resistant mutants of Escherichia coli K-12 with growth-medium-dependent lysyl-tRNA synthetase activity.II. Evidence for an altered lysyl-tRNA synthetase.
Topics: Amino Acyl-tRNA Synthetases; Chromatography, Gel; Cysteine; Drug Resistance, Microbial; Drug Stability; Escherichia coli; Ethylamines; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Lysine; Macromolecular Substances; Molecular Biology; Molecular Weight; Mutation; Protein Denaturation; Species Specificity; Urea | 1972 |
Uptake of amino acids by actidione-treated yeast cells. IV. Interaction with sugars.
Topics: Amino Acids; Anaerobiosis; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Cycloheximide; Cysteine; Glycine; Leucine; Lysine; Methionine; Monosaccharides; Saccharomyces cerevisiae; Stereoisomerism | 1972 |
Histochemical studies on calcified tissues. 3. Amino acid histochemistry of carious dentine and dentinal reactions to caries.
Topics: Amino Acids; Arginine; Cysteine; Decalcification Technique; Dental Caries; Dentin; Histidine; Histocytochemistry; Humans; Lysine; Tryptophan; Tyrosine | 1974 |
Chemical modifications of Escherichia coli ribosomal proteins S4, S7, and S8 in regard to their capacity for binding 16 S RNA.
Topics: Amino Acids; Bacterial Proteins; Benzoates; Binding Sites; Chromatography, Ion Exchange; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Lysine; Macromolecular Substances; Molecular Weight; Nitro Compounds; Protein Binding; Ribosomes; RNA, Bacterial; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Tyrosine | 1974 |
Effect of carbobenzoxy, phenylacetyl and phenylpropionyl derivatives of amino acids on mammalian and bacterial asparaginase.
Topics: Amino Acids; Animals; Asparaginase; Cysteine; Erwinia; Escherichia coli; Liver; Lysine; Phenylalanine; Rats | 1974 |
Inactivation of papain by S-methylation of its cysteinyl residue with O-methylisourea.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Edetic Acid; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Lysine; Mathematics; Mercaptoethanol; Mercury; Methylation; Methylurea Compounds; Organometallic Compounds; Papain; Sulfhydryl Reagents; Urea | 1972 |
Hyperalimentation in cirrhotic patients.
Topics: Acid-Base Equilibrium; Acidosis; Alanine Transaminase; Alkaline Phosphatase; Amino Acids; Ammonia; Arginine; Carbon Dioxide; Caseins; Catheterization; Cysteine; Diet Therapy; Fibrin; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Liver Cirrhosis; Lysine; Methionine; Parenteral Nutrition; Phenylalanine; Potassium; Sodium; Threonine; Tryptophan | 1972 |
Human carbonic anhydrases. X. Preparation of large peptide fragments of carbonic anhydrase B used for sequence studies.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Carbonic Anhydrases; Chromatography, Gel; Cyanogen Bromide; Cysteine; Erythrocytes; Freeze Drying; Guanidines; Humans; Hydrogen-Ion Concentration; Lysine; Methionine; Peptides; Phenylalanine; Solubility; Spectrophotometry, Ultraviolet; Trypsin; Tryptophan; Tyrosine | 1973 |
Human carbonic anhydrases. XI. The complete primary structure of carbonic anhydrase B.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Autoanalysis; Carbonic Anhydrases; Carboxypeptidases; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Cyanogen Bromide; Cysteine; Electrophoresis, Paper; Erythrocytes; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Peptides; Solubility; Sulfhydryl Compounds; Trypsin; Tryptophan | 1973 |
Naturally occurring crystals in the potato: isolation and identification as a protein.
Topics: Amino Acids; Centrifugation; Chromatography, Gel; Chymotrypsin; Crystallization; Cysteine; Cystine; Dialysis; Electrophoresis, Disc; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Lysine; Molecular Weight; Peptide Hydrolases; Plant Proteins; Plants; Sodium Dodecyl Sulfate | 1972 |
The chemical composition of wool. XI. Separation and analysis of exocuticle and endocuticle.
Topics: Amino Acids; Animals; Aspartic Acid; Coloring Agents; Cysteine; Cystine; Formates; Histidine; Leucine; Lysine; Methionine; Microscopy, Electron; Phenylalanine; Proline; Pronase; Sheep; Structure-Activity Relationship; Threonine; Tyrosine; Wool | 1972 |
The tubular reabsorption of L-cystine and L-cysteine. A common transport system with L-arginine or not?
Topics: Absorption; Animals; Arginine; Biological Transport, Active; Carbon Isotopes; Cysteine; Cystine; Cystinuria; Glycine; Guanidines; Inulin; Kidney Tubules; Kidney Tubules, Proximal; Lysine; Male; Ornithine; Perfusion; Pimelic Acids; Rats; Tritium | 1972 |
[Biosynthetic precursors of collagen and their transformation in vitro].
Topics: Amino Acid Sequence; Animals; Chick Embryo; Chromatography, Gel; Collagen; Cysteine; Extracellular Space; Hydroxylation; In Vitro Techniques; Lysine; Molecular Weight; Polyribosomes; Proline; Protein Binding; Tryptophan | 1972 |
Enhancement of iron absorption from ligated segments of rat intestine by histidine, cysteine, and lysine: effects of removing ionizing groups and of stereoisomerism.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Chelating Agents; Chemical Phenomena; Chemistry; Cysteine; Deamination; Decarboxylation; Duodenum; Histidine; Intestine, Small; Ions; Iron; Iron Isotopes; Ligation; Lysine; Male; Rats; Serine; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds | 1973 |
Cellular accumulation of L-cystine in rat kidney cortex in vivo.
Topics: Animals; Biological Transport; Cysteine; Cystine; Glutathione; Kidney; Kidney Cortex; Ligation; Lysine; Male; Rats; Sulfur Isotopes; Time Factors; Tritium; Ureter | 1973 |
The effect of bifunctional and monofunctional azo-dye reagents upon the oxygen-binding mechanism of human hemoglobin.
Topics: Acetamides; Alkylation; Autoanalysis; Azo Compounds; Chromatography, Ion Exchange; Cysteine; Hemoglobins; Histidine; Humans; Iodoacetates; Kinetics; Lysine; Macromolecular Substances; Oxygen; Oxygen Consumption; Protein Binding; Protein Conformation; Spectrophotometry; Structure-Activity Relationship; Ultracentrifugation | 1973 |
Quantitative effects of nutritional essential amino acid deficiency upon immune responses to tumors in mice.
Topics: Adenocarcinoma; Amino Acids; Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Arginine; Cells, Cultured; Cysteine; Cytotoxicity Tests, Immunologic; Deficiency Diseases; Diet; Histidine; Immunity, Cellular; Isoleucine; Lysine; Male; Mammary Neoplasms, Experimental; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Phenylalanine; Threonine; Time Factors; Tryptophan; Tyrosine; Valine | 1973 |
Affinity labeling of aspartate aminotransferase isozymes by bromopyruvate.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Binding Sites; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Circular Dichroism; Cysteine; Cytoplasm; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lysine; Mitochondria, Muscle; Myocardium; Peptides; Pyruvates; Spectrophotometry, Ultraviolet; Sulfinic Acids; Swine | 1973 |
Intensities and other spectral parameters of infrared amide bands of polypeptides in the beta- and random forms.
Topics: Alanine; Amides; Amino Acid Sequence; Bombyx; Chemical Phenomena; Chemistry; Cysteine; Fibroins; Glycine; Lysine; Peptides; Polymers; Spectrophotometry, Infrared | 1973 |
The substrate analog, bromopyruvate, as a bridging agent for the active site of 2-keto-3-deoxy-6-phosphogluconic aldolase. Chemical evidence for a carboxylate adjacent to the Schiff's base-forming lysine.
Topics: Aldehyde-Lyases; Alkylation; Amines; Amino Acids; Binding Sites; Borohydrides; Bromine; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Cysteine; Drug Stability; Gluconates; Lysine; Osmolar Concentration; Oxidation-Reduction; Protein Binding; Protein Conformation; Pseudomonas; Pyruvates; Schiff Bases; Sodium Chloride; Structure-Activity Relationship; Sulfur Radioisotopes; Tritium | 1973 |
Influence of various ligands on the desensitization of phosphorylase b by dinitrophenylation.
Topics: Adenosine Monophosphate; Animals; Binding Sites; Cysteine; Fluorine; Glucosephosphates; Kinetics; Ligands; Lysine; Muscles; Nitrobenzenes; Phosphates; Phosphorylases; Protein Binding; Rabbits | 1973 |
Circular dichroism and optical rotatory dispersion of proteins and polypeptides.
Topics: Animals; Cetacea; Circular Dichroism; Cysteine; Evaluation Studies as Topic; Glutamates; Hydrogen-Ion Concentration; Light; Lysine; Mathematics; Methods; Molecular Weight; Myoglobin; Optical Rotatory Dispersion; Peptides; Protein Conformation; Proteins; Scattering, Radiation; Spectrophotometry; Spectrophotometry, Ultraviolet | 1973 |
Proteins lacking certain amino acids.
Topics: Arginine; Aspartic Acid; Cysteine; Glutamates; Histidine; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Tryptophan; Tyrosine; Valine | 1974 |
Specificity of amino acid transport in Trypanosoma equiperdum.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Binding Sites; Biological Transport; Carbon Radioisotopes; Culture Media; Cysteine; Diffusion; Glucose; Glutamates; Histidine; Lysine; Phenylalanine; Stimulation, Chemical; Trypanosoma | 1974 |
Antimetabolites produced by microorganisms. X. L-2-amino-4-(2-aminoethoxy)-trans-3-butenoic acid.
Topics: Antimetabolites; Arginine; Cysteine; Lysine; Ornithine; Streptomyces | 1974 |
Enzymatic N-acetylation of lysine analogs. Purification and properties of acetyl coenzyme A:S-(beta-aminoethyl)-L-cysteine omega-N-acetyltransferase.
Topics: Acetyltransferases; Benzyl Compounds; Butyrates; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Coenzyme A; Cysteine; Drug Stability; Electrophoresis, Disc; Enterobacter; Ethylamines; Hydrogen-Ion Concentration; Isomerases; Kinetics; Lysine; Molecular Weight; Ornithine; Propionates; Structure-Activity Relationship; Sulfur Radioisotopes; Time Factors | 1974 |
Guanidination of lysine-15 in the active site of the basic pancreatic trypsin inhibitor. Implications for complex formation with trypsin and chymotrypsin.
Topics: Acetates; Animals; Binding Sites; Carbon Radioisotopes; Cattle; Chymotrypsin; Cysteine; Guanidines; Kinetics; Lysine; Mathematics; Oxidation-Reduction; Pancreas; Protein Binding; Structure-Activity Relationship; Trypsin; Trypsin Inhibitors | 1974 |
Argenine decarboxylase from Escherichia coli. I. Purification and specificity for substrates and coenzyme.
Topics: Arginine; Binding Sites; Canavanine; Carboxy-Lyases; Chemical Precipitation; Chromatography, Ion Exchange; Crystallization; Cysteine; Dialysis; Electrophoresis, Disc; Escherichia coli; Guanidines; Hydrogen-Ion Concentration; Kinetics; Lysine; Protein Binding; Pyridoxal Phosphate; Spectrum Analysis; Temperature; Ultracentrifugation; Ultraviolet Rays | 1968 |
Bovine pepsinogen and pepsin. I. Isolation, purification, and some properties of the pepsinogen.
Topics: Abomasum; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Disc; Enzyme Precursors; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Molecular Weight; Pepsin A; Proline; Swine; Tryptophan; Ultracentrifugation | 1968 |
[Investigation on resorption of the endolymph in the inner ear of the guinea pig. II. Experiments with radioactive labeled substances and autoradiographic evaluation].
Topics: Animals; Autoradiography; Carbon Isotopes; Cysteine; Ear, Inner; Glucose; Guinea Pigs; Histological Techniques; Injections; Labyrinthine Fluids; Lysine; Molecular Weight; Photometry; Proteins; Tritium | 1969 |
Prolonged survival of glutaraldehyde-treated skin homografts.
Topics: Alanine; Aldehydes; Animals; Binding Sites; Cysteine; Female; Glutarates; Graft Rejection; Lysine; Mice; Peptides; Phenylalanine; Polymers; Skin; Skin Transplantation; Time Factors; Transplantation Immunology; Transplantation, Homologous | 1971 |
Fractionation of the nonpolar transfer ribonucleic acids from rat liver, yeast, and Escherichia coli by partition chromatography.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Chromatography, Gel; Cysteine; Escherichia coli; Genetic Code; Glutamates; Leucine; Liver; Lysine; Methionine; Nucleosides; Phenylalanine; Rats; RNA, Transfer; Saccharomyces; Serine; Species Specificity; Spectrophotometry; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
RNA codons and protein synthesis. 15. Dissimilar responses of mammalian and bacterial transfer RNA fractions to messenger RNA codons.
Topics: Acylation; Amino Acid Sequence; Animals; Arginine; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Genetic Code; Genetics, Microbial; Guinea Pigs; Isoleucine; Liver; Lysine; Methionine; Molecular Biology; Protein Binding; Protein Biosynthesis; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine; Tritium | 1968 |
Regulation of tryptophanase formation in Escherichia coli.
Topics: Alanine; Amino Acids; Culture Media; Cysteine; Enzyme Activation; Escherichia coli; Glycine; Homoserine; Lysine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenylalanine; Proteins; Serine; Time Factors | 1971 |
Reaction of the subunit of the Escherichia coli tryptophan synthetase with 1,5-difluoro-2,4-dinitrobenzene.
Topics: Amino Acid Sequence; Amino Acids; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Escherichia coli; Fluorine; Glycerophosphates; Hydro-Lyases; Indoles; Kinetics; Lysine; Macromolecular Substances; Molecular Weight; Nitrobenzenes; Peptides; Serine; Spectrophotometry; Trypsin; Ultraviolet Rays | 1971 |
Uptake of amino acids by actidione-treated yeast cells. I. Specificity of carriers.
Topics: Amino Acids; Arginine; Aspartic Acid; Binding Sites; Biological Transport; Carrier Proteins; Cell Membrane; Cycloheximide; Cysteine; Glutamates; Glycine; Histidine; Kinetics; Leucine; Lysine; Methionine; Proline; Protein Biosynthesis; Saccharomyces; Saccharomyces cerevisiae | 1971 |
Studies on the biosynthesis of biotin. Production of biotin and biotin-like compounds by a pseudomonad.
Topics: Amino Acids; Biotin; Chromatography, Paper; Culture Media; Cysteine; Cystine; In Vitro Techniques; Lysine; Malonates; Pimelic Acids; Pseudomonas aeruginosa | 1965 |
Hydrolysis of synthetic esters by the antibacterial agent in serum.
Topics: Acetates; Acetylcholine; Blood; Blood Bactericidal Activity; Calcium Chloride; Chemical Phenomena; Chemistry; Cysteine; Edetic Acid; Esterases; Ethylenes; Lysine; Magnesium; Mercury; Nitrophenols; Physostigmine; Quinine; Staphylococcus; Stearic Acids; Triacetin; Triolein; Zinc | 1966 |
A comparative study of proteolytic activities in the venoms of some North American snakes.
Topics: Animals; Chloromercuribenzoates; Cysteine; Edetic Acid; Enzymes; Glutathione; In Vitro Techniques; Lysine; Peptide Hydrolases; Phenanthrolines; Physiology, Comparative; Snakes; Thioglycolates; Tyrosine; Venoms | 1966 |
A peptidase (aminopeptidase B) from cat and guinea pig liver selective for N-terminal arginine and lysine residues. II. Modifier characteristics and kinetic studies.
Topics: Amides; Aminopeptidases; Animals; Arginine; Cadmium; Cats; Chlorides; Chloromercuribenzoates; Cyanides; Cysteine; Edetic Acid; Guinea Pigs; In Vitro Techniques; Isoflurophate; Kinetics; Lead; Liver; Lysine; Mercaptoethanol; Mercury; Methylene Blue; Naphthalenes; Phenanthrolines; Phosphates; Quinolines; Rats | 1966 |
o-Quinones formed in plant extracts. Their reactions with amino acids and peptides.
Topics: Amino Acids; Catechol Oxidase; Chemical Phenomena; Chemistry; Chlorogenic Acid; Cinnamates; Color; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Manometry; Nicotiana; Oxygen Consumption; Peptides; Plant Extracts; Plants; Plants, Toxic; Proline; Quinones; Spectrophotometry; Time Factors; Tryptophan | 1969 |
Properties of flagellin from Bacillus megaterium KM and its association with the cytoplasmic membrane.
Topics: Amino Acids; Bacillus megaterium; Bacterial Proteins; Bile Acids and Salts; Chemical Precipitation; Cysteine; Cystine; Cytoplasm; Detergents; Electrophoresis; Flagella; Hydrogen-Ion Concentration; Lysine; Membranes; Molecular Weight; Quaternary Ammonium Compounds; Sulfates; Sulfuric Acids; Tryptophan | 1970 |
Enzymic reduction of the C-terminal dehydroalanyl-lysine sequence in nisin.
Topics: Alanine; Anti-Bacterial Agents; Bacillus cereus; Binding Sites; Cysteine; Lysine; Oxidoreductases; Peptides | 1970 |
Microfilaments from amoeba proteins.
Topics: Amino Acids; Amoeba; Animals; Arginine; Cysteine; Dialysis; DNA; Edetic Acid; Electrophoresis, Disc; Glucose; Glutamates; Histocytochemistry; Lysine; Microscopy, Electron; Microtubules; Molecular Weight; Movement; Phospholipids; Potassium Chloride; RNA; Ultracentrifugation | 1971 |
Partial purification, specificity and mechanism of action of the nisin-inactivating enzyme from Bacillus cereus.
Topics: Alanine; Anti-Bacterial Agents; Bacillus cereus; Buffers; Carbon Isotopes; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Gel; Cysteine; Drug Stability; Electrophoresis; Erythromycin; Hot Temperature; Hydrolysis; Kinetics; Lysine; Neomycin; Oxidoreductases; Penicillin G; Peptides; Stereoisomerism; Streptomycin; Tetracycline | 1971 |
Demonstration of a simple method for reducing losses of tryptic peptides during automated sequencing.
Topics: Amino Acid Sequence; Aniline Compounds; Autoanalysis; Carbon Isotopes; Cysteine; Hydantoins; Immunoglobulins; Lysine; Methods; Peptides; Sulfides; Sulfonic Acids; Thiocyanates; Trypsin | 1972 |
Trypsin-pancreatic trypsin inhibitor association. Dynamics of the interaction and role of disulfide bridges.
Topics: Acetamides; Alkylation; Aspartic Acid; Binding Sites; Borohydrides; Carbon Isotopes; Chromatography, Gel; Cysteine; Disulfides; Half-Life; Hydrogen-Ion Concentration; Imines; Iodoacetates; Kinetics; Lysine; Mathematics; Models, Chemical; Oxidation-Reduction; Pancreas; Protein Binding; Temperature; Trypsin; Trypsin Inhibitors; Trypsinogen | 1972 |
Structural studies of calf thymus F3 histone. I. Occurrence of cysteine, phosphoserine, and epsilon-N-acetyllysine in cyanogen bromide peptides.
Topics: Acetates; Acylation; Amino Acids; Animals; Carbon Isotopes; Cattle; Cell Nucleus; Chromatography, Gel; Cyanogen Bromide; Cysteine; Electrophoresis; Histones; Isotope Labeling; Lysine; Phosphates; Phosphopeptides; Phosphoric Acids; Phosphorus Isotopes; Serine; Thymus Gland | 1972 |
Chemical modification of the high-affinity bilirubin-binding site of human-serum albumin.
Topics: Acylation; Arginine; Aspirin; Bilirubin; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Electrophoresis; Histidine; Humans; Lysine; Protein Binding; Protein Conformation; Serum Albumin; Tryptophan; Tyrosine | 1972 |
Potential production and detoxification of penicillic acid in mold-fermented sausage (salami).
Topics: Alkylation; Animals; Arginine; Birds; Caproates; Chick Embryo; Culture Media; Cysteine; Female; Fermentation; Food Contamination; Food Microbiology; Glutathione; Histidine; Lysine; Male; Meat; Mice; Mice, Inbred Strains; Mycotoxins; Penicillium; Rabbits; Skin Tests; Time Factors | 1972 |
New protein reagents. I. Ethyl chloroacetimidate, its properties and its reaction with ribonuclease.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Thin Layer; Cysteine; Esters; Glycine; Histidine; Hydrolysis; Imidoesters; Imines; Indicators and Reagents; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Pancreas; Ribonucleases; Sulfhydryl Compounds | 1972 |
The complete amino-acid sequence of guinea-pig -lactalbumin.
Topics: Albumins; Alkylation; Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Cyanogen Bromide; Cysteine; Guinea Pigs; Lysine; Peptides; Thermolysin; Trypsin | 1972 |
[Histochemical studies on female genital organs during fetal development. V. Protein histochemistry of the human ovary].
Topics: Amino Acids; Cysteine; Cystine; Embryo, Mammalian; Epithelial Cells; Epithelium; Female; Fetus; Gestational Age; Histidine; Histocytochemistry; Humans; Hydroxylysine; Infant, Newborn; Lysine; Ovarian Follicle; Ovary; Pregnancy; Proteins; Tryptophan | 1972 |
[Histochemical studies on female genital organs during fetal development. VI. Protein histochemistry of the uterine tubes].
Topics: Arginine; Cysteine; Cystine; Epithelial Cells; Epithelium; Fallopian Tubes; Female; Fetus; Gestational Age; Histidine; Histocytochemistry; Humans; Hydroxylysine; Lysine; Pregnancy; Proteins; Tryptophan; Tyrosine | 1972 |
The primary structure of the porcine pancreatic secretory trypsin inhibitor. I. Amino acid sequence of the reduced S-aminoethylated protein.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Anhydrides; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Hydrogen-Ion Concentration; Kinetics; Lysine; Maleates; Oxidation-Reduction; Pancreas; Peptides; Species Specificity; Swine; Trypsin; Trypsin Inhibitors | 1971 |
The long-term effects of laminitis in dairy cows.
Topics: Amino Acids; Animals; Cattle; Cattle Diseases; Cysteine; Dairying; Female; Hoof and Claw; Lysine; Methionine; Water | 1971 |
Evidence on erythrocyte aminopeptidase B.
Topics: Aminopeptidases; Animals; Arginine; Borates; Chloromercuribenzoates; Cysteine; Dithiothreitol; Drug Stability; Electrophoresis, Disc; Enzyme Activation; Erythrocytes; Ethylmaleimide; Hot Temperature; Isoenzymes; Kinetics; Liver; Lysine; Mathematics; Methylene Blue; Naphthalenes; Phosphates; Photolysis; Radiation Effects; Rats; Sodium Chloride | 1971 |
[Modification of aminoaciduria in the rat after administration of cycloleucine: comparison with human cystinuria].
Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Chromatography, Ion Exchange; Chromatography, Paper; Cyclopentanes; Cysteine; Cystine; Cystinuria; Diet; Disulfides; Diuresis; Electrophoresis; Homocysteine; Injections, Intraperitoneal; Lysine; Male; Metabolism; Ornithine; Paper; Rats; Time Factors | 1971 |
[Histochemical studies of female genitalia during fetal development. IV. Protein histochemistry of the uterus].
Topics: Alloxan; Amino Acids; Arginine; Cervix Uteri; Cysteine; Cystine; Cytoplasm; Female; Fetus; Gestational Age; Histidine; Histocytochemistry; Humans; Hydroxylysine; Imidazoles; Lysine; Nitrobenzenes; Proteins; Schiff Bases; Sulfhydryl Compounds; Tetrazolium Salts; Tryptophan; Tyrosine; Uterus | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Amino- and carboxyl-terminal amino acid sequences of the Peptostreptococcus eisdenii and Clostridium pasteurianum flavodoxins.
Topics: Alanine; Alkylation; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Carboxypeptidases; Chromatography, Gas; Chromatography, Thin Layer; Clostridium; Cysteine; Desulfovibrio; Flavin Mononucleotide; Flavoproteins; Hydrazines; Kinetics; Leucine; Lysine; Molecular Weight; Peptostreptococcus; Protein Binding; Species Specificity; Structure-Activity Relationship; Valine | 1971 |
Activity and regulation of an acidic amino acid permease of Aspergillus nidulans.
Topics: Ammonia; Asparagine; Aspartic Acid; Aspergillus; Cycloheximide; Cysteine; Glutamates; Glycine; Kinetics; Lysine; Membrane Transport Modulators; Membrane Transport Proteins; Methylamines; Nitrates; Urea | 1971 |
[Dissociation of S- and P-variants of Bacillus brevis var. G.-B. on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Mutation; Nitrogen; Ornithine; Phenylalanine; Serine; Stimulation, Chemical; Threonine; Time Factors; Tryptophan; Valine | 1971 |
Studies on the partial exchange and overall reactions catalyzed by native and modified arginine kinase from Homarus vulgaris muscle.
Topics: Adenine Nucleotides; Alkylation; Animals; Annelida; Arginine; Binding Sites; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Creatine Kinase; Cysteine; Dansyl Compounds; Guanosine Triphosphate; Histidine; Kinetics; L-Lactate Dehydrogenase; Lysine; Muscles; Nephropidae; Phosphotransferases; Protein Binding; Pyruvate Kinase; Rabbits | 1971 |
Group separation: a new method facilitating isolation of peptides from digests of high molecular weight proteins.
Topics: Anhydrides; Arginine; Carboxypeptidases; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Endopeptidases; Histidine; Imides; Lysine; Maleates; Methionine; Methods; Peptides; Phosphoproteins; Proteins; Serine; Trypsin | 1971 |
Hybrid fibrin: proof of the intermolecular nature of - crosslinking units.
Topics: Animals; Binding Sites; Calcium Chloride; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Dialysis; Electrophoresis, Paper; Ethanol; Fibrin; Fibrinogen; Glutamates; Glycine; Humans; Lysine; Methods; Protein Binding; Sulfites; Thrombin; Trypsin; Urea | 1971 |
Luminescence of ribonuclease A.
Topics: Alkylation; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Cold Temperature; Cysteine; Cystine; Dipeptides; Disulfides; Fluorometry; Insulin; Iodoacetates; Kinetics; Luminescent Measurements; Lysine; Mathematics; Mercaptoethanol; Oxidation-Reduction; Pancreas; Peptides; Ribonucleases; Temperature; Tyrosine; Urea | 1971 |
Comparison of invariant residues in the variable and constant regions of human K, human L, and mouse K Bence-Jones proteins.
Topics: Amino Acid Sequence; Animals; Bence Jones Protein; Cysteine; Glutamates; Histidine; Humans; In Vitro Techniques; Leucine; Lysine; Mice; Phenylalanine; Proline; Serine; Tryptophan; Valine | 1967 |
Amino acid fermentation by Fusobacterium nucleatum.
Topics: Amino Acids; Aspartic Acid; Cysteine; Fermentation; Fusobacterium; Gingiva; Glutamates; Glutamine; Histidine; Humans; Lysine; Methionine; Mouth; Serine; Threonine | 1968 |
Amino acid replacements associated with reversion and recombination within a coding unit.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Escherichia coli; Genetic Code; Genetics; Glycine; In Vitro Techniques; Isoleucine; Ligases; Lysine; Mutation; Peptides; Serine; Tryptophan; Valine | 1965 |
[Methods for activating amino acids in tissues of the animal organism].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acids; Animals; Cysteine; Fluorides; Glycine; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Leucine; Ligases; Lysine; Magnesium; Manganese; Methods; Microsomes, Liver; Oxygen Isotopes; Phosphates; Pyrophosphatases; Rats; Spectrum Analysis | 1969 |
[Quantitative differences in nucleic acid and protein metabolism between normal and malignant cell cultures of men and mice].
Topics: Animals; Arginine; Carbon Isotopes; Culture Techniques; Cysteine; DNA; Embryo, Mammalian; Fibroblasts; Glycine; Humans; Kidney; Kidney Neoplasms; Leucine; Lysine; Methionine; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; RNA, Neoplasm; Sarcoma, Experimental; Sulfur Isotopes; Thymidine; Uridine | 1969 |
Amino acid transport into human platelets and subsequent incorporation into protein.
Topics: Amino Acids; Biological Transport; Blood Platelets; Blood Proteins; Carbon Isotopes; Cell Membrane; Cysteine; Fibrin; Fibrinogen; Glutamates; Humans; Leucine; Lysine; Microscopy, Electron; Mitochondria; Proline; Puromycin; Serine; Thrombin; Valine | 1970 |
Purity of amino acids.
Topics: Amino Acids; Arginine; Biological Assay; Cysteine; Histidine; Lysine; Methionine; Pediococcus; Streptococcus; Threonine; Tryptophan; Tyrosine | 1970 |
Lysine 2,3-aminomutase. Purification and properties of a pyridoxal phosphate and S-adenosylmethionine-activated enzyme.
Topics: Acetone; Amino Acids; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Clostridium; Cysteine; Deuterium; Dialysis; Drug Stability; Electrophoresis; Electrophoresis, Disc; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxylamines; Intramolecular Transferases; Iron; Isomerases; Isoniazid; Kinetics; Lysine; Methionine; Methods; Molecular Weight; Nucleosides; Pyridoxal Phosphate; Pyridoxine; Streptomycin; Sulfhydryl Compounds; Temperature; Tritium | 1970 |
[Biosynthesis of gramicidin C on synthetic media with amino acids as the only N source].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrothricin; Valine | 1970 |
Studies on lysine-2,3-aminomutase. Subunit structure and sulfhydryl groups.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Chromatography, Gel; Clostridium; Cysteine; Detergents; Dialysis; Ethylmaleimide; Glutathione; Hydrogen-Ion Concentration; Iodoacetates; Isomerases; Lysine; Methionine; Molecular Weight; Protein Denaturation; Sulfhydryl Compounds; Sulfuric Acids; Urea | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
Amino acid excretion patterns in the offspring of a 'doubly-heterozygous' cystine stone former.
Topics: Alleles; Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Child; Child, Preschool; Chromatography, Paper; Cysteine; Cystinosis; Cystinuria; Female; Ferrocyanides; Heterozygote; Homocysteine; Humans; Lysine; Molecular Biology; Ornithine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
Lysine uptake in cultured Trypanosoma cruzi: interactions of competitive inhibitors.
Topics: Alanine; Animals; Biological Transport; Cysteine; Glycine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Trypanosoma; Tyrosine; Valine | 1970 |
S methylation of thiols by O-methylisourea.
Topics: Acetates; Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Dipeptides; Ethanol; Glycine; Guanidines; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Mercaptoethanol; Methylation; Models, Biological; Sulfhydryl Compounds; Sulfhydryl Reagents; Time Factors; Urea | 1970 |
Constant electrophoretic mobility of the cysteine-containing histone in plants and animals.
Topics: Animals; Anura; Birds; Cattle; Cysteine; Drosophila; Electrophoresis; Erythrocytes; Fishes; Histones; Lysine; Mercaptoethanol; Oxidation-Reduction; Plants; Protein Denaturation; Species Specificity; Thymus Gland | 1970 |
Further studies of the transport of amino acids in rat liver slices.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Cysteine; Cystine; Dinitrophenols; Extracellular Space; Glycine; In Vitro Techniques; Inulin; Iodoacetates; Kinetics; Liver; Lysine; Male; Oxidation-Reduction; Proteins; Rats; Sodium; Sulfur Isotopes; Valine | 1971 |
[Dissociation of R- and P plus-variants of Bacillus brevis var. G.-B. during growth on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Valine | 1971 |
Regional distribution of amino acids in human brain obtained at autopsy.
Topics: Adult; Aged; Amino Acids; Amino Alcohols; Aminobutyrates; Aspartic Acid; Autopsy; Brain Chemistry; Chromatography, Paper; Cysteine; Dipeptides; Electrophoresis; Female; Glutamates; Glutathione; Glycerophosphates; Humans; Lysine; Male; Middle Aged; Phosphatidylethanolamines; Taurine | 1971 |
Optical rotatory dispersion of polypeptides in the near-infrared region.
Topics: Benzene Derivatives; Cysteine; Fibroins; Glutamates; Infrared Rays; Lysine; Optical Rotatory Dispersion; Peptides | 1971 |
Cytochrome c peroxidase. 3. The amino acid composition of cytochrome c peroxidase of Baker's yeast.
Topics: Amino Acids; Ammonia; Chemical Phenomena; Chemistry; Cysteine; Cytochromes; Lysine; Molecular Weight; Peroxidases; Saccharomyces; Tryptophan; Tyrosine | 1967 |
[On the interactions between an active dye and thioenzymes].
Topics: Alanine; Animals; Coloring Agents; Cysteine; Fructose-Bisphosphate Aldolase; Glutathione; Hydrogen-Ion Concentration; Lysine; Muscle Proteins; Papain; Temperature | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
[Isolation, fractionation, sedimentation studies and investigation of characteristic amino acids of ox brain histones].
Topics: Alanine; Amino Acids; Animals; Arginine; Brain Chemistry; Cattle; Cell Nucleus; Chemical Phenomena; Chemistry; Cysteine; Glutamates; Histones; Lysine; Thymus Gland; Ultracentrifugation | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Non-heme iron proteins. V. The amino acid sequence of rubredoxin from Peptostreptococcus elsdenii.
Topics: Amino Acid Sequence; Amino Acids; Bacteria; Bacterial Proteins; Chromatography; Chymotrypsin; Cysteine; Iron; Lysine; Peptococcus; Spectrum Analysis; Trypsin; Tryptophan; Tyrosine | 1968 |
Amino acid requirements for cleavage of the rabbit ovum.
Topics: Amino Acids; Animals; Arginine; Culture Media; Cysteine; Female; Glutamine; In Vitro Techniques; Lysine; Methionine; Ovum; Phenylalanine; Rabbits; Threonine; Tryptophan; Valine | 1968 |
Kinetic studies at high pH of the trypsin-catalyzed hydrolysis of N-alpha-benzoyl derivatives of L-arginamide, L-lysinamide, and S-2-aminoethyl-L-cysteinamide and related compounds.
Topics: Amides; Arginine; Benzene Derivatives; Chromatography, Ion Exchange; Cysteine; Hydrogen-Ion Concentration; Kinetics; Lysine; Spectrophotometry; Trypsin | 1968 |
Dinitrophenylation of glycogen phosphorylase. I. Preparation and properties of active dinitrophenyl derivatives.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Crystallization; Cysteine; Dinitrophenols; Electrophoresis, Disc; Glucosyltransferases; Glycogen; Kinetics; Lysine; Muscles; Rabbits; Spectrophotometry; Sulfhydryl Compounds; Ultracentrifugation | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
The circular dichroism of polypeptide films.
Topics: Acetates; Alkylation; Chemical Phenomena; Chemistry; Cysteine; Lysine; Peptides; Serine; Spectrum Analysis; Valine | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
The excretion of porphyrin-peptide conjugates in porphyria variegata.
Topics: Adolescent; Adult; Aged; Bilirubin; Child; Child, Preschool; Chromatography, Paper; Cysteine; Feces; Female; Hematoporphyrins; Humans; Infant; Lysine; Male; Middle Aged; Peptides; Phenylalanine; Porphyrias; Porphyrins; Pyrroles | 1968 |
[Biosynthesis of liver histones in rats at different periods of autogenesis].
Topics: Animals; Biological Evolution; Carbon Isotopes; Cysteine; Embryo, Mammalian; Female; Histones; Liver; Lysine; Maternal-Fetal Exchange; Methionine; Pregnancy; Rats; Sulfur Isotopes | 1968 |
Properties and enzymatic activities of papain insolubilized with glutaraldehyde.
Topics: Aldehydes; Amides; Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Cysteine; Esterases; Glutarates; Hydrogen-Ion Concentration; Kinetics; Lysine; Mercury; Papain; Peptide Hydrolases; Solubility; Sulfhydryl Compounds; Time Factors | 1969 |
Cationic amino acid transport in the rabbit reticulocyte. Na+-dependent inhibition of Na+-independent transport.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Biological Transport, Active; Bridged-Ring Compounds; Carbon Isotopes; Cysteine; Hydrogen-Ion Concentration; Hydroxybutyrates; In Vitro Techniques; Kinetics; Leucine; Lysine; Male; Ornithine; Rabbits; Reticulocytes; Sodium | 1969 |
Structural studies on rabbit muscle glycerol 3-phosphate dehydrogenase and a comparison of chemical and physical determinations of its molecular weight.
Topics: Alkylation; Amino Acids; Animals; Arginine; Autoradiography; Bees; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Chymotrypsin; Cysteine; Glycerolphosphate Dehydrogenase; Histidine; Isomerases; Kinetics; Lysine; Molecular Weight; Muscles; Rabbits; Rats; Species Specificity; Trypsin; Tryptophan; Tyrosine; Ultracentrifugation | 1969 |
Bacterial N-acetylation of an L-lysine antagonist, S-(beta-aminoethyl)-L-cysteine.
Topics: Carboxy-Lyases; Chromatography, Ion Exchange; Chromatography, Paper; Colorimetry; Cysteine; Electrophoresis; Enterobacter; Infrared Rays; Light; Lysine; Magnetic Resonance Spectroscopy; Rotation; Spectrum Analysis; X-Ray Diffraction | 1969 |
[Effect of antibiotics on incorporation of labelled amino acids in proteins of tissue culture cells].
Topics: Amino Acids; Animals; Antibiotics, Antineoplastic; Carbon Isotopes; Chick Embryo; Culture Techniques; Cysteine; Depression, Chemical; Fibroblasts; Glycine; Leucine; Lysine; Methionine; Neomycin; Oleandomycin; Penicillin G; Protein Biosynthesis; Stimulation, Chemical; Streptomycin; Tetracycline | 1969 |
Determination of dinitrophenylamino acids in structural proteins by chromatography on nylon powder columns. I. The water-soluble dinitrophenylamino acids.
Topics: Amino Acids; Animals; Chromatography; Collagen; Cysteine; Dinitrophenols; Hair; Hydrogen-Ion Concentration; Lysine; Methods; Nylons; Proteins; Serine; Textiles; Tyrosine; Wool | 1969 |
The reaction of iodoacetamide with the active center of gamma-glutamyl transpeptidase.
Topics: Alkylation; Amides; Animals; Autoradiography; Borates; Catalysis; Cattle; Cysteine; Electrophoresis; Enzymes; Glycolates; Histidine; In Vitro Techniques; Kidney; Lysine; Methionine; Molecular Weight; Serine; Transferases | 1965 |
S-N transfer and dual acetylation in the S-acetylation and N-acetylation of 3-phosphoglyceraldehyde dehydrogenase by substrates.
Topics: Acetates; Autoradiography; Carbon Isotopes; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; Lysine; Phosphates | 1966 |
Effects of dietary modifications on reponse of the duckling to aflatoxin.
Topics: Aflatoxins; Animal Feed; Animals; Arginine; Biological Assay; Cysteine; Diet; Fluorescence; Food; Glutathione; Growth; Hot Temperature; Liver; Lysine; Male; Methionine; Poultry; Poultry Diseases | 1966 |
Poly vinyl(N-phenylenemaleimide). A new selective binding agent for thiols.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Cysteine; Cytosine Nucleotides; Guanine Nucleotides; Imides; In Vitro Techniques; Indicators and Reagents; Lysine; Mercaptoethanol; Polystyrenes; Polyvinyls; RNA, Transfer; Salicylates; Uracil Nucleotides | 1966 |
Synthesis of some dibasic sulphur-containing amino-acids related to L-lysine.
Topics: Chemical Phenomena; Chemistry; Cysteine; Homocysteine; Lysine | 1966 |
A common renal transport system for lysine, ornithine, arginine and cysteine.
Topics: Animals; Arginine; Biological Transport; Cysteine; In Vitro Techniques; Kidney; Lysine; Ornithine; Radioisotopes; Radiometry; Rats | 1966 |
Dithiothreitol in the study of cysteine transport.
Topics: Alcohols; Animals; Arginine; Biological Transport; Cysteine; Cystine; Cystinuria; Humans; In Vitro Techniques; Kidney; Lysine; Ornithine; Rats; Sulfhydryl Compounds | 1966 |
[Two dimension chromatography of ether soluble dinitrophenyl-amino acids and chromato-electrophoresis of hydracid-soluble DNP-amino acids on thin layers of powdered cellulose].
Topics: Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography, Thin Layer; Cysteine; Dinitrophenols; Electrophoresis; Glutamates; Glutamine; Histidine; Lysine | 1966 |
Genetic control of the uptake of amino acids in Neurospora.
Topics: Amino Acids; Arginine; Cysteine; Enzyme Repression; Enzymes; Genes; Histidine; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Tryptophan; Tyrosine; Valine | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
[Composition and properties of the preparations isolated from Act. coelicolor with the aid of beta-naphtol].
Topics: Acetates; Actinomyces; Alanine; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glucosamine; Glutamates; Glycerol; Leucine; Lysine; Naphthalenes; Peptides; Phosphates; Ribose; Serine; Valine | 1966 |
Intestinal transport of cystine and cysteine in man: evidence for separate mechanisms.
Topics: Arginine; Biological Transport; Cysteine; Cystine; Cystinuria; Humans; Intestinal Mucosa; Jejunum; Lysine; Radioisotopes; Statistics as Topic | 1967 |
Exchange diffusion of dibasic amino acids in rat-kidney cortex slices.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Carbon Isotopes; Cell Membrane Permeability; Cysteine; Cystine; Kidney; Lysine; Ornithine; Rats; Sulfur Isotopes | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Effect of amino acids on microbial production of citric acid by Aspergillus niger.
Topics: Amino Acids; Aspartic Acid; Aspergillus niger; Citrates; Citric Acid; Cysteine; Glutamates; Glutamic Acid; Lysine; Serine | 1982 |
Chemical modification of mouse interferons.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Epitopes; Interferon Type I; Lysine; Mice; Structure-Activity Relationship; Tryptophan | 1982 |
Lysine excretion by S-(2-aminoethyl)L-cysteine resistant mutants of Bacillus subtilis.
Topics: Bacillus subtilis; Cysteine; Drug Resistance, Microbial; Lysine; Mutation | 1983 |
Actin-actin and actin-deoxyribonuclease I contact sites in the actin sequence.
Topics: Actins; Binding Sites; Cysteine; Deoxyribonuclease I; Endodeoxyribonucleases; Lysine; Protein Conformation; Succinimides | 1984 |
Transport of basic amino acids and regulation of aspartate kinase activity in thialysine and L-canavanine resistant strains of Serratia marcescens.
Topics: Amino Acids; Arginine; Aspartate Kinase; Aspartic Acid; Biological Transport; Canavanine; Cysteine; Drug Resistance, Microbial; Escherichia coli; Lysine; Phosphotransferases; Serratia marcescens | 1980 |
Regulation of lysine- and lysine-plus-threonine-inhibitable aspartokinases in Bacillus brevis.
Topics: Aspartate Kinase; Bacillus; Cysteine; Enzyme Repression; Isoleucine; Lysine; Mutation; Phosphotransferases; Threonine | 1980 |
Pig liver phosphomevalonate kinase. 2. Participation of cysteinyl and lysyl groups in catalysis.
Topics: Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Kinetics; Liver; Lysine; Mevalonic Acid; Phosphotransferases; Phosphotransferases (Phosphate Group Acceptor); Pyridoxal Phosphate; Swine | 1980 |
Thialysine and selenalysine as allosteric inhibitors of E. coli aspartokinase III.
Topics: Aspartate Kinase; Cysteine; Escherichia coli; Hot Temperature; Kinetics; Lysine; Organoselenium Compounds; Phosphotransferases; Selenium | 1982 |
beta-lactam antibiotic production by Streptomyces clavuligerus mutants impaired in regulation of aspartokinase.
Topics: Anti-Bacterial Agents; Aspartate Kinase; beta-Lactams; Cysteine; Drug Resistance, Microbial; Lysine; Mutation; Phosphotransferases; Streptomyces; Threonine | 1983 |
Effect of 2-aminoethyl-L-cysteine on collagen accumulation in isolated hepatic granulomas.
Topics: Animals; Collagen; Cysteine; Dose-Response Relationship, Drug; Female; Granuloma; Hydroxylation; Hydroxyproline; Liver; Liver Diseases; Lysine; Mice; Proline; Schistosomiasis | 1983 |
Amino acid sequence of Acanthamoeba actin.
Topics: Actins; Amino Acid Sequence; Amoeba; Animals; Cysteine; Lysine; Methylhistidines | 1984 |
Transport systems for lysine, thialysine and selenalysine in E. coli KL16.
Topics: Biological Transport; Culture Media; Cysteine; Escherichia coli; Kinetics; Lysine; Organoselenium Compounds; Selenium | 1983 |
Thialysine utilization by a lysine-requiring Escherichia coli mutant.
Topics: Bacterial Proteins; Cysteine; Escherichia coli; Lysine; Mutation | 1984 |
[Electrophoretic and electrophoretic-chromatographic picture in diseases of defective renal transport of amino acids with particular reference to personal cases].
Topics: Adolescent; Child; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis; Female; Glycine; Humans; Kidney; Lysine; Male; Renal Aminoacidurias | 1983 |
[Prevention of cysteine calculosis by the continuous administration of alpha-mercaptopropionylglycine].
Topics: Adolescent; Amino Acids, Sulfur; Cysteine; Electrophoresis; Humans; Lysine; Male; Renal Aminoacidurias; Tiopronin; Urinary Calculi | 1983 |
Repression of lysine transport in E. coli KL16.
Topics: Biological Transport; Cysteine; Escherichia coli; Kinetics; Lysine; Organoselenium Compounds; Ornithine; Selenium | 1983 |
Modification of actin with 2-(N-methylanilino)naphthalene-6-sulfonyl chloride.
Topics: Actins; Anilino Naphthalenesulfonates; Animals; Cysteine; Deoxyribonucleases; Fluorescent Dyes; Lysine; Potassium Chloride; Protein Binding; Rabbits; Spectrometry, Fluorescence; Viscosity | 1984 |
Transport of L-cystine in isolated perfused proximal straight tubules.
Topics: Animals; Biological Transport; Cycloleucine; Cysteine; Female; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Lysine; Membranes; Perfusion; Rabbits | 1984 |
F-actin is intermolecularly crosslinked by N,N'-p-phenylenedimaleimide through lysine-191 and cysteine-374.
Topics: Actins; Amino Acid Sequence; Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; Lysine; Macromolecular Substances; Maleimides; Rabbits | 1984 |
Escherichia coli regulatory mutation affecting lysine transport and lysine decarboxylase.
Topics: Amino Acids; Biological Transport, Active; Carboxy-Lyases; Cell-Free System; Chromosome Mapping; Cysteine; Drug Resistance, Microbial; Escherichia coli; Lysine; Mutation; Recombination, Genetic | 1980 |
Studies on the utilization of lysinoalanine and lanthionine.
Topics: Alanine; Amino Acids; Animals; Chickens; Cysteine; Dietary Proteins; Female; Hydrogen-Ion Concentration; Kidney; Lysine; Lysinoalanine; Male; Nutritive Value; Rats; Species Specificity; Structure-Activity Relationship; Sulfides | 1980 |
Amino acid sequence of a peptide containing an essential cysteine residue of yeast saccharopine dehydrogenase (L-lysine-forming).
Topics: Amino Acid Sequence; Cysteine; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Peptide Fragments; Saccharomyces cerevisiae; Saccharopine Dehydrogenases | 1980 |
Red blood cells amino-acid pattern in protein energy malnutrition and the effect of oral dosing with single amino acids.
Topics: Amino Acids; Amino Acids, Essential; Biological Transport; Child, Preschool; Cysteine; Erythrocytes; Humans; Infant; Kwashiorkor; Lysine; Protein-Energy Malnutrition; Tryptophan | 1980 |
Localization of a cross-link donor site in the alpha-chain of human fibrin.
Topics: Alanine; Amino Acid Sequence; Cross-Linking Reagents; Cyanogen Bromide; Cysteine; Fibrin; Fibrinogen; Lysine; Peptides; Threonine; Valine | 1980 |
Modification of mouse testicular lactate dehydrogenase by pyridoxal 5'-phosphate.
Topics: Animals; Binding Sites; Coenzymes; Cysteine; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lysine; Male; Mice; Nucleotides; Pyridoxal Phosphate; Testis | 1980 |
Bioavailability of some lysine derivatives in mice.
Topics: Animals; Biological Assay; Biological Availability; Body Weight; Cysteine; Dietary Proteins; Lysine; Mice; Structure-Activity Relationship | 1981 |
Primary structure of porcine heart citrate synthase.
Topics: Amino Acid Sequence; Animals; Citrate (si)-Synthase; Cysteine; Lysine; Molecular Weight; Myocardium; Oxo-Acid-Lyases; Peptide Fragments; Swine | 1981 |
[Studies on the enzymatical release of lysine, methionine, cyst(e)ine and tryptophan from casein and cereal proteins and their direct photometric determination].
Topics: Amino Acids; Caseins; Cysteine; Gliadin; Lysine; Methionine; Peptide Hydrolases; Photometry; Plant Proteins; Tryptophan | 1981 |
Genetic and biochemical properties of thialysine-resistant mutants of Saccharomyces cerevisiae.
Topics: Cysteine; Drug Resistance, Microbial; Genes, Dominant; Genes, Recessive; Lysine; Lysine-tRNA Ligase; Mutation; Saccharomyces cerevisiae; Temperature | 1981 |
Specific cleavage of glucosephosphate isomerases at cysteinyl residues using 2-nitro-5-thiocyanobenzoic acid: analyses of peptides eluted from polyacrylamide gels and localization of active site histidyl and lysyl residues.
Topics: Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Female; Glucose-6-Phosphate Isomerase; Histidine; Humans; Lysine; Muscles; Peptide Fragments; Placenta; Pregnancy; Sulfhydryl Reagents; Swine; Thiocyanates | 1981 |
Inhibition of proinsulin to insulin conversion in rat islets using arginine and lysine analogs. Lack of effect on rate of release of modified products.
Topics: Animals; Arginine; Canavanine; Cysteine; In Vitro Techniques; Insulin; Islets of Langerhans; Kinetics; Leucine; Lysine; Proinsulin; Rats; Tritium | 1982 |
The C-terminal peptide produced upon proteolytic activation of the cytolytic toxin aerolysin is not involved in channel formation.
Topics: Aeromonas hydrophila; Amino Acid Sequence; Bacterial Toxins; Binding Sites; Circular Dichroism; Cysteine; Endopeptidases; Fluorescent Dyes; Ion Channels; Isoleucine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Pore Forming Cytotoxic Proteins; Protein Conformation; Protein Precursors; Protein Structure, Secondary; Recombinant Proteins; Spectrometry, Fluorescence; Tryptophan | 1994 |
Investigation of the nature of o-phthalaldehyde reaction with octopine dehydrogenase.
Topics: 4-Chloromercuribenzenesulfonate; Amino Acid Oxidoreductases; Arginine; Binding Sites; Cysteine; Dithiothreitol; Enzyme Activation; Kinetics; Lysine; Mercaptoethanol; NAD; o-Phthalaldehyde; Protein Conformation; Pyruvates; Spectrometry, Fluorescence; Spectrophotometry; Substrate Specificity; Valine | 1994 |
Use of resonance energy transfer to determine the proximity of the guanine nucleotide binding site of transducin relative to a conformationally-sensitive site on the gamma subunit of the cyclic GMP phosphodiesterase.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Amino Acid Sequence; Anilino Naphthalenesulfonates; Animals; Binding Sites; Cattle; Cysteine; Energy Transfer; Eosine Yellowish-(YS); Fluorescent Dyes; Guanine Nucleotides; Lysine; Molecular Sequence Data; Sulfhydryl Reagents; Transducin | 1995 |
Examining the structural and chemical flexibility of the active site base, Lys-258, of Escherichia coli aspartate aminotransferase by replacement with unnatural amino acids.
Topics: Aspartate Aminotransferases; Binding Sites; Cysteine; Escherichia coli; Imines; Lysine; Models, Chemical; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Pyridoxamine; Spectrophotometry; Structure-Activity Relationship; Titrimetry | 1995 |
The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element.
Topics: Amino Acid Sequence; Binding Sites; Cells, Cultured; Cysteine; Disulfides; Extracellular Matrix; Glycine; Humans; Kinetics; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Receptors, Glycine; Serine; Strychnine; Taurine; Threonine; Tyrosine | 1995 |
Chemical modification of alpha(1-3) fucosyltransferase defines residues of catalytic importance.
Topics: Animals; Arginine; Binding Sites; Carbohydrate Sequence; Cell Line; Cloning, Molecular; Cysteine; Enzyme Inhibitors; Ethylmaleimide; Fucosyltransferases; Histidine; Humans; Kinetics; Lysine; Molecular Sequence Data; Recombinant Proteins; Spodoptera; Transfection; Tryptophan | 1995 |
The effects of amino acid-reactive reagents on the functioning of the inositol 1,4,5-trisphosphate-sensitive calcium channel from rat cerebellum.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Arginine; Binding Sites; Biological Transport, Active; Calcimycin; Calcium; Calcium Channels; Cerebellum; Cysteine; Inositol 1,4,5-Trisphosphate; Lysine; Microsomes; Phenylglyoxal; Rats; Ruthenium Red; Signal Transduction; Silver Nitrate; Vanadates | 1993 |
Decreasing the basicity of the active site base, Lys-258, of Escherichia coli aspartate aminotransferase by replacement with gamma-thialysine.
Topics: Amino Acid Sequence; Aspartate Aminotransferases; Binding Sites; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Mathematics; Mutagenesis, Site-Directed; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship; Thermodynamics | 1995 |
Use of site-directed mutagenesis and alternative substrates to assign the prototropic groups important to catalysis by Escherichia coli aspartate aminotransferase.
Topics: Aspartate Aminotransferases; Calorimetry; Catalysis; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Mathematics; Mutagenesis, Site-Directed; Osmolar Concentration; Recombinant Proteins; Substrate Specificity; Taurine | 1995 |
A formal method of determining the dietary amino acid requirements of laying-type pullets during their growing period.
Topics: Amino Acids; Animal Husbandry; Animals; Body Composition; Body Weight; Chickens; Cysteine; Diet; Feathers; Lipids; Lysine; Methionine; Nutritional Requirements; Proteins | 1994 |
Identification of essential lysyl and cysteinyl residues, and the amino acid sequence at the substrate-binding site of retinal oxidase.
Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Borohydrides; Chloromercuribenzoates; Cyanogen Bromide; Cysteine; Cytosol; Liver; Lysine; Male; Molecular Sequence Data; p-Chloromercuribenzoic Acid; Pyridoxal Phosphate; Rabbits; Retinal Dehydrogenase; Sequence Analysis; Trypsin | 1995 |
Molecular modelling of the human formyl peptide receptor.
Topics: Amino Acid Sequence; Binding Sites; Computer Simulation; Cysteine; Humans; Lysine; Models, Molecular; N-Formylmethionine Leucyl-Phenylalanine; Protein Structure, Secondary; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Spin-labeling study of the oxidative damage to low-density lipoprotein.
Topics: Apolipoproteins B; Binding Sites; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Microwaves; Molecular Structure; Oxidation-Reduction; Spin Labels | 1995 |
Interaction of alpha-crystallin with spin-labeled peptides.
Topics: Crystallins; Cysteine; Electron Spin Resonance Spectroscopy; Insulin; Light; Lysine; Melitten; Peptides; Protein Binding; Protein Folding; Scattering, Radiation; Spin Labels | 1995 |
Site-directed mutagenesis of human glutathione transferase P1-1. Spectral, kinetic, and structural properties of Cys-47 and Lys-54 mutants.
Topics: Base Sequence; Cysteine; Enzyme Stability; Glutathione Transferase; Humans; Hydrolysis; Isoenzymes; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Conformation; Spectrophotometry, Ultraviolet | 1995 |
Identification of two functionally distinct lysine-binding sites in kringle 37 and in kringles 32-36 of human apolipoprotein(a).
Topics: Amino Acid Sequence; Apolipoproteins; Apoprotein(a); Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Chromatography, Affinity; Cysteine; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Humans; Immunoblotting; Kringles; Lipoprotein(a); Liver Neoplasms; Lysine; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Plasmids; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Serine; Transfection; Tryptophan; Tumor Cells, Cultured | 1995 |
Site-directed mutagenesis of a reactive lysyl residue (Lys-247) of Rubisco activase.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Arginine; Cysteine; Electrophoresis, Polyacrylamide Gel; Glutamine; Isoelectric Focusing; Lysine; Mutagenesis, Site-Directed; Nicotiana; Photochemistry; Plant Proteins; Plants, Toxic; Point Mutation; Recombinant Proteins; Ribulose-Bisphosphate Carboxylase; Structure-Activity Relationship | 1994 |
The cooperative binding of chromosomal protein HMG-14 to nucleosome cores is reduced by single point mutations in the nucleosomal binding domain.
Topics: Alanine; Base Sequence; Binding Sites; Cysteine; Escherichia coli; Gene Expression; Glutamic Acid; High Mobility Group Proteins; Humans; Iodoacetamide; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleosomes; Point Mutation; Protein Conformation; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Compounds | 1994 |
Absorption of lysine and methionine from the proximal colon of the piglet.
Topics: Animal Feed; Animals; Colon; Cysteine; Diet; Intestinal Absorption; Lysine; Male; Methionine; Nitrogen; Swine; Urea | 1994 |
Different susceptibility to phospholipase A2 treatment of the fluorescence intensity changes in the vicinity of Cys-964 and Lys-501 in the alpha-chain of probe-labeled Na+,K(+)-ATPase.
Topics: Acrylamides; Animals; Binding Sites; Cysteine; Fluorescein-5-isothiocyanate; Fluorescence Polarization; Fluorescent Dyes; Hydrogen Bonding; Kidney; Lysine; Maleimides; Models, Molecular; Phospholipases A; Phospholipases A2; Polyethylene Glycols; Protein Conformation; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence; Swine | 1994 |
Rapid exchange of subunits of mammalian ornithine decarboxylase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, Affinity; Cysteine; Histidine; Kinetics; Lysine; Macromolecular Substances; Mice; Mutagenesis, Site-Directed; Ornithine Decarboxylase; Plasmids; Point Mutation; Protein Biosynthesis; Restriction Mapping; Transcription, Genetic | 1994 |
Copper-amino acid complexes are partially protected against inhibitory effects of L-cysteine and L-ascorbic acid on copper absorption in chicks.
Topics: Animals; Ascorbic Acid; Bile; Biological Availability; Chickens; Copper; Cysteine; Diet; Liver; Lysine; Methionine; Molecular Structure; Random Allocation | 1994 |
Reactivity of cysteinyl, arginyl, and lysyl residues of Escherichia coli phosphoenolpyruvate carboxykinase against group-specific chemical reagents.
Topics: Arginine; Binding Sites; Cysteine; Diacetyl; Escherichia coli; Glyoxal; Kinetics; Lysine; Phosphoenolpyruvate Carboxykinase (GTP); Pyrenes; Pyridoxal Phosphate; Sulfhydryl Reagents | 1993 |
Replacement of active-site lysine-239 of thermostable aspartate aminotransferase by S-(2-aminoethyl)cysteine: properties of the mutant enzyme.
Topics: Aspartate Aminotransferases; Binding Sites; Cysteine; Enzyme Stability; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Pyridoxal Phosphate; Temperature; Thermodynamics | 1994 |
Studies of the active-site lysyl residue of thermostable aspartate aminotransferase: combination of site-directed mutagenesis and chemical modification.
Topics: Aspartate Aminotransferases; Bacillus; Binding Sites; Circular Dichroism; Cysteine; Enzyme Stability; Lysine; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Structure-Activity Relationship; Temperature | 1994 |
Precursor flux control through targeted chromosomal insertion of the lysine epsilon-aminotransferase (lat) gene in cephamycin C biosynthesis.
Topics: Base Sequence; Blotting, Southern; Cephamycins; Chromosomes, Bacterial; Cysteine; DNA Primers; DNA, Bacterial; Genes, Bacterial; Kinetics; L-Lysine 6-Transaminase; Lysine; Models, Biological; Molecular Sequence Data; Mutagenesis, Insertional; Plasmids; Recombination, Genetic; Restriction Mapping; RNA, Messenger; Streptomyces; Transaminases; Transcription, Genetic; Valine | 1993 |
Biochemical analysis of Escherichia coli selenophosphate synthetase mutants. Lysine 20 is essential for catalytic activity and cysteine 17/19 for 8-azido-ATP derivatization.
Topics: Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Azides; Bacterial Proteins; Base Sequence; Catalysis; Cysteine; Drosophila Proteins; Escherichia coli; Lysine; Metals; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphotransferases; Substrate Specificity | 1993 |
Evidence for proximal cysteine and lysine residues present at the nucleotide domain of rabbit muscle creatine kinase.
Topics: Animals; Creatine Kinase; Cysteine; Lysine; Muscles; o-Phthalaldehyde; Rabbits; Spectrometry, Fluorescence; Substrate Specificity | 1993 |
Differential roles for Fos and Jun in DNA-binding: redox-dependent and independent functions.
Topics: Animals; Arginine; Cysteine; DNA; Humans; Lysine; Mutagenesis; Oxidation-Reduction; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats | 1993 |
Acrylodan can label amino as well as sulfhydryl groups: results with low-density lipoprotein, lipoprotein[a], and lipid-free proteins.
Topics: 2-Naphthylamine; Artifacts; Cysteine; Fluorescent Dyes; Humans; Kinetics; Lipoprotein(a); Lipoproteins; Lipoproteins, LDL; Lysine; Molecular Probes; Serum Albumin, Bovine | 1993 |
A single point mutation in the VP7 major core protein of bluetongue virus prevents the formation of core-like particles.
Topics: Antigens, Viral; Base Sequence; Bluetongue virus; Capsid; Capsid Proteins; Cysteine; DNA Mutational Analysis; Lysine; Molecular Sequence Data; Morphogenesis; Mutagenesis, Site-Directed; Point Mutation; Structure-Activity Relationship; Viral Core Proteins | 1993 |
Involvement of different cysteines in the inactivation of octopine dehydrogenase by p-chloromercuricphenyl sulfonic acid and o-phthalaldehyde.
Topics: 4-Chloromercuribenzenesulfonate; Amino Acid Oxidoreductases; Binding Sites; Cysteine; Dithiothreitol; Indoles; Lysine; NAD; o-Phthalaldehyde; Spectrometry, Fluorescence | 1993 |
Role of the charge pair aspartic acid-237-lysine-358 in the lactose permease of Escherichia coli.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Biological Transport, Active; Cysteine; Electrochemistry; Enzyme Stability; Escherichia coli; Escherichia coli Proteins; Kinetics; Lactose; Lysine; Membrane Transport Modulators; Membrane Transport Proteins; Methylation; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Structure-Activity Relationship; Sulfhydryl Reagents; Symporters | 1993 |
Kinetics of structural changes of reconstituted skeletal muscle thin filaments observed by fluorescence resonance energy transfer.
Topics: Actins; Animals; Calcium; Cysteine; Energy Transfer; Fluorescence; Fluorescence Polarization; Kinetics; Lysine; Muscles; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Tropomyosin; Troponin | 1993 |
Intersubunit location of the active site of mammalian ornithine decarboxylase as determined by hybridization of site-directed mutants.
Topics: Alanine; Animals; Base Sequence; Binding Sites; Cysteine; Eflornithine; Lysine; Macromolecular Substances; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Ornithine Decarboxylase; Pyridoxal Phosphate; Structure-Activity Relationship | 1993 |
Chemical modifications of chicken liver pyruvate carboxylase: evidence for essential cysteine-lysine pairs and a reactive sulfhydryl group.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Carbamyl Phosphate; Chickens; Cysteine; Ethylmaleimide; Hydrogen-Ion Concentration; Liver; Lysine; Maleimides; o-Phthalaldehyde; Oxaloacetates; Phosphorylation; Pyruvate Carboxylase; Structure-Activity Relationship; Sulfhydryl Compounds | 1993 |
A dinucleotide mutation in dihydrodipicolinate synthase of Nicotiana sylvestris leads to lysine overproduction.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Southern; Cysteine; DNA Probes; DNA, Complementary; Drug Resistance; Escherichia coli; Genetic Complementation Test; Genomic Library; Hydro-Lyases; Lysine; Molecular Sequence Data; Mutation; Nicotiana; Plants, Toxic; Selection, Genetic; Sequence Analysis; Sequence Homology, Amino Acid | 1995 |
Inactivation of an NADPH-dependent succinic semialdehyde reductase by o-phthalaldehyde.
Topics: Animals; Binding Sites; Brain; Cattle; Cross-Linking Reagents; Cysteine; Enzyme Inhibitors; Hydroxybutyrate Dehydrogenase; Indoles; Kinetics; Lysine; NADP; o-Phthalaldehyde | 1996 |
Blocking the Ca2+-induced conformational transitions in calmodulin with disulfide bonds.
Topics: Binding Sites; Calcineurin; Calcium; Calmodulin; Calmodulin-Binding Proteins; Cloning, Molecular; Cysteine; Disulfides; Enzyme Activation; Glutamine; Helix-Loop-Helix Motifs; Humans; Isoleucine; Kinetics; Leucine; Liver; Lysine; Models, Molecular; Models, Structural; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphoric Diester Hydrolases; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Troponin; Troponin C | 1996 |
Alteration in the conformational stability of collagen caused by the incorporation of the lysine analogue S-2-aminoethylcysteine.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Chick Embryo; Chromatography, Agarose; Collagen; Cysteine; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Hydroxylation; Kinetics; Lysine; Molecular Structure; Pepsin A; Proline; Protein Conformation; Protein Synthesis Inhibitors; RNA, Transfer, Lys; Transfer RNA Aminoacylation; Tyrosine | 1996 |
Identification of cysteine and lysine residues present at the active site of beef liver glutamate dehydrogenase by o-phthalaldehyde.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Binding Sites; Cattle; Cysteine; Enzyme Inhibitors; Glutamate Dehydrogenase; Indoles; Ketoglutaric Acids; Kinetics; Liver; Lysine; Mercaptoethanol; Models, Chemical; NAD; o-Phthalaldehyde; Spectrometry, Fluorescence | 1996 |
Effects of the type of divalent cation, Ca2+ or Mg2+, bound at the high-affinity site and of the ionic composition of the solution on the structure of F-actin.
Topics: Actins; Amino Acid Sequence; Animals; Binding Sites; Calcium; Cations, Divalent; Cysteine; Fluorescent Dyes; Lysine; Macromolecular Substances; Magnesium; Molecular Sequence Data; Muscle, Skeletal; Naphthalenesulfonates; Peptide Fragments; Peptide Mapping; Protein Conformation; Rabbits; Solutions; Subtilisins; Trypsin | 1996 |
Labelling the Ca(2+)-ATPase of skeletal-muscle sarcoplasmic reticulum with the cross-linker o-phthalaldehyde.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Cross-Linking Reagents; Cysteine; Enzyme Inhibitors; Fluorescence; Indoles; Lysine; Magnesium; Methylamines; o-Phthalaldehyde; Rabbits; Sarcoplasmic Reticulum | 1996 |
Distance measurements near the myosin head-rod junction using fluorescence spectroscopy.
Topics: Allosteric Site; Anilino Naphthalenesulfonates; Animals; Binding Sites; Biophysical Phenomena; Biophysics; Chickens; Cysteine; Energy Transfer; Fluorescent Dyes; In Vitro Techniques; Lysine; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Myosin Subfragments; Rabbits; Spectrometry, Fluorescence; Swine; Thermodynamics | 1996 |
The C-terminal part of diacylglycerol kinase alpha lacking zinc fingers serves as a catalytic domain.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Chlorocebus aethiops; Conserved Sequence; COS Cells; Cysteine; Diacylglycerol Kinase; Diglycerides; DNA Primers; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Recombinant Proteins; Sequence Deletion; Transfection; Zinc Fingers | 1996 |
Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Chromatography, Ion Exchange; Cloning, Molecular; Conserved Sequence; Cysteine; DNA Helicases; DNA Probes; Escherichia coli; Fungal Proteins; Glutamic Acid; Histidine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; RNA Helicases; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators | 1996 |
Reactivity of essential cysteine and lysine residues present at the catalytic domain of pig heart mitochondrial malate dehydrogenase.
Topics: Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Lysine; Malate Dehydrogenase; Mitochondria, Heart; NAD; o-Phthalaldehyde; Pyridoxal Phosphate; Swine | 1995 |
Effects of buried charged groups on cysteine thiol ionization and reactivity in Escherichia coli thioredoxin: structural and functional characterization of mutants of Asp 26 and Lys 57.
Topics: Amino Acid Sequence; Aspartic Acid; Bacteriophage T7; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oxidation-Reduction; Solubility; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfhydryl Compounds; Thioredoxin-Disulfide Reductase; Thioredoxins; Titrimetry; Tryptophan; Viral Proteins | 1997 |
Carbonyl reducing 17 beta-hydroxysteroid dehydrogenase from the filamentous fungus Cochliobolus lunatus.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Androstenedione; Ascomycota; Binding Sites; Binding, Competitive; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Hydroxysteroid Dehydrogenases; Immunoblotting; Kinetics; Lysine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Tetranitromethane; Trinitrobenzenesulfonic Acid; Tyrosine; Vitamin K | 1997 |
Structural and functional aspects of rat microsomal glutathione transferase. The roles of cysteine 49, arginine 107, lysine 67, histidine, and tyrosine residues.
Topics: Amino Acid Sequence; Animals; Arginine; Cysteine; Enzyme Inhibitors; Glutathione Transferase; Histidine; Indicators and Reagents; Lysine; Male; Microsomes, Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylglyoxal; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid; Tyrosine | 1997 |
Substitutions of alanine for cysteine at a reactive thiol site and for lysine at a pyridoxal phosphate binding site of 1-aminocyclopropane-1-carboxylate deaminase.
Topics: Absorption; Alanine; Base Sequence; Binding Sites; Carbon-Carbon Lyases; Catalysis; Cysteine; Escherichia coli; Gene Expression Regulation, Enzymologic; Lyases; Lysine; Mutagenesis, Site-Directed; Mutation; Plasmids; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Substrate Specificity; Sulfhydryl Compounds; Valine | 1997 |
Modification of brain glutamate dehydrogenase isoproteins with pyridoxal 5'-phosphate.
Topics: Animals; Borohydrides; Brain; Cattle; Cysteine; Enzyme Inhibitors; Enzyme Reactivators; Glutamate Dehydrogenase; Isoenzymes; Lysine; Pyridoxal Phosphate | 1996 |
Chemical modification of proteins for sequence analysis.
Topics: Acrylamide; Acrylamides; Alkylation; Amino Acids; Cysteine; Formates; Iodoacetates; Iodoacetic Acid; Lysine; Oxidation-Reduction; Phenylthiohydantoin; Proteins; Pyridines; Sequence Analysis; Succinic Anhydrides | 1997 |
Identification of a pore lining segment in gap junction hemichannels.
Topics: Amino Acid Sequence; Animals; Connexins; Cysteine; Gap Junctions; Lysine; Maleimides; Mutagenesis; Oocytes; Porins; Protein Conformation; Sequence Homology, Amino Acid; Xenopus | 1997 |
Mechanisms of sodium/calcium selectivity in sodium channels probed by cysteine mutagenesis and sulfhydryl modification.
Topics: Amino Acid Sequence; Animals; Calcium; Conserved Sequence; Cysteine; Lysine; Membrane Potentials; Models, Molecular; Models, Structural; Muscle, Skeletal; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Point Mutation; Protein Structure, Secondary; Rats; Recombinant Proteins; Sodium; Sodium Channels; Substrate Specificity | 1997 |
Mapping the mechanism-based modification sites in L-aspartase from Escherichia coli.
Topics: Aspartate Ammonia-Lyase; Aspartic Acid; Bacterial Proteins; Chromatography, High Pressure Liquid; Cysteine; Deamination; Enzyme Inhibitors; Escherichia coli; Fumarates; Lysine; Mutagenesis, Site-Directed; Peptide Fragments | 1997 |
Inactivation of yeast glutathione reductase by O-phthalaldehyde.
Topics: Cysteine; Enzyme Activation; Ethylmaleimide; Glutathione Reductase; Lysine; o-Phthalaldehyde; Spectrometry, Fluorescence; Substrate Specificity; Sulfhydryl Reagents; Yeasts | 1996 |
The helicase domain of phage P4 alpha protein overlaps the specific DNA binding domain.
Topics: Adenosine Triphosphatases; Binding Sites; Cysteine; DNA Helicases; DNA Primase; DNA-Binding Proteins; Glycine; Histidine; Lysine; Mutation; Recombinant Fusion Proteins; RNA Nucleotidyltransferases; Substrate Specificity; Thioredoxins; Viral Proteins | 1997 |
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays | 1997 |
C-terminal sequence determination of modified peptides by MALDI MS.
Topics: Amino Acid Sequence; Carboxypeptidases; Cathepsin A; Cysteine; Glutamine; Lysine; Molecular Sequence Data; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Vasoactive Intestinal Peptide | 1997 |
Improvement of lysine production by analog-sensitive and auxotroph mutants of the acetylene-utilizing bacterium Gordona bronchialis (Rhodococcus bronchialis).
Topics: Acetylene; Asparagine; Cysteine; Drug Resistance, Microbial; Lysine; Mutation; Pyruvates; Rhodococcus | 1997 |
Identification of equivalent residues in the gamma, delta, and epsilon subunits of the nicotinic receptor that contribute to alpha-bungarotoxin binding.
Topics: Animals; Bungarotoxins; Cell Line; Cysteine; Humans; Lysine; Mice; Mutagenesis, Site-Directed; Protein Binding; Receptors, Nicotinic; Recombinant Proteins | 1997 |
Evaluation of protein and energy quality of rendered spent hen meals.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cysteine; Diet; Dietary Proteins; Digestion; Energy Intake; Lysine; Male; Methionine; Nutritive Value | 1997 |
Site and significance of cysteine residues in xylose reductase from Neurospora crassa as deduced by fluorescence studies.
Topics: Aldehyde Reductase; Binding Sites; Binding, Competitive; Circular Dichroism; Cysteine; Enzyme Activation; Hydroxymercuribenzoates; Kinetics; Lysine; Neurospora crassa; o-Phthalaldehyde; Protein Conformation; Spectrometry, Fluorescence; Substrate Specificity | 1997 |
The conversion from the dehydrogenase type to the oxidase type of rat liver xanthine dehydrogenase by modification of cysteine residues with fluorodinitrobenzene.
Topics: Amino Acid Sequence; Animals; Cattle; Chickens; Chromatography, High Pressure Liquid; Cysteine; Dinitrofluorobenzene; Liver; Lysine; Molecular Sequence Data; Rats; Spectrophotometry, Atomic; Xanthine Dehydrogenase; Xanthine Oxidase | 1997 |
Dimerization of the synaptic vesicle protein synaptobrevin (vesicle-associated membrane protein) II depends on specific residues within the transmembrane segment.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Cross-Linking Reagents; Cysteine; Dimerization; Escherichia coli; Lysine; Macromolecular Substances; Membrane Proteins; Models, Structural; Molecular Sequence Data; Oxidation-Reduction; Protein Structure, Secondary; R-SNARE Proteins; Rats; Recombinant Fusion Proteins; Synaptic Vesicles | 1997 |
Site-specific incorporation of biotinylated amino acids to identify surface-exposed residues in integral membrane proteins.
Topics: Amino Acids; Animals; Biotinylation; Cell Membrane; Cysteine; Glycosylation; Immunodominant Epitopes; Iodine Radioisotopes; Lysine; Membrane Proteins; Mice; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Receptors, Nicotinic; Tyrosine; Xenopus laevis | 1997 |
Lysine-overproducing mutants of Saccharomyces cerevisiae baker's yeast isolated in continuous culture.
Topics: Amino Acids; Cysteine; Dietary Supplements; DNA, Fungal; Drug Resistance, Microbial; Fermentation; Genes, Fungal; Hydrogen-Ion Concentration; Karyotyping; Lysine; Mutation; Oxo-Acid-Lyases; Ploidies; Protein Synthesis Inhibitors; Saccharomyces cerevisiae; Spores, Fungal | 1997 |
Effect of selective cysteine --> alanine replacements on the catalytic functions of lysine: N6-hydroxylase.
Topics: 2,6-Dichloroindophenol; Alanine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyanogen Bromide; Cysteine; Dithionitrobenzoic Acid; Flavoproteins; Iodoacetates; Iodoacetic Acid; Lysine; Mass Spectrometry; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Peptide Fragments; Protein Conformation; Recombinant Proteins; Sequence Analysis; Trypsin | 1997 |
Evidence for modulation of the interaction between Cys-47 and Lys-54 in glutathione S-transferase Pi by the nature of the residue at position 56.
Topics: Animals; Binding Sites; Cysteine; Ethacrynic Acid; Glutathione Transferase; Humans; Isoenzymes; Kinetics; Lysine; Mice | 1997 |
Elimination of the Cys558-Cys566 bond in Lys78-plasminogen--effect on activation and fibrin interaction.
Topics: Animals; Cricetinae; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibrin; Fibrinolysin; Lysine; Plasminogen; Recombinant Proteins; Serine; Serine Endopeptidases; Streptokinase; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 1998 |
Globulin and albumin proteins in dehulled seeds of three Phaseolus vulgaris cultivars.
Topics: Albumins; Amino Acids; Buffers; Cysteine; Electrophoresis, Polyacrylamide Gel; Fabaceae; Globulins; Lysine; Methionine; Molecular Weight; Plant Proteins; Plants, Medicinal; Seeds | 1997 |
Identification of histidine residues in the sugar binding site of snake gourd (Trichosanthes anguina) seed lectin.
Topics: Binding Sites; Cysteine; Galactose; Histidine; Imidazoles; Lectins; Lysine; Plant Lectins; Plant Proteins; Seeds; Tryptophan; Tyrosine | 1998 |
Visualization of proteins by modification of lysines, cysteines, and phosphorylated serines facilitates sample preparation for microsequencing.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis, Polyacrylamide Gel; Lysine; Mass Spectrometry; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Proteins; Sequence Analysis; Serine; Trypsin | 1998 |
Determination of external loop topology in the serotonin transporter by site-directed chemical labeling.
Topics: Biotin; Carrier Proteins; Cysteine; Lysine; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Conformation; Serotonin Plasma Membrane Transport Proteins; Succinimides | 1998 |
Structural replacement of active site monovalent cations by the epsilon-amino group of lysine in the ATPase fragment of bovine Hsc70.
Topics: Adenosine Triphosphatases; Amines; Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Binding Sites; Carrier Proteins; Cations, Monovalent; Cattle; Crystallography, X-Ray; Cysteine; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hydrolysis; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments | 1998 |
Effect of Ca2+-Mg2+ exchange on the flexibility and/or conformation of the small domain in monomeric actin.
Topics: Actins; Animals; Calcium; Calibration; Cysteine; Energy Transfer; Fluorescent Dyes; Lysine; Magnesium; Models, Molecular; Muscle, Skeletal; Naphthalenesulfonates; Protein Conformation; Rabbits; Spectrometry, Fluorescence | 1998 |
Involvement of products of the nrfEFG genes in the covalent attachment of haem c to a novel cysteine-lysine motif in the cytochrome c552 nitrite reductase from Escherichia coli.
Topics: Anaerobiosis; Chromatography, High Pressure Liquid; Cysteine; Cytochrome c Group; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Deletion; Genes, Bacterial; Heme; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Mutation; Nitrite Reductases; Operon; Oxidation-Reduction; Plasmids | 1998 |
Role of cysteine and lysine residues in human hypoxanthine-guanine phosphoribosyltransferase.
Topics: Amino Acid Substitution; Cloning, Molecular; Cysteine; Disulfides; Erythrocytes; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Lysine; Macromolecular Substances; Mass Spectrometry; Mutagenesis, Site-Directed; Point Mutation; Recombinant Proteins; Trinitrobenzenesulfonic Acid | 1998 |
Information from the water stripe in TOCSY experiments on systems with exchangeable protons.
Topics: Amino Acids; Carbon; Cysteine; Electron Spin Resonance Spectroscopy; Hydrogen; Hydroxyl Radical; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Nitrogen; Peptides; Protons; Solvents; Sucrose; Threonine; Time Factors; Tyrosine; Water | 1998 |
Light-directed activation of protein activity from caged protein conjugates.
Topics: Actins; Animals; Contractile Proteins; Cysteine; Cytoskeletal Proteins; Fluorescent Dyes; In Vitro Techniques; Indicators and Reagents; Kinetics; Lysine; Microfilament Proteins; Molecular Probes; Myosin Subfragments; Photochemistry; Profilins; Proteins; Recombinant Proteins; Rhodamines | 1998 |
Calculations of electrostatic interactions and pKas in the active site of Escherichia coli thioredoxin.
Topics: Aspartic Acid; Binding Sites; Crystallography, X-Ray; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Lysine; Mathematical Computing; Models, Chemical; Oxidation-Reduction; Protein Conformation; Static Electricity; Thermodynamics; Thioredoxins | 1998 |
Chemical modification of barley root oxalate oxidase shows the presence of a lysine, a carboxylate, and disulfides, essential for enzyme activity.
Topics: Arginine; Carboxylic Acids; Cysteine; Disulfides; Enzyme Activation; Histidine; Hordeum; Lysine; Metals; Oxidoreductases; Plant Roots; Protein Binding; Tyrosine | 1998 |
Conformational changes at the highly reactive cystein and lysine regions of skeletal muscle myosin induced by formation of transition state analogues.
Topics: Adenosine Triphosphatases; Anilino Naphthalenesulfonates; Animals; Chickens; Cysteine; Lysine; Muscle, Skeletal; Myosins; Picrates; Protein Conformation; Spectrometry, Fluorescence; Sulfhydryl Reagents | 1998 |
Cysteines 849 and 942 of human mineralocorticoid receptor are crucial for steroid binding.
Topics: Aldosterone; Animals; Binding Sites; Cell Line; Cysteine; Glycine; Haplorhini; Humans; Luciferases; Lysine; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Mutagenesis, Site-Directed; Peptide Fragments; Progesterone; Receptors, Mineralocorticoid; Transcriptional Activation | 1998 |
Backbone flexibility of five sites on the catalytic subunit of cAMP-dependent protein kinase in the open and closed conformations.
Topics: Animals; Binding Sites; Catalysis; Cyclic AMP-Dependent Protein Kinases; Cysteine; Fluoresceins; Fluorescence Polarization; Lysine; Mice; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Protein Conformation | 1998 |
Exploring a channel to the active site of copper/topaquinone-containing phenylethylamine oxidase by chemical modification and site-specific mutagenesis.
Topics: 4-Chloro-7-nitrobenzofurazan; Amine Oxidase (Copper-Containing); Amino Acid Sequence; Apoenzymes; Binding Sites; Copper; Cysteine; Dihydroxyphenylalanine; Dithionitrobenzoic Acid; Fluorescent Dyes; Histidine; Holoenzymes; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Substrate Specificity | 1998 |
[New approach to the study of interaction of amino acid side groups with aryl azides].
Topics: Amino Acids; Azides; Cystamine; Cysteine; Diamines; Electrophoresis, Polyacrylamide Gel; Histamine; Histidine; Imidazoles; Lysine; Models, Molecular; Oligonucleotides; Ultraviolet Rays | 1998 |
Selective plasminogen binding: cysteinyl-lysine-dextran protein interactions.
Topics: Animals; Blood Proteins; Cattle; Cysteine; Dextrans; Lysine; Plasminogen; Protein Binding; Surface Properties | 1998 |
Rate-determining step of Escherichia coli alkaline phosphatase altered by the removal of a positive charge at the active center.
Topics: Alanine; Alkaline Phosphatase; Binding Sites; Cysteine; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Phosphates | 1999 |
The cysteine-proximal aspartates in the Fx-binding niche of photosystem I. Effect of alanine and lysine replacements on photoautotrophic growth, electron transfer rates, single-turnover flash efficiency, and EPR spectral properties.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Cyanobacteria; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Kinetics; Lysine; Membrane Proteins; Mutagenesis, Site-Directed; NADP; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Structure-Activity Relationship | 1999 |
High-throughput mass spectrometric discovery of protein post-translational modifications.
Topics: Acetylation; Amides; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Escherichia coli; Image Processing, Computer-Assisted; Keratins; Lysine; Methionine; Methylation; Molecular Sequence Data; Oxidoreductases; Peptide Elongation Factor Tu; Peptide Mapping; Peroxidases; Peroxiredoxins; Phenylalanine; Protein Processing, Post-Translational; Software; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 1999 |
Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.
Topics: Animals; Asparagine; Binding, Competitive; Conserved Sequence; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Proline; Protein Binding; Proteins; Receptors, Cell Surface; RGS Proteins; Serine | 1999 |
Aminoethylcysteine can replace the function of the essential active site lysine of Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Cysteine; Enzyme Activation; Hydroxymethylglutaryl CoA Reductases; Iodoacetamide; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Pseudomonas | 1999 |
Structural information on a membrane transport protein from nuclear magnetic resonance spectroscopy using sequence-selective nitroxide labeling.
Topics: Amino Acid Sequence; Biological Transport; Carrier Proteins; Cell Membrane; Cyclic N-Oxides; Cysteine; Escherichia coli Proteins; Lysine; Maleimides; Membrane Transport Proteins; Monosaccharide Transport Proteins; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spin Labels; Streptococcus; Substrate Specificity; Symporters | 1999 |
The tert-butyl hydroperoxide-induced oxidation of actin Cys-374 is coupled with structural changes in distant regions of the protein.
Topics: Actins; Animals; Chymotrypsin; Cross-Linking Reagents; Cyanogen Bromide; Cysteine; Hydrolysis; Kinetics; Lysine; Oxidants; Peptide Fragments; Polymers; Protein Conformation; Protein Denaturation; Rabbits; Spectrometry, Fluorescence; Subtilisins; Sulfhydryl Compounds; tert-Butylhydroperoxide; Tryptophan; Urea | 1999 |
Rhodobacter sphaeroides phosphoribulokinase: identification of lysine-165 as a catalytic residue and evaluation of the contributions of invariant basic amino acids to ribulose 5-phosphate binding.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cysteine; Gluconates; Kinetics; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphotransferases (Alcohol Group Acceptor); Pyridoxal Phosphate; Rhodobacter sphaeroides; Ribulosephosphates | 1999 |
Importance of F1-ATPase residue alpha-Arg-376 for catalytic transition state stabilization.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Arginine; Binding Sites; Catalysis; Cysteine; Enzyme Stability; Escherichia coli; Fluorine; Glutamine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Proton-Translocating ATPases; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1999 |
The mycotoxin patulin induces intra- and intermolecular protein crosslinks in vitro involving cysteine, lysine, and histidine side chains, and alpha-amino groups.
Topics: Animals; Cattle; Chickens; Cross-Linking Reagents; Cysteine; Dansyl Compounds; Female; Fluorescent Dyes; Glutathione; Histidine; Lysine; Muramidase; Patulin; Protein Conformation; Protein Structure, Tertiary; Serum Albumin, Bovine; Sulfhydryl Compounds; Tubulin | 1999 |
Lysine 219 participates in NADPH specificity in a flavin-containing monooxygenase from Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cysteine; Escherichia coli; Flavin-Adenine Dinucleotide; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Oxygenases; Phosphates; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Alignment; Substrate Specificity | 1999 |
Cysteine scanning mutagenesis of the noncatalytic nucleotide binding site of the yeast V-ATPase.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Binding Sites; Cysteine; Lysine; Maleimides; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Proton-Translocating ATPases; Saccharomyces cerevisiae; Vacuolar Proton-Translocating ATPases; Vacuoles | 2000 |
Biomimetic synthesis of ordered silica structures mediated by block copolypeptides.
Topics: Cysteine; Hydrogen-Ion Concentration; Light; Lysine; Microscopy, Electron, Scanning; Oxidation-Reduction; Peptides; Scattering, Radiation; Silanes; Silicon Dioxide; Solubility; Temperature | 2000 |
Two novel mutations consisting in minor gene rearrangements in the human low density lipoprotein receptor gene in Italian patients affected by familial hypercholesterolemia. Mutations in brief no. 194. Online.
Topics: Amino Acid Substitution; Cysteine; Frameshift Mutation; Glutamic Acid; Humans; Hyperlipoproteinemia Type II; Italy; Lysine; Receptors, LDL | 1998 |
Disruption of interkringle disulfide bond of plasminogen kringle 1-3 changes the lysine binding capability of kringle 2, but not its antiangiogenic activity.
Topics: Amino Acid Substitution; Angiogenesis Inhibitors; Animals; Cattle; Cell Division; Chick Embryo; Chorion; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Humans; Kringles; Ligands; Lysine; Mutation; Neovascularization, Physiologic; Plasminogen; Protein Binding; Protein Folding; Recombinant Proteins; Thermodynamics | 2000 |
Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
Topics: Allylglycine; Bacterial Proteins; Binding Sites; Catalysis; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Dimerization; Histidine; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Lyases; Lysine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Structure, Secondary; Pyridoxal Phosphate; Selenomethionine; Spectrophotometry; Sulfur; Thermotoga maritima; Transaminases | 2000 |
Characterization of the N-oligosaccharides attached to the atypical Asn-X-Cys sequence of recombinant human epidermal growth factor receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Carbohydrate Sequence; CHO Cells; Cricetinae; Cysteine; ErbB Receptors; Glycosylation; Humans; Lysine; Molecular Sequence Data; Oligosaccharides; Recombinant Proteins; Transfection | 2000 |
Uphill electron transfer in the tetraheme cytochrome subunit of the Rhodopseudomonas viridis photosynthetic reaction center: evidence from site-directed mutagenesis.
Topics: Amino Acid Substitution; Cysteine; Cytochrome c Group; Electron Transport; Heme; Kinetics; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Plasmids; Rhodopseudomonas; Spectrophotometry | 2000 |
Do cysteine 230 and lysine 238 of biotin carboxylase play a role in the activation of biotin?
Topics: Animals; Binding Sites; Biotin; Carbon-Nitrogen Ligases; Catalysis; Cysteine; Lysine; Mutagenesis, Site-Directed; Substrate Specificity | 2000 |
C-terminal sequence analysis of peptides and proteins using carboxypeptidases and mass spectrometry after derivatization of Lys and Cys residues.
Topics: Amino Acid Sequence; Animals; Carboxypeptidases; Cathepsin A; Cysteine; Lysine; Molecular Sequence Data; Peptides; Secretin; Sequence Analysis, Protein; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Vasoactive Intestinal Peptide | 1997 |
Impaired secretion of rat mannose-binding protein resulting from mutations in the collagen-like domain.
Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Carrier Proteins; CHO Cells; Collagen; Collectins; Complement Fixation Tests; Cricetinae; Cysteine; Endoplasmic Reticulum; Glutamic Acid; Glycine; Humans; Lectins; Lysine; Mannans; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Rats; Time Factors; Transfection | 2000 |
Cysteine-lysine ion pairs in yeast pyruvate carboxylase.
Topics: Animals; Chickens; Cysteine; Kinetics; Liver; Lysine; Pyruvate Carboxylase; Saccharomyces cerevisiae | 1998 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Chemical cross-linking with thiol-cleavable reagents combined with differential mass spectrometric peptide mapping--a novel approach to assess intermolecular protein contacts.
Topics: Amino Acid Sequence; B7-1 Antigen; Bacterial Proteins; Binding Sites; CD28 Antigens; Cross-Linking Reagents; Cysteine; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Lysine; Molecular Sequence Data; Peptide Mapping; Repressor Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2000 |
Arg-425 of the citrate transporter CitP is responsible for high affinity binding of di- and tricarboxylates.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Carrier Proteins; Cysteine; Dicarboxylic Acids; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Hydroxybutyrates; Immunoblotting; Kinetics; Lysine; Malates; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Substrate Specificity; Sulfhydryl Reagents; Symporters; Time Factors; Tricarboxylic Acids; Trinitrobenzenesulfonic Acid | 2000 |
Catalytic control and coupling efficiency of the Escherichia coli FoF1 ATP synthase: influence of the Fo sector and epsilon subunit on the catalytic transition state.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Biological Transport; Catalysis; Cysteine; Detergents; Dimethylamines; Enzyme Activation; Escherichia coli; Glutamic Acid; Hydrolysis; Kinetics; Lysine; Methionine; Mutagenesis, Site-Directed; Peptide Fragments; Proton-Translocating ATPases; Protons; Tyrosine | 2000 |
Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin.
Topics: Amino Acid Sequence; Conserved Sequence; Cysteine; Glycine; Lysine; Peptide Fragments; Protein Binding; Protein Subunits; Rhodopsin; Transducin | 2001 |
Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain.
Topics: Amino Acid Substitution; Androstadienes; Animals; Arginine; Blood Proteins; Cysteine; Enzyme Inhibitors; Glutamic Acid; Humans; Interleukin-2; Jurkat Cells; Lysine; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Sequence Homology, Amino Acid; Signal Transduction; T-Lymphocytes; Transfection; Wortmannin | 2001 |
Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue.
Topics: Acetic Acid; Alanine; Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cysteine; Deuterium; Escherichia coli; Formates; Gene Expression Regulation, Bacterial; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Pantothenic Acid; Recombinant Proteins; Sequence Alignment; Substrate Specificity | 2000 |
Effect of pressure processing on amino acid digestibility of meat and bone meal for poultry.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Biological Products; Cattle; Chickens; Cysteine; Digestion; Encephalopathy, Bovine Spongiform; Food Handling; Lysine; Male; Meat; Minerals; Pressure | 2000 |
Evaluation of lysine and methionine production in some Lactobacilli and yeasts from ogi.
Topics: Antimetabolites; Cysteine; Ethionine; Fermentation; Lactobacillus; Lysine; Methionine; Protein Synthesis Inhibitors; Yeasts; Zea mays | 2001 |
Role of hydrophobic residues in the C1b domain of protein kinase C delta on ligand and phospholipid interactions.
Topics: Amino Acid Sequence; Arginine; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Isoenzymes; Kinetics; Leucine; Ligands; Lipid Metabolism; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phorbol Esters; Phospholipids; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Tyrosine | 2001 |
"Lysine is the Lord", thought some scientists in regard to the group interacting with fluorescein isothiocyanate in ATP-binding sites of P-type ATPases but, is it not cysteine?
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Cell Membrane; Cysteine; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Hydrolysis; Lysine; Models, Chemical; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation | 2000 |
Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants.
Topics: Amino Acid Sequence; Animals; COS Cells; Cysteine; Disulfides; Endopeptidase K; Humans; Lysine; Maleimides; Models, Molecular; Molecular Sequence Data; Mutation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Retinitis Pigmentosa; Rhodopsin; Rod Opsins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship | 2001 |
Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent.
Topics: Amino Acid Sequence; Animals; Azides; Binding Sites; Cattle; COS Cells; Cross-Linking Reagents; Cysteine; Disulfides; Dithiothreitol; Ethylmaleimide; Guanosine Diphosphate; Light; Lysine; Maleimides; Models, Molecular; Molecular Sequence Data; Mutation; Photolysis; Protein Binding; Protein Structure, Secondary; Pyridines; Rhodopsin; Sepharose; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transducin; Trypsin; Ultraviolet Rays | 2001 |
Inhibitors of advanced glycation end product-associated protein cross-linking.
Topics: Animals; Carbon Radioisotopes; Cattle; Cross-Linking Reagents; Crystallins; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescence; Glucose; Glycation End Products, Advanced; Glycosylation; Lysine; Pyridoxal Phosphate; Sulfites; Tetroses; Thiamine Pyrophosphate | 2001 |
Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor.
Topics: Adrenergic beta-Agonists; Albuterol; Binding Sites; Cysteine; Detergents; Dobutamine; Epinephrine; Fluoresceins; Fluorescence; Fluorescent Dyes; Glucosides; GTP-Binding Proteins; Humans; Isoproterenol; Kinetics; Lysine; Micelles; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Adrenergic, beta-2; Stearic Acids | 2001 |
Conformation and polarity of the active site of xylanase I from Thermomonospora sp. as deduced by fluorescent chemoaffinity labeling. Site and significance of a histidine residue.
Topics: Actinomycetales; Affinity Labels; Amino Acids; Binding Sites; Circular Dichroism; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Enzyme Activation; Ethylmaleimide; Histidine; Hydroxymercuribenzoates; Indicators and Reagents; Kinetics; Lysine; Models, Chemical; o-Phthalaldehyde; Protease Inhibitors; Protein Binding; Protein Conformation; Sequence Analysis, Protein; Spectrometry, Fluorescence; Sulfhydryl Reagents; Time Factors; Trinitrobenzenesulfonic Acid; Urea; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 2001 |
Inhibition of lysine 2,3-aminomutase by the alternative substrate 4-thialysine and characterization of the 4-thialysyl radical intermediate.
Topics: Binding, Competitive; Clostridium; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Free Radicals; Intramolecular Transferases; Lysine; Molecular Conformation | 2001 |
Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Binding Sites; Blotting, Western; Cell Membrane; Chromatography, Gel; Collagen; COS Cells; Cross-Linking Reagents; Cysteine; Dimerization; Disulfides; Humans; Immunoblotting; Lysine; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Signal Transduction; Transfection; Tumor Cells, Cultured | 2001 |
Novel intra- and inter-molecular sulfinamide bonds in S100A8 produced by hypochlorite oxidation.
Topics: Amino Acid Sequence; Antigens, Differentiation; Aspartic Acid; Binding Sites; Calcium-Binding Proteins; Calgranulin A; Chromatography, High Pressure Liquid; Cyclohexanones; Cysteine; Dimerization; Disulfides; Dithiothreitol; Dose-Response Relationship, Drug; Hydrogen Peroxide; Hypochlorous Acid; Lysine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Neutrophils; Oxygen; Peptides; Peroxidase; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfenic Acids; Sulfur; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Amino acid transporters involved in luminal transport of mercuric conjugates of cysteine in rabbit proximal tubule.
Topics: Amino Acid Transport Systems; Animals; Carrier Proteins; Cells, Cultured; Cysteine; Epithelial Cells; Kidney Tubules, Proximal; Lysine; Mercury; Organomercury Compounds; Rabbits; Sodium; Stereoisomerism | 2001 |
Effect of ionic strength on the conformation of myosin subfragment 1-nucleotide complexes.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alkylation; Animals; Circular Dichroism; Cysteine; Lysine; Muscle, Skeletal; Myosin Subfragments; Nucleotides; Osmolar Concentration; Potassium; Protein Binding; Protein Conformation; Rabbits; Time Factors; Trinitrobenzenes; Tryptophan; Vanadates | 2001 |
Alkylation kinetics of proteins in preparation for two-dimensional maps: a matrix assisted laser desorption/ionization-mass spectrometry investigation.
Topics: Alkylation; Animals; Binding Sites; Cattle; Chickens; Cholic Acids; Cysteine; Electrophoresis, Gel, Two-Dimensional; Iodoacetamide; Kinetics; Lactalbumin; Lysine; Muramidase; Peptide Mapping; Proteins; Sodium Dodecyl Sulfate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2001 |
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myristic Acid; Plasmids; Protein Binding; Recombinant Proteins | 2001 |
The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p.
Topics: Conserved Sequence; COP9 Signalosome Complex; Cysteine; DNA-Binding Proteins; Genetic Complementation Test; Ligases; Lysine; Macromolecular Substances; Multiprotein Complexes; Mutation; Peptide Hydrolases; Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Signal Transduction; Transcription Factors; Ubiquitins | 2001 |
The juxtamembrane lysine and arginine residues of surfactant protein C precursor influence palmitoylation via effects on trafficking.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Base Sequence; Biological Transport, Active; Brefeldin A; CHO Cells; Cricetinae; Cysteine; DNA Primers; Endoplasmic Reticulum; Golgi Apparatus; Humans; Lysine; Molecular Sequence Data; Mutation; Palmitic Acid; Peptides; Pulmonary Surfactant-Associated Protein C; Pulmonary Surfactants; Recombinant Proteins; Subcellular Fractions | 2001 |
Residue-specific effects on slow inactivation at V787 in D2-S6 of Na(v)1.4 sodium channels.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Cysteine; Electrophysiology; Ethyl Methanesulfonate; Ion Channel Gating; Lysine; Membrane Potentials; Models, Biological; Muscle, Skeletal; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Sodium Channels | 2001 |
CFTR: covalent and noncovalent modification suggests a role for fixed charges in anion conduction.
Topics: Animals; Anions; Arginine; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Disulfides; Electric Conductivity; Ethyl Methanesulfonate; Female; Humans; Hydrogen-Ion Concentration; Lysine; Membrane Potentials; Mercaptoethanol; Mesylates; Models, Biological; Oocytes; Patch-Clamp Techniques; Perfusion; Xenopus | 2001 |
Rhodopsin-transducin interface: studies with conformationally constrained peptides.
Topics: Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Dose-Response Relationship, Drug; Leucine; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Monte Carlo Method; Mutation; Peptide Biosynthesis; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Rhodopsin; Spectrophotometry; Temperature; Transducin; Ultraviolet Rays; Valine | 2001 |
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Chromatography, High Pressure Liquid; Cysteine; Cystine; Disulfides; Electrophoresis, Polyacrylamide Gel; Frizzled Receptors; Glycosylation; Heparin; Humans; Lysine; Mass Spectrometry; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Netrin Receptors; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Proteins; Receptors, Cell Surface; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subtilisin; Time Factors; Xenopus | 2002 |
Evidence for an initiation site for hen lysozyme folding from the reduced form using its dissected peptide fragments.
Topics: Animals; Aspartic Acid; Binding Sites; Chickens; Chromatography, Ion Exchange; Circular Dichroism; Cysteine; Disulfides; Dose-Response Relationship, Drug; Glycine; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Muramidase; Mutation; Oxygen; Peptides; Protein Folding; Protein Structure, Tertiary | 2001 |
Specificity determining residues in ammonia- and glutamine-dependent carbamoyl phosphate synthetases.
Topics: Adenosine Triphosphate; Allosteric Site; Amino Acid Sequence; Ammonia; Animals; Binding Sites; Blotting, Western; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cysteine; Escherichia coli; Glutamic Acid; Glutamine; Humans; Kinetics; Leucine; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Binding; Protein Structure, Tertiary; Ranidae; Rats; Recombinant Proteins; Substrate Specificity | 2002 |
Actin cross-linking and inhibition of the actomyosin motor.
Topics: Actins; Actomyosin; Adenosine Triphosphatases; Animals; Cell Movement; Cross-Linking Reagents; Cysteine; Glutamine; In Vitro Techniques; Lysine; Models, Molecular; Muscle, Skeletal; Myosin Subfragments; Myosins; Protein Conformation; Rabbits | 2002 |
Regulation of thioredoxin peroxidase activity by C-terminal truncation.
Topics: Amino Acid Sequence; Antioxidants; Catalytic Domain; Cysteine; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Hydrogen Peroxide; Lysine; Molecular Sequence Data; Mutation; Neoplasm Proteins; Peptide Fragments; Peroxidases; Peroxiredoxins; Schizosaccharomyces; Sequence Deletion | 2002 |
Crystal structure of the human estrogen sulfotransferase-PAPS complex: evidence for catalytic role of Ser137 in the sulfuryl transfer reaction.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Estradiol; Lysine; Macromolecular Substances; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Phosphoadenosine Phosphosulfate; Protein Binding; Protein Conformation; Serine; Sulfates; Sulfotransferases | 2002 |
Free-thiol Cys331 exposed during activation process is critical for native tetramer structure of cathepsin C (dipeptidyl peptidase I).
Topics: Amino Acid Sequence; Animals; Cathepsin C; Cattle; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Enzyme Activation; Lysine; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Protein Conformation; Protein Folding; Protein Processing, Post-Translational; Spleen | 2002 |
Structural and conformational analysis of the oxidase to dehydrogenase conversion of xanthine oxidoreductase.
Topics: Animals; Cattle; Chromatography; Chromatography, High Pressure Liquid; Chymotrypsin; Cross-Linking Reagents; Cysteine; Disulfides; Electrophoresis, Gel, Two-Dimensional; Lysine; Methionine; Microscopy, Fluorescence; Oxidoreductases; Oxygen; Phenylalanine; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Sulfhydryl Compounds; Time Factors; Trypsin; Xanthine Dehydrogenase; Xanthine Oxidase | 2002 |
The local electrostatic environment determines cysteine reactivity of tubulin.
Topics: Acetamides; Animals; Cysteine; Electrons; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Ligands; Lysine; Mass Spectrometry; Models, Molecular; Palmitic Acids; Peptides; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Static Electricity; Sulfides; Time Factors; Trypsin; Tubulin | 2002 |
Characterization of binding and utilization of hemoglobin by Prevotella nigrescens.
Topics: Arginine; Bacterial Proteins; Catalase; Cysteine; Cytochrome c Group; Disaccharides; Globins; Hemoglobins; Hexoses; Histidine; Hot Temperature; Humans; Immunoblotting; Iron; Lactoferrin; Lysine; Prevotella; Protein Binding; Transferrin; Trypsin | 2002 |
Identification of the bacteria-binding peptide domain on salivary agglutinin (gp-340/DMBT1), a member of the scavenger receptor cysteine-rich superfamily.
Topics: Agglutination; Agglutinins; Amino Acid Sequence; Binding Sites; Calcium-Binding Proteins; Consensus Sequence; Cysteine; DNA-Binding Proteins; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Parotid Gland; Peptide Fragments; Polymorphism, Genetic; Protein Conformation; Receptors, Cell Surface; Saliva; Salivary Proteins and Peptides; Sequence Alignment; Sequence Homology, Amino Acid; Streptococcus mutans; Tumor Suppressor Proteins | 2002 |
Application of SCAM (substituted cysteine accessibility method) to gap junction intercellular channels.
Topics: Amino Acid Sequence; Animals; Connexins; Cysteine; Gap Junction beta-1 Protein; Gap Junctions; Ion Channel Gating; Lysine; Maleimides; Models, Molecular; Oocytes; Patch-Clamp Techniques; Protein Structure, Secondary; Rats; Xenopus laevis | 2001 |
Chemical-modification rescue assessed by mass spectrometry demonstrates that gamma-thia-lysine yields the same activity as lysine in aldolase.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Fourier Analysis; Fructose-Bisphosphate Aldolase; Lysine; Molecular Sequence Data; Mutation; Spectrometry, Mass, Electrospray Ionization | 2002 |
Disulfide exchange in domain 2 of CD4 is required for entry of HIV-1.
Topics: Arsenicals; Biotin; CD4 Antigens; CD4-Positive T-Lymphocytes; Cysteine; Glutathione; HIV-1; Humans; Immunoblotting; Lysine; Maleimides; Mutation; Oxidation-Reduction; Protein Structure, Tertiary; Receptors, HIV; Succinimides; Sulfhydryl Compounds; Thioredoxins | 2002 |
Characterization of bacterial homocitrate synthase involved in lysine biosynthesis.
Topics: Arginine; Cysteine; Feedback, Physiological; Kinetics; Lysine; Oxo-Acid-Lyases; Substrate Specificity; Temperature; Thermus thermophilus | 2002 |
Disulfide bond switches.
Topics: Arsenicals; Biotin; CD4 Antigens; CD4-Positive T-Lymphocytes; Cysteine; Disulfides; Glutathione; HIV-1; Humans; Immunoblotting; Lysine; Maleimides; Mutation; Oxidation-Reduction; Protein Structure, Tertiary; Receptors, HIV; Succinimides; Sulfhydryl Compounds; Thioredoxins | 2002 |
Complete replacement of basic amino acid residues with cysteines in Rickettsia prowazekii ATP/ADP translocase.
Topics: Amino Acids, Basic; Arginine; Cysteine; Cytoplasm; Kinetics; Lysine; Mesylates; Mitochondrial ADP, ATP Translocases; Mutagenesis, Site-Directed; Mutation; Periplasm; Protein Structure, Tertiary; Rickettsia prowazekii | 2002 |
Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms.
Topics: Alanine Transaminase; Binding Sites; Crystallization; Crystallography, X-Ray; Cysteine; D-Alanine Transaminase; Escherichia coli Proteins; Humans; Isoenzymes; Isoleucine; Lysine; Mitochondria; Models, Molecular; Oxo-Acid-Lyases; Protein Conformation; Protein Structure, Secondary; Pyridoxamine; Schiff Bases; Substrate Specificity; Transaminases; Valine | 2002 |
Structural roles of cysteine 50 and cysteine 230 residues in Arabidopsis thaliana S-adenosylmethionine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Amino Acid Sequence; Arabidopsis; Base Sequence; Circular Dichroism; Cloning, Molecular; Cysteine; DNA, Complementary; DNA, Plant; Enzyme Stability; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Temperature | 2002 |
Pore topology of the hyperpolarization-activated cyclic nucleotide-gated channel from sea urchin sperm.
Topics: Amino Acid Sequence; Animals; Biophysical Phenomena; Biophysics; Chlorine; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Ions; Lysine; Male; Models, Molecular; Molecular Sequence Data; Oocytes; Potassium Channels; Potassium Chloride; RNA, Complementary; Sea Urchins; Spermatozoa; Xenopus laevis | 2002 |
A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity.
Topics: Alcohol Dehydrogenase; alpha-Crystallin A Chain; alpha-Glucosidases; Animals; Arginine; Aspartic Acid; Circular Dichroism; Cysteine; Glycine; Humans; Lysine; Molecular Weight; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Rats; Static Electricity; Urea | 2002 |
Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal.
Topics: Aldehydes; Amino Acids; Arginine; Cysteine; Histidine; Kinetics; Lipid Peroxidation; Lysine; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2002 |
In situ alkylation with acrylamide for identification of cysteinyl residues in proteins during one- and two-dimensional sodium dodecyl sulphate-polyacrylamide gel electrophoresis.
Topics: Acrylamide; Alkylation; Animals; Cattle; Cell Fractionation; Cysteine; Electrophoresis, Polyacrylamide Gel; Lysine; Mice; Mitochondria, Liver; Muramidase; Proteins; Serum Albumin, Bovine | 2002 |
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea | 2002 |
Helix packing in subunit a of the Escherichia coli ATP synthase as determined by chemical labeling and proteolysis of the cysteine-substituted protein.
Topics: Amino Acid Sequence; Amino Acid Substitution; Copper; Cysteine; Endopeptidases; Escherichia coli Proteins; Hydrolysis; Lysine; Maleimides; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Organometallic Compounds; Peptide Fragments; Phenanthrolines; Protein Structure, Secondary; Protein Subunits; Proton-Translocating ATPases | 2003 |
Conserved residues R420 and Q428 in a cytoplasmic loop of the citrate/malate transporter CimH of Bacillus subtilis are accessible from the external face of the membrane.
Topics: Arginine; Bacillus subtilis; Bacterial Proteins; Calcium; Carrier Proteins; Cell Membrane; Cell Membrane Permeability; Citric Acid; Conserved Sequence; Cysteine; Cytoplasm; Ethyl Methanesulfonate; Ethylmaleimide; Glutamine; Hydroxy Acids; Lysine; Malates; Mutagenesis, Site-Directed; Organic Anion Transporters; Plasmids; Substrate Specificity | 2003 |
Coupling of contact sensitizers to thiol groups is a key event for the activation of monocytes and monocyte-derived dendritic cells.
Topics: Acetates; Anti-Infective Agents; Antioxidants; Cysteine; Dendritic Cells; Ethylmaleimide; Humans; Interleukin-1; Lysine; Maleimides; MAP Kinase Signaling System; Monocytes; Phosphorylation; Picryl Chloride; Succinimides; Sulfhydryl Compounds; Sulfhydryl Reagents; Thiazoles; Tyrosine | 2003 |
Binding of ATP as well as tetrahydrofolate induces conformational changes in Lactobacillus casei folylpolyglutamate synthetase in solution.
Topics: Adenosine Triphosphate; Aspartic Acid; Circular Dichroism; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Lacticaseibacillus casei; Lysine; Mesylates; Mutagenesis, Site-Directed; Peptide Synthases; Protein Binding; Protein Conformation; Solutions; Spin Labels; Substrate Specificity; Tetrahydrofolates | 2003 |
Ruthenium red inhibits TASK-3 potassium channel by interconnecting glutamate 70 of the two subunits.
Topics: Animals; Arginine; Coloring Agents; Cysteine; Dimerization; Glutamic Acid; Humans; Lysine; Mice; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Potassium Channels; Potassium Channels, Tandem Pore Domain; Ruthenium Red | 2003 |
In vitro refolding of human proinsulin. Kinetic intermediates, putative disulfide-forming pathway folding initiation site, and potential role of C-peptide in folding process.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; C-Peptide; Chromatography, High Pressure Liquid; Circular Dichroism; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Humans; Kinetics; Lysine; Molecular Sequence Data; Molecular Weight; Oxygen; Peptide Mapping; Peptides; Proinsulin; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Swine; Time Factors | 2003 |
Gonadotropin releasing hormone (GnRH) modulates odorant responses in the peripheral olfactory system of axolotls.
Topics: Ambystoma mexicanum; Animals; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Lysine; Male; Methionine; Odorants; Olfactory Mucosa; Olfactory Receptor Neurons | 2003 |
Late-onset form of beta-electron transfer flavoprotein deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Carnitine; Cysteine; DNA Mutational Analysis; Electron-Transferring Flavoproteins; Electrons; Exons; Female; Fibroblasts; Gas Chromatography-Mass Spectrometry; Gene Deletion; Glutarates; Humans; Infant, Newborn; Iron-Sulfur Proteins; Lysine; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Phenotype | 2003 |
Genetic, clinical and pathological studies of CADASIL in Japan: a partial contribution of Notch3 mutations and implications of smooth muscle cell degeneration for the pathogenesis.
Topics: Age of Onset; Arginine; Arteries; Brain; Cerebral Arterial Diseases; Cerebral Infarction; Cysteine; DNA Mutational Analysis; Family Health; Female; Humans; Immunohistochemistry; Japan; Lysine; Magnetic Resonance Imaging; Male; Microscopy, Electron; Muscular Diseases; Mutation; Phenylalanine; Proto-Oncogene Proteins; Receptor, Notch3; Receptors, Cell Surface; Receptors, Notch | 2003 |
A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Cell Line; Chlorine; Cysteine; Disulfides; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Genetic Vectors; Glycine; Humans; Hydrogen-Ion Concentration; Ion Channels; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Receptors, Glycine; Taurine | 2003 |
The Cys-Xaa-His metal-binding motif: [N] versus [S] coordination and nickel-mediated formation of cysteinyl sulfinic acid.
Topics: Alkylation; Amino Acid Motifs; Chromatography, High Pressure Liquid; Copper; Cysteine; Glycine; Histidine; Humans; Hydrogen-Ion Concentration; Lysine; Metalloproteins; Metals; Molecular Structure; Neurotransmitter Agents; Nickel; Oxidation-Reduction; Peptides | 2003 |
Characterization of a lactose permease mutant that binds IIAGlc in the absence of ligand.
Topics: Amino Acid Substitution; Binding Sites; Cysteine; Escherichia coli; Escherichia coli Proteins; Fluorescence Polarization; Galactosides; Iodine Radioisotopes; Ligands; Lysine; Membrane Transport Proteins; Monosaccharide Transport Proteins; Mutagenesis, Insertional; Phosphoenolpyruvate Sugar Phosphotransferase System; Protein Binding; Protein Transport; Substrate Specificity; Symporters | 2003 |
Structural basis for the product specificity of histone lysine methyltransferases.
Topics: Catalytic Domain; Cysteine; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Macromolecular Substances; Methyltransferases; Models, Molecular; Molecular Structure; Neurospora crassa; Peptides; Protein Methyltransferases; Protein Structure, Tertiary; S-Adenosylhomocysteine; Sulfur; Zinc | 2003 |
Acetylation of the HIV-1 Tat protein: an in vitro study.
Topics: Acetylation; Acetyltransferases; Amino Acid Sequence; Arginine; Cysteine; Gene Products, tat; Histone Acetyltransferases; In Vitro Techniques; Lysine; Molecular Sequence Data; Peptides; Protein Processing, Post-Translational; Saccharomyces cerevisiae Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2003 |
Fourier transform IR attenuated total reflectance spectroscopy studies of cysteine-induced changes in secondary conformations of bovine serum albumin after UV-B irradiation.
Topics: Amino Acids; Animals; Cattle; Cysteine; Lipids; Lysine; Protein Binding; Protein Conformation; Protein Structure, Secondary; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Time Factors; Ultraviolet Rays | 2003 |
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Topics: Amino Acid Sequence; Antigens, Surface; Biotinylation; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Lymphocyte Antigen 96; Lysine; Membrane Glycoproteins; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Molecular Sequence Data; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface; Recombinant Proteins; Sequence Homology, Amino Acid; Signal Transduction; Toll-Like Receptor 4; Toll-Like Receptors; Transfection; Tyrosine | 2003 |
Spatial and dynamic interactions between phospholamban and the canine cardiac Ca2+ pump revealed with use of heterobifunctional cross-linking agents.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cell Line; Cross-Linking Reagents; Cysteine; Cystine; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Insecta; Lysine; Microsomes; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis; Peptides; Point Mutation; Protein Binding; Protein Conformation; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sulfhydryl Compounds; Temperature; Thapsigargin; Time Factors | 2003 |
Studies of hypersensitivity to low molecular weight substances. II. Reactions of some allergenic substituted dinitrobenzenes with cysteine or cystine of skin proteins.
Topics: Allergens; Animals; Cattle; Cysteine; Cystine; Dinitrobenzenes; Dinitrofluorobenzene; Disulfides; Guinea Pigs; Humans; Hypersensitivity; Immune System Diseases; Lysine; Molecular Weight; Nitrobenzenes; Proteins; Skin; Sulfenic Acids; Sulfhydryl Compounds | 1953 |
Inhibition of lysine utilization in bacteria by S-(beta-aminoethyl) cysteine and its reversal by lysine peptides.
Topics: Bacteria; Cysteine; Lactobacillus; Leuconostoc; Lysine; Peptides | 1958 |
[Dinitrophenylene-bis-amino acids from cysteine, also from glycine, lysine and tyrosine].
Topics: Amino Acids; Cysteine; Glycine; Lysine; Nitrobenzenes; Tyrosine | 1958 |
The mitotic and radioprotective effect of cysteine and lysine in rat.
Topics: Animals; Cell Division; Cysteine; Lysine; Radiation Protection; Rats | 1960 |
Biosynthesis of cephalosporin C.
Topics: 2-Aminoadipic Acid; Anti-Bacterial Agents; Cephalosporins; Cysteine; Lysine; Methionine | 1962 |
Inhibition of lysine and lysine peptide utilization in bacteria by peptides of S-(beta-aminoethyl)-cysteine.
Topics: Bacteria; Biochemical Phenomena; Cysteine; Lysine; Peptides | 1961 |
Amino acids, amino sugars and sugars present in the cell wall of some strains of Streptococcus pyogenes.
Topics: Alanine; Amino Acids; Amino Sugars; Arginine; Aspartic Acid; Cell Wall; Cysteine; Glucosamine; Glutamates; Glycine; Hexosamines; Isoleucine; Leucine; Lysine; Serine; Streptococcus pyogenes; Threonine; Valine | 1962 |
Enzymic decarboxylation of S-(2-aminoethyl) cysteine.
Topics: Biochemical Phenomena; Cysteine; Decarboxylation; Humans; Lyases; Lysine | 1962 |
Independence of amounts of incorporation of amino-acids into histones on the aminoacid composition of these proteins.
Topics: Amino Acids; Aspartic Acid; Cysteine; Histones; Lysine; Methionine; Proteins | 1963 |
GAS CHROMATOGRAPHY OF THE METHYL ESTERS OF THE AMINO ACIDS AS THE FREE BASE AND BY DISSOCIATION OF THEIR ACID SALTS.
Topics: Acetates; Amino Acids; Aspartic Acid; Chlorides; Chromatography; Chromatography, Gas; Cysteine; Cystine; Esters; Hydroxyproline; Ion Exchange Resins; Leucine; Lysine; Phenylalanine; Proline; Research; Salts; Serine | 1963 |
[RESEARCH ON THE NUTRITION OF ERWINIA CAROTOVORA].
Topics: Alanine; Aminobutyrates; Ammonium Compounds; Arginine; Asparagine; Aspartic Acid; Boron; Calcium; Cobalt; Copper; Creatine; Creatinine; Culture; Culture Media; Cysteine; Cystine; Erwinia; Glutamates; Glycine; Iron; Lysine; Magnesium; Manganese; Methionine; Minerals; Molybdenum; Pectobacterium carotovorum; Proteins; Quaternary Ammonium Compounds; Tryptophan; Tyrosine; Zinc | 1963 |
NUTRITION STUDIES IN NEW GUINEA.
Topics: Adolescent; Anthropology; Arachis; Black People; Blood Chemical Analysis; Blood Proteins; Child; Cholesterol; Creatine; Creatinine; Cysteine; Growth; Humans; Lysine; Methionine; New Guinea; Nitrogen; Nutrition Surveys; Nutritional Status; Plants, Edible; Protein Deficiency; Skeleton; Statistics as Topic; Urine | 1964 |
SPECIFIC INHIBITION OF CONTACT DERMATITIS TO DINITROCHLOROBENZENE IN GUINEA PIGS BY INJECTION OF HAPTENS AND PROTEIN CONJUGATES.
Topics: Aniline Compounds; Animals; Antigens; Cysteine; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzene; Dinitrophenols; Glutathione; Guinea Pigs; Haptens; Lysine; Nitrobenzenes; Proteins; Research; Skin Tests; Sulfonic Acids; Toxicology | 1964 |
POLYNUCLEOTIDE ANALOGUES. II. STIMULATION OF AMINO ACID INCORPORATION BY POLYNUCLEOTIDE ANALOGUES.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Glycine; Isoleucine; Leucine; Lysine; Pharmacology; Phenylalanine; Polynucleotides; Proline; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Uracil Nucleotides; Valine | 1964 |
SYNTHESIS AND CONFORMATION OF A COPOLYMER OF E-CARBOBENZOXY-L-LYSINE AND S-CARBOBENZOXYL-L-CYSTEINE.
Topics: Chemical Phenomena; Chemistry; Chloroform; Cysteine; Lysine; Molecular Conformation; Peptides; Polymers; Research; Spectrum Analysis | 1964 |
BIOSYNTHESIS OF BACITRACIN. I. FORMATION OF BACITRACIN BY A SUBCELLULAR FRACTION OF BACILLUS LICHENIFORMIS.
Topics: Asparagine; Aspartic Acid; Bacillus; Bacitracin; Carbon Isotopes; Chromatography; Cysteine; Cystine; Glutamates; Glutathione; Histidine; Isoleucine; Lysine; Metabolism; Micrococcus; Ornithine; Phenylalanine; Research; Subcellular Fractions; Sulfhydryl Compounds; Sulfur Isotopes | 1964 |
NUTRITIONAL FACTORS RELATING TO GROWTH AND OXYTETRACYCLINE FORMATION BY STREPTOMYCES RIMOSUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Cysteine; Cystine; Glutamine; Glycine; Histidine; Isoleucine; Lysine; Metabolism; Methionine; Oxytetracycline; Research; Serine; Streptomyces; Streptomyces rimosus | 1964 |
SPECIFICITY OF PEPTIDASES. HYDROLYSIS BY TRYPSIN, PAPAIN AND CATHEPSIN B OF SUBSTRATES CONTAINING LYSINE, 4-THIALYSINE OR 4-OXALYSINE.
Topics: Amino Acids, Dicarboxylic; Cathepsin B; Cathepsins; Chemical Phenomena; Chemistry; Cysteine; Hydrolysis; Kinetics; Lysine; Papain; Peptide Hydrolases; Research; Trypsin | 1964 |
N-EPSILON-(DL-2-AMINO-2-CARBOXYETHYL)-L-LYSINE, A NEW AMINO ACID FORMED ON ALKALINE TREATMENT OF PROTEINS.
Topics: Albumins; Amino Acid Oxidoreductases; Amino Acids; Ammonia; Animals; Carboxy-Lyases; Cattle; Chromatography; Chymotrypsin; Cysteine; Cystine; Dipeptides; Formaldehyde; Lysine; Muramidase; Papain; Protein Hydrolysates; Proteins; Research; Ribonucleases | 1964 |
RECOMBINATION BETWEEN NOCARDIA ERYTHROPOLIS AND NOCARDIA CANICRURIA.
Topics: Adenine; Alanine; Anti-Bacterial Agents; Arginine; Cysteine; Cystine; Drug Resistance; Drug Resistance, Microbial; Glycine; Guanine; Histidine; Hypoxanthines; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Mutation; Nocardia; Recombination, Genetic; Research; Streptomycin; Valine; Xanthines | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
CYSTINURIA: EFFECT OF D-PENICILLAMINE ON PLASMA AND URINARY CYSTINE CONCENTRATIONS.
Topics: Arginine; Blood; Cysteine; Cystine; Cystinuria; Drug Therapy; Humans; Lysine; Penicillamine; Sulfides; Urine | 1965 |
EFFECT OF PENICILLAMINE ON CYSTINURIA.
Topics: Arginine; Body Fluids; Cysteine; Cystinuria; Drug Therapy; Homocysteine; Humans; Lysine; Ornithine; Penicillamine; Urine | 1965 |
TISSUE EOSINOPHILS OF RAT UNDER THE INFLUENCE OF CYSTEINE, LYSINE AND X-IRRADIATION.
Topics: Adrenocorticotropic Hormone; Colon; Cortisone; Cysteine; Duodenum; Eosinophils; Leukocyte Count; Lysine; Radiation Effects; Rats; Research; Skin | 1965 |
N-ACETYLATION OF 3-PHOSPHOGLYCERALDEHYDE DEHYDROGENASE BY SUBSTRATES.
Topics: Acetates; Acetylation; Autoradiography; Carbon Isotopes; Chemical Phenomena; Chemistry; Cysteine; Glyceraldehyde 3-Phosphate; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Lysine; Peptides; Phosphates; Research | 1965 |
Formation of a ribosomal lesion in rabbit reticulocytes by the lysine antagonist, S-(beta-aminoethyl) cysteine.
Topics: Animals; Blood Proteins; Cysteine; Erythrocytes; Humans; Lysine; Nucleoproteins; Rabbits; Reticulocytes; Ribosomes | 1962 |
Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor.
Topics: Acetylcholine; Amino Acid Sequence; Carrier Proteins; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Glycine; Humans; Indicators and Reagents; Ions; Ligands; Lysine; Mesylates; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Glycine; Sequence Homology, Amino Acid; Taurine; Time Factors | 2003 |
Expression and purification of enzymatically active forms of the human lysyl oxidase-like protein 4.
Topics: Amine Oxidase (Copper-Containing); Amino Acid Oxidoreductases; Aminopropionitrile; Benzylamines; Copper; Crystallography, X-Ray; Cysteine; Escherichia coli; Humans; Lysine; Models, Genetic; Placenta; Plasmids; Protein Binding; Protein Folding; Protein Structure, Tertiary; Protein-Lysine 6-Oxidase; Quinones; Receptors, Cytokine; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Temperature; Ultraviolet Rays | 2003 |
Topological and functional study of subunit h of the F1Fo ATP synthase complex in yeast Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cross-Linking Reagents; Cysteine; Enzyme Activation; Intracellular Membranes; Lysine; Maleimides; Mitochondria; Mitochondrial Proton-Translocating ATPases; Molecular Sequence Data; Peptide Fragments; Protein Processing, Post-Translational; Protein Subunits; Saccharomyces cerevisiae Proteins; Sodium-Potassium-Exchanging ATPase; Succinimides; Vacuolar Proton-Translocating ATPases | 2003 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
Spatial proximity between a photolabile residue in position 19 of salmon calcitonin and the amino terminus of the human calcitonin receptor.
Topics: Amino Acid Sequence; Animals; Calcitonin; Cell Membrane; COS Cells; Cross-Linking Reagents; Cyanogen Bromide; Cyclic AMP; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Endopeptidases; Ligands; Lysine; Metalloendopeptidases; Methionine; Molecular Sequence Data; Mutagenesis; Mutation; Oxygen; Peptides; Phenylalanine; Photoaffinity Labels; Point Mutation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Receptors, Calcitonin; Salmon; Transfection | 2004 |
Nonorthologous replacement of lysyl-tRNA synthetase prevents addition of lysine analogues to the genetic code.
Topics: Bacillus subtilis; Borrelia burgdorferi; Cysteine; Drug Resistance, Bacterial; Enzyme Inhibitors; Evolution, Molecular; Genes, Bacterial; Genetic Code; Genomics; Isoenzymes; Lysine; Lysine-tRNA Ligase; RNA, Transfer, Lys; Species Specificity | 2003 |
Mechanism underlying cytotoxicity of thialysine, lysine analog, toward human acute leukemia Jurkat T cells.
Topics: Apoptosis; bcl-X Protein; Caspases; Cell Cycle; Cell Survival; Cysteine; Cytochromes c; Enzyme Activation; Humans; Jurkat Cells; Leukemia; Lysine; Mitochondria; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2003 |
Detection of alpha-helical coiled-coil dimer formation by spin-labeled synthetic peptides: a model parallel coiled-coil peptide and the antiparallel coiled coil formed by a replica of the ProP C-terminus.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cysteine; Dimerization; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Structure, Secondary; Protein Structure, Tertiary; Spin Labels; Symporters | 2003 |
Cross-talk between Cys34 and lysine residues in human serum albumin revealed by N-homocysteinylation.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Homocysteine; Humans; Hydrolysis; Lysine; Oxidation-Reduction; Serum Albumin | 2004 |
Divergence in noncognate amino acid recognition between class I and class II lysyl-tRNA synthetases.
Topics: Amino Acids; Anti-Infective Agents; Bacillus subtilis; Binding Sites; Cell Division; Chromatography, Thin Layer; Cysteine; Escherichia coli; gamma-Aminobutyric Acid; Kinetics; Lysine; Lysine-tRNA Ligase; Models, Molecular; Plasmids; Protein Binding; Substrate Specificity; Time Factors | 2004 |
Effect of Porphyromonas gingivalis vesicles on coaggregation of Staphylococcus aureus to oral microorganisms.
Topics: Actinomyces; Arginine; Bacterial Adhesion; Biofilms; Candida albicans; Cell Membrane Structures; Cysteine; Dental Plaque; Fusobacterium nucleatum; Gingiva; Lysine; Methicillin Resistance; Porphyromonas gingivalis; Staphylococcus aureus; Streptococcus | 2003 |
Structure of the scorpion toxin BmBKTtx1 solved from single wavelength anomalous scattering of sulfur.
Topics: Amino Acid Sequence; Amino Acids; Animals; Crystallography, X-Ray; Cysteine; Disulfides; Electrons; Insect Proteins; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Neurotoxins; Potassium Channels; Protein Conformation; Protein Folding; Scattering, Radiation; Scorpion Venoms; Scorpions; Static Electricity; Sulfur; X-Rays | 2004 |
The ionic track in the F1-ATPase from the thermophilic Bacillus PS3.
Topics: Adenosine Diphosphate; Amino Acid Substitution; Arginine; Bacillus; Bacterial Proton-Translocating ATPases; Catalytic Domain; Copper; Cysteine; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Lysine; Methylation; Mutagenesis, Site-Directed; Protein Subunits; Sodium-Potassium-Exchanging ATPase; Temperature | 2004 |
WWP1-dependent ubiquitination and degradation of the lung Krüppel-like factor, KLF2.
Topics: Animals; Cysteine; Cysteine Endopeptidases; Kruppel-Like Transcription Factors; Lysine; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Trans-Activators; Ubiquitin-Protein Ligases; Ubiquitins | 2004 |
Characterization of human UDP-glucose dehydrogenase. CYS-276 is required for the second of two successive oxidations.
Topics: Binding Sites; Catalytic Domain; Cysteine; Humans; Lysine; Oxidation-Reduction; Protein Conformation; Streptococcus pyogenes; Structure-Activity Relationship; Uridine Diphosphate Glucose Dehydrogenase | 2004 |
Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3.
Topics: Alanine; Amino Acid Sequence; Blood Platelets; Cell Line; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; DNA, Complementary; Fibrinogen; Flow Cytometry; Humans; Integrin alphaVbeta3; Lysine; Models, Molecular; Models, Statistical; Molecular Sequence Data; Mutation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Software; Structure-Activity Relationship; Thrombasthenia; Transfection | 2004 |
Activation of hemolysin toxin: relationship between two internal protein sites of acylation.
Topics: Acylation; Amino Acid Sequence; Arginine; Bacterial Toxins; Cloning, Molecular; Cysteine; Escherichia coli Proteins; Hemolysin Proteins; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Precursors; Sequence Deletion; Substrate Specificity | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Evidence for a proton transfer network and a required persulfide-bond-forming cysteine residue in Ni-containing carbon monoxide dehydrogenases.
Topics: Alanine; Aldehyde Oxidoreductases; Asparagine; Bacterial Proteins; Biological Transport; Catalysis; Clostridium; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Nickel; Protons; Serine; Sulfides | 2004 |
Resolution of Cys and Lys labeling of alpha-crystallin with site-sensitive fluorescent 3-hydroxyflavone dye.
Topics: alpha-Crystallins; Cysteine; Flavonoids; Fluorescent Dyes; Lysine; Molecular Structure; Sensitivity and Specificity; Spectrometry, Fluorescence; Staining and Labeling | 2004 |
Roles of cysteine 161 and tyrosine 154 in the lecithin-retinol acyltransferase mechanism.
Topics: Acyltransferases; Amino Acid Sequence; Animals; Binding Sites; Cattle; Cysteine; Humans; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Sequence Alignment; Tyrosine; Viral Proteins | 2004 |
Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs.
Topics: Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Constitutive Androstane Receptor; Cysteine; Dimerization; Drug Stability; Glutamic Acid; Humans; Isoleucine; Leucine; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction; Structure-Activity Relationship; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2004 |
The importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins.
Topics: Amino Acid Motifs; Bacterial Proteins; beta-Lactamases; Binding Sites; Carrier Proteins; Catalysis; Cloning, Molecular; Cysteine; Escherichia coli; Genetic Vectors; Glutamic Acid; Hexosyltransferases; Hydrogen-Ion Concentration; Ions; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Muramoylpentapeptide Carboxypeptidase; Mutation; Penicillin-Binding Proteins; Peptidyl Transferases; Protein Binding; Protons; Serine; Thermodynamics | 2004 |
Development of a peptide reactivity assay for screening contact allergens.
Topics: Algorithms; Allergens; Amino Acids; Animals; Calibration; Chromatography, High Pressure Liquid; Cysteine; Dermatitis, Allergic Contact; Female; Glutathione; Histidine; Kinetics; Local Lymph Node Assay; Lysine; Mice; Mice, Inbred CBA; Peptides; Skin Tests; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 2004 |
Mapping of factor XIII solvent accessibility as a function of activation state using chemical modification methods.
Topics: Acetic Anhydrides; Acetylation; Alkylation; Amino Acid Sequence; Cysteine; Ethylmaleimide; Factor XIII; Factor XIIIa; Humans; Hydrolysis; Intercellular Signaling Peptides and Proteins; Iodoacetamide; Lysine; Molecular Sequence Data; Peptide Mapping; Peptides; Solutions; Solvents; Trypsin | 2004 |
Model of glycoprotein hormone receptor ligand binding and signaling.
Topics: Amino Acid Sequence; Animals; Binding Sites; Callithrix; COS Cells; Cysteine; Dimerization; Disulfides; Dose-Response Relationship, Drug; Epitopes; Humans; Leucine; Ligands; Lysine; Models, Biological; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptors, Cell Surface; Receptors, FSH; Salmon; Signal Transduction; Tyrosine; Ubiquitin-Protein Ligases | 2004 |
The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Biochemistry; Carbohydrates; Colorimetry; Copper; Cysteine; Fructose; Glucose; Glutamic Acid; Glycine max; Hot Temperature; Hydrogen-Ion Concentration; Ions; Iron; Isoleucine; Leucine; Lysine; Maltose; Metals; Models, Chemical; Phenylalanine; Proline; Serine; Sodium Chloride; Temperature; Time Factors; Valine; Xylose | 2004 |
Trans-editing of Cys-tRNAPro by Haemophilus influenzae YbaK protein.
Topics: Amino Acyl-tRNA Synthetases; Bacterial Proteins; Cysteine; Cystine; Haemophilus influenzae; Lysine; Protein Structure, Tertiary; RNA Editing; RNA, Transfer; RNA, Transfer, Amino Acyl; RNA, Transfer, Pro; Time Factors | 2004 |
Responses of growing broilers to diets with increased sulfur amino acids to lysine ratios at two dietary protein levels.
Topics: Amino Acids, Sulfur; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cysteine; Diet; Dietary Proteins; Digestion; Lysine; Male; Methionine; Regression Analysis; Weight Gain | 2004 |
Response to lysine intake in composition of body weight gain and efficiency of lysine utilization of growing male chickens from two genotypes.
Topics: Amino Acids; Animals; Body Composition; Chickens; Cysteine; Energy Metabolism; Genotype; Glycine; Isoleucine; Lipid Metabolism; Lysine; Male; Methionine; Proline; Proteins; Serine; Weight Gain | 2004 |
Cross-metathesis coupling of sugars and fatty acids to lysine and cysteine.
Topics: Alkenes; Carbohydrates; Catalysis; Cysteine; Fatty Acids; Lysine; Molecular Structure | 2004 |
Effects of a novel disulfide bond and engineered electrostatic interactions on the thermostability of azurin.
Topics: Arginine; Aspartic Acid; Azurin; Calorimetry, Differential Scanning; Copper; Crystallography, X-Ray; Cysteine; Disulfides; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Protein Denaturation; Pseudomonas aeruginosa; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry; Static Electricity; Thermodynamics; Zinc | 2004 |
Palmitoylation of inducible nitric-oxide synthase at Cys-3 is required for proper intracellular traffic and nitric oxide synthesis.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antifungal Agents; Biological Transport; Boron Compounds; Brefeldin A; Cell Line; Cells, Cultured; Cloning, Molecular; COS Cells; Cysteine; Escherichia coli; Fluorescent Dyes; Golgi Apparatus; Green Fluorescent Proteins; Hydroxylamine; Lysine; Mice; Molecular Sequence Data; Monensin; Mutagenesis, Site-Directed; Mutation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Palmitic Acid; Proline; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Time Factors; Transfection | 2004 |
Glycation-induced inactivation of NADP(+)-dependent isocitrate dehydrogenase: implications for diabetes and aging.
Topics: Aging; Animals; Antioxidants; Cell Line; Cysteine; Diabetes Mellitus; Fructose; Glucose; Glycosylation; Humans; Isocitrate Dehydrogenase; Lysine; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats | 2004 |
Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration.
Topics: Aldehyde Oxidase; Arabidopsis; Arabidopsis Proteins; Bacterial Proteins; Binding Sites; Catalysis; Coenzymes; Cysteine; Cytosol; Fluorescent Dyes; Genetic Vectors; Iron-Sulfur Proteins; Kinetics; Lyases; Lysine; Metalloproteins; Molybdenum; Molybdenum Cofactors; Mutagenesis, Site-Directed; Naphthalenesulfonates; Pichia; Plant Proteins; Protein Binding; Protein Structure, Tertiary; Pteridines; Pyridoxal Phosphate; Selenocysteine; Spectrophotometry; Substrate Specificity; Sulfides; Sulfurtransferases; Xanthine Dehydrogenase | 2005 |
Endoproteolytic cleavage of human thyroperoxidase: role of the propeptide in the protein folding process.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Arginine; Autoantigens; Biotinylation; Brefeldin A; CHO Cells; Cricetinae; Cysteine; Cytoplasm; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Furin; Gene Deletion; Glycosylation; Heme; Humans; Immunoprecipitation; Iodide Peroxidase; Iron-Binding Proteins; Lysine; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Models, Genetic; Molecular Chaperones; Molecular Sequence Data; Monensin; Mutagenesis; Mutagenesis, Site-Directed; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Peptides; Protein Folding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Thyroid Gland; Time Factors; Transfection | 2005 |
Sequence and structural duality: designing peptides to adopt two stable conformations.
Topics: Amino Acid Sequence; Circular Dichroism; Cysteine; Hydrophobic and Hydrophilic Interactions; Leucine Zippers; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Weight; Oligopeptides; Peptides; Protein Conformation; Protein Engineering | 2004 |
Evidence for proximal cysteine and lysine residues at or near the active site of arginine kinase of Stichopus japonicus.
Topics: Amino Acid Sequence; Arginine Kinase; Binding Sites; Circular Dichroism; Cysteine; Electrophoresis, Polyacrylamide Gel; Kinetics; Lysine; Molecular Sequence Data; Protein Denaturation; Sequence Homology, Amino Acid; Stichopus | 2004 |
S-adenosylhomocysteine hydrolase from the archaeon Pyrococcus furiosus: biochemical characterization and analysis of protein structure by comparative molecular modeling.
Topics: Adenosine; Adenosylhomocysteinase; Amino Acid Sequence; Catalysis; Cloning, Molecular; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Homocysteine; Hot Temperature; Kinetics; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrococcus; Pyrococcus furiosus; Recombinant Proteins; Sequence Homology, Amino Acid; Sulfolobus solfataricus; Temperature; Threonine | 2005 |
How to hide zinc in a small protein.
Topics: Amino Acid Sequence; Bacteria; Cadmium; Cysteine; Dimerization; Histidine; Ligands; Lysine; Metallothionein; Molecular Sequence Data; Protein Binding; Protein Folding; Proteins; Sequence Alignment; Sulfhydryl Compounds; Sulfides; Zinc; Zinc Compounds; Zinc Fingers | 2005 |
BmP09, a "long chain" scorpion peptide blocker of BK channels.
Topics: Adrenal Medulla; Amino Acid Sequence; Animals; Charybdotoxin; Chromatography; Cysteine; Disulfides; Dose-Response Relationship, Drug; Electrophysiology; Hydrogen Bonding; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Lysine; Methionine; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis; Oocytes; Patch-Clamp Techniques; Peptides; Potassium Channels, Calcium-Activated; Protein Structure, Tertiary; Scorpion Venoms; Scorpions; Sequence Homology, Amino Acid; Sodium; Sulfoxides; Time Factors; Xenopus | 2005 |
Specific cross-linking of Lys233 and Cys235 in the mu opioid receptor by a reporter affinity label.
Topics: Arginine; Binding, Competitive; Cell Line; Cross-Linking Reagents; Cysteine; Fluorometry; Genes, Reporter; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Naphthalenes; Photoaffinity Labels; Protein Binding; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serine | 2005 |
Insights into the base catalysis exerted by the DD-transpeptidase from Streptomyces K15: a molecular dynamics study.
Topics: Binding Sites; Catalysis; Computer Simulation; Crystallization; Crystallography, X-Ray; Cysteine; Enzyme Stability; Lysine; Models, Chemical; Models, Molecular; Penicillin G; Penicillin-Binding Proteins; Quantum Theory; Serine; Serine-Type D-Ala-D-Ala Carboxypeptidase; Streptomyces; Thermodynamics | 2005 |
The conserved histidine 295 does not contribute to proton cotransport by the glutamate transporter EAAC1.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Biological Transport, Active; Cell Line; Conserved Sequence; Cysteine; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Patch-Clamp Techniques; Protons; Rats; Symporters; Transfection | 2005 |
Site-directed mutagenesis of active site residues of phosphite dehydrogenase.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cysteine; Deuterium Exchange Measurement; Diethyl Pyrocarbonate; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; Phosphites; Sequence Alignment | 2005 |
Caspase-8 sumoylation is associated with nuclear localization.
Topics: Amino Acid Sequence; Anisomycin; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Line, Tumor; Cell Nucleus; Cysteine; Cytoplasm; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Gene Library; Humans; Immunoprecipitation; Jurkat Cells; Lymphocytes; Lysine; Mass Spectrometry; Molecular Sequence Data; Neurons; Nucleic Acid Synthesis Inhibitors; Protein Structure, Tertiary; Subcellular Fractions; SUMO-1 Protein; Two-Hybrid System Techniques | 2005 |
Susceptibility of actin to modification by 4-hydroxy-2-nonenal.
Topics: Actins; Albumins; Aldehydes; Animals; Antibodies, Monoclonal; Blotting, Western; Cysteine; Ferric Compounds; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Histidine; Kidney; Kidney Neoplasms; Lysine; Male; Metallothionein; Nitrilotriacetic Acid; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Superoxide Dismutase | 2005 |
Amino acid residues associated with enzymatic activities of the isomerizing phycoviolobilin-lyase PecE/F.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Bacterial Proteins; Binding Sites; Cyanobacteria; Cysteine; Enzyme Activation; Histidine; Isomerism; Kinetics; Lyases; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phycobilins; Phycocyanin; Protein Subunits; Pyrroles; Sequence Deletion; Tetrapyrroles; Tryptophan | 2005 |
Proteomic analysis of redox- and ErbB2-dependent changes in mammary luminal epithelial cells using cysteine- and lysine-labelling two-dimensional difference gel electrophoresis.
Topics: Animals; Carbocyanines; Cell Line; Cysteine; Electrophoresis, Gel, Two-Dimensional; Epithelial Cells; Fluorescent Dyes; Gene Expression Regulation; Genes, erbB-2; Image Processing, Computer-Assisted; Lysine; Molecular Chaperones; Oxidation-Reduction; Oxidative Stress; Proteins; Sensitivity and Specificity; Sequence Analysis | 2005 |
Intermolecular contact between globular N-terminal fold and C-terminal domain of ApoA-I stabilizes its lipid-bound conformation: studies employing chemical cross-linking and mass spectrometry.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Chromatography, Liquid; Cross-Linking Reagents; Cysteine; Dimerization; Electrophoresis, Polyacrylamide Gel; Glycerylphosphorylcholine; Lipids; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutation; Oligonucleotides; Peptides; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Spectrometry, Mass, Electrospray Ionization; Succinimides; Trypsin; Urea | 2005 |
Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line; CHO Cells; Cricetinae; Cysteine; Down-Regulation; Endocytosis; Herpesvirus 8, Human; HLA-B7 Antigen; Humans; Lysine; Mutation; Protein Structure, Tertiary; Serine; Transduction, Genetic; Ubiquitin; Ubiquitin-Protein Ligases | 2005 |
Molecular modeling and site-directed mutagenesis of plant chloroplast monogalactosyldiacylglycerol synthase reveal critical residues for activity.
Topics: Amino Acid Sequence; Binding Sites; Cations; Chloroplasts; Chromatography; Crystallography, X-Ray; Cysteine; Detergents; Dimerization; Durapatite; Escherichia coli; Galactosyltransferases; Gene Expression Regulation, Plant; Genetic Vectors; Glycosyltransferases; Histidine; Hydrogen Bonding; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotides; Phylogeny; Point Mutation; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Spinacia oleracea | 2005 |
4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal.
Topics: Aldehydes; Butylamines; Cell Line; Cell Survival; Cysteine; Cysteine Proteinase Inhibitors; Histidine; Humans; Immunohistochemistry; Indicators and Reagents; Kinetics; Lysine; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Proteins; Schiff Bases; Spectrophotometry, Ultraviolet | 2005 |
Conformational changes of pore helix coupled to gating of TRPV5 by protons.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Calcium Channels; Cysteine; Hydrogen-Ion Concentration; Ion Channel Gating; Lysine; Molecular Sequence Data; Protein Conformation; Protons; Rabbits; Sequence Alignment | 2005 |
Erythrocyte spectrin's chimeric E2/E3 ubiquitin conjugating/ligating activity.
Topics: Blotting, Western; Cysteine; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Humans; Lysine; Protein Structure, Tertiary; Recombinant Fusion Proteins; Spectrin; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases | 2005 |
Switching DNA-binding specificity by unnatural amino acid substitution.
Topics: Amino Acid Substitution; Circular Dichroism; Cysteine; DNA-Binding Proteins; Hydrogen Bonding; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Operator Regions, Genetic; Repressor Proteins; Spectrometry, Fluorescence; Viral Proteins; Viral Regulatory and Accessory Proteins | 2005 |
Thymosin beta4 induces a conformational change in actin monomers.
Topics: Acrylamide; Actins; Adenosine Triphosphate; Animals; Calorimetry, Differential Scanning; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescence Resonance Energy Transfer; Hot Temperature; Kinetics; Lysine; Models, Molecular; Molecular Conformation; Nucleotides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Purines; Rabbits; Solvents; Spectrometry, Fluorescence; Temperature; Thymosin | 2006 |
Crystallization and preliminary X-ray diffraction studies of two myotoxic Lys49-phospholipases A2 complexed with alpha-tocopherol.
Topics: alpha-Tocopherol; Animals; Binding Sites; Bothrops; Crotalid Venoms; Crystallization; Cysteine; Group II Phospholipases A2; Group IV Phospholipases A2; Lysine; Phospholipases A; Phospholipases A2; Reptilian Proteins; Snake Venoms; X-Ray Diffraction | 2005 |
Relationships of Cysteine and Lysine residues with the substrate binding site of the mitochondrial ornithine/citrulline carrier: an inhibition kinetic approach combined with the analysis of the homology structural model.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Transport Systems, Basic; Animals; Binding Sites; Biological Transport; Citrulline; Cysteine; Lysine; Mutation; Ornithine; Protein Conformation; Pyridoxal Phosphate; Rats; Structural Homology, Protein; Sulfhydryl Reagents | 2005 |
Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis.
Topics: Binding Sites; Blotting, Western; Cloning, Molecular; Cysteine; DNA, Complementary; Escherichia coli; Glutathione Transferase; Humans; Lysine; Multienzyme Complexes; Plasmids; Polyubiquitin; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Time Factors; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases | 2005 |
Accelerated on-column lysine derivatization and cysteine methylation by imidazole reaction in a deuterated environment for enhanced product ion analysis.
Topics: Amino Acid Sequence; Cysteine; Deuterium; Erythropoietin; Humans; Imidazoles; Interferon alpha-2; Interferon-alpha; Lysine; Metalloendopeptidases; Methylation; Molecular Sequence Data; Molecular Structure; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin | 2006 |
Regulation of G protein-coupled receptor trafficking by inefficient plasma membrane expression: molecular basis of an evolved strategy.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Bridged Bicyclo Compounds, Heterocyclic; Buserelin; Cell Culture Techniques; Cell Membrane; Chlorocebus aethiops; COS Cells; Cysteine; Disulfides; Evolution, Molecular; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Humans; Indoles; Inositol Phosphates; Lysine; Mice; Molecular Sequence Data; Point Mutation; Protein Conformation; Protein Structure, Tertiary; Pyridines; Rats; Receptors, G-Protein-Coupled; Receptors, LHRH; Sequence Homology, Amino Acid; Species Specificity; Thermodynamics | 2006 |
Tethering functional ligands onto shell of ultrasound active polymeric microbubbles.
Topics: beta-Cyclodextrins; Cell Line, Tumor; Cell Proliferation; Chemical Phenomena; Chemistry, Physical; Chitosan; Cysteine; Humans; In Vitro Techniques; Ligands; Lysine; Microbubbles; Molecular Weight; Nanostructures; Particle Size; Polylysine; Polyvinyl Alcohol; Surface Properties | 2006 |
Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa.
Topics: Amidohydrolases; Binding Sites; Citrulline; Cobalt; Cysteine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Lysine; Mass Spectrometry; Models, Chemical; omega-N-Methylarginine; Protons; Pseudomonas aeruginosa; Spectrophotometry, Ultraviolet; Spectrum Analysis; Thiourea; X-Rays; Zinc | 2006 |
Roles of conserved basic amino acid residues and activation mechanism of the hyperthermophilic aspartate racemase at high temperature.
Topics: Amino Acid Isomerases; Arginine; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Kinetics; Lysine; Models, Molecular; Plasmids; Protein Conformation; Pyrococcus horikoshii; Static Electricity; Temperature | 2006 |
ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents.
Topics: Acid Sensing Ion Channels; Amino Acid Sequence; Animals; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; CHO Cells; Cricetinae; Cysteine; Extracellular Fluid; Lysine; Membrane Potentials; Membrane Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Oxidants; Oxidation-Reduction; Patch-Clamp Techniques; Protein Structure, Tertiary; Reducing Agents; Sodium Channels | 2006 |
Structure and dynamics of dark-state bovine rhodopsin revealed by chemical cross-linking and high-resolution mass spectrometry.
Topics: Amino Acid Sequence; Animals; Cattle; Chromatography, Liquid; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Lysine; Mass Spectrometry; Molecular Sequence Data; Protein Conformation; Rhodopsin; Spectroscopy, Fourier Transform Infrared; Succinimides | 2006 |
The Mycobacterium tuberculosis LipB enzyme functions as a cysteine/lysine dyad acyltransferase.
Topics: Acyltransferases; Cysteine; Decanoic Acids; Lysine; Mass Spectrometry; Models, Molecular; Mycobacterium tuberculosis | 2006 |
Specific vectorial immobilization of oligonucleotide-modified yeast cytochrome C on carbon nanotubes.
Topics: Adsorption; Binding Sites; Biosensing Techniques; Cysteine; Cytochromes c; Detergents; Electrochemistry; Enzymes; Lysine; Microscopy, Atomic Force; Microscopy, Fluorescence; Nanotubes, Carbon; Oligonucleotides; Saccharomyces cerevisiae; Spectrophotometry | 2006 |
Identification of cysteinylation of a free cysteine in the Fab region of a recombinant monoclonal IgG1 antibody using Lys-C limited proteolysis coupled with LC/MS analysis.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Cysteine; Gas Chromatography-Mass Spectrometry; Glycosylation; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunoglobulin G; Lysine; Molecular Sequence Data; Molecular Weight; Peptide Hydrolases; Peptide Mapping; Protein Isoforms; Receptor-CD3 Complex, Antigen, T-Cell; Recombinant Proteins | 2006 |
Conformation and microenvironment of the active site of a low molecular weight 1,4-beta-D-glucan glucanohydrolase from an alkalothermophilic Thermomonospora sp.: involvement of lysine and cysteine residues.
Topics: Actinomycetales; Binding Sites; Carboxymethylcellulose Sodium; Circular Dichroism; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Glucan 1,4-beta-Glucosidase; Hydroxymercuribenzoates; Kinetics; Lysine; Molecular Sequence Data; Molecular Weight; Protein Conformation; Sequence Alignment; Substrate Specificity; Trinitrobenzenesulfonic Acid | 2006 |
Identification of the cadaverine recognition site on the cadaverine-lysine antiporter CadB.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Antiporters; Arginine; Binding Sites; Cadaverine; Cysteine; Cytoplasm; Escherichia coli; Escherichia coli Proteins; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation | 2006 |
The metal-binding sites of the zinc-transporting P-type ATPase of Escherichia coli. Lys693 and Asp714 in the seventh and eighth transmembrane segments of ZntA contribute to the coupling of metal binding and ATPase activity.
Topics: Adenosine Triphosphatases; Asparagine; Binding Sites; Copper; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Lysine; Metals; Phosphorylation; Protein Structure, Tertiary; Substrate Specificity; Zinc | 2006 |
DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antineoplastic Combined Chemotherapy Protocols; Arginine; Asparagine; Aspartic Acid; Carcinoma, Squamous Cell; Cisplatin; Cysteine; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Endonucleases; Female; Gene Frequency; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Lysine; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Survival Analysis; Treatment Outcome; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein | 2006 |
Toll-like receptor 4 region Glu24-Lys47 is a site for MD-2 binding: importance of CYS29 and CYS40.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cysteine; Glutamic Acid; Humans; Lymphocyte Antigen 96; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Signal Transduction; Toll-Like Receptor 4 | 2006 |
Mass spectrometry-based glycoproteomic approach involving lysine derivatization for structural characterization of recombinant human erythropoietin.
Topics: Amino Acid Sequence; Cysteine; Deuterium; Erythropoietin; Glycoproteins; Glycosylation; Humans; Lysine; Molecular Sequence Data; Peptide Fragments; Polysaccharides; Proteomics; Recombinant Proteins; Trypsin | 2006 |
Specializations of a G-protein-coupled receptor that appear to aid with detection of frequency-modulated signals from its ligand.
Topics: Amino Acid Sequence; Animals; Buserelin; Chlorocebus aethiops; Conserved Sequence; COS Cells; Cysteine; Dogs; Humans; Inositol Phosphates; Lysine; Mice; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutant Proteins; Primates; Protein Binding; Radioligand Assay; Rats; Receptors, G-Protein-Coupled; Receptors, LHRH; Species Specificity; Transfection | 2007 |
Identification of catalytic cysteine, histidine, and lysine residues in Escherichia coli homoserine transsuccinylase.
Topics: Catalysis; Cysteine; Escherichia coli; Histidine; Homoserine O-Succinyltransferase; Hydrogen-Ion Concentration; Iodoacetamide; Lysine; Models, Molecular; Mutagenesis, Site-Directed | 2007 |
Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad.
Topics: Amidohydrolases; Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Glutamic Acid; Helicobacter pylori; Ligands; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Sequence Homology, Amino Acid | 2007 |
Construction of Lactobacillus plantarum strain with enhanced L-lysine yield.
Topics: Amino Acid Sequence; Aspartate Kinase; Aspartate-Semialdehyde Dehydrogenase; Base Sequence; Cysteine; Dihydrodipicolinate Reductase; DNA, Bacterial; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Hydro-Lyases; Lactobacillus plantarum; Lysine; Mutation; Protein Synthesis Inhibitors; Recombination, Genetic | 2007 |
Chemical modification of mono-cysteine mutants allows a more global look at conformations of the epsilon subunit of the ATP synthase from Escherichia coli.
Topics: Adenosine Triphosphate; Bacterial Proton-Translocating ATPases; Cysteine; Escherichia coli Proteins; Hydrolysis; Lysine; Maleimides; Models, Molecular; Mutation; Protein Structure, Secondary; Protein Subunits | 2007 |
Lysine N(zeta)-decarboxylation in the BlaR1 protein from Staphylococcus aureus at the root of its function as an antibiotic sensor.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Carrier Proteins; Crystallography, X-Ray; Cysteine; Decarboxylation; Kinetics; Lysine; Models, Molecular; Mutation; Penicillin-Binding Proteins; Protein Structure, Tertiary; Staphylococcus aureus | 2007 |
Structural Insight into concerted inhibition of alpha 2 beta 2-type aspartate kinase from Corynebacterium glutamicum.
Topics: Amino Acid Sequence; Aspartate Kinase; Binding Sites; Corynebacterium glutamicum; Crystallography, X-Ray; Cysteine; Dimerization; Drug Resistance, Microbial; Feedback, Physiological; Ligands; Lysine; Molecular Sequence Data; Molecular Weight; Mutant Proteins; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Threonine | 2007 |
The site-specific installation of methyl-lysine analogs into recombinant histones.
Topics: Animals; Cysteine; Histones; Lysine; Methylation; Models, Molecular; Nucleosomes; Recombinant Proteins; Xenopus Proteins | 2007 |
Quantification of chemical peptide reactivity for screening contact allergens: a classification tree model approach.
Topics: Allergens; Animals; Cysteine; Data Interpretation, Statistical; Dermatitis, Allergic Contact; Female; Forecasting; Glutathione; Lymph Nodes; Lysine; Mice; Mice, Inbred CBA; Models, Statistical; Peptides | 2007 |
Effects of a mutation in the TM2-TM3 linker region of the glycine receptor alpha1 subunit on gating and allosteric modulation.
Topics: Alanine; Allosteric Regulation; Amino Acid Sequence; Anesthetics, Inhalation; Animals; Binding Sites; Cysteine; Ethanol; Female; In Vitro Techniques; Ion Channel Gating; Lysine; Molecular Sequence Data; Mutation; Oocytes; Proline; Protein Structure, Tertiary; Protein Subunits; Receptors, Glycine; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Sequence Alignment; Signal Transduction; Xenopus laevis | 2007 |
Characterization of transport systems for cysteine, lysine, alanine, and leucine in wool follicles of sheep.
Topics: Alanine; Amino Acid Transport Systems; Amino Acids; Animals; Biological Transport; Cysteine; Hair Follicle; Kinetics; Leucine; Lysine; Sheep; Tissue Culture Techniques; Wool | 2007 |
Chemical introduction of reactive thiols into a viral nanoscaffold: a method that avoids virus aggregation.
Topics: Comovirus; Cysteine; Electrophoresis, Agar Gel; Fluorescent Dyes; Lysine; Models, Chemical; Models, Molecular; Mutation; Nanoparticles; Nanotechnology; Sepharose; Solvents; Sulfhydryl Compounds; Ultracentrifugation; Viruses | 2007 |
Analysis of modified apolipoprotein B-100 structures formed in oxidized low-density lipoprotein using LC-MS/MS.
Topics: Acrolein; Aldehydes; Amino Acid Sequence; Apolipoprotein B-100; Chloroform; Chromatography, Liquid; Copper Sulfate; Cysteine; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Kynurenine; Lipoproteins, LDL; Lysine; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Polyvinyls; Tandem Mass Spectrometry; Trypsin; Tryptophan | 2007 |
A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.
Topics: Amino Acid Sequence; Cysteine; Humans; Lysine; Membrane Transport Proteins; Mercaptoethanol; Molecular Sequence Data; Peroxins; Peroxisome-Targeting Signal 1 Receptor; Plasmids; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Ubiquitin; Ubiquitin-Conjugating Enzymes | 2007 |
In vivo crosslinking methods for analyzing the assembly and architecture of chemoreceptor arrays.
Topics: Archaeal Proteins; Bacteria; Bacterial Proteins; Biochemistry; Chemoreceptor Cells; Cross-Linking Reagents; Cysteine; Cytoplasm; Dimerization; Disulfides; Escherichia coli Proteins; Lysine; Models, Chemical; Models, Genetic; Molecular Conformation; Mutation; Protein Binding | 2007 |
Stimulation and oxidative catalytic inactivation of thermolysin by copper.Cys-Gly-His-Lys.
Topics: Amino Acid Motifs; Amino Acid Sequence; Catalysis; Copper; Cysteine; Electrochemistry; Enzyme Activation; Glycine; Histidine; Lysine; Macromolecular Substances; Molecular Sequence Data; Molecular Structure; Oligopeptides; Organometallic Compounds; Oxidation-Reduction; Sequence Alignment; Thermolysin | 2007 |
Interaction between lysine 102 and aspartate 338 in the insect amino acid cotransporter KAAT1.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acid Transport Systems, Neutral; Animals; Aspartic Acid; Binding Sites; Biological Transport; Cross-Linking Reagents; Cysteine; Dithiothreitol; Female; Insect Proteins; Kinetics; Lepidoptera; Lysine; Models, Molecular; Molecular Sequence Data; Oocytes; Phenanthrolines; Potassium; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sodium; Tryptophan; Xenopus laevis | 2007 |
Urinary LTE4 is higher after nasal provocation test with L-ASA in bronchial than in only nasal responders.
Topics: Adult; Aspirin; Asthma; Bronchial Hyperreactivity; Cysteine; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Leukotrienes; Lysine; Male; Middle Aged; Nasal Cavity; Nasal Provocation Tests; Rhinometry, Acoustic | 2007 |
Residue-specific adduction of tubulin by 4-hydroxynonenal and 4-oxononenal causes cross-linking and inhibits polymerization.
Topics: Aldehydes; Animals; Brain; Cattle; Cross-Linking Reagents; Cysteine; Electrophoresis, Gel, Two-Dimensional; Lysine; Mass Spectrometry; Oxidative Stress; Polymers; Tubulin | 2007 |
Steric interactions stabilize the signaling state of the LOV2 domain of phototropin 1.
Topics: Arginine; Circular Dichroism; Cryptochromes; Cysteine; Directed Molecular Evolution; Electric Conductivity; Escherichia coli; Flavoproteins; Isoleucine; Light; Lysine; Mutagenesis, Site-Directed; Oxygen; Photochemistry; Plant Proteins; Protein Structure, Tertiary; Signal Transduction; Spectrometry, Fluorescence; Stereoisomerism; Valine | 2007 |
Catalytic mechanism of penicillin-binding protein 5 of Escherichia coli.
Topics: Acylation; Amino Acid Substitution; beta-Lactamases; Binding Sites; Catalysis; Cell Wall; Cysteine; Escherichia coli; Escherichia coli Proteins; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Penicillin-Binding Proteins; Peptidoglycan; Protein Binding; Proton Pumps | 2007 |
Biochemical characterization of a novel beta-1--3, 1--4 glucan 4-glucanohydrolase from Thermomonospora sp. having a single active site for lichenan and xylan.
Topics: Actinomycetales; Affinity Labels; Binding Sites; Circular Dichroism; Cysteine; Dithionitrobenzoic Acid; Glucan 1,4-beta-Glucosidase; Glucans; Hydrolysis; Kinetics; Lysine; o-Phthalaldehyde; Protein Binding; Substrate Specificity; Trinitrobenzenesulfonic Acid; Xylan Endo-1,3-beta-Xylosidase; Xylans | 2007 |
Perturbations in factor XIII resulting from activation and inhibition examined by solution based methods and detected by MALDI-TOF MS.
Topics: Acetylation; Alkylation; Calcium; Catalysis; Cations, Divalent; Computer Simulation; Cysteine; Deuterium Exchange Measurement; Enzyme Activation; Enzyme Inhibitors; Factor XIII; Factor XIIIa; Glutamine; Humans; Iodoacetamide; Lysine; Models, Molecular; Peptides; Recombinant Fusion Proteins; Solutions; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thrombin | 2007 |
Specificity of acyl transfer from 2-mercaptobenzamide thioesters to the HIV-1 nucleocapsid protein.
Topics: Amino Acid Sequence; Cysteine; Esters; HIV-1; Lysine; Models, Molecular; Nucleocapsid Proteins | 2007 |
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.
Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Biomarkers; Cell Differentiation; Citric Acid Cycle; Cysteine; Diabetes Complications; Diabetes Mellitus, Type 2; Fibroblasts; Fumarates; Humans; Insulin Resistance; Lysine; Mice; Mitochondria; Obesity; Protein Processing, Post-Translational; Risk Factors; Stress, Physiological; Succinic Acid; Sulfhydryl Compounds | 2007 |
Synthesis and characterization of styrene oxide adducts with cysteine, histidine, and lysine in human globin.
Topics: Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Environmental Monitoring; Environmental Pollutants; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Globins; Histidine; Humans; Lysine; Magnetic Resonance Spectroscopy; Stereoisomerism | 2007 |
Photoaddition of fluphenazine to nucleophiles in peptides and proteins. Possible cause of immune side effects.
Topics: Agranulocytosis; Amino Acids; Antipsychotic Agents; Carboxylic Acids; Cysteine; Fluphenazine; Hydrogen-Ion Concentration; Lysine; Peptides; Photolysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine; Ultraviolet Rays | 2007 |
An estimate of the methionine requirement and its variability in growing pigs using the indicator amino acid oxidation technique.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Carbon Dioxide; Carbon Radioisotopes; Cross-Over Studies; Cysteine; Dose-Response Relationship, Drug; Female; Linear Models; Lysine; Methionine; Nutritional Requirements; Oxidation-Reduction; Oxygen Consumption; Phenylalanine; Random Allocation; Swine | 2008 |
Effect of a single AGE modification on the structure and chaperone activity of human alphaB-crystallin.
Topics: alpha-Crystallin B Chain; Circular Dichroism; Cysteine; Electrophoresis, Gel, Two-Dimensional; Fluorescence; Glycation End Products, Advanced; Humans; Lysine; Molecular Chaperones; Molecular Structure; Protein Binding; Pyridinium Compounds; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tandem Mass Spectrometry; Tryptophan | 2007 |
CLC Cl /H+ transporters constrained by covalent cross-linking.
Topics: Animals; Biological Transport; Chloride Channels; Cross-Linking Reagents; Cysteine; Cystine; Disulfides; Escherichia coli; Hydrogen-Ion Concentration; Ions; Kinetics; Lipid Bilayers; Lysine; Mice; Molecular Conformation; Mutation; Oxidants; Oxygen; Protein Structure, Secondary | 2007 |
Interaction of the Lys(3614)-Asn(3643) calmodulin-binding domain with the Cys(4114)-Asn(4142) region of the type 1 ryanodine receptor is involved in the mechanism of Ca2+/agonist-induced channel activation.
Topics: Animals; Asparagine; Calcium; Calcium Channels; Calmodulin; Cysteine; Lysine; Molecular Weight; Protein Binding; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum | 2008 |
ATP-driven reduction by dark-operative protochlorophyllide oxidoreductase from Chlorobium tepidum mechanistically resembles nitrogenase catalysis.
Topics: Adenosine Triphosphate; Catalysis; Chlorobium; Cysteine; Dithionite; Electrons; Escherichia coli; Heme; Kinetics; Leucine; Light; Lysine; Nitrogenase; Oxidoreductases; Protochlorophyllide | 2008 |
The specificities of Kaposi's sarcoma-associated herpesvirus-encoded E3 ubiquitin ligases are determined by the positions of lysine or cysteine residues within the intracytoplasmic domains of their targets.
Topics: Cysteine; Herpesvirus 8, Human; HLA-B7 Antigen; Humans; Lysine; Membrane Proteins; Models, Biological; Protein Structure, Tertiary; Substrate Specificity; Ubiquitin-Protein Ligases; Viral Proteins | 2008 |
Albumin is the main nucleophilic target of human plasma: a protective role against pro-atherogenic electrophilic reactive carbonyl species?
Topics: Adult; Aldehydes; Atherosclerosis; Cysteine; Humans; Lysine; Peptides; Protective Agents; Serum Albumin | 2008 |
Controlling orientations of immobilized oligopeptides using N-terminal cysteine labels.
Topics: Aldehydes; Biochemistry; Crystallization; Cysteine; Electrochemistry; Lysine; Models, Chemical; Oligopeptides; Peptides; Protein Conformation; Protein Structure, Tertiary; Thiazolidines; Trypsin | 2008 |
Model studies on protein glycation: influence of cysteine on the reactivity of arginine and lysine residues toward glyoxal.
Topics: Arginine; Chromatography, High Pressure Liquid; Cysteine; Glycosylation; Glyoxal; Kinetics; Lysine; Mass Spectrometry; Models, Molecular | 2008 |
Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore.
Topics: Animals; Arginine; Cell Line; Chlorides; Cricetinae; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Lysine; Membrane Potentials; Mutagenesis, Site-Directed; Mutation; Permeability; Platinum Compounds; Protein Conformation; Protein Structure, Tertiary; Static Electricity; Structure-Activity Relationship; Transfection | 2008 |
In situ synthesis of lipopeptides as versatile receptors for the specific binding of nanoparticles and liposomes to solid-supported membranes.
Topics: Cysteine; Diffusion; Lipid Bilayers; Liposomes; Lysine; Maleimides; Micelles; Microscopy, Confocal; Models, Chemical; Nanoparticles; Nanotechnology; Peptides; Phospholipids; Static Electricity; Water | 2008 |
Design of (Gd-DO3A)n-polydiamidopropanoyl-peptide nucleic acid-D(Cys-Ser-Lys-Cys) magnetic resonance contrast agents.
Topics: Anthracenes; Base Sequence; Chelating Agents; Computer Simulation; Cysteine; Gadolinium; Gadolinium DTPA; Lysine; Magnetic Resonance Imaging; Models, Molecular; Molecular Conformation; Oligonucleotides; Oligopeptides; Peptide Nucleic Acids; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2008 |
Structural basis for a distinct catalytic mechanism in Trypanosoma brucei tryparedoxin peroxidase.
Topics: Amino Acid Sequence; Animals; Cysteine; DNA Mutational Analysis; Lysine; Magnetic Resonance Spectroscopy; Models, Biological; Molecular Sequence Data; Oxygen; Peroxidases; Protein Binding; Protein Conformation; Protozoan Proteins; Sequence Homology, Amino Acid; Thioredoxins; Trypanosoma brucei brucei | 2008 |
Antiglycative and anti-VEGF effects of s-ethyl cysteine and s-propyl cysteine in kidney of diabetic mice.
Topics: Albuminuria; Animals; Arginine; Blood Glucose; Creatinine; Cysteine; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Kidney; Lysine; Male; Mice; Mice, Inbred BALB C; Organ Size; Vascular Endothelial Growth Factor A | 2008 |
Preferential selection of Cys-constrained peptides from a random phage-displayed library by anti-glucitollysine antibodies.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cattle; Cloning, Molecular; Cysteine; Disulfides; Epitopes; Escherichia coli; Lysine; Molecular Sequence Data; Peptide Library; Peptides; Serum Albumin, Bovine; Sorbitol | 2008 |
Identification of four novel types of in vitro protein modifications.
Topics: Algorithms; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Chromatography, High Pressure Liquid; Cysteine; Glutamic Acid; Glycerol; Lysine; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Protein Processing, Post-Translational; Proteins; Reproducibility of Results; Sequence Alignment; Serum Albumin, Bovine | 2008 |
Tuning a three-component reaction for trapping kinase substrate complexes.
Topics: Adenosine; Cross-Linking Reagents; Cysteine; Fluorescent Dyes; HeLa Cells; Humans; Lysine; Models, Chemical; Molecular Conformation; Peptides; Phosphorylation; Phosphotransferases; Protein Structure, Tertiary; Proteins; Thiophenes | 2008 |
Development of dual-acting prodrugs for circumventing multidrug resistance.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cathepsin B; Chemistry, Pharmaceutical; Cysteine; Doxorubicin; Drug Design; Drug Resistance, Multiple; Humans; Lysine; Peptides; Phenylalanine; Prodrugs; Serum Albumin | 2009 |
An approach to characterizing single-subunit mutations in multimeric prepores and pores of anthrax protective antigen.
Topics: Alanine; Amino Acid Sequence; Animals; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; CHO Cells; Cricetinae; Cricetulus; Cysteine; Electrophysiology; Escherichia coli; Hydrogen-Ion Concentration; Lipid Bilayers; Lysine; Membrane Potentials; Mutation; Phenylalanine; Potassium; Protein Multimerization | 2009 |
Covalent modification of lysine residues by allyl isothiocyanate in physiological conditions: plausible transformation of isothiocyanate from thiol to amine.
Topics: Amines; Cysteine; Isothiocyanates; Lysine; Models, Chemical; Serum Albumin, Bovine; Sulfhydryl Compounds | 2009 |
Protein modification by acrolein: formation and stability of cysteine adducts.
Topics: Acrolein; Amino Acid Sequence; Animals; Cattle; Cysteine; Histidine; Hydrogen-Ion Concentration; Insulin; Lysine; Peptides; Schiff Bases; Spectrometry, Mass, Electrospray Ionization | 2009 |
Synthesis of a cross-linked branched polymer network in the interior of a protein cage.
Topics: Amines; Biomimetics; Cross-Linking Reagents; Cysteine; Heat-Shock Proteins; Lysine; Macromolecular Substances; Mass Spectrometry; Methanococcus; Models, Molecular; Molecular Structure; Polymers; Proteins; Temperature | 2009 |
Domain interplay mediated by an essential disulfide linkage is critical for the activity and secretion of the metastasis-promoting enzyme autotaxin.
Topics: Amino Acid Sequence; Animals; Biocatalysis; Cell Line; Cysteine; Disulfides; Dithiothreitol; Endopeptidases; Enzyme Activation; Humans; Lysine; Molecular Sequence Data; Neoplasm Metastasis; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; Pyrophosphatases; Rats; Structure-Activity Relationship | 2009 |
Functional ubiquitin conjugates with lysine-epsilon-amino-specific linkage by thioether ligation of cysteinyl-ubiquitin peptide building blocks.
Topics: Acetylation; Amines; Amino Acid Sequence; Circular Dichroism; Cysteine; Drug Design; Isomerism; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Protein Conformation; Substrate Specificity; Sulfides; Ubiquitin; Ubiquitination | 2009 |
Relevance of fatty acid covalently bound to Escherichia coli alpha-hemolysin and membrane microdomains in the oligomerization process.
Topics: Animals; Cholesterol; Cysteine; Erythrocyte Membrane; Escherichia coli; Escherichia coli Proteins; Fatty Acids; Fluorescence Resonance Energy Transfer; Hemolysin Proteins; Lysine; Membrane Microdomains; Models, Biological; Protein Binding; Protein Interaction Mapping; Protein Structure, Tertiary; Sheep | 2009 |
Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity.
Topics: Acetylation; Animals; Cell Cycle Proteins; Cell Line; Cell Survival; Cysteine; Forkhead Transcription Factors; Humans; Lysine; Mice; Mutation; Oxidation-Reduction; p300-CBP Transcription Factors; Peroxides; Reactive Oxygen Species; Signal Transduction; Thioredoxins; Transcription Factors | 2009 |
Extension arm facilitated pegylation of alphaalpha-hemoglobin with modifications targeted exclusively to amino groups: functional and structural advantages of free Cys-93(beta) in the PEG-Hb adduct.
Topics: Cross-Linking Reagents; Cysteine; Drug Design; Hemoglobins; Humans; Lysine; Molecular Structure; Oxygen; Oxyhemoglobins; Polyethylene Glycols; Protein Engineering | 2009 |
Non-antibiotic selection systems for soybean somatic embryos: the lysine analog aminoethyl-cysteine as a selection agent.
Topics: Culture Media; Cysteine; DNA, Plant; Genetic Engineering; Glycine max; Herbicides; Hydro-Lyases; Lysine; Plants, Genetically Modified | 2009 |
Identification of furan metabolites derived from cysteine-cis-2-butene-1,4-dial-lysine cross-links.
Topics: Aldehydes; Animals; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; Cytochrome P-450 Enzyme System; Furans; Lysine; Rats; Tandem Mass Spectrometry | 2010 |
The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.
Topics: Arginine; Cloning, Molecular; Cysteine; Dimerization; DNA, Complementary; Endopeptidases; Humans; Lysine; Mass Spectrometry; Mutation; Polyubiquitin; Time Factors; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitination | 2010 |
In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification.
Topics: Amino Acid Motifs; Chromatography, Liquid; Cysteine; HeLa Cells; Humans; Lysine; Mass Spectrometry; Peptides; Protein Processing, Post-Translational; Proteins; Proteome; Proteomics; Small Ubiquitin-Related Modifier Proteins; Trypsin; Ubiquitin | 2010 |
Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.
Topics: Animals; Corpus Striatum; Cysteine; Glutamine; GTP-Binding Proteins; Humans; Huntington Disease; Lysine; Mice; Mice, Knockout; Mutation; Small Ubiquitin-Related Modifier Proteins; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases | 2010 |
Characterization of apical and basal thiol-disulfide redox regulation in human colonic epithelial cells.
Topics: Biological Transport; Caco-2 Cells; Cell Membrane; Colon; Cysteine; Cystine; Disulfides; Down-Regulation; Epithelial Cells; Extracellular Fluid; Glutathione; Humans; Intracellular Membranes; Lysine; Osmolar Concentration; Oxidation-Reduction; Sodium; Sulfhydryl Compounds; Time Factors | 2010 |
Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation.
Topics: Acetylation; Alkylation; Animals; Aziridines; Binding Sites; Biomimetic Materials; Cysteine; Histones; Lysine; Peptides; Proteins; Substrate Specificity | 2010 |
Oxidative stress, Helicobacter pylori, and OGG1 Ser326Cys, XPC Lys939Gln, and XPD Lys751Gln polymorphisms in a Turkish population with colorectal carcinoma.
Topics: Adult; Aged; Amino Acid Substitution; Colorectal Neoplasms; Cysteine; DNA Glycosylases; DNA-Binding Proteins; Genetics, Population; Glutamine; Helicobacter Infections; Helicobacter pylori; Humans; Lysine; Middle Aged; Mutation, Missense; Oxidative Stress; Polymorphism, Single Nucleotide; Serine; Turkey; Xeroderma Pigmentosum Group D Protein | 2010 |
Rbx1 flexible linker facilitates cullin-RING ligase function before neddylation and after deneddylation.
Topics: Allosteric Regulation; Amino Acid Substitution; Carrier Proteins; Computer Simulation; Cullin Proteins; Cysteine; Lysine; Models, Biological; Models, Molecular; Mutant Proteins; Mutation; Protein Structure, Secondary; Substrate Specificity; Ubiquitin | 2010 |
Photophysics and photochemistry of the UV filter kynurenine covalently attached to amino acids and to a model protein.
Topics: Amino Acids; Animals; Chickens; Cysteine; Glutathione; Histidine; Humans; Kynurenine; Lasers; Light; Lysine; Molecular Structure; Muramidase; Peptides; Photochemistry; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Ultraviolet Rays | 2010 |
Chemical basis for the extreme skin sensitization potency of (E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one.
Topics: Animals; Cysteine; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Irritants; Kinetics; Lysine; Mice; Oxazolone; Peptides; Skin; Sulfhydryl Compounds | 2010 |
Posttranslational modification and regulation of glutamate-cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenal.
Topics: Aldehydes; Animals; Cysteine; Cysteine Proteinase Inhibitors; Glutamate-Cysteine Ligase; Humans; Lipid Peroxidation; Lysine; Mass Spectrometry; Metabolic Detoxication, Phase I; Mice; Oxidative Stress; Protein Processing, Post-Translational; Protein Subunits; Stereoisomerism; Tumor Cells, Cultured | 2011 |
Characterization of metal-labelled peptides by matrix-assisted laser desorption/ionization mass spectrometry and tandem mass spectrometry.
Topics: Animals; Cattle; Chelating Agents; Cysteine; Heterocyclic Compounds, 1-Ring; Lysine; Metals, Rare Earth; Peptide Fragments; Peptides; Serum Albumin, Bovine; Signal Processing, Computer-Assisted; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2010 |
Water-driven ligations using cyclic amino squarates: a class of useful SN1-like reactions.
Topics: Cyclization; Cyclobutanes; Cysteine; Lysine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Water | 2011 |
Quantitative reactivity profiling predicts functional cysteines in proteomes.
Topics: Animals; Biocatalysis; Cell Line, Tumor; Conserved Sequence; Cysteine; Humans; Hydrolases; Iron-Sulfur Proteins; Liver; Mice; Myocardium; Nuclear Proteins; Oxidation-Reduction; Protein Engineering; Protein Hydrolysates; Protein-Arginine N-Methyltransferases; Proteins; Proteome; Proteomics; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2010 |
Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids.
Topics: Animals; Cell Line; Chlorocebus aethiops; COS Cells; Cysteine; Endoplasmic Reticulum; Humans; Hydrogen-Ion Concentration; Immunoglobulin kappa-Chains; Lysine; Mice; NIH 3T3 Cells; Protein Structure, Tertiary; Protein Unfolding; Saccharomyces cerevisiae Proteins; Serine; Sodium Hydroxide; Substrate Specificity; Threonine; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2010 |
Vulnerability of the cysteine-less proton-coupled folate transporter (PCFT-SLC46A1) to mutational stress associated with the substituted cysteine accessibility method.
Topics: Amino Acid Sequence; Amino Acid Substitution; Biological Transport; Blotting, Western; Cysteine; HeLa Cells; Humans; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Stability; Proton-Coupled Folate Transporter | 2011 |
Identification of amino acid residues responsible for the release of free drug from an antibody-drug conjugate utilizing lysine-succinimidyl ester chemistry.
Topics: Antibodies, Monoclonal; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cysteine; Drug Compounding; Drug Stability; Esters; Hydrolysis; Immunotoxins; Kinetics; Lysine; Models, Chemical; Peptide Mapping; Solubility; Succinimides; Tandem Mass Spectrometry; Technology, Pharmaceutical; Tyrosine; Umbelliferones | 2011 |
Detection and function of an intramolecular disulfide bond in the pH-responsive CadC of Escherichia coli.
Topics: Amino Acid Substitution; Cysteine; Disulfides; Escherichia coli; Escherichia coli Proteins; Hydrogen-Ion Concentration; Lysine; Models, Biological; Models, Chemical; Mutagenesis, Site-Directed; Mutant Proteins; Trans-Activators | 2011 |
Isobaric peptide termini labeling utilizing site-specific N-terminal succinylation.
Topics: Algorithms; Apoptosis; Chromatography, High Pressure Liquid; Cysteine; HeLa Cells; Humans; Lysine; Peptides; Proteome; Succinic Anhydrides; Tandem Mass Spectrometry | 2011 |
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids.
Topics: Amino Acid Sequence; Carrier Proteins; Catalytic Domain; Cysteine; Humans; Lysine; Molecular Sequence Data; Mutant Chimeric Proteins; Protein Binding; Protein Structure, Tertiary; Sequence Alignment; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases | 2011 |
N-methyl-phenacyloxycarbamidomethyl (Pocam) group: a novel thiol protecting group for solid-phase peptide synthesis and peptide condensation reactions.
Topics: Animals; Azides; Chemistry, Pharmaceutical; Chromatography, Reverse-Phase; Cysteine; Humans; Indicators and Reagents; Lysine; Peptides; Solid-Phase Synthesis Techniques; Zinc | 2011 |
The incorporation of lysine into the peroxidase peptide reactivity assay for skin sensitization assessments.
Topics: Allergens; Animal Use Alternatives; Chromatography, High Pressure Liquid; Cysteine; Dermatitis, Allergic Contact; Haptens; Humans; Lysine; Peptides; Peroxidase; Risk Assessment; Skin; Skin Tests; Tandem Mass Spectrometry; Toxicity Tests | 2011 |
The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.
Topics: Amino Acid Substitution; Apoenzymes; Base Sequence; Catalytic Domain; Cysteine; Deuterium Exchange Measurement; DNA, Fungal; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Saccharopine Dehydrogenases; Sulfhydryl Compounds | 2011 |
Cross-linking of wheat gluten proteins during production of hard pretzels.
Topics: Alanine; Chromatography, Ion Exchange; Cross-Linking Reagents; Cysteine; Cystine; Food Handling; Food Technology; Glutens; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Lysinoalanine; Maillard Reaction; Reducing Agents; Sodium Dodecyl Sulfate; Sodium Hydroxide; Sulfides; Triticum | 2012 |
The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states.
Topics: Animals; Base Sequence; Cell Line; Cysteine; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Lysine; Methylation; Molecular Sequence Data; Mutation; Polycomb Repressive Complex 2; Sequence Analysis, DNA; Substrate Specificity; Transcription Factors | 2011 |
Quantitative assessment of protein interaction with methyl-lysine analogues by hybrid computational and experimental approaches.
Topics: Binding Sites; Computer Simulation; Cysteine; Escherichia coli; Ligands; Lysine; Methylation; Models, Molecular; Molecular Mimicry; Peptides; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Thermodynamics | 2012 |
Cysteine-dependent ubiquitination of Pex18p is linked to cargo translocation across the peroxisomal membrane.
Topics: Cysteine; Immunoblotting; Intracellular Membranes; Lysine; Membrane Transport Proteins; Mutation; Peroxisomal Targeting Signal 2 Receptor; Peroxisome-Targeting Signal 1 Receptor; Peroxisomes; Protein Transport; Receptors, Cytoplasmic and Nuclear; Saccharomyces cerevisiae Proteins; Ubiquitination | 2011 |
The basic property of Lys385 is important for potentiation of the human α1 glycine receptor by ethanol.
Topics: Amino Acid Substitution; Cell Membrane; Chemical Phenomena; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiological Phenomena; Ethanol; Ethyl Methanesulfonate; Glycine; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Humans; Ion Channel Gating; Lysine; Models, Molecular; Neurotransmitter Agents; Patch-Clamp Techniques; Propofol; Protein Interaction Domains and Motifs; Receptors, Glycine; Recombinant Fusion Proteins; Static Electricity; Surface Properties; Transfection | 2012 |
Investigation of the reactivity between a ruthenium hexacationic prism and biological ligands.
Topics: Amino Acids; Antineoplastic Agents; Arginine; Ascorbic Acid; Cymenes; Cysteine; Disulfides; Glucose; Glutathione; Ligands; Lysine; Magnetic Resonance Spectroscopy; Methionine; Monoterpenes; Organomercury Compounds; Oxidation-Reduction; Ruthenium; Solutions; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds | 2012 |
Characterization of oxidation products from 1-palmitoyl-2-linoleoyl-sn-glycerophosphatidylcholine in aqueous solutions and their reactions with cysteine, histidine and lysine residues.
Topics: Amino Acid Sequence; Cysteine; Histidine; Lipid Peroxidation; Lysine; Molecular Sequence Data; Oxidation-Reduction; Peptides; Phosphatidylcholines | 2012 |
Production of recombinant oxytocin through sulfitolysis of inteincontaining fusion protein.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; Humans; Hydrogen-Ion Concentration; Inclusion Bodies; Inteins; Lysine; Molecular Sequence Data; Oxytocin; Protein Refolding; Recombinant Fusion Proteins; Solubility; Trypsin; Urea | 2012 |
Urinary AASA excretion is elevated in patients with molybdenum cofactor deficiency and isolated sulphite oxidase deficiency.
Topics: 2-Aminoadipic Acid; Adolescent; Amino Acid Metabolism, Inborn Errors; Child; Coenzymes; Cysteine; Humans; Infant, Newborn; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Metabolic Networks and Pathways; Metal Metabolism, Inborn Errors; Metalloproteins; Models, Biological; Molybdenum Cofactors; Molybdoferredoxin; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Sulfite Oxidase; Sulfites | 2012 |
Mass spectrometry-based absolute protein quantification: PSAQ™ strategy makes use of "noncanonical" proteotypic peptides.
Topics: Amino Acid Motifs; Arginine; Chromatography, Liquid; Cysteine; Humans; Isotope Labeling; Lysine; Mass Spectrometry; Methionine; Molecular Sequence Data; Peptides; Proteolysis; Proteomics; Radioisotope Dilution Technique; Reference Standards; Trypsin | 2012 |
Electrochemistry/mass spectrometry as a tool in the investigation of the potent skin sensitizer p-phenylenediamine and its reactivity toward nucleophiles.
Topics: Allergens; Cysteine; Electrochemical Techniques; Glutathione; Lysine; Oxidation-Reduction; Phenylenediamines; Potassium Cyanide; Skin Irritancy Tests; Spectrometry, Mass, Electrospray Ionization | 2012 |
The reactivity of human serum albumin toward trans-4-hydroxy-2-nonenal.
Topics: Aldehydes; Amino Acid Sequence; Cysteine; Histidine; Humans; Kinetics; Lysine; Mass Spectrometry; Molecular Sequence Data; Oxidation-Reduction; Serum Albumin; Thermodynamics | 2012 |
Basic residues R260 and K357 affect the conformational dynamics of the major facilitator superfamily multidrug transporter LmrP.
Topics: Arginine; Bacterial Proteins; Benzalkonium Compounds; Benzimidazoles; Binding Sites; Biological Transport; Cell Membrane; Cross-Linking Reagents; Cysteine; Drug Resistance, Multiple; Ethidium; Hydrogen-Ion Concentration; Immunoblotting; Lactococcus lactis; Lysine; Membrane Transport Proteins; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Proton-Motive Force; Protons | 2012 |
The role of amino acid residues in the active site of L-methionine γ-lyase from Pseudomonas putida.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Cysteine; Dimerization; Histidine; Hydrogen Bonding; Kinetics; Lysine; Methionine; Models, Molecular; Protein Structure, Secondary; Protein Subunits; Pseudomonas putida; Recombinant Proteins; Substrate Specificity | 2012 |
Characterization of products from the reaction of glucosinolate-derived isothiocyanates with cysteine and lysine derivatives formed in either model systems or broccoli sprouts.
Topics: Brassica; Cysteine; Glucosinolates; Isothiocyanates; Lysine | 2012 |
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Crystallography, X-Ray; Cysteine; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Flavoproteins; Fluorescent Dyes; Kinetics; Lysine; Microbial Sensitivity Tests; Microbial Viability; Models, Molecular; Mutagenesis, Site-Directed; Mycobacterium smegmatis; Mycobacterium tuberculosis; Oxidation-Reduction; Oxidoreductases; Protein Structure, Tertiary; Protein Transport; Subcellular Fractions; Thiazines | 2012 |
Comparative metabolomic study of Penicillium chrysogenum during pilot and industrial penicillin fermentations.
Topics: Culture Media; Cysteine; Fermentation; Humans; Industry; Lysine; Metabolomics; Penicillins; Penicillium chrysogenum; Principal Component Analysis; Valine | 2012 |
Peptide reactivity assay using spectrophotometric method for high-throughput screening of skin sensitization potential of chemical haptens.
Topics: Cysteine; Dermatitis, Contact; Haptens; Humans; Lysine; Peptides; Skin Irritancy Tests; Spectrophotometry | 2013 |
Mechanism-based small molecule cross-linkers of HECT E3 ubiquitin ligase-substrate pairs.
Topics: Binding Sites; Cross-Linking Reagents; Cyclin-Dependent Kinase Inhibitor Proteins; Cysteine; Endosomal Sorting Complexes Required for Transport; Lysine; Peptide Fragments; Saccharomyces cerevisiae Proteins; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Ubiquitination | 2012 |
Synthesis of an activated phosphonated bifunctional chelate with potential for PET imaging and radiotherapy.
Topics: Antibodies, Monoclonal; Biopsy; Chelating Agents; Colonic Neoplasms; Cysteine; Ethylamines; Fluorescent Antibody Technique; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Multimodal Imaging; Neoplasm Proteins; Organophosphonates; Peptides; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staining and Labeling; Tenascin; Tomography, X-Ray Computed | 2012 |
Reactivity of chemical respiratory allergens in the Peroxidase Peptide Reactivity Assay.
Topics: Allergens; Biological Assay; Cysteine; Haptens; Horseradish Peroxidase; Hydrogen Peroxide; Lysine; Peptides; Respiratory Hypersensitivity | 2013 |
Data integration of non-animal tests for the development of a test battery to predict the skin sensitizing potential and potency of chemicals.
Topics: Allergens; Animal Testing Alternatives; B7-2 Antigen; Cell Line; Cysteine; Dermatitis, Allergic Contact; Drug-Related Side Effects and Adverse Reactions; Haptens; Humans; Intercellular Adhesion Molecule-1; Lysine; Models, Biological; Monocytes; Oligopeptides; Predictive Value of Tests; Toxicity Tests | 2013 |
Chemical mutagenesis of vaccinia DNA topoisomerase lysine 167 provides insights to the catalysis of DNA transesterification.
Topics: Base Sequence; Cysteine; DNA Topoisomerases, Type I; DNA, Viral; Esterification; Lysine; Models, Molecular; Mutagenesis; Point Mutation; Vaccinia; Vaccinia virus | 2013 |
Unique requirements for mono- and polyubiquitination of the peroxisomal targeting signal co-receptor, Pex20.
Topics: Binding Sites; Cysteine; Dithiothreitol; Fungal Proteins; Immunoblotting; Lysine; Microscopy, Fluorescence; Models, Biological; Mutation; Peroxisomal Targeting Signal 2 Receptor; Peroxisomes; Pichia; Polyubiquitin; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RING Finger Domains; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2013 |
Structural insights into the recovery of aldolase activity in N-acetylneuraminic acid lyase by replacement of the catalytically active lysine with γ-thialysine by using a chemical mutagenesis strategy.
Topics: Cloning, Molecular; Crystallography, X-Ray; Cysteine; Fructose-Bisphosphate Aldolase; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Oxo-Acid-Lyases; Staphylococcus aureus | 2013 |
Amino acids form strongly bound anions when substituted with superhalogen ligands.
Topics: Anions; Aspartic Acid; Cysteine; Electrons; Halogens; Ligands; Lysine; Models, Molecular | 2013 |
The microtubule-associated tau protein has intrinsic acetyltransferase activity.
Topics: Acetylation; Acetyltransferases; Cysteine; DNA Mutational Analysis; Kinetics; Lysine; Microtubules; Protein Binding; tau Proteins | 2013 |
Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody.
Topics: 3T3-L1 Cells; Animals; Antibodies; Body Weight; Cysteine; Delayed-Action Preparations; Diabetes Mellitus; Energy Metabolism; Fibroblast Growth Factors; Humans; Hypoglycemic Agents; Immunoglobulin Fab Fragments; Insulin-Secreting Cells; Lysine; Macaca fascicularis; Male; Mice; Mice, Obese; Molecular Mimicry; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2013 |
Evaluating the conformation and binding interface of cap-binding proteins and complexes via ultraviolet photodissociation mass spectrometry.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Dithiothreitol; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4F; Eukaryotic Initiation Factor-4G; Guanosine Triphosphate; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Plant Proteins; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Triticum | 2013 |
Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cysteine; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Histone-Lysine N-Methyltransferase; Histones; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Lysine; Mass Spectrometry; Methylation; Models, Molecular; Mutation; Myeloid-Lymphoid Leukemia Protein; Nuclear Proteins; Protein Structure, Tertiary; Transcription Factors | 2014 |
Predicted multiple selected reaction monitoring to screen activated drug-mediated modifications on human serum albumin.
Topics: Amino Acid Sequence; Benzoquinones; Binding Sites; Cysteine; Humans; Imines; Ketoprofen; Lysine; Mass Spectrometry; Molecular Sequence Data; Pharmaceutical Preparations; Protein Binding; Serum Albumin | 2014 |
Method for detecting the reactivity of chemicals towards peptides as an alternative test method for assessing skin sensitization potential.
Topics: Cosmetics; Cysteine; Haptens; High-Throughput Screening Assays; Lysine; Oligopeptides; Skin Irritancy Tests; Spectrophotometry | 2014 |
Protonation states of active-site lysines of penicillin-binding protein 6 from Escherichia coli and the mechanistic implications.
Topics: Cysteine; Escherichia coli; Escherichia coli Proteins; Hydrogen-Ion Concentration; Lysine; Molecular Dynamics Simulation; Penicillin-Binding Proteins; Protons; Thermodynamics | 2014 |
A mechanistic approach to modeling respiratory sensitization.
Topics: Air Pollutants, Occupational; Allergens; Animals; Biological Availability; Cysteine; Dermatitis, Allergic Contact; Humans; Liver; Lung; Lysine; Models, Biological; Peptides; Protein Binding; Respiratory Hypersensitivity; Risk Assessment; Skin; Structure-Activity Relationship | 2014 |
ND3, ND1 and 39kDa subunits are more exposed in the de-active form of bovine mitochondrial complex I.
Topics: Amino Acid Sequence; Animals; Cattle; Cysteine; Electron Transport Complex I; Electrophoresis, Polyacrylamide Gel; Fluorescence; Lysine; Mass Spectrometry; Molecular Sequence Data; NAD; Oxidation-Reduction | 2014 |
Glutathione-mediated reversibility of covalent modification of ubiquitin carboxyl-terminal hydrolase L1 by 1,2-naphthoquinone through Cys152, but not Lys4.
Topics: Blotting, Western; Cell Line, Tumor; Cysteine; Electrophoresis, Gel, Two-Dimensional; Glutathione; Humans; Lysine; Naphthoquinones; Recombinant Proteins; Ubiquitin Thiolesterase; Ubiquitination | 2014 |
Genetically encoding an electrophilic amino acid for protein stapling and covalent binding to native receptors.
Topics: Amino Acyl-tRNA Synthetases; Cross-Linking Reagents; Cysteine; Histidine; Humans; Lysine; Methanosarcina; Myoglobin; Protein Binding; Protein Conformation; Protein Engineering; Receptor, ErbB-2; Recombinant Proteins | 2014 |
Family-wide analysis of poly(ADP-ribose) polymerase activity.
Topics: Adenosine Diphosphate Ribose; Amino Acid Motifs; Cells, Cultured; Cysteine; Humans; Lysine; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases | 2014 |
Utilization of potato starch processing wastes to produce animal feed with high lysine content.
Topics: Amino Acids; Animal Feed; Animals; Aspergillus niger; Bacillus; Biomass; Bioreactors; Candida; Cellulose; Cysteine; Dietary Proteins; Fermentation; Lysine; RNA, Ribosomal, 16S; Solanum tuberosum; Starch; Toxicity Tests, Acute | 2015 |
Protein modification by adenine propenal.
Topics: Adenine; Amino Acid Sequence; Chromatography, High Pressure Liquid; Cysteine; Fluorescence Polarization; Humans; Lysine; Molecular Sequence Data; Peptides; Serum Albumin; Tandem Mass Spectrometry; Xeroderma Pigmentosum Group A Protein | 2014 |
Cys(i)-Lys(i+3)-Lys(i+4) triad: a general approach for PEG-based stabilization of α-helical proteins.
Topics: Amino Acid Sequence; Cysteine; Lysine; Molecular Sequence Data; Polyethylene Glycols; Protein Structure, Secondary; Proteins | 2014 |
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues.
Topics: Acetylcysteine; Albumins; Apoptosis; Arginine; Aspartate Aminotransferases; Catalysis; Cell Survival; Cysteine; Escherichia coli; Fructose-Bisphosphate Aldolase; Glucose; Glycolates; Glyoxal; Humans; Intracellular Signaling Peptides and Proteins; Lactates; Lysine; Mass Spectrometry; Oncogene Proteins; Oxidative Stress; Parkinsonian Disorders; Protein Deglycase DJ-1; Pyruvaldehyde | 2015 |
Use of chimeras, point mutants, and molecular modeling to map the antagonist-binding site of 4,4',4″,4‴-(carbonylbis-(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakisbenzene-1,3-disulfonic acid (NF449) at P2X1 receptors for ATP.
Topics: Adenosine Triphosphate; Animals; Benzenesulfonates; Binding Sites; Cysteine; Drug Design; Humans; Ligands; Lysine; Mice; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Protein Binding; Purinergic P2X Receptor Antagonists; Rats; Suramin; Xenopus laevis | 2015 |
Small molecule inhibitors of disulfide bond formation by the bacterial DsbA-DsbB dual enzyme system.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cysteine; Disulfides; Drug Design; Drug Evaluation, Preclinical; Escherichia coli Proteins; Humans; Inhibitory Concentration 50; Lysine; Membrane Proteins; Protein Disulfide-Isomerases; Small Molecule Libraries; Structure-Activity Relationship; Thioredoxins; Ubiquinone | 2015 |
13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1.
Topics: Antiporters; Carbon Radioisotopes; Carbon-13 Magnetic Resonance Spectroscopy; Chloride-Bicarbonate Antiporters; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Lysine; Methionine; Methylation; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Structure, Tertiary | 2015 |
QTL for seed protein and amino acids in the Benning × Danbaekkong soybean population.
Topics: Amino Acids; Cysteine; Genetic Linkage; Glycine max; Lysine; Methionine; Microsatellite Repeats; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Seed Storage Proteins; Threonine | 2015 |
Isolation, identification, and formation conditions of a novel Maillard yellowish pigment, pyrrolothiazolate.
Topics: Coloring Agents; Cysteine; Glucose; Lysine; Maillard Reaction; Pyrroles; Thiazines | 2015 |
A novel in chemico method to detect skin sensitizers in highly diluted reaction conditions.
Topics: Animal Testing Alternatives; Biological Assay; Chromatography, High Pressure Liquid; Cysteine; Databases, Factual; Humans; Hydrogen-Ion Concentration; Lysine; Naphthalenes; Peptides; Reproducibility of Results; Skin | 2015 |
Distinct Paths for Basic Amino Acid Export in Escherichia coli: YbjE (LysO) Mediates Export of L-Lysine.
Topics: Amino Acid Transport Systems, Basic; Biological Transport; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genotype; Lysine; Mutation; Plasmids | 2015 |
Does the Transcription Factor NemR Use a Regulatory Sulfenamide Bond to Sense Bleach?
Topics: Cysteine; Escherichia coli; Escherichia coli Proteins; Hypochlorous Acid; Lysine; Oxidation-Reduction; Sulfamerazine; Transcription Factors | 2015 |
Alternative Protein Secretion in the Malaria Parasite Plasmodium falciparum.
Topics: Adenylate Kinase; ADP-Ribosylation Factor 1; Amino Acid Motifs; Animals; Cell Membrane; Cysteine; Erythrocytes; Golgi Apparatus; Green Fluorescent Proteins; Humans; Lysine; Malaria, Falciparum; Parasites; Plasmodium falciparum; Protein Sorting Signals; Protein Transport; Protozoan Proteins; Secretory Pathway; Vacuoles | 2015 |
[Can a sensitizer potency be attenuated?].
Topics: Acrolein; Animals; Antioxidants; Brassicaceae; Carrier Proteins; Cysteine; Dinitrochlorobenzene; Haptens; Hazardous Substances; Humans; Isocyanates; Lysine; Mice; NF-E2-Related Factor 2; Occupational Exposure; Occupational Health; Oxidative Stress; Protein Binding; Reactive Oxygen Species; Skin Irritancy Tests; Tricarboxylic Acids | 2015 |
Synthesis of histone proteins by CPE ligation using a recombinant peptide as the C-terminal building block.
Topics: Automation, Laboratory; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Combinatorial Chemistry Techniques; Cysteine; Dipeptides; Histones; Humans; Japan; Lysine; Methylation; Models, Molecular; Oligopeptides; Peptide Fragments; Protein Processing, Post-Translational; Recombinant Proteins; Solid-Phase Synthesis Techniques; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2015 |
The DJ-1 superfamily member Hsp31 repairs proteins from glycation by methylglyoxal and glyoxal.
Topics: Arginine; Cysteine; Escherichia coli Proteins; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Glyoxal; Lysine; Molecular Chaperones; Pyruvaldehyde; Schiff Bases | 2015 |
Cysteine-specific ubiquitination protects the peroxisomal import receptor Pex5p against proteasomal degradation.
Topics: Cysteine; Gene Deletion; Lysine; Membrane Transport Proteins; Peroxins; Peroxisome-Targeting Signal 1 Receptor; Peroxisomes; Proteasome Endopeptidase Complex; Protein Transport; Proteolysis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitination | 2015 |
Detection of cysteine- and lysine-based protein adductions by reactive metabolites of 2,5-dimethylfuran.
Topics: Animals; Cysteine; Furans; Lysine; Male; Mice; Mice, Inbred Strains; Proteins | 2015 |
The Cysteine-rich Domain of the DHHC3 Palmitoyltransferase Is Palmitoylated and Contains Tightly Bound Zinc.
Topics: Amino Acid Motifs; Animals; Biotin; Catalytic Domain; Chelating Agents; Cysteine; Iodoacetamide; Ions; Lipoylation; Lysine; Mass Spectrometry; Membrane Proteins; Metals; Mice; Mutation; Protein Binding; Protein Processing, Post-Translational; Sf9 Cells; Spodoptera; Zinc | 2015 |
N- and S-homocysteinylation reduce the binding of human serum albumin to catechins.
Topics: Aminoacylation; Catechin; Cysteine; Electrophoresis, Capillary; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Ligands; Lysine; Protein Processing, Post-Translational; Serum Albumin; Serum Albumin, Human | 2017 |
Identification of lanthionine and lysinoalanine in heat-treated wheat gliadin and bovine serum albumin using tandem mass spectrometry with higher-energy collisional dissociation.
Topics: Alanine; Animals; Cattle; Chymotrypsin; Cysteine; Cystine; Gliadin; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Lysinoalanine; Proteolysis; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Triticum; Trypsin | 2016 |
New Insights into Peptide-Silver Nanoparticle Interaction: Deciphering the Role of Cysteine and Lysine in the Peptide Sequence.
Topics: Cysteine; Lysine; Metal Nanoparticles; Peptides; Silver | 2016 |
High-Throughput Mass Spectrometric Analysis of Covalent Protein-Inhibitor Adducts for the Discovery of Irreversible Inhibitors: A Complete Workflow.
Topics: Acrylamide; Cysteine; High-Throughput Screening Assays; Lysine; Mass Spectrometry; Proteins; Solid Phase Extraction | 2016 |
S- to N-Palmitoyl Transfer During Proteomic Sample Preparation.
Topics: Amino Acid Sequence; Cysteine; Isomerism; Lipoylation; Lysine; Peptides; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2016 |
Effect of Cysteamine on Mutant ASL Proteins with Cysteine for Arginine Substitutions.
Topics: Amino Acid Substitution; Arginine; Argininosuccinate Lyase; Cell Survival; Cysteamine; Cysteine; Gene Expression Regulation; HEK293 Cells; Humans; Lysine; Models, Molecular; Molecular Docking Simulation | 2016 |
In situ chemical behaviour of methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) in reconstructed human epidermis: a new approach to the cross-reactivity issue.
Topics: Cross Reactions; Cysteine; Epidermis; Histidine; Humans; Lysine; Magnetic Resonance Spectroscopy; Sulfhydryl Compounds; Thiazoles | 2016 |
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Topics: Aspartic Acid; Autolysis; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Lysine; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Protein Precursors; Proteolysis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine | 2016 |
Investigations on the reactions of α-dicarbonyl compounds with amino acids and proteins during in vitro digestion of biscuits.
Topics: Amino Acids; Cysteine; Deoxyglucose; Dietary Proteins; Digestion; Lysine; Mass Spectrometry; Models, Biological; Ovalbumin; Pyruvaldehyde | 2016 |
Ubiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targeting.
Topics: Animals; Antibodies; Cell Line, Transformed; Cysteine; Cysteine Proteinase Inhibitors; Down-Regulation; Electric Stimulation; Endosomal Sorting Complexes Required for Transport; Gene Expression Regulation; GRB10 Adaptor Protein; HEK293 Cells; Humans; Kv1.3 Potassium Channel; Leupeptins; Lysine; Membrane Potentials; Models, Biological; Mutation; Nedd4 Ubiquitin Protein Ligases; Patch-Clamp Techniques; RNA-Binding Protein FUS; Ubiquitin-Protein Ligases; Ubiquitination | 2016 |
On methylene-bridged cysteine and lysine residues in proteins.
Topics: Cysteine; Databases, Protein; Histidinol-Phosphatase; Lysine; Medicago truncatula; Plant Proteins | 2016 |
Development of PEGylated Cysteine-Modified Lysine Dendrimers with Multiple Reduced Thiols To Prevent Hepatic Ischemia/Reperfusion Injury.
Topics: Animals; Cysteine; Dendrimers; Liver; Lysine; Male; Mice; Polyethylene Glycols; Reactive Oxygen Species; Reperfusion Injury; Sulfhydryl Compounds | 2016 |
Crystal structure of a thiolase from Escherichia coli at 1.8 Å resolution.
Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Amino Acid Motifs; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Expression; Kinetics; Lysine; Models, Molecular; Plasmids; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins; Substrate Specificity; Water | 2016 |
Natural Product Splicing Inhibitors: A New Class of Antibody-Drug Conjugate (ADC) Payloads.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Products; Carboxylic Acids; Cell Line, Tumor; Cell Transformation, Neoplastic; Cysteine; Humans; Immunoconjugates; Lysine; Maleimides; Mice; Pyrans; Tissue Distribution | 2016 |
Maleimide-functionalized closo-dodecaborate albumin conjugates (MID-AC): Unique ligation at cysteine and lysine residues enables efficient boron delivery to tumor for neutron capture therapy.
Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cell Line; Cysteine; Drug Carriers; Female; Lysine; Maleimides; Mice; Mice, Inbred BALB C; Models, Molecular; Neoplasms; Serum Albumin, Bovine | 2016 |
Rapid Semisynthesis of Acetylated and Sumoylated Histone Analogs.
Topics: Acetylation; Animals; Cloning, Molecular; Cysteine; Disulfides; Histones; Humans; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Recombinant Proteins; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Ubiquitins | 2016 |
New insights about the structural rearrangements required for substrate translocation in the bovine mitochondrial oxoglutarate carrier.
Topics: Animals; Arginine; Binding Sites; Cattle; Cysteine; Ethyl Methanesulfonate; Gene Expression; Ketoglutaric Acids; Kinetics; Lysine; Membrane Transport Proteins; Mitochondria; Mitochondrial ADP, ATP Translocases; Molecular Docking Simulation; Mutagenesis, Site-Directed; Protein Binding; Protein Domains; Protein Structure, Secondary; Structural Homology, Protein; Substrate Specificity | 2016 |
An allosteric disulfide bond is involved in enhanced activation of factor XI by protein disulfide isomerase.
Topics: Allosteric Site; Animals; Avidin; Binding Sites; Blood Coagulation; Coagulants; Cricetinae; Cysteine; Disulfides; Factor IX; Factor XI; Humans; Lysine; Molecular Dynamics Simulation; Mutation; Protein Disulfide-Isomerases; Protein Folding; Thrombin | 2016 |
Probing the proton channels in subunit N of Complex I from Escherichia coli through intra-subunit cross-linking.
Topics: Cross-Linking Reagents; Cysteine; Databases, Protein; Electron Transport Complex I; Escherichia coli; Escherichia coli Proteins; Lysine; Maleimides; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; NADH Dehydrogenase; Oxidation-Reduction; Oxidative Phosphorylation; Periplasm; Polyethylene Glycols; Protein Conformation, alpha-Helical; Protein Structure, Tertiary; Protein Subunits; Protons; Structure-Activity Relationship; Ubiquitin | 2016 |
CO and NO bind to Fe(II) DiGeorge critical region 8 heme but do not restore primary microRNA processing activity.
Topics: Binding Sites; Carbon Monoxide; Circular Dichroism; Cysteine; Ferric Compounds; Ferrous Compounds; Heme; Histidine; Humans; Hydrogen-Ion Concentration; Ligands; Lysine; MicroRNAs; Models, Biological; Nitric Oxide; Protein Binding; RNA-Binding Proteins; Spectrum Analysis, Raman | 2016 |
Lysine- and cysteine-based protein adductions derived from toxic metabolites of 8-epidiosbulbin E acetate.
Topics: Activation, Metabolic; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Dioscorea; Diterpenes; In Vitro Techniques; Ketoconazole; Lysine; Male; Medicine, East Asian Traditional; Mice; Microsomes, Liver; Oxidation-Reduction; Proteins | 2016 |
Comfortably Numb and Back: Plasma Metabolomics Reveals Biochemical Adaptations in the Hibernating 13-Lined Ground Squirrel.
Topics: Animals; Arginine; Body Temperature; Cystathionine; Cysteine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Hibernation; Hydrogen Sulfide; Lysine; Male; Metabolomics; Methionine; Periodicity; Sciuridae; Seasons | 2017 |
The cysteine-rich domain of TET2 binds preferentially to mono- and dimethylated histone H3K36.
Topics: Binding Sites; Chromatin; Cysteine; Dioxygenases; DNA-Binding Proteins; HEK293 Cells; Histones; Humans; Immunoblotting; Lysine; Methylation; Microscopy, Confocal; Models, Molecular; Mutation, Missense; Protein Binding; Protein Domains; Proto-Oncogene Proteins | 2017 |
H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase.
Topics: Allosteric Regulation; Binding Sites; Catalytic Domain; Chromatin; Cysteine; DNA; DNA Methylation; Genes, RAG-1; Histones; Lysine; Plant Physiological Phenomena; Plant Proteins; Protein Binding; Protein Conformation; V(D)J Recombination; VDJ Recombinases | 2017 |
Irreversible Cysteine-Selective Protein Labeling Employing Modular Electrophilic Tetrafluoroethylation Reagents.
Topics: Amines; Carbodiimides; Cysteine; Iodine; Lysine; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds | 2017 |
Non-enzymatic N-acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S-acetylated Thiol Intermediate Sensitive to Glyoxalase II.
Topics: Acetyl Coenzyme A; Acetylation; Cysteine; Fatty Acid Synthases; Humans; Lysine; Mitochondria; Mitochondrial Proteins; Recombinant Proteins; Sirtuin 3; Sulfhydryl Compounds; Thiolester Hydrolases | 2017 |
A Metabolic Function for Phospholipid and Histone Methylation.
Topics: Cysteine; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Histones; Lysine; Methylation; Mutation; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Protein Phosphatase 2; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Transcription, Genetic | 2017 |
In vitro assessment of skin sensitization, photosensitization and phototoxicity potential of commercial glyphosate-containing formulations.
Topics: Animal Testing Alternatives; Animals; BALB 3T3 Cells; Cysteine; Dermatitis, Phototoxic; Drug Compounding; Glycine; Glyphosate; Herbicides; Humans; Lysine; Mice; Neutral Red; Photosensitivity Disorders; Skin; Ultraviolet Rays | 2017 |
Amino acid composition of rumen bacteria and protozoa in cattle.
Topics: Alanine; Amino Acids; Animal Feed; Animals; Bacteria; Bacterial Proteins; Cattle; Cysteine; Digestion; Duodenum; Lysine; Methionine; Protozoan Proteins; Rumen | 2017 |
Discovery and Characterization of Histidine Oxidation Initiated Cross-links in an IgG1 Monoclonal Antibody.
Topics: Antibodies, Monoclonal; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Histidine; Immunoglobulin G; Lysine; Mass Spectrometry; Molecular Weight; Oxidation-Reduction; Peptide Mapping; Peptides | 2017 |
Chemical Identity of Interaction of Protein with Reactive Metabolite of Diosbulbin B In Vitro and In Vivo.
Topics: Activation, Metabolic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Glutathione; Heterocyclic Compounds, 4 or More Rings; Ketoconazole; Liver; Lysine; Male; Mice; Microsomes, Liver; Proteins | 2017 |
Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells.
Topics: Aldehydes; Amides; Cell Line; Cysteine; Histone Code; Humans; Lipid Peroxidation; Lysine; Oxidation-Reduction; Proteome; Proteomics; Pyrroles; Schiff Bases | 2017 |
Systematic and Quantitative Assessment of Hydrogen Peroxide Reactivity With Cysteines Across Human Proteomes.
Topics: Amino Acid Motifs; Cell Line, Tumor; Computer Simulation; Cysteine; HEK293 Cells; Hep G2 Cells; Humans; Hydrogen Peroxide; Lysine; Oxidation-Reduction; Protein Conformation; Proteome; Proteomics | 2017 |
Protein Repair from Glycation by Glyoxals by the DJ-1 Family Maillard Deglycases.
Topics: Acrylamide; Animals; Arginine; Bacteria; Bacterial Proteins; Cysteine; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Maillard Reaction; Protein Deglycase DJ-1; Protein Processing, Post-Translational | 2017 |
Native-MS Analysis of Monoclonal Antibody Conjugates by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.
Topics: Antibodies, Monoclonal; Biotin; Cysteine; Immunoconjugates; Immunoglobulin G; Lysine; Mass Spectrometry | 2018 |
Protein acetylation: an important mechanism in actinobacteria.
Topics: Acetylation; Actinobacteria; Amino Acid Sequence; Cysteine; Lysine; Protein Processing, Post-Translational | 2018 |
Palladium Oxidative Addition Complexes for Peptide and Protein Cross-linking.
Topics: Cross-Linking Reagents; Cysteine; Lysine; Molecular Conformation; Organometallic Compounds; Oxidation-Reduction; Palladium; Peptides; Proteins | 2018 |
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.
Topics: Biocatalysis; Catalytic Domain; Cysteine; Deubiquitinating Enzymes; HEK293 Cells; HeLa Cells; Humans; Lysine; Molecular Probes; Protein Processing, Post-Translational; Proteomics; Replication Protein A; Staining and Labeling; Sumoylation; Ubiquitination | 2018 |
A mass spectrometry approach for the identification and localization of small aldehyde modifications of proteins.
Topics: Acrolein; Aldehydes; Chromatography, Liquid; Cysteine; Histidine; Humans; Lysine; Muramidase; Oxidation-Reduction; Peptide Fragments; Serum Albumin, Human; Tandem Mass Spectrometry | 2018 |
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.
Topics: Adaptor Proteins, Signal Transducing; Biocatalysis; Cell Line, Tumor; Crystallography, X-Ray; Cysteine; Esterification; HEK293 Cells; Humans; Lysine; Models, Molecular; Protein Domains; Proteomics; Serine; Substrate Specificity; Threonine; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2018 |
A protein structure-guided covalent scaffold selectively targets the B1 and B2 subclass metallo-β-lactamases.
Topics: Amino Acid Sequence; Azoles; beta-Lactamase Inhibitors; beta-Lactamases; Catalytic Domain; Cysteine; Escherichia coli; Fluorescent Dyes; Isoindoles; Lysine; Organoselenium Compounds; Rhodamines | 2018 |
Computation-Guided Rational Design of a Peptide Motif That Reacts with Cyanobenzothiazoles via Internal Cysteine-Lysine Relay.
Topics: Amino Acid Sequence; Cell Surface Display Techniques; Computer Simulation; Cysteine; Lysine; Models, Molecular; Peptides; Protein Conformation | 2018 |
In Vitro Determination of Protein Conjugates in Human Cells by LC-ESI-MS/MS after Benzyl Isothiocyanate Exposure.
Topics: Cells; Cysteine; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Isothiocyanates; Lysine; Protein Stability; Proteins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2018 |
The mimics of N
Topics: Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lysine; Molecular Structure; Sirtuins; Small Molecule Libraries; Structure-Activity Relationship | 2018 |
DNA-Encoded Protein Janus Nanoparticles.
Topics: Amino Acid Sequence; Anisotropy; Crystallization; Cysteine; DNA; Gold; Green Fluorescent Proteins; Lysine; Metal Nanoparticles; Mutation; Oligodeoxyribonucleotides; Particle Size; Scattering, Small Angle; Silver; X-Ray Diffraction | 2018 |
Proximal Cysteines that Enhance Lysine N-Acetylation of Cytosolic Proteins in Mice Are Less Conserved in Longer-Living Species.
Topics: Acetylation; Animals; Cysteine; Cytosol; Lysine; Mice | 2018 |
A novel method for site-specific chemical SUMOylation: SUMOylation of Hsp90 modulates co-chaperone binding in vitro.
Topics: Binding Sites; Cysteine; HSP90 Heat-Shock Proteins; Humans; Lysine; Sumoylation | 2019 |
Metabolomic Profiling of Infants With Recurrent Wheezing After Bronchiolitis.
Topics: Bronchiolitis; Case-Control Studies; Citric Acid; Citric Acid Cycle; Cysteine; Female; Humans; Infant; Infant, Newborn; Lysine; Male; Metabolic Networks and Pathways; Metabolomics; Methionine; Prospective Studies; Recurrence; Respiratory Sounds; Risk Factors | 2019 |
High doses of phytase on growth performance and apparent ileal amino acid digestibility of broilers fed diets with graded concentrations of digestible lysine.
Topics: 6-Phytase; Amino Acids; Animal Feed; Animals; Chickens; Cysteine; Diet; Dietary Supplements; Digestion; Ileum; Lysine; Male; Weight Gain | 2019 |
Disulfide bridge formation influences ligand recognition by the ATAD2 bromodomain.
Topics: Adenosine Triphosphatases; ATPases Associated with Diverse Cellular Activities; Crystallography, X-Ray; Cysteine; Disulfides; DNA-Binding Proteins; Histones; Humans; Ligands; Lysine; Molecular Dynamics Simulation; Mutation; Protein Binding; Protein Domains; Solubility; Thermodynamics | 2019 |
Crystallographic identification of spontaneous oxidation intermediates and products of protein sulfhydryl groups.
Topics: Cysteine; Histidinol-Phosphatase; Lysine; Medicago truncatula; Models, Molecular; Oxidation-Reduction; Plant Proteins; Protein Conformation; Sulfhydryl Compounds; Thermodynamics | 2019 |
Chemistry for Covalent Modification of Endogenous/Native Proteins: From Test Tubes to Complex Biological Systems.
Topics: Amino Acids, Aromatic; Animals; Cysteine; Humans; Lysine; Methionine; Molecular Probes; Proteins; Proteome | 2019 |
Dinitroimidazoles as bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization.
Topics: Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Lysine; Nitroimidazoles; Proteins | 2019 |
Differentiation of selectively labeled peptides using solid-state nanopores.
Topics: Computational Biology; Cysteine; Electrophoresis; Ion Transport; Lysine; Mass Spectrometry; Nanopores; Osmosis; Peptides; Proteins; Silicon | 2019 |
Influence of Nucleophilic Amino Acids on Enzymatic Browning Systems.
Topics: Arginine; Catechin; Catechol Oxidase; Chromatography, High Pressure Liquid; Color; Cysteine; Fruit; Gallic Acid; Lysine; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Plant Proteins; Pyrus | 2019 |
Installation of Trimethyllysine Analogs on Intact Histones via Cysteine Alkylation.
Topics: Alkylation; Animals; Cysteine; Electrophoresis, Polyacrylamide Gel; Histones; Humans; Lysine; Protein Processing, Post-Translational; Retinoblastoma-Binding Protein 2; Spectrometry, Mass, Electrospray Ionization; Xenopus laevis | 2019 |
Assessing Lysine and Cysteine Reactivities for Designing Targeted Covalent Kinase Inhibitors.
Topics: Biocatalysis; Computational Biology; Cysteine; Drug Design; Humans; Lysine; Molecular Dynamics Simulation; Molecular Targeted Therapy; Protein Conformation; Protein Kinase Inhibitors; Protein Kinases | 2019 |
Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator.
Topics: Acetylation; Amino Acid Sequence; Anti-HIV Agents; Benzamides; Cell Line; Cysteine; Fusion Proteins, gag-pol; gag Gene Products, Human Immunodeficiency Virus; HIV; Humans; Lysine; Protein Unfolding; Virus Assembly | 2019 |
γ-Thialysine versus Lysine: An Insight into the Epigenetic Methylation of Histones.
Topics: Cysteine; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Models, Molecular; Substrate Specificity | 2019 |
Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination.
Topics: Catalytic Domain; Cell Line; Crystallography, X-Ray; Cysteine; Gene Expression Regulation; HeLa Cells; Homeostasis; Humans; Lysine; Mitosis; Molecular Dynamics Simulation; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitination | 2019 |
A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation.
Topics: Animals; Antibodies, Monoclonal; Cell Survival; Cysteine; Female; HeLa Cells; Humans; Immunoconjugates; Injections, Intravenous; Lysine; Maytansine; Mice; Mice, SCID; Treatment Outcome; Tumor Burden; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2019 |
High-throughput screening (HTS)-based spectrophotometric direct peptide reactivity assay (Spectro-DPRA) to predict human skin sensitization potential.
Topics: Animal Testing Alternatives; Animals; Cysteine; Feasibility Studies; High-Throughput Screening Assays; Humans; Local Lymph Node Assay; Lysine; Molecular Structure; Oligopeptides; Reproducibility of Results; Risk Assessment; Skin; Skin Irritancy Tests; Spectrophotometry; Structure-Activity Relationship | 2019 |
Efficient Production of Homogeneous Lysine-Based Antibody Conjugates Using Microbial Transglutaminase.
Topics: Antibodies; Cysteine; Glutamine; Humans; Immunoconjugates; Lysine; Protein Engineering; Streptomyces; Substrate Specificity; Transglutaminases | 2019 |
Engineering Antibodies with C-Terminal Sortase-Mediated Modification for Targeted Nanomedicine.
Topics: Amino Acid Sequence; Aminoacyltransferases; Antibodies; Antigens; Azides; Bacterial Proteins; Click Chemistry; Cycloaddition Reaction; Cysteine; Cysteine Endopeptidases; Humans; Immunoconjugates; Lysine; Nanomedicine; Protein Engineering; Recombinant Proteins; Single-Chain Antibodies | 2019 |
Middle-Down Multi-Attribute Analysis of Antibody-Drug Conjugates with Electron Transfer Dissociation.
Topics: Ado-Trastuzumab Emtansine; Brentuximab Vedotin; Chromatography, Reverse-Phase; Cysteine; Electron Transport; Immunoconjugates; Lysine; Tandem Mass Spectrometry | 2019 |
Suppression of aspirin-mediated eosinophil activation by prostaglandin E
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Cysteine; Dinoprostone; Drug Hypersensitivity; Eosinophils; Humans; Ketorolac; Leukotriene B4; Leukotrienes; Lysine; Sodium Salicylate | 2019 |
Study of reactions of Nε-(carboxymethyl) lysine with o-benzoquinones by cyclic voltammetry.
Topics: Benzoquinones; Catechols; Cysteine; Flavonoids; Lysine | 2020 |
Reduction and coordination properties of l-Lysine/l-arginine/l-cysteine for the improvement of the color of cured sausage.
Topics: Arginine; Color; Cysteine; Electron Spin Resonance Spectroscopy; Lysine; Meat Products | 2020 |
Evasion of a Human Cytomegalovirus Entry Inhibitor with Potent Cysteine Reactivity Is Concomitant with the Utilization of a Heparan Sulfate Proteoglycan-Independent Route of Entry.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Antibodies, Neutralizing; Antibodies, Viral; Cell Line; Cysteine; Cytomegalovirus; Cytomegalovirus Infections; Gene Library; Heparan Sulfate Proteoglycans; Humans; Immunity, Humoral; Immunity, Innate; Inhibitory Concentration 50; Lentivirus; Lysine; Membrane Proteins; Mice; Mutation; Viral Envelope Proteins; Virus Internalization; Virus Replication | 2020 |
Selenolysine: A New Tool for Traceless Isopeptide Bond Formation.
Topics: Amino Acids; Cysteine; Humans; Lysine; Peptides; Protein Processing, Post-Translational; Selenium Compounds; Sulfur; SUMO-1 Protein | 2020 |
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Topics: Animals; Antioxidants; Biological Transport; Blood-Brain Barrier; Brain Injuries, Traumatic; Carbon; Cell Death; Cysteine; Disease Models, Animal; Free Radicals; Humans; Lipid Peroxidation; Lysine; Mice; Mice, Inbred C57BL; Morris Water Maze Test; Neurons; Oxidative Stress; Quantum Dots; Reactive Nitrogen Species; Reactive Oxygen Species; Superoxide Dismutase; Tissue Distribution | 2020 |
Enrichment of Cysteine-Containing Peptide by On-Resin Capturing and Fixed Charge Tag Derivatization for Sensitive ESI-MS Detection.
Topics: Animals; Cysteine; Lysine; Mice; Peptides; Tandem Mass Spectrometry | 2020 |
Selective Lysine Modification Enabled by Intramolecular Acyl Transfer.
Topics: Cysteine; Humans; Lysine; Molecular Structure | 2020 |
Development of a chromophore-solid phase peptide reaction assay (C-SPRA) for assessing skin sensitization in vitro.
Topics: Acrolein; Amino Acid Sequence; Animals; Benzothiazoles; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Coloring Agents; Cysteine; Fluorescein-5-isothiocyanate; Immobilized Proteins; Lysine; Microspheres; Peptides; Skin; Sulfhydryl Compounds | 2020 |
Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins.
Topics: Binding Sites; Cysteine; Epigenesis, Genetic; Histones; Humans; Lysine; Methylation; Models, Molecular; Molecular Conformation; Protein Binding; Solid-Phase Synthesis Techniques; Structure-Activity Relationship; Thermodynamics | 2020 |
Engineering Boron Hot Spots for the Site-Selective Installation of Iminoboronates on Peptide Chains.
Topics: Boron; Cysteine; Glutathione; Humans; Lysine; Peptides | 2020 |
Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.
Topics: Adaptor Proteins, Signal Transducing; Animals; Axons; Binding Sites; Cysteine; Female; Gene Knock-In Techniques; Humans; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; RING Finger Domains; Signal Transduction; Structure-Activity Relationship; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2020 |
Global chemical modifications comparison of human plasma proteome from two different age groups.
Topics: Adult; Age Factors; Aged; Blood Proteins; Cysteine; Female; Humans; Lysine; Male; Middle Aged; Phosphorylation; Protein Processing, Post-Translational; Proteome; Proteomics; Tandem Mass Spectrometry; Threonine | 2020 |
Electrophile-Induced Conformational Switch of the Human TRPA1 Ion Channel Detected by Mass Spectrometry.
Topics: Ankyrin Repeat; Cysteine; Humans; Ion Channel Gating; Lysine; Mass Spectrometry; Protein Domains; Sulfhydryl Compounds; TRPA1 Cation Channel | 2020 |
On-chip protein separation with single-molecule resolution.
Topics: Acrylic Resins; Calibration; Cell Line, Tumor; Cysteine; Electrophoresis, Polyacrylamide Gel; Humans; Lysine; Molecular Weight; Neoplasms; Protein Array Analysis; Proteins; Proteomics; Sodium Dodecyl Sulfate | 2020 |
Coupling of HSP72 α-Helix Subdomains by the Unexpected Irreversible Targeting of Lysine-56 over Cysteine-17; Coevolution of Covalent Bonding.
Topics: Adenosine; Cluster Analysis; Cysteine; HSP72 Heat-Shock Proteins; Humans; Lysine; Molecular Docking Simulation; Molecular Dynamics Simulation; Principal Component Analysis; Protein Conformation, alpha-Helical | 2020 |
Mass Spectrometry-Based Solid Phase Peptide Reaction Assay for Detecting Allergenicity Using an Immobilized Peptide-Conjugating Photo-Cleavable Linker.
Topics: Allergens; Animal Testing Alternatives; Animals; Biological Assay; Chromatography, High Pressure Liquid; Cysteine; Humans; Lysine; Mass Spectrometry; Peptides; Skin | 2020 |
A direct peptide reactivity assay using a high-throughput mass spectrometry screening platform for detection of skin sensitizers.
Topics: Allergens; Animal Testing Alternatives; Chromatography, High Pressure Liquid; Cysteine; Dermatitis, Allergic Contact; High-Throughput Screening Assays; Humans; Lysine; Peptides; Reference Standards; Reproducibility of Results; Risk Assessment; Skin; Tandem Mass Spectrometry; Toxicity Tests | 2021 |
Cys-Cys and Cys-Lys Stapling of Unprotected Peptides Enabled by Hypervalent Iodine Reagents.
Topics: Cysteine; Indicators and Reagents; Iodine; Lysine; Molecular Structure; Peptides | 2021 |
An Unsual Cys-Glu-Lys Catalytic Triad is Responsible for the Catalytic Mechanism of the Nitrilase Superfamily: A QM/MM Study on Nit2.
Topics: Aminohydrolases; Animals; Biocatalysis; Cysteine; Density Functional Theory; Glutamic Acid; Lysine; Mice; Models, Molecular | 2021 |
Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction.
Topics: Animals; Bacillus subtilis; Bacterial Proteins; Biosensing Techniques; Brain; Cross-Linking Reagents; Cysteine; Formaldehyde; Humans; Lysine; Mice; Protein Conformation; Reproducibility of Results; Transcription Factors | 2021 |
Reconstruction and analysis of correlation networks based on GC-MS metabolomics data for hypercholesterolemia.
Topics: Adolescent; Adult; Arginine; Biomarkers; Case-Control Studies; Cholesterol; Cysteine; Female; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Humans; Hypercholesterolemia; Lactic Acid; Lysine; Male; Metabolomics; Methionine; Middle Aged; Phosphoric Acids; Urea; Young Adult | 2021 |
A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Topics: Allosteric Regulation; Animals; Conserved Sequence; Cysteine; Databases, Protein; Enzyme Activation; Humans; Lysine; Models, Molecular; Neisseria gonorrhoeae; Nitrogen; Oxidation-Reduction; Oxygen; Sulfur; Transaldolase | 2021 |
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Artificial Cells; Bacterial Outer Membrane Proteins; Cell Encapsulation; Cell-Free System; Cysteine; Escherichia coli; Escherichia coli Proteins; Green Fluorescent Proteins; Lysine; Metabolic Engineering; Protein Biosynthesis; Transcription, Genetic | 2021 |
Critical Evaluation of Low-Molecular Weight Respiratory Sensitizers and Their Protein Reactivity Potential Toward Lysine Residues.
Topics: Allergens; Chromatography, High Pressure Liquid; Cysteine; Lysine; Molecular Weight; Skin | 2021 |
Recognizing lysine-cysteine crosslinks in proteins.
Topics: Cross-Linking Reagents; Cysteine; Lysine | 2021 |
Profile of urinary amino acids and their post-translational modifications (PTM) including advanced glycation end-products (AGEs) of lysine, arginine and cysteine in lean and obese ZSF1 rats.
Topics: Animals; Arginine; Creatinine; Cysteine; Glucose; Glycation End Products, Advanced; Heart Failure; Lysine; Obesity; Protein Processing, Post-Translational; Rats; Stroke Volume | 2022 |
NRVS and DFT of MitoNEET: Understanding the Special Vibrational Structure of a [2Fe-2S] Cluster with (Cys)
Topics: Cysteine; Density Functional Theory; Humans; Hydrogen-Ion Concentration; Iron; Lysine; Magnetic Resonance Spectroscopy; Mitochondrial Proteins; Models, Molecular; Protein Binding; Protein Domains; Sulfur; Vibration | 2021 |
Cysteine derivatives as acetyl lysine mimics to inhibit zinc-dependent histone deacetylases for treating cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cysteine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Zinc | 2021 |
Metabolomic signature of amino acids in plasma of patients with non-segmental Vitiligo.
Topics: Amino Acids; Arginine; Cysteine; Glutamates; Glycine; Histidine; Humans; Lysine; Metabolomics; Ornithine; Proline; Vitiligo | 2021 |
Extending the HSA-Cys34-Adductomics Pipeline to Modifications at Lys525.
Topics: Cysteine; Healthy Volunteers; Humans; Lysine; Male; Models, Molecular; Peptides; Serum Albumin, Human | 2021 |
The protein adduction derived from reactive metabolites of multiple furanoids in cortex Dictamni-treated mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dictamnus; Disease Models, Animal; Drugs, Chinese Herbal; Ethanol; Furans; Glutathione; Liver; Lysine; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Plant Extracts; Plants, Medicinal; Proteins | 2022 |
Widespread occurrence of covalent lysine-cysteine redox switches in proteins.
Topics: COVID-19; Cysteine; Humans; Lysine; Oxidation-Reduction; SARS-CoV-2 | 2022 |
The role of lysine palmitoylation/myristoylation in the function of the TEAD transcription factors.
Topics: Animals; Cysteine; Drosophila; Drosophila Proteins; Intracellular Signaling Peptides and Proteins; Lipoylation; Lysine; Mutant Proteins; Protein Serine-Threonine Kinases; Signal Transduction; TEA Domain Transcription Factors; Trans-Activators | 2022 |
Lysines and cysteines: partners in stress?
Topics: Cysteine; Lysine; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Proteins | 2022 |
Application of direct peptide reactivity assay for assessing the skin sensitization potential of essential oils.
Topics: Cysteine; Lysine; Oils, Volatile; Peptides; Skin | 2022 |
Context-Dependence of the Reactivity of Cysteine and Lysine Residues.
Topics: Amino Acid Sequence; Cysteine; Esters; Lysine; Maleimides | 2022 |
Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation.
Topics: Antibodies, Monoclonal; Cysteine; Immunoconjugates; Lysine | 2022 |
Reversible lysine-targeted probes reveal residence time-based kinase selectivity.
Topics: Animals; Cysteine; Lysine; Mice; Protein Binding; Protein Kinase Inhibitors; Protein Kinases | 2022 |
Construction of Complex Macromulticyclic Peptides via Stitching with Formaldehyde and Guanidine.
Topics: Cysteine; Formaldehyde; Guanidine; Lysine; Peptides | 2022 |
Isolation and characterization of novel antihypertensive bioactive peptides from brassica napus and angiotensin-converting enzyme (ace) inhibition potential.
Topics: Alanine; Angiotensins; Antihypertensive Agents; Arginine; Brassica napus; Cysteine; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Proline; Tandem Mass Spectrometry; Threonine; Tyrosine; Valine | 2022 |
A Dense Layer of Polyethyleneglycol and Zwitterionic Bone Targeting Peptide on the Surface of Stereocomplex Polylactide-Polyethyleneglycol Nanoparticles Improves Shelf-storage Stability and the Serum Compatibility.
Topics: Animals; Aspartic Acid; Cysteine; Hydroxyapatites; Lysine; Mice; Nanoparticles; Peptides; Polyesters; Polyethylene Glycols; Protein Corona; Tamoxifen | 2022 |
Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors.
Topics: Amino Acids; Cysteine; ErbB Receptors; Lysine; Proteome | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Cysteine-Assisted Click-Chemistry for Proximity-Driven, Site-Specific Acetylation of Histones.
Topics: Acetylation; Chromatin; Cysteine; Histones; Lysine; Protein Processing, Post-Translational | 2022 |
Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; Cysteine; Ethylmaleimide; Glutaryl-CoA Dehydrogenase; Humans; Lysine; Mice; Saccharopine Dehydrogenases | 2022 |
Computational Elucidation of the Solvent-Dependent Addition of 4-Hydroxy-2-nonenal (HNE) to Cysteine and Cysteinate Residues.
Topics: Aldehydes; Amino Acids; Antioxidants; Cysteine; Histidine; Lipid Peroxidation; Lysine; Oxidative Stress; Solvents; Water | 2022 |
MitoNEET's Reactivity of Lys55 toward Pyridoxal Phosphate Demonstrates its Activity as a Transaminase Enzyme.
Topics: Cysteine; Glutamates; Histidine; Hydrogen; Iron; Iron-Sulfur Proteins; Ketoglutaric Acids; Lysine; Mitochondrial Proteins; Pyridoxal Phosphate; Sulfur; Transaminases | 2022 |
Tong-Xie-Yao-Fang alleviates diarrhea-predominant irritable bowel syndrome in rats via the GCN2/PERK-eIF2α-ATF4 signaling pathway.
Topics: Activating Transcription Factor 4; Animals; Body Weight; Caspase 3; Cysteine; Diarrhea; Drugs, Chinese Herbal; eIF-2 Kinase; Eukaryotic Initiation Factor-2; gamma-Aminobutyric Acid; Glycine; Irritable Bowel Syndrome; Lysine; Maternal Deprivation; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Trinitrobenzenesulfonic Acid; Water | 2022 |
Light-driven proton transmembrane transport enabled by bio-semiconductor 2D membrane: A general peptide-induced WS
Topics: Aspartic Acid; Biosensing Techniques; Cysteine; Ion Transport; Lysine; Peptides; Protons; Semiconductors | 2022 |
Traceless cysteine-linchpin enables precision engineering of lysine in native proteins.
Topics: Cysteine; Immunoconjugates; Lysine; Protein Engineering; Proteins | 2022 |
Heat Capacities of L-Cysteine, L-Serine, L-Threonine, L-Lysine, and L-Methionine.
Topics: Cysteine; Hot Temperature; Lysine; Methionine; Serine; Threonine | 2023 |
[Pseudotargeted metabolomics analysis of pine pollen intervention in the liver of premature ovarian failure rats].
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Cyclophosphamide; Cysteine; Drugs, Chinese Herbal; Estrogens; Female; Humans; Liver; Lysine; Metabolomics; Primary Ovarian Insufficiency; Purines; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2023 |
Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.
Topics: Cross-Linking Reagents; Cysteine; HEK293 Cells; Humans; Lysine; Mass Spectrometry; Peptides; Proteome; Sulfoxides | 2023 |
Role of K364 next to the active site cysteine in voltage-dependent phosphatase activity of Ci-VSP.
Topics: Amino Acids; Animals; Catalytic Domain; Cysteine; Lysine; Mammals; Phosphatidylinositol Phosphates; Phosphoric Monoester Hydrolases; Zebrafish | 2023 |
A search for acrolein scavengers among food components.
Topics: Acrolein; Animals; Cysteine; Lysine; Mice; Quality of Life; Stroke | 2023 |
Ferrihydrite synthesis in the presence of amino acids and artificial seawater.
Topics: Adsorption; Amino Acids; Aspartic Acid; Cysteine; Ferric Compounds; Glycine; Iron; Lysine; Methionine; Minerals; Seawater; Spectroscopy, Fourier Transform Infrared; Water | 2023 |
Lysine long-chain fatty acylation regulates the TEAD transcription factor.
Topics: Acylation; Cysteine; Lysine; Signal Transduction; TEA Domain Transcription Factors; Transcription Factors | 2023 |
Dietary amino acids and anthropometric indices: Tehran Lipid and Glucose Study.
Topics: Adult; Amino Acids; Aspartic Acid; Body Mass Index; Cysteine; Glutamates; Humans; Iran; Lipids; Lysine; Obesity; Overweight; Risk Factors; Tryptophan; Waist Circumference | 2023 |
Structural characterisation and pH-dependent preference of pyrrole cross-link isoforms from reactions of oxoenal with cysteine and lysine side chains as model systems.
Topics: Amines; Amino Acids; Cysteine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Protein Isoforms; Pyrroles | 2023 |
Functional Peptide-Modified Liposomes for siRNA Delivery to Rat Retinal Pigment Epithelium Cells: Effect of Peptide Sequences.
Topics: Amino Acid Sequence; Animals; Arginine; Cysteine; Liposomes; Lysine; Peptides; Rats; Retinal Pigment Epithelium; RNA, Small Interfering; Transfection | 2023 |
Lysine-Reactive
Topics: Agammaglobulinaemia Tyrosine Kinase; Cysteine; Lysine; Piperidines; Protein Kinase Inhibitors; Sulfanilamide; Sulfonamides | 2023 |
A simple method for developing lysine targeted covalent protein reagents.
Topics: Cysteine; Indicators and Reagents; Lysine; Methacrylates; Peptides; Proteins | 2023 |