lysine has been researched along with camptothecin in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 13 (56.52) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, PK | 1 |
| Bjornsti, MA; Fink, GR; Levin, NA | 1 |
| Bargonetti, J; Chicas, A; Kramer, FR; Olivier, M; Taya, Y; Tyagi, S; Xiao, G | 1 |
| Beck, WT; D'Arpa, P; Hashimoto, K; Mo, YY; Moitra, PK; Rallabhandi, P | 1 |
| Erster, S; Moll, UM; Nemajerova, A | 1 |
| Hawke, D; Kobayashi, R; Masumoto, H; Verreault, A | 1 |
| Barman, HK; Nakayama, T; Nishijima, H; Ono, T; Sanematsu, F; Shibahara, K; Takami, Y | 1 |
| Castelli, S; Chillemi, G; Desideri, A; Fiorani, P; Losasso, C | 1 |
| Han, J; Horazdovsky, B; Xu, RM; Zhang, K; Zhang, Z; Zhou, H | 1 |
| Abe, T; Goto, J; Hishinuma, T; Kobayashi, M; Mano, N; Okada, M; Takeuchi, T; Unno, M; Yamaguchi, H | 1 |
| Beckman, EJ; Petoud, S; Pollack, IF; Sivak, WN; Zamboni, WC; Zhang, J | 2 |
| Benedetti, P; Chillemi, G; D'Annessa, I; Desideri, A; Fiorani, P; Losasso, C | 1 |
| Beckman, EJ; Petoud, S; Sivak, WN; Zhang, J | 2 |
| Abraham, RT; Aslanian, A; Brognard, J; Coughlin, C; Dolled-Filhart, M; Hunter, T; Manning, G; You, Z; Zhang, YW | 1 |
| Anderson, S; Baker, SP; Grant, PA; Hunt, DF; Phillips, J; Qiu, Q; Shabanowitz, J; Smith, MM; Yates, JR | 1 |
| Beese-Sims, SE; Colaiácovo, MP; Nottke, AC; Pantalena, LF; Reinke, V; Shi, Y | 1 |
| Bacal, J; Dorn, J; Kaiser, GS; Lee, EH; Lisby, M; Maddox, P; Pasero, P; St-Hilaire, E; Tsao, S; Verreault, A; Wurtele, H | 1 |
| Ding, J; Geng, M; Huang, M; Lin, C; Lu, J; Luo, C; Sun, W; Xie, Z; Yuan, S; Zeng, H | 1 |
| Croce, CM; Kim, A; Kim, SH; King, S; Parquette, JR; Shieh, A; Sun, HL; Sun, Y | 1 |
| Li, G; Zhao, L; Zhao, M | 1 |
| Chen, M; Chen, X; Guo, Z; Liang, R; Tian, H; Wang, Z | 1 |
23 other study(ies) available for lysine and camptothecin
| Article | Year |
|---|---|
Characterization and cellular localization of nucleophosmin/B23 in HeLa cells treated with selected cytotoxic agents (studies of B23-translocation mechanism).
Topics: Autoradiography; Camptothecin; Cell Nucleolus; Dactinomycin; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; HeLa Cells; Humans; Kinetics; Lysine; Methotrexate; Nuclear Proteins; Nucleophosmin; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Protein Processing, Post-Translational; Tritium; Uridine | 1992 |
A novel mutation in DNA topoisomerase I of yeast causes DNA damage and RAD9-dependent cell cycle arrest.
Topics: Alleles; Arginine; Camptothecin; Cell Cycle; Cell Cycle Proteins; DNA Damage; DNA Repair; DNA Topoisomerases, Type I; DNA, Ribosomal; Fungal Proteins; Lysine; Mutation; Recombination, Genetic; Saccharomyces cerevisiae | 1993 |
A DNA damage signal is required for p53 to activate gadd45.
Topics: Acetylation; Androstadienes; Camptothecin; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Deoxyribonuclease I; DNA; DNA Damage; GADD45 Proteins; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Nuclear Proteins; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Serine; Signal Transduction; Transcription, Genetic; Tumor Suppressor Protein p53; Wortmannin | 2000 |
Sumoylation of topoisomerase I is involved in its partitioning between nucleoli and nucleoplasm and its clearing from nucleoli in response to camptothecin.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Arginine; Binding Sites; Camptothecin; Cell Line; Cell Nucleolus; Cell Nucleus; CHO Cells; Cricetinae; Cytoplasm; DNA Topoisomerases, Type I; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Lysine; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Protein Structure, Tertiary; Transfection | 2002 |
The post-translational phosphorylation and acetylation modification profile is not the determining factor in targeting endogenous stress-induced p53 to mitochondria.
Topics: Acetylation; Camptothecin; Cell Line, Tumor; Cell Nucleus; DNA Damage; HCT116 Cells; Humans; Lysine; Mitochondria; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Serine; Tumor Suppressor Protein p53 | 2005 |
A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response.
Topics: Acetylation; Bleomycin; Camptothecin; Cell Cycle; DNA; DNA Damage; DNA Repair; Histones; Lysine; Nucleosomes; Saccharomyces cerevisiae | 2005 |
Histone acetyltransferase 1 is dispensable for replication-coupled chromatin assembly but contributes to recover DNA damages created following replication blockage in vertebrate cells.
Topics: Acetylation; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chickens; Chromatin; DNA Damage; DNA Repair; DNA Replication; G2 Phase; HeLa Cells; Histone Acetyltransferases; Histones; Humans; Kinetics; Lysine; Methyl Methanesulfonate; Microscopy, Fluorescence; Mutation; S Phase | 2006 |
The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant.
Topics: Amino Acid Substitution; Base Sequence; Camptothecin; Catalysis; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Glutamic Acid; Humans; Lysine; Saccharomyces cerevisiae; Substrate Specificity | 2006 |
Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication.
Topics: Acetylation; Amino Acid Sequence; Camptothecin; Catalytic Domain; Chromosome Breakage; DNA Damage; DNA Replication; Histone Acetyltransferases; Histones; Hydroxyurea; Lysine; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Mutation; Recombinant Proteins; S Phase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid | 2007 |
Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes.
Topics: Antineoplastic Agents; Camptothecin; Chenodeoxycholic Acid; Dactinomycin; Docetaxel; Fluorescent Dyes; Humans; Irinotecan; Kinetics; Lysine; Mitoxantrone; Organic Anion Transporters, Sodium-Independent; Paclitaxel; Signal Processing, Computer-Assisted; Solute Carrier Organic Anion Transporter Family Member 1B3; Spectrometry, Fluorescence; Taxoids; Transfection | 2008 |
LDI-glycerol polyurethane implants exhibit controlled release of DB-67 and anti-tumor activity in vitro against malignant gliomas.
Topics: Camptothecin; Cell Death; Cell Line, Tumor; Delayed-Action Preparations; Drug Screening Assays, Antitumor; Glioma; Glycerol; Humans; Isocyanates; Lysine; Microscopy, Electron, Scanning; Organosilicon Compounds; Polyurethanes; Prostheses and Implants; Solutions; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Tablets | 2008 |
Catalyst-dependent drug loading of LDI-glycerol polyurethane foams leads to differing controlled release profiles.
Topics: Antineoplastic Agents; Camptothecin; Catalysis; Delayed-Action Preparations; Diffusion; Drug Compounding; Gases; Isocyanates; Lysine; Materials Testing; Polyurethanes | 2008 |
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations.
Topics: Amino Acid Substitution; Antineoplastic Agents, Phytogenic; Camptothecin; Computer Simulation; DNA; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Lysine; Models, Molecular; Mutation; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Threonine; Topoisomerase I Inhibitors | 2008 |
Simultaneous drug release at different rates from biodegradable polyurethane foams.
Topics: Absorbable Implants; Camptothecin; Delayed-Action Preparations; Diffusion; Doxorubicin; Drug Compounding; Gases; Glycerol; Isocyanates; Kinetics; Lysine; Materials Testing; Organosilicon Compounds; Polyurethanes | 2009 |
Incorporation of ionic ligands accelerates drug release from LDI-glycerol polyurethanes.
Topics: Antineoplastic Agents; Biocompatible Materials; Camptothecin; Chemistry, Pharmaceutical; Choline; Drug Carriers; Drug Delivery Systems; Drug Design; Glycerol; Humans; Ions; Isethionic Acid; Isocyanates; Ligands; Lysine; Organosilicon Compounds; Polyurethanes | 2010 |
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.
Topics: Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; Checkpoint Kinase 1; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Lysine; Neoplasms; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; RNA Interference; SKP Cullin F-Box Protein Ligases; Stress, Physiological; Time Factors; Ubiquitination | 2009 |
Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae.
Topics: Acetylation; Amino Acid Substitution; Camptothecin; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; DNA Replication; Histones; Hydroxyurea; Intracellular Signaling Peptides and Proteins; Lysine; Mutation; Nocodazole; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Proteins; S Phase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine | 2010 |
SPR-5 is a histone H3K4 demethylase with a role in meiotic double-strand break repair.
Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Camptothecin; DNA Breaks, Double-Stranded; DNA Repair; Gene Expression Profiling; Germ Cells; Green Fluorescent Proteins; Histones; Lysine; Meiosis; Methylation; Microscopy, Fluorescence; Mutation; Oligonucleotide Array Sequence Analysis; Oxidoreductases, N-Demethylating; Rad51 Recombinase; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2011 |
Histone H3 lysine 56 acetylation and the response to DNA replication fork damage.
Topics: Acetylation; Antineoplastic Agents; Camptothecin; DNA Damage; DNA Repair; DNA Replication; DNA, Fungal; Histones; Hydroxyurea; Lysine; Methyl Methanesulfonate; Mutagens; Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2012 |
Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents.
Topics: Acetylation; Animals; Camptothecin; HCT116 Cells; Heterografts; Humans; Lysine; Mice; Oxidative Stress; Reactive Oxygen Species; Sirtuin 1; Superoxide Dismutase; Superoxide Dismutase-1 | 2015 |
The self-assembly of a camptothecin-lysine nanotube.
Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrogen-Ion Concentration; Lysine; Molecular Structure; Nanotubes; Particle Size; Structure-Activity Relationship; Temperature | 2016 |
Lysine-mediated hydroxyethyl starch-10-hydroxy camptothecin micelles for the treatment of liver cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hep G2 Cells; Humans; Hydroxyethyl Starch Derivatives; Liver Neoplasms; Lysine; Male; Mice; Mice, Nude; Micelles; Rats, Wistar; Tissue Distribution | 2020 |
Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy.
Topics: Antineoplastic Agents; Arginine; Camptothecin; Cell Line, Tumor; Humans; Lactones; Lysine; Mitochondria; Neoplasms; Prodrugs; Reactive Oxygen Species; Water | 2022 |