Page last updated: 2024-08-17

lysine and bix 01294

lysine has been researched along with bix 01294 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's9 (90.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
August, EM; Hickey, ER; Homon, CA; Jenuwein, T; Kelly, TA; Kowalski, JA; Kubicek, S; Mechtler, K; O'Sullivan, RJ; Rea, S; Teodoro, ML; Zhang, Q1
Bedford, MT; Chang, Y; Cheng, X; Ganesh, T; Horton, JR; Liu, J; Shinkai, Y; Snyder, JP; Spannhoff, A; Sun, A; Zhang, X1
Cabot, RA; Johnson, CM; Park, KE1
Fuchter, MJ; Malmquist, NA; Mecheri, S; Moss, TA; Scherf, A1
Itoi, F; Li, C; Sato, E; Tanemura, K; Terashita, Y; Tokoro, M; Wakayama, S; Wakayama, T; Yamagata, K1
Feng, D; Hu, Q; Li, H; Ma, H; Su, Y; Tao, H; Wang, X; Zhang, C1
Arihiro, K; Doi, S; Doi, T; Irifuku, T; Kohno, N; Masaki, T; Nakashima, A; Sasaki, K; Ueno, T; Yamada, K1
Chao, SB; Huang, XJ; Lin, F; Liu, HL; Ma, XS; Meng, TG; Qin, L; Schatten, H; Sun, QY; Wang, XG; Zhu, CC1
Huang, R; Huang, Y; Jiang, X; Li, M; Yang, X; Yao, J; Yu, M; Zheng, F1
Chatterjee, M; Dworak, N; Jividen, K; Johnson, IG; Kelley, JB; Makosa, D; Paschal, BM; Simke, WC; Snow, C; Yang, CS1

Other Studies

10 other study(ies) available for lysine and bix 01294

ArticleYear
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
    Molecular cell, 2007, Feb-09, Volume: 25, Issue:3

    Topics: Animals; Azepines; Cell Line; Enzyme Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mice; Promoter Regions, Genetic; Protein Methyltransferases; Quinazolines

2007
Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases.
    Journal of molecular biology, 2010, Jul-02, Volume: 400, Issue:1

    Topics: Azepines; Histone Code; Histone-Lysine N-Methyltransferase; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Processing, Post-Translational; Quinazolines

2010
IVMBIX-01294, an inhibitor of the histone methyltransferase EHMT2, disrupts histone H3 lysine 9 (H3K9) dimethylation in the cleavage-stage porcine embryo.
    Reproduction, fertility, and development, 2012, Volume: 24, Issue:6

    Topics: Animals; Azepines; Cleavage Stage, Ovum; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryo Transfer; Embryo, Mammalian; Embryonic Development; Enzyme Inhibitors; Female; Fertilization in Vitro; Gene Expression Regulation, Developmental; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Pregnancy; Pregnancy Rate; Quinazolines; RNA, Messenger; Swine; Time Factors; Transcription, Genetic

2012
Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Oct-09, Volume: 109, Issue:41

    Topics: Amino Acid Sequence; Animals; Antimalarials; Azepines; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Erythrocytes; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Life Cycle Stages; Lysine; Malaria; Methylation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Quinazolines; Sequence Homology, Amino Acid

2012
Latrunculin A treatment prevents abnormal chromosome segregation for successful development of cloned embryos.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Actins; Animals; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Chromosome Segregation; Cloning, Organism; Embryo, Mammalian; Embryonic Development; Epigenesis, Genetic; Female; Fertilization in Vitro; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nuclear Transfer Techniques; Oocytes; Quinazolines; Thiazolidines

2013
Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells.
    Molecular and cellular biochemistry, 2014, Volume: 394, Issue:1-2

    Topics: AC133 Antigen; Antigens, CD; Azepines; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioma; Glycoproteins; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplastic Stem Cells; Peptides; Promoter Regions, Genetic; Quinazolines; Signal Transduction; SOXB1 Transcription Factors; Transfection

2014
Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression.
    Kidney international, 2016, Volume: 89, Issue:1

    Topics: Actins; Animals; Antibodies, Neutralizing; Azepines; Cell Line; Enzyme Inhibitors; Fibroblasts; Fibronectins; Fibrosis; Glomerulonephritis, IGA; Glucuronidase; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Kidney; Klotho Proteins; Lysine; Male; Methylation; Mice; Quinazolines; Rats; RNA, Messenger; RNA, Small Interfering; Transforming Growth Factor beta1; Ureteral Obstruction

2016
The Dynamics and Regulatory Mechanism of Pronuclear H3k9me2 Asymmetry in Mouse Zygotes.
    Scientific reports, 2015, Dec-07, Volume: 5

    Topics: Animals; Azepines; Cell Nucleus; Fertilization in Vitro; Histone-Lysine N-Methyltransferase; Histones; Kruppel-Like Transcription Factors; Lysine; Methylation; Mice; Microinjections; Models, Biological; Nerve Tissue Proteins; Quinazolines; RNA, Small Interfering; Zygote

2015
Beneficial effects of diazepin-quinazolin-amine derivative (BIX-01294) on preimplantation development and molecular characteristics of cloned mouse embryos.
    Reproduction, fertility, and development, 2017, Volume: 29, Issue:6

    Topics: Animals; Azepines; Blastocyst; Cloning, Organism; CpG Islands; DNA Methylation; Ectogenesis; Embryo, Mammalian; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; GRB10 Adaptor Protein; Histone-Lysine N-Methyltransferase; Histones; Lysine; Male; Methylation; Mice; Nuclear Transfer Techniques; Parthenogenesis; Protein Processing, Post-Translational; Quinazolines

2017
A nuclear lamina-chromatin-Ran GTPase axis modulates nuclear import and DNA damage signaling.
    Aging cell, 2019, Volume: 18, Issue:1

    Topics: Active Transport, Cell Nucleus; Azepines; Chromatin; DNA Damage; Fibroblasts; Histones; Humans; Interphase; Lamin Type A; Lysine; Methylation; Nuclear Lamina; Progeria; Quinazolines; ran GTP-Binding Protein; Signal Transduction

2019