lysine and benzyloxycarbonylleucyl-leucyl-leucine aldehyde

Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line; Conserved Sequence; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; Genes, Tumor Suppressor; Humans; Leupeptins; Lysine; Molecular Sequence Data; Multienzyme Complexes; Nuclear Proteins; Proteasome Endopeptidase Complex; Protein Binding; Protein Processing, Post-Translational; Protein Transport; SUMO-1 Protein; Transfection; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Two-Hybrid System Techniques; Ubiquitins

Topics: Acetylcysteine; Apoptosis; Caspase 3; Caspases; Cysteine Endopeptidases; Diamines; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Eukaryotic Translation Initiation Factor 5A; Gene Expression Profiling; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Megakaryoblastic, Acute; Leupeptins; Lysine; Multienzyme Complexes; Oligodeoxyribonucleotides, Antisense; Peptide Initiation Factors; Peptide Mapping; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteomics; RNA-Binding Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Tumor Cells, Cultured; Ubiquitin

Topics: Adipose Tissue; Animals; Blotting, Western; Cysteine Proteinase Inhibitors; Gene Expression Regulation; HeLa Cells; Humans; Hypoglycemic Agents; Leupeptins; Lysine; Mice; Mutagenesis, Site-Directed; NIH 3T3 Cells; Receptors, Cytoplasmic and Nuclear; SUMO-1 Protein; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Transfection

Topics: Amino Acid Substitution; Arginine; Blotting, Western; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Gene Expression; HeLa Cells; Humans; Leupeptins; Lysine; Mutation; Oligopeptides; Peptide Fragments; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Subunits; Proteins; Recombinant Fusion Proteins; Trans-Activators; Transfection; Ubiquitin

Topics: Alkaloids; Amino Acid Substitution; Animals; Arginine; Biological Transport; Blotting, Western; Calnexin; Chlorocebus aethiops; COS Cells; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Goiter; Golgi Apparatus; Heat-Shock Proteins; Humans; Immunoprecipitation; Leupeptins; Lysine; Mice; Molecular Chaperones; Mutation; Protein Binding; Protein Disulfide-Isomerases; Protein Folding; Signal Transduction; Thyroglobulin

Topics: Animals; Cell Line; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Ethylmaleimide; Humans; Leupeptins; Lysine; Mutagenesis, Site-Directed; Mutation; Proteasome Endopeptidase Complex; Protein Transport; Rats; Receptors, Dopamine D2; Signal Transduction; Transfection; Ubiquitin; Ubiquitination

Topics: Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA, Viral; Gene Expression Regulation, Viral; Genome, Viral; Genotype; Hepacivirus; Humans; Leupeptins; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Viral Nonstructural Proteins; Virus Assembly

Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cell Line; Humans; Lafora Disease; Leupeptins; Lysine; Mice; Multiprotein Complexes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Multimerization; Protein Processing, Post-Translational; Protein Stability; Protein Transport; Protein Tyrosine Phosphatases, Non-Receptor; Substrate Specificity; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination

Topics: Amino Acid Sequence; HEK293 Cells; Humans; Immunoprecipitation; Jurkat Cells; Leupeptins; Lysine; Methionine; Molecular Sequence Data; Mutant Proteins; Oxidation-Reduction; Peptide Fragments; Proteasome Inhibitors; Tandem Mass Spectrometry; Ubiquitin; Ubiquitinated Proteins; Ubiquitination

Topics: Acetylation; Genome, Human; HEK293 Cells; Humans; Leupeptins; Lysine; Mass Spectrometry; Peptides; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Proteome; Signal Transduction; Ubiquitin; Ubiquitination

Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cysteine Proteinase Inhibitors; Immunoblotting; Leupeptins; Lysine; Mass Spectrometry; Plants, Genetically Modified; Proteasome Endopeptidase Complex; Proteome; Proteomics; Ubiquitin; Ubiquitinated Proteins; Ubiquitination

Topics: Animals; Cysteine Proteinase Inhibitors; Disease Models, Animal; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Leupeptins; Lysine; Matrix Metalloproteinase 13; Mice, Inbred C57BL; Mice, Transgenic; Osteoarthritis; Proteasome Endopeptidase Complex; Signal Transduction; Ubiquitination; Zinc Fingers

Topics: Benzoquinones; Blotting, Western; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Histone Deacetylase 6; Histone Deacetylases; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leupeptins; Lysine; Microscopy, Confocal; Proteasome Endopeptidase Complex; Protein Aggregates; RNA Interference; Trans-Activators; Ubiquitin; Ubiquitination

Topics: Amino Acid Substitution; Aquaglyceroporins; DNA Mutational Analysis; Leishmania major; Leupeptins; Lysine; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Protein Stability; Protein Transport; Proteolysis

Topics: Animals; Antibodies; Cell Line, Transformed; Cysteine; Cysteine Proteinase Inhibitors; Down-Regulation; Electric Stimulation; Endosomal Sorting Complexes Required for Transport; Gene Expression Regulation; GRB10 Adaptor Protein; HEK293 Cells; Humans; Kv1.3 Potassium Channel; Leupeptins; Lysine; Membrane Potentials; Models, Biological; Mutation; Nedd4 Ubiquitin Protein Ligases; Patch-Clamp Techniques; RNA-Binding Protein FUS; Ubiquitin-Protein Ligases; Ubiquitination

Topics: Cell Line; DNA-Binding Proteins; Endoplasmic Reticulum; Formaldehyde; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Leupeptins; Lysine; Phosphorylation; Polyubiquitin; Proteasome Endopeptidase Complex; Transcription Factors; Ubiquitination

Topics: Amino Acid Sequence; Aminopyridines; Deubiquitinating Enzymes; HEK293 Cells; Humans; Leupeptins; Lysine; Mass Spectrometry; Mitosis; Nocodazole; Polyubiquitin; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Thiocyanates; Ubiquitin

Topics: Cell Line; Cell Nucleus; GTP Phosphohydrolases; GTP-Binding Proteins; Half-Life; HEK293 Cells; Humans; Leupeptins; Lysine; Mutation; Proteasome Endopeptidase Complex; Ubiquitination

Topics: Animals; Cardiomegaly; Fibrosis; Heart Failure; Humans; Isoproterenol; Leupeptins; Lysine; Male; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Myocardium; Poly ADP Ribosylation; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Protein Binding; Proteolysis; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination; Ventricular Remodeling

Topics: Alkylation; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatography, Liquid; Humans; Leupeptins; Lysine; Mass Spectrometry; Mice; Peptides; Proteome; Reference Standards; Software; Ubiquitin