lysine has been researched along with azacitidine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (61.29) | 29.6817 |
| 2010's | 9 (29.03) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Ceman, S; Coffee, B; Reines, D; Warren, ST; Zhang, F | 1 |
| Gonzales, FA; Jones, PA; Liang, G; Lin, JC; Nguyen, CT; Velicescu, M; Weisenberger, DJ | 1 |
| Issa, JP; Kondo, Y; Shen, L | 1 |
| Chen, HB; Costa, M; Kluz, T; Yan, Y; Zhang, P | 1 |
| Felsenfeld, G; Mutskov, V | 1 |
| Higashimoto, K; Joh, K; Kudo, S; Matsukura, S; Matsuo, S; Mukai, T; Nakagawachi, T; Soejima, H; Urano, T; Zhao, W | 1 |
| D'Abreo, C; Fish, JE; Lin, S; Marsden, PA; Matouk, CC; Rachlis, A; Tai, SC | 1 |
| Choi, EJ; Kim, JS; Kim, YH; Seo, JH; Whang, YM; Yoo, YD | 1 |
| Dufau, ML; Fatima, N; Zhang, Y | 1 |
| Horio, Y; Osada, H; Sugito, N; Takahashi, T; Tatematsu, Y | 1 |
| Chen, H; Costa, M; Ke, Q; Kluz, T; Yan, Y | 1 |
| Bates, SE; To, KK; Zhan, Z | 1 |
| Huang, TH; Liu, JC; Plass, C; Potter, D; Smith, LT; Wang, SH; Wu, J; Wu, YZ | 1 |
| Cooper, DA; Kelleher, AD; Lim, HG; Suzuki, K | 1 |
| An, XR; Chen, YF; Cui, XH; Guan, H; Hou, J; Liu, L; Yan, FX; Zhang, J | 1 |
| Li, Z; Yang, N | 1 |
| Chen, Y; Domann, FE; Hitchler, MJ; Weigel, RJ; Woodfield, GW | 1 |
| Hu, XZ; Jiang, H; Lipsky, RH; Marini, AM; Pan, H; Tian, F; Wu, X | 1 |
| Dai, DQ; Meng, CF; Peng, G; Zhu, XJ | 1 |
| Kimmins, S; Lambrot, R | 1 |
| Cho, S; Kang, YK; Lee, D; Park, JS; Shin, ST | 1 |
| Godsey, S; Oyer, JA; Turker, MS; Yates, PA | 1 |
| Au, SL; Ko, FC; Ng, IO; Ng, YL; Wong, CC; Wong, CM | 1 |
| Li, Y; Lu, Q; Luo, Y; Qiu, X; Yuan, J; Zhao, M; Zhong, Q; Zhou, Y | 1 |
| Cavalli, LR; da Costa Prando, E; Rainho, CA | 1 |
| Chen, LH; Cheng, LY; Cherng, CG; Kao, GS; Su, CC; Tzeng, WY; Wang, CY; Yu, L | 1 |
| Chen, PW; Li, H; Mellon, J; Niederkorn, JY; Sadegh, L | 1 |
| Bachmann, M; Mühl, H; Pfeilschifter, J | 1 |
| Darvishi, E; Eddie Loh, YH; Helman, LJ; Hou, X; Hugues Parmentier, J; Mitra, S; Slemmons, K; Wan, Z | 1 |
| Cao, H; Li, F; Lu, Y; Shi, K; Wang, H; Yu, D; Yu, M; Zhou, J | 1 |
31 other study(ies) available for lysine and azacitidine
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome.
Topics: Acetylation; Alleles; Azacitidine; Decitabine; DNA Methylation; Fragile X Mental Retardation Protein; Fragile X Syndrome; Heterochromatin; Histones; Humans; Lysine; Nerve Tissue Proteins; RNA-Binding Proteins; Transcriptional Activation; Trinucleotide Repeats; Tumor Cells, Cultured | 2002 |
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.
Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Culture Techniques; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Gene Silencing; Histones; Humans; Lysine; Methylation; Precipitin Tests; Tumor Cells, Cultured; Tumor Suppressor Protein p14ARF; Urinary Bladder Neoplasms | 2002 |
Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Carrier Proteins; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Methylation; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Precipitin Tests; Promoter Regions, Genetic; Tumor Cells, Cultured | 2003 |
Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure.
Topics: Acetylation; Animals; Azacitidine; Bacterial Proteins; Carcinogens; Chromatin; Clone Cells; Cricetinae; Cricetulus; DNA Methylation; Drug Combinations; Escherichia coli Proteins; Gene Expression; Gene Silencing; Histones; Hydroxamic Acids; Lysine; Nickel; Pentosyltransferases; Precipitin Tests; Proteins; RNA, Messenger; Transgenes | 2003 |
Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9.
Topics: Acetylation; Alpharetrovirus; Animals; Azacitidine; Cell Line; Cell Transformation, Viral; Chickens; Chromatin; CpG Islands; DNA Methylation; Erythroid Cells; Flow Cytometry; Gene Dosage; Gene Silencing; Genes, Reporter; Histones; Kinetics; Lysine; Methylation; Models, Genetic; Polymerase Chain Reaction; Precipitin Tests; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Transcription, Genetic; Transgenes | 2004 |
The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island.
Topics: Azacitidine; Cell Line, Tumor; Chromosomal Proteins, Non-Histone; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Gene Expression; Gene Silencing; Histones; Humans; Hydroxamic Acids; Lysine; Methyl-CpG-Binding Protein 2; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins; Transcription Factors | 2005 |
The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code.
Topics: Acetylation; Animals; Azacitidine; beta-Galactosidase; Blotting, Western; Cell Line; Cell Nucleus; Cells, Cultured; Chromatin; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; Endothelium, Vascular; HeLa Cells; Histones; Humans; Hydroxamic Acids; Lysine; Methylation; Mice; Mice, Transgenic; Models, Genetic; Muscle, Smooth; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nucleosomes; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA Polymerase II; Serine; Time Factors; Transgenes; Umbilical Veins | 2005 |
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells.
Topics: Acetylation; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin | 2005 |
Coordinated changes in DNA methylation and histone modifications regulate silencing/derepression of luteinizing hormone receptor gene transcription.
Topics: Acetylation; Azacitidine; Base Sequence; Chromatin; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression Regulation; Gene Silencing; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, LH; Repressor Proteins; Sin3 Histone Deacetylase and Corepressor Complex; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured; Up-Regulation | 2005 |
Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines.
Topics: Acetylation; Androstadienes; Azacitidine; Chromatin; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lung Neoplasms; Lysine; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Wortmannin | 2005 |
Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing.
Topics: Animals; Azacitidine; Blotting, Western; Carcinoma; Cell Line; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epigenesis, Genetic; Fibroblasts; Gene Silencing; Histones; Humans; Kinetics; Lung Neoplasms; Lysine; Methyltransferases; Mice; Nickel; Trace Elements; Transgenes | 2006 |
Aberrant promoter methylation of the ABCG2 gene in renal carcinoma.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Azacitidine; Base Sequence; Carcinoma, Renal Cell; Cell Line, Tumor; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Histones; Humans; Kidney Neoplasms; Lysine; Neoplasm Proteins; Promoter Regions, Genetic; Protein Binding; Transcription, Genetic; Von Hippel-Lindau Tumor Suppressor Protein | 2006 |
Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing.
Topics: Acetylation; Animals; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation; Gene Silencing; Histones; Hydroxamic Acids; Leukemia L1210; Lysine; Methylation; Mice; Mice, Inbred DBA; Oligonucleotide Array Sequence Analysis; Protein Processing, Post-Translational | 2007 |
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro.
Topics: Acetylation; Azacitidine; CD4 Antigens; Cell Line; Chromatin Immunoprecipitation; DNA Methylation; DNA-Cytosine Methylases; Gene Silencing; HeLa Cells; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Receptors, CCR5; Receptors, CXCR4; RNA, Small Interfering; Simian Immunodeficiency Virus | 2008 |
Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and its relationship with DNA methylation.
Topics: Animals; Azacitidine; DNA Methylation; Embryo, Mammalian; Epigenesis, Genetic; Female; Fluorescent Antibody Technique; Histones; Hydroxamic Acids; Lysine; Mice; Oocytes; Sheep; Zygote | 2008 |
[5-aza-2'-deoxycytidine induces changes of histone H3-lysine 9 methylation in bladder tumor cells].
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Survival; Core Binding Factor Alpha 3 Subunit; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Histones; Humans; Lysine; Methylation; Promoter Regions, Genetic; Time Factors; Urinary Bladder Neoplasms | 2008 |
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure.
Topics: Acetylation; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-2 | 2009 |
Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1.
Topics: Acetylation; Analysis of Variance; Animals; Azacitidine; Brain-Derived Neurotrophic Factor; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; DNA-Binding Proteins; Embryo, Mammalian; Enzyme Inhibitors; Exons; Hippocampus; Histone Deacetylase 1; Histone Deacetylases; Histones; Hydroxamic Acids; In Vitro Techniques; Lysine; Methyl-CpG-Binding Protein 2; Methylation; N-Methylaspartate; Neurons; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Repressor Proteins; RNA, Messenger; Time Factors; Transcription Factors | 2009 |
Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells.
Topics: Acetylation; Azacitidine; Blotting, Western; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Enzyme Inhibitors; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Immunoprecipitation; Lysine; Polymerase Chain Reaction; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Cells, Cultured | 2009 |
Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines.
Topics: Azacitidine; Decitabine; Gene Silencing; Histones; Humans; Lysine; Male; Methylation; Octamer Transcription Factor-3; Proto-Oncogene Mas; Testicular Neoplasms; Tumor Suppressor Proteins | 2011 |
Active loss of DNA methylation in two-cell stage goat embryos.
Topics: 5-Methylcytosine; Animals; Azacitidine; Decitabine; DNA; DNA Methylation; DNA Modification Methylases; Embryo, Mammalian; Enzyme Inhibitors; Female; Goats; Histones; Immunohistochemistry; Lysine; Male; Methylation; Zygote | 2010 |
Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation.
Topics: Adenine Phosphoribosyltransferase; Animals; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Lysine; Methylation; Mice; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2011 |
Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery.
Topics: Azacitidine; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genetic Loci; GTPase-Activating Proteins; HCT116 Cells; HeLa Cells; Histones; Humans; Lysine; Stochastic Processes; Transcription, Genetic; Tumor Suppressor Proteins | 2011 |
Histone modifications and methyl-CpG-binding domain protein levels at the TNFSF7 (CD70) promoter in SLE CD4+ T cells.
Topics: Adolescent; Adult; Animals; Azacitidine; CD27 Ligand; CD4-Positive T-Lymphocytes; Cells, Cultured; Enzyme Inhibitors; Female; Histones; Humans; Lupus Erythematosus, Systemic; Lysine; Male; Methyl-CpG-Binding Protein 2; Middle Aged; Promoter Regions, Genetic; Young Adult | 2011 |
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines.
Topics: Acetylation; Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromosomes, Human, Pair 3; Decitabine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; Lysine; Multigene Family; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2011 |
Neonatal isolation decreases cued fear conditioning and frontal cortical histone 3 lysine 9 methylation in adult female rats.
Topics: Acoustic Stimulation; Age Factors; Animals; Animals, Newborn; Azacitidine; Behavior, Animal; Cerebral Cortex; Conditioning, Psychological; Corticosterone; Cues; Decitabine; DNA Modification Methylases; Dose-Response Relationship, Drug; Down-Regulation; Estradiol; Fear; Female; Histone Deacetylase Inhibitors; Histones; Light; Lysine; Maternal Deprivation; Methylation; Photic Stimulation; Rats; Rats, Sprague-Dawley; Reflex, Startle; Stress, Psychological; Valproic Acid | 2012 |
Epigenetic regulation of CXCR4 expression by the ocular microenvironment.
Topics: Animals; Anterior Chamber; Antimetabolites, Antineoplastic; Azacitidine; Cecum; Cell Line, Tumor; Decitabine; Down-Regulation; Epigenesis, Genetic; Flow Cytometry; Gene Expression; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Injections; Injections, Subcutaneous; Lysine; Methylation; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Promoter Regions, Genetic; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; Spleen; Up-Regulation | 2013 |
Epigenetic regulation by CpG methylation splits strong from retarded IFNγ-induced IL-18BP in epithelial versus monocytic cells.
Topics: Acetylation; Azacitidine; Cell Line; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Epithelial Cells; Histones; Humans; Intercellular Signaling Peptides and Proteins; Interferon-gamma; Lysine; Methyl-CpG-Binding Protein 2; Monocytes; Promoter Regions, Genetic; Protein Binding; RNA Polymerase II; Transcription Initiation Site; Transcription, Genetic | 2018 |
Molecular mechanisms of Guadecitabine induced FGFR4 down regulation in alveolar rhabdomyosarcomas.
Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation Sequencing; Down-Regulation; Enhancer Elements, Genetic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Nuclear Proteins; Receptor, Fibroblast Growth Factor, Type 4; Repressor Proteins; Rhabdomyosarcoma, Alveolar | 2020 |
Knockdown of
Topics: Animals; Ascorbic Acid; Azacitidine; Chickens; Histones; Lysine; Muscle Development; Myoblasts | 2022 |