Page last updated: 2024-08-17

lysine and aminocaproic acid

lysine has been researched along with aminocaproic acid in 87 studies

Research

Studies (87)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (32.18)	18.7374
1990's	29 (33.33)	18.2507
2000's	18 (20.69)	29.6817
2010's	9 (10.34)	24.3611
2020's	3 (3.45)	2.80

Authors

Authors	Studies
Barker, HA; Bozler, G; Hensley, C; Ohsugi, M; Robertson, JM	1
Christensen, U	2
Cederholm-Williams, SA; Swain, A	1
Matsuda, H; Ohashi, H; Takada, A; Takada, Y	1
de Gaetano, G; Donati, MB; Farina, ML; Langer, M	1
DePasquale, JL; Markus, G; Wissler, FC	1
Evers, JL; Hobika, GH; Markus, G	1
Castellino, FJ; De Serrano, VS; Sehl, LC	1
Christensen, U; Mølgaard, L	1
Castellino, FJ; De Serrano, VS	2
Anonick, PK; Gonias, SL; Vasudevan, J	1
Mulichak, AM; Padmanabhan, K; Tulinsky, A; Wu, TP	1
Gaffney, PJ; Longstaff, C	1
Clough, AM; Gaffney, PJ; Longstaff, C	1
Castellino, FJ; Sehl, LC	1
Lin, BH; Mangel, WF; Ramakrishnan, V	1
Kudinov, SA; Matsuka, YV; Novokhatny, VV	1
Chang, BI; Chang, LC; Gong, CC; Lou, KL; Shi, GY; Wu, DH; Wu, HL	1
Kudinov, SA; Novokhatny, VV	1
Boyle, MD; Broeseker, TA; Lottenberg, R	1
Pannekoek, H; van Zonneveld, AJ; Veerman, H	1
Castellino, FJ; Chibber, BA; Morris, JP; Smith, JH	1
Gillessen, D; Lerch, PG; Lergier, W; Rickli, EE	1
Patthy, L; Váli, Z	1
Takada, A; Takada, Y	1
Machovich, R; Owen, WG	1
Fless, GM; Hoover-Plow, JL; Miles, LA; Plow, EF; Scanu, AM	1
Boettcher, BR; LoGrasso, PV; Mikol, V	1
Bakker, AH; Nieuwenbroek, NM; Verheijen, JH	1
Boffa, MB; Gabel, BR; Hancock, MA; Horrevoets, AJ; Koschinsky, ML; Marcovina, SM; Nesheim, ME; Sangrar, W; Walker, JB	1
Fless, GM; Furbee, J; Meredith, SC; Santiago, JY	1
Arai, K; Asakura, S; Madoiwa, S; Matsuda, M; Mimuro, J; Sakata, Y; Sako, T	1
Royston, D	1
Chiu, RC; Lee, A; Pelletier, MP; Solymoss, S	1
Gabel, BR; Koschinsky, ML	1
Cederholm-Williams, SA; Cockell, CS; Dawson, KM; Marshall, JM; Ponting, CP	1
Ljungh, A; Pantzar, M; Wadström, T	1
Choi, KS; Fitzpatrick, SL; Kang, HM; Kassam, G; Le, BH; Louie, P; Waisman, DM	1
Deadman, JJ; Ellis, V; Werner, F; Whawell, SA	1
Gonias, SL; Hembrough, TA; Karns, LR; Kralovich, KR; Li, L; Webb, DJ	1
Cheng, B; Klezovitch, O; Mochalkin, I; Scanu, AM; Tulinsky, A	1
Biswas, P; Perazella, MA	1
Fless, GM; Halfman, CJ; Kirk, EW	1
Dikshit, KL; Rajamohan, G	1
Brosch, G; Hoffmann, K; Jung, M; Loidl, P	1
Bock, PE; Boxrud, PD	1
Burke, TA; Felez, J; Herren, T; Jardi, M; Plow, EF	1
Hoover-Plow, J; Yuen, L	1
Gaubatz, JW; Ghazzaly, KG; Guevara, J; Hoffman, AS; Hoogeveen, RC; Koschinsky, ML; Morrisett, JD; Pownall, HJ	1
Becker, L; Chitayat, S; Koschinsky, ML; Nesheim, ME; Webb, BA	1
Barre, D	1
NAGAMATSU, A; OKUMA, T; WATANABE, M; YAMAMURA, Y	1
DONALDSON, VH	1
LOWNEY, ED	1
ERDOES, EG; SLOANE, EM; WOHLER, IM	1
KIM, S; PAIK, WK	1
FUDENBERG, H; TAYLOR, FB	1
DAVIES, MC; DERENZO, EC; ENGLERT, ME	1
ATCHLEY, WA; BHAGAVAN, NV; MASOUREDIS, SP	1
BRADY, BL	1
ALLISON, F; LANCASTER, MG	1
FUJII, S; MAKINO, S; MURAMATU, M; ONISHI, T; YAMAMURA, Y	2
LEWANDOWSKI, V; MAXWELL, RE; NICKEL, VS	1
Bean, RR; Bock, PE; Verhamme, IM	1
Davies, MJ; Pattison, DI	1
Stief, TW	1
McMurdy, N; Trudell, J	1
Blanchevoye, C; Garnotel, R; Gillery, P; Jaisson, S; Perreau, C; Sartelet, H	1
Bock, PE; Verhamme, IM	1
Cho, T; Jung, Y; Koschinsky, ML	1
Murata, M; Ono, H; Sakamoto, J; Takenaka, M	1
Bruzgo, I; Markowska, A; Midura-Nowaczek, K; Purwin, M	1
Doctor, V; Kouemo, S; McMillan, E	1
Murata, M; Nomi, Y; Ono, H; Sakamoto, J; Takenaka, M	1
Brunskill, SJ; Doree, C; Estcourt, LJ; Murphy, MF; Stanworth, S; Trivella, M; Wardrop, D	1
Beck, A; Breau, RH; Buenaventura, C; Cagiannos, I; Cowan, J; Fergusson, DA; Knoll, G; Kokolo, MB; Momoli, F; Morash, C; Niznick, N; Punjani, N; Ruzicka, M; Schachkina, S; Tinmouth, A; Xie, HY	1
Chytil, M; Kovalenko, A; Trojan, M	1
Brunskill, SJ; Desborough, M; Doree, C; Estcourt, LJ; Hopewell, S; Murphy, MF; Stanworth, SJ	1
Breau, RH; Cagiannos, I; Cnossen, S; Fergusson, DA; Fergusson, NA; Hutton, B; Lavallée, LT; Montroy, J; Morash, C	1
Baidoo, EE; Barajas, JF; Burdu, M; Keasling, JD; Wang, G; Zhang, J	1
Chen, P; Cheng, J; Song, A; Wang, D; Wang, Q	1
Breau, RH; Cagiannos, I; Fergusson, DA; Flaman, A; Hutton, B; Lavallée, LT; Montroy, J; Morash, C; Tinmouth, A	1
Jarocka-Karpowicz, I; Markowska, A; Markowski, AR	1
Gailani, D; Ivanov, I; Law, RHP; Litvak, M; Maddur, A; McCarty, OJT; Mohammed, BM; Shaban, R; Shamanaev, A; Srivastava, P; Sun, MF; Verhamme, IM	1

Reviews

8 review(s) available for lysine and aminocaproic acid

Article	Year
Aprotinin versus lysine analogues: the debate continues. The Annals of thoracic surgery, 1998, Volume: 65, Issue:4 Suppl Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Transfusion; Cardiac Surgical Procedures; Hemostasis, Surgical; Hemostatics; Humans; Lysine; Tranexamic Acid	1998
Current antifibrinolytic therapy for coronary artery revascularization. AANA journal, 2008, Volume: 76, Issue:2 Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; Humans; Lysine; Patient Selection; Postoperative Hemorrhage; Risk Factors; Safety Management; Serine Proteinase Inhibitors; Tranexamic Acid; Treatment Outcome	2008
Antifibrinolytics (lysine analogues) for the prevention of bleeding in patients with haematological disorders. The Cochrane database of systematic reviews, 2013, Jul-29, Issue:7 Topics: Aminocaproic Acid; Antifibrinolytic Agents; Erythrocyte Transfusion; Hematologic Diseases; Hemorrhage; Humans; Lysine; Platelet Transfusion; Thrombocytopenia; Tranexamic Acid	2013
The effects of lysine analogs during pelvic surgery: a systematic review and meta-analysis. Transfusion medicine reviews, 2014, Volume: 28, Issue:3 Topics: Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Gynecologic Surgical Procedures; Hemorrhage; Humans; Lysine; Randomized Controlled Trials as Topic; Risk; Surgical Procedures, Operative; Thrombosis; Tranexamic Acid; Treatment Outcome; Urologic Surgical Procedures, Male	2014
Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disorders. The Cochrane database of systematic reviews, 2016, Mar-15, Volume: 3 Topics: Aminocaproic Acid; Antifibrinolytic Agents; Erythrocyte Transfusion; Hematologic Diseases; Hemorrhage; Humans; Lysine; Platelet Transfusion; Thrombocytopenia; Thromboembolism; Tranexamic Acid	2016
The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis. Transfusion medicine reviews, 2017, Volume: 31, Issue:3 Topics: Adult; Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Erythrocyte Transfusion; Humans; Lysine; Neoplasms; Patient Safety; Platelet Transfusion; Randomized Controlled Trials as Topic; Tranexamic Acid; Treatment Outcome; Venous Thrombosis	2017
Expanding lysine industry: industrial biomanufacturing of lysine and its derivatives. Journal of industrial microbiology & biotechnology, 2018, Volume: 45, Issue:8 Topics: Amino Acids; Amino Acids, Neutral; Aminocaproic Acid; Biocompatible Materials; Cadaverine; Caprolactam; Chemistry, Pharmaceutical; Corynebacterium glutamicum; Escherichia coli; Fermentation; Green Chemistry Technology; Industrial Microbiology; Lactams; Lysine; Pipecolic Acids; Piperidones; Polymers	2018
The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element. International journal of molecular sciences, 2021, Nov-09, Volume: 22, Issue:22 Topics: Amino Acid Sequence; Amino Acids; Aminocaproic Acid; Antifibrinolytic Agents; Binding Sites; Humans; Hydrophobic and Hydrophilic Interactions; Lysine; Peptides	2021

Other Studies

79 other study(ies) available for lysine and aminocaproic acid

Article	Year
Metabolism of L-beta-lysine in a Pseudomonas: conversion of 6-N-acetyl-L-beta-lysine to 3-keto-6-acetamidohexanoate and of 4-aminobutyrate to succinic semialdehyde by different transaminases. Archives of biochemistry and biophysics, 1979, Oct-01, Volume: 197, Issue:1 Topics: Aminocaproates; Aminocaproic Acid; Enzyme Induction; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Pseudomonas; Pyridoxal Phosphate; Pyruvates; Substrate Specificity; Transaminases	1979
Allosteric effects of some antifibrinolytic amino acids on the catalytic activity of human plasmin. Biochimica et biophysica acta, 1978, Sep-11, Volume: 526, Issue:1 Topics: Allosteric Regulation; Allosteric Site; Aminocaproic Acid; Antifibrinolytic Agents; Binding Sites; Catalysis; Enzyme Activation; Fibrinolysin; Humans; Kinetics; Lysine; Mathematics; Tranexamic Acid	1978
The effect of fibrinogen degradation products and some lysine analogues on the dissociation of plasmin(ogen)-fibrin complexes. Thrombosis research, 1979, Volume: 16, Issue:5-6 Topics: Aminocaproic Acid; Animals; Cattle; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Fibrinolysis; Humans; Lysine; Plasminogen; Protein Binding; Tranexamic Acid	1979
Effects of tranexamic acid, cis-AMCHA, and 6-aminohexanoic acid on the activation rate of plasminogen by urokinase in the presence of clot. Thrombosis research, 1979, Volume: 14, Issue:6 Topics: Aminocaproates; Aminocaproic Acid; Animals; Antifibrinolytic Agents; Blood Coagulation; Cattle; Cyclohexanecarboxylic Acids; Endopeptidases; Humans; Isomerism; Lysine; Oligopeptides; Plasminogen; Thrombin; Tranexamic Acid; Urokinase-Type Plasminogen Activator	1979
Antiplatelet treatment in septic shock with severe bleeding and thrombocytopenia. Thrombosis and haemostasis, 1977, Aug-31, Volume: 38, Issue:2 Topics: Adult; Aminocaproic Acid; Aspirin; Dipyridamole; Female; Humans; Lysine; Platelet Aggregation; Purpura, Thrombotic Thrombocytopenic; Shock, Septic	1977
Quantitative determination of the binding of epsilon-aminocaproic acid to native plasminogen. The Journal of biological chemistry, 1978, Feb-10, Volume: 253, Issue:3 Topics: Aminocaproates; Aminocaproic Acid; Binding, Competitive; Humans; Lysine; Plasminogen; Protein Binding; Ultrafiltration	1978
Comparison of some properties of native (Glu) and modified (Lys) human plasminogen. The Journal of biological chemistry, 1978, Feb-10, Volume: 253, Issue:3 Topics: Aminocaproic Acid; Enzyme Activation; Glutamates; Humans; Lysine; Plasminogen; Protein Conformation; Streptokinase	1978
Direct identification of lysine-33 as the principal cationic center of the omega-amino acid binding site of the recombinant kringle 2 domain of tissue-type plasminogen activator. Archives of biochemistry and biophysics, 1992, Volume: 292, Issue:1 Topics: Amino Acid Sequence; Aminocaproic Acid; Base Sequence; Binding Sites; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Conformation; Recombinant Proteins; Structure-Activity Relationship; Tissue Plasminogen Activator	1992
Positive co-operative binding at two weak lysine-binding sites governs the Glu-plasminogen conformational change. The Biochemical journal, 1992, Jul-15, Volume: 285 ( Pt 2) Topics: Aminocaproic Acid; Binding Sites; Fluorescence Polarization; Humans; Kinetics; Lysine; Peptide Fragments; Plasminogen; Protein Conformation; Tranexamic Acid	1992
The cationic locus on the recombinant kringle 2 domain of tissue-type plasminogen activator that stabilizes its interaction with omega-amino acids. Biochemistry, 1992, Dec-01, Volume: 31, Issue:47 Topics: Amino Acid Sequence; Amino Acids; Aminocaproic Acid; Base Sequence; Binding Sites; Cations; DNA; Enzyme Stability; Escherichia coli; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Peptide Fragments; Plasmids; Recombinant Proteins; Tissue Plasminogen Activator; Tranexamic Acid	1992
Antifibrinolytic activities of alpha-N-acetyl-L-lysine methyl ester, epsilon-aminocaproic acid, and tranexamic acid. Importance of kringle interactions and active site inhibition. Arteriosclerosis and thrombosis : a journal of vascular biology, 1992, Volume: 12, Issue:6 Topics: alpha-Macroglobulins; Amidohydrolases; Aminocaproic Acid; Binding Sites; Binding, Competitive; Blood Coagulation; Fibrinolysin; Fibrinolysis; Humans; Kinetics; Lysine; Peptide Fragments; Serum Globulins; Tranexamic Acid	1992
The refined structure of the epsilon-aminocaproic acid complex of human plasminogen kringle 4. Biochemistry, 1991, Oct-29, Volume: 30, Issue:43 Topics: Amino Acid Sequence; Aminocaproic Acid; Binding Sites; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Plasminogen; X-Ray Diffraction	1991
Serpin-serine protease binding kinetics: alpha 2-antiplasmin as a model inhibitor. Biochemistry, 1991, Jan-29, Volume: 30, Issue:4 Topics: alpha-Macroglobulins; Aminocaproic Acid; Binding Sites; Chymotrypsin; Fibrinolysin; Humans; Kinetics; Lysine; Models, Biological; Structure-Activity Relationship; Thermodynamics; Tranexamic Acid	1991
Kinetics of plasmin activation of single chain urinary-type plasminogen activator (scu-PA) and demonstration of a high affinity interaction between scu-PA and plasminogen. The Journal of biological chemistry, 1992, Jan-05, Volume: 267, Issue:1 Topics: Aminocaproic Acid; Enzyme Activation; Glutamine; Humans; Kinetics; Lysine; Molecular Conformation; Plasminogen; Protein Precursors; Substrate Specificity; Urokinase-Type Plasminogen Activator	1992
Thermodynamic properties of the binding of alpha-, omega-amino acids to the isolated kringle 4 region of human plasminogen as determined by high sensitivity titration calorimetry. The Journal of biological chemistry, 1990, Apr-05, Volume: 265, Issue:10 Topics: Amino Acid Sequence; Amino Acids; Aminocaproates; Aminocaproic Acid; beta-Alanine; Binding Sites; Calorimetry; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Plasminogen; Structure-Activity Relationship; Thermodynamics	1990
Characterization of an extremely large, ligand-induced conformational change in plasminogen. Science (New York, N.Y.), 1990, Apr-06, Volume: 248, Issue:4951 Topics: Aminocaproic Acid; Binding Sites; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Deuterium; Humans; Lysine; Neutrons; Plasminogen; Plasminogen Activators; Protein Conformation; Scattering, Radiation; Urokinase-Type Plasminogen Activator; Water	1990
Fluorescence spectroscopic analysis of ligand binding to kringle 1 + 2 + 3 and kringle 1 fragments from human plasminogen. European journal of biochemistry, 1990, May-31, Volume: 190, Issue:1 Topics: Amines; Aminocaproic Acid; Arginine; Binding Sites; Humans; Ligands; Lysine; Pepsin A; Peptide Fragments; Plasminogen; Spectrometry, Fluorescence	1990
Interaction of plasminogen and fibrin in plasminogen activation. The Journal of biological chemistry, 1990, Nov-15, Volume: 265, Issue:32 Topics: Aminocaproic Acid; Fibrin; Fibrin Fibrinogen Degradation Products; Humans; Kinetics; Lysine; Molecular Weight; Peptide Fragments; Plasminogen; Tissue Plasminogen Activator	1990
Analysis of ligand binding to kringles 4 and 5 fragments from human plasminogen. Thrombosis research, 1989, Feb-01, Volume: 53, Issue:3 Topics: Amines; Aminocaproic Acid; Arginine; Binding Sites; Humans; In Vitro Techniques; Kinetics; Lysine; Pentanoic Acids; Plasminogen; Thermodynamics	1989
Characterization of the interaction of human plasmin with its specific receptor on a group A streptococcus. Microbial pathogenesis, 1988, Volume: 5, Issue:1 Topics: Aminocaproic Acid; Arginine; Binding, Competitive; Cations, Divalent; Fibrinolysin; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Plasminogen; Streptococcus pyogenes	1988
On the interaction of the finger and the kringle-2 domain of tissue-type plasminogen activator with fibrin. Inhibition of kringle-2 binding to fibrin by epsilon-amino caproic acid. The Journal of biological chemistry, 1986, Oct-25, Volume: 261, Issue:30 Topics: Aminocaproates; Aminocaproic Acid; Animals; Binding Sites; Chromatography, Affinity; Fibrin; Humans; Lysine; Mice; Peptide Fragments; Protein Conformation; Recombinant Proteins; Tissue Plasminogen Activator	1986
The role of the lysine binding sites of human plasminogen in the fibrinogen stimulated rate of active site formation in the streptokinase-plasminogen equimolar complex. Thrombosis research, 1984, Jun-15, Volume: 34, Issue:6 Topics: Aminocaproic Acid; Binding Sites; Chemical Phenomena; Chemistry; Fibrin Fibrinogen Degradation Products; Humans; Kinetics; Lysine; Plasminogen; Streptokinase	1984
The AH-site of plasminogen and two C-terminal fragments. A weak lysine-binding site preferring ligands not carrying a free carboxylate function. The Biochemical journal, 1984, Oct-15, Volume: 223, Issue:2 Topics: Aminocaproates; Aminocaproic Acid; Binding Sites; Chromatography, Affinity; Ligands; Lysine; Macromolecular Substances; Models, Biological; Plasminogen	1984
Localization of individual lysine-binding regions in human plasminogen and investigations on their complex-forming properties. European journal of biochemistry, 1980, Volume: 107, Issue:1 Topics: Amino Acid Sequence; Aminocaproic Acid; Binding Sites; Chymotrypsin; Humans; Kinetics; Lysine; Pancreatic Elastase; Peptide Fragments; Plasminogen; Protein Binding; Protein Conformation	1980
Essential carboxyl- and guanidino-group in the lysine-binding site of human plasminogen. Biochemical and biophysical research communications, 1980, Oct-31, Volume: 96, Issue:4 Topics: Aminocaproic Acid; Binding Sites; Ethyldimethylaminopropyl Carbodiimide; Humans; Kinetics; Lysine; Plasminogen; Protein Binding; Sepharose	1980
Influence of omega-aminoacids on the activation of the first component of complement at low ionic strength. Thrombosis and haemostasis, 1981, Feb-23, Volume: 45, Issue:1 Topics: Amino Acids; Aminocaproic Acid; Arginine; Complement Activation; Complement C1; Humans; Hydrogen-Ion Concentration; Lysine; Ornithine	1981
Facilitation of plasminogen activation by a plasmin substrate containing a lysyl residue. Thrombosis and haemostasis, 1993, Nov-15, Volume: 70, Issue:5 Topics: Aminocaproic Acid; Animals; Binding Sites; Enzyme Activation; Fibrinolysin; Humans; Hydrolysis; Kringles; Lysine; Oligopeptides; Plasminogen; Substrate Specificity; Swine; Urokinase-Type Plasminogen Activator	1993
Comparison of the lysine binding functions of lipoprotein(a) and plasminogen. Biochemistry, 1993, Dec-14, Volume: 32, Issue:49 Topics: Acetylation; Amino Acid Sequence; Aminocaproic Acid; Binding Sites; Humans; Hydrogen-Ion Concentration; Iodine Radioisotopes; Kringles; Lipoprotein(a); Lysine; Molecular Sequence Data; Plasminogen; Sepharose; Sequence Homology; Structure-Activity Relationship; Tranexamic Acid	1993
Specific anionic residues of the recombinant kringle 2 domain of tissue-type plasminogen activator that are responsible for stabilization of its interaction with omega-amino acid ligands. Biochemistry, 1993, Apr-13, Volume: 32, Issue:14 Topics: Amino Acid Sequence; Amino Acids; Aminocaproic Acid; Anions; Base Sequence; Binding Sites; Escherichia coli; Lysine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Peptide Fragments; Recombinant Proteins; Thermodynamics; Tissue Plasminogen Activator; Tranexamic Acid; X-Ray Diffraction	1993
Crystal structures of apolipoprotein(a) kringle IV37 free and complexed with 6-aminohexanoic acid and with p-aminomethylbenzoic acid: existence of novel and expected binding modes. Journal of molecular biology, 1996, Mar-08, Volume: 256, Issue:4 Topics: 4-Aminobenzoic Acid; Amino Acid Sequence; Aminocaproic Acid; Apolipoproteins A; Binding Sites; Crystallization; Crystallography, X-Ray; Kringles; Ligands; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; para-Aminobenzoates; Plasminogen; Protein Binding; Sequence Alignment	1996
Domain-domain interactions in hybrids of tissue-type plasminogen activator and urokinase-type plasminogen activator. Protein engineering, 1995, Volume: 8, Issue:12 Topics: Amino Acid Sequence; Aminocaproic Acid; Animals; Base Sequence; Binding Sites; CHO Cells; Chromatography, Affinity; Cloning, Molecular; Consensus Sequence; Cricetinae; DNA Primers; Electrophoresis, Polyacrylamide Gel; Fibrin; Kringles; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Engineering; Recombinant Proteins; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	1995
The solution phase interaction between apolipoprotein(a) and plasminogen inhibits the binding of plasminogen to a plasmin-modified fibrinogen surface. Biochemistry, 1997, Aug-26, Volume: 36, Issue:34 Topics: Aminocaproic Acid; Apolipoproteins A; Binding Sites; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Fibrinolysin; Fluorescent Dyes; Humans; Kidney; Kringles; Lysine; Mutagenesis; Plasminogen; Protein Binding; Recombinant Proteins	1997
Specificity of ligand-induced conformational change of lipoprotein(a). Biochemistry, 1997, Sep-23, Volume: 36, Issue:38 Topics: Aminocaproic Acid; Glutamic Acid; Ligands; Lipoprotein(a); Lysine; Models, Chemical; Molecular Weight; Osmolar Concentration; Particle Size; Proline; Protein Conformation; Protein Denaturation; Salts; Tranexamic Acid; Ultracentrifugation	1997
Role of the kringle domain in plasminogen activation with staphylokinase. Journal of biochemistry, 1998, Volume: 123, Issue:1 Topics: Aminocaproic Acid; Binding Sites; Catalysis; Fibrinolysin; Humans; Kringles; Lysine; Metalloendopeptidases; Plasminogen; Protein Binding; Recombinant Proteins	1998
Negative reexploration for cardiac postoperative bleeding: can it be therapeutic? The Annals of thoracic surgery, 1998, Volume: 65, Issue:4 Topics: Aged; alpha-2-Antiplasmin; Aminocaproic Acid; Antifibrinolytic Agents; Antithrombins; Aortic Valve; Blood Coagulation; Capillaries; Cardiac Surgical Procedures; Coronary Artery Bypass; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinolysis; Fibrinolytic Agents; Hemostasis, Surgical; Hemostatics; Humans; Lysine; Mediastinum; Microcirculation; Mitral Valve; Plasminogen Activator Inhibitor 1; Postoperative Hemorrhage; Reoperation; Serine Proteinase Inhibitors; Therapeutic Irrigation	1998
Sequences within apolipoprotein(a) kringle IV types 6-8 bind directly to low-density lipoprotein and mediate noncovalent association of apolipoprotein(a) with apolipoprotein B-100. Biochemistry, 1998, May-26, Volume: 37, Issue:21 Topics: Aminocaproic Acid; Apolipoprotein B-100; Apolipoproteins; Apolipoproteins B; Apoprotein(a); Humans; Kringles; Lipoprotein(a); Lipoproteins, LDL; Lysine; Proline; Protein Binding; Radioligand Assay; Recombinant Proteins	1998
Evidence that the conformation of unliganded human plasminogen is maintained via an intramolecular interaction between the lysine-binding site of kringle 5 and the N-terminal peptide. The Biochemical journal, 1998, Jul-01, Volume: 333 ( Pt 1) Topics: Amino Acid Substitution; Aminocaproic Acid; Animals; Binding Sites; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Enzyme Activation; Glutamic Acid; Humans; Kringles; Ligands; Lysine; Molecular Weight; Mutagenesis, Site-Directed; Plasminogen; Protein Conformation; Recombinant Proteins; Urokinase-Type Plasminogen Activator	1998
Plasminogen binding and activation at the surface of Helicobacter pylori CCUG 17874. Infection and immunity, 1998, Volume: 66, Issue:10 Topics: Aminocaproic Acid; Binding, Competitive; Chromogenic Compounds; Enzyme Activation; Helicobacter pylori; Kringles; Lysine; Membrane Proteins; Oligopeptides; Peptide Fragments; Plasminogen; Plasminogen Activators; Protein Binding	1998
The p11 subunit of the annexin II tetramer plays a key role in the stimulation of t-PA-dependent plasminogen activation. Biochemistry, 1998, Dec-01, Volume: 37, Issue:48 Topics: alpha-2-Antiplasmin; Aminocaproic Acid; Annexin A2; Cells, Cultured; Enzyme Activation; Fibrinolysin; Humans; Lysine; Mutagenesis; Plasminogen; Plasminogen Activator Inhibitor 1; Receptors, Cell Surface; Recombinant Proteins; Sequence Deletion; Tissue Plasminogen Activator	1998
Assembly of urokinase receptor-mediated plasminogen activation complexes involves direct, non-active-site interactions between urokinase and plasminogen. Biochemistry, 1999, Jan-12, Volume: 38, Issue:2 Topics: Aminocaproic Acid; Binding Sites; Biosensing Techniques; Cell Membrane; Enzyme Activation; Enzyme Inhibitors; Humans; Lysine; Macromolecular Substances; Oligopeptides; Peptide Fragments; Plasminogen; Plasminogen Activators; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; U937 Cells; Urokinase-Type Plasminogen Activator	1999
Characterization of the binding sites for plasminogen and tissue-type plasminogen activator in cytokeratin 8 and cytokeratin 18. Journal of protein chemistry, 1998, Volume: 17, Issue:8 Topics: Aminocaproic Acid; Binding Sites; Binding, Competitive; Dimerization; Glutathione Transferase; Keratins; Lysine; Mutation; Plasminogen; Recombinant Fusion Proteins; Solutions; Tissue Plasminogen Activator	1998
Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance. Biochemistry, 1999, Feb-16, Volume: 38, Issue:7 Topics: Aminocaproic Acid; Apolipoproteins A; Arginine; Crystallization; Crystallography, X-Ray; Humans; Ligands; Lysine; Models, Molecular; Peptide Fragments; Protein Binding; Recombinant Proteins	1999
Acute hyperkalemia associated with intravenous epsilon-aminocaproic acid therapy. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 33, Issue:4 Topics: Acute Disease; Aged; Aminocaproic Acid; Arginine; Blood Loss, Surgical; Coronary Artery Bypass; Humans; Hyperkalemia; Kidney Failure, Chronic; Lysine; Male; Postoperative Complications	1999
The relationship between the effect of lysine analogues and salt on the conformation of lipoprotein(a). Biochemistry, 2000, Mar-14, Volume: 39, Issue:10 Topics: Aminocaproic Acid; Citrates; Humans; Kringles; Lipoprotein(a); Lysine; Models, Chemical; Protein Binding; Protein Conformation; Salts; Sodium Chloride; Sodium Citrate; Sodium Iodide	2000
Role of the N-terminal region of staphylokinase (SAK): evidence for the participation of the N-terminal region of SAK in the enzyme-substrate complex formation. FEBS letters, 2000, Jun-02, Volume: 474, Issue:2-3 Topics: Amino Acid Sequence; Amino Acid Substitution; Aminocaproic Acid; Binding Sites; Catalysis; Dose-Response Relationship, Drug; Fibrinolysin; Humans; Iodine Radioisotopes; Kinetics; Kringles; Lysine; Metalloendopeptidases; Molecular Sequence Data; Mutation; Peptide Fragments; Plasminogen; Plasminogen Activators; Protein Binding; Protein Processing, Post-Translational; Staphylococcus aureus	2000
First non-radioactive assay for in vitro screening of histone deacetylase inhibitors. Die Pharmazie, 2000, Volume: 55, Issue:8 Topics: Aminocaproic Acid; Animals; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescent Dyes; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Liver; Lysine; Rats; Spectrometry, Fluorescence	2000
Streptokinase binds preferentially to the extended conformation of plasminogen through lysine binding site and catalytic domain interactions. Biochemistry, 2000, Nov-14, Volume: 39, Issue:45 Topics: Amino Acid Chloromethyl Ketones; Aminocaproic Acid; Binding Sites; Catalytic Domain; Chlorides; Fibrinolysin; Glutamic Acid; Humans; Lysine; Plasminogen; Protein Conformation; Serine Proteinase Inhibitors; Streptokinase	2000
Regulation of plasminogen binding to neutrophils. Blood, 2001, Feb-15, Volume: 97, Issue:4 Topics: Amino Acid Chloromethyl Ketones; Aminocaproic Acid; Animals; Aprotinin; Carboxypeptidase B; Carboxypeptidases; Cathepsin G; Cathepsins; Cell Line; Cells, Cultured; Drug Synergism; Enzyme Activation; Fibrinolysin; Humans; Leukocyte Elastase; Lysine; Mice; Mice, Inbred C57BL; Neutrophils; Peritonitis; Plasminogen; Protease Inhibitors; Protein Binding; Proteins; Respiratory Burst; Serine Endopeptidases; Serpins; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Trypsin Inhibitor, Kunitz Soybean; U937 Cells	2001
Plasminogen binding is increased with adipocyte differentiation. Biochemical and biophysical research communications, 2001, Jun-08, Volume: 284, Issue:2 Topics: 3T3 Cells; Adipocytes; Aminocaproic Acid; Animals; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Ligands; Lysine; Mice; Mice, Knockout; Plasminogen; Protein Binding; Stromal Cells; Tranexamic Acid	2001
Isolation, quantitation, and characterization of a stable complex formed by Lp[a] binding to triglyceride-rich lipoproteins. Journal of lipid research, 2001, Volume: 42, Issue:12 Topics: Aminocaproic Acid; Apolipoproteins A; Arginine; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Hypertriglyceridemia; Immunoblotting; Lipoprotein(a); Lysine; Macromolecular Substances; Molecular Weight; Plasmapheresis; Proline; Protein Binding; Tranexamic Acid; Triglycerides; Ultracentrifugation	2001
A ligand-induced conformational change in apolipoprotein(a) enhances covalent Lp(a) formation. The Journal of biological chemistry, 2003, Apr-18, Volume: 278, Issue:16 Topics: Aminocaproic Acid; Apolipoproteins; Apoprotein(a); Calorimetry, Differential Scanning; Cell Line; Disulfides; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Kinetics; Ligands; Lipoprotein(a); Lysine; Models, Biological; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Temperature; Transfection; Tryptophan; Ultracentrifugation; Water	2003
Human lipoprotein (a)-induced reduction of platelet aggregation is not mediated by apolipoprotein A's lysine-binding regions. Frontiers in bioscience : a journal and virtual library, 2003, Sep-01, Volume: 8 Topics: Aminocaproic Acid; Apolipoproteins A; Binding Sites; Humans; Lipoprotein(a); Lysine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding; Protein Structure, Tertiary; Tumor Cells, Cultured; U937 Cells	2003
THE INHIBITION OF PLASMIN BY SOME AMINO ACID DERIVATIVES. Journal of biochemistry, 1963, Volume: 54 Topics: Aminocaproates; Aminocaproic Acid; Arginine; Enzyme Inhibitors; Fibrinolysin; Lysine; Research; Spectrophotometry	1963
ACTIVATION OF PARTIALLY PURIFIED PLASMINOGEN IN THE PRESENCE OF EPSILON-AMINOCAPROIC ACID. A TECHNIQUE FOR PREPARING PLASMIN FREE OF EXTRINSIC ACTIVATORS. The Journal of laboratory and clinical medicine, 1964, Volume: 63 Topics: Aminocaproates; Aminocaproic Acid; Caseins; Deoxyribonuclease I; Fibrinolysin; Fibrinolysis; Lysine; Plasminogen; Research; Sodium Chloride; Streptodornase and Streptokinase; Streptokinase	1964
EFFECTS OF EPSILON-AMINOCAPROIC ACID ON THE TUBERCULIN REACTION IN MAN. The Journal of investigative dermatology, 1964, Volume: 42 Topics: Aminocaproates; Aminocaproic Acid; Histamine; Lysine; Pharmacology; Pheniramine; Tuberculin; Tuberculin Test	1964
CARBOXYPEPTIDASE IN BLOOD AND OTHER FLUIDS. I. PROPERTIES, DISTRIBUTION, AND PARTIAL PURIFICATION OF THE ENZYME. Biochemical pharmacology, 1964, Volume: 13 Topics: Aminocaproates; Aminocaproic Acid; Arginine; Blood; Carboxypeptidases; Chromatography; Guinea Pigs; Humans; Lymph; Lysine; Ornithine; Pancreas; Peptides; Phenylalanine; Research; Spectrophotometry; Urine	1964
COLORIMETRIC DIFFERENTIATION OF ALPHA- AND EPSILON-N-SUBSTITUTED LYSINE DERIVATIVES. Nature, 1964, May-23, Volume: 202 Topics: Aminocaproates; Aminocaproic Acid; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Colorimetry; Lysine; Ornithine; Research	1964
INHIBITION OF THE C'-1 COMPONENT OF COMPLEMENT BY AMINO ACIDS. Immunology, 1964, Volume: 7 Topics: Amino Acids; Aminocaproates; Aminocaproic Acid; Calcium Chloride; Complement System Proteins; Dialysis; Erythrocytes; Esterases; Hemolysis; Lysine; Pharmacology; Plasminogen; Renal Dialysis; Research	1964
INTERACTION OF STREPTOKINASE AND HUMAN PLASMINOGEN. I. COMBINING OF STREPTOKINASE AND PLASMINOGEN OBSERVED IN THE ULTRACENTRIFUGE UNDER A VARIETY OF EXPERIMENTAL CONDITIONS. The Journal of biological chemistry, 1964, Volume: 239 Topics: Albumins; Aminocaproates; Aminocaproic Acid; Chromatography; Deoxyribonuclease I; gamma-Globulins; Humans; Lysine; Plasminogen; Streptodornase and Streptokinase; Streptokinase; Ultracentrifugation	1964
INFLUENCE OF IONIC STRENGTH ON THE REACTION BETWEEN ANTI-D AND D POSITIVE RED CELLS. Journal of immunology (Baltimore, Md. : 1950), 1964, Volume: 93 Topics: Absorption; Aminocaproates; Aminocaproic Acid; Antigen-Antibody Reactions; Arginine; Buffers; Carbohydrates; Erythrocytes; Ethylamines; Glycine; Iodine Isotopes; Isoantibodies; Lactose; Lysine; Osmolar Concentration; Radiometry; Research; Rho(D) Immune Globulin; Sucrose	1964
UTILIZATION OF AMINO COMPOUNDS BY YEASTS OF THE GENUS SACCHAROMYCES. Antonie van Leeuwenhoek, 1965, Volume: 31 Topics: Amines; Amino Acids; Aminobutyrates; Aminocaproates; Aminocaproic Acid; Aniline Compounds; Ethylamines; Glucosamine; Guanidines; Lysine; Metabolism; Research; Saccharomyces; Spermine; Urea; Yeasts	1965
PATHOGENESIS OF ACUTE INFLAMMATION. VI. INFLUENCE OF OSMOLARITY AND CERTAIN METABOLIC ANTAGONISTS UPON PHAGOCYTOSIS AND ADHESIVENESS BY LEUCOCYTES RECOVERED FROM MAN. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119 Topics: Adhesiveness; Aminocaproates; Aminocaproic Acid; Citrulline; Dinitrophenols; Edetic Acid; Glycine; Hypertonic Solutions; Inflammation; Isoflurophate; Leukocytes; Lysine; Neutrophils; Ornithine; Osmolar Concentration; Pathology; Phagocytosis; Pharmacology; Pralidoxime Compounds; Quinidine; Research	1965
INHIBITION OF CASEINOLYTIC ACTIVITY OF PLASMIN BY VARIOUS SYNTHETIC INHIBITORS. Journal of biochemistry, 1965, Volume: 57 Topics: Aminocaproates; Aminocaproic Acid; Caseins; Enzyme Inhibitors; Fibrinolysin; Fibrinolysis; Lysine; Research; Sulfonic Acids; Toluene	1965
INHIBITION OF FIBRINOLYTIC ACTIVITY OF PLASMIN BY VARIOUS SYNTHETIC INHIBITORS. Journal of biochemistry, 1965, Volume: 57 Topics: Aminocaproates; Aminocaproic Acid; Enzyme Inhibitors; Fibrinolysin; Fibrinolysis; Lysine; Pharmacology; Research	1965
EFFECTS OF SOME AMINO ACIDS ON THE INHIBITION OF PLASMIN BY ANTIPLASMIN. Biochimica et biophysica acta, 1965, May-18, Volume: 99 Topics: Amino Acids; Aminobutyrates; Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arginine; Citrulline; Enzyme Inhibitors; Fatty Acids; Fibrinolysin; Kinetics; Lysine; Ornithine; Research	1965
Role of the streptokinase alpha-domain in the interactions of streptokinase with plasminogen and plasmin. The Journal of biological chemistry, 2005, Mar-04, Volume: 280, Issue:9 Topics: Aminocaproic Acid; Binding Sites; Catalysis; Catalytic Domain; Chlorine; Fibrinolysin; Gene Deletion; Humans; Lipopolysaccharides; Lysine; Microscopy, Fluorescence; Mutation; Plasminogen; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Streptokinase; Thermodynamics	2005
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation. Biochemistry, 2005, May-17, Volume: 44, Issue:19 Topics: Amides; Amines; Aminocaproic Acid; Arginine; Chloramines; Chromatography, High Pressure Liquid; Glycine; Histidine; Hypochlorous Acid; Imidazoles; Kinetics; Lysine; Oligopeptides; Oxidation-Reduction; Protein Conformation; Tyrosine	2005
In vitro simulation of thrombolysis inhibition. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2008, Volume: 14, Issue:2 Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Humans; Lysine; Tranexamic Acid	2008
Involvement of lysine 1047 in type I collagen-mediated activation of polymorphonuclear neutrophils. The FEBS journal, 2008, Volume: 275, Issue:12 Topics: Amino Acid Sequence; Aminocaproic Acid; Animals; Collagen Type I; Cyanogen Bromide; Humans; Lysine; Molecular Sequence Data; Neutrophil Activation; Neutrophils; Peptides; Rats; Rats, Sprague-Dawley	2008
Rapid-reaction kinetic characterization of the pathway of streptokinase-plasmin catalytic complex formation. The Journal of biological chemistry, 2008, Sep-19, Volume: 283, Issue:38 Topics: Aminocaproic Acid; Benzamidines; Binding Sites; Catalysis; Fibrinolysin; Gene Deletion; Humans; Kinetics; Ligands; Lysine; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Streptokinase	2008
Apolipoprotein(a), through its strong lysine-binding site in KIV(10'), mediates increased endothelial cell contraction and permeability via a Rho/Rho kinase/MYPT1-dependent pathway. The Journal of biological chemistry, 2008, Nov-07, Volume: 283, Issue:45 Topics: Actins; Amides; Aminocaproic Acid; Antifibrinolytic Agents; Apolipoproteins A; Atherosclerosis; Binding Sites; Capillary Permeability; Cell Line; Cytoskeleton; Endothelial Cells; Enzyme Inhibitors; Humans; Lysine; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Phosphorylation; Plasminogen; Protein Structure, Tertiary; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Sequence Homology, Amino Acid; Signal Transduction	2008
Novel yellow compounds, dilysyldipyrrolones A and B, formed from xylose and lysine by the Maillard reaction. Bioscience, biotechnology, and biochemistry, 2009, Volume: 73, Issue:9 Topics: Aminocaproates; Aminocaproic Acid; Chromatography, High Pressure Liquid; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Models, Molecular; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Xylose	2009
Short peptides containing L-lysine and epsilon-aminocaproic acid as potential plasmin inhibitors. Die Pharmazie, 2009, Volume: 64, Issue:11 Topics: Aminocaproic Acid; Buffers; Fibrinolysin; Fibrinolytic Agents; Lysine; Magnetic Resonance Spectroscopy; Peptides; Structure-Activity Relationship; Thrombin; Trypsin Inhibitors	2009
Mechanism of the synergistic effect between oversulfated chondroitin-6-sulfate and lysine or 6-aminohexanoic acid in enhancing the in-vitro activation of glutamic plasminogen by tissue plasminogen activator or urokinase. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2010, Volume: 21, Issue:5 Topics: Aminocaproic Acid; Chondroitin Sulfates; Drug Synergism; Humans; Lysine; Plasminogen; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	2010
Conditions for the formation of dilysyl-dipyrrolones A and B, and novel yellow dipyrrolone derivatives formed from xylose and amino acids in the presence of lysine. Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:2 Topics: Aminocaproates; Aminocaproic Acid; Hydrogen-Ion Concentration; Lysine; Maillard Reaction; Pyrroles; Solutions; Xylose	2011
Study on mutual interactions and electronic structures of hyaluronan with Lysine, 6-Aminocaproic acid and Arginine. Carbohydrate polymers, 2016, May-20, Volume: 142 Topics: Aminocaproic Acid; Arginine; Binding Sites; Hyaluronic Acid; Lysine; Models, Molecular; Viscosity	2016
Application of an Acyl-CoA Ligase from Streptomyces aizunensis for Lactam Biosynthesis. ACS synthetic biology, 2017, 05-19, Volume: 6, Issue:5 Topics: Amino Acids, Neutral; Aminocaproic Acid; Bacterial Proteins; Coenzyme A Ligases; gamma-Aminobutyric Acid; Lactams; Lysine; Open Reading Frames; Streptomyces	2017
Lysine analogue use during cancer surgery: a survey from a Canadian tertiary care centre. Current oncology (Toronto, Ont.), 2020, Volume: 27, Issue:6 Topics: Aminocaproic Acid; Blood Loss, Surgical; Humans; Lysine; Neoplasms; Ontario; Surveys and Questionnaires; Tertiary Care Centers; Tranexamic Acid	2020
Model for surface-dependent factor XII activation: the roles of factor XII heavy chain domains. Blood advances, 2022, 05-24, Volume: 6, Issue:10 Topics: Aminocaproic Acid; Blood Coagulation; Factor XII; Fibronectins; Lysine; Prekallikrein	2022